Page last updated: 2024-08-21

chenodeoxycholic acid and 7 alpha-hydroxy-4-cholesten-3-one

chenodeoxycholic acid has been researched along with 7 alpha-hydroxy-4-cholesten-3-one in 16 studies

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19905 (31.25)18.7374
1990's1 (6.25)18.2507
2000's1 (6.25)29.6817
2010's8 (50.00)24.3611
2020's1 (6.25)2.80

Authors

AuthorsStudies
Hanson, RF; Sherman, CA1
Axelson, M; Björkhem, I; Einarsson, K; Reihnér, E1
Björkhem, I; Kase, BF; Pedersen, JI; Strandvik, B1
Salen, G; Shefer, S; Tint, GS1
Björkhem, I; Oftebro, H; Pedersen, JI; Størmer, FC1
Danielsson, H; Gustafsson, J; Halloran, LG; Schwartz, CC; Swell, L; Vlahcevic, ZR1
Axelson, M; Einarsson, C; Hillebrant, CG1
Jirsa, M; Kovář, J; Leníček, M; Pitha, J; Vítek, L; Zimolová, M1
Burton, D; Camilleri, M; Carlson, P; Lamsam, J; McKinzie, S; Odunsi-Shiyanbade, ST; Rao, AS; Ryks, M; Singh, R; Wong, BS; Zinsmeister, AR1
Ahrens, N; Black, A; Matysik, S; Orsó, E; Schmitz, G1
Björkhem, I; Del Puppo, M; Dotti, MT; Federico, A; Gallus, GN; Magni, A; Mignarri, A1
Gillberg, PG; Graffner, H; Marschall, HU; Rikner, L1
Beuers, U; de Vries, EM; de Waart, DR; Groen, AK; Jansen, PL; Koelfat, KV; Lenicek, M; Olde Damink, SW; Ponsioen, C; Schaap, FG; Tolenaars, D; Zweers, SJ1
Borup, C; Bouchelouche, PN; Damgaard, M; Graff, J; McQuitty, C; Munck, LK; Rainteau, D; Rumessen, JJ; Wildt, S1
Al-Dury, S; Bäckhed, F; Fändriks, L; Fickert, P; Marschall, HU; Panzitt, K; Ståhlman, M; Thorell, A; Trauner, M; Wagner, M; Wahlström, A1
Camilleri, M; Vijayvargiya, P1

Reviews

1 review(s) available for chenodeoxycholic acid and 7 alpha-hydroxy-4-cholesten-3-one

ArticleYear
The Role of Bile Acids in Chronic Diarrhea.
    The American journal of gastroenterology, 2020, Volume: 115, Issue:10

    Topics: Benzothiazoles; Bile Acids and Salts; Chenodeoxycholic Acid; Cholestenones; Cholestyramine Resin; Chronic Disease; Colesevelam Hydrochloride; Colestipol; Diarrhea; Diet, Fat-Restricted; Feces; Humans; Intestinal Mucosa; Irritable Bowel Syndrome; Isoxazoles; Liver; Malabsorption Syndromes; Receptors, Cytoplasmic and Nuclear; Sequestering Agents; Taurocholic Acid

2020

Trials

5 trial(s) available for chenodeoxycholic acid and 7 alpha-hydroxy-4-cholesten-3-one

ArticleYear
Effects of treatment with deoxycholic acid and chenodeoxycholic acid on the hepatic synthesis of cholesterol and bile acids in healthy subjects.
    Hepatology (Baltimore, Md.), 2001, Volume: 33, Issue:5

    Topics: Adult; Bile Acids and Salts; Chenodeoxycholic Acid; Cholestenones; Cholesterol; Cross-Over Studies; Dehydrocholesterols; Deoxycholic Acid; Female; Humans; Lipids; Liver; Male; Middle Aged; Reference Values

2001
Regulation of diurnal variation of cholesterol 7alpha-hydroxylase (CYP7A1) activity in healthy subjects.
    Physiological research, 2010, Volume: 59, Issue:2

