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chenodeoxycholic acid and phenobarbital

chenodeoxycholic acid has been researched along with phenobarbital in 39 studies

Research

Studies (39)

Timeframe	Studies, this research(%)	All Research%
pre-1990	32 (82.05)	18.7374
1990's	0 (0.00)	18.2507
2000's	5 (12.82)	29.6817
2010's	2 (5.13)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Strassburg, CP; Tukey, RH	1
Anisfeld, AM; Edwards, PA; Goodwin, B; Jones, SA; Kast, HR; Kliewer, S; Stoltz, CM; Tarr, PT; Tontonoz, P; Willson, TM	1
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM	1
Abellán Guillén, A; Cordeiro, MN; Garrido Escudero, A; Morales Helguera, A; Pérez-Garrido, A	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Bonorris, GG; Chung, A; Coyne, MJ; Marks, JW; Schoenfield, LJ; Sherman, JH	1
Laatikainen, T	1
Paumgartner, G	1
Gregory, DH; Swell, L; Vlahcevic, ZR	1
Czygan, P; Fröhling, W; Kommerell, B; Stiehl, A	1
Tompkins, RK	1
Menghini, G; Pallotta, B	1
Hanson, RF; Isenberg, JN; Page, AR; Sharp, HL; Williams, GC; Zavoral, J	1
Bonorris, GG; Chung, A; Coyne, MJ; Goldstein, LI; Lahana, D; Schoenfield, LJ	1
Pedersen, L	1
Bloomer, JR; Boyer, JL	1
Sturdevant, RA	1
Davis, RA; Kern, F; Showalter, P	1
Bonorris, GG; Coyne, MJ; Goldstein, LI; Schoenfield, LJ	1
Björkhem, I; Gustafsson, J	1
Björkhem, I; Danielsson, H	1
Björkhem, I; Danielsson, H; Wikvall, K	1
Redinger, RN	1
Miller, NE; Nestel, PJ	1
Myant, NB	1
Smith, LL; Teng, JI; van Lier, JE	1
Cronholm, T; Einarsson, K; Gustafsson, JA	1
Bell, GD	1
Schoenfield, LJ	1
Admirand, WH; Stiehl, A; Thaler, MM	1
Boyd, GS; Percy-Robb, IW	1
Bonorris, GG; Ganz, P; Schoenfield, LJ	1
Marks, JW; Schoenfield, LJ; Zak, RA	1
Dederer, IuM	1
Bouchier, IA	1
Heikkinen, J; Jänne, O; Mäentausta, O; Ylöstalo, P	1
Hughes, E; Nottle, PD	1
Back, DJ; Martin, P; Owen, A; Riley, R	1

