Page last updated: 2024-09-03

cgs 26393 and endothelin-1

cgs 26393 has been researched along with endothelin-1 in 7 studies

Compound Research Comparison

Studies
(cgs 26393)
Trials
(cgs 26393)
Recent Studies (post-2010)
(cgs 26393)
Studies
(endothelin-1)
Trials
(endothelin-1)
Recent Studies (post-2010) (endothelin-1)
90012,7406323,394

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (42.86)18.2507
2000's3 (42.86)29.6817
2010's1 (14.29)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
De Lombaert, S; Jeng, AY; Kuzmich, S; Trapani, AJ1
Battistini, B; Jeng, AY; Pelletier, S; Sirois, P1
Barker, S; Mitchell, JA; Rees, GM; Walcot, NR; Warner, TD; Wood, EG; Woods, M1
Battistini, B; McKay, KO; Yap, EY1
Chang, CZ; Howng, SL; Jeng, AY; Kwan, AL; Lin, CL; Winardi, D; Yen, CP1
Goto, K1
Chai, CY; Chen, IJ; Chou, SH; Dai, ZK; Hsieh, CC; Jeng, AY; Tan, MS; Wu, BN; Wu, JR; Yeh, JL1

Reviews

1 review(s) available for cgs 26393 and endothelin-1

ArticleYear
[Prospects for endothelin-related drugs].
    Nihon rinsho. Japanese journal of clinical medicine, 2004, Volume: 62 Suppl 9

    Topics: Animals; Aspartic Acid Endopeptidases; Bosentan; Cardiovascular Diseases; Drug Design; Endothelin Receptor Antagonists; Endothelin-1; Endothelin-Converting Enzymes; Hemodynamics; Humans; Metalloendopeptidases; Organophosphonates; Peptides, Cyclic; Quinazolines; Receptors, Endothelin; Sulfonamides; Sulfonylurea Compounds; Tetracyclines; Tetrazoles

2004

Other Studies

6 other study(ies) available for cgs 26393 and endothelin-1

ArticleYear
Inhibition of big ET-1-induced pressor response by an orally active dual inhibitor of endothelin-converting enzyme and neutral endopeptidase 24.11.
    Journal of cardiovascular pharmacology, 1995, Volume: 26 Suppl 3

    Topics: Administration, Oral; Animals; Aspartic Acid Endopeptidases; Blood Pressure; Endothelin-1; Endothelin-Converting Enzymes; Endothelins; Male; Metalloendopeptidases; Neprilysin; Organophosphonates; Protease Inhibitors; Protein Precursors; Rats; Rats, Sprague-Dawley; Tetrazoles

1995
Effects of dual endothelin-converting enzyme/neutral endopeptidase inhibitors, CGS 26303 and CGS 26393, on lipopolysaccharide or interleukin-1 beta-stimulated release of endothelin from guinea pig tracheal epithelial cells.
    Journal of cardiovascular pharmacology, 1998, Volume: 31 Suppl 1

    Topics: Animals; Aspartic Acid Endopeptidases; Cells, Cultured; Endothelin-1; Endothelin-Converting Enzymes; Epithelial Cells; Guinea Pigs; Interleukin-1; Lipopolysaccharides; Male; Metalloendopeptidases; Organophosphonates; Phenylalanine; Protease Inhibitors; Tetrazoles; Trachea

1998
Endothelin-1 is induced by cytokines in human vascular smooth muscle cells: evidence for intracellular endothelin-converting enzyme.
    Molecular pharmacology, 1999, Volume: 55, Issue:5

    Topics: Aspartic Acid Endopeptidases; Cells, Cultured; Cytokines; Drug Interactions; Endothelin-1; Endothelin-Converting Enzymes; Glycopeptides; Humans; Interferon-gamma; Mammary Arteries; Metalloendopeptidases; Muscle, Smooth, Vascular; Organophosphonates; Phenylalanine; Protease Inhibitors; RNA, Messenger; Saphenous Vein; Tetrazoles; Tumor Necrosis Factor-alpha

1999
Contraction to big endothelin-1, big endothelin-2 and big endothelin-3, and endothelin-converting enzyme inhibition in human isolated bronchi.
    British journal of pharmacology, 2000, Volume: 129, Issue:1

    Topics: Aspartic Acid Endopeptidases; Bronchi; Endothelin-1; Endothelin-2; Endothelin-3; Endothelin-Converting Enzymes; Endothelins; Enzyme Inhibitors; Glycopeptides; Humans; In Vitro Techniques; Lung; Metalloendopeptidases; Organophosphonates; Protease Inhibitors; Protein Precursors; Tetrazoles

2000
Effects of endothelin-converting enzyme inhibitors on hemolysate-induced morphological changes and production of endothelin-1 in bovine cerebrovascular endothelial cells.
    Journal of cardiovascular pharmacology, 2000, Volume: 36, Issue:5 Suppl 1

    Topics: Animals; Aspartic Acid Endopeptidases; Cattle; Cells, Cultured; Cerebral Arteries; Dose-Response Relationship, Drug; Endothelin-1; Endothelin-Converting Enzymes; Endothelium, Vascular; Metalloendopeptidases; Organophosphonates; Protease Inhibitors; Tetrazoles

2000
Protective effects of a dual endothelin converting enzyme/neutral endopeptidase inhibitor on the development of pulmonary hypertension secondary to cardiac dysfunction in the rat.
    Pediatric pulmonology, 2010, Volume: 45, Issue:11

    Topics: Animals; Aspartic Acid Endopeptidases; Blood Pressure; Endothelin-1; Endothelin-Converting Enzymes; Hypertension, Pulmonary; Lung; Metalloendopeptidases; Neprilysin; Nitric Oxide Synthase Type III; Organophosphonates; Protease Inhibitors; Pulmonary Artery; Rats; Rats, Wistar; Tetrazoles; Up-Regulation

2010