Page last updated: 2024-08-21

chenodeoxycholic acid and indomethacin

chenodeoxycholic acid has been researched along with indomethacin in 15 studies

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19903 (20.00)18.7374
1990's4 (26.67)18.2507
2000's4 (26.67)29.6817
2010's4 (26.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Strassburg, CP; Tukey, RH1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Del Soldato, P; Meli, A1
Hata, Y; Hiraishi, H; Mutoh, H; Ota, S; Sugimoto, T; Terano, A; Tsukahara, H1
Erickson, RA2
Marci, M; Palleschi, M1
Hata, Y; Ivey, KJ; Kawabe, T; Ota, S; Razandi, M; Terano, A1
Moriwaki, H; Muto, Y; Nishigaki, Y; Ohnishi, H1
Fujimoto, Y; Iida, T; Yasukawa, K1

Reviews

3 review(s) available for chenodeoxycholic acid and indomethacin

ArticleYear
Human UDP-glucuronosyltransferases: metabolism, expression, and disease.
    Annual review of pharmacology and toxicology, 2000, Volume: 40

    Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic

2000
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
[Current studies of the clinical aspects and drug therapy of biliary calculosis in the elderly].
    La Clinica terapeutica, 1981, May-31, Volume: 97, Issue:4

    Topics: Age Factors; Aged; Anti-Bacterial Agents; Chenodeoxycholic Acid; Cholagogues and Choleretics; Cholelithiasis; Humans; Indomethacin; Ursodeoxycholic Acid

1981

Other Studies

12 other study(ies) available for chenodeoxycholic acid and indomethacin

ArticleYear
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
    Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Further investigations of indomethacin and intestinal ulcers in the rat.
    Toxicology, 1978, Volume: 9, Issue:1-2

    Topics: Animals; Bile; Chenodeoxycholic Acid; Eating; Female; Indomethacin; Male; Peptic Ulcer; Rats; Stomach; Time Factors

1978
Protective effect of tauroursodeoxycholate against chenodeoxycholate-induced damage to cultured rabbit gastric cells.
    Digestive diseases and sciences, 1991, Volume: 36, Issue:4

    Topics: Animals; Bile Acids and Salts; Calcium; Cells, Cultured; Chenodeoxycholic Acid; Dinoprostone; Dose-Response Relationship, Drug; Female; Free Radicals; Gastric Mucosa; Indomethacin; Isomerism; Male; Rabbits; Taurochenodeoxycholic Acid; Verapamil

1991
Intraperitoneal injection induces prostaglandin-mediated protection from bile acid intestinal mucosal injury in rats in vivo.
    Folia histochemica et cytobiologica, 1990, Volume: 28, Issue:1-2

    Topics: Animals; Chenodeoxycholic Acid; Epithelium; Indomethacin; Injections, Intraperitoneal; Intestinal Mucosa; Intestine, Small; Male; Perfusion; Prostaglandins; Rats; Rats, Inbred Strains

1990
Effect of 16,16-dimethyl PGE2 and indomethacin on bile acid-induced intestinal injury and restitution in rats.
    The Journal of laboratory and clinical medicine, 1988, Volume: 112, Issue:6

    Topics: 16,16-Dimethylprostaglandin E2; Animals; Body Water; Chenodeoxycholic Acid; Indomethacin; Intestinal Absorption; Intestinal Mucosa; Male; Mannitol; Prostaglandins E, Synthetic; Rats; Rats, Inbred Strains

1988
Bile salts stimulate mucous glycoprotein secretion from cultured rabbit gastric mucosal cells.
    The Journal of laboratory and clinical medicine, 1994, Volume: 124, Issue:3

    Topics: Animals; Bile Acids and Salts; Calcium; Cells, Cultured; Chenodeoxycholic Acid; Deoxycholic Acid; Dinoprostone; Dose-Response Relationship, Drug; Gastric Mucosa; Glycodeoxycholic Acid; Glycoproteins; Indomethacin; Male; Mucins; Rabbits; Radioimmunoassay; Taurodeoxycholic Acid; Time Factors

1994
Ursodeoxycholic acid corrects defective natural killer activity by inhibiting prostaglandin E2 production in primary biliary cirrhosis.
    Digestive diseases and sciences, 1996, Volume: 41, Issue:7

    Topics: Adult; Aged; Cells, Cultured; Chenodeoxycholic Acid; Cholic Acid; Cholic Acids; Chronic Disease; Deoxycholic Acid; Dinoprostone; Female; Hepatitis C; Humans; Indomethacin; Killer Cells, Natural; Liver Cirrhosis, Biliary; Liver Diseases; Male; Middle Aged; Ursodeoxycholic Acid

1996
Relative inhibitory activity of bile acids against 12-O-tetradecanoylphorbol-13-acetate-induced inflammation, and chenodeoxycholic acid inhibition of tumour promotion in mouse skin two-stage carcinogenesis.
    The Journal of pharmacy and pharmacology, 2009, Volume: 61, Issue:8

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anti-Inflammatory Agents; Anticarcinogenic Agents; Bile Acids and Salts; Carcinogens; Chenodeoxycholic Acid; Disease Models, Animal; Edema; Female; Indomethacin; Inflammation; Inhibitory Concentration 50; Mice; Mice, Inbred ICR; Neoplasms, Experimental; Skin Neoplasms; Structure-Activity Relationship; Tetradecanoylphorbol Acetate

2009