cgs 26303 has been researched along with organophosphonates in 30 studies
Studies (cgs 26303) | Trials (cgs 26303) | Recent Studies (post-2010) (cgs 26303) | Studies (organophosphonates) | Trials (organophosphonates) | Recent Studies (post-2010) (organophosphonates) |
---|---|---|---|---|---|
33 | 0 | 2 | 9,968 | 880 | 3,596 |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 10 (33.33) | 18.2507 |
2000's | 18 (60.00) | 29.6817 |
2010's | 2 (6.67) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
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De Lombaert, S; Ghai, RD; Jeng, AY; Trapani, AJ; Webb, RL | 1 |
Arthur, A; Caner, HH; Jeng, AY; Kassell, NF; Kwan, AL; Lappe, RW; Lee, KS | 1 |
Held, HD; Raschak, M; Uhlig, S | 1 |
Bavbek, M; Jeng, AY; Kassell, NF; Kwan, AL; Lappe, RW; Lee, KS; Maniara, W; Toyoda, T | 1 |
Battistini, B; Jeng, AY; Pelletier, S; Sirois, P | 1 |
Bavbek, M; Jeng, AY; Kassell, NF; Kwan, AL; Lee, KS; Toyoda, T | 1 |
deWit, D; Emoto, N; Télémaque, S; Yanagisawa, M | 1 |
Hoang, MV; Sansom, CE; Turner, AJ | 1 |
Barker, S; Mitchell, JA; Rees, GM; Walcot, NR; Warner, TD; Wood, EG; Woods, M | 1 |
Carr, MJ; Goldie, RG; Henry, PJ; Jeng, AY | 1 |
Battistini, B; McKay, KO; Yap, EY | 1 |
Battistini, B; Cloutier, R; Fournier, L; Jean, S; Jeng, AY; Kavanagh, M; Kluth, D; Major, D | 1 |
Chang, CZ; Howng, SL; Jeng, AY; Kwan, AL; Lin, CL; Winardi, D; Yen, CP | 1 |
Chou, M; Feldman, DL; Jeng, AY; Mogelesky, TC | 1 |
Battistini, B; Escher, E; Jeng, AY; Pham, D; Sirois, P | 1 |
Battistini, B; Jeng, AY; Wright, JL | 1 |
Chang, CZ; Hwong, SL; Jeng, AY; Kwan, AL; Lee, KS; Lin, CL; Wu, HJ | 1 |
Allen, TJ; Burrell, LM; Cao, Z; Casley, D; Cooper, ME; Davis, BJ; Johnston, CI; Lassila, M; Tikkanen, I; Tikkanen, T | 1 |
Chang, CZ; Howng, SL; Jeng, AY; Kassell, NF; Kwan, AL; Lee, KS; Lin, CL; Savage, P; Winardi, D; Wu, SC; Yen, CP | 1 |
Barbier, S; Henry, JP; Jeng, AY; Monteil, C; Mulder, P; Renet, S; Thuillez, C | 1 |
Emoto, N | 1 |
Nakayama, Y; Tomita, K | 1 |
Goto, K | 1 |
Chang, CY; Chen, SC; Jeng, AY; Kassell, NF; Kwan, AL; Lin, TK; Lue, SI; Wu, SC; Yen, CP | 1 |
Chang, CZ; Howng, SL; Jeng, AY; Kassell, NF; Kwan, AL; Lin, TK; Winadi, D; Wu, SC; Yen, CP | 1 |
Adiarto, S; Emoto, N; Isaka, D; Jeng, AY; Masuda, S; Raharjo, SB; Yokoyama, M | 1 |
Dumont, AS; Huang, CS; Jeng, AY; Kassell, NF; Kuo, CL; Kwan, AL; Lin, CL; Liu, CS; Su, YF; Wang, CJ; Wu, SC | 1 |
Arribas-Gomez, I; Lopez-Ongil, S; Martinez-Miguel, P; Raoch, V; Rodriguez-Puyol, D; Rodriguez-Puyol, M | 1 |
Chung, CL; Kassell, NF; Kwan, AL; Lee, PY; Loh, JK; Tsai, HP; Wang, CJ; Wu, BN; Wu, SC | 1 |
Chang, LL; Cheng, KI; Chou, CW; Kwan, AL; Wang, HC | 1 |
3 review(s) available for cgs 26303 and organophosphonates
Article | Year |
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[Physiological and pathophysiological roles of the endothelin converting enzymes].
