cgp 35348 has been researched along with baclofen in 194 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 136 (70.10) | 18.2507 |
| 2000's | 47 (24.23) | 29.6817 |
| 2010's | 10 (5.15) | 24.3611 |
| 2020's | 1 (0.52) | 2.80 |
| Authors | Studies |
|---|---|
| Hausdorf, A; Karlsson, G; Kolb, C; Olpe, HR; Portet, C; Schmutz, M | 1 |
| Depaulis, A; Liu, Z; Marescaux, C; Vergnes, M | 1 |
| Snead, OC | 2 |
| Cao, Z; Clark, S; Hosford, DA; Huin, A; Lin, FH; Morrisett, RA; Wilson, WA | 1 |
| Douglas, WW; Kongsamut, S; Shibuya, I | 2 |
| Bernasconi, R; Bittiger, H; Lauber, J; Leonhardt, T; Marescaux, C; Martin, P; Reymann, N; Rubio, V; Vergnes, M | 1 |
| Bernasconi, R; Marescaux, C; Vergnes, M | 1 |
| Hafner, T; Karlsson, G; Klebs, K; Olpe, HR; Schmutz, M | 1 |
| Nicoll, RA; Solís, JM | 1 |
| Fromm, GH; Nakata, M; Sato, K | 1 |
| Bartolini, A; Ghelardini, C; Giotti, A; Malcangio, M; Malmberg-Aiello, P | 2 |
| Brooker, G; Costa, E; De Erausquin, G; Wojcik, WJ | 1 |
| Holopainen, I; Rau, C; Wojcik, WJ | 1 |
| Kaneto, H; Takahashi, M; Tokuyama, S | 1 |
| Bernasconi, R; Depaulis, A; Liu, Z; Marescaux, C; Vergnes, M | 1 |
| Avoli, M; Siniscalchi, A | 1 |
| Mody, I; Otis, TS | 1 |
| Bonanno, G; Raiteri, M | 2 |
| Bonanno, G; Gemignani, A; Lanza, M; Pende, M; Raiteri, M; Vellebuona, F | 1 |
| Feldtrauer, JJ; Stöcklin, K; Waldmeier, PC | 1 |
| Hills, JM; Howson, W; Larkin, MM | 1 |
| Waldmeier, PC | 1 |
| Jackson, HC; Nutt, DJ | 1 |
| Aley, KO; Kulkarni, SK | 1 |
| Malinowska, B; Molderings, G; Schlicker, E; Schneider, D | 1 |
| Collingridge, GL; Davies, CH; Pozza, MF; Starkey, SJ | 1 |
| Howson, W; Lacey, MG; Seabrook, GR | 1 |
| Karlsson, G; Olpe, HR | 1 |
| Bittiger, H; Brugger, F; Fagg, G; Froestl, W; Hall, RG; Karlsson, G; Olpe, HR; Pozza, MF; Steinmann, M; Van Riezen, H | 1 |
| Cao, Z; Hosford, DA; Kraemer, DL; Lin, FH; Wang, Y; Wilson, JT | 1 |
| Brucato, FH; Lewis, DV; Mott, DD; Swartzwelder, HS | 1 |
| Moshé, SL; Ortíz, J; Ptachewich, Y; Shinnar, S; Velísek, L; Velísková, J | 1 |
| Bowery, NG; Lemos, T; Richards, DA; Whitton, PS | 1 |
| Dirig, DM; Yaksh, TL | 1 |
| Trippenbach, T | 1 |
| Humeniuk, RE; Kerr, DI; Ong, J; White, JM | 1 |
| Faucher, LD; Grunder, SD; Pearce, RA | 1 |
| Kubin, L; Okabe, S; Woch, G | 1 |
| Agmo, A; Paredes, RG | 1 |
| Little, HJ; Mead, AJ | 1 |
| Bolser, DC; Chapman, RW; Hey, JA; Kreutner, W; Krobatsch, D; Mingo, G | 1 |
| Banerjee, PK; Snead, OC | 1 |
| Slaughter, MM; Tian, N | 1 |
| Bonanno, G; Cavazzani, P; Fassio, A; Raiteri, M | 1 |
| Bijak, M; Jarolimek, W; Misgeld, U | 1 |
| Humeniuk, RE; Ong, J; White, JM | 1 |
| Cabib, S; Castellano, C; Cestari, V; Puglisi-Allegra, S | 1 |
| Lake, N; Trippenbach, T | 1 |
| Bolser, DC; Chapman, RW; DeGennaro, FC; Egan, RW; Hey, JA; Kreutner, W; O'Reilly, S | 1 |
| Baumann, PA; Bittiger, H; Feldtrauer, JJ; Mickel, SJ; Waldmeier, PC; Wicki, P | 1 |
| Gruner, W; Silva, LR | 1 |
| Bonanno, G; Gemignani, A; Paudice, P; Raiteri, M | 1 |
| Finch, DM; Gigg, J; Tan, AM | 1 |
| Eriksson, B; Larsby, B; Niklasson, M; Tham, R | 1 |
| Goudreau, JL; Lookingland, KJ; Moore, KE; Wagner, EJ | 1 |
| Morishita, W; Sastry, BR | 2 |
| Curtis, DR; Lacey, G | 1 |
| Crunelli, V; Emri, Z; Juhász, G; Kékesi, KA; Salfay, O | 1 |
| Bonanno, G; Lanza, M; Pende, M; Raiteri, M | 1 |
| Lambert, NA; Wilson, WA | 1 |
| Lewis, DV; Mott, DD; Swartzwelder, HS; Wilson, WA; Xie, CW | 1 |
| Hammond, DL; McGowan, MK | 1 |
| Engberg, G; Nissbrandt, H | 2 |
| Baumann, PA; Christen, T; Waldmeier, PC | 1 |
| Blake, JF; Brugger, F; Cao, CQ; Collingridge, GL; Evans, RH; Headley, PM | 1 |
| DiScenna, PG; Nowicky, AV; Teyler, TJ | 1 |
| Avanzino, GL; Blanchi, D; Cogo, CE; Ermirio, R; Ruggeri, P; Weaver, LC | 1 |
| Aziz, SM; Bolser, DC; Chapman, RW; DeGennaro, FC; Egan, RW; Kreutner, W; Siegel, MI | 1 |
| Bowery, NG; Malcangio, M | 1 |
| Smart, TG; Xie, X | 1 |
| Berthelot, P; Curtis, DR; Debaert, M; Flouquet, N; Lacey, G; Vaccher, C; Vaccher, MP | 1 |
| Häusler, A; Monnet, G; Peter, O | 1 |
| Engberg, G; Kling-Petersen, T; Nissbrandt, H | 1 |
| Douglas, WW; Shibuya, I | 1 |
| Denavit-Saubié, M; Foutz, AS; Pierrefiche, O | 1 |
| Hammond, DL; Washington, JD | 1 |
| Chugh, Y; Saha, N; Sankaranaryanan, A; Sharma, PL | 1 |
| Abbenante, J; Doolette, DJ; Kerr, DI; Ong, J; Prager, RH | 1 |
| Kathmann, M; Malinowska, B; Schlicker, E | 1 |
| Kulkarni, SK; Sharma, AC | 1 |
| Sved, AF; Yin, M | 1 |
| Seifert, E; Trippenbach, T | 2 |
| Moshé, SL; Velísek, L; Velísková, J | 1 |
| Graham, BA; Hammond, DL; McGowan, MK; Navarrete, IM; Thomas, DA | 1 |
| Blandizzi, C; Carignani, D; Colucci, R; Crema, F; Del Tacca, M; Lazzeri, G; Natale, G | 1 |
| Bon, C; Galvan, M | 1 |
| Huguenard, JR; Ulrich, D | 1 |
| Feltz, P; Hayar, A; Piguet, P | 1 |
| Brailowsky, S; Di Scala, G; Meneses, S; Montiel, T | 1 |
| Clarac, F; Vinay, L | 1 |
| Antal, K; Crunelli, V; Emri, Z | 1 |
| Chowdhury, SA; Kawashima, T; Konishi, T; Matsunami, K | 1 |
| Crunelli, V; Dobolyi, A; Emri, Z; Juhász, G; Kékesi, KA; Nyitrai, G | 1 |
| Bowery, NG; Connelly, ST; daSilva, HM; Grobaski, KC; Ping, H; Shepard, PD | 1 |
| Lingenhöhl, K; Pozza, MF; Vaughn, MD | 1 |
| Crunelli, V; Emri, Z; Turner, JP | 1 |
| Ebenezer, IS; Houston, AJ; Wong, JC | 2 |
| Alger, BE; Lenz, RA; Pitler, TA | 1 |
| Amitai, Y; Connors, BW; Gil, Z | 1 |
| McCormick, DA; Sanchez-Vives, MV | 1 |
| Bal, T; McCormick, DA; Sanchez-Vives, MV | 1 |
| Binns, KE; Salt, TE | 1 |
| Johnson, SW; Shen, KZ | 1 |
| Collins, WF; Mendell, LM; Peshori, KR | 1 |
| Perkel, DJ; Schmidt, MF | 1 |
| Ben-Ari, Y; Caillard, O; Gaïarsa, JL; McLean, HA | 1 |
| Obrietan, K; van den Pol, AN | 1 |
| Kombian, SB; Mouginot, D; Pittman, QJ | 1 |
| Aroniadou-Anderjaska, V; Ennis, M; Keller, A; Sheppard, NF; Shipley, MT; Yagodin, S; Zimmer, LA | 1 |
| Akihara, M; Izumi, F; Kaibara, M; Kawano, C; Shibuya, I; Taniyama, K; Toyohira, Y; Ueda, Y; Uezono, Y; Yamashita, H; Yanagihara, N | 1 |
| Harayama, N; Kabashima, N; Shibuya, I; Tanaka, K; Ueta, Y; Yamashita, H | 1 |
| Dun, NJ; Lin, HH | 1 |
| Puil, E; Schwarz, DW; Tennigkeit, F | 1 |
| Agabio, R; Colombo, G; Gessa, GL; Lobina, C; Reali, R | 2 |
| Cheng, GJ; Hu, BR; Yu, ZF | 1 |
| Bonanno, G; Fassio, A; Raiteri, M; Sala, R; Schmid, G | 1 |
| Bosch, MA; Kelly, MJ; Rønnekleiv, K; Wagner, EJ | 1 |
| Bertrand, S; Cazalets, JR | 1 |
| Lorenzo, N; Stringer, JL | 1 |
| Olianas, MC; Onali, P | 1 |
| Bartolini, A; Ipponi, A; Lamberti, C; Malmberg-Aiello, P; Medica, A | 1 |
| Khansefid, N; Sabetkasai, M; Yahyavi, SH; Zarrindast, MR | 1 |
| Mousa-Ahmadi, E; Zarrindast, MR | 1 |
| Bosch, MA; Kelly, MJ; Rønnekleiv, OK; Wagner, EJ | 1 |
| Bussières, N; El Manira, A | 1 |
| Bowery, N; Castro, AR; Castro-Lopes, JM | 1 |
| Jovanović, K; Petrov, T; Stein, RB | 1 |
| Ahang, S; Sabetkasai, M; Shafaghi, B; Zarrindast, MR | 1 |
| Breese, GR; Criswell, HE; Yang, X | 1 |
| Alvarez, FJ; Lim, R; Walmsley, B | 1 |
| Bacciottini, L; Blandina, P; Colivicchi, MA; Giorgetti, M; Giovannini, MG; Goldfarb, J | 1 |
| Aroniadou-Anderjaska, V; Ennis, M; Priest, CA; Shipley, MT; Zhou, FM | 1 |
| Sahebgharani, M; Valizadeh, S; Zarrindast, M | 1 |
| Alger, BE; Martin, LA; Wei, DS | 1 |
| Mahmoudi, M; Zarrindast, MR | 2 |
| Hattori, T; Hida, W; Kikuchi, Y; Kurosawa, H; Ogawa, H; Okabe, S; Shirato, K; Tabata, M; Tun, Y | 1 |
| Chergui, K; Engberg, G; Erhardt, S; Mathé, JM; Svensson, TH | 1 |
| Chowdhury, SA; Matsunami, KI | 1 |
| Bakhsha, A; Rostami, P; Shafaghi, B; Zarrindast, MR | 1 |
| Cella, SG; Muller, EE; Pitsikas, N; Rigamonti, AE | 1 |
| Fang, Y; Kelly, MJ; Rønnekleiv, OK; Slugg, RM; Zheng, SX | 1 |
| Takemoto, Y | 1 |
| Chapman, V; Sokal, DM | 1 |
| Avoli, M; Benini, R; de Guzman, P; Omar, A | 1 |
| Isogai, O; Ito, S; Masubuchi, Y; Saito, S; Tsukamoto, K; Uchiyama, T; Yajima, Y | 1 |
| Ebenezer, IS; Patel, SM | 1 |
| Harte, M; O'Connor, WT | 1 |
| Carter, LP; Chen, W; Coop, A; France, CP; Koek, W; Lamb, RJ; Wu, H | 1 |
| Funahashi, H; Muroya, S; Shioda, S; Uramura, K; Yada, T | 1 |
| Imai, S; Khotib, J; Nakamura, A; Narita, M; Nurrochmad, A; Ozaki, M; Shibasaki, M; Suzuki, T; Yajima, Y | 1 |
| Chen, K; Li, HZ; Wang, JJ; Ye, N; Zhang, J | 1 |
| Amiri, YA; Ghoshooni, H; Haeri-Rohani, A; Pourmotabbed, A; Sahraei, H; Salimi, SH; Sepehri, H; Zahirodin, A; Zardooz, H | 1 |
| Johnson, SW; Munhall, AC | 1 |
| Delorey, TM; Handforth, A; Homanics, GE; Olsen, RW | 1 |
| Carter, LP; Coop, A; France, CP; Koek, W; Wu, H | 1 |
| Carter, LP; Chen, W; Coop, A; France, CP; Koek, W | 1 |
| Ghadimi, M; Ramezani-Tehrani, B; Sahebgharani, M; Zarrindast, MR | 1 |
| Castro-Lopes, JM; Neto, FL; Potes, CS | 1 |
| Badiu, CI; Bessaïh, T; Bourgeais, L; Carter, DA; Crunelli, V; Lambolez, B; Leresche, N; Ruano, D; Toth, TI | 1 |
| Coop, A; Koek, W; Mercer, SL | 1 |
| Balcar, VJ; Griffin, JL; Nasrallah, FA; Rae, C | 1 |
| Sallagundala, N; Tzschentke, B; Yakimova, K | 1 |
| Baker, LE; Poling, A; Pynnonen, DM; Searcy, GD | 1 |
| Bongianni, F; Cinelli, E; Fontana, GA; Mutolo, D; Pantaleo, T | 1 |
| Gao, J; Gao, XY; Liao, ZH; Shi, Z; Wang, W; Zhong, MK; Zhou, LM; Zhu, GQ | 1 |
| Grothe, B; Koch, U; Magnusson, AK; Park, TJ; Pecka, M | 1 |
| Dehpour, AR; Karimian, SM; Mirzaii-Dizgah, I; Riahi, E; Roodsari, HR; Sadeghipour, HR | 1 |
| Esfandiari, B; Etemadi, L; Ghoshooni, H; Noroozzadeh, A; Pourmotabbed, A; Rostami, P; Sahraei, H; Salimi, SH; Shams, J; Zarrindast, MR | 1 |
