chenodeoxycholic acid has been researched along with int-777 in 10 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (10.00) | 29.6817 |
| 2010's | 7 (70.00) | 24.3611 |
| 2020's | 2 (20.00) | 2.80 |
| Authors | Studies |
|---|---|
| Auwerx, J; Gioiello, A; Macchiarulo, A; Natalini, B; Pastorini, E; Pellicciari, R; Pruzanski, M; Roda, A; Rosatelli, E; Sardella, R; Schoonjans, K; Thomas, C | 1 |
| Adorini, L; Colliva, C; Gioiello, A; Macchiarulo, A; Nuti, R; Pellicciari, R; Pruzanski, M; Rizzo, G; Roda, A; Sabbatini, P; Venturoni, F | 1 |
| Auwerx, J; De Franco, F; Ferrari, C; Giacchè, N; Gioiello, A; Macchiarulo, A; Nuti, R; Pellicciari, R; Pols, TW; Pruzanski, M; Schoonjans, K; Thomas, C | 1 |
| Carotti, A; Colliva, C; De Franco, F; Filipponi, P; Franco, P; Gadaleta, RM; Gioiello, A; Macchiarulo, A; Moschetta, A; Mostarda, S; Passeri, D; Pellicciari, R; Roda, A | 1 |
| Adorini, L; Andersen, JB; Arbelaiz, A; Banales, JM; Bujanda, L; Caro-Maldonado, A; Carracedo, A; Erice, O; Gómez-Vallejo, V; Jimenez-Agüero, R; Labiano, I; Llop, J; Lozano, E; Marin, JJ; Martin, A; Martín-Martín, N; Marzioni, M; Munoz-Garrido, P; O'Rourke, CJ; Olaizola, P; Padro, D; Perugorria, MJ; Santos-Laso, A; Trauner, M | 1 |
| Adorini, L; D'Agati, V; Dobrinskikh, E; Dvornikov, A; Field, A; Garcia, G; Gonzalez, FJ; Gratton, E; Henriksen, K; Herman-Edelstein, M; Hill, A; Jiang, T; Kopp, JB; Krausz, KW; Levi, J; Levi, M; Lucia, S; Luo, Y; Myakala, K; Orlicky, D; Peng, Y; Pruzanski, M; Qiu, L; Ranjit, S; Rosenberg, AZ; Wang, D; Wang, XX; Xie, C | 1 |
| Hirschfield, GM; Webb, GJ | 1 |
| Bunkelman, BH; Choi, HJ; Han, M; Hu, S; Keitel, V; Kong, Y; Kwon, TH; Levi, M; Li, C; Li, S; Liu, Q; Qiu, M; Reich, M; Rosenberg, AZ; Wang, W; Xie, H; Zhao, X | 1 |
| Majee, C; Mishra, R; Sahu, R | 1 |
| Iguchi, Y; Inoue, R; Ito, K; Okumura, A; Sakamoto, K; Takeuchi, JS; Umezawa, K; Une, M; Wakita, T; Watashi, K; Yamashita, Y; Yamauchi, T; Yoneda, M | 1 |
2 review(s) available for chenodeoxycholic acid and int-777
| Article | Year |
|---|---|
Work in Progress: Drugs in Development.
Topics: Abatacept; Acetates; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antirheumatic Agents; Bezafibrate; CD40 Antigens; CD40 Ligand; Chalcones; Chemokine CX3CL1; Chenodeoxycholic Acid; Cholic Acids; Drug Development; Fenofibrate; Fibroblast Growth Factors; Humans; Hypolipidemic Agents; Immunosuppressive Agents; Janus Kinase Inhibitors; Liver Cirrhosis, Biliary; Methylamines; Peroxisome Proliferator-Activated Receptors; PPAR alpha; PPAR delta; PPAR gamma; Propionates; Pruritus; Receptors, Cytoplasmic and Nuclear; Receptors, G-Protein-Coupled; Thiazepines; Triazoles; Ustekinumab | 2018 |
An insight into primary biliary cholangitis and its recent advances in treatment: semi-synthetic analogs to combat ursodeoxycholic-acid resistance.
