Compounds > cgp 42112a
Page last updated: 2024-09-03

cgp 42112a and losartan

cgp 42112a has been researched along with losartan in 123 studies

Compound Research Comparison

Studies
(cgp 42112a)		Trials
(cgp 42112a)		Recent Studies (post-2010)
(cgp 42112a)		Studies
(losartan)		Trials
(losartan)		Recent Studies (post-2010) (losartan)
2330357,2311,2452,118

Protein Interaction Comparison

ProteinTaxonomycgp 42112a (IC50)losartan (IC50)
Bile salt export pumpHomo sapiens (human)9.01
Cytochrome P450 2C9 Homo sapiens (human)2.882
Angiotensin-converting enzyme Homo sapiens (human)0.019
Atrial natriuretic peptide receptor 3Homo sapiens (human)0.0018
5-hydroxytryptamine receptor 1ARattus norvegicus (Norway rat)0.019
Type-1A angiotensin II receptor Rattus norvegicus (Norway rat)0.0247
Type-1B angiotensin II receptorRattus norvegicus (Norway rat)0.0234
Adenosine receptor A2aRattus norvegicus (Norway rat)0.0032
Type-1 angiotensin II receptorHomo sapiens (human)0.047
Type-1 angiotensin II receptorOryctolagus cuniculus (rabbit)0.025
Type-2 angiotensin II receptorRattus norvegicus (Norway rat)0.0118
Type-2 angiotensin II receptorHomo sapiens (human)0.019
Platelet glycoprotein VIHomo sapiens (human)4
Solute carrier organic anion transporter family member 1B3Homo sapiens (human)1.1481
Type-1 angiotensin II receptorCavia porcellus (domestic guinea pig)0.018
Solute carrier organic anion transporter family member 1B1Homo sapiens (human)0.2884

Research

Studies (123)

TimeframeStudies, this research(%)All Research%
pre-19901 (0.81)18.7374
1990's86 (69.92)18.2507
2000's26 (21.14)29.6817
2010's10 (8.13)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ambühl, P; Felix, D; Ferrario, CM; Imboden, H; Khosla, MC1
Campan, M; Costerousse, O; Desgranges, C; Gadeau, AP; Millet, D1
Beresford, MJ; Fitzsimons, JT1
Janiak, P; Pillon, A; Prost, JF; Vilaine, JP1
Bogdal, Y; Bottari, SP; Deschepper, CF; Obermüller, N; Zahs, KR1
Chiu, AT; Herblin, WF; Smith, RD; Timmermans, PB; Wong, PC1
Aiyar, N; Edwards, RM; Hill, DT; Keenan, RM; Stack, EJ; Weidley, EF; Weinstock, J1
Saavedra, JM; Strömberg, C; Tsutsumi, K; Viswanathan, M2
Balla, T; Baukal, AJ; Catt, KJ; Eng, S1
Bühlmayer, P; Criscione, L; de Gasparo, M; Herold, P; Kamber, B; Ostermayer, F; Thomann, H; Whitebread, S1
Chappell, MC; Diz, DI; Ferrario, CM; Jaiswal, N; Khosla, MC1
Bottari, SP; Culman, J; de Gasparo, M; Gohlke, P; Obermüller, N; Unger, T1
Saavedra, JM; Tsutsumi, K4
Raizada, MK; Sumners, C; Tang, W; Zelezna, B1
Diz, DI; Ferrario, CM; Jaiswal, N; Khosla, MC; Tallant, EA1
Diz, DI; Ferrario, CM; Khosla, MC; Tallant, EA1
Pfeilschifter, J1
de Gasparo, M; Kamber, B; Mele, M; Whitebread, S1
Bardhan, S; Inagami, T; Kambayashi, Y; Shirai, H; Takahasi, K1
Smith, RD1
el Ghissassi, M; Nicolaïdis, S; Thornton, SN1
Baldi, E; Catalioto, RM; Cioni, A; Finetti, G; Maggi, M; Mancina, R; Renzetti, AR; Serio, M1
de Gasparo, M; Levens, NR1
Brink, M; Bullock, G; de Gasparo, M; Rogg, H; Whitebread, S1
Smith, RD; Timmermans, PB1
Bottari, SP; Metzger, R; Paul, M; Steckelings, UM; Stoll, M; Unger, T1
Näveri, L; Saavedra, JM; Strömberg, C2
Campagnole-Santos, MJ; Fontes, MA; Guertzenstein, PG; Khosla, MC; Santos, RA; Silva, LC1
Lantelme, P; Liu, KL; Lo, M; Sassard, J1
Averill, DB; Barnes, KL; Fow, JE1
Chiueh, CC; de Oliveira, AM; Saavedra, JM; Viswanathan, M; Wu, RM1
Cumin, F; De Gasparo, M; Levens, N; Macari, D; Whitebread, S1
de Gasparo, M; De Hertogh, R; Kalenga, MK; Thomas, K1
Douglas, JG; Dulin, NO; Ernsberger, P; Suciu, DJ1
Janiak, P; Libert, O; Vilaine, JP1
Hong, KW; Rhim, BY; Shin, YW; Yoo, SE1
Freeman, EJ; Tallant, EA1
Barnes, KL; Ferrario, CM; McQueeney, AJ1
Bihoreau, C; Clauser, E; Conchon, S; Corvol, P; Monnot, C; Sirieix, ME1
Bertschin, S; Bühler, FR; Crabos, M; Eberhard, M; Erne, P; Evéquoz, D; Rogg, H1
Hogarty, DC; Phillips, MI; Tran, DN1
Barker, S; Jiménez, E; Montiel, M; Vinson, GP1
LeBrethon, MC; Ouali, R; Saez, JM1
Bensoussan, M; Mitchell, T; Reilly, T; Ronco, PM; Timmermans, PB; Verroust, PJ1
Bottari, S; De Gasparo, M; Levens, N; Macari, D; Whitebread, S1
Cooney, AS; Fitzsimons, JT1
Averill, DB; Ferrario, CM; Khosla, MC; Kumagai, H1
Bottari, SP; Brechler, V; de Gasparo, M; Jones, PW; Levens, NR1
Douglas, JG; Ernsberger, P; Hopfer, U; Ke, FC; Madhun, ZT; Zhou, J1
Speth, RC1
Benarous, R; Kermabon, AY; Lebrethon, MC; Naville, D; Rouer, E; Saez, JM1
Diz, DI; Ferrario, CM; Jaiswal, N; Jaiswal, RK; Tallant, EA1
Heidland, A; Ling, H; Schaefer, L; Schaefer, RM; Schnittler, HJ; Vamvakas, S1
Betteridge, LJ; Hughes, AD; Patel, MK; Schachter, M1
Bihoreau, C; Clauser, E; Conchon, S; Corvol, P; Curnow, KM; Monnot, C1
Cheung, WT; Sum, CS1
Coviello, A; Peral de Bruno, M1
Campagnole-Santos, MJ; Khosla, M; Oliveira, DR; Santos, GF; Santos, RA1
Collingwood, K; Demetroulis, C; Djahanbakhch, O; Mehta, JG; Puddefoot, JR; Saridogan, E; Vinson, GP1
Gelband, CH; Martens, JR; Posner, P; Sumners, C; Wang, D1
Braszko, J1
Bastien, NR; Ciuffo, GM; Lambert, C; Saavedra, JM1
Cheung, WT; Sum, CS; Wan, DC1
Heininger, F; Phillips, MI; Toffolo, S1
Kim, HJ; Kim, KS; Lee, EJ; Lee, JH; Lee, WJ; Park, JS; Yang, EK1
Miyazaki, H; Murakami, K; Ozawa, Y; Suzuki, Y1
Arendshorst, WJ; Chatziantoniou, C; Kurtz, A; Ruan, X; Wagner, C1
Campagnole-Santos, MJ; Fontes, MA; Khosla, MC; Lopes, OU; Martins Pinge, MC; Naves, V; Santos, RA1
Fluharty, SJ; He, P; Hines, J; Reagan, LP; Siemens, IR; Yang, XD; Yee, DK1
Brown, CL; Goode, AW; Ho, MM; Inwang, ER; Marsigliante, S; Payne, JG; Puddefoot, JR; Vinson, GP1
Dawda, R; Demetroulis, C; Djahanbakhch, O; Hall, AJ; Puddefoot, JR; Saridogan, E; Vinson, GP1
Andreis, PG; Belloni, AS; Gottardo, G; Macchi, V; Malendowicz, LK; Nussdorfer, GG1
Häuser, W; Jöhren, O; Saavedra, JM1
Carey, RM; Guerrant, RL; Jin, XH; Siragy, HM; Wang, ZQ1
Kucerová, D; Sloncová, E; Sovová, V; Zelezná, B1
Davis, EA; Widdop, RE; Zwart, AS1
Baum, M; Quan, A1
Cheung, WT; Ho, WK; Ip, TM; Luk, SK; Wan, DC; Yeung, SY; Yiu, AK1
Côté, F; Do, TH; Gallo, JM; Gallo-Payet, N; Laflamme, L1
de Arruda Camargo, LA; Saad, WA1
Jung, YS; Lee, BH; Lee, SH; Seo, HW; Shin, HS; Yoo, SE1
Arendshorst, WJ; Coffman, TM; Oliverio, MI; Ruan, X1
Sakata, Y; Wada, M; Watanabe, T1
Adamy, C; Adnot, S; Chassagne, C; Dubois-Randé, JL; Eddahibi, S; Marotte, F; Rideau, D; Samuel, JL; Teiger, E1
Mifune, M; Miyazaki, H; Saruta, T; Sasamura, H; Shimizu-Hirota, R1
de Zeeuw, D; Filipeanu, CM; Henning, RH; Nelemans, A1
Fluharty, SJ; Heerding, JN; Hines, J; Yee, DK1
Fischer, JW; Hahn, AW; Stoll, M; Unger, T1
Bautista, R; Escalante, B; Hernández, J; Oyekan, A; Sánchez, A1
Fabiani, ME; Frauman, AG; Johnston, CI; Sourial, M; Thomas, WG1
Carey, RM; Howell, NL; Jin, XH; Siragy, HM1
Breigeiron, MK; Lucion, AB; Morris, M; Sanvitto, GL1
Elia, MG; Greco, S; Marsigliante, S; Muscella, A; Storelli, C1
Chiba, S; Inada, Y; Nakane, T1
Jarrott, B; Lawrence, AJ; Roulston, CL; Widdop, RE1
Bagi, EE; Fekete, E; Lénárd, L1
Benndorf, R; Böger, RH; Ergün, S; Steenpass, A; Wieland, T1
Cerri, PS; de Arruda Camargo, LA; Saad, WA1
Cerri, PS; de Arruda Camargo, GM; de Arruda Camargo, LA; Saad, WA1
Andrade, RR; Camargo, LA; Mima, EG; Saad, WA1
Abrão Saad, W; Antonio De Arruda Camargo, L; Garcia, G; Guarda, I; Izabel Gutierrez, L; Saad Guarda, R; Sérgio Cerri, P; Simões, S1
Martins, AR; Pelegrini-da-Silva, A; Prado, WA1
Antunes-Rodrigues, J; Camargo, LA; Guarda, IF; Guarda, RS; Saad, WA1
Hsieh, PS1
Antônio de Arruda Camargo, L; Maria Pavan de Arruda Camargo, G; Saad, WA1
Akira, T; Egi, Y; Maruyama, T; Matsumura, Y; Ohkita, M; Sasaoka, T; Takaoka, M; Tawa, M; Yamamoto, A1
Falone, AE; Khalil, RA; Koledova, VV; Qiao, X; Stennett, AK1
Guethe, LM; Juliano, MA; Martins, AR; Pelegrini-da-Silva, A; Prado, WA; Rosa, E1
Kamata, K; Kobayashi, T; Matsumoto, T; Taguchi, K1
Axelband, F; Costa-Neto, CM; Dias, J; Ferrão, FM; Lara, LS; Miranda, F; Reis, RI; Vieyra, A1
Garvin, JL; Hong, NJ1
Abdulla, MH; Johns, EJ2
Cha, SA; Gao, S; Kim, SH; Park, BH; Park, BM; Park, WH1
Chang, Y; Hu, S; Huang, Q; Sun, W; Wang, D; Wang, Q; Wei, W; Wu, J; Wu, Y; Yuan, J; Zhao, W; Zhou, A; Zhu, J1
Bae, DS; Cho, YJ; Choi, CH; Choi, JJ; Do, IG; Jeon, HK; Kim, BG; Kim, TJ; Lee, JK; Lee, JW; Lee, YY; Park, YA; Ryu, JY; Song, SY1
Castillo, EF; Castillo, MC; Guevara, G; López, JS; López, P; López, RM1
Cui, H; Liang, H; Lv, J; Wang, H; Wang, M; Wang, S; Ye, F; Zheng, Y; Zhu, Y1