| Luccini, E; Raiteri, L; Raiteri, M; Romei, C | 1 |
| Aleem, IS; Ashraf, A; Cortez, MA; Kanawaty, A; Liu, CC; Sadeghnia, HR; Shen, L; Snead, OC; Stewart, L; Trepanier, CH; Wu, Y | 1 |
| Sun, H; Wu, SH | 1 |
| Diwan, M; Lange, N; Nobrega, JN; Raymond, R; Richter, A; Richter, F; Sander, SE | 1 |
| Coop, A; France, CP; Koek, W; Mercer, SL | 1 |
| O'Rourke, ST; Qian, SY; Sun, C; Yao, F; Zhang, Q | 1 |
| Cheng, K; France, CP; Koek, W; Rice, KC | 1 |
| Chen, L; Luo, B; Su, YY; Wang, HT; Wu, SH | 1 |
| Arora, DS; Brodie, MS; McElvain, MA; Nimitvilai, S | 1 |
| Cheng, K; Koek, W; Rice, KC | 1 |
| Niere, F; Raab-Graham, KF; Workman, ER | 1 |
| Bisht, R; Kumar, P; Majeed, AB; Pant, J; Prakash, A; Tyagi, RK | 1 |
| Carvalho, P; de Vries, MG; Martins, I; Tavares, I; Teixeira-Pinto, A; Westerink, BHC; Wilson, SP | 1 |
| Chen, Q; Ding, L; Gao, R; Gao, XY; Kang, YM; Li, YH; Xiong, XQ; Zhu, GQ | 1 |
| Bogatyrev, S; Tzschentke, B; Yakimova, KS | 1 |
| Ramakrishna, Y; Sadeghi, SG | 1 |
194 other study(ies) available for cgp 35348 and baclofen
| Article | Year |
|---|---|
GABAB receptors in various in vitro and in vivo models of epilepsy: a study with the GABAB receptor blocker CGP 35348.
Topics: Animals; Baclofen; Convulsants; Epilepsy; GABA-A Receptor Antagonists; Hippocampus; In Vitro Techniques; Isoniazid; Male; Mice; Mice, Inbred Strains; Organophosphorus Compounds; Rats; Rats, Inbred Strains; Receptors, GABA-A | 1992 |
Involvement of intrathalamic GABAB neurotransmission in the control of absence seizures in the rat.
Topics: Animals; Baclofen; Electroencephalography; Epilepsy, Absence; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Male; Microinjections; Organophosphorus Compounds; Rats; Rats, Inbred Strains; Receptors, GABA-A; Synaptic Transmission; Thalamus; Time Factors | 1992 |
Evidence for GABAB-mediated mechanisms in experimental generalized absence seizures.
Topics: Animals; Baclofen; Behavior, Animal; Disease Models, Animal; Electroencephalography; Epilepsy, Absence; GABA-A Receptor Antagonists; Male; Organophosphorus Compounds; Rats; Rats, Inbred Strains; Receptors, GABA-A | 1992 |
The role of GABAB receptor activation in absence seizures of lethargic (lh/lh) mice.
Topics: Animals; Anticonvulsants; Baclofen; Disease Models, Animal; Dose-Response Relationship, Drug; Electroencephalography; Electrophysiology; Epilepsy, Absence; Hippocampus; In Vitro Techniques; Mice; Mice, Inbred Strains; Organophosphorus Compounds; Picrotoxin; Quinoxalines; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate | 1992 |
Effectiveness of GABAB antagonists in inhibiting baclofen-induced reductions in cytosolic free Ca concentration in isolated melanotrophs of rat.
Topics: Animals; Baclofen; Calcium; Cytosol; GABA-A Receptor Antagonists; In Vitro Techniques; Male; Organophosphorus Compounds; Pituitary Gland, Anterior; Rats; Rats, Inbred Strains | 1992 |
Experimental absence seizures: potential role of gamma-hydroxybutyric acid and GABAB receptors.
Topics: 4-Butyrolactone; Animals; Baclofen; Brain; Cyclic GMP; Disease Models, Animal; Epilepsy, Absence; GABA-A Receptor Antagonists; Male; Organophosphorus Compounds; Rats; Rats, Inbred Strains; Receptors, GABA-A; Reference Values; Reproducibility of Results; Sodium Oxybate; Valproic Acid | 1992 |
GABAB receptor antagonists: potential new anti-absence drugs.
Topics: Action Potentials; Administration, Oral; Animals; Baclofen; Blood-Brain Barrier; Disease Models, Animal; Epilepsy, Absence; GABA-A Receptor Antagonists; Injections, Intraperitoneal; Male; Organophosphorus Compounds; Rats; Rats, Inbred Strains | 1992 |
Blockade of GABAB receptors accelerates amygdala kindling development.
Topics: Amygdala; Animals; Baclofen; GABA-A Receptor Antagonists; Kindling, Neurologic; Male; Organophosphorus Compounds; Rats | 1992 |
Pharmacological characterization of GABAB-mediated responses in the CA1 region of the rat hippocampal slice.
Topics: Animals; Baclofen; Electrophysiology; GABA Antagonists; gamma-Aminobutyric Acid; Hippocampus; Neural Inhibition; Organophosphorus Compounds; Picrotoxin; Rats; Receptors, GABA-A | 1992 |
The action of GABAB antagonists in the trigeminal nucleus of the rat.
Topics: Animals; Baclofen; GABA-A Receptor Antagonists; Organophosphorus Compounds; Rats; Rats, Inbred Strains; Trigeminal Nuclei | 1992 |
Desensitization of GABAB receptors and antagonism by CGP 35348, prevent bicuculline- and picrotoxin-induced antinociception.
Topics: Analgesics; Animals; Baclofen; Bicuculline; Dose-Response Relationship, Drug; Drug Tolerance; GABA-A Receptor Antagonists; Injections, Intraventricular; Male; Mice; Motor Activity; Organophosphorus Compounds; Pain Measurement; Pentobarbital; Picrotoxin; Postural Balance; Rats; Rats, Inbred Strains; Receptors, GABA-A | 1992 |
Stimulation of high affinity gamma-aminobutyric acidB receptors potentiates the depolarization-induced increase of intraneuronal ionized calcium content in cerebellar granule neurons.
Topics: Animals; Baclofen; Calcium; Cells, Cultured; Cerebellum; Cytoplasmic Granules; Dantrolene; Drug Interactions; Egtazic Acid; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Intracellular Fluid; Membrane Potentials; Neurons; Organophosphorus Compounds; Potassium Channels; Rats; Receptors, GABA-A; Stimulation, Chemical | 1992 |
Proposed antagonists at GABAB receptors that inhibit adenylyl cyclase in cerebellar granule cell cultures of rat.
Topics: Adenylyl Cyclase Inhibitors; Amino Acids; Amino Acids, Neutral; Animals; Baclofen; Cells, Cultured; Cerebellum; Dose-Response Relationship, Drug; GABA-A Receptor Antagonists; Organophosphorus Compounds; Rats; Rats, Sprague-Dawley; Taurine | 1992 |
Participation of GABAergic systems in the production of antinociception by various stresses in mice.
Topics: Analgesia; Animals; Baclofen; Bicuculline; Dose-Response Relationship, Drug; Electroshock; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Male; Mice; Mice, Inbred Strains; Muscimol; Organophosphorus Compounds; Picrotoxin; Receptors, GABA-A; Stress, Psychological | 1992 |
GABAB receptor involvement in the control of genetic absence seizures in rats.
Topics: Animals; Baclofen; Brain Mapping; Cerebral Cortex; Epilepsy, Absence; Evoked Potentials; GABA-A Receptor Antagonists; Male; Neural Inhibition; Organophosphorus Compounds; Rats; Rats, Wistar; Receptors, GABA-A; Synaptic Transmission; Thalamic Nuclei | 1992 |
Modulation by GABAB receptors of spontaneous synchronous activities induced by 4-aminopyridine in the rat hippocampus.
Topics: 4-Aminopyridine; Animals; Baclofen; Dose-Response Relationship, Drug; Epilepsy; Evoked Potentials; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Hippocampus; In Vitro Techniques; Organophosphorus Compounds; Rats; Rats, Sprague-Dawley; Receptors, GABA-A | 1992 |
Differential activation of GABAA and GABAB receptors by spontaneously released transmitter.
Topics: Animals; Baclofen; Bicuculline; Electric Stimulation; GABA-A Receptor Antagonists; Hippocampus; In Vitro Techniques; Interneurons; Neurotransmitter Agents; Organophosphorus Compounds; Potassium Channels; Rats; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate; Synapses | 1992 |
Functional evidence for multiple gamma-aminobutyric acidB receptor subtypes in the rat cerebral cortex.
Topics: Animals; Baclofen; Cerebral Cortex; Chromatography, High Pressure Liquid; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Male; Organophosphorus Compounds; Peptides; Rats; Rats, Inbred Strains; Receptors, GABA-A | 1992 |
Pharmacologically distinct GABAB receptor subtypes modulate neurotransmitter release in the rat brain cortex.
Topics: Animals; Baclofen; Bicuculline; Cerebral Cortex; GABA-A Receptor Antagonists; Glutamates; Glutamic Acid; Muscimol; Neurotransmitter Agents; Organophosphorus Compounds; Rats; Receptors, GABA-A; Somatostatin; Synaptosomes | 1992 |
Systemic administration of baclofen and the GABAB antagonist, CGP 35348, does not affect GABA, glutamate or aspartate in microdialysates of the striatum of conscious rats.
Topics: Animals; Aspartic Acid; Baclofen; Corpus Striatum; Dialysis; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Male; Organophosphorus Compounds; Potassium; Rats; Rats, Inbred Strains | 1992 |
A comparison of the relative activities of a number of GABAB antagonists in the isolated vas deferens of the rat.
Topics: Animals; Baclofen; Dose-Response Relationship, Drug; GABA-B Receptor Antagonists; In Vitro Techniques; Male; Organophosphorus Compounds; Rats; Rats, Wistar; Vas Deferens | 1991 |
The GABAB antagonist, CGP 35348, antagonizes the effects of baclofen, gamma-butyrolactone and HA 966 on rat striatal dopamine synthesis.
Topics: 4-Butyrolactone; Animals; Baclofen; Corpus Striatum; Dihydroxyphenylalanine; Dopamine; GABA-A Receptor Antagonists; Haloperidol; Organophosphorus Compounds; Pyrrolidinones; Rats; Tetrabenazine | 1991 |
Inhibition of baclofen-induced hypothermia in mice by the novel GABAB antagonist CGP 35348.
Topics: Animals; Baclofen; Body Temperature; GABA-A Receptor Antagonists; Hypothermia; Male; Mice; Organophosphorus Compounds | 1991 |
CGP 35348, a new GABAB antagonist, prevents antinociception and muscle-relaxant effect induced by baclofen.
