Page last updated: 2024-08-18

chalcone and butein

chalcone has been researched along with butein in 35 studies

Research

Studies (35)

TimeframeStudies, this research(%)All Research%
pre-19902 (5.71)18.7374
1990's10 (28.57)18.2507
2000's18 (51.43)29.6817
2010's4 (11.43)24.3611
2020's1 (2.86)2.80

Authors

AuthorsStudies
Christensen, SB; Cruciani, G; Kharazmi, A; Liljefors, T; Nielsen, SF1
Nowakowska, Z1
Johnson, TE; Lad, R; Srinivasan, B; Xing, C1
Johnson, TE; Srinivasan, B; Xing, C1
Das, NP; Ramanathan, R; Tan, CH1
Aizu, E; Kato, R; Nakadate, T; Yamamoto, S1
Brown, S; Griffiths, LA1
Cheng, ZJ; Kuo, SC; Yu, SM1
Das, NP; Yit, CC1
Matsumoto, H; Miki, T; Nihro, Y; Satoh, T; Sogawa, S; Ueda, H1
Hayashi, K; Honda, S; Nagamatsu, T; Suzuki, Y2
Wong, KP; Zhang, K1
Cheng, LY; Mack, P; Yang, EB; Zhang, K1
Chan, SC; Cheng, ZJ; Ko, FN; Kuo, SC; Teng, CM1
Iwashita, K; Kobori, M; Tsushida, T; Yamaki, K1
Chung, HT; Kang, TH; Kim, NY; Kim, YC; Oh, GS; Pae, HO; Rhew, HY1
Chen, YZ; Guo, YJ; Mack, P; Yang, EB; Zhang, K1
Kang, HC; Kim, YC; Lee, SH; Park, EJ; Sohn, DH; Woo, SW; Zhao, YZ1
Xu, X; Zhu, L1
Kang, DG; Kim, YC; Lee, AS; Lee, HS; Lee, YM; Sohn, EJ; Yin, MH1
Chen, B; Hu, CQ; Shi, J; Sun, ZH1
Kang, TH; Kim, YC; Lee, SH; Nan, JX; Park, EJ; Seo, GS; Sohn, DH; Woo, SW; Zhao, YZ1
Chung, HT; Ji, HY; Kim, HK; Kim, YC; Lee, HI; Lee, HS; Lee, HW; Sohn, DH1
Kang, DG; Kim, YC; Lee, AS; Lee, HS; Moon, MK; Mun, YJ; Sohn, EJ; Woo, WH1
Blaut, M; Braune, A; Herles, C1
Lee, SH; Seo, GS; Sohn, DH1
Chorn, G; Samoszuk, M; Tan, J1
Chan, FL; Chen, S; Leung, LK; Wang, Y1
Geiger, PC; Han, DH; Holloszy, JO; Wright, DC1
Rosazza, JP; Sanchez-Gonzalez, M1
Jung, JW; Kim, M; Lee, T; Song, KS; Woo, JE; Yang, EJ1
Arfuso, F; Bishayee, A; Bordoloi, D; Kunnumakkara, AB; Mishra, S; Padmavathi, G; Roy, NK; Sethi, G1
Kikuchi, H; Kuribayashi, F; Madhyastha, H; Mimuro, H1
Cai, R; Chen, D; Deng, F; Li, X; Liu, J; Ren, Z; Zhang, A1

Reviews

2 review(s) available for chalcone and butein

ArticleYear
A review of anti-infective and anti-inflammatory chalcones.
    European journal of medicinal chemistry, 2007, Volume: 42, Issue:2

    Topics: Animals; Anti-Infective Agents; Anti-Inflammatory Agents; Chalcones; Structure-Activity Relationship

2007
Butein in health and disease: A comprehensive review.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2017, Feb-15, Volume: 25

    Topics: Anti-Inflammatory Agents; Antihypertensive Agents; Antineoplastic Agents, Phytogenic; Antioxidants; Chalcone; Chalcones; Humans; Neuroprotective Agents; NF-kappa B; Phytotherapy; Plant Extracts; Polyphenols; Rhus

2017

Other Studies

33 other study(ies) available for chalcone and butein

ArticleYear
Antileishmanial chalcones: statistical design, synthesis, and three-dimensional quantitative structure-activity relationship analysis.
    Journal of medicinal chemistry, 1998, Nov-19, Volume: 41, Issue:24

