cgs 26303 has been researched along with endothelin-1 in 14 studies
| Studies (cgs 26303) | Trials (cgs 26303) | Recent Studies (post-2010) (cgs 26303) | Studies (endothelin-1) | Trials (endothelin-1) | Recent Studies (post-2010) (endothelin-1) |
|---|---|---|---|---|---|
| 33 | 0 | 2 | 12,740 | 632 | 3,394 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 7 (50.00) | 18.2507 |
| 2000's | 6 (42.86) | 29.6817 |
| 2010's | 1 (7.14) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| De Lombaert, S; Ghai, RD; Jeng, AY; Trapani, AJ; Webb, RL | 1 |
| Arthur, A; Caner, HH; Jeng, AY; Kassell, NF; Kwan, AL; Lappe, RW; Lee, KS | 1 |
| Held, HD; Raschak, M; Uhlig, S | 1 |
| Battistini, B; Jeng, AY; Pelletier, S; Sirois, P | 1 |
| deWit, D; Emoto, N; Télémaque, S; Yanagisawa, M | 1 |
| Barker, S; Mitchell, JA; Rees, GM; Walcot, NR; Warner, TD; Wood, EG; Woods, M | 1 |
| Carr, MJ; Goldie, RG; Henry, PJ; Jeng, AY | 1 |
| Battistini, B; McKay, KO; Yap, EY | 1 |
| Chang, CZ; Howng, SL; Jeng, AY; Kwan, AL; Lin, CL; Winardi, D; Yen, CP | 1 |
| Nakayama, Y; Tomita, K | 1 |
| Goto, K | 1 |
| Adiarto, S; Emoto, N; Isaka, D; Jeng, AY; Masuda, S; Raharjo, SB; Yokoyama, M | 1 |
| Arribas-Gomez, I; Lopez-Ongil, S; Martinez-Miguel, P; Raoch, V; Rodriguez-Puyol, D; Rodriguez-Puyol, M | 1 |
| Chung, CL; Kassell, NF; Kwan, AL; Lee, PY; Loh, JK; Tsai, HP; Wang, CJ; Wu, BN; Wu, SC | 1 |
2 review(s) available for cgs 26303 and endothelin-1
| Article | Year |
|---|---|
[Endothelin and kidney disease].
Topics: Animals; Aspartic Acid Endopeptidases; Autocrine Communication; Cell Division; Cyclosporine; Drug Design; Endothelin Receptor Antagonists; Endothelin-1; Endothelin-Converting Enzymes; Gene Expression; Glomerular Mesangium; Humans; Kidney Diseases; Metalloendopeptidases; Organophosphonates; Tetrazoles; Vasoconstriction | 2004 |
[Prospects for endothelin-related drugs].
Topics: Animals; Aspartic Acid Endopeptidases; Bosentan; Cardiovascular Diseases; Drug Design; Endothelin Receptor Antagonists; Endothelin-1; Endothelin-Converting Enzymes; Hemodynamics; Humans; Metalloendopeptidases; Organophosphonates; Peptides, Cyclic; Quinazolines; Receptors, Endothelin; Sulfonamides; Sulfonylurea Compounds; Tetracyclines; Tetrazoles | 2004 |
12 other study(ies) available for cgs 26303 and endothelin-1
| Article | Year |
|---|---|
Pharmacological profile of a non-peptidic dual inhibitor of neutral endopeptidase 24.11 and endothelin-converting enzyme.
Topics: Amino Acid Sequence; Animals; Aspartic Acid Endopeptidases; Atrial Natriuretic Factor; Blood Pressure; Cell Membrane; Endothelin-1; Endothelin-Converting Enzymes; Endothelins; Kidney Cortex; Kinetics; Male; Metalloendopeptidases; Molecular Sequence Data; Neprilysin; Oligopeptides; Organophosphonates; Phenylalanine; Protein Precursors; Rats; Rats, Inbred SHR; Substrate Specificity; Tetrazoles | 1994 |
Systemic administration of an inhibitor of endothelin-converting enzyme for attenuation of cerebral vasospasm following experimental subarachnoid hemorrhage.
Topics: Animals; Disease Models, Animal; Endothelin-1; Endothelins; Ischemic Attack, Transient; Organophosphonates; Protease Inhibitors; Protein Precursors; Rabbits; Subarachnoid Hemorrhage; Tetrazoles; Time Factors | 1996 |
Rat big endothelin-1-induced bronchoconstriction and vasoconstriction in the isolated perfused rat lung: role of endothelin converting enzyme and neutral endopeptidase 24.11.
Topics: Airway Resistance; Analysis of Variance; Animals; Aspartic Acid Endopeptidases; Bronchoconstriction; Endothelin-1; Endothelin-Converting Enzymes; Endothelins; Female; Glycopeptides; Lung; Metalloendopeptidases; Neprilysin; Organophosphonates; Perfusion; Protease Inhibitors; Protein Precursors; Rats; Rats, Wistar; Tetrazoles; Thiorphan; Vascular Resistance; Vasoconstriction | 1997 |
Effects of dual endothelin-converting enzyme/neutral endopeptidase inhibitors, CGS 26303 and CGS 26393, on lipopolysaccharide or interleukin-1 beta-stimulated release of endothelin from guinea pig tracheal epithelial cells.