Topics: Analgesics; Animals; Baclofen; GABA Antagonists; GABA-A Receptor Antagonists; Injections, Intraventricular; Male; Mice; Morphine; Muscle Relaxation; Muscles; Organophosphorus Compounds; Oxotremorine; Postural Balance; Rats; Rats, Inbred Strains; Reaction Time | 1991 |
Baclofen analgesia in mice: a GABAB-mediated response.
Topics: Analgesia; Animals; Baclofen; Female; GABA-A Receptor Antagonists; Male; Mice; Naloxone; Organophosphorus Compounds; Pain; Pain Measurement; Receptors, GABA-A | 1991 |
Noradrenaline release in the rat vena cava is inhibited by gamma-aminobutyric acid via GABAB receptors but not affected by histamine.
Topics: Animals; Baclofen; Bicuculline; Corticosterone; Desipramine; Electric Stimulation; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Histamine; In Vitro Techniques; Male; Muscimol; Norepinephrine; Organophosphorus Compounds; Rats; Rats, Inbred Strains; Receptors, GABA-A; Vena Cava, Inferior; Yohimbine | 1991 |
Studies on pituitary melanotrophs reveal the novel GABAB antagonist CGP 35-348 to be the first such compound effective on endocrine cells.
Topics: Animals; Baclofen; Bicuculline; Darkness; GABA Antagonists; GABA-A Receptor Antagonists; Kinetics; Male; Melanocyte-Stimulating Hormones; Methionine; Muscimol; Organophosphorus Compounds; Pituitary Gland; Rats; Rats, Inbred Strains; Xenopus laevis | 1991 |
GABA autoreceptors regulate the induction of LTP.
Topics: 2-Chloroadenosine; Animals; Baclofen; Carbachol; Hippocampus; In Vitro Techniques; Membrane Potentials; Neuronal Plasticity; Organophosphorus Compounds; Rats; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate | 1991 |
Electrophysiological characterization of potent agonists and antagonists at pre- and postsynaptic GABAB receptors on neurones in rat brain slices.
Topics: Animals; Baclofen; Bicuculline; Brain; Corpus Striatum; Electrophysiology; GABA-A Receptor Antagonists; In Vitro Techniques; Membrane Potentials; Neurons; Organophosphorus Compounds; Rats; Receptors, GABA-A; Substantia Nigra; Synapses | 1990 |
The effects of baclofen and two GABAB-receptor antagonists on long-term potentiation.
Topics: Animals; Baclofen; Electric Stimulation; GABA-A Receptor Antagonists; Hippocampus; In Vitro Techniques; Male; Neurons; Organophosphorus Compounds; Rats; Rats, Inbred Strains; Synapses | 1990 |
CGP 35348: a centrally active blocker of GABAB receptors.
Topics: Adenylyl Cyclase Inhibitors; Animals; Animals, Newborn; Anticonvulsants; Baclofen; Behavior, Animal; Brain Chemistry; Cyclic AMP; Electrophysiology; Hippocampus; In Vitro Techniques; Iontophoresis; Organophosphorus Compounds; Postural Balance; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, GABA-A; Spinal Cord | 1990 |
Neural network of structures in which GABAB receptors regulate absence seizures in the lethargic (lh/lh) mouse model.
Topics: Animals; Autoradiography; Baclofen; Electroencephalography; Epilepsy, Absence; GABA Antagonists; GABA-B Receptor Agonists; Mice; Mice, Mutant Strains; Microinjections; Nerve Net; Organophosphorus Compounds; Receptors, GABA-B; Sleep Stages | 1995 |
GABAB receptors modulate synaptically-evoked responses in the rat dentate gyrus, in vivo.
Topics: Animals; Baclofen; Evoked Potentials; Female; GABA-B Receptor Agonists; GABA-B Receptor Antagonists; Hippocampus; Neural Inhibition; Organophosphorus Compounds; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Receptors, GABA-B | 1995 |
Age-dependent effects of gamma-aminobutyric acid agents on flurothyl seizures.
Topics: Age Factors; Animals; Anticonvulsants; Baclofen; Convulsants; Flurothyl; GABA Agents; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Male; Organophosphorus Compounds; Phenobarbital; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Receptors, GABA-B; Seizures; Vigabatrin | 1995 |
Extracellular GABA in the ventrolateral thalamus of rats exhibiting spontaneous absence epilepsy: a microdialysis study.
Topics: Animals; Baclofen; Electroencephalography; Epilepsy, Absence; Extracellular Space; GABA Antagonists; gamma-Aminobutyric Acid; Microdialysis; Nipecotic Acids; Organophosphorus Compounds; Potassium; Rats; Rats, Wistar; Stereoisomerism; Thalamus; Tiagabine | 1995 |
Intrathecal baclofen and muscimol, but not midazolam, are antinociceptive using the rat-formalin model.
Topics: Animals; Baclofen; Bicuculline; Drug Administration Schedule; Drug Interactions; GABA Agents; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; GABA-B Receptor Agonists; GABA-B Receptor Antagonists; Injections, Spinal; Male; Midazolam; Motor Activity; Muscimol; Nociceptors; Organophosphorus Compounds; Pain Measurement; Rats; Rats, Sprague-Dawley; Spinal Cord | 1995 |
Baclofen-induced block of the Hering-Breuer expiratory-promoting reflex in rats.
Topics: Animals; Baclofen; GABA Antagonists; Male; Organophosphorus Compounds; Rats; Rats, Wistar; Reflex; Respiration; Sodium Chloride; Time Factors; Trachea; Vagus Nerve | 1995 |
Characterization of GABAB ligands in vivo.
Topics: Animals; Baclofen; beta-Alanine; Drug Interactions; Female; GABA Antagonists; GABA-B Receptor Antagonists; Ligands; Mice; Mice, Inbred BALB C; Muscle Relaxation; Organophosphorus Compounds | 1995 |
Different mechanisms for use-dependent depression of two GABAA-mediated IPSCs in rat hippocampus.
Topics: Animals; Baclofen; Electrophysiology; GABA-A Receptor Antagonists; Hippocampus; Male; Organophosphorus Compounds; Patch-Clamp Techniques; Presynaptic Terminals; Rats; Rats, Sprague-Dawley; Receptors, GABA-A | 1995 |
Role of GABAB receptors in the control of hypoglossal motoneurons in vivo.
Topics: Animals; Baclofen; Blood Pressure; Dose-Response Relationship, Drug; GABA Antagonists; Hypoglossal Nerve; Microinjections; Motor Neurons; Organophosphorus Compounds; Rats; Rats, Sprague-Dawley; Receptors, GABA; Respiration | 1994 |
The GABAB antagonist CGP 35348 inhibits the effects of baclofen on sexual behavior and motor coordination.
Topics: Animals; Baclofen; GABA Antagonists; Male; Organophosphorus Compounds; Psychomotor Performance; Rats; Rats, Wistar; Sexual Behavior, Animal | 1995 |
Do GABAB receptors have a role in causing behavioural hyperexcitability, both during ethanol withdrawal and in naive mice?
Topics: Animals; Baclofen; Behavior, Animal; Ethanol; GABA-B Receptor Agonists; GABA-B Receptor Antagonists; Handling, Psychological; Male; Mice; Mice, Inbred Strains; Motor Activity; Organophosphorus Compounds; Receptors, GABA-B; Substance Withdrawal Syndrome | 1995 |
Respiratory effects of baclofen and 3-aminopropylphosphinic acid in guinea-pigs.
Topics: Administration, Inhalation; Analysis of Variance; Animals; Baclofen; Bicuculline; Carbon Dioxide; Dose-Response Relationship, Drug; Drug Interactions; GABA Agonists; GABA-A Receptor Antagonists; GABA-B Receptor Antagonists; Guinea Pigs; Injections, Intraventricular; Injections, Subcutaneous; Male; Naloxone; Organophosphorus Compounds; Pulmonary Ventilation; Respiration; Tidal Volume | 1995 |
Presynaptic gamma-hydroxybutyric acid (GHB) and gamma-aminobutyric acidB (GABAB) receptor-mediated release of GABA and glutamate (GLU) in rat thalamic ventrobasal nucleus (VB): a possible mechanism for the generation of absence-like seizures induced by GH
Topics: Action Potentials; Animals; Baclofen; Epilepsy, Absence; Extracellular Space; GABA-B Receptor Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Male; Organophosphorus Compounds; Potassium; Presynaptic Terminals; Rats; Rats, Sprague-Dawley; Receptors, Cell Surface; Receptors, GABA-B; Sodium Oxybate; Thalamic Nuclei | 1995 |
Pharmacology of the GABAB receptor in amphibian retina.
Topics: Ambystoma; Animals; Baclofen; Butylamines; Evoked Potentials; GABA-B Receptor Agonists; GABA-B Receptor Antagonists; In Vitro Techniques; Membrane Potentials; Necturus; Organophosphorus Compounds; Propylamines; Receptors, GABA-B; Retina; Retinal Ganglion Cells; Stereoisomerism; Structure-Activity Relationship | 1994 |
Characterization of the GABA autoreceptor in human neocortex as a pharmacological subtype of the GABAB receptor.
Topics: Adolescent; Adult; Aged; Animals; Baclofen; Benzylamines; Binding, Competitive; Brain Neoplasms; Cerebral Cortex; Female; GABA Agonists; GABA Antagonists; GABA-A Receptor Antagonists; GABA-B Receptor Agonists; GABA-B Receptor Antagonists; Humans; Male; Middle Aged; Organophosphorus Compounds; Phosphinic Acids; Rats; Receptors, GABA-B | 1994 |
Differences in the Cs block of baclofen and 4-aminopyridine induced potassium currents of guinea pig CA3 neurons in vitro.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Baclofen; GABA-B Receptor Antagonists; Guinea Pigs; Hippocampus; Organophosphorus Compounds; Potassium Channels; Receptors, GABA-B | 1994 |
The effects of GABAB ligands on alcohol withdrawal in mice.
Topics: Animals; Baclofen; Behavior, Animal; Diazepam; Dose-Response Relationship, Drug; Ethanol; Female; GABA Antagonists; GABA-B Receptor Antagonists; Mice; Mice, Inbred C57BL; Organophosphorus Compounds; Phenylalanine; Receptors, GABA-B; Seizures; Substance Withdrawal Syndrome; Tremor | 1994 |
Strain-dependent effects of post-training GABA receptor agonists and antagonists on memory storage in mice.
Topics: Animals; Avoidance Learning; Baclofen; Bicuculline; Dose-Response Relationship, Drug; Electroshock; GABA Agonists; GABA Antagonists; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; GABA-B Receptor Agonists; GABA-B Receptor Antagonists; Male; Memory; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Muscimol; Organophosphorus Compounds; Picrotoxin; Species Specificity | 1993 |
Excitatory cardiovascular and respiratory effects of baclofen in intact rats.
Topics: Animals; Baclofen; Blood Pressure; Electromyography; GABA-A Receptor Antagonists; Heart Rate; Male; Organophosphorus Compounds; Rats; Rats, Wistar; Respiration; Tidal Volume | 1994 |
Peripheral and central sites of action of GABA-B agonists to inhibit the cough reflex in the cat and guinea pig.
Topics: Animals; Antitussive Agents; Baclofen; Capsaicin; Cats; Central Nervous System; Codeine; Cough; GABA Agonists; GABA-B Receptor Agonists; GABA-B Receptor Antagonists; Guinea Pigs; In Vitro Techniques; Injections, Intraventricular; Male; Oligopeptides; Organophosphorus Compounds; Peripheral Nervous System | 1994 |
GABA and glutamate release affected by GABAB receptor antagonists with similar potency: no evidence for pharmacologically different presynaptic receptors.
Topics: Animals; Baclofen; Benzylamines; Cerebral Cortex; Electric Stimulation; GABA-A Receptor Antagonists; GABA-B Receptor Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; In Vitro Techniques; Male; Organophosphorus Compounds; Phosphinic Acids; Rats; Rats, Inbred Strains; Receptors, GABA-B; Receptors, Presynaptic | 1994 |
Omega-conotoxin sensitivity and presynaptic inhibition of glutamatergic sensory neurotransmission in vitro.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Animals; Baclofen; Calcium; Calcium Channel Blockers; Cells, Cultured; Chick Embryo; Evoked Potentials; GABA-A Receptor Antagonists; Ganglia, Spinal; Mollusk Venoms; Neurons, Afferent; omega-Conotoxin GVIA; Organophosphorus Compounds; Peptides; Quinoxalines; Spinal Cord; Synapses; Synaptic Transmission; Time Factors | 1994 |
Pharmacological discrimination between gamma-aminobutyric acid type B receptors regulating cholecystokinin and somatostatin release from rat neocortex synaptosomes.
Topics: Animals; Baclofen; Benzylamines; Cerebral Cortex; Cholecystokinin; GABA Agonists; GABA-A Receptor Antagonists; GABA-B Receptor Antagonists; gamma-Aminobutyric Acid; Ligands; Male; Organophosphorus Compounds; Phosphinic Acids; Rats; Rats, Sprague-Dawley; Receptors, GABA-B; Somatostatin; Synaptosomes | 1994 |
Glutamatergic hippocampal formation projections to prefrontal cortex in the rat are regulated by GABAergic inhibition and show convergence with glutamatergic projections from the limbic thalamus.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Animals; Baclofen; Bicuculline; Brain Mapping; Electric Stimulation; Electrophysiology; GABA-A Receptor Antagonists; GABA-B Receptor Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Limbic System; Male; Neurons; Organophosphorus Compounds; Piperazines; Prefrontal Cortex; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Thalamus | 1994 |
Effects of GABAB activation and inhibition on vestibulo-ocular and optokinetic responses in the pigmented rat.