Topics: Animals; Aspartic Acid Endopeptidases; Benzazepines; Benzofurans; Drug Design; Endothelin-Converting Enzymes; Glycopeptides; Heart Failure; Humans; Hypertension; Metalloendopeptidases; Mice; Mice, Knockout; Myocardial Infarction; Organophosphonates; Phenylalanine; Tetracyclines; Tetrazoles | 2004 |
[Endothelin and kidney disease].
Topics: Animals; Aspartic Acid Endopeptidases; Autocrine Communication; Cell Division; Cyclosporine; Drug Design; Endothelin Receptor Antagonists; Endothelin-1; Endothelin-Converting Enzymes; Gene Expression; Glomerular Mesangium; Humans; Kidney Diseases; Metalloendopeptidases; Organophosphonates; Tetrazoles; Vasoconstriction | 2004 |
[Prospects for endothelin-related drugs].
Topics: Animals; Aspartic Acid Endopeptidases; Bosentan; Cardiovascular Diseases; Drug Design; Endothelin Receptor Antagonists; Endothelin-1; Endothelin-Converting Enzymes; Hemodynamics; Humans; Metalloendopeptidases; Organophosphonates; Peptides, Cyclic; Quinazolines; Receptors, Endothelin; Sulfonamides; Sulfonylurea Compounds; Tetracyclines; Tetrazoles | 2004 |
27 other study(ies) available for cgs 26303 and organophosphonates
Article | Year |
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Pharmacological profile of a non-peptidic dual inhibitor of neutral endopeptidase 24.11 and endothelin-converting enzyme.
Topics: Amino Acid Sequence; Animals; Aspartic Acid Endopeptidases; Atrial Natriuretic Factor; Blood Pressure; Cell Membrane; Endothelin-1; Endothelin-Converting Enzymes; Endothelins; Kidney Cortex; Kinetics; Male; Metalloendopeptidases; Molecular Sequence Data; Neprilysin; Oligopeptides; Organophosphonates; Phenylalanine; Protein Precursors; Rats; Rats, Inbred SHR; Substrate Specificity; Tetrazoles | 1994 |
Systemic administration of an inhibitor of endothelin-converting enzyme for attenuation of cerebral vasospasm following experimental subarachnoid hemorrhage.
Topics: Animals; Disease Models, Animal; Endothelin-1; Endothelins; Ischemic Attack, Transient; Organophosphonates; Protease Inhibitors; Protein Precursors; Rabbits; Subarachnoid Hemorrhage; Tetrazoles; Time Factors | 1996 |
Rat big endothelin-1-induced bronchoconstriction and vasoconstriction in the isolated perfused rat lung: role of endothelin converting enzyme and neutral endopeptidase 24.11.
Topics: Airway Resistance; Analysis of Variance; Animals; Aspartic Acid Endopeptidases; Bronchoconstriction; Endothelin-1; Endothelin-Converting Enzymes; Endothelins; Female; Glycopeptides; Lung; Metalloendopeptidases; Neprilysin; Organophosphonates; Perfusion; Protease Inhibitors; Protein Precursors; Rats; Rats, Wistar; Tetrazoles; Thiorphan; Vascular Resistance; Vasoconstriction | 1997 |
Prevention and reversal of cerebral vasospasm by an endothelin-converting enzyme inhibitor, CGS 26303, in an experimental model of subarachnoid hemorrhage.
Topics: Animals; Disease Models, Animal; Ischemic Attack, Transient; Male; Organophosphonates; Protease Inhibitors; Rabbits; Subarachnoid Hemorrhage; Tetrazoles | 1997 |
Effects of dual endothelin-converting enzyme/neutral endopeptidase inhibitors, CGS 26303 and CGS 26393, on lipopolysaccharide or interleukin-1 beta-stimulated release of endothelin from guinea pig tracheal epithelial cells.
Topics: Animals; Aspartic Acid Endopeptidases; Cells, Cultured; Endothelin-1; Endothelin-Converting Enzymes; Epithelial Cells; Guinea Pigs; Interleukin-1; Lipopolysaccharides; Male; Metalloendopeptidases; Organophosphonates; Phenylalanine; Protease Inhibitors; Tetrazoles; Trachea | 1998 |
Attenuation of experimental subarachnoid hemorrhage-induced cerebral vasospasm by CGS 26303, an endothelin-converting enzyme inhibitor.