Reviews

3 review(s) available for cgp 42112a and losartan

ArticleYear
Angiotensin II receptor subtypes.
    American journal of hypertension, 1992, Volume: 5, Issue:6 Pt 1

    Topics: Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Binding Sites; Biphenyl Compounds; Drug Resistance; Humans; Imidazoles; Losartan; Oligopeptides; Pyridines; Receptors, Angiotensin; Terminology as Topic; Tetrazoles; Tissue Distribution

1992
Pharmacology of angiotensin II receptors in the kidney.
    Kidney international, 1994, Volume: 46, Issue:6

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Humans; Imidazoles; Kidney; Losartan; Oligopeptides; Pyridines; Rats; Receptors, Angiotensin; Species Specificity; Tetrazoles; Tissue Distribution

1994
Human angiotensin receptor subtypes.
    Current opinion in nephrology and hypertension, 1994, Volume: 3, Issue:1

    Topics: Angiotensin I; Angiotensin II; Angiotensin III; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; DNA, Complementary; Gene Library; Humans; Imidazoles; Losartan; Oligopeptides; Pyridines; Receptors, Angiotensin; Tetrazoles

1994

Other Studies

120 other study(ies) available for cgp 42112a and losartan

ArticleYear
Effects of angiotensin II and its selective antagonists on inferior olivary neurones.
    Regulatory peptides, 1992, Sep-03, Volume: 41, Issue:1

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Autoradiography; Biphenyl Compounds; Imidazoles; Losartan; Neurons; Oligopeptides; Olivary Nucleus; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin; Synaptic Transmission; Tetrazoles

1992
Effects of angiotensins on cellular hypertrophy and c-fos expression in cultured arterial smooth muscle cells.
    European journal of biochemistry, 1992, Jun-01, Volume: 206, Issue:2

    Topics: Angiotensin-Converting Enzyme Inhibitors; Angiotensins; Animals; Biphenyl Compounds; Captopril; Cells, Cultured; DNA; Imidazoles; Indoles; Losartan; Muscle, Smooth, Vascular; Oligopeptides; Proto-Oncogene Proteins c-fos; Rats; Rats, Inbred WKY; RNA; Tetrazoles

1992
Intracerebroventricular angiotensin II-induced thirst and sodium appetite in rat are blocked by the AT1 receptor antagonist, Losartan (DuP 753), but not by the AT2 antagonist, CGP 42112B.
    Experimental physiology, 1992, Volume: 77, Issue:5

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Appetite; Biphenyl Compounds; Imidazoles; Injections, Intraventricular; Losartan; Male; Oligopeptides; Rats; Rats, Wistar; Sodium, Dietary; Tetrazoles; Thirst

1992
Role of angiotensin subtype 2 receptor in neointima formation after vascular injury.
    Hypertension (Dallas, Tex. : 1979), 1992, Volume: 20, Issue:6

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Biphenyl Compounds; Carotid Arteries; Carotid Artery Injuries; Catheterization; Hyperplasia; Imidazoles; Indoles; Losartan; Male; Oligopeptides; Perindopril; Rats; Rats, Wistar; Receptors, Angiotensin; Tetrazoles; Tunica Intima

1992
Characterization and distribution of angiotensin II binding sites in fetal and neonatal astrocytes from different rat brain regions.
    Brain research, 1992, Jul-10, Volume: 585, Issue:1-2

    Topics: Angiotensin II; Animals; Animals, Newborn; Astrocytes; Binding Sites; Binding, Competitive; Biphenyl Compounds; Brain; Cells, Cultured; Fetus; Imidazoles; Losartan; Oligopeptides; Rats; Saralasin; Tetrazoles; Tissue Distribution

1992
Characterization of renal angiotensin II receptors using subtype selective antagonists.
    The Journal of pharmacology and experimental therapeutics, 1992, Volume: 260, Issue:3

    Topics: Acrylates; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Binding, Competitive; Biphenyl Compounds; Dithiothreitol; Guanylyl Imidodiphosphate; Imidazoles; In Vitro Techniques; Kidney; Losartan; Oligopeptides; Pyridines; Rats; Rats, Inbred Strains; Receptors, Angiotensin; Tetrazoles; Thiophenes

1992
Angiotensin-II receptor subtypes in fetal tissue of the rat: autoradiography, guanine nucleotide sensitivity, and association with phosphoinositide hydrolysis.
    Endocrinology, 1991, Volume: 129, Issue:2

    Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Autoradiography; Binding, Competitive; Fetus; Gestational Age; Guanine Nucleotides; Guanosine 5'-O-(3-Thiotriphosphate); Hydrolysis; Imidazoles; Losartan; Oligopeptides; Phosphatidylinositols; Pyridines; Rats; Rats, Inbred Strains; Receptors, Angiotensin; Tetrazoles; Tissue Distribution

1991
Angiotensin II receptor subtypes and biological responses in the adrenal cortex and medulla.
    Molecular pharmacology, 1991, Volume: 40, Issue:3

    Topics: Adrenal Cortex; Adrenal Medulla; Aldosterone; Angiotensin II; Animals; Binding Sites; Biphenyl Compounds; Cattle; Cyclic AMP; Imidazoles; In Vitro Techniques; Losartan; Oligopeptides; Rats; Rats, Inbred Strains; Receptors, Angiotensin; Tetrazoles; Zona Glomerulosa

1991
Binding characteristics and vascular effects of various angiotensin II antagonists.
    Journal of cardiovascular pharmacology, 1990, Volume: 16 Suppl 4

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensins; Animals; Aorta; Biphenyl Compounds; Dose-Response Relationship, Drug; Female; Humans; Imidazoles; In Vitro Techniques; Ligands; Losartan; Muscle, Smooth, Vascular; Oligopeptides; Rabbits; Rats; Receptors, Angiotensin; Saralasin; Uterus

1990
Type-1 and type-2 angiotensin II receptors in fetal rat brain.
    European journal of pharmacology, 1991, May-30, Volume: 198, Issue:1

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Autoradiography; Biphenyl Compounds; Brain; Female; Fetus; Imidazoles; Iodine Radioisotopes; Losartan; Oligopeptides; Pregnancy; Rats; Rats, Inbred Strains; Receptors, Angiotensin; Staining and Labeling; Tetrazoles

1991
Stimulation of endothelial cell prostaglandin production by angiotensin peptides. Characterization of receptors.
    Hypertension (Dallas, Tex. : 1979), 1992, Volume: 19, Issue:2 Suppl

    Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Cells, Cultured; Dinoprostone; Endothelium, Vascular; Epoprostenol; Imidazoles; Losartan; Oligopeptides; Prostaglandins; Pyridines; Receptors, Angiotensin; Tetrazoles

1992
Distribution of angiotensin II receptor subtypes in rat brain nuclei.
    Neuroscience letters, 1991, Oct-28, Volume: 132, Issue:1

    Topics: Angiotensin II; Animals; Binding, Competitive; Biphenyl Compounds; Brain; Brain Stem; Hypothalamus; Imidazoles; Iodine Radioisotopes; Losartan; Male; Mesencephalon; Oligopeptides; Organ Specificity; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, Angiotensin; Saralasin; Tetrazoles

1991
Characterization and development of angiotensin II receptor subtypes (AT1 and AT2) in rat brain.
    The American journal of physiology, 1991, Volume: 261, Issue:1 Pt 2

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Autoradiography; Binding, Competitive; Brain; Imidazoles; Losartan; Male; Oligopeptides; Rats; Rats, Inbred Strains; Receptors, Angiotensin; Tetrazoles; Tissue Distribution

1991
Angiotensin II receptor subtypes are coupled with distinct signal-transduction mechanisms in neurons and astrocytes from rat brain.
    Proceedings of the National Academy of Sciences of the United States of America, 1991, Sep-01, Volume: 88, Issue:17

    Topics: Angiotensin II; Animals; Animals, Newborn; Astrocytes; Binding, Competitive; Biphenyl Compounds; Brain; Cells, Cultured; Imidazoles; Kinetics; Ligands; Losartan; Neurons; Oligopeptides; Pyridines; Rats; Rats, Inbred Strains; Receptors, Angiotensin; Signal Transduction; Tetrazoles

1991
Angiotensin-II receptor subtypes in median eminence and basal forebrain areas involved in regulation of pituitary function.
    Endocrinology, 1991, Volume: 129, Issue:6

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Autoradiography; Binding, Competitive; Biphenyl Compounds; Cerebral Arteries; Dithiothreitol; Imidazoles; Losartan; Male; Median Eminence; Oligopeptides; Pituitary Gland; Prosencephalon; Pyridines; Rats; Rats, Inbred Strains; Receptors, Angiotensin; Tetrazoles

1991
Differential development of angiotensin II receptor subtypes in the rat brain.
    Endocrinology, 1991, Volume: 128, Issue:1

    Topics: Aging; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Brain; Imidazoles; Kinetics; Losartan; Male; Oligopeptides; Organ Specificity; Rats; Rats, Inbred Strains; Receptors, Angiotensin; Tetrazoles

1991
Quantitative autoradiography reveals different angiotensin II receptor subtypes in selected rat brain nuclei.
    Journal of neurochemistry, 1991, Volume: 56, Issue:1

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Autoradiography; Binding, Competitive; Brain; Brain Chemistry; Dithiothreitol; Imidazoles; Losartan; Male; Medulla Oblongata; Oligopeptides; Paraventricular Hypothalamic Nucleus; Rats; Rats, Inbred Strains; Receptors, Angiotensin; Subfornical Organ; Tetrazoles; Tissue Distribution

1991
Characterization of angiotensin receptors mediating prostaglandin synthesis in C6 glioma cells.
    The American journal of physiology, 1991, Volume: 260, Issue:5 Pt 2

    Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Glioma; Imidazoles; Losartan; Oligopeptides; Peptide Fragments; Prostaglandins; Receptors, Angiotensin; Tetrazoles; Tumor Cells, Cultured

1991
Identification and regulation of angiotensin II receptor subtypes on NG108-15 cells.
    Hypertension (Dallas, Tex. : 1979), 1991, Volume: 17, Issue:6 Pt 2

    Topics: 1-Sarcosine-8-Isoleucine Angiotensin II; Angiotensin II; Angiotensin Receptor Antagonists; Binding, Competitive; Calcium; Hybrid Cells; Imidazoles; Losartan; Neurons; Oligopeptides; Receptors, Angiotensin; Signal Transduction; Tetrazoles; Tumor Cells, Cultured

1991
Angiotensin II B-type receptor mediates phosphoinositide hydrolysis in mesangial cells.
    European journal of pharmacology, 1990, Aug-02, Volume: 184, Issue:1

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Cells, Cultured; Glomerular Mesangium; Hydrolysis; Imidazoles; Inositol 1,4,5-Trisphosphate; Losartan; Oligopeptides; Phosphatidylinositols; Rats; Receptors, Angiotensin; Stimulation, Chemical

1990
Preliminary biochemical characterization of two angiotensin II receptor subtypes.
    Biochemical and biophysical research communications, 1989, Aug-30, Volume: 163, Issue:1

    Topics: Adrenal Glands; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Binding, Competitive; Biphenyl Compounds; Dithiothreitol; Female; Humans; Imidazoles; Losartan; Muscle, Smooth; Oligopeptides; Rats; Receptors, Angiotensin; Uterus

1989
Protein tyrosine phosphatase inhibition by angiotensin II in rat pheochromocytoma cells through type 2 receptor, AT2.
    Biochemical and biophysical research communications, 1994, Jan-14, Volume: 198, Issue:1

    Topics: Adrenal Gland Neoplasms; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Cell Membrane; Chromatography, Affinity; Guanosine Diphosphate; Imidazoles; Losartan; Oligopeptides; PC12 Cells; Pertussis Toxin; Pheochromocytoma; Phosphates; Phosphoproteins; Phosphorus Radioisotopes; Phosphotyrosine; Protein Tyrosine Phosphatases; Pyridines; Rats; Receptors, Angiotensin; Tetrazoles; Thionucleotides; Tyrosine; Virulence Factors, Bordetella

1994
Identification of atypical (non-AT1, non-AT2) angiotensin binding sites with high affinity for angiotensin I on IEC-18 rat intestinal epithelial cells.
    FEBS letters, 1995, Oct-16, Volume: 373, Issue:3

    Topics: 1-Sarcosine-8-Isoleucine Angiotensin II; Angiotensin I; Angiotensin II; Angiotensin III; Angiotensin Receptor Antagonists; Animals; Binding Sites; Binding, Competitive; Biphenyl Compounds; Cell Line; Epithelium; Imidazoles; Intestinal Mucosa; Intestine, Small; Losartan; Oligopeptides; Peptide Fragments; Pyridines; Rats; Receptors, Angiotensin; Tetrazoles

1995
Angiotensin II-induced thirst, but not sodium appetite, via AT1 receptors in organum cavum prelamina terminalis.
    The American journal of physiology, 1995, Volume: 268, Issue:6 Pt 2

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Appetite; Biphenyl Compounds; Dose-Response Relationship, Drug; Imidazoles; Losartan; Male; Microinjections; Oligopeptides; Prosencephalon; Rats; Rats, Wistar; Receptors, Angiotensin; Sodium, Dietary; Tetrazoles; Thirst

1995
Identification and characterization of functional angiotensin II receptors in human neuroblastoma cells.
    Regulatory peptides, 1995, Apr-14, Volume: 56, Issue:2-3

    Topics: 1-Sarcosine-8-Isoleucine Angiotensin II; Angiotensin II; Angiotensin III; Angiotensin Receptor Antagonists; Binding, Competitive; Biphenyl Compounds; Calcium; Cyclic AMP; Dose-Response Relationship, Drug; Humans; Imidazoles; Kinetics; Losartan; Neuroblastoma; Oligopeptides; Pyridines; Receptors, Angiotensin; Tetrazoles; Tumor Cells, Cultured; Vasoactive Intestinal Peptide

1995
Localization of angiotensin II receptor subtypes in the rabbit heart.
    Journal of molecular and cellular cardiology, 1995, Volume: 27, Issue:1

    Topics: Acetylcholinesterase; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Autoradiography; Biphenyl Compounds; Cell Membrane; Heart Atria; Heart Conduction System; Imidazoles; Immunohistochemistry; Iodine Radioisotopes; Losartan; Male; Myocardium; Oligopeptides; Rabbits; Receptors, Angiotensin; Tetrazoles

1995
The angiotensin AT2-receptor mediates inhibition of cell proliferation in coronary endothelial cells.
    The Journal of clinical investigation, 1995, Volume: 95, Issue:2

    Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Aorta; Base Sequence; Binding, Competitive; Biphenyl Compounds; Cell Division; Cells, Cultured; Coronary Vessels; DNA; DNA Primers; Dose-Response Relationship, Drug; Endothelium, Vascular; Gene Expression; Imidazoles; Kinetics; Losartan; Molecular Sequence Data; Muscle, Smooth, Vascular; Oligopeptides; Polymerase Chain Reaction; Pyridines; Rats; Receptors, Angiotensin; RNA, Messenger; Tetrazoles; Thymidine

1995
Angiotensin II AT1 receptor mediated contraction of the perfused rat cerebral artery.
    Neuroreport, 1994, Nov-21, Volume: 5, Issue:17

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Cerebral Arteries; Imidazoles; In Vitro Techniques; Losartan; Male; Oligopeptides; Perfusion; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin; Tetrazoles; Vasoconstriction

1994
Evidence that angiotensin-(1-7) plays a role in the central control of blood pressure at the ventro-lateral medulla acting through specific receptors.
    Brain research, 1994, Nov-28, Volume: 665, Issue:1

    Topics: Analysis of Variance; Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Blood Pressure; Imidazoles; Losartan; Male; Medulla Oblongata; Oligopeptides; Peptide Fragments; Rats; Rats, Wistar; Tetrazoles

1994
Subtype 2 of angiotensin II receptors controls pressure-natriuresis in rats.
    The Journal of clinical investigation, 1995, Volume: 95, Issue:3

    Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Blood Pressure; Diuresis; Glomerular Filtration Rate; Imidazoles; Losartan; Male; Natriuresis; Oligopeptides; Perfusion; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin; Renal Circulation; Tetrazoles

1995
Mechanisms of angiotensin-induced hypotension and bradycardia in the medial solitary tract nucleus.
    The American journal of physiology, 1994, Volume: 267, Issue:1 Pt 2

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Bradycardia; Cardiovascular System; Glutamates; Glutamic Acid; Hypotension; Imidazoles; Losartan; Male; Medulla Oblongata; Microinjections; Oligopeptides; Rats; Rats, Sprague-Dawley; Tetrazoles; Vagus Nerve

1994
[125I]CGP 42112 reveals a non-angiotensin II binding site in 1-methyl-4-phenylpyridine (MPP+)-induced brain injury.
    Cellular and molecular neurobiology, 1994, Volume: 14, Issue:1

    Topics: 1-Methyl-4-phenylpyridinium; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Autoradiography; Binding Sites; Biphenyl Compounds; Brain; Brain Injuries; Imidazoles; Iodine Radioisotopes; Losartan; Male; Oligopeptides; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin; Substantia Nigra; Tetrazoles

1994
Renal actions of the angiotensin AT2 receptor ligands CGP 42112 and PD 123319 after blockade of the renin-angiotensin system.
    European journal of pharmacology, 1994, Jun-23, Volume: 259, Issue:1

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Blood Pressure; Enalaprilat; Imidazoles; Kidney; Losartan; Male; Oligopeptides; Pyridines; Rats; Rats, Sprague-Dawley; Renin-Angiotensin System; Tetrazoles; Vascular Resistance

1994
Angiotensin II induces human placental lactogen and pregnancy-specific beta 1-glycoprotein secretion via an angiotensin AT1 receptor.
    European journal of pharmacology, 1994, Jul-15, Volume: 268, Issue:2

    Topics: Angiotensin II; Biphenyl Compounds; Female; Humans; Imidazoles; Losartan; Oligopeptides; Placenta; Placental Lactogen; Pregnancy; Pregnancy-Specific beta 1-Glycoproteins; Receptors, Angiotensin; Tetrazoles; Trophoblasts

1994
Rabbit renal epithelial angiotensin II receptors.
    The American journal of physiology, 1994, Volume: 267, Issue:5 Pt 2

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Binding, Competitive; Biphenyl Compounds; Dithiothreitol; Dose-Response Relationship, Drug; Epithelium; Guanosine 5'-O-(3-Thiotriphosphate); Imidazoles; Iodine Radioisotopes; Kidney Cortex; Kinetics; Losartan; Male; Microvilli; Oligopeptides; Pyridines; Rabbits; Radioligand Assay; Receptors, Angiotensin; Tetrazoles

1994
Role of the renin-angiotensin system in neointima formation after injury in rabbits.
    Hypertension (Dallas, Tex. : 1979), 1994, Volume: 24, Issue:6

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Biphenyl Compounds; Blood Pressure; Bradykinin; Heart Rate; Imidazoles; Indoles; Losartan; Male; Oligopeptides; Perindopril; Rabbits; Receptors, Angiotensin; Renin-Angiotensin System; Tetrazoles; Tunica Intima; Wound Healing

1994
Characterization of PD 121981- and CGP 42112-induced unmasking of low concentration effects of angiotensin II in rabbit abdominal aorta.
    The Journal of pharmacology and experimental therapeutics, 1994, Volume: 271, Issue:3

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Aorta, Abdominal; Biphenyl Compounds; Calcium; Dithiothreitol; Female; Gallic Acid; Imidazoles; Losartan; Male; Nifedipine; Oligopeptides; Pyridines; Rabbits; Tetrazoles; Vasoconstriction

1994
Vascular smooth-muscle cells contain AT1 angiotensin receptors coupled to phospholipase D activation.
    The Biochemical journal, 1994, Dec-01, Volume: 304 ( Pt 2)

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Aorta, Thoracic; Biphenyl Compounds; Calcium; Diglycerides; Enzyme Activation; Imidazoles; Kinetics; Losartan; Muscle, Smooth, Vascular; Oligopeptides; Peptide Fragments; Phospholipase D; Rats; Receptors, Angiotensin; Signal Transduction; Tetrazoles

1994
Receptor subtype that mediates the neuronal effects of angiotensin II in the rat dorsal medulla.
    Brain research bulletin, 1993, Volume: 31, Issue:1-2

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Electrophysiology; Glutamates; Glutamic Acid; Imidazoles; In Vitro Techniques; Losartan; Medulla Oblongata; Neurons; Oligopeptides; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin; Tetrazoles

1993
Synthetic cDNA encoding the rat AT1a receptor: a useful tool for structure-function relationship analysis.
    Biochemical and biophysical research communications, 1994, Mar-30, Volume: 199, Issue:3

    Topics: Angiotensin II; Angiotensin III; Angiotensin Receptor Antagonists; Animals; Base Sequence; Biphenyl Compounds; CHO Cells; Codon; Cricetinae; DNA, Complementary; Imidazoles; Kinetics; Losartan; Molecular Sequence Data; Mutagenesis, Site-Directed; Oligodeoxyribonucleotides; Oligopeptides; Open Reading Frames; Pyridines; Rats; Receptors, Angiotensin; Restriction Mapping; Saralasin; Signal Transduction; Structure-Activity Relationship; Tetrazoles; Transfection

1994
Identification of AT1 receptors on human platelets and decreased angiotensin II binding in hypertension.
    Journal of hypertension. Supplement : official journal of the International Society of Hypertension, 1993, Volume: 11, Issue:5

    Topics: Adult; Angiotensin II; Angiotensin Receptor Antagonists; Binding, Competitive; Biphenyl Compounds; Blood Platelets; Humans; Hypertension; Imidazoles; In Vitro Techniques; Kinetics; Losartan; Middle Aged; Oligopeptides; Receptors, Angiotensin; Tetrazoles

1993
Involvement of angiotensin receptor subtypes in osmotically induced release of vasopressin.
    Brain research, 1994, Feb-21, Volume: 637, Issue:1-2

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Arginine Vasopressin; Biphenyl Compounds; Imidazoles; Injections, Intraventricular; Losartan; Male; Oligopeptides; Osmolar Concentration; Pyridines; Radioimmunoassay; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin; Saline Solution, Hypertonic; Tetrazoles

1994
Angiotensin II receptor isoforms in the rat adrenal gland: studies with the selective subtype antagonists DuP 753 and CGP42112A.
    Journal of molecular endocrinology, 1993, Volume: 11, Issue:1

    Topics: Adrenal Glands; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Autoradiography; Binding, Competitive; Biphenyl Compounds; Imidazoles; Iodine Radioisotopes; Isoelectric Focusing; Kinetics; Losartan; Male; Oligopeptides; Rats; Rats, Wistar; Receptors, Angiotensin; Tetrazoles

1993
Identification and characterization of angiotensin-II receptor subtypes in cultured bovine and human adrenal fasciculata cells and PC12W cells.
    Endocrinology, 1993, Volume: 133, Issue:6

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Autoradiography; Biphenyl Compounds; Cattle; Cells, Cultured; Chemical Phenomena; Chemistry, Physical; Cross-Linking Reagents; Dithiothreitol; Electrophoresis, Polyacrylamide Gel; Humans; Imidazoles; Losartan; Macromolecular Substances; Oligopeptides; PC12 Cells; Receptors, Angiotensin; Tetrazoles; Zona Fasciculata

1993
Angiotensin II AT2 receptor stimulation extends the upper limit of cerebral blood flow autoregulation: agonist effects of CGP 42112 and PD 123319.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 1994, Volume: 14, Issue:1

    Topics: 1-Sarcosine-8-Isoleucine Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Blood Pressure; Cerebrovascular Circulation; Homeostasis; Imidazoles; Injections, Intravenous; Losartan; Male; Oligopeptides; Phenylephrine; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin; Tetrazoles

1994
Immunological reactivity of angiotensin II receptor antagonists: possible implications for receptor binding sites.
    European journal of pharmacology, 1993, Oct-15, Volume: 247, Issue:2

    Topics: 1-Sarcosine-8-Isoleucine Angiotensin II; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antibodies, Monoclonal; Antihypertensive Agents; Biphenyl Compounds; Imidazoles; In Vitro Techniques; Indicators and Reagents; Iodine Radioisotopes; Losartan; Molecular Conformation; Oligopeptides; Pyridines; Rats; Receptors, Angiotensin; Saralasin; Tetrazoles

1993
Renal actions of the selective angiotensin AT2 receptor ligands CGP 42112B and PD 123319 in the sodium-depleted rat.
    European journal of pharmacology, 1993, Nov-02, Volume: 249, Issue:1

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Blood Pressure; Diet, Sodium-Restricted; Glomerular Filtration Rate; Imidazoles; Kidney; Losartan; Male; Oligopeptides; Potassium; Pyridines; Radioligand Assay; Rats; Rats, Sprague-Dawley; Renal Circulation; Sodium; Tetrazoles; Vascular Resistance

1993
The effect of the putative AT2 agonist, p-aminophenylalanine6 angiotensin II, on thirst and sodium appetite in rats.
    Experimental physiology, 1993, Volume: 78, Issue:6

    Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Appetite; Biphenyl Compounds; Drinking; Imidazoles; Injections, Intraventricular; Losartan; Male; Oligopeptides; Peptide Fragments; Pyridines; Rats; Rats, Wistar; Receptors, Angiotensin; Sodium Chloride, Dietary; Tetrazoles; Thirst