Reviews

11 review(s) available for chenodeoxycholic acid and phenobarbital

Article	Year
Human UDP-glucuronosyltransferases: metabolism, expression, and disease. Annual review of pharmacology and toxicology, 2000, Volume: 40 Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic	2000
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
[What is reliable in the internal therapy of the gallstone trouble?]. Der Internist, 1975, Volume: 16, Issue:12 Topics: Bile; Chenodeoxycholic Acid; Cholelithiasis; Cholesterol; Clofibrate; Diet; Dose-Response Relationship, Drug; Estrogens; Humans; Lipid Metabolism; Liver; Phenobarbital; Thyroxine	1975
Part II. The systemic treatment of gallstones. Advances in surgery, 1976, Volume: 10 Topics: Bile; Bile Acids and Salts; Chenodeoxycholic Acid; Cholagogues and Choleretics; Cholecystectomy; Cholecystography; Cholelithiasis; Cholesterol; Dose-Response Relationship, Drug; Humans; Long-Term Care; Phenobarbital; Phosphatidylcholines; Phospholipids; Postoperative Complications; Solubility	1976
[Medical treatment of gallstones]. Ugeskrift for laeger, 1975, Jul-07, Volume: 137, Issue:28 Topics: Ascorbic Acid; Chenodeoxycholic Acid; Cholelithiasis; Female; Fusidic Acid; Humans; Male; Middle Aged; Phenobarbital; Phosphatidylcholines	1975
Hydroxylations in biosynthesis and metabolism of bile acids. Molecular and cellular biochemistry, 1974, Sep-30, Volume: 4, Issue:2 Topics: Acetates; Animals; Bile Acids and Salts; Biliary Tract Diseases; Carbon Monoxide; Carbon Radioisotopes; Chenodeoxycholic Acid; Cholesterol; Cholic Acids; Cytochrome P-450 Enzyme System; Cytochrome Reductases; Electron Transport; Enzyme Activation; Hydroxylation; Hyperthyroidism; Liver; Magnesium; Microsomes, Liver; Mitochondria, Liver; Mixed Function Oxygenases; NADP; Phenobarbital; Phospholipids; Rats; Taurocholic Acid; Thyroid Hormones; Tritium	1974
Effects of drugs on the metabolism of bile acids. Advances in experimental medicine and biology, 1972, Volume: 26, Issue:0 Topics: Animals; Bile Acids and Salts; Biological Transport; Biological Transport, Active; Carbon Radioisotopes; Chenodeoxycholic Acid; Cholesterol; Cholestyramine Resin; Cholic Acids; Cytochrome c Group; Cytochrome P-450 Enzyme System; Cytochrome Reductases; Humans; Hydroxycholesterols; Ileum; Intestinal Mucosa; Liver; Liver Circulation; Mixed Function Oxygenases; Phenobarbital; Propylthiouracil; Rats; Sulfathiazoles; Taurine; Thyroid Gland; Thyroxine; Triiodothyronine; Vitamins	1972
Medical therapy for gallstones. Gastroenterology, 1974, Volume: 67, Issue:4 Topics: Administration, Oral; Bile; Bile Acids and Salts; Bilirubin; Calcium; Chemical and Drug Induced Liver Injury; Chenodeoxycholic Acid; Cholelithiasis; Cholesterol; Humans; Lithocholic Acid; Liver; Phenobarbital; United States	1974
Current status of chenodeoxycholic acid (chenodiol) therapy of cholesterol gallstones. Seminars in liver disease, 1983, Volume: 3, Issue:2 Topics: Animals; Bile Acids and Salts; Chenodeoxycholic Acid; Cholelithiasis; Cholesterol; Cholesterol, Dietary; Clinical Trials as Topic; Cricetinae; Diarrhea; Drug Therapy, Combination; Female; Haplorhini; Humans; Hydroxymethylglutaryl CoA Reductases; Intestinal Absorption; Lipids; Liver; Male; Phenobarbital; Rats; Ursodeoxycholic Acid	1983
[Dissolution of gallstones: reality and prospects]. Klinicheskaia meditsina, 1980, Volume: 58, Issue:5 Topics: Adult; Bile; Bile Acids and Salts; Chenodeoxycholic Acid; Cholelithiasis; Cholesterol; Female; Humans; Male; Micelles; Phenobarbital; Phosphatidylcholines; Pregnancy; Solubility	1980
The medical treatment of gallstones. Annual review of medicine, 1980, Volume: 31 Topics: Bile Acids and Salts; Chenodeoxycholic Acid; Cholelithiasis; Cholesterol; Cholic Acids; Gallstones; Heparin; Humans; Phenobarbital; Phospholipids; Ursodeoxycholic Acid	1980

Trials

4 trial(s) available for chenodeoxycholic acid and phenobarbital

Article	Year
Gallstone dissolution by chenodeoxycholic acid and phenobarbital. The American journal of gastroenterology, 1978, Volume: 69, Issue:2 Topics: Chenodeoxycholic Acid; Cholelithiasis; Clinical Trials as Topic; Double-Blind Method; Drug Synergism; Female; Humans; Lipid Metabolism; Male; Patient Compliance; Phenobarbital	1978
Treatment of gallstones with chenodeoxycholic acid and phenobarbital. The New England journal of medicine, 1975, Mar-20, Volume: 292, Issue:12 Topics: Adult; Aged; Bile; Biopsy; Chenodeoxycholic Acid; Cholelithiasis; Clinical Trials as Topic; Drug Therapy, Combination; Female; Humans; Lipids; Lithocholic Acid; Liver; Liver Function Tests; Male; Middle Aged; Phenobarbital	1975
Effect of chenodeoxycholic acid and phenobarbital on the rate-limiting enzymes of hepatic cholesterol and bile acid synthesis in patients with gallstones. The Journal of laboratory and clinical medicine, 1976, Volume: 87, Issue:2 Topics: Bile; Bile Acids and Salts; Chenodeoxycholic Acid; Cholelithiasis; Cholesterol; Female; Humans; Hydroxymethylglutaryl CoA Reductases; Liver; Male; Mixed Function Oxygenases; Phenobarbital; Phospholipids; Placebos	1976
Current status of chenodeoxycholic acid (chenodiol) therapy of cholesterol gallstones. Seminars in liver disease, 1983, Volume: 3, Issue:2 Topics: Animals; Bile Acids and Salts; Chenodeoxycholic Acid; Cholelithiasis; Cholesterol; Cholesterol, Dietary; Clinical Trials as Topic; Cricetinae; Diarrhea; Drug Therapy, Combination; Female; Haplorhini; Humans; Hydroxymethylglutaryl CoA Reductases; Intestinal Absorption; Lipids; Liver; Male; Phenobarbital; Rats; Ursodeoxycholic Acid	1983

