Compounds > cgp 47645
Page last updated: 2024-09-03

cgp 47645 and letrozole

cgp 47645 has been researched along with letrozole in 4 studies

Compound Research Comparison

Studies
(cgp 47645)		Trials
(cgp 47645)		Recent Studies (post-2010)
(cgp 47645)		Studies
(letrozole)		Trials
(letrozole)		Recent Studies (post-2010) (letrozole)
8122,6126121,602

Protein Interaction Comparison

ProteinTaxonomycgp 47645 (IC50)letrozole (IC50)
Steryl-sulfataseHomo sapiens (human)0.0009
AromataseHomo sapiens (human)0.009
Cytochrome P450 11B1, mitochondrialHomo sapiens (human)2.62
Cytochrome P450 11B2, mitochondrialHomo sapiens (human)1.42
Amine oxidase [flavin-containing] A Rattus norvegicus (Norway rat)0.0009

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (75.00)18.2507
2000's1 (25.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Belluti, F; Bertucci, C; Bisi, A; Cavalli, A; Giorgio, E; Gobbi, S; Hartmann, RW; Paluszcak, A; Piazzi, L; Rampa, A; Recanatini, M; Rosini, C; Valenti, P1
Batzl, C; Bhatnagar, AS; Bowman, R; Furet, P; Häusler, A; Lang, M1
Batzl, C; Bhatnagar, AS; Lang, M; Schieweck, K1
Bhatnagar, S; Krishnamurthy, H; Krishnamurthy, HN; Moudgal, RN; Shetty, G1

Other Studies

4 other study(ies) available for cgp 47645 and letrozole

ArticleYear
Enantioselective nonsteroidal aromatase inhibitors identified through a multidisciplinary medicinal chemistry approach.
    Journal of medicinal chemistry, 2005, Nov-17, Volume: 48, Issue:23

    Topics: Aromatase; Aromatase Inhibitors; Benzopyrans; Circular Dichroism; Drug Design; Humans; Ligands; Microsomes; Models, Molecular; Molecular Conformation; Placenta; Quantitative Structure-Activity Relationship; Spectrophotometry, Ultraviolet; Stereoisomerism; Steroid 17-alpha-Hydroxylase

2005
Structure-activity relationships and binding model of novel aromatase inhibitors.
    The Journal of steroid biochemistry and molecular biology, 1993, Volume: 44, Issue:4-6

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Aromatase Inhibitors; Fadrozole; Female; Humans; Letrozole; Microsomes; Models, Molecular; Molecular Structure; Nitriles; Placenta; Pregnancy; Structure-Activity Relationship; Tetrazoles; Triazoles

1993
Anti-tumor and endocrine effects of non-steroidal aromatase inhibitors on estrogen-dependent rat mammary tumors.
    The Journal of steroid biochemistry and molecular biology, 1993, Volume: 44, Issue:4-6

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Aromatase Inhibitors; Estradiol; Female; Letrozole; Luteinizing Hormone; Mammary Neoplasms, Experimental; Molecular Structure; Nitriles; Organ Size; Rats; Rats, Sprague-Dawley; Tetrazoles; Triazoles; Uterus

1993
Effect of estrogen deprivation on the reproductive physiology of male and female primates.
    The Journal of steroid biochemistry and molecular biology, 1997, Volume: 61, Issue:3-6

    Topics: Animals; Aromatase; Aromatase Inhibitors; Enzyme Inhibitors; Estrogen Antagonists; Estrogens; Fadrozole; Female; Letrozole; Macaca radiata; Male; Nitriles; Pregnancy; Reproduction; Triazoles

1997