Topics: Animals; Baclofen; Darkness; Dose-Response Relationship, Drug; GABA-B Receptor Agonists; GABA-B Receptor Antagonists; Injections, Intramuscular; Injections, Intraventricular; Nystagmus, Optokinetic; Organophosphorus Compounds; Rats; Rats, Inbred Strains; Reflex, Vestibulo-Ocular | 1994 |
gamma-Aminobutyric acid receptor-mediated regulation of periventricular-hypophysial dopaminergic neurons: possible role in mediating stress- and 5-hydroxytryptamine-induced decreases in neuronal activity.
Topics: 3,4-Dihydroxyphenylacetic Acid; alpha-MSH; Animals; Baclofen; Dopamine; Hypothalamus, Middle; Male; Organophosphorus Compounds; Pituitary Gland; Pyridazines; Rats; Receptors, GABA-A; Receptors, GABA-B; Serotonin; Stress, Physiological | 1994 |
Presynaptic actions of GABA and baclofen in CA1 region of the guinea-pig hippocampus in vitro.
Topics: Animals; Baclofen; Bicuculline; Calcium; Electrophysiology; GABA Antagonists; gamma-Aminobutyric Acid; Guinea Pigs; Hippocampus; In Vitro Techniques; Male; Membrane Potentials; Neuromuscular Depolarizing Agents; Organophosphorus Compounds; Picrotoxin; Receptors, Presynaptic; Sesterterpenes; Tetrodotoxin | 1994 |
GABA-B receptor-mediated spinal inhibition.
Topics: Afferent Pathways; Animals; Baclofen; Bicuculline; Cats; Decerebrate State; Depression, Chemical; GABA Antagonists; gamma-Aminobutyric Acid; Organophosphorus Compounds; Phosphinic Acids; Receptors, GABA; Reflex, Monosynaptic; Spinal Cord; Tetany | 1994 |
Blockade of thalamic GABAB receptors decreases EEG synchronization.
Topics: Animals; Baclofen; Cats; Cortical Synchronization; Electroencephalography; Electromyography; Electrooculography; GABA-B Receptor Antagonists; Microdialysis; Organophosphorus Compounds; Sleep; Thalamus; Wakefulness | 1994 |
Release of endogenous glutamic and aspartic acids from cerebrocortex synaptosomes and its modulation through activation of a gamma-aminobutyric acidB (GABAB) receptor subtype.
Topics: Animals; Aspartic Acid; Baclofen; Bicuculline; Cerebral Cortex; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Kinetics; Male; Organophosphorus Compounds; Picrotoxin; Potassium Chloride; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Synaptosomes | 1993 |
Discrimination of post- and presynaptic GABAB receptor-mediated responses by tetrahydroaminoacridine in area CA3 of the rat hippocampus.
Topics: 2-Amino-5-phosphonovalerate; Animals; Baclofen; Evoked Potentials; GABA-A Receptor Antagonists; Hippocampus; In Vitro Techniques; Male; Organophosphorus Compounds; Potassium Channels; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Synapses; Tacrine | 1993 |
GABAB autoreceptors mediate activity-dependent disinhibition and enhance signal transmission in the dentate gyrus.
Topics: 2-Amino-5-phosphonovalerate; Animals; Baclofen; Culture Techniques; GABA-A Receptor Antagonists; Hippocampus; Male; Membrane Potentials; Nerve Fibers; Neural Inhibition; Organophosphorus Compounds; Picrotoxin; Quinoxalines; Rats; Rats, Sprague-Dawley; Reaction Time; Receptors, GABA-A; Synaptic Transmission; Theta Rhythm | 1993 |
Intrathecal GABAB antagonists attenuate the antinociception produced by microinjection of L-glutamate into the ventromedial medulla of the rat.
Topics: Analgesics; Animals; Baclofen; Basal Ganglia; Behavior, Animal; Excitatory Amino Acid Antagonists; GABA Antagonists; GABA-A Receptor Antagonists; Glutamates; Glutamic Acid; Injections, Spinal; Medulla Oblongata; Methysergide; Microinjections; Organophosphorus Compounds; Raphe Nuclei; Rats; Rats, Sprague-Dawley; Reaction Time; Receptors, GABA-A; Skin Temperature | 1993 |
gamma-Hydroxybutyric acid (GHBA) induces pacemaker activity and inhibition of substantia nigra dopamine neurons by activating GABAB-receptors.
Topics: Animals; Baclofen; Biological Clocks; Dopamine; Dose-Response Relationship, Drug; Electrophysiology; GABA-B Receptor Antagonists; Injections, Intravenous; Male; Microelectrodes; Neurons; Organophosphorus Compounds; Rats; Rats, Sprague-Dawley; Sodium Oxybate; Substantia Nigra | 1993 |
A role for computer simulation in solving the riddles of autoreceptor-mediated regulation of GABA release.
Topics: Animals; Baclofen; Computer Simulation; GABA-B Receptor Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Kinetics; Neurotransmitter Uptake Inhibitors; Organophosphorus Compounds; Rats; Receptors, GABA; Receptors, GABA-B; Software | 1993 |
Antagonism of baclofen-induced depression of whole-cell synaptic currents in spinal dorsal horn neurones by the potent GABAB antagonist CGP55845.
Topics: Action Potentials; Animals; Animals, Newborn; Baclofen; Dose-Response Relationship, Drug; GABA-B Receptor Antagonists; Ganglia, Spinal; In Vitro Techniques; Neurons; Organophosphorus Compounds; Phosphinic Acids; Propanolamines; Rats; Spinal Cord; Synapses | 1993 |
The development of GABAB-mediated activity in the rat dentate gyrus.
Topics: Animals; Baclofen; Electric Stimulation; Evoked Potentials; GABA-A Receptor Antagonists; GABA-B Receptor Antagonists; Hippocampus; In Vitro Techniques; Organophosphorus Compounds; Rats; Receptors, GABA-A; Receptors, GABA-B | 1994 |
GABAB receptor-mediated mechanisms in the RVLM studied by microinjections of two GABAB receptor antagonists.
Topics: Animals; Baclofen; Blood Pressure; Electrocardiography; Functional Laterality; GABA-B Receptor Antagonists; Heart Rate; Homeostasis; Male; Medulla Oblongata; Microinjections; Muscimol; Organophosphorus Compounds; Rats; Rats, Wistar; Receptors, GABA-B | 1994 |
Antitussive effects of GABAB agonists in the cat and guinea-pig.
Topics: Animals; Antitussive Agents; Baclofen; Capsaicin; Cats; Codeine; Cough; Dextromethorphan; Electromyography; GABA Antagonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Guinea Pigs; Irritants; Male; Organophosphorus Compounds; Respiratory Muscles | 1993 |
GABAB receptor-mediated inhibition of forskolin-stimulated cyclic AMP accumulation in rat spinal cord.
Topics: Analgesics; Animals; Animals, Newborn; Baclofen; Capsaicin; Colforsin; Cyclic AMP; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Norepinephrine; Organophosphorus Compounds; Rats; Rats, Wistar; Receptors, GABA-B; Spinal Cord | 1993 |
Giant GABAB-mediated synaptic potentials induced by zinc in the rat hippocampus: paradoxical effects of zinc on the GABAB receptor.
Topics: Animals; Baclofen; Barium; Electric Stimulation; Electrophysiology; Evoked Potentials; GABA Antagonists; gamma-Aminobutyric Acid; Hippocampus; In Vitro Techniques; Ions; Organophosphorus Compounds; Rats; Rats, Wistar; Receptors, GABA; Synaptic Transmission; Zinc | 1993 |
Thienyl-GABA derivatives as specific baclofen agonists in the rat and cat spinal cord in vivo.
Topics: Animals; Baclofen; Cats; Electrophoresis; Evoked Potentials; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Organophosphorus Compounds; Rats; Rats, Wistar; Receptors, GABA; Receptors, GABA-B; Spinal Cord | 1993 |
Involvement of GABAB receptors in the regulation of the hypothalamo-pituitary-adrenocortical (HPA) axis in rats.
Topics: Adrenal Cortex; Adrenocorticotropic Hormone; Aldosterone; Animals; Baclofen; Corticosterone; GABA-B Receptor Antagonists; Hypothalamo-Hypophyseal System; In Vitro Techniques; Male; Organophosphorus Compounds; Pituitary-Adrenal System; Rats; Rats, Inbred Strains; Receptors, GABA-B | 1993 |
GABAB-receptor activation alters the firing pattern of dopamine neurons in the rat substantia nigra.
Topics: Animals; Baclofen; Dizocilpine Maleate; Dopamine; Dose-Response Relationship, Drug; Evoked Potentials; GABA-B Receptor Antagonists; gamma-Aminobutyric Acid; Male; Membrane Potentials; Muscimol; Neurons; Organophosphorus Compounds; Rats; Rats, Sprague-Dawley; Receptors, GABA-B; Substantia Nigra | 1993 |
Indications from Mn-quenching of Fura-2 fluorescence in melanotrophs that dopamine and baclofen close Ca channels that are spontaneously open but not those opened by high [K+]O; and that Cd preferentially blocks the latter.
Topics: Action Potentials; Animals; Baclofen; Cadmium; Calcium Channel Blockers; Calcium Channels; Dopamine; Fluorescence; Fura-2; gamma-Aminobutyric Acid; Male; Manganese; Nickel; Organophosphorus Compounds; Pertussis Toxin; Pituitary Gland; Potassium; Rats; Rats, Sprague-Dawley; Sodium Channels; Sulpiride; Tetrodotoxin; Virulence Factors, Bordetella | 1993 |
Effects of GABAB receptor agonists and antagonists on the bulbar respiratory network in cat.
Topics: Animals; Baclofen; Cats; Decerebrate State; Dizocilpine Maleate; Evoked Potentials; Extracellular Space; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Iontophoresis; Medulla Oblongata; Nerve Net; Organophosphorus Compounds; Plethysmography; Receptors, GABA-A; Respiration | 1993 |
Antagonism of L-baclofen-induced antinociception by CGP 35348 in the spinal cord of the rat.
Topics: Analgesics; Animals; Baclofen; Dose-Response Relationship, Drug; GABA-A Receptor Antagonists; Hot Temperature; Injections, Spinal; Isonicotinic Acids; Male; Nociceptors; Organophosphorus Compounds; Pain Measurement; Pain Threshold; Postural Balance; Rats; Rats, Sprague-Dawley; Reflex; Spinal Cord | 1993 |
gamma-Aminobutyric acid (GABA) autoreceptors in rat cerebral cortex and spinal cord represent pharmacologically distinct subtypes of the GABAB receptor.
Topics: Animals; Baclofen; Cerebral Cortex; gamma-Aminobutyric Acid; Male; Organophosphorus Compounds; Potassium; Rats; Rats, Wistar; Receptors, GABA-A; Spinal Cord; Synaptosomes | 1993 |
Effects of post-training administration of (-)-baclofen and chlordiazepoxide on memory retention in ICRC Swiss mice: interactions with GABAA and GABAB receptor antagonists.
Topics: Animals; Baclofen; Chlordiazepoxide; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Isomerism; Male; Memory; Mice; Mice, Inbred ICR; Motor Activity; Organophosphorus Compounds; Picrotoxin; Receptors, GABA-A | 1993 |
3-amino-2-(4-chlorophenyl)-nitropropane is a new GABAB receptor agonist, more active peripherally.
Topics: Animals; Baclofen; Brain; GABA-A Receptor Antagonists; Guinea Pigs; Male; Muscle Contraction; Muscle, Smooth; Nitro Compounds; Organophosphorus Compounds; Propylamines; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Vas Deferens | 1993 |
CGP 35348 blocks noradrenaline-release-inhibiting GABAB receptors in the pig retina, rat vena cava and pithed rat vasculature.
Topics: Animals; Baclofen; Blood Pressure; Blood Vessels; Decerebrate State; Dose-Response Relationship, Drug; In Vitro Techniques; Norepinephrine; Organophosphorus Compounds; Pyridazines; Rats; Receptors, GABA-A; Retina; Swine; Venae Cavae | 1993 |
(+/-)Baclofen sensitive scopolamine-induced short-term memory deficits in mice.
Topics: Animals; Baclofen; Dose-Response Relationship, Drug; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Memory, Short-Term; Mice; Mice, Inbred Strains; Organophosphorus Compounds; Receptors, GABA-A; Scopolamine | 1993 |
Pharmacological characterization of pre- and postsynaptic GABAB receptors in the deep nuclei of rat cerebellar slices.
Topics: Animals; Baclofen; Cerebellar Nuclei; Electrophysiology; GABA Agonists; GABA Antagonists; GABA-B Receptor Agonists; GABA-B Receptor Antagonists; gamma-Aminobutyric Acid; GTP-Binding Proteins; In Vitro Techniques; Male; Membrane Potentials; Organophosphorus Compounds; Patch-Clamp Techniques; Purkinje Cells; Rats; Rats, Wistar; Receptors, GABA-B; Receptors, Neurotransmitter | 1995 |
Role of gamma-aminobutyric acid B receptors in baroreceptor reflexes in hypertensive rats.