    Topics: Adult; Anticholesteremic Agents; Bile Acids and Salts; Blood Glucose; Chenodeoxycholic Acid; Cholestenones; Cholesterol; Cholesterol 7-alpha-Hydroxylase; Cholestyramine Resin; Circadian Rhythm; Enzyme Activation; Fatty Acids, Nonesterified; Gastrointestinal Agents; Humans; Insulin; Male; Reference Values; Triglycerides

2010
Chenodeoxycholate in females with irritable bowel syndrome-constipation: a pharmacodynamic and pharmacogenetic analysis.
    Gastroenterology, 2010, Volume: 139, Issue:5

    Topics: Administration, Oral; Adult; Bile Acids and Salts; Chenodeoxycholic Acid; Cholestenones; Chromatography, High Pressure Liquid; Delayed-Action Preparations; DNA; Dose-Response Relationship, Drug; Double-Blind Method; Enzyme-Linked Immunosorbent Assay; Female; Fibroblast Growth Factors; Follow-Up Studies; Gastrointestinal Agents; Gastrointestinal Transit; Gene Frequency; Genetic Variation; Genotype; Humans; Irritable Bowel Syndrome; Mass Spectrometry; Middle Aged; Polymorphism, Genetic; Receptor, Fibroblast Growth Factor, Type 4; Retrospective Studies; Treatment Outcome

2010
The ileal bile acid transporter inhibitor A4250 decreases serum bile acids by interrupting the enterohepatic circulation.
    Alimentary pharmacology & therapeutics, 2016, Volume: 43, Issue:2

    Topics: Adult; Bile Acids and Salts; Carrier Proteins; Chenodeoxycholic Acid; Cholestenones; Double-Blind Method; Enterohepatic Circulation; Feces; Female; Fibroblast Growth Factors; Humans; Ileum; Intestinal Mucosa; Male; Membrane Glycoproteins

2016
Obeticholic acid may increase the risk of gallstone formation in susceptible patients.
    Journal of hepatology, 2019, Volume: 71, Issue:5

    Topics: Adult; Bile Acids and Salts; Biopsy; Carrier Proteins; Chenodeoxycholic Acid; Cholestenones; Double-Blind Method; Female; Fibroblast Growth Factors; Gallbladder; Gallstones; Gene Expression; Humans; Liver; Liver Diseases; Male; Middle Aged; Receptors, Cytoplasmic and Nuclear; Treatment Outcome

2019

Other Studies

10 other study(ies) available for chenodeoxycholic acid and 7 alpha-hydroxy-4-cholesten-3-one

ArticleYear
Bile acid biosynthesis: the metabolism of 7 alpha-hydroxy-4-cholesten-3-one in the bile fistula rat.
    Steroids, 1976, Volume: 27, Issue:2

    Topics: Animals; Bile; Bile Acids and Salts; Chenodeoxycholic Acid; Cholestenes; Cholestenones; Cholesterol; Cholic Acids; Female; Rats; Time Factors

1976
The plasma level of 7 alpha-hydroxy-4-cholesten-3-one reflects the activity of hepatic cholesterol 7 alpha-hydroxylase in man.
    FEBS letters, 1991, Jun-24, Volume: 284, Issue:2

    Topics: Adult; Chenodeoxycholic Acid; Cholelithiasis; Cholestenones; Cholesterol 7-alpha-Hydroxylase; Cholestyramine Resin; Female; Humans; Liver; Male; Middle Aged; Ursodeoxycholic Acid

1991
In vivo and vitro studies on formation of bile acids in patients with Zellweger syndrome. Evidence that peroxisomes are of importance in the normal biosynthesis of both cholic and chenodeoxycholic acid.
    The Journal of clinical investigation, 1985, Volume: 76, Issue:6