1993
Role of nitric oxide and angiotensin II in the regulation of sympathetic nerve activity in spontaneously hypertensive rats.
    Hypertension (Dallas, Tex. : 1979), 1993, Volume: 21, Issue:4

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Arginine; Biphenyl Compounds; Blood Pressure; Dipeptides; Heart Rate; Imidazoles; Lisinopril; Losartan; Male; Nitric Oxide; Oligopeptides; omega-N-Methylarginine; Pressoreceptors; Rats; Rats, Inbred SHR; Reflex; Tetrazoles

1993
Agonistic and antagonistic properties of angiotensin analogs at the AT2 receptor in PC12W cells.
    Regulatory peptides, 1993, Mar-19, Volume: 44, Issue:2

    Topics: 1-Sarcosine-8-Isoleucine Angiotensin II; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Binding, Competitive; Biphenyl Compounds; Cyclic GMP; Imidazoles; Losartan; Oligopeptides; PC12 Cells; Pyridines; Rats; Receptors, Angiotensin; Tetrazoles

1993
Signal transduction mediated by angiotensin II receptor subtypes expressed in rat renal mesangial cells.
    Regulatory peptides, 1993, Mar-19, Volume: 44, Issue:2

    Topics: Adenylyl Cyclase Inhibitors; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Calcium; Cell Division; Cells, Cultured; Glomerular Mesangium; Imidazoles; Losartan; Oligopeptides; Protein Biosynthesis; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin; Signal Transduction; Tetrazoles

1993
[125I]CGP 42112 binding reveals differences between rat brain and adrenal AT2 receptor binding sites.
    Regulatory peptides, 1993, Mar-19, Volume: 44, Issue:2

    Topics: 1-Sarcosine-8-Isoleucine Angiotensin II; Adrenal Glands; Analysis of Variance; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Binding, Competitive; Biphenyl Compounds; Brain; Chromatography, High Pressure Liquid; Imidazoles; Losartan; Male; Mercaptoethanol; Oligopeptides; Oxidation-Reduction; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin; Tetrazoles

1993
Characterization and regulation of the angiotensin II type-1 receptor (binding and mRNA) in human adrenal fasciculata-reticularis cells.
    FEBS letters, 1993, Apr-26, Volume: 321, Issue:2-3

    Topics: Adult; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Binding, Competitive; Biphenyl Compounds; Cell Line; Cells, Cultured; Cloning, Molecular; Gene Expression Regulation; Homeostasis; Humans; Imidazoles; Kinetics; Losartan; Oligodeoxyribonucleotides; Oligopeptides; Receptors, Angiotensin; RNA, Messenger; Tetrazoles; Transfection; Zona Fasciculata; Zona Reticularis

1993
Differential regulation of prostaglandin synthesis by angiotensin peptides in porcine aortic smooth muscle cells: subtypes of angiotensin receptors involved.
    The Journal of pharmacology and experimental therapeutics, 1993, Volume: 265, Issue:2

    Topics: Angiotensin Receptor Antagonists; Angiotensins; Animals; Aorta; Biphenyl Compounds; Calcium; Cells, Cultured; Imidazoles; Losartan; Muscle, Smooth, Vascular; Oligopeptides; Peptide Fragments; Prostaglandins; Receptors, Angiotensin; Swine; Tetrazoles

1993
Angiotensin-II-induced cell hypertrophy: potential role of impaired proteolytic activity in cultured LLC-PK1 cells.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 1995, Volume: 10, Issue:8

    Topics: Analysis of Variance; Angiotensin II; Animals; Biphenyl Compounds; Calcium; Calcium Channel Blockers; Cell Count; Cells, Cultured; Cycloheximide; DNA; Hypertrophy; Imidazoles; Kidney; LLC-PK1 Cells; Losartan; Oligopeptides; Protein Synthesis Inhibitors; Proteins; Swine; Tetrazoles; Verapamil

1995
Angiotensin II receptors are exclusively of the AT1 subtype in cultured human vascular smooth muscle cells.
    Biochemical Society transactions, 1995, Volume: 23, Issue:3

    Topics: 1-Sarcosine-8-Isoleucine Angiotensin II; Angiotensin II; Angiotensin Receptor Antagonists; Binding, Competitive; Biphenyl Compounds; Cells, Cultured; Humans; Imidazoles; Kinetics; Losartan; Muscle, Smooth, Vascular; Oligopeptides; Receptors, Angiotensin; Saralasin; Tetrazoles

1995
Polar residues in the transmembrane domains of the type 1 angiotensin II receptor are required for binding and coupling. Reconstitution of the binding site by co-expression of two deficient mutants.
    The Journal of biological chemistry, 1996, Jan-19, Volume: 271, Issue:3

    Topics: Amino Acid Sequence; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Asparagine; Base Sequence; Binding Sites; Biphenyl Compounds; Cell Line; Chlorocebus aethiops; CHO Cells; Cricetinae; DNA Primers; Imidazoles; Inositol Phosphates; Kinetics; Losartan; Molecular Sequence Data; Mutagenesis; Mutagenesis, Site-Directed; Oligodeoxyribonucleotides; Oligopeptides; Point Mutation; Polymerase Chain Reaction; Rats; Receptors, Angiotensin; Recombinant Proteins; Sequence Deletion; Serine; Tetrazoles; Transfection

1996
Characterization of contractile response to angiotensin in epididymal rat vas deferens.
    Pharmacology, 1995, Volume: 51, Issue:2

    Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Biphenyl Compounds; Dose-Response Relationship, Drug; Electric Stimulation; Epididymis; Imidazoles; In Vitro Techniques; Losartan; Male; Muscle Contraction; Muscle, Smooth; Oligopeptides; Rats; Rats, Sprague-Dawley; Sympathetic Nervous System; Tetrazoles; Vas Deferens; Vasoconstrictor Agents

1995
Effects of angiotensin II antagonists on the contractile and hydrosmotic effect of AT II and AT III in the toad (Bufo arenarum).
    Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology, 1996, Volume: 165, Issue:7

    Topics: Analysis of Variance; Angiotensin II; Angiotensin III; Animals; Antihypertensive Agents; Aorta; Biphenyl Compounds; Bufo arenarum; Dose-Response Relationship, Drug; Drug Interactions; Female; Imidazoles; Losartan; Male; Muscle Contraction; Muscle, Smooth, Vascular; Oligopeptides; Osmolar Concentration; Osmosis; Pyridines; Skin; Tetrazoles; Vasoconstrictor Agents

1996
Changes in the baroreflex control of heart rate produced by central infusion of selective angiotensin antagonists in hypertensive rats.
    Hypertension (Dallas, Tex. : 1979), 1996, Volume: 27, Issue:6

    Topics: Angiotensin II; Animals; Antihypertensive Agents; Baroreflex; Biphenyl Compounds; Heart Rate; Imidazoles; Losartan; Male; Oligopeptides; Peptide Fragments; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Tetrazoles

1996
Angiotensin II receptors and angiotensin II stimulation of ciliary activity in human fallopian tube.
    The Journal of clinical endocrinology and metabolism, 1996, Volume: 81, Issue:7

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Biphenyl Compounds; Cilia; Fallopian Tubes; Female; Humans; Imidazoles; Immunoenzyme Techniques; Losartan; Oligopeptides; Pregnancy; Premenopause; Receptors, Angiotensin; Tetrazoles; Tissue Distribution

1996
Angiotensin II type 2 receptor-mediated regulation of rat neuronal K+ channels.
    Circulation research, 1996, Volume: 79, Issue:2

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Cells, Cultured; Imidazoles; Kinetics; Losartan; Neurons; Oligopeptides; Patch-Clamp Techniques; Potassium Channels; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin; Tetrazoles

1996
The contribution of AT1 and AT2 angiotensin receptors to its cognitive effects.
    Acta neurobiologiae experimentalis, 1996, Volume: 56, Issue:1

    Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Biphenyl Compounds; Cognition; Imidazoles; Losartan; Oligopeptides; Rats; Receptors, Angiotensin; Tetrazoles

1996
Angiotensin II receptor expression in the conduction system and arterial duct of neonatal and adult rat hearts.
    Regulatory peptides, 1996, May-07, Volume: 63, Issue:1

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Animals, Newborn; Atrioventricular Node; Autoradiography; Binding Sites; Biphenyl Compounds; Female; Imidazoles; Iodine Radioisotopes; Losartan; Male; Oligopeptides; Pregnancy; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin; Tetrazoles

1996
Potentiation of purinergic transmission by angiotensin in prostatic rat vas deferens.
    British journal of pharmacology, 1996, Volume: 118, Issue:6

    Topics: Adrenergic Uptake Inhibitors; Angiotensin I; Angiotensin II; Animals; Biphenyl Compounds; Electric Stimulation; Imidazoles; In Vitro Techniques; Losartan; Male; Muscle Contraction; Norepinephrine; Oligopeptides; Prostate; Protease Inhibitors; Purinergic P2 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P2; Reserpine; Synaptic Transmission; Tetrazoles; Vas Deferens

1996
The role of brain angiotensin in thirst and AVP release induced by hemorrhage.
    Regulatory peptides, 1996, Oct-08, Volume: 66, Issue:1-2

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Biphenyl Compounds; Blood Pressure; Blood Volume; Captopril; Cohort Studies; Colony-Stimulating Factors; Drinking; Hemorrhage; Hypothalamus; Imidazoles; Injections, Intraperitoneal; Injections, Intraventricular; Losartan; Male; Oligopeptides; Radioimmunoassay; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin; Recombinant Proteins; Tetrazoles; Thirst; Time Factors; Vasopressins