Other Studies

25 other study(ies) available for chenodeoxycholic acid and phenobarbital

Article	Year
Regulation of multidrug resistance-associated protein 2 (ABCC2) by the nuclear receptors pregnane X receptor, farnesoid X-activated receptor, and constitutive androstane receptor. The Journal of biological chemistry, 2002, Jan-25, Volume: 277, Issue:4 Topics: Animals; Base Sequence; Bile Acids and Salts; Blotting, Northern; Cell Line; Cell Nucleus; Cells, Cultured; Constitutive Androstane Receptor; DNA-Binding Proteins; Drug Resistance, Multiple; Genes, Reporter; Hepatocytes; Humans; Isoxazoles; Ligands; Liver; Membrane Transport Proteins; Mice; Models, Biological; Molecular Sequence Data; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Nucleic Acid Hybridization; Phenobarbital; Pregnane X Receptor; Promoter Regions, Genetic; Protein Binding; Protein Transport; Rats; Receptors, Cytoplasmic and Nuclear; Receptors, Steroid; RNA, Messenger; Signal Transduction; Transcription Factors; Transcription, Genetic; Transcriptional Activation	2002
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2). Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11 Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship	2008
Convenient QSAR model for predicting the complexation of structurally diverse compounds with beta-cyclodextrins. Bioorganic & medicinal chemistry, 2009, Jan-15, Volume: 17, Issue:2 Topics: beta-Cyclodextrins; Hydrophobic and Hydrophilic Interactions; Organic Chemicals; Quantitative Structure-Activity Relationship	2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Effect of cholestyramine and phenobarbital on pruritus and serum bile acid levels in cholestasis of pregnancy. American journal of obstetrics and gynecology, 1978, Nov-01, Volume: 132, Issue:5 Topics: Adult; Bile Acids and Salts; Chenodeoxycholic Acid; Cholestasis; Cholestyramine Resin; Cholic Acids; Female; Humans; Phenobarbital; Pregnancy; Pregnancy Complications; Pruritus	1978
Editorial: Phenobarbital and cholesterol gallstone dissolution. The American journal of digestive diseases, 1976, Volume: 21, Issue:6 Topics: Animals; Bile Acids and Salts; Chenodeoxycholic Acid; Cholelithiasis; Cholesterol; Haplorhini; Humans; Macaca mulatta; Models, Biological; Phenobarbital	1976
Induction and activation of rat liver microsomal bile salt glucuronyltransferase. Biochimica et biophysica acta, 1976, Sep-24, Volume: 444, Issue:2 Topics: Animals; Chenodeoxycholic Acid; Cholic Acids; Enzyme Activation; Enzyme Induction; Glucuronosyltransferase; Hexosyltransferases; Lithocholic Acid; Male; Methylcholanthrene; Microsomes, Liver; Organ Size; Phenobarbital; Polyethylene Glycols; Rats	1976
Marked increase in serum levels of liver enzymes in patients receiving chenic acid and phenobarbital for gallstone dissolution. Digestion, 1976, Volume: 14, Issue:2 Topics: Alanine Transaminase; Alkaline Phosphatase; Aspartate Aminotransferases; Chenodeoxycholic Acid; Cholelithiasis; Drug Hypersensitivity; Eosinophils; Female; Humans; Liver; Liver Function Tests; Male; Middle Aged; Neutrophils; Phenobarbital; Transferases	1976
Immunodeficiency, xanthomas and obstructive liver disease. The American journal of medicine, 1976, Volume: 61, Issue:3 Topics: Bile Acids and Salts; Chenodeoxycholic Acid; Child; Cholestyramine Resin; Cholic Acids; Humans; Hypercholesterolemia; Hyperlipidemias; Immunologic Deficiency Syndromes; Liver Diseases; Male; Phenobarbital; Pruritus; Xanthomatosis	1976
