Page last updated: 2024-08-21

chenodeoxycholic acid and pravastatin

chenodeoxycholic acid has been researched along with pravastatin in 11 studies

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (36.36)18.2507
2000's4 (36.36)29.6817
2010's2 (18.18)24.3611
2020's1 (9.09)2.80

Authors

AuthorsStudies
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Kubo, M; Matsuzawa, Y; Miki, H; Nakamura, T; Takemura, K; Tarui, S1
Fujiyama, J; Kuriyama, M; Osame, M; Tokimura, Y; Utatsu, Y1
Fuchs, M; Hörmann, E; Scheibner, J; Stange, EF; Tauber, G1
Fuchs, M; Hörmann, E; Scheibner, J; Schiemann, M; Stange, EF; Tauber, G1
Clarenbach, JJ; Dotti, MT; Federico, A; Kelleher, JK; Lindenthal, B; von Bergmann, K1
Cariou, B; Caron, S; Costet, P; Kourimate, S; Krempf, M; Langhi, C; Le May, C; Staels, B1
Fink, JC; Kane, MA; Karra, VK; Krug, SA; Metry, M; Polli, JE; Shu, Y; Wang, H1

Reviews

1 review(s) available for chenodeoxycholic acid and pravastatin

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Trials

1 trial(s) available for chenodeoxycholic acid and pravastatin

ArticleYear
Differential effects of metformin-mediated BSEP repression on pravastatin and bile acid pharmacokinetics in humans: A randomized controlled trial.
    Clinical and translational science, 2022, Volume: 15, Issue:10

    Topics: ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Chenodeoxycholic Acid; Humans; Metformin; Pravastatin

2022

Other Studies

9 other study(ies) available for chenodeoxycholic acid and pravastatin

ArticleYear
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
    Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Combined treatment with chenodeoxycholic acid and pravastatin improves plasma cholestanol levels associated with marked regression of tendon xanthomas in cerebrotendinous xanthomatosis.
    Metabolism: clinical and experimental, 1991, Volume: 40, Issue:7

    Topics: Adult; Anticholesteremic Agents; Bile Acids and Salts; Brain Diseases; Chenodeoxycholic Acid; Cholestanol; Cholesterol; Chromatography, High Pressure Liquid; Drug Therapy, Combination; Heptanoic Acids; Humans; Male; Muscular Diseases; Naphthalenes; Pravastatin; Tendons; Xanthomatosis

1991
Treatment of cerebrotendinous xanthomatosis: effects of chenodeoxycholic acid, pravastatin, and combined use.
    Journal of the neurological sciences, 1994, Volume: 125, Issue:1

    Topics: Adult; Apolipoproteins; Brain Diseases; Chenodeoxycholic Acid; Cholestanol; Cholesterol; Drug Therapy, Combination; Electrophysiology; Humans; Lipids; Lipoproteins; Male; Middle Aged; Muscular Diseases; Phytosterols; Pravastatin; Tendons; Xanthomatosis

1994
Biliary cholesterol secretion and bile acid formation in the hamster: the role of newly synthesized cholesterol.
    Journal of lipid research, 1994, Volume: 35, Issue:4

    Topics: Animals; Bile; Bile Acids and Salts; Chenodeoxycholic Acid; Cholesterol; Cholic Acids; Cricetinae; Female; Liver; Mesocricetus; Pravastatin

1994
Bile acid synthesis from newly synthesized vs. preformed cholesterol precursor pools in the rat.
    Hepatology (Baltimore, Md.), 1993, Volume: 17, Issue:6

    Topics: Acetates; Animals; Bile Acids and Salts; Chenodeoxycholic Acid; Cholesterol; Cholic Acid; Cholic Acids; Circadian Rhythm; Enterohepatic Circulation; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Kinetics; Male; Pravastatin; Protein Precursors; Rats; Rats, Wistar

1993
Isotopomer spectral analysis of intermediates of cholesterol synthesis in patients with cerebrotendinous xanthomatosis.
    Metabolism: clinical and experimental, 2005, Volume: 54, Issue:3

    Topics: Adult; Bile; Bile Acids and Salts; Carbon Isotopes; Chenodeoxycholic Acid; Cholestanol; Cholestanols; Cholesterol; Female; Gas Chromatography-Mass Spectrometry; Humans; Isotope Labeling; Lanosterol; Male; Middle Aged; Pravastatin; Sterols; Xanthomatosis, Cerebrotendinous

2005
Activation of the farnesoid X receptor represses PCSK9 expression in human hepatocytes.
    FEBS letters, 2008, Mar-19, Volume: 582, Issue:6

    Topics: Chenodeoxycholic Acid; DNA-Binding Proteins; Hepatocytes; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Isoxazoles; Pravastatin; Proprotein Convertase 9; Proprotein Convertases; Receptors, Cytoplasmic and Nuclear; Receptors, LDL; RNA, Messenger; Serine Endopeptidases; Transcription Factors; Transcription, Genetic

2008