1996
Effect of brain angiotensin II AT1, AT2, and cholinergic receptor antagonism on drinking in water-deprived rats.
    Regulatory peptides, 1996, Oct-08, Volume: 66, Issue:1-2

    Topics: Angiotensin Receptor Antagonists; Animals; Atropine; Biphenyl Compounds; Cholinergic Antagonists; Colony-Stimulating Factors; Dose-Response Relationship, Drug; Drinking; Imidazoles; Injections, Intraventricular; Losartan; Male; Muscarinic Antagonists; Oligopeptides; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptors, Angiotensin; Receptors, Cholinergic; Receptors, Neurotransmitter; Recombinant Proteins; Tetrazoles; Thirst; Time Factors; Water Deprivation

1996
The angiotensin II type 2 receptor primarily inhibits cell growth via pertussis toxin-sensitive G proteins.
    Biochemical and biophysical research communications, 1996, Nov-12, Volume: 228, Issue:2

    Topics: 3T3 Cells; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Binding, Competitive; Biphenyl Compounds; Cell Division; GTP-Binding Proteins; Imidazoles; Kinetics; Losartan; Mice; Oligopeptides; Pertussis Toxin; Rats; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Recombinant Proteins; Tetrazoles; Transfection; Virulence Factors, Bordetella

1996
Regulation of angiotensin II receptor AT1 subtypes in renal afferent arterioles during chronic changes in sodium diet.
    The Journal of clinical investigation, 1997, Mar-01, Volume: 99, Issue:5

    Topics: Actins; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Biphenyl Compounds; Cloning, Molecular; Culture Techniques; DNA, Complementary; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Enalaprilat; Gene Expression Regulation; Imidazoles; Kidney; Losartan; Male; Oligopeptides; Polymerase Chain Reaction; Pyridines; Rats; Rats, Wistar; Receptors, Angiotensin; Renal Artery; Renal Circulation; Ribonucleases; RNA, Messenger; Sodium, Dietary; Tetrazoles; Vasoconstrictor Agents

1997
Cardiovascular effects produced by microinjection of angiotensins and angiotensin antagonists into the ventrolateral medulla of freely moving rats.
    Brain research, 1997, Mar-07, Volume: 750, Issue:1-2

    Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Blood Pressure; Heart Rate; Imidazoles; Losartan; Male; Medulla Oblongata; Microinjections; Oligopeptides; Peptide Fragments; Rats; Rats, Wistar; Tetrazoles; Time Factors

1997
Cloning and expression of angiotensin II type 2 (AT2) receptors from murine neuroblastoma N1E-115 cells: evidence for AT2 receptor heterogeneity.
    Brain research. Molecular brain research, 1997, Volume: 45, Issue:1

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Cell Membrane; Cloning, Molecular; COS Cells; Dithiothreitol; DNA, Complementary; Imidazoles; Locus Coeruleus; Losartan; Mice; Neuroblastoma; Oligopeptides; Olivary Nucleus; Polymerase Chain Reaction; Pyridines; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Recombinant Proteins; Tetrazoles; Transfection; Tumor Cells, Cultured

1997
Angiotensin II type 1 receptor expression in human breast tissues.
    British journal of cancer, 1997, Volume: 75, Issue:9

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Antibodies, Monoclonal; Antihypertensive Agents; Binding Sites; Binding, Competitive; Biphenyl Compounds; Breast; Breast Neoplasms; Electrophoresis, Polyacrylamide Gel; Female; Humans; Imidazoles; Immunohistochemistry; Losartan; Oligopeptides; Receptors, Angiotensin; Tetrazoles

1997
Type 1 angiotensin II receptors in human endometrium.
    Molecular human reproduction, 1996, Volume: 2, Issue:9

    Topics: Adult; Antibodies, Monoclonal; Binding, Competitive; Biphenyl Compounds; Endometrium; Female; Follicular Phase; Humans; Imidazoles; Immunoblotting; Immunohistochemistry; In Vitro Techniques; Kinetics; Ligands; Losartan; Luteal Phase; Middle Aged; Molecular Weight; Myometrium; Oligopeptides; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Tetrazoles

1996
Distribution and functional significance of angiotensin-II AT1- and AT2-receptor subtypes in the rat adrenal gland.
    Endocrine research, 1998, Volume: 24, Issue:1

    Topics: Adrenal Glands; Aldosterone; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Autoradiography; Catecholamines; Imidazoles; Iodine Radioisotopes; Losartan; Male; Oligopeptides; Osmolar Concentration; Pyridines; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin

1998
Characterization and distribution of angiotensin II receptor subtypes in the mouse brain.
    European journal of pharmacology, 1998, May-01, Volume: 348, Issue:1

    Topics: Angiotensin II; Animals; Autoradiography; Binding, Competitive; Brain Chemistry; Caudate Nucleus; Imidazoles; In Vitro Techniques; Kinetics; Ligands; Locus Coeruleus; Losartan; Male; Mice; Mice, Inbred C57BL; Oligopeptides; Pyridines; Rats; Receptors, Angiotensin

1998
Regulation of jejunal sodium and water absorption by angiotensin subtype receptors.
    The American journal of physiology, 1998, Volume: 275, Issue:2

    Topics: Adrenergic alpha-1 Receptor Antagonists; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Cyclic AMP; Cyclic GMP; Diet, Sodium-Restricted; Dinoprostone; Dose-Response Relationship, Drug; Guanethidine; Homeostasis; Imidazoles; Intestinal Absorption; Intestinal Mucosa; Jejunum; Kinetics; Losartan; Male; Mesenteric Arteries; Oligopeptides; Prazosin; Pyridines; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Time Factors; Water

1998
Angiotensin II receptors on colorectal carcinoma cells.
    International journal of molecular medicine, 1998, Volume: 2, Issue:5

    Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Cell Line, Tumor; Cell Membrane; Colorectal Neoplasms; Humans; Iodine Radioisotopes; Losartan; Oligopeptides; Receptor, Angiotensin, Type 2

1998
Modulation of AT1 receptor-mediated contraction of rat uterine artery by AT2 receptors.
    British journal of pharmacology, 1998, Volume: 125, Issue:7

    Topics: Angiotensin II; Animals; Arteries; Female; Imidazoles; Losartan; Oligopeptides; Phenylephrine; Pregnancy; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Uterus; Vasoconstriction

1998
Effect of luminal angiotensin II receptor antagonists on proximal tubule transport.
    American journal of hypertension, 1999, Volume: 12, Issue:5

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Imidazoles; Ion Transport; Kidney Tubules, Proximal; Losartan; Male; Oligopeptides; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Sodium

1999
Characterization of a functional AT1A angiotensin receptor in pancreatoma AR4-2J cells.
    Peptides, 1999, Volume: 20, Issue:7

    Topics: Amylases; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Base Sequence; Cell Line; DNA Primers; Inositol Phosphates; Kinetics; Losartan; Oligopeptides; Pancreas; Rats; Receptor, Angiotensin, Type 1; Receptors, Angiotensin; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger

1999
Activation of the AT(2) receptor of angiotensin II induces neurite outgrowth and cell migration in microexplant cultures of the cerebellum.
    The Journal of biological chemistry, 1999, Oct-29, Volume: 274, Issue:44

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Blotting, Western; Cell Differentiation; Cell Movement; Cerebellum; Culture Techniques; Fluorescent Antibody Technique, Indirect; Imidazoles; Losartan; Microtubule-Associated Proteins; Neurites; Oligopeptides; Pyridines; Rats; Rats, Long-Evans; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Signal Transduction; tau Proteins; Tubulin

1999
Renal effects of angiotensin II receptor subtype 1 and 2-selective ligands injected into the paraventricular nucleus of conscious rats.
    Regulatory peptides, 1999, Oct-22, Volume: 84, Issue:1-3

    Topics: Angiotensin II; Animals; Injections, Intraventricular; Kidney; Ligands; Losartan; Male; Oligopeptides; Paraventricular Hypothalamic Nucleus; Potassium; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin; Saralasin; Sodium

1999
Pharmacological characterization of KR-30988, a novel non-peptide AT1 receptor antagonist, in rat, rabbit and dog.
    The Journal of pharmacy and pharmacology, 1999, Volume: 51, Issue:10

    Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Aorta; Dogs; Furosemide; Hypertension, Renal; Imidazoles; Losartan; Male; Oligopeptides; Pressoreceptors; Rabbits; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Recombinant Proteins; Tetrazoles; Vasoconstriction

1999
Renal vascular reactivity in mice: AngII-induced vasoconstriction in AT1A receptor null mice.
    Journal of the American Society of Nephrology : JASN, 1999, Volume: 10, Issue:12

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Female; Imidazoles; Losartan; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Oligopeptides; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Renal Circulation; Renin; Vasoconstriction

1999
Angiotensin AT1 receptors in the preoptic area negatively modulate the cardiovascular and ACTH responses induced in rats by intrapreoptic injection of prostaglandin E2.
    Brain research, 2000, Jan-03, Volume: 852, Issue:1

    Topics: Adrenocorticotropic Hormone; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Blood Pressure; Cardiovascular System; Dinoprostone; Injections; Losartan; Male; Oligopeptides; Preoptic Area; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin

2000
Modulation of angiotensin II receptor expression during development and regression of hypoxic pulmonary hypertension.
    American journal of respiratory cell and molecular biology, 2000, Volume: 22, Issue:3

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Antihypertensive Agents; Gene Expression Regulation, Developmental; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Hypoxia; Imidazoles; Iodine Radioisotopes; Ligands; Losartan; Male; Muscle, Smooth, Vascular; Oligopeptides; Oxygen; Pulmonary Alveoli; Pulmonary Artery; Pyridines; Radioligand Assay; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Vasoconstrictor Agents

