chatancin and ketene

chatancin has been researched along with ketene* in 1 studies

Other Studies

1 other study(ies) available for chatancin and ketene

Article	Year
Short, enantioselective total synthesis of chatancin. Angewandte Chemie (International ed. in English), 2015, Jan-19, Volume: 54, Issue:4 An enantioselective total synthesis of the polycyclic diterpene (+)-chatancin, a potent PAF antagonist, is reported. Proceeding in seven steps from dihydrofarnesal, this synthetic route was designed to circumvent macrocyclization-based strategies to complex, cyclized cembranoids. The described synthesis requires only six chromatographic purifications, is high yielding, and avoids protecting-group manipulations. An X-ray crystal structure of this fragile marine natural product was obtained. Topics: Acetals; Alcohols; Crystallography, X-Ray; Cycloaddition Reaction; Diterpenes; Ethylenes; Ketones; Lewis Acids; Molecular Conformation; Oxidation-Reduction; Platelet Activating Factor; Stereoisomerism	2015

Article

Year

Short, enantioselective total synthesis of chatancin.

Angewandte Chemie (International ed. in English), 2015, Jan-19, Volume: 54, Issue:4

An enantioselective total synthesis of the polycyclic diterpene (+)-chatancin, a potent PAF antagonist, is reported. Proceeding in seven steps from dihydrofarnesal, this synthetic route was designed to circumvent macrocyclization-based strategies to complex, cyclized cembranoids. The described synthesis requires only six chromatographic purifications, is high yielding, and avoids protecting-group manipulations. An X-ray crystal structure of this fragile marine natural product was obtained.

Topics: Acetals; Alcohols; Crystallography, X-Ray; Cycloaddition Reaction; Diterpenes; Ethylenes; Ketones; Lewis Acids; Molecular Conformation; Oxidation-Reduction; Platelet Activating Factor; Stereoisomerism

2015