chaparrinone and simalikalactone-D

chaparrinone has been researched along with simalikalactone-D* in 2 studies

Other Studies

2 other study(ies) available for chaparrinone and simalikalactone-D

Article	Year
Antimalarial activity of quassinoids against chloroquine-resistant Plasmodium falciparum in vitro. The American journal of tropical medicine and hygiene, 1981, Volume: 30, Issue:3 The growth of Plasmodium falciparum in vitro was markedly inhibited by certain quassinoids (the bitter principles from plants of the family Simaroubaceae). The most active compound, simalikalactone D, gave complete inhibition at 0.005 microgram/ml. Glaucarubinone an soularubinone were equally effective at 0.006 microgram/ml, whereas chaparrinone and simarolide had little effect even at 0.01 microgram/ml. These relative activities are parallel to the antineoplastic activities of these materials. Topics: Chloroquine; Dose-Response Relationship, Drug; Drug Resistance, Microbial; Glaucarubin; Phenanthrenes; Plasmodium falciparum; Quassins	1981
Structural requirements of quassinoids for the inhibition of cell transformation. Biochemical and biophysical research communications, 1980, Apr-14, Volume: 93, Issue:3 Topics: Avian Sarcoma Viruses; Cell Transformation, Viral; DNA; DNA Replication; Dose-Response Relationship, Drug; Glaucarubin; Lactones; Leucine; Phenanthrenes; Protein Biosynthesis; Quassins; RNA; Structure-Activity Relationship	1980

Article

Year

Antimalarial activity of quassinoids against chloroquine-resistant Plasmodium falciparum in vitro.

The American journal of tropical medicine and hygiene, 1981, Volume: 30, Issue:3

The growth of Plasmodium falciparum in vitro was markedly inhibited by certain quassinoids (the bitter principles from plants of the family Simaroubaceae). The most active compound, simalikalactone D, gave complete inhibition at 0.005 microgram/ml. Glaucarubinone an soularubinone were equally effective at 0.006 microgram/ml, whereas chaparrinone and simarolide had little effect even at 0.01 microgram/ml. These relative activities are parallel to the antineoplastic activities of these materials.

Topics: Chloroquine; Dose-Response Relationship, Drug; Drug Resistance, Microbial; Glaucarubin; Phenanthrenes; Plasmodium falciparum; Quassins

1981

Structural requirements of quassinoids for the inhibition of cell transformation.

Biochemical and biophysical research communications, 1980, Apr-14, Volume: 93, Issue:3

Topics: Avian Sarcoma Viruses; Cell Transformation, Viral; DNA; DNA Replication; Dose-Response Relationship, Drug; Glaucarubin; Lactones; Leucine; Phenanthrenes; Protein Biosynthesis; Quassins; RNA; Structure-Activity Relationship

1980