cgp 42112a has been researched along with angiotensin ii in 168 studies
| Studies (cgp 42112a) | Trials (cgp 42112a) | Recent Studies (post-2010) (cgp 42112a) | Studies (angiotensin ii) | Trials (angiotensin ii) | Recent Studies (post-2010) (angiotensin ii) |
|---|---|---|---|---|---|
| 233 | 0 | 35 | 38,152 | 1,089 | 7,413 |
| Protein | Taxonomy | cgp 42112a (IC50) | angiotensin ii (IC50) |
|---|---|---|---|
| Atrial natriuretic peptide receptor 3 | Homo sapiens (human) | 0.002 | |
| Type-1A angiotensin II receptor | Rattus norvegicus (Norway rat) | 0.002 | |
| Type-1B angiotensin II receptor | Rattus norvegicus (Norway rat) | 0.0018 | |
| Type-1 angiotensin II receptor | Homo sapiens (human) | 0.0055 | |
| Type-2 angiotensin II receptor | Rattus norvegicus (Norway rat) | 0.004 | |
| Type-2 angiotensin II receptor | Homo sapiens (human) | 0.0011 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (0.60) | 18.7374 |
| 1990's | 114 (67.86) | 18.2507 |
| 2000's | 43 (25.60) | 29.6817 |
| 2010's | 10 (5.95) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| de Gasparo, M; Kamber, B; Mele, M; Whitebread, S | 1 |
| Ambühl, P; Felix, D; Ferrario, CM; Imboden, H; Khosla, MC | 1 |
| Beresford, MJ; Fitzsimons, JT | 1 |
| Janiak, P; Pillon, A; Prost, JF; Vilaine, JP | 1 |
| Bogdal, Y; Bottari, SP; Deschepper, CF; Obermüller, N; Zahs, KR | 1 |
| Aiyar, N; Edwards, RM; Hill, DT; Keenan, RM; Stack, EJ; Weidley, EF; Weinstock, J | 1 |
| Saavedra, JM; Strömberg, C; Tsutsumi, K; Viswanathan, M | 2 |
| Balla, T; Baukal, AJ; Catt, KJ; Eng, S | 1 |
| Bühlmayer, P; Criscione, L; de Gasparo, M; Herold, P; Kamber, B; Ostermayer, F; Thomann, H; Whitebread, S | 1 |
| Chappell, MC; Diz, DI; Ferrario, CM; Jaiswal, N; Khosla, MC | 1 |
| Bottari, SP; de Gasparo, M; Kamber, B; Taylor, V; Whitebread, SE | 1 |
| Bottari, SP; Culman, J; de Gasparo, M; Gohlke, P; Obermüller, N; Unger, T | 1 |
| Saavedra, JM; Tsutsumi, K | 4 |
| Raizada, MK; Sumners, C; Tang, W; Zelezna, B | 1 |
| Catt, KJ; Ji, H; Sandberg, K | 1 |
| Diz, DI; Ferrario, CM; Jaiswal, N; Khosla, MC; Tallant, EA | 1 |
| Barnes, KL; Felix, D; Ferrario, CM; Imboden, H; Khosla, MC; Montani, B | 1 |
| Diz, DI; Ferrario, CM; Khosla, MC; Tallant, EA | 1 |
| Pfeilschifter, J | 1 |
| de Gasparo, M; Rogg, H; Schmid, A | 1 |
| Bardhan, S; Inagami, T; Kambayashi, Y; Shirai, H; Takahasi, K | 1 |
| Bassenge, E; Busse, R; Hecker, M; Pörsti, I | 1 |
| Bottari, SP; Brechler, V; De Gasparo, M; Levens, NR | 1 |
| Ciuffo, GM; Saavedra, JM | 1 |
| Smith, RD | 1 |
| Dzau, VJ; Horiuchi, M; Mukoyama, M; Nakajima, M; Pratt, RE | 1 |
| Huang, XC; Richards, EM; Sumners, C | 1 |
| Heemskerk, FM; Saavedra, JM | 1 |
| el Ghissassi, M; Nicolaïdis, S; Thornton, SN | 1 |
| Baldi, E; Catalioto, RM; Cioni, A; Finetti, G; Maggi, M; Mancina, R; Renzetti, AR; Serio, M | 1 |
| de Gasparo, M; Levens, NR | 1 |
| Brink, M; Bullock, G; de Gasparo, M; Rogg, H; Whitebread, S | 1 |
| Bottari, SP; Buisson, B; de Gasparo, M; Gallo-Payet, N; Laflamme, L; Payet, MD | 1 |
| Correa, FM; de Oliveira, AM; Saavedra, JM; Viswanathan, M | 1 |
| Smith, RD; Timmermans, PB | 1 |
| Bottari, SP; Metzger, R; Paul, M; Steckelings, UM; Stoll, M; Unger, T | 1 |
| Näveri, L; Saavedra, JM; Strömberg, C | 1 |
| Campagnole-Santos, MJ; Fontes, MA; Guertzenstein, PG; Khosla, MC; Santos, RA; Silva, LC | 1 |
| Lantelme, P; Liu, KL; Lo, M; Sassard, J | 1 |
| Averill, DB; Barnes, KL; Fow, JE | 1 |
| Chiueh, CC; de Oliveira, AM; Saavedra, JM; Viswanathan, M; Wu, RM | 1 |
| Cumin, F; De Gasparo, M; Levens, N; Macari, D; Whitebread, S | 1 |
| de Gasparo, M; De Hertogh, R; Kalenga, MK; Thomas, K | 1 |
| Douglas, JG; Dulin, NO; Ernsberger, P; Suciu, DJ | 1 |
| Janiak, P; Libert, O; Vilaine, JP | 1 |
| Hong, KW; Rhim, BY; Shin, YW; Yoo, SE | 1 |
| Freeman, EJ; Tallant, EA | 1 |
| Barnes, KL; Ferrario, CM; McQueeney, AJ | 1 |
| Cooper, C; Gaa, ST; Lokuta, AJ; Rogers, TB; Wang, HE | 1 |
| Bihoreau, C; Clauser, E; Conchon, S; Corvol, P; Monnot, C; Sirieix, ME | 1 |
| Bertschin, S; Bühler, FR; Crabos, M; Eberhard, M; Erne, P; Evéquoz, D; Rogg, H | 1 |
| Heitsch, H; Linz, W; Schölkens, BA; Wagner, A; Wiemer, G | 1 |
| Correa, FM; de Oliveira, AM; Heemskerk, FM; Saavedra, JM; Viswanathan, M | 1 |
| Hogarty, DC; Phillips, MI; Tran, DN | 1 |
| Barker, S; Jiménez, E; Montiel, M; Vinson, GP | 1 |
| LeBrethon, MC; Ouali, R; Saez, JM | 1 |
| Bensoussan, M; Mitchell, T; Reilly, T; Ronco, PM; Timmermans, PB; Verroust, PJ | 1 |
| Bottari, S; De Gasparo, M; Levens, N; Macari, D; Whitebread, S | 1 |
| Cooney, AS; Fitzsimons, JT | 1 |
| Averill, DB; Ferrario, CM; Khosla, MC; Kumagai, H | 1 |
| Raizada, MK; Richards, EM; Sumners, C; Tang, W | 1 |
| Bottari, SP; Brechler, V; de Gasparo, M; Jones, PW; Levens, NR | 1 |
| Aiyar, N; Edwards, R; Griffin, E; Nambi, P; Samanen, J; Weinstock, J | 1 |
| Heemskerk, FM; Saavedra, JM; Seltzer, A; Zorad, S | 1 |
| Douglas, JG; Ernsberger, P; Hopfer, U; Ke, FC; Madhun, ZT; Zhou, J | 1 |
| Speth, RC | 1 |
| Benarous, R; Kermabon, AY; Lebrethon, MC; Naville, D; Rouer, E; Saez, JM | 1 |
| Heidland, A; Ling, H; Schaefer, L; Schaefer, RM; Schnittler, HJ; Vamvakas, S | 1 |
| Betteridge, LJ; Hughes, AD; Patel, MK; Schachter, M | 1 |
| Bihoreau, C; Clauser, E; Conchon, S; Corvol, P; Curnow, KM; Monnot, C | 1 |
| Cheung, WT; Sum, CS | 1 |
| Coviello, A; Peral de Bruno, M | 1 |
| Campagnole-Santos, MJ; Khosla, M; Oliveira, DR; Santos, GF; Santos, RA | 1 |
| Collingwood, K; Demetroulis, C; Djahanbakhch, O; Mehta, JG; Puddefoot, JR; Saridogan, E; Vinson, GP | 1 |
| Ichiki, T; Inagami, T; Kambayashi, Y | 1 |
| Gelband, CH; Martens, JR; Posner, P; Sumners, C; Wang, D | 1 |
| Braszko, J | 1 |
| Bastien, NR; Ciuffo, GM; Lambert, C; Saavedra, JM | 1 |
| de Oliveira, M; Jöhren, O; Saavedra, JM; Viswanathan, M | 1 |
| Cheung, WT; Sum, CS; Wan, DC | 1 |
| Jöhren, O; Saavedra, JM; Viswanathan, M | 1 |
| Heininger, F; Phillips, MI; Toffolo, S | 1 |
| Miyazaki, H; Murakami, K; Ozawa, Y; Suzuki, Y | 1 |
| Hazon, N; Takei, Y; Tierney, M | 1 |
| Arendshorst, WJ; Chatziantoniou, C; Kurtz, A; Ruan, X; Wagner, C | 1 |
| Inada, Y; Kanehara, H; Kurobe, Y; Miyazaki, M; Nishikawa, K; Song, K; Wada, T | 1 |
| Campagnole-Santos, MJ; Fontes, MA; Khosla, MC; Lopes, OU; Martins Pinge, MC; Naves, V; Santos, RA | 1 |
| Fluharty, SJ; He, P; Hines, J; Reagan, LP; Siemens, IR; Yang, XD; Yee, DK | 1 |
| Brown, CL; Goode, AW; Ho, MM; Inwang, ER; Marsigliante, S; Payne, JG; Puddefoot, JR; Vinson, GP | 1 |
| Bottari, SP; Bourmeyster, N; Chambaz, EM; Defaye, G; Liakos, P | 1 |
| Abe, I; Fujii, K; Fujishima, M; Onaka, U | 1 |
| Braszko, JJ; Karwowska-Polecka, W; Kułakowska, A; Winnicka, MM | 1 |
| Casanova, C; de Gasparo, M; Merabet, L | 1 |
| Dittus, JJ; Gavini, N; Pulakat, L; Tadessee, AS | 1 |
| Andreis, PG; Belloni, AS; Gottardo, G; Macchi, V; Malendowicz, LK; Nussdorfer, GG | 1 |
| Häuser, W; Jöhren, O; Saavedra, JM | 1 |
| Carey, RM; Guerrant, RL; Jin, XH; Siragy, HM; Wang, ZQ | 1 |
| Dubey, RK; Flammer, J; Lüscher, TF | 1 |
| Kucerová, D; Sloncová, E; Sovová, V; Zelezná, B | 1 |
| Davis, EA; Widdop, RE; Zwart, AS | 1 |
| Cui, XL; Douglas, JG; Haithcock, D; Hopfer, U; Jiao, H | 1 |
| Braszko, JJ; Karwowska-Polecka, W; Kułakowska, A | 1 |
| Cooper, S; Pulakat, L; Turner, CA | 1 |
| Baum, M; Quan, A | 1 |
| Cheung, WT; Ho, WK; Ip, TM; Luk, SK; Wan, DC; Yeung, SY; Yiu, AK | 1 |
| Côté, F; Do, TH; Gallo, JM; Gallo-Payet, N; Laflamme, L | 1 |
| de Arruda Camargo, LA; Saad, WA | 1 |
| Briand, R; Lamouche, S; Martineau, D; Yamaguchi, N | 1 |
| Jung, YS; Lee, BH; Lee, SH; Seo, HW; Shin, HS; Yoo, SE | 1 |
| Arendshorst, WJ; Coffman, TM; Oliverio, MI; Ruan, X | 1 |
| Breault, L; Chamoux, E; Gallo-Payet, N; Lehoux, JG | 1 |
| Sakata, Y; Wada, M; Watanabe, T | 1 |
| Ishii, K; Isobe, K; Kawakami, Y; Nakai, T; Nanmoku, T; Takekoshi, K | 1 |
| Cao, Z; Casley, D; Cooper, ME; Cox, A; Dean, R; Forbes, JM; Gilbert, RE; Kelly, DJ; Martinello, P | 1 |
| Cerra, MC; Hazon, N; Takei, Y; Tierney, ML; Tota, B | 1 |
| de Zeeuw, D; Filipeanu, CM; Henning, RH; Nelemans, A | 1 |
| Casselbrant, A; Ewert, S; Fändriks, L; Holm, M; Johansson, B; Pettersson, A | 1 |
| Bonnet, F; Cao, Z; Carey, RM; Casley, D; Cooper, ME | 1 |
| Ishii, K; Isobe, K; Kawakami, Y; Nakai, T; Takekoshi, K | 1 |
| Fischer, JW; Hahn, AW; Stoll, M; Unger, T | 1 |