    Topics: Animals; Cell Division; Chalcone; Humans; In Vitro Techniques; Inhibitory Concentration 50; Leishmania donovani; Lymphocytes; Models, Molecular; Molecular Conformation; Reproducibility of Results; Structure-Activity Relationship; Trypanocidal Agents

1998
Structure-activity relationship studies of chalcone leading to 3-hydroxy-4,3',4',5'-tetramethoxychalcone and its analogues as potent nuclear factor kappaB inhibitors and their anticancer activities.
    Journal of medicinal chemistry, 2009, Nov-26, Volume: 52, Issue:22

    Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Cell Transformation, Neoplastic; Chalcone; Chalcones; Female; Genes, Reporter; Humans; I-kappa B Kinase; Inhibitory Concentration 50; Interleukin-1 Receptor-Associated Kinases; Luciferases; Lung Neoplasms; Mice; Mice, Nude; NF-kappa B; Structure-Activity Relationship; Tumor Necrosis Factor-alpha

2009
Chalcone-based inhibitors against hypoxia-inducible factor 1--structure activity relationship studies.
    Bioorganic & medicinal chemistry letters, 2011, Jan-01, Volume: 21, Issue:1

    Topics: Animals; Chalcone; Hypoxia-Inducible Factor 1; Mice; Recombinant Fusion Proteins; Structure-Activity Relationship

2011
Cytotoxic effect of plant polyphenols and fat-soluble vitamins on malignant human cultured cells.
    Cancer letters, 1992, Mar-15, Volume: 62, Issue:3

    Topics: Cell Division; Cell Survival; Chalcone; Chalcones; Diet; Flavonoids; Gallic Acid; HeLa Cells; Humans; Hydrolyzable Tannins; Lymphoma; Phenols; Plant Extracts; Polymers; Structure-Activity Relationship; Tumor Cells, Cultured; Vitamin A; Vitamins

1992
Inhibition of 12-O-tetradecanoylphorbol-13-acetate-mediated epidermal ornithine decarboxylase induction and skin tumor promotion by new lipoxygenase inhibitors lacking protein kinase C inhibitory effects.
    Carcinogenesis, 1986, Volume: 7, Issue:11

    Topics: Animals; Benzoquinones; Chalcone; Chalcones; Enzyme Induction; Female; Lipoxygenase Inhibitors; Masoprocol; Mice; Ornithine Decarboxylase; Propiophenones; Protein Kinase C; Quercetin; Quinones; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate

1986
Metabolism and excretion of butein, 2',3,4-trihydroxychalcone, 3-O-methylbutein, 4-O-methylbutein and 2',4',4-trihydroxychalcone in the rat.
    Xenobiotica; the fate of foreign compounds in biological systems, 1983, Volume: 13, Issue:11

    Topics: Administration, Oral; Animals; Bile; Chalcone; Chalcones; Dealkylation; Feces; Injections, Intraperitoneal; Injections, Intravenous; Male; Propiophenones; Rats; Rats, Inbred Strains

1983
Endothelium-dependent relaxation of rat aorta by butein, a novel cyclic AMP-specific phosphodiesterase inhibitor.
    European journal of pharmacology, 1995, Jun-23, Volume: 280, Issue:1

    Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adenylyl Cyclases; Animals; Aorta, Thoracic; Chalcone; Chalcones; Cyclic AMP; Cyclic GMP; Endothelium, Vascular; Female; Guanylate Cyclase; In Vitro Techniques; Isoenzymes; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Phenylephrine; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Rats; Rats, Wistar

1995
Cytotoxic effect of butein on human colon adenocarcinoma cell proliferation.
    Cancer letters, 1994, Jul-15, Volume: 82, Issue:1

    Topics: Adenocarcinoma; Cell Division; Chalcone; Chalcones; Colonic Neoplasms; Flavonoids; Fluorouracil; Humans; Phenols; Polymers; Polyphenols; Tumor Cells, Cultured; Uridine

1994
Protective effects of hydroxychalcones on free radical-induced cell damage.
    Biological & pharmaceutical bulletin, 1994, Volume: 17, Issue:2