Topics: Animals; Aspartic Acid Endopeptidases; Dose-Response Relationship, Drug; Endothelin-Converting Enzymes; Ischemic Attack, Transient; Metalloendopeptidases; Organophosphonates; Protease Inhibitors; Rabbits; Subarachnoid Hemorrhage; Tetrazoles | 1998 |
In vivo role of endothelin-converting enzyme-1 as examined by adenovirus-mediated overexpression in rats.
Topics: Adenoviridae Infections; Animals; Aspartic Acid Endopeptidases; Azepines; Blood Pressure; Cattle; DNA, Complementary; Endothelin Receptor Antagonists; Endothelin-1; Endothelin-Converting Enzymes; Endothelins; Humans; Hypertension; Indoles; Male; Metalloendopeptidases; Organophosphonates; Protease Inhibitors; Protein Precursors; Rats; Rats, Wistar; Receptor, Endothelin A; Tetrazoles | 1998 |
Molecular modelling and site-directed mutagenesis of the active site of endothelin-converting enzyme.
Topics: Amino Acid Sequence; Animals; Aspartic Acid Endopeptidases; Binding Sites; CHO Cells; Conserved Sequence; Cricetinae; Endothelin-Converting Enzymes; Gene Expression; Glycopeptides; Humans; Metalloendopeptidases; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Neprilysin; Organophosphonates; Protease Inhibitors; Rats; Recombinant Proteins; Sequence Alignment; Tetrazoles; Thermolysin | 1998 |
Endothelin-1 is induced by cytokines in human vascular smooth muscle cells: evidence for intracellular endothelin-converting enzyme.
Topics: Aspartic Acid Endopeptidases; Cells, Cultured; Cytokines; Drug Interactions; Endothelin-1; Endothelin-Converting Enzymes; Glycopeptides; Humans; Interferon-gamma; Mammary Arteries; Metalloendopeptidases; Muscle, Smooth, Vascular; Organophosphonates; Phenylalanine; Protease Inhibitors; RNA, Messenger; Saphenous Vein; Tetrazoles; Tumor Necrosis Factor-alpha | 1999 |
The role of endothelin in mediating virus-induced changes in endothelinB receptor density in mouse airways.
Topics: Animals; Autoradiography; Disease Models, Animal; Down-Regulation; Endothelin-1; Influenza A virus; Lung; Male; Mice; Mice, Inbred CBA; Muscle, Smooth; Neprilysin; Organ Size; Organophosphonates; Orthomyxoviridae Infections; Protease Inhibitors; Receptor, Endothelin B; Receptors, Endothelin; Tetrazoles; Trachea | 1999 |
Contraction to big endothelin-1, big endothelin-2 and big endothelin-3, and endothelin-converting enzyme inhibition in human isolated bronchi.
Topics: Aspartic Acid Endopeptidases; Bronchi; Endothelin-1; Endothelin-2; Endothelin-3; Endothelin-Converting Enzymes; Endothelins; Enzyme Inhibitors; Glycopeptides; Humans; In Vitro Techniques; Lung; Metalloendopeptidases; Organophosphonates; Protease Inhibitors; Protein Precursors; Tetrazoles | 2000 |
Effect of CGS 26303, an endothelin-converting enzyme-neutral endopeptidase inhibitor, on nitrofen-induced congenital diaphragmatic hernia in the rat.
Topics: Animals; Animals, Newborn; Aspartic Acid Endopeptidases; Body Weight; Disease Models, Animal; Endothelin-Converting Enzymes; Female; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Injections, Subcutaneous; Linear Models; Liver; Lung; Metalloendopeptidases; Organ Size; Organophosphonates; Phenyl Ethers; Pregnancy; Proportional Hazards Models; Protease Inhibitors; Rats; Reference Values; Survival Analysis; Tetrazoles | 2000 |
Effects of endothelin-converting enzyme inhibitors on hemolysate-induced morphological changes and production of endothelin-1 in bovine cerebrovascular endothelial cells.