| Bautista, R; Escalante, B; Hernández, J; Oyekan, A; Sánchez, A | 1 |
| Fabiani, ME; Frauman, AG; Johnston, CI; Sourial, M; Thomas, WG | 1 |
| Breigeiron, MK; Lucion, AB; Morris, M; Sanvitto, GL | 1 |
| Elia, MG; Greco, S; Marsigliante, S; Muscella, A; Storelli, C | 1 |
| Danser, AH; Saxena, PR; Schuijt, MP | 1 |
| Bagby, SP; Corless, CL; LeBard, LS; Luo, Z; Ogden, BE; Speth, RC | 1 |
| Henrion, D; Levy, BI; Matrougui, K; Widdop, RE | 1 |
| Chiba, S; Inada, Y; Nakane, T | 1 |
| Jarrott, B; Lawrence, AJ; Roulston, CL; Widdop, RE | 2 |
| Bagi, EE; Fekete, E; Lénárd, L | 1 |
| Benndorf, R; Böger, RH; Ergün, S; Steenpass, A; Wieland, T | 1 |
| Alvarez, SE; Ciuffo, GM; Fuentes, LB | 1 |
| Cui, TX; Horiuchi, M; Iwai, M; Li, JM; Li, Z; Min, LJ; Nahmias, C; Okumura, M; Shiuchi, T; Wu, L | 1 |
| Hakam, AC; Hussain, T | 2 |
| Martins, AR; Pelegrini-da-Silva, A; Prado, WA | 1 |
| Kim, MP; Wahl, LM; Zhou, M | 1 |
| Alenina, N; Bader, M; Lemos, VS; Santos, RA; Silva, DM; Walther, T | 1 |
| Antunes-Rodrigues, J; Camargo, LA; Guarda, IF; Guarda, RS; Saad, WA | 1 |
| Armstead, WM; Baranov, D | 1 |
| Duvetorp, A; Ewert, S; Fandriks, L; Holm, M; Johansson, B; Sjoberg, T | 1 |
| García-Colunga, J; Miledi, R; Montiel-Herrera, M | 1 |
| Adachi, M; Hirano, T; Ran, J | 1 |
| Adachi, M; Fukui, T; Hirano, T; Kageyama, H; Okada, K; Ran, J; Saito, K | 1 |
| Horiuchi, M; Iwai, M; Iwanami, J; Li, JM; Min, LJ; Mogi, M; Nahmias, C; Tomochika, H; Tsukuda, K | 1 |
| Cripps, MW; Cureton, EL; Curran, B; Ereso, AQ; Ramirez, RM; Sadjadi, J; Victorino, GP | 1 |
| Buikema, H; Morshuis, WJ; Nickenig, G; Plokker, HW; van de Wal, RM; van der Harst, P; van Gilst, WH; van Veldhuisen, DJ; Voors, AA; Wagenaar, LJ; Wassmann, S | 1 |
| Kautiainen, H; Oksala, O; Vaajanen, A; Vapaatalo, H | 1 |
| Akira, T; Egi, Y; Maruyama, T; Matsumura, Y; Ohkita, M; Sasaoka, T; Takaoka, M; Tawa, M; Yamamoto, A | 1 |
| Hongo, S; Kanome, T; Miyazaki, A; Nishio, K; Takahashi, K; Watanabe, T | 1 |
| Falone, AE; Khalil, RA; Koledova, VV; Qiao, X; Stennett, AK | 1 |
| Assunção-Miranda, I; Axelband, F; de Paula, IR; Dias, J; Ferrão, FM; Lara, LS; Miranda, A; Miranda, F; Vieyra, A | 1 |
| Guethe, LM; Juliano, MA; Martins, AR; Pelegrini-da-Silva, A; Prado, WA; Rosa, E | 1 |
| El-Dahr, SS; Garrett, C; Song, R; Spera, M; Yosypiv, IV | 1 |
| Kamata, K; Kobayashi, T; Matsumoto, T; Taguchi, K | 1 |
| Axelband, F; Costa-Neto, CM; Dias, J; Ferrão, FM; Lara, LS; Miranda, F; Reis, RI; Vieyra, A | 1 |
| Abdulla, MH; Johns, EJ | 2 |
| Cha, SA; Gao, S; Kim, SH; Park, BH; Park, BM; Park, WH | 1 |
| Amelio, D; Capria, C; Cerra, MC; Garofalo, F; Imbrogno, S | 1 |
| Chang, Y; Hu, S; Huang, Q; Sun, W; Wang, D; Wang, Q; Wei, W; Wu, J; Wu, Y; Yuan, J; Zhao, W; Zhou, A; Zhu, J | 1 |
| Chen, H; Hu, X; Jiang, Z; Li, J; Liu, X; Steinhoff, G; Wang, L; Xu, Y; Yu, H; Zhang, Z | 1 |
| Cui, H; Liang, H; Lv, J; Wang, H; Wang, M; Wang, S; Ye, F; Zheng, Y; Zhu, Y | 1 |
2 review(s) available for cgp 42112a and angiotensin ii
| Article | Year |
|---|---|
Pharmacology of angiotensin II receptors in the kidney.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Humans; Imidazoles; Kidney; Losartan; Oligopeptides; Pyridines; Rats; Receptors, Angiotensin; Species Specificity; Tetrazoles; Tissue Distribution | 1994 |
Human angiotensin receptor subtypes.
Topics: Angiotensin I; Angiotensin II; Angiotensin III; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; DNA, Complementary; Gene Library; Humans; Imidazoles; Losartan; Oligopeptides; Pyridines; Receptors, Angiotensin; Tetrazoles | 1994 |
166 other study(ies) available for cgp 42112a and angiotensin ii
| Article | Year |
|---|---|
Preliminary biochemical characterization of two angiotensin II receptor subtypes.
Topics: Adrenal Glands; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Binding, Competitive; Biphenyl Compounds; Dithiothreitol; Female; Humans; Imidazoles; Losartan; Muscle, Smooth; Oligopeptides; Rats; Receptors, Angiotensin; Uterus | 1989 |
Effects of angiotensin II and its selective antagonists on inferior olivary neurones.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Autoradiography; Biphenyl Compounds; Imidazoles; Losartan; Neurons; Oligopeptides; Olivary Nucleus; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin; Synaptic Transmission; Tetrazoles | 1992 |
Intracerebroventricular angiotensin II-induced thirst and sodium appetite in rat are blocked by the AT1 receptor antagonist, Losartan (DuP 753), but not by the AT2 antagonist, CGP 42112B.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Appetite; Biphenyl Compounds; Imidazoles; Injections, Intraventricular; Losartan; Male; Oligopeptides; Rats; Rats, Wistar; Sodium, Dietary; Tetrazoles; Thirst | 1992 |
Role of angiotensin subtype 2 receptor in neointima formation after vascular injury.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Biphenyl Compounds; Carotid Arteries; Carotid Artery Injuries; Catheterization; Hyperplasia; Imidazoles; Indoles; Losartan; Male; Oligopeptides; Perindopril; Rats; Rats, Wistar; Receptors, Angiotensin; Tetrazoles; Tunica Intima | 1992 |
Characterization and distribution of angiotensin II binding sites in fetal and neonatal astrocytes from different rat brain regions.
Topics: Angiotensin II; Animals; Animals, Newborn; Astrocytes; Binding Sites; Binding, Competitive; Biphenyl Compounds; Brain; Cells, Cultured; Fetus; Imidazoles; Losartan; Oligopeptides; Rats; Saralasin; Tetrazoles; Tissue Distribution | 1992 |
Characterization of renal angiotensin II receptors using subtype selective antagonists.
Topics: Acrylates; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Binding, Competitive; Biphenyl Compounds; Dithiothreitol; Guanylyl Imidodiphosphate; Imidazoles; In Vitro Techniques; Kidney; Losartan; Oligopeptides; Pyridines; Rats; Rats, Inbred Strains; Receptors, Angiotensin; Tetrazoles; Thiophenes | 1992 |
Angiotensin-II receptor subtypes in fetal tissue of the rat: autoradiography, guanine nucleotide sensitivity, and association with phosphoinositide hydrolysis.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Autoradiography; Binding, Competitive; Fetus; Gestational Age; Guanine Nucleotides; Guanosine 5'-O-(3-Thiotriphosphate); Hydrolysis; Imidazoles; Losartan; Oligopeptides; Phosphatidylinositols; Pyridines; Rats; Rats, Inbred Strains; Receptors, Angiotensin; Tetrazoles; Tissue Distribution | 1991 |
Angiotensin II receptor subtypes and biological responses in the adrenal cortex and medulla.
Topics: Adrenal Cortex; Adrenal Medulla; Aldosterone; Angiotensin II; Animals; Binding Sites; Biphenyl Compounds; Cattle; Cyclic AMP; Imidazoles; In Vitro Techniques; Losartan; Oligopeptides; Rats; Rats, Inbred Strains; Receptors, Angiotensin; Tetrazoles; Zona Glomerulosa | 1991 |
Binding characteristics and vascular effects of various angiotensin II antagonists.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensins; Animals; Aorta; Biphenyl Compounds; Dose-Response Relationship, Drug; Female; Humans; Imidazoles; In Vitro Techniques; Ligands; Losartan; Muscle, Smooth, Vascular; Oligopeptides; Rabbits; Rats; Receptors, Angiotensin; Saralasin; Uterus | 1990 |
Type-1 and type-2 angiotensin II receptors in fetal rat brain.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Autoradiography; Biphenyl Compounds; Brain; Female; Fetus; Imidazoles; Iodine Radioisotopes; Losartan; Oligopeptides; Pregnancy; Rats; Rats, Inbred Strains; Receptors, Angiotensin; Staining and Labeling; Tetrazoles | 1991 |
Stimulation of endothelial cell prostaglandin production by angiotensin peptides. Characterization of receptors.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Cells, Cultured; Dinoprostone; Endothelium, Vascular; Epoprostenol; Imidazoles; Losartan; Oligopeptides; Prostaglandins; Pyridines; Receptors, Angiotensin; Tetrazoles | 1992 |
Radioiodinated CGP 42112A: a novel high affinity and highly selective ligand for the characterization of angiotensin AT2 receptors.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Binding, Competitive; Cell Membrane; Female; Humans; Iodine Radioisotopes; Kinetics; Molecular Structure; Myometrium; Oligopeptides; Radioligand Assay; Receptors, Angiotensin | 1991 |
Distribution of angiotensin II receptor subtypes in rat brain nuclei.