Topics: Animals; Bile Acids and Salts; Chenodeoxycholic Acid; Cholagogues and Choleretics; Cholic Acids; Humans; Liver Cirrhosis, Biliary; Nitrates; Ursodeoxycholic Acid | 2020 |
8 other study(ies) available for chenodeoxycholic acid and int-777
| Article | Year |
|---|---|
Discovery of 6alpha-ethyl-23(S)-methylcholic acid (S-EMCA, INT-777) as a potent and selective agonist for the TGR5 receptor, a novel target for diabesity.
Topics: Animals; Chlorocebus aethiops; CHO Cells; Cholic Acids; COS Cells; Cricetinae; Cricetulus; Diabetes Mellitus; Humans; Obesity; Rats; Receptors, G-Protein-Coupled; Stereoisomerism | 2009 |
Avicholic Acid: A Lead Compound from Birds on the Route to Potent TGR5 Modulators.
Topics: | 2012 |
Probing the Binding Site of Bile Acids in TGR5.
Topics: | 2013 |
Discovery of 3α,7α,11β-Trihydroxy-6α-ethyl-5β-cholan-24-oic Acid (TC-100), a Novel Bile Acid as Potent and Highly Selective FXR Agonist for Enterohepatic Disorders.
Topics: | 2016 |
Differential effects of FXR or TGR5 activation in cholangiocarcinoma progression.
Topics: Aged; Aged, 80 and over; Animals; Bile Acids and Salts; Bile Duct Neoplasms; Bile Ducts; Cell Line, Tumor; Cell Movement; Cell Proliferation; Chenodeoxycholic Acid; Cholangiocarcinoma; Cholic Acids; Cohort Studies; Disease Progression; Energy Metabolism; Epithelial Cells; Female; Gastrointestinal Agents; Humans; Male; Mice; Mice, Nude; Middle Aged; Mitochondria; Receptors, Cytoplasmic and Nuclear; Receptors, G-Protein-Coupled; Xenograft Model Antitumor Assays | 2018 |
FXR/TGR5 Dual Agonist Prevents Progression of Nephropathy in Diabetes and Obesity.
Topics: Albuminuria; Animals; Bile Acids and Salts; Chenodeoxycholic Acid; Cholesterol; Cholic Acids; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Disease Progression; Endoplasmic Reticulum Stress; Fibrosis; Glomerular Mesangium; Humans; Kidney Tubules; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Mitochondria; Obesity; Oxidative Stress; Podocytes; Receptors, Cytoplasmic and Nuclear; Receptors, G-Protein-Coupled; RNA, Messenger; Signal Transduction; Triglycerides | 2018 |
Bile Acid G Protein-Coupled Membrane Receptor TGR5 Modulates Aquaporin 2-Mediated Water Homeostasis.
Topics: Animals; Aquaporin 2; Bile Acids and Salts; Cells, Cultured; Chenodeoxycholic Acid; Cholic Acids; Diabetes Insipidus, Nephrogenic; Homeostasis; Kidney Tubules, Collecting; Lithocholic Acid; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Rats; Rats, Wistar; Receptors, Cytoplasmic and Nuclear; Receptors, G-Protein-Coupled; RNA, Messenger; Signal Transduction; Water | 2018 |
Dual Agonist of Farnesoid X Receptor and Takeda G Protein-Coupled Receptor 5 Inhibits Hepatitis B Virus Infection In Vitro and In Vivo.
Topics: Animals; Antiviral Agents; Bile Acids and Salts; Chenodeoxycholic Acid; Cholic Acids; Disease Models, Animal; Hep G2 Cells; Hepatitis B virus; Hepatitis B, Chronic; Humans; Male; Mice; Organic Anion Transporters, Sodium-Dependent; Prospective Studies; Receptors, Cytoplasmic and Nuclear; Receptors, G-Protein-Coupled; Symporters; Transplantation Chimera; Virus Internalization | 2021 |