chenodeoxycholic acid has been researched along with lovastatin in 15 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (6.67) | 18.7374 |
| 1990's | 8 (53.33) | 18.2507 |
| 2000's | 2 (13.33) | 29.6817 |
| 2010's | 4 (26.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Ekins, S; Williams, AJ; Xu, JJ | 1 |
| Aleo, MD; Bonin, PD; Luo, Y; Potter, DM; Swiss, R; Will, Y | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Abate, N; Bertolotti, M; Carubbi, F; Carulli, N; Digrisolo, A; Dilengite, M; Loria, P; Pinetti, A | 1 |
| De Liege, P; Gambert, P; Laurent, A; Lecoz, P; Legrand, A; Mikol, J; Peynet, J; Warnet, A | 1 |
| Duane, WC; Logan, GM; Mitchell, JC; Stone, BG | 1 |
| Carlson, TL; Kottke, BA | 1 |
| Duane, WC; Hanson, DS | 1 |
| Duane, WC | 1 |
| Batta, AK; Salen, G; Shefer, S; Tint, GS | 1 |
| Botham, KM; Hoang, VQ; Pearce, NJ; Suckling, KE | 1 |
| Bending, JJ; Leitersdorf, E; Mitchell, WD; Reshef, A; Watts, GF | 1 |
| Batta, AK; Salen, G; Tint, GS | 1 |
1 review(s) available for chenodeoxycholic acid and lovastatin
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
3 trial(s) available for chenodeoxycholic acid and lovastatin
| Article | Year |
|---|---|
Effects of lovastatin and chenodiol on bile acid synthesis, bile lipid composition, and biliary lipid secretion in healthy human subjects.
Topics: Aged; Bile; Bile Acids and Salts; Chenodeoxycholic Acid; Cholesterol; Dose-Response Relationship, Drug; Drug Combinations; Humans; Lovastatin; Male; Middle Aged; Phospholipids | 1994 |
Effects of lovastatin and dietary cholesterol on bile acid kinetics and bile lipid composition in healthy male subjects.
Topics: Absorption; Bile; Bile Acids and Salts; Chenodeoxycholic Acid; Cholesterol; Cholesterol, Dietary; Cholic Acid; Cholic Acids; Humans; Kinetics; Lipid Metabolism; Lovastatin; Male | 1994 |
Hydrophilic 7 beta-hydroxy bile acids, lovastatin, and cholestyramine are ineffective in the treatment of cerebrotendinous xanthomatosis.
Topics: Adult; Anticholesteremic Agents; Bile; Bile Acids and Salts; Case-Control Studies; Chenodeoxycholic Acid; Cholestanols; Cholesterol; Cholestyramine Resin; Cholic Acids; Homozygote; Humans; Lovastatin; Male; Middle Aged; Ursodeoxycholic Acid; Xanthomatosis, Cerebrotendinous | 2004 |
11 other study(ies) available for chenodeoxycholic acid and lovastatin
| Article | Year |
|---|---|
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
Human drug-induced liver injury severity is highly associated with dual inhibition of liver mitochondrial function and bile salt export pump.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Chemical and Drug Induced Liver Injury; Humans; Male; Mitochondria, Liver; Rats; Rats, Sprague-Dawley; Severity of Illness Index | 2014 |
Regulation of bile acid synthesis in humans: effect of treatment with bile acids, cholestyramine or simvastatin on cholesterol 7 alpha-hydroxylation rates in vivo.
Topics: Adult; Aged; Bile Acids and Salts; Chenodeoxycholic Acid; Cholesterol; Cholesterol 7-alpha-Hydroxylase; Cholestyramine Resin; Deoxycholic Acid; Dose-Response Relationship, Drug; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lovastatin; Male; Middle Aged; Simvastatin; Ursodeoxycholic Acid | 1991 |
Cerebrotendinous xanthomatosis: treatments with simvastatin, lovastatin, and chenodeoxycholic acid in 3 siblings.
Topics: Adult; Anticholesteremic Agents; Brain Diseases; Chenodeoxycholic Acid; Female; Humans; Lovastatin; Muscular Diseases; Simvastatin; Tendons; Tomography, X-Ray Computed; Xanthomatosis | 1991 |
Effects of lovastatin on biliary lipid secretion and bile acid metabolism in humans.
Topics: Adult; Aged; Bile Acids and Salts; Biliary Tract; Chenodeoxycholic Acid; Cholesterol; Cholic Acid; Cholic Acids; Humans; Lipid Metabolism; Lovastatin; Male; Middle Aged; Sitosterols | 1991 |
Effect of 25-hydroxycholesterol and bile acids on the regulation of cholesterol metabolism in Hep G2 cells.
Topics: Apolipoprotein A-I; Apolipoproteins A; Apolipoproteins E; Chenodeoxycholic Acid; Cholesterol; Humans; Hydroxycholesterols; In Vitro Techniques; Lipoproteins, LDL; Liver; Lovastatin; Receptors, LDL; RNA, Messenger; Triglycerides; Tumor Cells, Cultured | 1989 |
Comparative effects of lovastatin and chenodeoxycholic acid on plasma cholestanol levels and abnormal bile acid metabolism in cerebrotendinous xanthomatosis.
Topics: Adult; Bile; Chenodeoxycholic Acid; Cholestanol; Humans; Lovastatin; Male; Xanthomatosis | 1994 |
The regulation of bile acid synthesis in cultured hamster hepatocytes.
Topics: Animals; Bile Acids and Salts; Cells, Cultured; Chenodeoxycholic Acid; Cholestyramine Resin; Cholic Acid; Cholic Acids; Cricetinae; Hydroxycholesterols; Imidazoles; Lipoproteins, LDL; Liver; Lovastatin; Male; Mesocricetus; Mevalonic Acid; Taurocholic Acid; Urea | 1993 |
Cerebrotendinous xanthomatosis: a family study of sterol 27-hydroxylase mutations and pharmacotherapy.
Topics: Adolescent; Adult; Aged; Anticholesteremic Agents; Chenodeoxycholic Acid; Child; Child, Preschool; Cholagogues and Choleretics; Cholestanetriol 26-Monooxygenase; Cytochrome P-450 Enzyme System; England; Exons; Female; Humans; Hyperlipidemia, Familial Combined; Lovastatin; Male; Middle Aged; Musculoskeletal Diseases; Mutation; Pedigree; Simvastatin; Steroid Hydroxylases; Tendons; Xanthomatosis | 1996 |