Topics: Angiotensin II; Animals; Binding, Competitive; Biphenyl Compounds; Brain; Brain Stem; Hypothalamus; Imidazoles; Iodine Radioisotopes; Losartan; Male; Mesencephalon; Oligopeptides; Organ Specificity; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, Angiotensin; Saralasin; Tetrazoles | 1991 |
Characterization and development of angiotensin II receptor subtypes (AT1 and AT2) in rat brain.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Autoradiography; Binding, Competitive; Brain; Imidazoles; Losartan; Male; Oligopeptides; Rats; Rats, Inbred Strains; Receptors, Angiotensin; Tetrazoles; Tissue Distribution | 1991 |
Angiotensin II receptor subtypes are coupled with distinct signal-transduction mechanisms in neurons and astrocytes from rat brain.
Topics: Angiotensin II; Animals; Animals, Newborn; Astrocytes; Binding, Competitive; Biphenyl Compounds; Brain; Cells, Cultured; Imidazoles; Kinetics; Ligands; Losartan; Neurons; Oligopeptides; Pyridines; Rats; Rats, Inbred Strains; Receptors, Angiotensin; Signal Transduction; Tetrazoles | 1991 |
Angiotensin-II receptor subtypes in median eminence and basal forebrain areas involved in regulation of pituitary function.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Autoradiography; Binding, Competitive; Biphenyl Compounds; Cerebral Arteries; Dithiothreitol; Imidazoles; Losartan; Male; Median Eminence; Oligopeptides; Pituitary Gland; Prosencephalon; Pyridines; Rats; Rats, Inbred Strains; Receptors, Angiotensin; Tetrazoles | 1991 |
Differential development of angiotensin II receptor subtypes in the rat brain.
Topics: Aging; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Brain; Imidazoles; Kinetics; Losartan; Male; Oligopeptides; Organ Specificity; Rats; Rats, Inbred Strains; Receptors, Angiotensin; Tetrazoles | 1991 |
Quantitative autoradiography reveals different angiotensin II receptor subtypes in selected rat brain nuclei.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Autoradiography; Binding, Competitive; Brain; Brain Chemistry; Dithiothreitol; Imidazoles; Losartan; Male; Medulla Oblongata; Oligopeptides; Paraventricular Hypothalamic Nucleus; Rats; Rats, Inbred Strains; Receptors, Angiotensin; Subfornical Organ; Tetrazoles; Tissue Distribution | 1991 |
Novel angiotensin II antagonists distinguish amphibian from mammalian angiotensin II receptors expressed in Xenopus laevis oocytes.
Topics: Aequorin; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Cytoplasm; DNA; Female; Ligands; Light; Mammals; Oligopeptides; Oocytes; Rats; Receptors, Angiotensin; Receptors, Muscarinic; RNA, Messenger; Xenopus | 1991 |
Characterization of angiotensin receptors mediating prostaglandin synthesis in C6 glioma cells.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Glioma; Imidazoles; Losartan; Oligopeptides; Peptide Fragments; Prostaglandins; Receptors, Angiotensin; Tetrazoles; Tumor Cells, Cultured | 1991 |
Neurophysiological responses to angiotensin-(1-7).
Topics: Angiotensin I; Angiotensin II; Angiotensin III; Animals; Brain; Electrophysiology; Female; Iontophoresis; Neurons; Oligopeptides; Paraventricular Hypothalamic Nucleus; Peptide Fragments; Rats; Rats, Inbred WKY; Vasopressins | 1991 |
Identification and regulation of angiotensin II receptor subtypes on NG108-15 cells.
Topics: 1-Sarcosine-8-Isoleucine Angiotensin II; Angiotensin II; Angiotensin Receptor Antagonists; Binding, Competitive; Calcium; Hybrid Cells; Imidazoles; Losartan; Neurons; Oligopeptides; Receptors, Angiotensin; Signal Transduction; Tetrazoles; Tumor Cells, Cultured | 1991 |
Angiotensin II B-type receptor mediates phosphoinositide hydrolysis in mesangial cells.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Cells, Cultured; Glomerular Mesangium; Hydrolysis; Imidazoles; Inositol 1,4,5-Trisphosphate; Losartan; Oligopeptides; Phosphatidylinositols; Rats; Receptors, Angiotensin; Stimulation, Chemical | 1990 |
Identification and characterization of angiotensin II receptor subtypes in rabbit ventricular myocardium.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Binding, Competitive; Heart Ventricles; Kinetics; Male; Myocardium; Oligopeptides; Rabbits; Receptors, Angiotensin | 1990 |
Protein tyrosine phosphatase inhibition by angiotensin II in rat pheochromocytoma cells through type 2 receptor, AT2.
Topics: Adrenal Gland Neoplasms; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Cell Membrane; Chromatography, Affinity; Guanosine Diphosphate; Imidazoles; Losartan; Oligopeptides; PC12 Cells; Pertussis Toxin; Pheochromocytoma; Phosphates; Phosphoproteins; Phosphorus Radioisotopes; Phosphotyrosine; Protein Tyrosine Phosphatases; Pyridines; Rats; Receptors, Angiotensin; Tetrazoles; Thionucleotides; Tyrosine; Virulence Factors, Bordetella | 1994 |
Dual action of angiotensin II on coronary resistance in the isolated perfused rabbit heart.
Topics: 6-Ketoprostaglandin F1 alpha; Adenosine; Amino Acid Oxidoreductases; Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Blood Pressure; Coronary Circulation; Coronary Vessels; Cyclooxygenase Inhibitors; Endothelium, Vascular; Heart; In Vitro Techniques; Male; Muscle, Smooth, Vascular; Myocardial Contraction; Nitric Oxide Synthase; Oligopeptides; Organ Size; Quinolines; Rabbits; Receptors, Angiotensin; Vascular Resistance; Vasodilation | 1993 |
Angiotensin AT2 receptor mediated inhibition of particulate guanylate cyclase: a link with protein tyrosine phosphatase stimulation?
Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-GMP Phosphodiesterases; Angiotensin II; Animals; Aorta; Arsenicals; Atrial Natriuretic Factor; Cell Membrane; Cells, Cultured; Cyclic GMP; GTP-Binding Proteins; Guanylate Cyclase; Muscle, Smooth, Vascular; Oligopeptides; PC12 Cells; Protein Tyrosine Phosphatases; Rats; Receptors, Angiotensin; Vanadates | 1994 |
Selective peptide and nonpeptide ligands differentially bind to angiotensin II AT2 receptor and a non-angiotensin II CGP42112 binding site.
Topics: Amino Acid Sequence; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Binding Sites; Female; Ligands; Male; Molecular Sequence Data; Oligopeptides; Pregnancy; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin | 1995 |
Identification of atypical (non-AT1, non-AT2) angiotensin binding sites with high affinity for angiotensin I on IEC-18 rat intestinal epithelial cells.
Topics: 1-Sarcosine-8-Isoleucine Angiotensin II; Angiotensin I; Angiotensin II; Angiotensin III; Angiotensin Receptor Antagonists; Animals; Binding Sites; Binding, Competitive; Biphenyl Compounds; Cell Line; Epithelium; Imidazoles; Intestinal Mucosa; Intestine, Small; Losartan; Oligopeptides; Peptide Fragments; Pyridines; Rats; Receptors, Angiotensin; Tetrazoles | 1995 |
Characterization of a rat type 2 angiotensin II receptor stably expressed in 293 cells.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Arachidonic Acid; Cell Line; DNA, Complementary; Embryo, Mammalian; Gene Expression; GTP-Binding Proteins; Guanine Nucleotides; Humans; Iodine Radioisotopes; Kidney; Oligopeptides; Oxidation-Reduction; Rats; Receptors, Angiotensin; Recombinant Proteins; Transfection | 1995 |
Angiotensin II type 2 receptor-mediated stimulation of protein phosphatase 2A in rat hypothalamic/brainstem neuronal cocultures.
Topics: Angiotensin II; Animals; Brain Stem; Coculture Techniques; Hypothalamus; Neurons; Oligopeptides; Pertussis Toxin; Phosphoprotein Phosphatases; Protein Phosphatase 2; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin; Virulence Factors, Bordetella | 1995 |
Quantitative autoradiography of angiotensin II AT2 receptors with [125I]CGP 42112.
Topics: Adrenal Medulla; Angiotensin II; Animals; Autoradiography; Binding, Competitive; Densitometry; Geniculate Bodies; Image Processing, Computer-Assisted; Iodine Radioisotopes; Male; Oligopeptides; Olivary Nucleus; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin; Saralasin | 1995 |
Angiotensin II-induced thirst, but not sodium appetite, via AT1 receptors in organum cavum prelamina terminalis.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Appetite; Biphenyl Compounds; Dose-Response Relationship, Drug; Imidazoles; Losartan; Male; Microinjections; Oligopeptides; Prosencephalon; Rats; Rats, Wistar; Receptors, Angiotensin; Sodium, Dietary; Tetrazoles; Thirst | 1995 |
Identification and characterization of functional angiotensin II receptors in human neuroblastoma cells.
Topics: 1-Sarcosine-8-Isoleucine Angiotensin II; Angiotensin II; Angiotensin III; Angiotensin Receptor Antagonists; Binding, Competitive; Biphenyl Compounds; Calcium; Cyclic AMP; Dose-Response Relationship, Drug; Humans; Imidazoles; Kinetics; Losartan; Neuroblastoma; Oligopeptides; Pyridines; Receptors, Angiotensin; Tetrazoles; Tumor Cells, Cultured; Vasoactive Intestinal Peptide | 1995 |
Localization of angiotensin II receptor subtypes in the rabbit heart.
Topics: Acetylcholinesterase; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Autoradiography; Biphenyl Compounds; Cell Membrane; Heart Atria; Heart Conduction System; Imidazoles; Immunohistochemistry; Iodine Radioisotopes; Losartan; Male; Myocardium; Oligopeptides; Rabbits; Receptors, Angiotensin; Tetrazoles | 1995 |
A G protein is involved in the angiotensin AT2 receptor inhibition of the T-type calcium current in non-differentiated NG108-15 cells.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Calcium Channels; Cyclic GMP; Glioma; GTP-Binding Proteins; Hybrid Cells; Kinetics; Membrane Potentials; Neuroblastoma; Oligopeptides; Patch-Clamp Techniques; Receptors, Angiotensin; Time Factors | 1995 |
Expression of a novel non-angiotensin II [125I]CGP 42112 binding site in healing wounds of the rat brain.