    Topics: Animals; Carbon Tetrachloride; Cells, Cultured; Chalcone; Chalcones; Hemolysis; Hydrogen Peroxide; Lipid Peroxidation; Macrophages, Peritoneal; Microsomes, Liver; Rats; Rats, Wistar; Superoxides

1994
Butein ameliorates experimental anti-glomerular basement membrane (GBM) antibody-associated glomerulonephritis in rats (1).
    Japanese journal of pharmacology, 1996, Volume: 70, Issue:1

    Topics: Animals; Antibodies, Heterophile; Basement Membrane; Chalcone; Chalcones; Cholesterol; Glomerulonephritis; Immunoglobulin G; Kidney Glomerulus; Leukocytes; Male; Proteinuria; Rabbits; Rats; Rats, Sprague-Dawley

1996
Inhibition of the efflux of glutathione S-conjugates by plant polyphenols.
    Biochemical pharmacology, 1996, Nov-22, Volume: 52, Issue:10

    Topics: Adenosine Triphosphate; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport, Active; Ca(2+) Mg(2+)-ATPase; Cell Membrane; Chalcone; Chalcones; Flavonoids; Glutathione; Glutathione Transferase; Humans; Hydrolyzable Tannins; Kinetics; Phenols; Plants; Polymers; Quercetin; Tumor Cells, Cultured

1996
Butein (3,4,2',4'-tetrahydroxychalcone) ameliorates experimental anti-glomerular basement membrane antibody-associated glomerulonephritis (3).
    European journal of pharmacology, 1996, Dec-05, Volume: 316, Issue:2-3

    Topics: Animals; Cell Membrane; Chalcone; Chalcones; Dose-Response Relationship, Drug; Glomerulonephritis; Humans; Male; Phosphodiesterase Inhibitors; Rats; Rats, Sprague-Dawley; Umbilical Veins

1996
Butein, a specific protein tyrosine kinase inhibitor.
    Biochemical and biophysical research communications, 1998, Apr-17, Volume: 245, Issue:2

    Topics: Carcinoma, Hepatocellular; Chalcone; Chalcones; CSK Tyrosine-Protein Kinase; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Epidermal Growth Factor; ErbB Receptors; Flavonoids; Humans; Kinetics; Molecular Structure; Phenols; Phosphorylation; Polymers; Polyphenols; Protein Kinase C; Protein-Tyrosine Kinases; Receptor Protein-Tyrosine Kinases; src-Family Kinases; Tumor Cells, Cultured

1998
Antioxidant properties of butein isolated from Dalbergia odorifera.
    Biochimica et biophysica acta, 1998, Jun-15, Volume: 1392, Issue:2-3

    Topics: Animals; Antioxidants; Bepridil; Biphenyl Compounds; Brain; Chalcone; Chalcones; Chelating Agents; Copper; Ferrous Compounds; Free Radical Scavengers; Free Radicals; Humans; Infant; Lipid Peroxidation; Lipoproteins, LDL; Oxidation-Reduction; Peroxides; Picrates; Plants; Rats; Vitamin E

1998
Flavonoids inhibit cell growth and induce apoptosis in B16 melanoma 4A5 cells.
    Bioscience, biotechnology, and biochemistry, 2000, Volume: 64, Issue:9

    Topics: Animals; Apigenin; Apoptosis; bcl-2-Associated X Protein; bcl-X Protein; Cell Division; Chalcone; Chalcones; Flavanones; Flavonoids; Genistein; Isoflavones; Luteolin; Melanoma, Experimental; Mice; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Quercetin; Structure-Activity Relationship; Tumor Cells, Cultured

2000
Butein, a plant polyphenol, induces apoptosis concomitant with increased caspase-3 activity, decreased Bcl-2 expression and increased Bax expression in HL-60 cells.
    Pharmacology & toxicology, 2001, Volume: 88, Issue:5

    Topics: Apoptosis; bcl-2-Associated X Protein; Caspase 3; Caspases; Cell Survival; Chalcone; Chalcones; DNA Fragmentation; Dose-Response Relationship, Drug; Electrophoresis, Agar Gel; Enzyme Activation; Enzyme Precursors; Flow Cytometry; HeLa Cells; HL-60 Cells; Humans; K562 Cells; Phosphodiesterase Inhibitors; Ploidies; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Tumor Cells, Cultured; U937 Cells