Phenobarbital effects in cholestatic liver diseases. Annals of internal medicine, 1975, Volume: 82, Issue:3 Topics: Adult; Bile Ducts, Intrahepatic; Bilirubin; Chenodeoxycholic Acid; Child; Child, Preschool; Cholangitis; Cholestasis; Cholic Acids; Feces; Female; Hepatitis; Humans; Liver; Liver Cirrhosis, Biliary; Liver Function Tests; Male; Middle Aged; Phenobarbital; Pruritus; Rose Bengal; Sulfobromophthalein	1975
Medical treatment of gallstones. Southern medical journal, 1975, Volume: 68, Issue:1 Topics: Animals; Arteriosclerosis; Bile; Chenodeoxycholic Acid; Cholelithiasis; Cholestasis; Cholesterol; Diarrhea; Humans; Lipid Metabolism; Lithocholic Acid; Liver; Macaca mulatta; Phenobarbital; Phosphatidylcholines; Placebos	1975
Measurement of bile acid synthesis by 14CO2: the metabolism of propionyl CoA. Steroids, 1975, Volume: 26, Issue:4 Topics: Animals; Bile; Bile Acids and Salts; Carbon Dioxide; Catheterization; Chenodeoxycholic Acid; Cholesterol; Cholic Acids; Coenzyme A; Female; Phenobarbital; Propionates; Rats	1975
Omega-hydroxylation of steriod side-chain in biosynthesis of bile acids. European journal of biochemistry, 1973, Jul-02, Volume: 36, Issue:1 Topics: Animals; Bile Acids and Salts; Carbon Monoxide; Chenodeoxycholic Acid; Cholestanes; Cholestenes; Cholesterol; Hydroxylation; Male; Microsomes, Liver; Mitochondria, Liver; NAD; NADP; Phenobarbital; Rats; Starvation; Steroid Hydroxylases	1973
Hydroxylations of bile acids by reconstituted systems from rat liver microsomes. The Journal of biological chemistry, 1974, Oct-25, Volume: 249, Issue:20 Topics: Animals; Bile Acids and Salts; Carbon Radioisotopes; Cattle; Chenodeoxycholic Acid; Cytochrome P-450 Enzyme System; Cytochrome Reductases; Deoxycholic Acid; Drug Stability; Erythrocytes; Female; Freezing; Lithocholic Acid; Male; Microsomes, Liver; Mixed Function Oxygenases; NADP; Oxidation-Reduction; Phenobarbital; Phosphatidylcholines; Rats; Sex Factors; Superoxide Dismutase; Taurine; Time Factors; Tritium; Ultracentrifugation	1974
Pathophysiology of Cholelithiasis. Schweizerische medizinische Wochenschrift, 1974, Nov-23, Volume: 104, Issue:47 Topics: Animals; Bile; Bile Acids and Salts; Calculi; Chenodeoxycholic Acid; Cholelithiasis; Cholesterol; Cricetinae; Haplorhini; Humans; Mice; Phenobarbital; Phosphatidylcholines; Rats; Stimulation, Chemical	1974
Altered bile acid metabolism during treatment with phenobarbitone. Clinical science and molecular medicine, 1973, Volume: 45, Issue:2 Topics: Adolescent; Adult; Bile Acids and Salts; Carbon Radioisotopes; Chenodeoxycholic Acid; Cholesterol; Cholic Acids; Feces; Humans; Lipoproteins, LDL; Lipoproteins, VLDL; Male; Phenobarbital; Stimulation, Chemical; Triglycerides	1973
Sterol metabolism. XXX. Cholesterol 25-hydroperoxide metabolism. Journal of steroid biochemistry, 1974, Volume: 5, Issue:6 Topics: Animals; Bile; Cattle; Chenodeoxycholic Acid; Cholestenes; Cholesterol; Cholic Acids; Chromatography, Gas; Chromatography, Ion Exchange; Chromatography, Thin Layer; Kidney; Liver; Male; Organ Specificity; Peroxides; Phenobarbital; Rats; Species Specificity; Tritium; Ultracentrifugation	1974