Topics: Angiotensin II; Animals; Binding Sites; Brain Injuries; Iodine Radioisotopes; Male; Oligopeptides; Radioligand Assay; Rats; Rats, Sprague-Dawley; Wound Healing | 1994 |
The angiotensin AT2-receptor mediates inhibition of cell proliferation in coronary endothelial cells.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Aorta; Base Sequence; Binding, Competitive; Biphenyl Compounds; Cell Division; Cells, Cultured; Coronary Vessels; DNA; DNA Primers; Dose-Response Relationship, Drug; Endothelium, Vascular; Gene Expression; Imidazoles; Kinetics; Losartan; Molecular Sequence Data; Muscle, Smooth, Vascular; Oligopeptides; Polymerase Chain Reaction; Pyridines; Rats; Receptors, Angiotensin; RNA, Messenger; Tetrazoles; Thymidine | 1995 |
Angiotensin II AT1 receptor mediated contraction of the perfused rat cerebral artery.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Cerebral Arteries; Imidazoles; In Vitro Techniques; Losartan; Male; Oligopeptides; Perfusion; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin; Tetrazoles; Vasoconstriction | 1994 |
Evidence that angiotensin-(1-7) plays a role in the central control of blood pressure at the ventro-lateral medulla acting through specific receptors.
Topics: Analysis of Variance; Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Blood Pressure; Imidazoles; Losartan; Male; Medulla Oblongata; Oligopeptides; Peptide Fragments; Rats; Rats, Wistar; Tetrazoles | 1994 |
Subtype 2 of angiotensin II receptors controls pressure-natriuresis in rats.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Blood Pressure; Diuresis; Glomerular Filtration Rate; Imidazoles; Losartan; Male; Natriuresis; Oligopeptides; Perfusion; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin; Renal Circulation; Tetrazoles | 1995 |
Mechanisms of angiotensin-induced hypotension and bradycardia in the medial solitary tract nucleus.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Bradycardia; Cardiovascular System; Glutamates; Glutamic Acid; Hypotension; Imidazoles; Losartan; Male; Medulla Oblongata; Microinjections; Oligopeptides; Rats; Rats, Sprague-Dawley; Tetrazoles; Vagus Nerve | 1994 |
[125I]CGP 42112 reveals a non-angiotensin II binding site in 1-methyl-4-phenylpyridine (MPP+)-induced brain injury.
Topics: 1-Methyl-4-phenylpyridinium; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Autoradiography; Binding Sites; Biphenyl Compounds; Brain; Brain Injuries; Imidazoles; Iodine Radioisotopes; Losartan; Male; Oligopeptides; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin; Substantia Nigra; Tetrazoles | 1994 |
Renal actions of the angiotensin AT2 receptor ligands CGP 42112 and PD 123319 after blockade of the renin-angiotensin system.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Blood Pressure; Enalaprilat; Imidazoles; Kidney; Losartan; Male; Oligopeptides; Pyridines; Rats; Rats, Sprague-Dawley; Renin-Angiotensin System; Tetrazoles; Vascular Resistance | 1994 |
Angiotensin II induces human placental lactogen and pregnancy-specific beta 1-glycoprotein secretion via an angiotensin AT1 receptor.
Topics: Angiotensin II; Biphenyl Compounds; Female; Humans; Imidazoles; Losartan; Oligopeptides; Placenta; Placental Lactogen; Pregnancy; Pregnancy-Specific beta 1-Glycoproteins; Receptors, Angiotensin; Tetrazoles; Trophoblasts | 1994 |
Rabbit renal epithelial angiotensin II receptors.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Binding, Competitive; Biphenyl Compounds; Dithiothreitol; Dose-Response Relationship, Drug; Epithelium; Guanosine 5'-O-(3-Thiotriphosphate); Imidazoles; Iodine Radioisotopes; Kidney Cortex; Kinetics; Losartan; Male; Microvilli; Oligopeptides; Pyridines; Rabbits; Radioligand Assay; Receptors, Angiotensin; Tetrazoles | 1994 |
Role of the renin-angiotensin system in neointima formation after injury in rabbits.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Biphenyl Compounds; Blood Pressure; Bradykinin; Heart Rate; Imidazoles; Indoles; Losartan; Male; Oligopeptides; Perindopril; Rabbits; Receptors, Angiotensin; Renin-Angiotensin System; Tetrazoles; Tunica Intima; Wound Healing | 1994 |
Characterization of PD 121981- and CGP 42112-induced unmasking of low concentration effects of angiotensin II in rabbit abdominal aorta.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Aorta, Abdominal; Biphenyl Compounds; Calcium; Dithiothreitol; Female; Gallic Acid; Imidazoles; Losartan; Male; Nifedipine; Oligopeptides; Pyridines; Rabbits; Tetrazoles; Vasoconstriction | 1994 |
Vascular smooth-muscle cells contain AT1 angiotensin receptors coupled to phospholipase D activation.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Aorta, Thoracic; Biphenyl Compounds; Calcium; Diglycerides; Enzyme Activation; Imidazoles; Kinetics; Losartan; Muscle, Smooth, Vascular; Oligopeptides; Peptide Fragments; Phospholipase D; Rats; Receptors, Angiotensin; Signal Transduction; Tetrazoles | 1994 |
Receptor subtype that mediates the neuronal effects of angiotensin II in the rat dorsal medulla.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Electrophysiology; Glutamates; Glutamic Acid; Imidazoles; In Vitro Techniques; Losartan; Medulla Oblongata; Neurons; Oligopeptides; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin; Tetrazoles | 1993 |
Angiotensin II stimulates the release of phospholipid-derived second messengers through multiple receptor subtypes in heart cells.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Animals, Newborn; Biphenyl Compounds; Cells, Cultured; Cinnamates; Eicosanoids; Heart; Heart Ventricles; Imidazoles; Inositol Phosphates; Kinetics; Lysophosphatidylcholines; Myocardium; Oligopeptides; ortho-Aminobenzoates; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin; Second Messenger Systems; Tetrazoles | 1994 |
Synthetic cDNA encoding the rat AT1a receptor: a useful tool for structure-function relationship analysis.
Topics: Angiotensin II; Angiotensin III; Angiotensin Receptor Antagonists; Animals; Base Sequence; Biphenyl Compounds; CHO Cells; Codon; Cricetinae; DNA, Complementary; Imidazoles; Kinetics; Losartan; Molecular Sequence Data; Mutagenesis, Site-Directed; Oligodeoxyribonucleotides; Oligopeptides; Open Reading Frames; Pyridines; Rats; Receptors, Angiotensin; Restriction Mapping; Saralasin; Signal Transduction; Structure-Activity Relationship; Tetrazoles; Transfection | 1994 |
Identification of AT1 receptors on human platelets and decreased angiotensin II binding in hypertension.
Topics: Adult; Angiotensin II; Angiotensin Receptor Antagonists; Binding, Competitive; Biphenyl Compounds; Blood Platelets; Humans; Hypertension; Imidazoles; In Vitro Techniques; Kinetics; Losartan; Middle Aged; Oligopeptides; Receptors, Angiotensin; Tetrazoles | 1993 |
The possible role of angiotensin II subtype AT2 receptors in endothelial cells and isolated ischemic rat hearts.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Arginine; Bradykinin; Cattle; Cells, Cultured; Cyclic GMP; Endothelium, Vascular; Female; In Vitro Techniques; Male; Myocardial Ischemia; Nitric Oxide; Nitroarginine; Oligopeptides; Rats; Rats, Wistar; Receptors, Angiotensin | 1993 |
Specific, non-angiotensin, [125I]CGP 42112 binding sites in rat spleen macrophages.
Topics: Amino Acid Sequence; Angiotensin II; Animals; Binding Sites; Cytokines; Female; Growth Substances; In Vitro Techniques; Kinetics; Macrophages; Male; Molecular Sequence Data; Oligopeptides; Pregnancy; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin; Spleen | 1994 |
Involvement of angiotensin receptor subtypes in osmotically induced release of vasopressin.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Arginine Vasopressin; Biphenyl Compounds; Imidazoles; Injections, Intraventricular; Losartan; Male; Oligopeptides; Osmolar Concentration; Pyridines; Radioimmunoassay; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin; Saline Solution, Hypertonic; Tetrazoles | 1994 |
Angiotensin II receptor isoforms in the rat adrenal gland: studies with the selective subtype antagonists DuP 753 and CGP42112A.
Topics: Adrenal Glands; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Autoradiography; Binding, Competitive; Biphenyl Compounds; Imidazoles; Iodine Radioisotopes; Isoelectric Focusing; Kinetics; Losartan; Male; Oligopeptides; Rats; Rats, Wistar; Receptors, Angiotensin; Tetrazoles | 1993 |
Identification and characterization of angiotensin-II receptor subtypes in cultured bovine and human adrenal fasciculata cells and PC12W cells.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Autoradiography; Biphenyl Compounds; Cattle; Cells, Cultured; Chemical Phenomena; Chemistry, Physical; Cross-Linking Reagents; Dithiothreitol; Electrophoresis, Polyacrylamide Gel; Humans; Imidazoles; Losartan; Macromolecular Substances; Oligopeptides; PC12 Cells; Receptors, Angiotensin; Tetrazoles; Zona Fasciculata | 1993 |
Immunological reactivity of angiotensin II receptor antagonists: possible implications for receptor binding sites.
Topics: 1-Sarcosine-8-Isoleucine Angiotensin II; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antibodies, Monoclonal; Antihypertensive Agents; Biphenyl Compounds; Imidazoles; In Vitro Techniques; Indicators and Reagents; Iodine Radioisotopes; Losartan; Molecular Conformation; Oligopeptides; Pyridines; Rats; Receptors, Angiotensin; Saralasin; Tetrazoles | 1993 |
Renal actions of the selective angiotensin AT2 receptor ligands CGP 42112B and PD 123319 in the sodium-depleted rat.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Blood Pressure; Diet, Sodium-Restricted; Glomerular Filtration Rate; Imidazoles; Kidney; Losartan; Male; Oligopeptides; Potassium; Pyridines; Radioligand Assay; Rats; Rats, Sprague-Dawley; Renal Circulation; Sodium; Tetrazoles; Vascular Resistance | 1993 |
The effect of the putative AT2 agonist, p-aminophenylalanine6 angiotensin II, on thirst and sodium appetite in rats.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Appetite; Biphenyl Compounds; Drinking; Imidazoles; Injections, Intraventricular; Losartan; Male; Oligopeptides; Peptide Fragments; Pyridines; Rats; Rats, Wistar; Receptors, Angiotensin; Sodium Chloride, Dietary; Tetrazoles; Thirst | 1993 |
Role of nitric oxide and angiotensin II in the regulation of sympathetic nerve activity in spontaneously hypertensive rats.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Arginine; Biphenyl Compounds; Blood Pressure; Dipeptides; Heart Rate; Imidazoles; Lisinopril; Losartan; Male; Nitric Oxide; Oligopeptides; omega-N-Methylarginine; Pressoreceptors; Rats; Rats, Inbred SHR; Reflex; Tetrazoles | 1993 |
Angiotensin II type 2 receptor expression in neuronal cultures from spontaneously hypertensive rat brain.
Topics: Angiotensin II; Animals; Brain Stem; Cells, Cultured; Cyclic GMP; Hypertension; Hypothalamus; Neurons; Oligopeptides; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Angiotensin; Tumor Cells, Cultured | 1993 |
Agonistic and antagonistic properties of angiotensin analogs at the AT2 receptor in PC12W cells.
Topics: 1-Sarcosine-8-Isoleucine Angiotensin II; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Binding, Competitive; Biphenyl Compounds; Cyclic GMP; Imidazoles; Losartan; Oligopeptides; PC12 Cells; Pyridines; Rats; Receptors, Angiotensin; Tetrazoles | 1993 |
Characterization of bovine ovary angiotensin II receptors using subtype-selective antagonists.
