Page last updated: 2024-09-03

cgp 47645 and fadrozole

cgp 47645 has been researched along with fadrozole in 3 studies

Compound Research Comparison

Studies
(cgp 47645)
Trials
(cgp 47645)
Recent Studies (post-2010)
(cgp 47645)
Studies
(fadrozole)
Trials
(fadrozole)
Recent Studies (post-2010) (fadrozole)
81244332112

Protein Interaction Comparison

ProteinTaxonomycgp 47645 (IC50)fadrozole (IC50)
Cytochrome P450 3A4Homo sapiens (human)0.0063
AromataseHomo sapiens (human)0.0324
Cytochrome P450 11B1, mitochondrialHomo sapiens (human)0.0095
Cytochrome P450 11B2, mitochondrialMus musculus (house mouse)0.19
Cytochrome P450 11B2, mitochondrialHomo sapiens (human)0.0045
Cytochrome P450 11B2, mitochondrialRattus norvegicus (Norway rat)0.6

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Batzl, C; Bhatnagar, AS; Bowman, R; Furet, P; Häusler, A; Lang, M1
Durgam, VR; Tekmal, RR1
Bhatnagar, S; Krishnamurthy, H; Krishnamurthy, HN; Moudgal, RN; Shetty, G1

Other Studies

3 other study(ies) available for cgp 47645 and fadrozole

ArticleYear
Structure-activity relationships and binding model of novel aromatase inhibitors.
    The Journal of steroid biochemistry and molecular biology, 1993, Volume: 44, Issue:4-6

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Aromatase Inhibitors; Fadrozole; Female; Humans; Letrozole; Microsomes; Models, Molecular; Molecular Structure; Nitriles; Placenta; Pregnancy; Structure-Activity Relationship; Tetrazoles; Triazoles

1993
A novel in vitro and in vivo breast cancer model for testing inhibitors of estrogen biosynthesis and its action using mammary tumor cells with an activated int-5/aromatase gene.
    Cancer letters, 1997, Sep-16, Volume: 118, Issue:1

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Aminoglutethimide; Analysis of Variance; Anastrozole; Androstenedione; Animals; Antineoplastic Agents, Hormonal; Aromatase; Aromatase Inhibitors; Breast Neoplasms; Cell Division; Enzyme Inhibitors; Fadrozole; Female; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Humans; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Mice, Nude; Nitriles; Ovariectomy; Postmenopause; Triazoles; Tumor Cells, Cultured

1997
Effect of estrogen deprivation on the reproductive physiology of male and female primates.
    The Journal of steroid biochemistry and molecular biology, 1997, Volume: 61, Issue:3-6

    Topics: Animals; Aromatase; Aromatase Inhibitors; Enzyme Inhibitors; Estrogen Antagonists; Estrogens; Fadrozole; Female; Letrozole; Macaca radiata; Male; Nitriles; Pregnancy; Reproduction; Triazoles

1997