2001
Inhibition of epidermal growth factor receptor tyrosine kinase by chalcone derivatives.
    Biochimica et biophysica acta, 2001, Dec-17, Volume: 1550, Issue:2

    Topics: Amino Acid Sequence; Binding Sites; Blotting, Western; Chalcone; Chalcones; Enzyme-Linked Immunosorbent Assay; Epidermal Growth Factor; ErbB Receptors; Models, Molecular; Molecular Sequence Data; Phloretin; Phosphodiesterase Inhibitors; Phosphorylation; Sequence Alignment; Structure-Activity Relationship

2001
Butein suppresses myofibroblastic differentiation of rat hepatic stellate cells in primary culture.
    The Journal of pharmacy and pharmacology, 2003, Volume: 55, Issue:3

    Topics: Actins; Animals; Antimetabolites; Blotting, Western; Bromodeoxyuridine; Cell Differentiation; Cell Survival; Cells, Cultured; Chalcone; Chalcones; Collagen; Collagenases; DNA; Fibroblasts; Liver; Male; Matrix Metalloproteinase 13; Phosphodiesterase Inhibitors; Platelet-Derived Growth Factor; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tissue Inhibitor of Metalloproteinase-1

2003
Selective separation of active inhibitors of epidermal growth factor receptor from Caragana jubata by molecularly imprinted solid-phase extraction.
    Journal of chromatography. A, 2003, Apr-04, Volume: 991, Issue:2

    Topics: Caragana; Chalcone; Chalcones; Chromatography, High Pressure Liquid; ErbB Receptors; Humans; Quercetin; Sensitivity and Specificity; Stilbenes; Tumor Cells, Cultured

2003
Hypotensive effect of butein via the inhibition of angiotensin converting enzyme.
    Biological & pharmaceutical bulletin, 2003, Volume: 26, Issue:9

    Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Aorta, Thoracic; Blood Pressure; Chalcone; Chalcones; Dose-Response Relationship, Drug; In Vitro Techniques; Isometric Contraction; Male; Muscle Contraction; Muscle Tonus; Muscle, Smooth, Vascular; Peptidyl-Dipeptidase A; Rats; Rats, Sprague-Dawley; Vasoconstrictor Agents

2003
[Studies on flavonoid constituents of Caragana intermediia].
    Yao xue xue bao = Acta pharmaceutica Sinica, 2003, Volume: 38, Issue:8

    Topics: Caragana; Chalcone; Chalcones; Drugs, Chinese Herbal; Flavanones; Flavonoids; Molecular Structure; Plants, Medicinal; Quercetin

2003
The chalcone butein from Rhus verniciflua shows antifibrogenic activity.
    Planta medica, 2003, Volume: 69, Issue:11

    Topics: Animals; Carbon Tetrachloride; Chalcone; Chalcones; Collagen Type I; DNA Primers; Dose-Response Relationship, Drug; Liver Cirrhosis, Experimental; Male; Phytotherapy; Plant Bark; Plant Extracts; Protective Agents; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; Rhus; RNA, Messenger; Tissue Inhibitor of Metalloproteinase-1

2003
Determination of butein in rat serum by high performance liquid chromatography.
    Journal of pharmaceutical and biomedical analysis, 2004, Jan-27, Volume: 34, Issue:1

    Topics: Animals; Chalcone; Chalcones; Chromatography, High Pressure Liquid; Rats; Rats, Sprague-Dawley; Reproducibility of Results

2004
Butein ameliorates renal concentrating ability in cisplatin-induced acute renal failure in rats.
    Biological & pharmaceutical bulletin, 2004, Volume: 27, Issue:3

    Topics: Acute Kidney Injury; Animals; Antineoplastic Agents; Aquaporin 2; Aquaporins; Blotting, Western; Chalcone; Chalcones; Chlorides; Cisplatin; Creatinine; Kidney Function Tests; Kidney Medulla; Male; Potassium; Rats; Rats, Sprague-Dawley; Sodium

2004
First bacterial chalcone isomerase isolated from Eubacterium ramulus.
    Archives of microbiology, 2004, Volume: 181, Issue:6

    Topics: Bromosuccinimide; Chalcone; Chalcones; Chromatography, Gel; Electrophoresis, Polyacrylamide Gel; Enzyme Inhibitors; Eubacterium; Flavanones; Flavonoids; Intramolecular Lyases; Isomerism; Molecular Weight; Phloretin; Protein Subunits; Substrate Specificity