Topics: Acrylates; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Binding, Competitive; Cattle; Female; Imidazoles; In Vitro Techniques; Oligopeptides; Ovary; Pyridines; Receptors, Angiotensin; Thiophenes | 1993 |
Characterization of brain angiotensin II AT2 receptor subtype using [125I] CGP 42112A.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Autoradiography; Brain; Female; Geniculate Bodies; Imidazoles; In Vitro Techniques; Oligopeptides; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin | 1993 |
Signal transduction mediated by angiotensin II receptor subtypes expressed in rat renal mesangial cells.
Topics: Adenylyl Cyclase Inhibitors; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Calcium; Cell Division; Cells, Cultured; Glomerular Mesangium; Imidazoles; Losartan; Oligopeptides; Protein Biosynthesis; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin; Signal Transduction; Tetrazoles | 1993 |
[125I]CGP 42112 binding reveals differences between rat brain and adrenal AT2 receptor binding sites.
Topics: 1-Sarcosine-8-Isoleucine Angiotensin II; Adrenal Glands; Analysis of Variance; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Binding, Competitive; Biphenyl Compounds; Brain; Chromatography, High Pressure Liquid; Imidazoles; Losartan; Male; Mercaptoethanol; Oligopeptides; Oxidation-Reduction; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin; Tetrazoles | 1993 |
Characterization and regulation of the angiotensin II type-1 receptor (binding and mRNA) in human adrenal fasciculata-reticularis cells.
Topics: Adult; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Binding, Competitive; Biphenyl Compounds; Cell Line; Cells, Cultured; Cloning, Molecular; Gene Expression Regulation; Homeostasis; Humans; Imidazoles; Kinetics; Losartan; Oligodeoxyribonucleotides; Oligopeptides; Receptors, Angiotensin; RNA, Messenger; Tetrazoles; Transfection; Zona Fasciculata; Zona Reticularis | 1993 |
Angiotensin-II-induced cell hypertrophy: potential role of impaired proteolytic activity in cultured LLC-PK1 cells.
Topics: Analysis of Variance; Angiotensin II; Animals; Biphenyl Compounds; Calcium; Calcium Channel Blockers; Cell Count; Cells, Cultured; Cycloheximide; DNA; Hypertrophy; Imidazoles; Kidney; LLC-PK1 Cells; Losartan; Oligopeptides; Protein Synthesis Inhibitors; Proteins; Swine; Tetrazoles; Verapamil | 1995 |
Angiotensin II receptors are exclusively of the AT1 subtype in cultured human vascular smooth muscle cells.
Topics: 1-Sarcosine-8-Isoleucine Angiotensin II; Angiotensin II; Angiotensin Receptor Antagonists; Binding, Competitive; Biphenyl Compounds; Cells, Cultured; Humans; Imidazoles; Kinetics; Losartan; Muscle, Smooth, Vascular; Oligopeptides; Receptors, Angiotensin; Saralasin; Tetrazoles | 1995 |
Polar residues in the transmembrane domains of the type 1 angiotensin II receptor are required for binding and coupling. Reconstitution of the binding site by co-expression of two deficient mutants.
Topics: Amino Acid Sequence; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Asparagine; Base Sequence; Binding Sites; Biphenyl Compounds; Cell Line; Chlorocebus aethiops; CHO Cells; Cricetinae; DNA Primers; Imidazoles; Inositol Phosphates; Kinetics; Losartan; Molecular Sequence Data; Mutagenesis; Mutagenesis, Site-Directed; Oligodeoxyribonucleotides; Oligopeptides; Point Mutation; Polymerase Chain Reaction; Rats; Receptors, Angiotensin; Recombinant Proteins; Sequence Deletion; Serine; Tetrazoles; Transfection | 1996 |
Characterization of contractile response to angiotensin in epididymal rat vas deferens.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Biphenyl Compounds; Dose-Response Relationship, Drug; Electric Stimulation; Epididymis; Imidazoles; In Vitro Techniques; Losartan; Male; Muscle Contraction; Muscle, Smooth; Oligopeptides; Rats; Rats, Sprague-Dawley; Sympathetic Nervous System; Tetrazoles; Vas Deferens; Vasoconstrictor Agents | 1995 |
Effects of angiotensin II antagonists on the contractile and hydrosmotic effect of AT II and AT III in the toad (Bufo arenarum).
Topics: Analysis of Variance; Angiotensin II; Angiotensin III; Animals; Antihypertensive Agents; Aorta; Biphenyl Compounds; Bufo arenarum; Dose-Response Relationship, Drug; Drug Interactions; Female; Imidazoles; Losartan; Male; Muscle Contraction; Muscle, Smooth, Vascular; Oligopeptides; Osmolar Concentration; Osmosis; Pyridines; Skin; Tetrazoles; Vasoconstrictor Agents | 1996 |
Changes in the baroreflex control of heart rate produced by central infusion of selective angiotensin antagonists in hypertensive rats.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Baroreflex; Biphenyl Compounds; Heart Rate; Imidazoles; Losartan; Male; Oligopeptides; Peptide Fragments; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Tetrazoles | 1996 |
Angiotensin II receptors and angiotensin II stimulation of ciliary activity in human fallopian tube.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Biphenyl Compounds; Cilia; Fallopian Tubes; Female; Humans; Imidazoles; Immunoenzyme Techniques; Losartan; Oligopeptides; Pregnancy; Premenopause; Receptors, Angiotensin; Tetrazoles; Tissue Distribution | 1996 |
Differential inducibility of angiotensin II AT2 receptor between SHR and WKY vascular smooth muscle cells.
Topics: 1-Sarcosine-8-Isoleucine Angiotensin II; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Aorta, Thoracic; Blotting, Northern; Cells, Cultured; In Vitro Techniques; Insulin; Iodine Radioisotopes; Muscle, Smooth, Vascular; Oligopeptides; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Angiotensin; RNA | 1996 |
Angiotensin II type 2 receptor-mediated regulation of rat neuronal K+ channels.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Cells, Cultured; Imidazoles; Kinetics; Losartan; Neurons; Oligopeptides; Patch-Clamp Techniques; Potassium Channels; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin; Tetrazoles | 1996 |
The contribution of AT1 and AT2 angiotensin receptors to its cognitive effects.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Biphenyl Compounds; Cognition; Imidazoles; Losartan; Oligopeptides; Rats; Receptors, Angiotensin; Tetrazoles | 1996 |
Angiotensin II receptor expression in the conduction system and arterial duct of neonatal and adult rat hearts.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Animals, Newborn; Atrioventricular Node; Autoradiography; Binding Sites; Biphenyl Compounds; Female; Imidazoles; Iodine Radioisotopes; Losartan; Male; Oligopeptides; Pregnancy; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin; Tetrazoles | 1996 |
Increased non-angiotensin II [125I]CGP 42112 binding in rat carotid artery after balloon injury.
Topics: Angiotensin II; Animals; Autoradiography; Carotid Arteries; Carotid Artery Injuries; Catheterization; Immunohistochemistry; Inflammation; Iodine Radioisotopes; Macrophages; Male; Oligopeptides; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin | 1996 |
Potentiation of purinergic transmission by angiotensin in prostatic rat vas deferens.
Topics: Adrenergic Uptake Inhibitors; Angiotensin I; Angiotensin II; Animals; Biphenyl Compounds; Electric Stimulation; Imidazoles; In Vitro Techniques; Losartan; Male; Muscle Contraction; Norepinephrine; Oligopeptides; Prostate; Protease Inhibitors; Purinergic P2 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P2; Reserpine; Synaptic Transmission; Tetrazoles; Vas Deferens | 1996 |
Expression of non-angiotensin II -125I-CGP 42112 binding sites on activated microglia after kainic acid induced neurodegeneration.
Topics: Angiotensin II; Animals; Autoradiography; Binding Sites; Dose-Response Relationship, Drug; Hippocampus; Kainic Acid; Male; Microglia; Nerve Degeneration; Oligopeptides; Rats; Rats, Sprague-Dawley; Time Factors | 1995 |
The role of brain angiotensin in thirst and AVP release induced by hemorrhage.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Biphenyl Compounds; Blood Pressure; Blood Volume; Captopril; Cohort Studies; Colony-Stimulating Factors; Drinking; Hemorrhage; Hypothalamus; Imidazoles; Injections, Intraperitoneal; Injections, Intraventricular; Losartan; Male; Oligopeptides; Radioimmunoassay; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin; Recombinant Proteins; Tetrazoles; Thirst; Time Factors; Vasopressins | 1996 |
The angiotensin II type 2 receptor primarily inhibits cell growth via pertussis toxin-sensitive G proteins.
Topics: 3T3 Cells; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Binding, Competitive; Biphenyl Compounds; Cell Division; GTP-Binding Proteins; Imidazoles; Kinetics; Losartan; Mice; Oligopeptides; Pertussis Toxin; Rats; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Recombinant Proteins; Tetrazoles; Transfection; Virulence Factors, Bordetella | 1996 |
The presence of angiotensin II receptors in elasmobranchs.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Atrial Natriuretic Factor; Benzimidazoles; Binding, Competitive; Biphenyl Compounds; Bradykinin; Branchial Region; Dose-Response Relationship, Drug; Elasmobranchii; Iodine Radioisotopes; Membrane Proteins; Natriuretic Peptide, C-Type; Oligopeptides; Proteins; Radioligand Assay; Receptors, Angiotensin; Tetrazoles; Time Factors; Tissue Distribution | 1997 |
Regulation of angiotensin II receptor AT1 subtypes in renal afferent arterioles during chronic changes in sodium diet.
Topics: Actins; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Biphenyl Compounds; Cloning, Molecular; Culture Techniques; DNA, Complementary; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Enalaprilat; Gene Expression Regulation; Imidazoles; Kidney; Losartan; Male; Oligopeptides; Polymerase Chain Reaction; Pyridines; Rats; Rats, Wistar; Receptors, Angiotensin; Renal Artery; Renal Circulation; Ribonucleases; RNA, Messenger; Sodium, Dietary; Tetrazoles; Vasoconstrictor Agents | 1997 |
Mapping of angiotensin II receptor subtypes in peripheral tissues of spontaneously hypertensive rats by in vitro autoradiography.
Topics: Adrenal Glands; Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Autoradiography; Benzimidazoles; Biphenyl Compounds; Heart; Hypertension; Kidney; Male; Muscle, Smooth, Vascular; Myocardium; Oligopeptides; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Angiotensin; Tetrazoles | 1995 |
Cardiovascular effects produced by microinjection of angiotensins and angiotensin antagonists into the ventrolateral medulla of freely moving rats.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Blood Pressure; Heart Rate; Imidazoles; Losartan; Male; Medulla Oblongata; Microinjections; Oligopeptides; Peptide Fragments; Rats; Rats, Wistar; Tetrazoles; Time Factors | 1997 |
Cloning and expression of angiotensin II type 2 (AT2) receptors from murine neuroblastoma N1E-115 cells: evidence for AT2 receptor heterogeneity.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Cell Membrane; Cloning, Molecular; COS Cells; Dithiothreitol; DNA, Complementary; Imidazoles; Locus Coeruleus; Losartan; Mice; Neuroblastoma; Oligopeptides; Olivary Nucleus; Polymerase Chain Reaction; Pyridines; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Recombinant Proteins; Tetrazoles; Transfection; Tumor Cells, Cultured | 1997 |
Angiotensin II type 1 receptor expression in human breast tissues.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Antibodies, Monoclonal; Antihypertensive Agents; Binding Sites; Binding, Competitive; Biphenyl Compounds; Breast; Breast Neoplasms; Electrophoresis, Polyacrylamide Gel; Female; Humans; Imidazoles; Immunohistochemistry; Losartan; Oligopeptides; Receptors, Angiotensin; Tetrazoles | 1997 |
ANG II AT1 and AT2 receptors both inhibit bFGF-induced proliferation of bovine adrenocortical cells.
