chalcomoracin has been researched along with isobavachalcone* in 2 studies
2 other study(ies) available for chalcomoracin and isobavachalcone
| Article | Year |
|---|---|
[Chemical constituents from cell cultures of Morus alba].
The column chromatography on silica gel, Sephadex LH-20 and semi-preparative HPLC were used to separate and purify the compounds from the EtOAc extract of medium and MeOH extract of cell cultures of Morus alba. Eight compounds were isolated. Based on physico-chemical properties and spectroscopic data, their structures were identified as isobavachalcone (1), genistein (2), norartocarpetin (3), albanin A (4), guangsangon E (5), mulberrofuran F (6), chalcomoracin (7), kuwanon J (8). Compounds 3-6 were isolated from the cell cultures of M. alba for the first time. Topics: Benzofurans; Cell Culture Techniques; Chalcones; Chromatography, Gel; Chromatography, High Pressure Liquid; Dextrans; Genistein; Morus; Plant Leaves; Plants, Medicinal; Silica Gel; Terpenes | 2012 |
[Flavonoids from the leaves of Morus alba L].
The investigation on the leaves of Morus alba L. was carried out to find the relationship of the constituents and the pharmacological activities. The isolation and purification were performed by various chromatographies such as silica gel, Sephadex LH-20, RP-C18 column chromatography and so on. Further detailed investigation on the fraction of the ethanol extract of leaves of Morus alba yielded four Diels-Alder type adducts mulberrofuran F1 (1), mulberrofuran F (2), chalcomoracin (3), kuwanon J (4), together with two chalcones morachalcone A (5), isobavachalcone (6), and three flavones norartocarpetin (7), kuwanon C (8), 6-geranylapigenin (9). Their structures were elucidated by the spectral analysis such as NMR, MS etc. Compounds 1, 6 were isolated from this plant for the first time, compounds 4-5, 7-9 were isolated from the leaves of Morus alba L. for the first time, among which 1 was a new compound. Compounds 1-5 were evaluated for the cytotoxicity against A549, Be17402, BGC823, HCT-8 and A2780 cell lines in vitro by MTT method, but only compounds 1-3 showed cytotoxicity against several human cancer cell lines. Topics: Antineoplastic Agents, Phytogenic; Benzofurans; Cell Line, Tumor; Cell Proliferation; Chalcones; Drugs, Chinese Herbal; Flavonoids; Humans; Morus; Plant Leaves; Terpenes | 2010 |