Topics: Animals; Aspartic Acid Endopeptidases; Cattle; Cells, Cultured; Cerebral Arteries; Dose-Response Relationship, Drug; Endothelin-1; Endothelin-Converting Enzymes; Endothelium, Vascular; Metalloendopeptidases; Organophosphonates; Protease Inhibitors; Tetrazoles | 2000 |
Attenuation of puromycin aminonucleoside-induced glomerular lesions in rats by CGS 26303, a dual neutral endopeptidase/endothelin-converting enzyme inhibitor.
Topics: Animals; Aspartic Acid Endopeptidases; Blotting, Northern; Endothelin-Converting Enzymes; Kidney Glomerulus; Male; Metalloendopeptidases; Neprilysin; Organophosphonates; Protease Inhibitors; Proteinuria; Puromycin Aminonucleoside; Rats; Rats, Sprague-Dawley; Receptors, Endothelin; RNA, Messenger; Tetrazoles | 2000 |
Effects of a selective neutral endopeptidase and a nonselective neutral endopeptidase/endothelin-converting enzyme inhibitor on lipopolysaccharide-induced endotoxaemia in anaesthetized Sprague-Dawley rats.
Topics: Acid-Base Equilibrium; Animals; Aspartic Acid Endopeptidases; Blood Cell Count; Endothelin-Converting Enzymes; Endotoxemia; Hemodynamics; Lipopolysaccharides; Male; Metalloendopeptidases; Neprilysin; Organophosphonates; Phenylalanine; Protease Inhibitors; Rats; Rats, Sprague-Dawley; Tetrazoles | 2000 |
Effect of ECE and NEP inhibition on cigarette smoke-induced cell proliferation in the rat lung.
Topics: Administration, Inhalation; Animals; Bromodeoxyuridine; Bronchi; Cell Division; Drug Interactions; Endothelium, Vascular; Glycopeptides; Male; Metalloendopeptidases; Neprilysin; Organophosphonates; Phenylalanine; Protease Inhibitors; Pulmonary Alveoli; Pulmonary Artery; Rats; Rats, Sprague-Dawley; Respiratory Mucosa; Smoking; Tetrazoles | 2001 |
Continuous intravenous infusion of CGS 26303, an endothelin-converting enzyme inhibitor, prevents and reverses cerebral vasospasm after experimental subarachnoid hemorrhage.
Topics: Animals; Aspartic Acid Endopeptidases; Endothelin-Converting Enzymes; Infusions, Intravenous; Male; Metalloendopeptidases; Organophosphonates; Protease Inhibitors; Rabbits; Subarachnoid Hemorrhage; Tetrazoles; Vasospasm, Intracranial | 2001 |
Combined inhibition of neutral endopeptidase with angiotensin converting enzyme or endothelin converting enzyme in experimental diabetes.
Topics: Albuminuria; Angiotensin-Converting Enzyme Inhibitors; Animals; Aspartic Acid Endopeptidases; Atrial Natriuretic Factor; Blood Pressure; Bosentan; Diabetes Mellitus, Experimental; Drug Interactions; Endothelin Receptor Antagonists; Endothelin-Converting Enzymes; Heart; Kidney; Male; Metalloendopeptidases; Myocardium; Neprilysin; Organ Size; Organophosphonates; Protease Inhibitors; Rats; Rats, Sprague-Dawley; Renin; Sulfonamides; Tetrazoles | 2002 |
Oral administration of an inhibitor of endothelin-converting enzyme attenuates cerebral vasospasm following experimental subarachnoid haemorrhage in rabbits.
Topics: Administration, Oral; Animals; Aspartic Acid Endopeptidases; Basilar Artery; Dose-Response Relationship, Drug; Endothelin-Converting Enzymes; Enzyme Inhibitors; Metalloendopeptidases; Organophosphonates; Rabbits; Subarachnoid Hemorrhage; Tetrazoles; Vasospasm, Intracranial | 2002 |
Sustained improvement of cardiac function and prevention of cardiac remodeling after long-term dual ECE-NEP inhibition in rats with congestive heart failure.
Topics: Animals; Aspartic Acid Endopeptidases; Blood Pressure; Cardiac Output; Endothelin-Converting Enzymes; Heart Failure; Heart Rate; Male; Metalloendopeptidases; Neprilysin; Organophosphonates; Phenylalanine; Rats; Rats, Wistar; Tetrazoles; Ventricular Remodeling | 2004 |
CGS 26303 upregulates mRNA expression of heme oxygenase-1 in brain tissue of rats subjected to experimental subarachnoid hemorrhage.