Topics: Adrenal Cortex; Angiotensin II; Animals; Cattle; Cell Cycle; Cell Division; Cells, Cultured; Cyclin D1; Dinoprostone; Fibroblast Growth Factor 2; G1 Phase; Imidazoles; Indomethacin; Oligopeptides; Prostaglandin D2; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin | 1997 |
Enhancement by exogenous and locally generated angiotensin II of purinergic neurotransmission via angiotensin type 1 receptor in the guinea-pig isolated mesenteric artery.
Topics: Adenosine Triphosphate; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Benzimidazoles; Biphenyl Compounds; Electric Stimulation; Evoked Potentials; Female; Guinea Pigs; Imidazoles; In Vitro Techniques; Membrane Potentials; Mesenteric Arteries; Muscle Contraction; Muscle, Smooth, Vascular; Oligopeptides; Purinergic P2 Receptor Antagonists; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Suramin; Synaptic Transmission; Tetrazoles; Vasoconstrictor Agents | 1997 |
CGP 42112A abolishes facilitation of recognition caused by angiotensin II and angiotensin II(3-7) in rats.
Topics: Angiotensin II; Animals; Behavior, Animal; Locomotion; Male; Memory; Oligopeptides; Pattern Recognition, Visual; Peptide Fragments; Rats; Rats, Wistar | 1997 |
Dose-dependent inhibitory effects of angiotensin II on visual responses of the rat superior colliculus: AT1 and AT2 receptor contributions.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Dose-Response Relationship, Drug; Evoked Potentials, Visual; Mesencephalon; Oligopeptides; Rats; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin | 1997 |
Role of Lys215 located in the fifth transmembrane domain of the AT2 receptor in ligand-receptor interaction.
Topics: 1-Sarcosine-8-Isoleucine Angiotensin II; Amino Acid Sequence; Angiotensin II; Angiotensin II Type 2 Receptor Blockers; Angiotensin Receptor Antagonists; Animals; Binding Sites; Imidazoles; Ligands; Lysine; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Oligopeptides; Protein Conformation; Pyridines; Rats; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Recombinant Proteins | 1998 |
Distribution and functional significance of angiotensin-II AT1- and AT2-receptor subtypes in the rat adrenal gland.
Topics: Adrenal Glands; Aldosterone; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Autoradiography; Catecholamines; Imidazoles; Iodine Radioisotopes; Losartan; Male; Oligopeptides; Osmolar Concentration; Pyridines; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin | 1998 |
Characterization and distribution of angiotensin II receptor subtypes in the mouse brain.
Topics: Angiotensin II; Animals; Autoradiography; Binding, Competitive; Brain Chemistry; Caudate Nucleus; Imidazoles; In Vitro Techniques; Kinetics; Ligands; Locus Coeruleus; Losartan; Male; Mice; Mice, Inbred C57BL; Oligopeptides; Pyridines; Rats; Receptors, Angiotensin | 1998 |
Regulation of jejunal sodium and water absorption by angiotensin subtype receptors.
Topics: Adrenergic alpha-1 Receptor Antagonists; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Cyclic AMP; Cyclic GMP; Diet, Sodium-Restricted; Dinoprostone; Dose-Response Relationship, Drug; Guanethidine; Homeostasis; Imidazoles; Intestinal Absorption; Intestinal Mucosa; Jejunum; Kinetics; Losartan; Male; Mesenteric Arteries; Oligopeptides; Prazosin; Pyridines; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Time Factors; Water | 1998 |
Angiotensin II and insulin induce growth of ciliary artery smooth muscle: effects of AT1/AT2 antagonists.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Cell Count; Cell Division; Cell Movement; Cells, Cultured; Ciliary Arteries; DNA; DNA Replication; Dose-Response Relationship, Drug; Drug Combinations; Insulin; Muscle, Smooth, Vascular; Oligopeptides; Swine; Tetrazoles; Valine; Valsartan | 1998 |
Angiotensin II receptors on colorectal carcinoma cells.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Cell Line, Tumor; Cell Membrane; Colorectal Neoplasms; Humans; Iodine Radioisotopes; Losartan; Oligopeptides; Receptor, Angiotensin, Type 2 | 1998 |
Modulation of AT1 receptor-mediated contraction of rat uterine artery by AT2 receptors.
Topics: Angiotensin II; Animals; Arteries; Female; Imidazoles; Losartan; Oligopeptides; Phenylephrine; Pregnancy; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Uterus; Vasoconstriction | 1998 |
Renal proximal tubular AT2 receptor: signaling and transport.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Arachidonic Acid; Biological Transport; Cells, Cultured; Dose-Response Relationship, Drug; GTP-Binding Proteins; Imidazoles; Kidney Tubules, Proximal; Mice; Oligopeptides; Phospholipases A; Phospholipases A2; Pyridines; Rabbits; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Signal Transduction; Sodium Bicarbonate | 1999 |
CGP 42112A antagonism of the angiotensin II and angiotensin II(3-7) facilitation of recall in rats.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Avoidance Learning; Behavior, Animal; Injections, Intraventricular; Male; Mental Recall; Oligopeptides; Peptide Fragments; Rats; Rats, Wistar; Receptors, Angiotensin | 1998 |
Role of the His273 located in the sixth transmembrane domain of the angiotensin II receptor subtype AT2 in ligand-receptor interaction.
Topics: Amino Acid Substitution; Angiotensin II; Animals; Binding Sites; Cell Membrane; Histidine; Ligands; Lysine; Oligopeptides; Oocytes; Rats; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; RNA, Messenger; Saralasin; Structure-Activity Relationship; Xenopus laevis | 1999 |
Effect of luminal angiotensin II receptor antagonists on proximal tubule transport.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Imidazoles; Ion Transport; Kidney Tubules, Proximal; Losartan; Male; Oligopeptides; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Sodium | 1999 |
Characterization of a functional AT1A angiotensin receptor in pancreatoma AR4-2J cells.
Topics: Amylases; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Base Sequence; Cell Line; DNA Primers; Inositol Phosphates; Kinetics; Losartan; Oligopeptides; Pancreas; Rats; Receptor, Angiotensin, Type 1; Receptors, Angiotensin; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 1999 |
Activation of the AT(2) receptor of angiotensin II induces neurite outgrowth and cell migration in microexplant cultures of the cerebellum.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Blotting, Western; Cell Differentiation; Cell Movement; Cerebellum; Culture Techniques; Fluorescent Antibody Technique, Indirect; Imidazoles; Losartan; Microtubule-Associated Proteins; Neurites; Oligopeptides; Pyridines; Rats; Rats, Long-Evans; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Signal Transduction; tau Proteins; Tubulin | 1999 |
Renal effects of angiotensin II receptor subtype 1 and 2-selective ligands injected into the paraventricular nucleus of conscious rats.
Topics: Angiotensin II; Animals; Injections, Intraventricular; Kidney; Ligands; Losartan; Male; Oligopeptides; Paraventricular Hypothalamic Nucleus; Potassium; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin; Saralasin; Sodium | 1999 |
Functional involvement of angiotensin AT2 receptor in adrenal catecholamine secretion in vivo.
Topics: Adrenal Glands; Angiotensin II; Animals; Calcium Channels, L-Type; Catecholamines; Dogs; Imidazoles; Male; Oligopeptides; Pyridines; Receptors, Angiotensin | 1999 |
Pharmacological characterization of KR-30988, a novel non-peptide AT1 receptor antagonist, in rat, rabbit and dog.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Aorta; Dogs; Furosemide; Hypertension, Renal; Imidazoles; Losartan; Male; Oligopeptides; Pressoreceptors; Rabbits; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Recombinant Proteins; Tetrazoles; Vasoconstriction | 1999 |
Renal vascular reactivity in mice: AngII-induced vasoconstriction in AT1A receptor null mice.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Female; Imidazoles; Losartan; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Oligopeptides; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Renal Circulation; Renin; Vasoconstriction | 1999 |
Involvement of the angiotensin II type 2 receptor in apoptosis during human fetal adrenal gland development.
Topics: Actin Cytoskeleton; Adrenal Glands; Angiotensin II; Angiotensin II Type 2 Receptor Blockers; Angiotensin Receptor Antagonists; Apoptosis; Blotting, Western; DNA Fragmentation; DNA Repair; Fluorescent Antibody Technique; Gestational Age; Humans; Oligopeptides; Receptor, Angiotensin, Type 2; Receptors, Angiotensin | 1999 |
Angiotensin AT1 receptors in the preoptic area negatively modulate the cardiovascular and ACTH responses induced in rats by intrapreoptic injection of prostaglandin E2.
Topics: Adrenocorticotropic Hormone; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Blood Pressure; Cardiovascular System; Dinoprostone; Injections; Losartan; Male; Oligopeptides; Preoptic Area; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin | 2000 |
Angiotensin-II subtype 2 receptor agonist (CGP-42112) inhibits catecholamine biosynthesis in cultured porcine adrenal medullary chromaffin cells.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adrenal Medulla; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Benzimidazoles; Binding, Competitive; Biphenyl Compounds; Catecholamines; Cells, Cultured; Chromaffin Cells; Cyclic GMP; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Induction; Imidazoles; Oligopeptides; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; RNA, Messenger; Swine; Tetrazoles; Tyrosine 3-Monooxygenase | 2000 |
Angiotensin type 2 receptor is expressed in the adult rat kidney and promotes cellular proliferation and apoptosis.
Topics: Age Factors; Angiotensin II; Animals; Antihypertensive Agents; Apoptosis; Autoradiography; Blood Pressure; Cell Division; Gene Expression; Guanosine 5'-O-(3-Thiotriphosphate); Imidazoles; In Situ Nick-End Labeling; Iodine Radioisotopes; Kidney; Male; Oligopeptides; Organ Size; Osteopontin; Proliferating Cell Nuclear Antigen; Pyridines; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; RNA, Messenger; Sialoglycoproteins; Tetrazoles; Valine; Valsartan | 2000 |
Angiotensin II binding sites in the heart of Scyliorhinus canicula: an autoradiographic study.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Autoradiography; Benzimidazoles; Binding Sites; Biphenyl Compounds; Dogfish; Endocardium; Heart Atria; Iodine Radioisotopes; Myocardium; Oligopeptides; Receptors, Angiotensin; Tetrazoles | 2001 |
Intracellular Angiotensin II and cell growth of vascular smooth muscle cells.
Topics: Androstadienes; Angiotensin II; Animals; Cell Count; Cell Division; Dose-Response Relationship, Drug; Imidazoles; Liposomes; Losartan; Muscle, Smooth, Vascular; Oligopeptides; Pyridines; Thymidine; Wortmannin | 2001 |
Angiotensin II type 2 receptor-mediated duodenal mucosal alkaline secretion in the rat.
Topics: Anesthetics, Local; Angiotensin II; Animals; Bicarbonates; Duodenum; Intestinal Mucosa; Lidocaine; Male; Oligopeptides; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Tissue Distribution | 2001 |
Vascular expression of angiotensin type 2 receptor in the adult rat: influence of angiotensin II infusion.
Topics: Angiotensin II; Animals; Autoradiography; Gene Expression; Immunohistochemistry; Infusions, Parenteral; Male; Mesenteric Arteries; Oligopeptides; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2001 |
Activation of angiotensin II subtype 2 receptor induces catecholamine release in an extracellular Ca(2+)-dependent manner through a decrease of cyclic guanosine 3',5'-monophosphate production in cultured porcine adrenal medullary chromaffin Cells.