Changes in in vivo metabolism of bile acids in rat after treatment with phenobarbital. Lipids, 1974, Volume: 9, Issue:11 Topics: Animals; Bile; Bile Acids and Salts; Carbon Radioisotopes; Catheterization; Chenodeoxycholic Acid; Cholic Acids; Chromatography, Gas; Deoxycholic Acid; Feces; Half-Life; Male; Mass Spectrometry; Phenobarbital; Rats; Time Factors; Tritium	1974
The present position concerning gallstone dissolution. Gut, 1974, Volume: 15, Issue:11 Topics: Animals; Bile Acids and Salts; Chenodeoxycholic Acid; Cholelithiasis; Cholesterol, Dietary; Cholestyramine Resin; Clofibrate; Humans; Phenobarbital; Phospholipids; Solvents	1974
Effects of phenobarbital on bile salt metabolism in cholestasis due to intrahepatic bile duct hypoplasia. Pediatrics, 1973, Volume: 51, Issue:6 Topics: Alkaline Phosphatase; Aspartate Aminotransferases; Bile Acids and Salts; Bile Ducts, Intrahepatic; Bilirubin; Carbon Isotopes; Chenodeoxycholic Acid; Child, Preschool; Cholestasis; Cholic Acids; Feces; Female; Half-Life; Humans; Leucyl Aminopeptidase; Liver; Phenobarbital; Pruritus	1973
The biosynthesis of bile acids. Scottish medical journal, 1973, Volume: 18, Issue:5 Topics: Bile Acids and Salts; Chenodeoxycholic Acid; Cholesterol; Cholic Acids; Enzyme Induction; Phenobarbital; Thyroid Hormones	1973
Induced alterations in the rate-limiting enzymes of hepatic cholesterol and bile acid synthesis in the hamster. The Journal of laboratory and clinical medicine, 1973, Volume: 82, Issue:6 Topics: Alcohol Oxidoreductases; Animals; Bile Acids and Salts; Chenodeoxycholic Acid; Cholesterol; Cholestyramine Resin; Cholic Acids; Cricetinae; Deoxycholic Acid; Glutarates; Hepatic Duct, Common; Liver; Male; Mevalonic Acid; Mixed Function Oxygenases; Phenobarbital	1973
Serum bile acid levels in intrahepatic cholestasis of pregnancy during treatment with phenobarbital or cholestyramine. European journal of obstetrics, gynecology, and reproductive biology, 1982, Volume: 14, Issue:3 Topics: Bile Acids and Salts; Chenodeoxycholic Acid; Cholestasis, Intrahepatic; Cholestyramine Resin; Cholic Acids; Deoxycholic Acid; Female; Humans; Liver Function Tests; Phenobarbital; Pregnancy; Pregnancy Complications; Pruritus	1982
Gallstones: operate, dissolve or leave alone? Drugs, 1981, Volume: 21, Issue:4 Topics: Butyrates; Chenodeoxycholic Acid; Cholagogues and Choleretics; Cholecystectomy; Cholelithiasis; Drug Combinations; Fluorenes; Humans; Monoterpenes; Phenobarbital; Phospholipids; Terpenes	1981
Comparison of the induction profile for drug disposition proteins by typical nuclear receptor activators in human hepatic and intestinal cells. British journal of pharmacology, 2008, Volume: 153, Issue:4 Topics: Aryl Hydrocarbon Hydroxylases; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP-Binding Cassette Transporters; Caco-2 Cells; Cell Culture Techniques; Cells, Cultured; Chenodeoxycholic Acid; Constitutive Androstane Receptor; Cytochrome P-450 CYP2B6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Dexamethasone; DNA-Binding Proteins; Dose-Response Relationship, Drug; Enzyme Induction; Epithelial Cells; Hepatocytes; Humans; Intestinal Mucosa; Membrane Transport Proteins; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Oxidoreductases, N-Demethylating; Phenobarbital; Pregnane X Receptor; Pregnenolone Carbonitrile; Receptors, Cytoplasmic and Nuclear; Receptors, Steroid; Research Design; Rifampin; RNA, Messenger; Transcription Factors; Up-Regulation	2008