cgs 25462 has been researched along with omapatrilat in 3 studies
| Studies (cgs 25462) | Trials (cgs 25462) | Recent Studies (post-2010) (cgs 25462) | Studies (omapatrilat) | Trials (omapatrilat) | Recent Studies (post-2010) (omapatrilat) |
|---|---|---|---|---|---|
| 7 | 0 | 0 | 226 | 33 | 22 |
| Protein | Taxonomy | cgs 25462 (IC50) | omapatrilat (IC50) |
|---|---|---|---|
| Amyloid-beta precursor protein | Homo sapiens (human) | 0.1995 | |
| Neprilysin | Rattus norvegicus (Norway rat) | 0.0083 | |
| Neprilysin | Homo sapiens (human) | 0.0002 | |
| Angiotensin-converting enzyme | Homo sapiens (human) | 0.001 | |
| Angiotensin-converting enzyme | Oryctolagus cuniculus (rabbit) | 0.0053 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Pu, Q; Schiffrin, EL; Touyz, RM | 1 |
| Perlini, S | 1 |
| Amiri, F; Gannon, P; Pu, Q; Schiffrin, EL | 1 |
3 other study(ies) available for cgs 25462 and omapatrilat
| Article | Year |
|---|---|
Comparison of angiotensin-converting enzyme (ACE), neutral endopeptidase (NEP) and dual ACE/NEP inhibition on blood pressure and resistance arteries of deoxycorticosterone acetate-salt hypertensive rats.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Biphenyl Compounds; Blood Pressure; Collagen; Desoxycorticosterone; Drug Therapy, Combination; Endothelium, Vascular; Enzyme Inhibitors; Hypertension; Male; Mesenteric Arteries; Myocardium; Neprilysin; Organ Size; Organophosphonates; Pyridines; Rats; Rats, Sprague-Dawley; Sodium Chloride; Systole; Thiazepines; Vascular Resistance | 2002 |
The potential advantage of omapatrilat: dual anti-fibrotic and anti-inflammatory effects in one single molecule.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Biphenyl Compounds; Cell Adhesion Molecules; Desoxycorticosterone; Drug Therapy, Combination; Fibrosis; Heart Diseases; Hypertension; Inflammation; Kidney Diseases; Metalloendopeptidases; Neprilysin; Organophosphonates; Pyridines; Rats; Thiazepines | 2005 |
Dual angiotensin-converting enzyme/neutral endopeptidase inhibition on cardiac and renal fibrosis and inflammation in DOCA-salt hypertensive rats.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Biphenyl Compounds; Blood Pressure; Cell Adhesion Molecules; Collagen; Desoxycorticosterone; Drug Therapy, Combination; Enalapril; Fibrosis; Heart Diseases; Hypertension; Inflammation; Kidney Diseases; Metalloendopeptidases; Neprilysin; NF-kappa B; Organophosphonates; Pyridines; Rats; Rats, Sprague-Dawley; Thiazepines | 2005 |