Page last updated: 2024-09-03

cgp 36742 and (1,2,5,6-tetrahydropyridin-4-yl)methylphosphinic acid

cgp 36742 has been researched along with (1,2,5,6-tetrahydropyridin-4-yl)methylphosphinic acid in 3 studies

Compound Research Comparison

Studies
(cgp 36742)
Trials
(cgp 36742)
Recent Studies (post-2010)
(cgp 36742)
Studies
((1,2,5,6-tetrahydropyridin-4-yl)methylphosphinic acid)
Trials
((1,2,5,6-tetrahydropyridin-4-yl)methylphosphinic acid)
Recent Studies (post-2010) ((1,2,5,6-tetrahydropyridin-4-yl)methylphosphinic acid)
633281027

Protein Interaction Comparison

ProteinTaxonomycgp 36742 (IC50)(1,2,5,6-tetrahydropyridin-4-yl)methylphosphinic acid (IC50)
Gamma-aminobutyric acid receptor subunit rho-1Homo sapiens (human)2.22

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (66.67)29.6817
2010's1 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chebib, M; Hanrahan, JR; Hibbs, DE; Johnston, GA; Kim, HL; Kumar, RJ; Salam, NK1
Ai, TH; Burden, PM; Chebib, M; Gavande, N; Hanrahan, JR; Johnston, GA; Salam, NK; Yamamoto, I1
Johnston, GA1

Reviews

1 review(s) available for cgp 36742 and (1,2,5,6-tetrahydropyridin-4-yl)methylphosphinic acid

ArticleYear
Medicinal chemistry and molecular pharmacology of GABA(C) receptors.
    Current topics in medicinal chemistry, 2002, Volume: 2, Issue:8

    Topics: Amino Acids, Cyclic; Animals; Barbiturates; Crotonates; GABA Agonists; GABA Antagonists; Imidazoles; Isoxazoles; Muscimol; Organophosphorus Compounds; Phosphinic Acids; Pyridines; Receptors, GABA; Receptors, GABA-A

2002

Other Studies

2 other study(ies) available for cgp 36742 and (1,2,5,6-tetrahydropyridin-4-yl)methylphosphinic acid

ArticleYear
Novel gamma-aminobutyric acid rho1 receptor antagonists; synthesis, pharmacological activity and structure-activity relationships.
    Journal of medicinal chemistry, 2008, Jul-10, Volume: 51, Issue:13

    Topics: Animals; Female; GABA Antagonists; Ligands; Models, Molecular; Molecular Structure; Oocytes; Structure-Activity Relationship; Xenopus laevis

2008
Novel Cyclic Phosphinic Acids as GABAC ρ Receptor Antagonists: Design, Synthesis, and Pharmacology.
    ACS medicinal chemistry letters, 2011, Jan-13, Volume: 2, Issue:1

    Topics:

2011