Topics: Animals; Baclofen; Baroreflex; Desoxycorticosterone; Electric Stimulation; Evoked Potentials; GABA Antagonists; Hemodynamics; Male; Organophosphorus Compounds; Pressoreceptors; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, GABA; Solitary Nucleus; Sympathetic Nervous System | 1996 |
Baclofen attenuates cardiorespiratory effects of vagal C fiber stimulation in rats.
Topics: Animals; Baclofen; Biguanides; GABA Antagonists; GABA-B Receptor Antagonists; Male; Nerve Fibers; Organophosphorus Compounds; Rats; Rats, Wistar; Serotonin Receptor Agonists; Vagus Nerve | 1995 |
Age-specific effects of baclofen on pentylenetetrazol-induced seizures in developing rats.
Topics: Age Factors; Animals; Animals, Newborn; Baclofen; Dose-Response Relationship, Drug; Epilepsy, Tonic-Clonic; GABA Antagonists; gamma-Aminobutyric Acid; Injections, Intraperitoneal; Male; Organophosphorus Compounds; Pentylenetetrazole; Rats; Rats, Sprague-Dawley; Receptors, GABA; Seizures | 1996 |
Antinociception produced by systemic R(+)-baclofen hydrochloride is attenuated by CGP 35348 administered to the spinal cord or ventromedial medulla of rats.
Topics: Analgesics, Non-Narcotic; Animals; Baclofen; Basal Ganglia; Catheterization; GABA Antagonists; GABA-B Receptor Antagonists; Injections, Spinal; Injections, Subcutaneous; Male; Medulla Oblongata; Microinjections; Organophosphorus Compounds; Pain Measurement; Raphe Nuclei; Rats; Rats, Sprague-Dawley; Reaction Time; Spinal Cord; Stereoisomerism | 1996 |
Role of peripheral GABAB receptors in the regulation of pepsinogen secretion in anaesthetized rats.
Topics: Anesthesia; Animals; Baclofen; Capsaicin; GABA Agonists; GABA Antagonists; GABA-B Receptor Agonists; GABA-B Receptor Antagonists; Gastric Mucosa; Male; Organophosphorus Compounds; p-Methoxy-N-methylphenethylamine; Pepsinogens; Perfusion; Rats; Rats, Wistar; Receptors, GABA-B; Vagotomy | 1995 |
Electrophysiological actions of GABAB agonists and antagonists in rat dorso-lateral septal neurones in vitro.
Topics: Analysis of Variance; Animals; Baclofen; Benzylamines; Dose-Response Relationship, Drug; Electrophysiology; GABA Agonists; GABA Antagonists; GABA-B Receptor Antagonists; In Vitro Techniques; Male; Membrane Potentials; Organophosphorus Compounds; Phosphinic Acids; Propanolamines; Rats; Receptors, GABA-B; Septal Nuclei | 1996 |
GABAB receptor-mediated responses in GABAergic projection neurones of rat nucleus reticularis thalami in vitro.
Topics: Animals; Baclofen; Electrophysiology; Evoked Potentials; Female; GABA Agonists; GABA Antagonists; GABA-B Receptor Agonists; GABA-B Receptor Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Membrane Potentials; Neural Pathways; Neurons; Organophosphorus Compounds; Patch-Clamp Techniques; Potassium Channels; Rats; Rats, Sprague-Dawley; Receptors, GABA-B; Receptors, Presynaptic; Thalamic Nuclei | 1996 |
GABA-induced responses in electrophysiologically characterized neurons within the rat rostro-ventrolateral medulla in vitro.
Topics: Animals; Baclofen; Bicuculline; Brain Stem; Electrophysiology; GABA Agonists; GABA Antagonists; GABA-A Receptor Antagonists; GABA-B Receptor Antagonists; gamma-Aminobutyric Acid; Heart Conduction System; In Vitro Techniques; Medulla Oblongata; Neurons; Organophosphorus Compounds; Picrotoxin; Pyridazines; Rats; Rats, Wistar; Synapses | 1996 |
Effects of GABAB receptor antagonists on two models of focal epileptogenesis.
Topics: Animals; Baclofen; Disease Models, Animal; Epilepsies, Partial; GABA Antagonists; GABA-B Receptor Antagonists; Male; Organophosphorus Compounds; Rats; Rats, Wistar; Time Factors | 1995 |
CGP 35348 and CGP 55845A block the baclofen-induced depression of dorsal root evoked potentials in lumbar motoneurons of the neonatal rat.
Topics: Animals; Animals, Newborn; Baclofen; Decerebrate State; Depression, Chemical; Evoked Potentials; GABA Agonists; GABA Antagonists; GABA-B Receptor Agonists; GABA-B Receptor Antagonists; Ganglia, Spinal; Motor Neurons; Organophosphorus Compounds; Phosphinic Acids; Propanolamines; Rats; Rats, Wistar; Reflex, Monosynaptic; Spinal Cord; Synaptic Membranes | 1996 |
Gamma-hydroxybutyric acid decreases thalamic sensory excitatory postsynaptic potentials by an action on presynaptic GABAB receptors.
Topics: Adjuvants, Anesthesia; Animals; Anticonvulsants; Baclofen; Benzocycloheptenes; Bicuculline; Dose-Response Relationship, Drug; Electrophysiology; GABA Agonists; GABA Antagonists; GABA-B Receptor Agonists; Geniculate Bodies; Male; Neurons, Afferent; Organophosphorus Compounds; Presynaptic Terminals; Rats; Rats, Wistar; Receptors, GABA-B; Sodium Oxybate; Synaptic Transmission | 1996 |
Relation of the [3H] gamma-hydroxybutyric acid (GHB) binding site to the gamma-aminobutyric acidB (GABAB) receptor in rat brain.
Topics: Animals; Autoradiography; Baclofen; Benzocycloheptenes; Binding Sites; Brain; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Guanosine Triphosphate; In Vitro Techniques; Male; Organophosphorus Compounds; Rats; Rats, Sprague-Dawley; Receptors, GABA-B; Seizures; Sodium Oxybate; Stereoisomerism | 1996 |
GABAergic characteristics of transcallosal activity of cat motor cortical neurons.
Topics: Animals; Baclofen; Bicuculline; Cats; GABA Antagonists; gamma-Aminobutyric Acid; Membrane Potentials; Motor Cortex; Organophosphorus Compounds | 1996 |
The GABAB-receptor antagonist, CGP 35348, antagonises gamma-hydroxybutyrate- and baclofen-induced alterations in locomotor activity and forebrain dopamine levels in mice.
Topics: Animals; Baclofen; Depression, Chemical; Dopamine; Dose-Response Relationship, Drug; GABA Agonists; GABA Antagonists; GABA-B Receptor Antagonists; Male; Mice; Motor Activity; Organophosphorus Compounds; Prosencephalon; Sodium Oxybate | 1996 |
In vivo blockade of thalamic GABA(B) receptors increases excitatory amino-acid levels.
Topics: Animals; Aspartic Acid; Baclofen; GABA-B Receptor Antagonists; Glutamic Acid; Male; Microdialysis; Organophosphorus Compounds; Rats; Rats, Wistar; Receptors, GABA-B; Taurine; Thalamus | 1996 |
Responses of rat substantia nigra dopamine-containing neurones to (-)-HA-966 in vitro.
Topics: Animals; Baclofen; Dopamine; Electrophysiology; Excitatory Amino Acid Agonists; GABA Agonists; Male; Neurons; Organophosphorus Compounds; Pyrrolidinones; Rats; Rats, Sprague-Dawley; Receptors, GABA-B; Substantia Nigra | 1997 |
Excitatory acoustic responses in the inferior colliculus of the rat are increased by GABAB receptor blockade.
Topics: Acoustic Stimulation; Action Potentials; Animals; Baclofen; GABA Antagonists; GABA-B Receptor Antagonists; Inferior Colliculi; Iontophoresis; Male; Neurons; Organophosphorus Compounds; Rats; Rats, Inbred Strains; Receptors, GABA-B; Time Factors | 1996 |
Tonic activation of presynaptic GABA(B) receptors on thalamic sensory afferents.
Topics: Animals; Baclofen; GABA Antagonists; Male; Neurons, Afferent; Organophosphorus Compounds; Presynaptic Terminals; Rats; Rats, Wistar; Receptors, GABA-A; Thalamus | 1996 |
A study on the involvement of GABAB receptor ligands in stress-induced antinociception in male mice.
Topics: Analgesia; Animals; Baclofen; GABA Agonists; GABA Antagonists; GABA-B Receptor Agonists; GABA-B Receptor Antagonists; Male; Mice; Mice, Inbred Strains; Organophosphorus Compounds; Pain Measurement; Reaction Time; Receptors, GABA-B; Restraint, Physical; Stress, Physiological; Swimming | 1997 |
High intracellular Cl- concentrations depress G-protein-modulated ionic conductances.
Topics: Animals; Baclofen; Chlorides; Cortical Spreading Depression; Dose-Response Relationship, Drug; Electric Conductivity; GABA Agonists; GABA Antagonists; GABA-B Receptor Agonists; GABA-B Receptor Antagonists; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Male; Membrane Potentials; Organophosphorus Compounds; Patch-Clamp Techniques; Potassium Chloride; Rats; Rats, Sprague-Dawley; Receptors, GABA-B; Serotonin; Synapses | 1997 |
Differential regulation of neocortical synapses by neuromodulators and activity.
Topics: Animals; Baclofen; Cholinergic Fibers; GABA Agonists; GABA Antagonists; GABA-B Receptor Agonists; Mecamylamine; Mice; Mice, Inbred Strains; Muscarinic Agonists; Neocortex; Neurons, Afferent; Neurotransmitter Agents; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Organophosphorus Compounds; Pyramidal Cells; Rats; Rats, Wistar; Synapses; Synaptic Transmission; Thalamus | 1997 |
Functional properties of perigeniculate inhibition of dorsal lateral geniculate nucleus thalamocortical neurons in vitro.
Topics: Acetazolamide; Animals; Anticonvulsants; Baclofen; Bicuculline; Cerebral Cortex; Convulsants; Electrophysiology; Female; Ferrets; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Geniculate Bodies; Male; Membrane Potentials; Neural Inhibition; Neural Pathways; Neurons; Organophosphorus Compounds; Picrotoxin; Receptors, GABA-A; Receptors, GABA-B; Receptors, Presynaptic; Thalamic Nuclei | 1997 |
Inhibitory interactions between perigeniculate GABAergic neurons.
Topics: Acetazolamide; Action Potentials; Animals; Anticonvulsants; Axons; Baclofen; Bicuculline; Calcium; Cerebral Cortex; Excitatory Postsynaptic Potentials; Female; Ferrets; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Geniculate Bodies; Glutamic Acid; Male; Muscimol; Neural Inhibition; Neurons; Organophosphorus Compounds; Picrotoxin; Receptors, GABA-A; Receptors, GABA-B; Receptors, Presynaptic; Tetrodotoxin; Thalamic Nuclei | 1997 |
Different roles for GABAA and GABAB receptors in visual processing in the rat superior colliculus.
Topics: Animals; Baclofen; Bicuculline; GABA Agonists; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; GABA-B Receptor Agonists; GABA-B Receptor Antagonists; gamma-Aminobutyric Acid; Habituation, Psychophysiologic; Iontophoresis; Organophosphorus Compounds; Photic Stimulation; Rats; Receptors, GABA-A; Receptors, GABA-B; Superior Colliculi; Vision, Ocular; Visual Fields | 1997 |
Presynaptic GABAB and adenosine A1 receptors regulate synaptic transmission to rat substantia nigra reticulata neurones.
Topics: Adenosine; Animals; Baclofen; Electrophysiology; GABA Antagonists; GABA-B Receptor Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; In Vitro Techniques; Neurons; Organophosphorus Compounds; Patch-Clamp Techniques; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Receptors, GABA-B; Receptors, Glutamate; Receptors, Purinergic P1; Substantia Nigra; Synaptic Transmission; Xanthines | 1997 |
EPSP amplitude modulation at the rat Ia-alpha motoneuron synapse: effects of GABAB receptor agonists and antagonists.
Topics: Afferent Pathways; Animals; Baclofen; Brachial Plexus; Electric Stimulation; Electroshock; Excitatory Postsynaptic Potentials; GABA Antagonists; GABA-B Receptor Agonists; GABA-B Receptor Antagonists; Male; Median Nerve; Motor Neurons; Muscle, Skeletal; Organophosphorus Compounds; Rats; Rats, Sprague-Dawley; Receptors, GABA-B; Regression Analysis; Spinal Cord; Synapses | 1998 |
Slow synaptic inhibition in nucleus HVc of the adult zebra finch.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Acoustic Stimulation; Action Potentials; Age Factors; Animals; Auditory Pathways; Baclofen; Birds; Cadmium; Evoked Potentials, Auditory; Excitatory Amino Acid Antagonists; GABA Agonists; GABA Antagonists; Learning; Male; Neural Inhibition; Organophosphorus Compounds; Receptors, GABA-A; Receptors, GABA-B; Synapses; Tetrodotoxin; Time Factors; Vocalization, Animal | 1998 |
Effects of baclofen on the Hering-Breuer inspiratory-inhibitory and deflation reflexes in rats.