2000
Angiotensin II type 2 receptors stimulate collagen synthesis in cultured vascular smooth muscle cells.
    Hypertension (Dallas, Tex. : 1979), 2000, Volume: 36, Issue:5

    Topics: Animals; Cells, Cultured; Collagen; Extracellular Matrix; Fibroblasts; Losartan; Male; Mitogen-Activated Protein Kinase 1; Muscle, Smooth, Vascular; Oligonucleotides, Antisense; Oligopeptides; Protein-Tyrosine Kinases; Rats; Rats, Wistar; Receptors, Angiotensin; Thionucleotides

2000
Intracellular Angiotensin II and cell growth of vascular smooth muscle cells.
    British journal of pharmacology, 2001, Volume: 132, Issue:7

    Topics: Androstadienes; Angiotensin II; Animals; Cell Count; Cell Division; Dose-Response Relationship, Drug; Imidazoles; Liposomes; Losartan; Muscle, Smooth, Vascular; Oligopeptides; Pyridines; Thymidine; Wortmannin

2001
Identification of angiotensin II type 2 (AT2) receptor domains mediating high-affinity CGP 42112A binding and receptor activation.
    The Journal of pharmacology and experimental therapeutics, 2001, Volume: 298, Issue:2

    Topics: Animals; Anti-Arrhythmia Agents; COS Cells; DNA, Complementary; Imidazoles; Inosine Triphosphate; Losartan; Mutagenesis; Oligopeptides; Pyridines; Radioligand Assay; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Recombinant Fusion Proteins; Thermodynamics; Transfection

2001
Differential regulation of thrombospondin-1 and fibronectin by angiotensin II receptor subtypes in cultured endothelial cells.
    Cardiovascular research, 2001, Volume: 51, Issue:4

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Aorta; Arteriosclerosis; Blotting, Northern; Cattle; Cell Division; Cells, Cultured; DNA; Dose-Response Relationship, Drug; Endothelium, Vascular; Fibronectins; Imidazoles; Losartan; Male; Oligopeptides; Pyridines; Rats; Rats, Wistar; Receptors, Angiotensin; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Thrombospondin 1

2001
Angiotensin II type AT(2) receptor mRNA expression and renal vasodilatation are increased in renal failure.
    Hypertension (Dallas, Tex. : 1979), 2001, Volume: 38, Issue:3 Pt 2

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; 5,8,11,14-Eicosatetraynoic Acid; Angiotensin II; Animals; Antihypertensive Agents; Arachidonic Acid; Clotrimazole; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Gene Expression Regulation; Imidazoles; In Vitro Techniques; Indomethacin; Kidney; Losartan; Male; NG-Nitroarginine Methyl Ester; Oligopeptides; Pyridines; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Renal Insufficiency; RNA, Messenger; Vasodilation

2001
Angiotensin II enhances noradrenaline release from sympathetic nerves of the rat prostate via a novel angiotensin receptor: implications for the pathophysiology of benign prostatic hyperplasia.
    The Journal of endocrinology, 2001, Volume: 171, Issue:1

    Topics: Analysis of Variance; Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Bradykinin; Captopril; CHO Cells; Cricetinae; Dose-Response Relationship, Drug; Imidazoles; Losartan; Male; Norepinephrine; Oligopeptides; Prostate; Prostatic Hyperplasia; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin; Sympathetic Nervous System; Synaptic Transmission

2001
Angiotensin type 2 receptor-mediated hypotension in angiotensin type-1 receptor-blocked rats.
    Hypertension (Dallas, Tex. : 1979), 2001, Dec-01, Volume: 38, Issue:6

    Topics: Angiotensin Receptor Antagonists; Animals; Blood Pressure Determination; Diet, Sodium-Restricted; Hypotension; Losartan; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Oligopeptides; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Tetrazoles; Valine; Valsartan; Vasodilation

2001
Effects of angiotensin II microinjected into medial amygdala on male sexual behavior in rats.
    Hormones and behavior, 2002, Volume: 41, Issue:3

    Topics: Amygdala; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Losartan; Male; Microinjections; Oligopeptides; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Sexual Behavior, Animal; Vasoconstrictor Agents

2002
Angiotensin II stimulation of Na+/K+ATPase activity and cell growth by calcium-independent pathway in MCF-7 breast cancer cells.
    The Journal of endocrinology, 2002, Volume: 173, Issue:2

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Breast Neoplasms; Cell Division; Dose-Response Relationship, Drug; Enzyme Inhibitors; Epithelial Cells; Female; Gene Expression; Humans; Losartan; Oligopeptides; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Reverse Transcriptase Polymerase Chain Reaction; Sodium-Potassium-Exchanging ATPase; Stimulation, Chemical; Tumor Cells, Cultured

2002
Binding of KRH-594, an antagonist of the angiotensin II type 1 receptor, to cloned human and rat angiotensin II receptors.
    Fundamental & clinical pharmacology, 2002, Volume: 16, Issue:4

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Benzimidazoles; Biphenyl Compounds; Chlorocebus aethiops; COS Cells; Dose-Response Relationship, Drug; Humans; Imidazoles; In Vitro Techniques; Liver; Losartan; Membranes; Oligopeptides; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Tetrazoles; Thiadiazoles; Time Factors; Transfection

2002
Localization of AT(2) receptors in the nucleus of the solitary tract of spontaneously hypertensive and Wistar Kyoto rats using [125I] CGP42112: upregulation of a non-angiotensin II binding site following unilateral nodose ganglionectomy.
    Brain research, 2003, Apr-04, Volume: 968, Issue:1

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Autoradiography; Binding, Competitive; Brain; Dose-Response Relationship, Drug; Functional Laterality; Ganglionectomy; Imidazoles; Immunohistochemistry; Iodine Radioisotopes; Losartan; Male; Nodose Ganglion; Oligopeptides; Pyridines; Radioligand Assay; Radiopharmaceuticals; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Angiotensin; Solitary Nucleus

2003
Angiotensin II and III microinjections into the zona incerta influence drinking behavior.
    Brain research, 2003, Jul-11, Volume: 977, Issue:2

    Topics: Angiotensin II; Angiotensin III; Animals; Antihypertensive Agents; Dose-Response Relationship, Drug; Drinking; Drinking Behavior; Drug Interactions; Imidazoles; Losartan; Male; Microinjections; Oligopeptides; Pyridines; Rats; Subthalamus; Time Factors

2003
Angiotensin II type 2 receptor inhibits vascular endothelial growth factor-induced migration and in vitro tube formation of human endothelial cells.
    Circulation research, 2003, Sep-05, Volume: 93, Issue:5

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Apoptosis; Blotting, Western; Cell Line; Cell Movement; Cells, Cultured; Dose-Response Relationship, Drug; Endothelial Growth Factors; Endothelium, Vascular; Humans; Imidazoles; Intercellular Signaling Peptides and Proteins; Losartan; Lymphokines; Neovascularization, Physiologic; Oligopeptides; Pertussis Toxin; Phosphorylation; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Signal Transduction; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor Receptor-2; Vascular Endothelial Growth Factors

2003
Effects of V1 and angiotensin receptor subtypes of the paraventricular nucleus on the water intake induced by vasopressin injected into the lateral septal area.
    Brain research bulletin, 2003, Sep-30, Volume: 61, Issue:5

    Topics: Animals; Arginine Vasopressin; Dose-Response Relationship, Drug; Drinking; Drug Synergism; Losartan; Male; Neural Pathways; Oligopeptides; Paraventricular Hypothalamic Nucleus; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptors, Angiotensin; Receptors, Vasopressin; Septum of Brain; Vasopressins; Water Deprivation

2003
Effects of subtypes of adrenergic and angiotensinergic antagonists on the water and sodium intake induced by adrenaline injected into the paraventricular nucleus.
    Brain research, 2003, Dec-24, Volume: 994, Issue:2

    Topics: Adrenergic alpha-Antagonists; Angiotensin Receptor Antagonists; Animals; Behavior, Animal; Diuretics; Dose-Response Relationship, Drug; Drinking; Epinephrine; Feeding Behavior; Furosemide; Losartan; Male; Oligopeptides; Paraventricular Hypothalamic Nucleus; Piperazines; Quinazolines; Quinoxalines; Rats; Rats, Sprague-Dawley; Sodium Chloride, Dietary

2003
Effects of angiotensin and vasopressin V(1) receptors on water and sodium intake induced by injection of vasopressin into lateral septal area.
    Regulatory peptides, 2004, May-15, Volume: 118, Issue:3

    Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Angiotensin Receptor Antagonists; Animals; Antidiuretic Hormone Receptor Antagonists; Arginine Vasopressin; Dose-Response Relationship, Drug; Drinking; Histocytochemistry; Losartan; Male; Oligopeptides; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Receptors, Vasopressin; Septum of Brain; Sodium; Sodium Chloride, Dietary; Water-Electrolyte Balance

2004
Influence of arginine vasopressin receptors and angiotensin receptor subtypes on the water intake and arterial blood pressure induced by vasopressin injected into the lateral septal area of the rat.
    Autonomic neuroscience : basic & clinical, 2004, Mar-31, Volume: 111, Issue:1

    Topics: Animals; Antidiuretic Hormone Receptor Antagonists; Antihypertensive Agents; Blood Pressure; Dose-Response Relationship, Drug; Drinking; Injections, Intraventricular; Losartan; Male; Oligopeptides; Rats; Receptors, Angiotensin; Septum of Brain; Vasoconstrictor Agents; Vasopressins

2004
A new role for the renin-angiotensin system in the rat periaqueductal gray matter: angiotensin receptor-mediated modulation of nociception.
    Neuroscience, 2005, Volume: 132, Issue:2