Topics: Animals; Aspartic Acid Endopeptidases; Brain; Disease Models, Animal; Endothelin-Converting Enzymes; Gene Expression Regulation, Enzymologic; Heme Oxygenase (Decyclizing); HSP70 Heat-Shock Proteins; Male; Metalloendopeptidases; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Organophosphonates; Protease Inhibitors; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Subarachnoid Hemorrhage; Tetrazoles; Up-Regulation; Vasospasm, Intracranial | 2004 |
Neuroprotective effect of CGS 26303, an endothelin-converting enzyme inhibitor, on transient middle cerebral artery occlusion in rats.
Topics: Animals; Aspartic Acid Endopeptidases; Behavior, Animal; Brain; Brain Edema; Disease Models, Animal; Drug Administration Schedule; Endothelin-Converting Enzymes; Infarction, Middle Cerebral Artery; Injections, Intravenous; Male; Metalloendopeptidases; Neuroprotective Agents; Organophosphonates; Protease Inhibitors; Rats; Rats, Sprague-Dawley; Tetrazoles | 2004 |
Dual ECE/NEP inhibition on cardiac and neurohumoral function during the transition from hypertrophy to heart failure in rats.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Aspartic Acid Endopeptidases; Atrial Natriuretic Factor; Cardiac Output, Low; Cardiomegaly; Collagen; Echocardiography; Endothelin-1; Endothelin-Converting Enzymes; Enzyme Inhibitors; Fibrosis; Heart; Male; Metalloendopeptidases; Myocardium; Neprilysin; Neurotransmitter Agents; Organophosphonates; Phenylalanine; Rats; Rats, Inbred Dahl; RNA, Messenger; Tetrazoles; Thiazepines | 2005 |
Attenuation of experimental subarachnoid hemorrhage-induced increases in circulating intercellular adhesion molecule-1 and cerebral vasospasm by the endothelin-converting enzyme inhibitor CGS 26303.
Topics: Animals; Aspartic Acid Endopeptidases; Disease Models, Animal; E-Selectin; Endothelin-Converting Enzymes; Intercellular Adhesion Molecule-1; Male; Metalloendopeptidases; Organophosphonates; Rabbits; Subarachnoid Hemorrhage; Tetrazoles; Vascular Cell Adhesion Molecule-1; Vasospasm, Intracranial | 2007 |
The peptidase inhibitor CGS-26303 increases endothelin converting enzyme-1 expression in endothelial cells through accumulation of big endothelin-1.
Topics: Animals; Aorta, Thoracic; Aspartic Acid Endopeptidases; Blotting, Northern; Blotting, Western; Cattle; Cells, Cultured; Dose-Response Relationship, Drug; Endothelin-1; Endothelin-Converting Enzymes; Endothelium, Vascular; Enzyme-Linked Immunosorbent Assay; Gene Expression Regulation; Humans; Metalloendopeptidases; Methyltransferases; Neprilysin; Organophosphonates; Promoter Regions, Genetic; Protease Inhibitors; Tetrazoles; Transfection | 2007 |
Alteration of basilar artery rho-kinase and soluble guanylyl cyclase protein expression in a rat model of cerebral vasospasm following subarachnoid hemorrhage.
Topics: Animals; Basilar Artery; Behavior, Animal; Cyclic AMP; Cyclic GMP-Dependent Protein Kinases; Disease Models, Animal; Endothelin-1; Guanylate Cyclase; Male; Organ Specificity; Organophosphonates; Protein Kinase C-delta; Protein Kinase Inhibitors; Protein Transport; Rats, Sprague-Dawley; Receptors, Cytoplasmic and Nuclear; rho-Associated Kinases; Signal Transduction; Soluble Guanylyl Cyclase; Subarachnoid Hemorrhage; Tetrazoles; Vasospasm, Intracranial | 2014 |
Intrathecal CGS-26303 Pretreatment Attenuates Spinal Nerve Ligation-Induced Neuropathic Pain in the Spinal Cord.
Topics: Analgesics; Animals; Down-Regulation; Injections, Spinal; Ligation; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Neuralgia; Organophosphonates; Rats, Sprague-Dawley; Spinal Nerves; Tetrazoles | 2016 |