Topics: Animals; Baclofen; Diaphragm; Electromyography; GABA Agonists; GABA Antagonists; Male; Organophosphorus Compounds; Rats; Rats, Wistar; Receptors, GABA; Reflex; Respiration; Solitary Nucleus | 1998 |
Ontogenesis of presynaptic GABAB receptor-mediated inhibition in the CA3 region of the rat hippocampus.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Aging; Animals; Animals, Newborn; Baclofen; Calcium; Electric Stimulation; Evoked Potentials; GABA Antagonists; gamma-Aminobutyric Acid; Hippocampus; In Vitro Techniques; Male; Neurotransmitter Uptake Inhibitors; Nipecotic Acids; Organophosphorus Compounds; Pyramidal Cells; Rats; Rats, Wistar; Receptors, GABA-B; Synaptic Transmission; Tiagabine | 1998 |
GABAB receptor-mediated inhibition of GABAA receptor calcium elevations in developing hypothalamic neurons.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Baclofen; Bicuculline; Calcium; Cells, Cultured; Embryo, Mammalian; GABA Antagonists; GABA-B Receptor Antagonists; Hypothalamus; Neurons; Organophosphorus Compounds; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Receptors, GABA-B; Synapses | 1998 |
Activation of presynaptic GABAB receptors inhibits evoked IPSCs in rat magnocellular neurons in vitro.
Topics: Animals; Baclofen; Evoked Potentials; Excitatory Postsynaptic Potentials; GABA Antagonists; Hypothalamus; In Vitro Techniques; Membrane Potentials; Neurons; Nipecotic Acids; Organophosphorus Compounds; Oximes; Patch-Clamp Techniques; Pertussis Toxin; Rats; Rats, Sprague-Dawley; Reaction Time; Receptors, GABA-B; Supraoptic Nucleus; Virulence Factors, Bordetella | 1998 |
Functional organization of rat olfactory bulb glomeruli revealed by optical imaging.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Baclofen; Bicuculline; Calcium; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Image Processing, Computer-Assisted; Male; N-Methylaspartate; Olfactory Bulb; Organ Culture Techniques; Organophosphorus Compounds; Presynaptic Terminals; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Stimulation, Chemical; Tetrodotoxin | 1998 |
Activation of inwardly rectifying K+ channels by GABA-B receptors expressed in Xenopus oocytes.
Topics: Animals; Baclofen; Cerebellum; Female; G Protein-Coupled Inwardly-Rectifying Potassium Channels; GABA Antagonists; GTP-Binding Proteins; Membrane Potentials; Muscimol; Oocytes; Organophosphorus Compounds; Patch-Clamp Techniques; Potassium Channels; Potassium Channels, Inwardly Rectifying; Rats; Receptors, GABA-B; Recombinant Proteins; Xenopus laevis | 1998 |
Inhibition of N- and P/Q-type calcium channels by postsynaptic GABAB receptor activation in rat supraoptic neurones.
Topics: Animals; Baclofen; Calcium Channel Blockers; Calcium Channels; GABA Antagonists; Guanosine Diphosphate; In Vitro Techniques; Male; Membrane Potentials; Neurons; Organophosphorus Compounds; Patch-Clamp Techniques; Pertussis Toxin; Phosphinic Acids; Propanolamines; Rats; Rats, Wistar; Receptors, GABA-B; Supraoptic Nucleus; Synapses; Synaptic Transmission; Thionucleotides; Virulence Factors, Bordetella | 1998 |
Post- and presynaptic GABA(B) receptor activation in neonatal rat rostral ventrolateral medulla neurons in vitro.
Topics: Animals; Animals, Newborn; Baclofen; Calcium; Chelating Agents; Egtazic Acid; Electric Stimulation; Excitatory Postsynaptic Potentials; GABA Agonists; GABA Antagonists; Guanosine Diphosphate; In Vitro Techniques; Medulla Oblongata; Neurons; Organophosphorus Compounds; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Receptors, GABA-B; Tetraethylammonium; Tetrodotoxin; Thionucleotides | 1998 |
GABA(B) receptor activation changes membrane and filter properties of auditory thalamic neurons.
Topics: Animals; Baclofen; Cadmium; Dose-Response Relationship, Drug; GABA Agonists; GABA Antagonists; GABA-B Receptor Agonists; GABA-B Receptor Antagonists; Geniculate Bodies; Guanosine 5'-O-(3-Thiotriphosphate); Neurons; Organophosphorus Compounds; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Synaptic Transmission; Tetrodotoxin; Thalamus; Vestibulocochlear Nerve | 1998 |
Involvement of GABA(A) and GABA(B) receptors in the mediation of discriminative stimulus effects of gamma-hydroxybutyric acid.
Topics: Anesthetics, Intravenous; Animals; Baclofen; Diazepam; Discrimination, Psychological; Dizocilpine Maleate; Dose-Response Relationship, Drug; Food; GABA Agonists; GABA Antagonists; GABA Modulators; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; GABA-B Receptor Agonists; GABA-B Receptor Antagonists; Male; Organophosphorus Compounds; Rats; Receptors, GABA-A; Receptors, GABA-B; Reinforcement, Psychology; Sodium Oxybate | 1998 |
[Improvement of learning and memory functions by GABAB receptor antagonists in mice].
Topics: Animals; Baclofen; Female; GABA Antagonists; Learning; Male; Memory; Mice; Organophosphorus Compounds | 1996 |
GABA(B) receptors as potential targets for drugs able to prevent excessive excitatory amino acid transmission in the spinal cord.
Topics: Animals; Autoreceptors; Baclofen; Drug Interactions; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Male; Organophosphorus Compounds; Presynaptic Terminals; Rats; Rats, Wistar; Receptors, GABA-B; Spinal Cord; Synaptosomes | 1998 |
A powerful GABA(B) receptor-mediated inhibition of GABAergic neurons in the arcuate nucleus.
Topics: Animals; Arcuate Nucleus of Hypothalamus; Baclofen; Dose-Response Relationship, Drug; Electrophysiology; Female; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Guinea Pigs; In Situ Hybridization, Fluorescence; In Vitro Techniques; Neural Inhibition; Neurons; Organophosphorus Compounds; Receptors, GABA-B | 1998 |
Presynaptic GABAergic control of the locomotor drive in the isolated spinal cord of neonatal rats.
Topics: Animals; Animals, Newborn; Baclofen; Electrophysiology; Excitatory Amino Acid Agonists; Free Radical Scavengers; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Locomotion; Membrane Potentials; Mephenesin; Muscimol; Muscle Relaxants, Central; N-Methylaspartate; Neural Inhibition; Organophosphorus Compounds; Presynaptic Terminals; Rats; Rats, Wistar; Receptors, GABA-A; Receptors, GABA-B; Serotonin; Spinal Cord; Tetrodotoxin | 1999 |
The reduction in paired-pulse inhibition in the rat hippocampus by gabapentin is independent of GABA(B) receptor receptor activation.
Topics: Acetates; Amines; Animals; Anticonvulsants; Baclofen; Cyclohexanecarboxylic Acids; Dentate Gyrus; Electric Stimulation; GABA Agonists; GABA Antagonists; Gabapentin; gamma-Aminobutyric Acid; Male; Neural Inhibition; Organophosphorus Compounds; Rats; Rats, Sprague-Dawley; Receptors, GABA-B | 1999 |
GABA(B) receptor-mediated stimulation of adenylyl cyclase activity in membranes of rat olfactory bulb.
Topics: Adenylate Cyclase Toxin; Adenylyl Cyclases; Animals; Baclofen; Calcium; Calmodulin; Colforsin; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; GABA Agonists; GABA Antagonists; GABA-B Receptor Agonists; GABA-B Receptor Antagonists; In Vitro Techniques; Indomethacin; Injections, Intraventricular; Male; Membranes; Neuropeptides; Neuroprotective Agents; Olfactory Bulb; Organophosphorus Compounds; Pertussis Toxin; Phosphinic Acids; Phospholipases A; Phospholipids; Pituitary Adenylate Cyclase-Activating Polypeptide; Propanolamines; Propylamines; Quinacrine; Rats; Rats, Sprague-Dawley; Receptors, GABA-B; Transducin; Virulence Factors, Bordetella | 1999 |
Tiagabine antinociception in rodents depends on GABA(B) receptor activation: parallel antinociception testing and medial thalamus GABA microdialysis.
Topics: Abdomen; Animals; Baclofen; Constriction, Pathologic; Dose-Response Relationship, Drug; Escape Reaction; Extracellular Space; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Male; Mice; Microdialysis; Naloxone; Narcotic Antagonists; Neurotransmitter Uptake Inhibitors; Nipecotic Acids; Nociceptors; Organophosphorus Compounds; Pain; Pain Measurement; Pain Threshold; Psychomotor Performance; Receptors, GABA-B; Thalamus; Tiagabine | 1999 |
Baclofen and antidepressant--induced antinociception in formalin test: possible GABA(B) mechanism involvement.
Topics: Analgesics, Non-Narcotic; Animals; Antidepressive Agents; Baclofen; GABA Agonists; Male; Mice; Organophosphorus Compounds; Receptors, GABA-B | 1999 |
Contribution of GABA(A) and GABA(B) receptors to the discriminative stimulus produced by gamma-hydroxybutyric acid.
Topics: 3-Hydroxybutyric Acid; Animals; Baclofen; Cues; Diazepam; Discrimination, Psychological; Dose-Response Relationship, Drug; GABA Agonists; GABA Antagonists; GABA Modulators; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; GABA-B Receptor Agonists; GABA-B Receptor Antagonists; Male; Motor Activity; Organophosphorus Compounds; Rats; Rats, Long-Evans; Receptors, GABA-A; Receptors, GABA-B; Stimulation, Chemical | 1999 |
Effects of GABAergic system on naloxone-induced jumping in morphine-dependent mice.
Topics: Animals; Baclofen; Behavior, Animal; Bicuculline; GABA Agonists; GABA Antagonists; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Injections, Intraventricular; Male; Mice; Morphine Dependence; Muscimol; Naloxone; Narcotic Antagonists; Organophosphorus Compounds; Picrotoxin; Substance Withdrawal Syndrome | 1999 |
A powerful GABA(B) receptor-mediated inhibition of GABAergic neurons in arcuate nucleus.
Topics: Animals; Arcuate Nucleus of Hypothalamus; Baclofen; Female; Fluorescent Antibody Technique; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Guinea Pigs; In Situ Hybridization; In Vitro Techniques; Neural Inhibition; Neurons; Organophosphorus Compounds; Receptors, GABA-B | 1999 |
GABA(B) receptor activation inhibits N- and P/Q-type calcium channels in cultured lamprey sensory neurons.
Topics: Animals; Baclofen; Calcium Channels, N-Type; Cells, Cultured; GABA Agonists; GABA Antagonists; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Lampreys; Membrane Potentials; Neurons, Afferent; Organophosphorus Compounds; Receptors, GABA-B | 1999 |
Baclofen and midazolam alter c-fos induction by peripheral noxious or innocuous stimulation in the spinal cord of normal and monoarthritic rats.
Topics: Animals; Arthritis, Experimental; Baclofen; Flumazenil; GABA Agonists; GABA Antagonists; GABA Modulators; Genes, fos; Male; Midazolam; Organophosphorus Compounds; Physical Stimulation; Rats; Rats, Wistar; Spinal Cord; Stimulation, Chemical | 1999 |
Effects of inhibitory neurotransmitters on the mudpuppy (Necturus maculatus) locomotor pattern in vitro.
Topics: Animals; Baclofen; Bicuculline; Electromyography; Excitatory Amino Acid Agonists; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Glycine; In Vitro Techniques; Locomotion; Membrane Potentials; N-Methylaspartate; Necturus; Neural Inhibition; Organophosphorus Compounds; Receptors, GABA-A; Receptors, GABA-B; Spinal Cord | 1999 |
Baclofen-induced antinociception and nicotinic receptor mechanism(s).
Topics: Analgesics; Animals; Baclofen; Dose-Response Relationship, Drug; Drug Interactions; GABA Antagonists; Hexamethonium; Male; Mice; Nicotine; Organophosphorus Compounds; Pain Measurement; Receptors, Nicotinic; Time Factors | 1999 |
Ethanol modulation of gamma-aminobutyric acid (GABA)-mediated inhibition of cerebellar Purkinje neurons: relationship to GABAb receptor input.
Topics: Animals; Baclofen; Central Nervous System Depressants; Cerebellum; Ethanol; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Male; Organophosphorus Compounds; Purkinje Cells; Rats; Rats, Sprague-Dawley; Receptors, GABA-B | 2000 |
GABA mediates presynaptic inhibition at glycinergic synapses in a rat auditory brainstem nucleus.
Topics: Animals; Baclofen; Carrier Proteins; Cochlear Nucleus; Electrophysiology; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Glycine; Glycine Agents; Immunohistochemistry; In Vitro Techniques; Membrane Proteins; Organophosphorus Compounds; Patch-Clamp Techniques; Presynaptic Terminals; Rats; Rats, Wistar; Receptors, GABA-A; Receptors, Glycine; Strychnine | 2000 |
Local GABAergic modulation of acetylcholine release from the cortex of freely moving rats.