    Topics: Bile Acids and Salts; Chenodeoxycholic Acid; Cholestenones; Cholic Acid; Cholic Acids; Humans; Kinetics; Liver Diseases; Metabolic Clearance Rate; Microbodies; Subcellular Fractions; Syndrome

1985
Transformation of 4-cholesten-3-one and 7 alpha-hydroxy-4-cholesten-3-one into cholestanol and bile acids in cerebrotendinous xanthomatosis.
    Gastroenterology, 1984, Volume: 87, Issue:2

    Topics: Adult; Bile Acids and Salts; Brain Diseases; Carbon Radioisotopes; Chenodeoxycholic Acid; Cholestanols; Cholestenes; Cholestenones; Cholesterol; Cholic Acid; Cholic Acids; Humans; In Vitro Techniques; Male; Microsomes, Liver; Middle Aged; Tendons; Xanthomatosis

1984
Cerebrotendinous xanthomatosis: defective liver mitochondrial hydroxylation of chenodeoxycholic acid precursors.
    Journal of lipid research, 1981, Volume: 22, Issue:4

    Topics: Adult; Brain Diseases, Metabolic; Chenodeoxycholic Acid; Cholestanol; Cholestenones; Chromatography, High Pressure Liquid; Female; Gas Chromatography-Mass Spectrometry; Humans; Hydroxycholesterols; Hydroxylation; Lipid Metabolism, Inborn Errors; Microsomes, Liver; Mitochondria, Liver; Tendinopathy; Xanthomatosis

1981
An in vivo evaluation of the quantitative significance of several potential pathways to cholic and chenodeoxycholic acids from cholesterol in man.
    Journal of lipid research, 1980, Volume: 21, Issue:4

    Topics: Bile; Chenodeoxycholic Acid; Cholestanols; Cholestenones; Cholesterol; Cholic Acids; Female; Humans; Hydroxycholesterols; Kinetics

1980
Monitoring of 7α-hydroxy-4-cholesten-3-one during therapy of cerebrotendinous xanthomatosis: a case report.
    Chemistry and physics of lipids, 2011, Volume: 164, Issue:6

    Topics: Adult; Blood Chemical Analysis; Blood Component Removal; Chenodeoxycholic Acid; Cholestenones; Follow-Up Studies; Humans; Lipoproteins, LDL; Male; Simvastatin; Treatment Outcome; Xanthomatosis, Cerebrotendinous

2011
Evaluation of cholesterol metabolism in cerebrotendinous xanthomatosis.
    Journal of inherited metabolic disease, 2016, Volume: 39, Issue:1

    Topics: Adolescent; Adult; Bile Acids and Salts; Biomarkers; Chenodeoxycholic Acid; Cholestanol; Cholestenones; Cholesterol; Disease Progression; Female; Humans; Hydroxycholesterols; Lipid Metabolism; Male; Middle Aged; Prognosis; Xanthomatosis, Cerebrotendinous; Young Adult

2016
Prolonged fibroblast growth factor 19 response in patients with primary sclerosing cholangitis after an oral chenodeoxycholic acid challenge.
    Hepatology international, 2017, Volume: 11, Issue:1

    Topics: Administration, Oral; Adult; Aged; Case-Control Studies; Cathartics; Chenodeoxycholic Acid; Cholangitis, Sclerosing; Cholestenones; Clinical Protocols; Female; Fibroblast Growth Factors; Humans; Intestinal Mucosa; Liver; Male; Middle Aged

2017
Chenodeoxycholic acid stimulated fibroblast growth factor 19 response - a potential biochemical test for bile acid diarrhoea.
    Alimentary pharmacology & therapeutics, 2017, Volume: 45, Issue:11

    Topics: Adult; Bile Acids and Salts; Case-Control Studies; Chenodeoxycholic Acid; Cholestenones; Diarrhea; Enzyme-Linked Immunosorbent Assay; Fasting; Female; Fibroblast Growth Factors; Humans; Male; Middle Aged; Pilot Projects; Prospective Studies

2017