Topics: Animals; Aspartic Acid Endopeptidases; Cells, Cultured; Endothelin-1; Endothelin-Converting Enzymes; Epithelial Cells; Guinea Pigs; Interleukin-1; Lipopolysaccharides; Male; Metalloendopeptidases; Organophosphonates; Phenylalanine; Protease Inhibitors; Tetrazoles; Trachea | 1998 |
In vivo role of endothelin-converting enzyme-1 as examined by adenovirus-mediated overexpression in rats.
Topics: Adenoviridae Infections; Animals; Aspartic Acid Endopeptidases; Azepines; Blood Pressure; Cattle; DNA, Complementary; Endothelin Receptor Antagonists; Endothelin-1; Endothelin-Converting Enzymes; Endothelins; Humans; Hypertension; Indoles; Male; Metalloendopeptidases; Organophosphonates; Protease Inhibitors; Protein Precursors; Rats; Rats, Wistar; Receptor, Endothelin A; Tetrazoles | 1998 |
Endothelin-1 is induced by cytokines in human vascular smooth muscle cells: evidence for intracellular endothelin-converting enzyme.
Topics: Aspartic Acid Endopeptidases; Cells, Cultured; Cytokines; Drug Interactions; Endothelin-1; Endothelin-Converting Enzymes; Glycopeptides; Humans; Interferon-gamma; Mammary Arteries; Metalloendopeptidases; Muscle, Smooth, Vascular; Organophosphonates; Phenylalanine; Protease Inhibitors; RNA, Messenger; Saphenous Vein; Tetrazoles; Tumor Necrosis Factor-alpha | 1999 |
The role of endothelin in mediating virus-induced changes in endothelinB receptor density in mouse airways.
Topics: Animals; Autoradiography; Disease Models, Animal; Down-Regulation; Endothelin-1; Influenza A virus; Lung; Male; Mice; Mice, Inbred CBA; Muscle, Smooth; Neprilysin; Organ Size; Organophosphonates; Orthomyxoviridae Infections; Protease Inhibitors; Receptor, Endothelin B; Receptors, Endothelin; Tetrazoles; Trachea | 1999 |
Contraction to big endothelin-1, big endothelin-2 and big endothelin-3, and endothelin-converting enzyme inhibition in human isolated bronchi.
Topics: Aspartic Acid Endopeptidases; Bronchi; Endothelin-1; Endothelin-2; Endothelin-3; Endothelin-Converting Enzymes; Endothelins; Enzyme Inhibitors; Glycopeptides; Humans; In Vitro Techniques; Lung; Metalloendopeptidases; Organophosphonates; Protease Inhibitors; Protein Precursors; Tetrazoles | 2000 |
Effects of endothelin-converting enzyme inhibitors on hemolysate-induced morphological changes and production of endothelin-1 in bovine cerebrovascular endothelial cells.
Topics: Animals; Aspartic Acid Endopeptidases; Cattle; Cells, Cultured; Cerebral Arteries; Dose-Response Relationship, Drug; Endothelin-1; Endothelin-Converting Enzymes; Endothelium, Vascular; Metalloendopeptidases; Organophosphonates; Protease Inhibitors; Tetrazoles | 2000 |
Dual ECE/NEP inhibition on cardiac and neurohumoral function during the transition from hypertrophy to heart failure in rats.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Aspartic Acid Endopeptidases; Atrial Natriuretic Factor; Cardiac Output, Low; Cardiomegaly; Collagen; Echocardiography; Endothelin-1; Endothelin-Converting Enzymes; Enzyme Inhibitors; Fibrosis; Heart; Male; Metalloendopeptidases; Myocardium; Neprilysin; Neurotransmitter Agents; Organophosphonates; Phenylalanine; Rats; Rats, Inbred Dahl; RNA, Messenger; Tetrazoles; Thiazepines | 2005 |
The peptidase inhibitor CGS-26303 increases endothelin converting enzyme-1 expression in endothelial cells through accumulation of big endothelin-1.
Topics: Animals; Aorta, Thoracic; Aspartic Acid Endopeptidases; Blotting, Northern; Blotting, Western; Cattle; Cells, Cultured; Dose-Response Relationship, Drug; Endothelin-1; Endothelin-Converting Enzymes; Endothelium, Vascular; Enzyme-Linked Immunosorbent Assay; Gene Expression Regulation; Humans; Metalloendopeptidases; Methyltransferases; Neprilysin; Organophosphonates; Promoter Regions, Genetic; Protease Inhibitors; Tetrazoles; Transfection | 2007 |
Alteration of basilar artery rho-kinase and soluble guanylyl cyclase protein expression in a rat model of cerebral vasospasm following subarachnoid hemorrhage.
Topics: Animals; Basilar Artery; Behavior, Animal; Cyclic AMP; Cyclic GMP-Dependent Protein Kinases; Disease Models, Animal; Endothelin-1; Guanylate Cyclase; Male; Organ Specificity; Organophosphonates; Protein Kinase C-delta; Protein Kinase Inhibitors; Protein Transport; Rats, Sprague-Dawley; Receptors, Cytoplasmic and Nuclear; rho-Associated Kinases; Signal Transduction; Soluble Guanylyl Cyclase; Subarachnoid Hemorrhage; Tetrazoles; Vasospasm, Intracranial | 2014 |