Topics: Acetylcholine; Animals; Baclofen; Bicuculline; Brain Chemistry; Cerebral Cortex; Cholinesterase Inhibitors; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Locomotion; Male; Microdialysis; Muscimol; Organophosphorus Compounds; Physostigmine; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Receptors, GABA-B | 2000 |
Tonic and synaptically evoked presynaptic inhibition of sensory input to the rat olfactory bulb via GABA(B) heteroreceptors.
Topics: Animals; Baclofen; Excitatory Postsynaptic Potentials; GABA Agonists; GABA Antagonists; GABA-B Receptor Agonists; GABA-B Receptor Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Interneurons; Neural Inhibition; Olfactory Bulb; Olfactory Nerve; Olfactory Pathways; Organophosphorus Compounds; Presynaptic Terminals; Rats; Rats, Wistar; Reaction Time; Receptors, AMPA; Receptors, GABA-B; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission | 2000 |
GABA(B) receptor mechanism and imipramine-induced antinociception in ligated and non-ligated mice.
Topics: Analgesics, Opioid; Animals; Antidepressive Agents, Tricyclic; Baclofen; GABA Agonists; GABA Antagonists; Imipramine; Ligation; Male; Mice; Morphine; Organophosphorus Compounds; Pain Measurement; Receptors, GABA-B; Sciatic Nerve | 2000 |
Heterogeneous susceptibility of GABA(A) receptor-mediated IPSCs to depolarization-induced suppression of inhibition in rat hippocampus.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Animals; Baclofen; Carbachol; Cholinergic Agents; Diuretics; Electric Stimulation; Excitatory Amino Acid Antagonists; Furosemide; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Hippocampus; Interneurons; Kinetics; Male; Neural Inhibition; Norepinephrine; Organ Culture Techniques; Organophosphorus Compounds; Patch-Clamp Techniques; Potassium; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Sympathomimetics | 2001 |
GABA mechanisms and antinociception in mice with ligated sciatic nerve.
Topics: Animals; Baclofen; Bicuculline; Dose-Response Relationship, Drug; Drug Interactions; GABA Agonists; GABA Antagonists; Ligation; Male; Mice; Mice, Inbred Strains; Morphine; Muscimol; Naloxone; Organophosphorus Compounds; Pain; Pain Measurement; Sciatic Nerve | 2001 |
Role of GABA within the nucleus tractus solitarii in the hypoxic ventilatory decline of awake rats.
Topics: Animals; Baclofen; Bicuculline; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Hypoxia; Male; Microdialysis; Microinjections; Muscimol; Neurons; Organophosphorus Compounds; Pulmonary Ventilation; Rats; Rats, Sprague-Dawley; Solitary Nucleus | 2001 |
GABA(B) receptor-mediated modulation of the firing pattern of ventral tegmental area dopamine neurons in vivo.
Topics: Action Potentials; Animals; Baclofen; Dopamine; Dose-Response Relationship, Drug; Evoked Potentials; GABA Agonists; GABA Antagonists; GABA-B Receptor Antagonists; Male; Neurons; Organophosphorus Compounds; Rats; Rats, Sprague-Dawley; Receptors, GABA-B; Ventral Tegmental Area | 2002 |
Effect of intracerebroventricular injection of GABA receptor agents on morphine-induced antinociception in the formalin test.
Topics: Analgesics, Opioid; Animals; Baclofen; Bicuculline; Dose-Response Relationship, Drug; Formaldehyde; GABA Agents; GABA Agonists; GABA Antagonists; Injections, Intraventricular; Male; Morphine; Muscimol; Organophosphorus Compounds; Pain Measurement; Rats; Receptors, GABA | 2002 |
GABA-B-related activity in processing of transcallosal response in cat motor cortex.
Topics: Animals; Baclofen; Bicuculline; Cats; Corpus Callosum; Female; GABA Agonists; GABA Antagonists; Male; Motor Cortex; Organophosphorus Compounds; Receptors, GABA-A; Receptors, GABA-B; Receptors, Presynaptic; Synaptic Transmission | 2002 |
Effects of intrahippocampal injection of GABAergic drugs on memory retention of passive avoidance learning in rats.
Topics: Animals; Avoidance Learning; Baclofen; Bicuculline; Cholinergic Agents; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Drug Interactions; GABA Agents; GABA Agonists; GABA Antagonists; Hippocampus; Male; Memory; Microinjections; Muscimol; Organophosphorus Compounds; Physostigmine; Rats; Rats, Wistar; Receptors, GABA-A; Receptors, GABA-B | 2002 |
The GABAB receptor and recognition memory: possible modulation of its behavioral effects by the nitrergic system.
Topics: Animals; Baclofen; Behavior, Animal; Discrimination, Psychological; Dose-Response Relationship, Drug; Drug Interactions; Exploratory Behavior; GABA Agonists; GABA Antagonists; Male; Memory, Short-Term; Molsidomine; Nitrergic Neurons; Organophosphorus Compounds; Psychomotor Performance; Rats; Rats, Sprague-Dawley; Receptors, GABA-B; Recognition, Psychology; Time Factors; Vasodilator Agents | 2003 |
Baclofen inhibits guinea pig magnocellular neurones via activation of an inwardly rectifying K+ conductance.
Topics: Animals; Baclofen; Electrophysiology; Female; GABA Agonists; GABA Antagonists; GABA-B Receptor Antagonists; Guinea Pigs; Immunohistochemistry; Male; Neural Inhibition; Neurons; Organophosphorus Compounds; Paraventricular Hypothalamic Nucleus; Patch-Clamp Techniques; Potassium Channels, Inwardly Rectifying; Receptors, GABA-B; RNA, Messenger; Supraoptic Nucleus | 2003 |
Hindquarters vasoconstriction through central GABA(B) receptors in conscious rats.
Topics: Animals; Baclofen; Blood Pressure; Cisterna Magna; Consciousness; Dose-Response Relationship, Drug; GABA Antagonists; GABA-B Receptor Antagonists; Hindlimb; Male; Organophosphorus Compounds; Rats; Rats, Wistar; Receptors, GABA-B; Stimulation, Chemical; Sympathetic Nervous System; Vasoconstriction | 2003 |
Inhibitory effects of spinal baclofen on spinal dorsal horn neurones in inflamed and neuropathic rats in vivo.
Topics: Animals; Baclofen; Carrageenan; Disease Models, Animal; Electric Stimulation; Electrophysiology; GABA Agonists; GABA Antagonists; GABA-B Receptor Agonists; Inflammation; Male; Organophosphorus Compounds; Posterior Horn Cells; Rats; Rats, Sprague-Dawley; Receptors, GABA-B; Spinal Cord; Spinal Nerves | 2003 |
GABA(B) receptor activation and limbic network ictogenesis.
Topics: 4-Aminopyridine; 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Animals; Baclofen; Denervation; Dose-Response Relationship, Drug; Entorhinal Cortex; Evoked Potentials; Excitatory Amino Acid Antagonists; GABA Agonists; GABA Antagonists; Hippocampus; In Vitro Techniques; Nerve Net; Neural Inhibition; Organophosphorus Compounds; Perforant Pathway; Potassium Channel Blockers; Rats; Rats, Sprague-Dawley; Receptors, GABA-B; Time Factors | 2004 |
Effect of a high-salt diet on gamma-aminobutyric acid-mediated responses in the nucleus tractus solitarius of Sprague-Dawley rats.
Topics: Animals; Baclofen; Baroreflex; Bicuculline; Blood Pressure; Cardiovascular Physiological Phenomena; Dose-Response Relationship, Drug; Food, Formulated; GABA Agonists; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; GABA-B Receptor Agonists; GABA-B Receptor Antagonists; gamma-Aminobutyric Acid; Heart Rate; Male; Muscimol; Neural Inhibition; Nipecotic Acids; Nitroprusside; Organophosphorus Compounds; Phenylephrine; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Receptors, GABA-B; Sodium Chloride, Dietary; Solitary Nucleus | 2004 |
The effects of intraperitoneal and intracerebroventricular administration of the GABAB receptor antagonist CGP 35348 on food intake in rats.
Topics: Animals; Baclofen; Drinking; Eating; GABA Agonists; GABA Antagonists; GABA-B Receptor Antagonists; Injections, Intraperitoneal; Injections, Intraventricular; Male; Organophosphorus Compounds; Rats; Rats, Wistar | 2004 |
Evidence for a selective prefrontal cortical GABA(B) receptor-mediated inhibition of glutamate release in the ventral tegmental area: a dual probe microdialysis study in the awake rat.
Topics: Animals; Baclofen; Bicuculline; Drug Interactions; GABA Agonists; GABA Antagonists; Glutamic Acid; Male; Microdialysis; Neural Inhibition; Neural Networks, Computer; Neurons; Organophosphorus Compounds; Potassium Chloride; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Ventral Tegmental Area; Wakefulness | 2005 |
Discriminative stimulus effects of gamma-hydroxybutyrate (GHB) in rats discriminating GHB from baclofen and diazepam.
Topics: 4-Butyrolactone; Anesthetics, Intravenous; Animals; Baclofen; Benzocycloheptenes; Benzylamines; Butylene Glycols; Diazepam; Discrimination, Psychological; Dithiothreitol; Dose-Response Relationship, Drug; GABA Agonists; GABA Antagonists; GABA Modulators; GABA-B Receptor Agonists; GABA-B Receptor Antagonists; Male; Organophosphorus Compounds; Phosphinic Acids; Rats; Rats, Sprague-Dawley; Sodium Oxybate | 2005 |
Gamma aminobutyric acid regulates glucosensitive neuropeptide Y neurons in arcuate nucleus via A/B receptors.
Topics: Animals; Arcuate Nucleus of Hypothalamus; Baclofen; Bicuculline; Calcium; Cells, Cultured; Dose-Response Relationship, Drug; Drug Interactions; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Glucose; Immunohistochemistry; Male; Microscopy, Immunoelectron; Muscimol; Neurons; Neuropeptide Y; Organophosphorus Compounds; Rats; Rats, Sprague-Dawley; Receptors, GABA; Time Factors | 2005 |
Effect of a selective GABA(B) receptor agonist baclofen on the mu-opioid receptor agonist-induced antinociceptive, emetic and rewarding effects.
Topics: Analgesics, Opioid; Animals; Baclofen; Conditioning, Operant; Ferrets; GABA Agonists; GABA Antagonists; GABA-B Receptor Agonists; Injections, Intraventricular; Injections, Spinal; Injections, Subcutaneous; Male; Morphine; Organophosphorus Compounds; Pain Measurement; Rats; Reaction Time; Receptors, Opioid, mu; Reward; Vomiting | 2005 |
Role of GABAB receptors in GABA and baclofen-induced inhibition of adult rat cerebellar interpositus nucleus neurons in vitro.
Topics: Action Potentials; Animals; Baclofen; Bicuculline; Calcium; Cerebellar Nuclei; Dose-Response Relationship, Drug; Drug Interactions; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Magnesium; Muscimol; Neural Inhibition; Neurons; Organophosphorus Compounds; Rats; Rats, Sprague-Dawley; Receptors, GABA-B | 2005 |
Different effects of GABAergic receptors located in the ventral tegmental area on the expression of morphine-induced conditioned place preference in rat.
Topics: Analgesics, Opioid; Animals; Baclofen; Behavior, Animal; Bicuculline; Conditioning, Operant; Dose-Response Relationship, Drug; GABA Agonists; GABA Antagonists; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; GABA-B Receptor Agonists; GABA-B Receptor Antagonists; Male; Morphine; Muscimol; Organophosphorus Compounds; Rats; Rats, Wistar; Receptors, GABA; Receptors, GABA-A; Receptors, GABA-B; Ventral Tegmental Area | 2005 |
Dopamine-mediated actions of ephedrine in the rat substantia nigra.
Topics: Action Potentials; alpha-Methyltyrosine; Animals; Baclofen; Central Nervous System Stimulants; Dopamine; Dopamine Antagonists; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Ephedrine; GABA Agonists; GABA Antagonists; Male; Organophosphorus Compounds; Rats; Rats, Sprague-Dawley; Substantia Nigra; Sulpiride | 2006 |
Pharmacologic evidence for abnormal thalamocortical functioning in GABA receptor beta3 subunit-deficient mice, a model of Angelman syndrome.
Topics: Angelman Syndrome; Animals; Anticonvulsants; Baclofen; Cerebral Cortex; Disease Models, Animal; Electrodes, Implanted; Electroencephalography; Ethosuximide; Female; GABA Agonists; GABA Antagonists; Humans; Male; Mice; Mice, Mutant Strains; Neural Pathways; Organophosphorus Compounds; Parietal Lobe; Receptors, GABA-A; Thalamus | 2005 |
Discriminative stimulus effects of flumazenil: perceptual masking by baclofen, and lack of substitution with gamma-hydroxybutyrate and its precursors 1,4-butanediol and gamma-butyrolactone.