    Topics: Anesthetics, Local; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Dose-Response Relationship, Drug; Immunohistochemistry; Lidocaine; Losartan; Male; Nociceptors; Oligopeptides; Pain Measurement; Periaqueductal Gray; Rats; Rats, Wistar; Reaction Time; Receptors, Angiotensin; Renin-Angiotensin System; Time Factors

2005
Interaction between arginine vasopressin and angiotensin II receptors in the central regulation of sodium balance.
    Regulatory peptides, 2005, Dec-15, Volume: 132, Issue:1-3

    Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin Receptor Antagonists; Animals; Arginine Vasopressin; Blood Pressure; Dose-Response Relationship, Drug; Hypothalamus; Injections, Intraventricular; Losartan; Male; Oligopeptides; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin; Receptors, Vasopressin; Sodium

2005
Reversal of fructose-induced hypertension and insulin resistance by chronic losartan treatment is independent of AT2 receptor activation in rats.
    Journal of hypertension, 2005, Volume: 23, Issue:12

    Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Animals; Antihypertensive Agents; Fructose; Glucose; Glucose Clamp Technique; Hypertension; Imidazoles; Insulin Resistance; Liver; Losartan; Male; Oligopeptides; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 2

2005
Vasopressin and angiotensin receptors of the medial septal area of the brain in the control of thirst and salt appetite induced by vasopressin in water-deprived and sodium-depleted rats.
    Pharmacology, biochemistry, and behavior, 2007, Volume: 87, Issue:4

    Topics: Animals; Appetite; Brain Chemistry; Diuretics; Drinking; Electrodes, Implanted; Furosemide; Losartan; Oligopeptides; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Receptors, Vasopressin; Septum of Brain; Sodium; Sodium Chloride, Dietary; Thirst; Vasopressins; Water Deprivation

2007
Angiotensin II type 2 receptor-mediated inhibition of norepinephrine release in isolated rat hearts.
    Journal of cardiovascular pharmacology, 2008, Volume: 52, Issue:2

    Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Animals; Bradykinin; Heart; Imidazoles; In Vitro Techniques; Losartan; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Norepinephrine; Oligopeptides; Phenylalanine; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Sympathetic Nervous System; Tranexamic Acid; Vasoconstrictor Agents

2008
Increased vascular angiotensin type 2 receptor expression and NOS-mediated mechanisms of vascular relaxation in pregnant rats.
    American journal of physiology. Heart and circulatory physiology, 2009, Volume: 296, Issue:3

    Topics: Acetylcholine; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Aorta; Blood Pressure; Dose-Response Relationship, Drug; Endothelium, Vascular; Female; Imidazoles; Losartan; Muscle, Smooth, Vascular; Nitric Oxide; Nitric Oxide Synthase Type III; Oligopeptides; Phenylephrine; Phosphorylation; Pregnancy; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; RNA, Messenger; Up-Regulation; Vasoconstriction; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents

2009
Angiotensin III modulates the nociceptive control mediated by the periaqueductal gray matter.
    Neuroscience, 2009, Dec-15, Volume: 164, Issue:3

    Topics: Analgesics; Angiotensin II; Angiotensin III; Angiotensin Receptor Antagonists; Animals; Disease Models, Animal; Drug Interactions; Efferent Pathways; Glutamyl Aminopeptidase; Losartan; Male; Microinjections; Neural Inhibition; Nociceptors; Oligopeptides; Pain; Pain Measurement; Pain Threshold; Peptides; Periaqueductal Gray; Rats; Rats, Wistar; Receptors, Angiotensin

2009
Angiotensin II type 2 receptor-dependent increase in nitric oxide synthase activity in the endothelium of db/db mice is mediated via a MEK pathway.
    Pharmacological research, 2012, Volume: 66, Issue:1

    Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Aorta; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Disease Models, Animal; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Activation; Flavonoids; Losartan; Male; MAP Kinase Kinase 1; MAP Kinase Kinase 2; MAP Kinase Kinase Kinases; Mice; Mice, Inbred C57BL; Nitric Oxide; Nitric Oxide Synthase Type III; Oligopeptides; Phosphorylation; Protein Kinase Inhibitors; Receptor, Angiotensin, Type 2; Signal Transduction; Time Factors; Vasodilation; Vasodilator Agents

2012
Angiotensin-(3-4) counteracts the Angiotensin II inhibitory action on renal Ca2+-ATPase through a cAMP/PKA pathway.
    Regulatory peptides, 2012, Aug-20, Volume: 177, Issue:1-3

    Topics: Allosteric Regulation; Angiotensin II; Angiotensin II Type 2 Receptor Blockers; Animals; Binding, Competitive; Calcium-Transporting ATPases; Cell Membrane; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Enzyme Assays; HEK293 Cells; Humans; Imidazoles; Immunoprecipitation; Kidney Tubules, Proximal; Losartan; Oligopeptides; Phosphorylation; Protein Binding; Protein Conformation; Pyridines; Receptor, Angiotensin, Type 2; Sheep; Signal Transduction; Transfection

2012
Angiotensin II type 2 receptor-mediated inhibition of NaCl absorption is blunted in thick ascending limbs from Dahl salt-sensitive rats.
    Hypertension (Dallas, Tex. : 1979), 2012, Volume: 60, Issue:3

    Topics: Absorption; Angiotensin II Type 2 Receptor Blockers; Animals; Disease Models, Animal; Hypertension; Imidazoles; Loop of Henle; Losartan; Male; Nitric Oxide; Oligopeptides; Pyridines; Rats; Rats, Inbred Dahl; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 2; Signal Transduction; Sodium Chloride; Sodium-Potassium-Chloride Symporters; Solute Carrier Family 12, Member 1

2012
Role of angiotensin AT2 receptors and nitric oxide in the cardiopulmonary baroreflex control of renal sympathetic nerve activity in rats.
    Journal of hypertension, 2013, Volume: 31, Issue:9

    Topics: Angiotensin II; Angiotensin II Type 2 Receptor Blockers; Animals; Baroreflex; Blood Pressure; Enzyme Inhibitors; Imidazoles; Kidney; Losartan; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Oligopeptides; Pyridines; Rats; Rats, Wistar; Receptor, Angiotensin, Type 2; Sympathetic Nervous System

2013
Angiotensin AT2 receptor agonist stimulates high stretch induced- ANP secretion via PI3K/NO/sGC/PKG/pathway.
    Peptides, 2013, Volume: 47

    Topics: Angiotensin II; Animals; Atrial Natriuretic Factor; Atrial Pressure; Cyclic GMP-Dependent Protein Kinases; Gene Expression Regulation; Guanylate Cyclase; Heart Atria; Hypertension, Renal; Imidazoles; Losartan; Male; Nitric Oxide; Oligopeptides; Peptide Fragments; Phosphatidylinositol 3-Kinases; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 2; Receptors, Cytoplasmic and Nuclear; Signal Transduction; Soluble Guanylyl Cyclase; Tissue Culture Techniques; Vasodilator Agents

2013
Angiotensin II type 2 receptor correlates with therapeutic effects of losartan in rats with adjuvant-induced arthritis.
    Journal of cellular and molecular medicine, 2013, Volume: 17, Issue:12

    Topics: Angiotensin II; Animals; Ankle Joint; Arthritis, Experimental; Cells, Cultured; Chemotaxis; Injections, Intra-Articular; Losartan; Male; Monocytes; Oligopeptides; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Tumor Necrosis Factor-alpha; Up-Regulation; Vascular Endothelial Growth Factor A

2013
Dual targeting of angiotensin receptors (AGTR1 and AGTR2) in epithelial ovarian carcinoma.
    Gynecologic oncology, 2014, Volume: 135, Issue:1

    Topics: Angiotensin II Type 1 Receptor Blockers; Carcinoma, Ovarian Epithelial; Cells, Cultured; Disease Progression; Drug Therapy, Combination; Female; Humans; Losartan; Middle Aged; Molecular Targeted Therapy; Neoplasms, Glandular and Epithelial; Oligopeptides; Ovarian Neoplasms; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2

2014
Activation of upregulated angiotensin II type 2 receptors decreases carotid pulse pressure in rats with suprarenal abdominal aortic coarctation.
    Clinical and experimental hypertension (New York, N.Y. : 1993), 2015, Volume: 37, Issue:4

    Topics: Angiotensin II Type 2 Receptor Blockers; Animals; Aortic Coarctation; Blood Pressure; Blotting, Western; Carotid Arteries; Disease Models, Animal; Gene Expression Regulation; Hypertension; Imidazoles; Losartan; Male; Oligopeptides; Pyridines; Rats; Rats, Wistar; Receptor, Angiotensin, Type 2; Up-Regulation

2015
The role of brain angiotensin II (type 2) receptors and nitric oxide in the renal sympathoinhibitory response to acute volume expansion in conscious rats.
    Journal of hypertension, 2017, Volume: 35, Issue:2

    Topics: Administration, Intravenous; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Animals; Arterial Pressure; Body Fluids; Brain; Enzyme Inhibitors; Heart Rate; Imidazoles; Infusions, Intraventricular; Kidney; Losartan; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Oligopeptides; Pyridines; Rats; Receptor, Angiotensin, Type 2; Sodium Chloride; Sympathetic Nervous System

2017
AT1 and AT2 receptors modulate renal tubular cell necroptosis in angiotensin II-infused renal injury mice.
    Scientific reports, 2019, 12-19, Volume: 9, Issue:1

    Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Animals; Cell Line; Disease Models, Animal; Epithelial Cells; Humans; Imidazoles; Kidney Failure, Chronic; Kidney Tubules; Losartan; Male; Mice; Necroptosis; Oligopeptides; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Signal Transduction

2019