Topics: Adrenal Medulla; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Benzimidazoles; Biphenyl Compounds; Calcium; Catecholamines; Cells, Cultured; Chromaffin Cells; Cyclic GMP; Extracellular Space; Imidazoles; Inositol 1,4,5-Trisphosphate; Intracellular Membranes; Oligopeptides; Pyridines; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Swine; Tetrazoles; Virulence Factors, Bordetella | 2001 |
Differential regulation of thrombospondin-1 and fibronectin by angiotensin II receptor subtypes in cultured endothelial cells.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Aorta; Arteriosclerosis; Blotting, Northern; Cattle; Cell Division; Cells, Cultured; DNA; Dose-Response Relationship, Drug; Endothelium, Vascular; Fibronectins; Imidazoles; Losartan; Male; Oligopeptides; Pyridines; Rats; Rats, Wistar; Receptors, Angiotensin; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Thrombospondin 1 | 2001 |
Angiotensin II type AT(2) receptor mRNA expression and renal vasodilatation are increased in renal failure.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; 5,8,11,14-Eicosatetraynoic Acid; Angiotensin II; Animals; Antihypertensive Agents; Arachidonic Acid; Clotrimazole; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Gene Expression Regulation; Imidazoles; In Vitro Techniques; Indomethacin; Kidney; Losartan; Male; NG-Nitroarginine Methyl Ester; Oligopeptides; Pyridines; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Renal Insufficiency; RNA, Messenger; Vasodilation | 2001 |
Angiotensin II enhances noradrenaline release from sympathetic nerves of the rat prostate via a novel angiotensin receptor: implications for the pathophysiology of benign prostatic hyperplasia.
Topics: Analysis of Variance; Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Bradykinin; Captopril; CHO Cells; Cricetinae; Dose-Response Relationship, Drug; Imidazoles; Losartan; Male; Norepinephrine; Oligopeptides; Prostate; Prostatic Hyperplasia; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin; Sympathetic Nervous System; Synaptic Transmission | 2001 |
Effects of angiotensin II microinjected into medial amygdala on male sexual behavior in rats.
Topics: Amygdala; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Losartan; Male; Microinjections; Oligopeptides; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Sexual Behavior, Animal; Vasoconstrictor Agents | 2002 |
Angiotensin II stimulation of Na+/K+ATPase activity and cell growth by calcium-independent pathway in MCF-7 breast cancer cells.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Breast Neoplasms; Cell Division; Dose-Response Relationship, Drug; Enzyme Inhibitors; Epithelial Cells; Female; Gene Expression; Humans; Losartan; Oligopeptides; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Reverse Transcriptase Polymerase Chain Reaction; Sodium-Potassium-Exchanging ATPase; Stimulation, Chemical; Tumor Cells, Cultured | 2002 |
No net effect of angiotensin II on blood pressure?
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Blood Pressure; Hypotension; Imidazoles; Oligopeptides; Pyridines; Receptor, Angiotensin, Type 2 | 2002 |
Angiotensin II type 1 and 2 receptors in conduit arteries of normal developing microswine.
Topics: Actins; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Angiotensin Receptor Antagonists; Animals; Animals, Newborn; Aorta, Abdominal; Aorta, Thoracic; Autoradiography; Binding Sites; Fetus; Iodine Radioisotopes; Membranes; Muscle, Smooth; Oligopeptides; Radioligand Assay; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Swine; Swine, Miniature; Tunica Media | 2002 |
AT2 receptor-mediated relaxation is preserved after long-term AT1 receptor blockade.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Benzimidazoles; Biphenyl Compounds; Culture Techniques; Dose-Response Relationship, Drug; Kinetics; Male; Mesenteric Arteries; Oligopeptides; Rats; Rats, Inbred WKY; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Reproducibility of Results; Tetrazoles; Vasoconstrictor Agents; Vasodilation | 2002 |
Binding of KRH-594, an antagonist of the angiotensin II type 1 receptor, to cloned human and rat angiotensin II receptors.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Benzimidazoles; Biphenyl Compounds; Chlorocebus aethiops; COS Cells; Dose-Response Relationship, Drug; Humans; Imidazoles; In Vitro Techniques; Liver; Losartan; Membranes; Oligopeptides; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Tetrazoles; Thiadiazoles; Time Factors; Transfection | 2002 |
Localization of AT(2) receptors in the nucleus of the solitary tract of spontaneously hypertensive and Wistar Kyoto rats using [125I] CGP42112: upregulation of a non-angiotensin II binding site following unilateral nodose ganglionectomy.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Autoradiography; Binding, Competitive; Brain; Dose-Response Relationship, Drug; Functional Laterality; Ganglionectomy; Imidazoles; Immunohistochemistry; Iodine Radioisotopes; Losartan; Male; Nodose Ganglion; Oligopeptides; Pyridines; Radioligand Assay; Radiopharmaceuticals; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Angiotensin; Solitary Nucleus | 2003 |
Angiotensin II and III microinjections into the zona incerta influence drinking behavior.
Topics: Angiotensin II; Angiotensin III; Animals; Antihypertensive Agents; Dose-Response Relationship, Drug; Drinking; Drinking Behavior; Drug Interactions; Imidazoles; Losartan; Male; Microinjections; Oligopeptides; Pyridines; Rats; Subthalamus; Time Factors | 2003 |
Angiotensin II type 2 receptor inhibits vascular endothelial growth factor-induced migration and in vitro tube formation of human endothelial cells.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Apoptosis; Blotting, Western; Cell Line; Cell Movement; Cells, Cultured; Dose-Response Relationship, Drug; Endothelial Growth Factors; Endothelium, Vascular; Humans; Imidazoles; Intercellular Signaling Peptides and Proteins; Losartan; Lymphokines; Neovascularization, Physiologic; Oligopeptides; Pertussis Toxin; Phosphorylation; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Signal Transduction; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor Receptor-2; Vascular Endothelial Growth Factors | 2003 |
Angiotensin II mediates Tyr-dephosphorylation in rat fetal kidney membranes.
Topics: Angiotensin II; Animals; Blotting, Western; Cell Membrane; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Enzyme Inhibitors; Female; Imidazoles; Immunoblotting; Kidney; Oligopeptides; Phosphorylation; Phosphotyrosine; Pyridines; Rats; Rats, Inbred WKY; Signal Transduction; Tyrosine; Vanadates | 2003 |
Regulation of inhibitory protein-kappaB and monocyte chemoattractant protein-1 by angiotensin II type 2 receptor-activated Src homology protein tyrosine phosphatase-1 in fetal vascular smooth muscle cells.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Animals; Cells, Cultured; Chemokine CCL2; Cytosol; Gene Expression Regulation; I-kappa B Proteins; Imidazoles; Intracellular Signaling Peptides and Proteins; Muscle, Smooth, Vascular; Mutation; NF-kappa B; Oligopeptides; Protein Phosphatase 1; Protein Tyrosine Phosphatase, Non-Receptor Type 1; Protein Tyrosine Phosphatase, Non-Receptor Type 6; Protein Tyrosine Phosphatases; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2 | 2004 |
Non-angiotensin II [(125)I] CGP42112 binding is a sensitive marker of neuronal injury in brainstem following unilateral nodose ganglionectomy: comparison with markers for activated microglia.
Topics: Angiotensin II; Animals; Autoradiography; Biomarkers; Brain Stem; Ganglionectomy; Glial Fibrillary Acidic Protein; Gliosis; Iodine Radioisotopes; Isoquinolines; Male; Microglia; Nodose Ganglion; Oligopeptides; Rats; Rats, Inbred WKY; Tritium; Vasoconstrictor Agents | 2004 |
Renal angiotensin II type-2 receptors are upregulated and mediate the candesartan-induced natriuresis/diuresis in obese Zucker rats.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Biphenyl Compounds; Diuresis; Imidazoles; Kidney; Male; Natriuresis; Obesity; Oligopeptides; Pyridines; Rats; Rats, Zucker; Receptor, Angiotensin, Type 2; Tetrazoles; Up-Regulation | 2005 |
A new role for the renin-angiotensin system in the rat periaqueductal gray matter: angiotensin receptor-mediated modulation of nociception.
Topics: Anesthetics, Local; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Dose-Response Relationship, Drug; Immunohistochemistry; Lidocaine; Losartan; Male; Nociceptors; Oligopeptides; Pain Measurement; Periaqueductal Gray; Rats; Rats, Wistar; Reaction Time; Receptors, Angiotensin; Renin-Angiotensin System; Time Factors | 2005 |
Angiotensin II increases human monocyte matrix metalloproteinase-1 through the AT2 receptor and prostaglandin E2: implications for atherosclerotic plaque rupture.
Topics: Angiotensin II; Angiotensin II Type 2 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Anti-Inflammatory Agents; Cells, Cultured; Coronary Artery Disease; Dinoprostone; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Hypertension; Imidazoles; Matrix Metalloproteinase 1; Monocytes; Myocardial Infarction; Oligopeptides; Phosphoprotein Phosphatases; Pyridines; Receptor, Angiotensin, Type 2; Time Factors; Tumor Necrosis Factor-alpha; Up-Regulation | 2005 |
The endothelium-dependent vasodilator effect of the nonpeptide Ang(1-7) mimic AVE 0991 is abolished in the aorta of mas-knockout mice.
Topics: Angiotensin I; Angiotensin II; Animals; Aorta, Thoracic; Endothelium, Vascular; Enzyme Inhibitors; Imidazoles; In Vitro Techniques; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type III; Oligopeptides; Peptide Fragments; Proto-Oncogene Mas; Proto-Oncogene Proteins; Receptors, G-Protein-Coupled; Vasoconstrictor Agents; Vasodilator Agents | 2005 |
Interaction between arginine vasopressin and angiotensin II receptors in the central regulation of sodium balance.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin Receptor Antagonists; Animals; Arginine Vasopressin; Blood Pressure; Dose-Response Relationship, Drug; Hypothalamus; Injections, Intraventricular; Losartan; Male; Oligopeptides; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin; Receptors, Vasopressin; Sodium | 2005 |
Nitric oxide contributes to AT2 but not AT1 angiotensin II receptor-mediated vasodilatation of porcine pial arteries and arterioles.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Animals; Arteries; Biphenyl Compounds; Enzyme Inhibitors; Female; Imidazoles; Male; Naphthyridines; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Oligopeptides; Pia Mater; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Swine; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents | 2005 |
Dynamic expression of the angiotensin II type 2 receptor and duodenal mucosal alkaline secretion in the Sprague-Dawley rat.
Topics: Angiotensin II; Animals; Dinoprostone; Duodenum; Intestinal Mucosa; Male; Oligopeptides; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; RNA, Messenger | 2006 |
Membrane currents elicited by angiotensin II in astrocytes from the rat corpus callosum.
Topics: Angiotensin II; Animals; Animals, Newborn; Astrocytes; Corpus Callosum; Electrophysiology; Glial Fibrillary Acidic Protein; Immunohistochemistry; Membrane Potentials; Naphthyridines; Oligopeptides; Patch-Clamp Techniques; Rats; Rats, Wistar | 2006 |
Opposing actions of angiotensin II type 1 and 2 receptors on plasma cholesterol levels in rats.