2004
Inhibition of lipopolysaccharide-induced expression of inducible nitric oxide synthase by butein in RAW 264.7 cells.
    Biochemical and biophysical research communications, 2004, Oct-08, Volume: 323, Issue:1

    Topics: Animals; Blotting, Northern; Blotting, Western; Cell Line; Cell Nucleus; Chalcone; Chalcones; Cyclooxygenase 2; Cytosol; Dose-Response Relationship, Drug; Flow Cytometry; Inflammation; Integrin alphaVbeta3; Isoenzymes; Lipopolysaccharides; Macrophages; MAP Kinase Signaling System; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; NF-kappa B; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrites; Osteopontin; Phosphorylation; Prostaglandin-Endoperoxide Synthases; Sialoglycoproteins

2004
The chalcone butein from Rhus verniciflua Stokes inhibits clonogenic growth of human breast cancer cells co-cultured with fibroblasts.
    BMC complementary and alternative medicine, 2005, Mar-09, Volume: 5

    Topics: Aged; Breast Neoplasms; Cell Proliferation; Chalcone; Chalcones; Clone Cells; Coculture Techniques; Dose-Response Relationship, Drug; Female; Fibroblasts; Growth Inhibitors; Humans; Phytotherapy; Plant Stems; Rhus; Tumor Cells, Cultured

2005
The plant polyphenol butein inhibits testosterone-induced proliferation in breast cancer cells expressing aromatase.
    Life sciences, 2005, May-20, Volume: 77, Issue:1

    Topics: Aromatase; Aromatase Inhibitors; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Chalcone; Chalcones; Female; Flavonoids; Humans; Phenols; Polyphenols; Testosterone

2005
Are tyrosine kinases involved in mediating contraction-stimulated muscle glucose transport?
    American journal of physiology. Endocrinology and metabolism, 2006, Volume: 290, Issue:1

    Topics: Animals; Benzoquinones; Biological Transport; Chalcone; Chalcones; Deoxyglucose; Electric Stimulation; Focal Adhesion Kinase 2; Genistein; Glucose; Glucose Transporter Type 4; Hypoxia; In Vitro Techniques; Insulin; Lactams, Macrocyclic; Male; Muscle Contraction; Muscle, Skeletal; Phosphorylation; Protein-Tyrosine Kinases; Pyrimidines; Quinones; Rats; Rats, Wistar; Rifabutin; src-Family Kinases

2006
Biocatalytic synthesis of butein and sulfuretin by Aspergillus alliaceus.
    Journal of agricultural and food chemistry, 2006, Jun-28, Volume: 54, Issue:13

    Topics: Aspergillus; Benzofurans; Chalcone; Chalcones; Chromatography, High Pressure Liquid; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Enzyme Inhibitors; Flavonoids; Hydroxylation; Magnetic Resonance Spectroscopy; Oxidation-Reduction

2006
The comparison of neuroprotective effects of isoliquiritigenin and its Phase I metabolites against glutamate-induced HT22 cell death.
    Bioorganic & medicinal chemistry letters, 2016, 12-01, Volume: 26, Issue:23

    Topics: Animals; Benzofurans; Cell Death; Cell Line; Chalcone; Chalcones; Flavonoids; Glutamic Acid; Hippocampus; Mice; Neurons; Neuroprotective Agents

2016
Chalcone skeleton promotes transcription of gp91-phox gene but inhibits expression of gp91-phox protein, and hydroxyl groups in hydroxychalcones participate in the stable expression of gp91-phox protein.
    Microbiology and immunology, 2019, Volume: 63, Issue:10

    Topics: Chalcone; Chalcones; Humans; NADPH Oxidase 2; Superoxides; Tretinoin; U937 Cells

2019
Simultaneous Study of Anti-Ferroptosis and Antioxidant Mechanisms of Butein and (
    Molecules (Basel, Switzerland), 2020, Feb-05, Volume: 25, Issue:3

    Topics: Antioxidants; Bone Marrow Cells; Chalcone; Chalcones; Chromatography, High Pressure Liquid; Ferroptosis; Mesenchymal Stem Cell Transplantation; Mesenchymal Stem Cells; Molecular Structure; Neurodegenerative Diseases; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry

2020
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