Topics: Angiotensin II; Angiotensin II Type 2 Receptor Blockers; Animals; Blood Pressure; Cholesterol; Imidazoles; Lipid Metabolism; Liver; Male; Oligopeptides; Olmesartan Medoxomil; Pyridines; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Tetrazoles | 2006 |
Angiotensin II AT2 receptors inhibit proximal tubular Na+-K+-ATPase activity via a NO/cGMP-dependent pathway.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Animals; Cyclic GMP; Diuresis; Enzyme Inhibitors; Glomerular Filtration Rate; Kidney Tubules, Proximal; Male; Natriuresis; Nitrates; Nitric Oxide; Nitrites; Oligopeptides; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Sodium-Potassium-Exchanging ATPase | 2006 |
Angiotensin II infusion decreases plasma adiponectin level via its type 1 receptor in rats: an implication for hypertension-related insulin resistance.
Topics: Adiponectin; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Animals; Blood Glucose; Dose-Response Relationship, Drug; Glucose Tolerance Test; Hypertension; Imidazoles; Injections, Subcutaneous; Insulin; Insulin Resistance; Leptin; Male; Oligopeptides; Pyridines; Rats; Rats, Wistar; Receptors, Adiponectin; Receptors, Cell Surface; Tetrazoles; Tumor Necrosis Factor-alpha | 2006 |
Angiotensin II-induced neural differentiation via angiotensin II type 2 (AT2) receptor-MMS2 cascade involving interaction between AT2 receptor-interacting protein and Src homology 2 domain-containing protein-tyrosine phosphatase 1.
Topics: Angiotensin II; Angiotensin II Type 2 Receptor Blockers; Animals; Carrier Proteins; Cell Differentiation; Cell Nucleus; Cells, Cultured; DNA Repair; Imidazoles; Inhibitor of Differentiation Protein 1; Ligases; Mice; Nerve Tissue Proteins; Neurites; Neurons; Oligopeptides; Protein Phosphatase 1; Protein Transport; Protein Tyrosine Phosphatase, Non-Receptor Type 6; Pyridines; Rats; Rats, Wistar; Receptor, Angiotensin, Type 2; Signal Transduction; Synapses; Tetrazoles; Transcriptional Activation; Tumor Suppressor Proteins; Valine; Valsartan; Vanadates | 2007 |
Angiotensin II type 2 receptor provides an endogenous brake during inflammation-induced microvascular fluid leak.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Capillary Permeability; Endothelium, Vascular; Female; Inflammation; Mesenteric Veins; Microcirculation; Models, Animal; Oligopeptides; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 2; Vascular Diseases | 2007 |
Angiotensin II type 2 receptor vasoactivity in internal mammary arteries of patients with coronary artery disease.
Topics: Acetylcholine; Adrenergic alpha-Antagonists; Adult; Aged; Aged, 80 and over; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Benzimidazoles; Biphenyl Compounds; Coronary Artery Disease; Female; Gene Expression; Humans; Imidazoles; In Vitro Techniques; Male; Mammary Arteries; Middle Aged; Oligopeptides; Phentolamine; Phenylephrine; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Sodium Nitrite; Tetrazoles; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents | 2007 |
Angiotensin (1-7) reduces intraocular pressure in the normotensive rabbit eye.
Topics: Administration, Topical; Angiotensin I; Angiotensin II; Angiotensin II Type 2 Receptor Blockers; Animals; Aqueous Humor; Dose-Response Relationship, Drug; Imidazoles; Injections; Intraocular Pressure; Male; Oligopeptides; Peptide Fragments; Pyridines; Rabbits; Receptor, Angiotensin, Type 2; Tonometry, Ocular; Vitreous Body | 2008 |
Angiotensin II type 2 receptor-mediated inhibition of norepinephrine release in isolated rat hearts.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Animals; Bradykinin; Heart; Imidazoles; In Vitro Techniques; Losartan; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Norepinephrine; Oligopeptides; Phenylalanine; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Sympathetic Nervous System; Tranexamic Acid; Vasoconstrictor Agents | 2008 |
Angiotensin II upregulates acyl-CoA:cholesterol acyltransferase-1 via the angiotensin II Type 1 receptor in human monocyte-macrophages.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Atherosclerosis; Benzimidazoles; Biphenyl Compounds; Cell Differentiation; Cells, Cultured; Dose-Response Relationship, Drug; Endocytosis; Foam Cells; Humans; Imidazoles; Macrophages; Male; Oligopeptides; Radioimmunoassay; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; RNA, Messenger; Signal Transduction; Sterol O-Acyltransferase; Tetrazoles; Up-Regulation; Vasoconstrictor Agents; Vasodilator Agents | 2008 |
Increased vascular angiotensin type 2 receptor expression and NOS-mediated mechanisms of vascular relaxation in pregnant rats.
Topics: Acetylcholine; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Aorta; Blood Pressure; Dose-Response Relationship, Drug; Endothelium, Vascular; Female; Imidazoles; Losartan; Muscle, Smooth, Vascular; Nitric Oxide; Nitric Oxide Synthase Type III; Oligopeptides; Phenylephrine; Phosphorylation; Pregnancy; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; RNA, Messenger; Up-Regulation; Vasoconstriction; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents | 2009 |
Ang-(3-4) suppresses inhibition of renal plasma membrane calcium pump by Ang II.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Calcium-Transporting ATPases; Cell Membrane; Chromatography, High Pressure Liquid; Enzyme Activation; Imidazoles; In Vitro Techniques; Kidney; Oligopeptides; Peptide Fragments; Pyridines; Receptors, Angiotensin; Sheep; Spectrometry, Mass, Electrospray Ionization; Vasoconstrictor Agents | 2009 |
Angiotensin III modulates the nociceptive control mediated by the periaqueductal gray matter.
Topics: Analgesics; Angiotensin II; Angiotensin III; Angiotensin Receptor Antagonists; Animals; Disease Models, Animal; Drug Interactions; Efferent Pathways; Glutamyl Aminopeptidase; Losartan; Male; Microinjections; Neural Inhibition; Nociceptors; Oligopeptides; Pain; Pain Measurement; Pain Threshold; Peptides; Periaqueductal Gray; Rats; Rats, Wistar; Receptors, Angiotensin | 2009 |
Angiotensin II AT2 receptor regulates ureteric bud morphogenesis.
Topics: Adaptor Proteins, Signal Transducing; Angiotensin II; Animals; Apoptosis; Cell Proliferation; Cell Survival; Cells, Cultured; Gene Expression Regulation, Developmental; Gestational Age; Glial Cell Line-Derived Neurotrophic Factor; Imidazoles; Immunohistochemistry; In Situ Hybridization; Membrane Proteins; Mice; Mice, Inbred C57BL; Mice, Knockout; Morphogenesis; Mutation; Oligopeptides; Organ Culture Techniques; Phosphoproteins; Proto-Oncogene Proteins c-ret; Pyridines; Receptor, Angiotensin, Type 2; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Ureter; Wnt Proteins | 2010 |
Angiotensin II type 2 receptor-dependent increase in nitric oxide synthase activity in the endothelium of db/db mice is mediated via a MEK pathway.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Aorta; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Disease Models, Animal; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Activation; Flavonoids; Losartan; Male; MAP Kinase Kinase 1; MAP Kinase Kinase 2; MAP Kinase Kinase Kinases; Mice; Mice, Inbred C57BL; Nitric Oxide; Nitric Oxide Synthase Type III; Oligopeptides; Phosphorylation; Protein Kinase Inhibitors; Receptor, Angiotensin, Type 2; Signal Transduction; Time Factors; Vasodilation; Vasodilator Agents | 2012 |
Angiotensin-(3-4) counteracts the Angiotensin II inhibitory action on renal Ca2+-ATPase through a cAMP/PKA pathway.
Topics: Allosteric Regulation; Angiotensin II; Angiotensin II Type 2 Receptor Blockers; Animals; Binding, Competitive; Calcium-Transporting ATPases; Cell Membrane; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Enzyme Assays; HEK293 Cells; Humans; Imidazoles; Immunoprecipitation; Kidney Tubules, Proximal; Losartan; Oligopeptides; Phosphorylation; Protein Binding; Protein Conformation; Pyridines; Receptor, Angiotensin, Type 2; Sheep; Signal Transduction; Transfection | 2012 |
Role of angiotensin AT2 receptors and nitric oxide in the cardiopulmonary baroreflex control of renal sympathetic nerve activity in rats.
Topics: Angiotensin II; Angiotensin II Type 2 Receptor Blockers; Animals; Baroreflex; Blood Pressure; Enzyme Inhibitors; Imidazoles; Kidney; Losartan; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Oligopeptides; Pyridines; Rats; Rats, Wistar; Receptor, Angiotensin, Type 2; Sympathetic Nervous System | 2013 |
Angiotensin AT2 receptor agonist stimulates high stretch induced- ANP secretion via PI3K/NO/sGC/PKG/pathway.
Topics: Angiotensin II; Animals; Atrial Natriuretic Factor; Atrial Pressure; Cyclic GMP-Dependent Protein Kinases; Gene Expression Regulation; Guanylate Cyclase; Heart Atria; Hypertension, Renal; Imidazoles; Losartan; Male; Nitric Oxide; Oligopeptides; Peptide Fragments; Phosphatidylinositol 3-Kinases; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 2; Receptors, Cytoplasmic and Nuclear; Signal Transduction; Soluble Guanylyl Cyclase; Tissue Culture Techniques; Vasodilator Agents | 2013 |
Humoral control of cardiac remodeling in fish: role of Angiotensin II.
Topics: Angiotensin II; Animals; Apoptosis; Eels; Heart; Nitric Oxide Synthase Type III; Oligopeptides; Receptor, Angiotensin, Type 2 | 2013 |
Angiotensin II type 2 receptor correlates with therapeutic effects of losartan in rats with adjuvant-induced arthritis.
Topics: Angiotensin II; Animals; Ankle Joint; Arthritis, Experimental; Cells, Cultured; Chemotaxis; Injections, Intra-Articular; Losartan; Male; Monocytes; Oligopeptides; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Tumor Necrosis Factor-alpha; Up-Regulation; Vascular Endothelial Growth Factor A | 2013 |
Preconditioning via angiotensin type 2 receptor activation improves therapeutic efficacy of bone marrow mononuclear cells for cardiac repair.
Topics: Angiotensin II; Animals; Apoptosis; Bone Marrow Cells; Cell Transplantation; Coculture Techniques; Echocardiography; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Inflammation; Leukocytes, Mononuclear; Male; Myocardial Infarction; Myocytes, Cardiac; Neovascularization, Physiologic; Nitric Oxide; Nitric Oxide Synthase Type III; Oligopeptides; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Stem Cell Transplantation; Tetrazoles; Valine; Valsartan; Vascular Endothelial Growth Factor A | 2013 |
The role of brain angiotensin II (type 2) receptors and nitric oxide in the renal sympathoinhibitory response to acute volume expansion in conscious rats.
Topics: Administration, Intravenous; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Animals; Arterial Pressure; Body Fluids; Brain; Enzyme Inhibitors; Heart Rate; Imidazoles; Infusions, Intraventricular; Kidney; Losartan; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Oligopeptides; Pyridines; Rats; Receptor, Angiotensin, Type 2; Sodium Chloride; Sympathetic Nervous System | 2017 |
AT1 and AT2 receptors modulate renal tubular cell necroptosis in angiotensin II-infused renal injury mice.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Animals; Cell Line; Disease Models, Animal; Epithelial Cells; Humans; Imidazoles; Kidney Failure, Chronic; Kidney Tubules; Losartan; Male; Mice; Necroptosis; Oligopeptides; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Signal Transduction | 2019 |