Topics: 4-Butyrolactone; Animals; Baclofen; Benzocycloheptenes; Butylene Glycols; Columbidae; Discrimination, Psychological; Dose-Response Relationship, Drug; Flumazenil; GABA Agonists; GABA Antagonists; GABA Modulators; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; GABA-B Receptor Agonists; GABA-B Receptor Antagonists; Organophosphorus Compounds; Sodium Oxybate | 2006 |
Discriminative stimulus effects of GHB and GABA(B) agonists are differentially attenuated by CGP35348.
Topics: Analysis of Variance; Animals; Baclofen; Discrimination Learning; Discrimination, Psychological; Dose-Response Relationship, Drug; GABA Agonists; GABA Antagonists; GABA-B Receptor Agonists; GABA-B Receptor Antagonists; Male; Organophosphorus Compounds; Rats; Rats, Sprague-Dawley; Sodium Oxybate | 2006 |
Effect of GABA receptor agonists or antagonists on morphine-induced Straub tail in mice.
Topics: Analysis of Variance; Animals; Baclofen; Behavior, Animal; Bicuculline; Dose-Response Relationship, Drug; Drug Interactions; GABA Agonists; GABA Antagonists; Hindlimb Suspension; Male; Mice; Morphine; Muscimol; Narcotics; Organophosphorus Compounds; Picrotoxin | 2006 |
Inhibition of pain behavior by GABA(B) receptors in the thalamic ventrobasal complex: effect on normal rats subjected to the formalin test of nociception.
Topics: Acute Disease; Analgesics; Animals; Baclofen; Behavior, Animal; Chronic Disease; Disease Models, Animal; GABA Agonists; GABA Antagonists; GABA-B Receptor Agonists; GABA-B Receptor Antagonists; gamma-Aminobutyric Acid; Male; Neural Inhibition; Neurons; Organophosphorus Compounds; Pain; Pain Measurement; Pain Threshold; Rats; Receptors, GABA-B; Synaptic Transmission; Time Factors; Ventral Thalamic Nuclei | 2006 |
Nucleus-specific abnormalities of GABAergic synaptic transmission in a genetic model of absence seizures.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Baclofen; Epilepsy, Absence; Excitatory Postsynaptic Potentials; GABA Agonists; GABA Antagonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Immunohistochemistry; In Vitro Techniques; Intralaminar Thalamic Nuclei; Membrane Potentials; Organophosphorus Compounds; Phosphinic Acids; Propanolamines; Rats; Receptors, GABA-A; Somatosensory Cortex; Synapses; Synaptic Transmission; Ventral Thalamic Nuclei | 2006 |
Cataleptic effects of gamma-hydroxybutyrate (GHB), its precursor gamma-butyrolactone (GBL), and GABAB receptor agonists in mice: differential antagonism by the GABAB receptor antagonist CGP35348.
Topics: 4-Butyrolactone; Animals; Baclofen; Catalepsy; Dose-Response Relationship, Drug; GABA Agonists; GABA Antagonists; GABA-B Receptor Agonists; Male; Mice; Mice, Inbred C57BL; Narcolepsy; Organophosphorus Compounds; Receptors, GABA-B; Sodium Oxybate; Substance-Related Disorders | 2007 |
Understanding your inhibitions: modulation of brain cortical metabolism by GABA(B) receptors.
Topics: Animals; Baclofen; Benzylamines; Carbon Isotopes; Cerebral Cortex; GABA Agonists; GABA Antagonists; GABA-B Receptor Agonists; Guinea Pigs; Molecular Structure; Morpholines; Nuclear Magnetic Resonance, Biomolecular; Organophosphorus Compounds; Phosphinic Acids; Principal Component Analysis; Receptors, GABA-B | 2007 |
Effect of GABAergic substances on firing rate and thermal coefficient of hypothalamic neurons in the juvenile chicken.
Topics: Action Potentials; Animals; Baclofen; Bicuculline; Body Temperature Regulation; Chickens; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Hypothalamus; In Vitro Techniques; Muscimol; Neurons; Organophosphorus Compounds; Receptors, GABA-A; Receptors, GABA-B; Temperature; Time Factors | 2007 |
Differentiating the discriminative stimulus effects of gamma-hydroxybutyrate and ethanol in a three-choice drug discrimination procedure in rats.
Topics: 4-Butyrolactone; Animals; Baclofen; Benzocycloheptenes; Butylene Glycols; Discrimination, Psychological; Ethanol; Flunitrazepam; GABA Agonists; GABA Antagonists; GABA Modulators; Ketamine; Male; Organophosphorus Compounds; Rats; Rats, Sprague-Dawley; Receptors, Cell Surface; Receptors, N-Methyl-D-Aspartate; Sodium Oxybate | 2008 |
Modulation of the cough reflex by antitussive agents within the caudal aspect of the nucleus tractus solitarii in the rabbit.
Topics: Animals; Antitussive Agents; Baclofen; Cough; Dose-Response Relationship, Drug; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Male; Naloxone; Neurokinin A; Organophosphorus Compounds; Peptide Fragments; Piperidines; Rabbits; Reflex; Solitary Nucleus | 2008 |
Regulation of cardiac sympathetic afferent reflex by GABA(A) and GABA(B) receptors in paraventricular nucleus in rats.
Topics: Animals; Baclofen; Bradykinin; Capsaicin; GABA Agonists; GABA Antagonists; Heart; Isonicotinic Acids; Kidney; Male; Neurons, Afferent; Organophosphorus Compounds; Paraventricular Hypothalamic Nucleus; Pyridazines; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Receptors, GABA-B; Reflex; Sensory System Agents; Sympathetic Nervous System; Vigabatrin | 2008 |
Retrograde GABA signaling adjusts sound localization by balancing excitation and inhibition in the brainstem.
Topics: Acoustic Stimulation; Action Potentials; Anesthetics, Local; Animals; Animals, Newborn; Auditory Pathways; Baclofen; Dose-Response Relationship, Drug; Ear; Egtazic Acid; Electric Stimulation; GABA Agents; GABA Antagonists; gamma-Aminobutyric Acid; Gerbillinae; In Vitro Techniques; Lidocaine; Models, Molecular; Neural Inhibition; Neurons; Olivary Nucleus; Organophosphorus Compounds; Patch-Clamp Techniques; Receptors, GABA-B; Sound Localization; Synaptic Transmission | 2008 |
Attenuation of morphine withdrawal signs by a GABAB receptor agonist in the locus coeruleus of rats.
Topics: Analysis of Variance; Animals; Baclofen; Dose-Response Relationship, Drug; Drug Therapy, Combination; GABA Agonists; GABA Antagonists; Injections, Subcutaneous; Locus Coeruleus; Male; Morphine; Morphine Dependence; Motor Activity; Naloxone; Narcotic Antagonists; Narcotics; Organophosphorus Compounds; Rats; Rats, Wistar; Substance Withdrawal Syndrome | 2009 |
GABAB receptors within the ventral tegmental area are involved in the expression and acquisition of morphine-induced place preference in morphine-sensitized rats.
Topics: Animals; Baclofen; Conditioning, Operant; Dose-Response Relationship, Drug; Female; GABA Agonists; GABA Antagonists; Microinjections; Morphine; Motor Activity; Narcotics; Organophosphorus Compounds; Rats; Rats, Wistar; Receptors, GABA-A; Receptors, GABA-B; Reinforcement, Psychology; Ventral Tegmental Area | 2009 |
GABA(B) presynaptic receptors modulate glycine exocytosis from mouse spinal cord and hippocampus glycinergic nerve endings.
Topics: Animals; Baclofen; Benzylamines; Exocytosis; Glycine; Glycine Plasma Membrane Transport Proteins; Hippocampus; Mice; Nerve Endings; Organophosphorus Compounds; Phosphinic Acids; Receptors, GABA-B; Spinal Cord | 2009 |
Infantile spasms and Down syndrome: a new animal model.
Topics: 4-Butyrolactone; Animals; Anticonvulsants; Baclofen; Brain; Disease Models, Animal; Down Syndrome; Electroencephalography; Ethosuximide; GABA Agonists; Genotype; Humans; Infant; Mice; Mice, Mutant Strains; Organophosphorus Compounds; Phenotype; Receptors, GABA-A; Receptors, GABA-B; Spasms, Infantile; Time Factors; Valproic Acid; Vigabatrin | 2009 |
The physiological role of pre- and postsynaptic GABA(B) receptors in membrane excitability and synaptic transmission of neurons in the rat's dorsal cortex of the inferior colliculus.
Topics: Action Potentials; Animals; Baclofen; Calcium; Cell Membrane; GABA Agonists; GABA Antagonists; GABA-B Receptor Agonists; GABA-B Receptor Antagonists; In Vitro Techniques; Inferior Colliculi; Membrane Potentials; Neurons; Organophosphorus Compounds; Patch-Clamp Techniques; Potassium; Rats; Rats, Wistar; Receptors, AMPA; Receptors, GABA-B; Synapses; Synaptic Transmission | 2009 |
Pharmacological and autoradiographic studies on the pathophysiological role of GABA(B) receptors in the dystonic hamster: pronounced antidystonic effects of baclofen after striatal injections.
Topics: Animals; Animals, Genetically Modified; Autoradiography; Baclofen; Corpus Striatum; Cricetinae; Dystonia; GABA-B Receptor Agonists; GABA-B Receptor Antagonists; Microinjections; Organophosphorus Compounds; Receptors, GABA-B | 2009 |
Behavioral effects of gamma-hydroxybutyrate, its precursor gamma-butyrolactone, and GABA(B) receptor agonists: time course and differential antagonism by the GABA(B) receptor antagonist 3-aminopropyl(diethoxymethyl)phosphinic acid (CGP35348).
Topics: 4-Butyrolactone; Anesthetics, Intravenous; Animals; Baclofen; Columbidae; Conditioning, Operant; Dose-Response Relationship, Drug; GABA Agonists; GABA Antagonists; GABA-B Receptor Agonists; GABA-B Receptor Antagonists; Injections, Intramuscular; Kinetics; Organophosphorus Compounds; Sodium Oxybate | 2009 |
Angiotensin II enhances GABA(B) receptor-mediated responses and expression in nucleus tractus solitarii of rats.
Topics: Angiotensin II; Animals; Baclofen; Baroreflex; Bicuculline; Blood Pressure; Disease Models, Animal; GABA Agonists; GABA Antagonists; Hypertension; Infusion Pumps, Implantable; Male; Microinjections; Muscimol; NG-Nitroarginine Methyl Ester; Organophosphorus Compounds; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Receptors, GABA-B; Solitary Nucleus; Time Factors; Up-Regulation | 2009 |
GABAB receptor-positive modulators: enhancement of GABAB receptor agonist effects in vivo.
Topics: Animals; Baclofen; Benzofurans; Body Temperature; Dose-Response Relationship, Drug; Enzyme Inhibitors; GABA Agonists; GABA Antagonists; GABA-B Receptor Agonists; Hypothermia; Male; Mice; Mice, Inbred C57BL; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Organophosphorus Compounds; Phenols; Sodium Oxybate | 2010 |
Activation of presynaptic GABAB receptors modulates GABAergic and glutamatergic inputs to the medial geniculate body.
Topics: Aging; Animals; Baclofen; Electric Stimulation; Excitatory Postsynaptic Potentials; Female; GABA-B Receptor Agonists; GABA-B Receptor Antagonists; gamma-Aminobutyric Acid; Geniculate Bodies; Glutamic Acid; Inhibitory Postsynaptic Potentials; Male; Models, Animal; Organophosphorus Compounds; Patch-Clamp Techniques; Rats; Rats, Wistar; Receptors, GABA-B; Receptors, Presynaptic; Synaptic Transmission | 2011 |
Effects of the GABAB receptor agonist baclofen on primary drinking in rats.
Topics: Animals; Baclofen; Drinking; Food Deprivation; GABA-B Receptor Agonists; Male; Organophosphorus Compounds; Osmosis; Polyethylene Glycols; Rats; Rats, Wistar; Receptors, GABA-B; Time Factors | 2012 |
Reversal of inhibition of putative dopaminergic neurons of the ventral tegmental area: interaction of GABA(B) and D2 receptors.
Topics: Animals; Baclofen; Carbazoles; Data Collection; Dopamine; Dopamine Agonists; Dopaminergic Neurons; Enzyme Inhibitors; Extracellular Space; GABA Agonists; GABA Antagonists; In Vitro Techniques; Infusion Pumps, Implantable; Organophosphorus Compounds; Protein Kinase C; Quinpirole; Rats; Rats, Inbred F344; Receptors, Dopamine D2; Receptors, GABA-B; Ventral Tegmental Area | 2012 |
Discriminative stimulus effects of the GABAB receptor-positive modulator rac-BHFF: comparison with GABAB receptor agonists and drugs of abuse.
Topics: Animals; Baclofen; Benzodiazepines; Benzofurans; Cocaine; Columbidae; Diazepam; Discrimination, Psychological; Ethanol; GABA-B Receptor Agonists; Illicit Drugs; Nicotine; Organophosphorus Compounds; Phenols; Sodium Oxybate | 2013 |
mTORC1-dependent protein synthesis underlying rapid antidepressant effect requires GABABR signaling.
Topics: 2-Amino-5-phosphonovalerate; Animals; Baclofen; Brain-Derived Neurotrophic Factor; Calcium; Calcium Channels, L-Type; Cells, Cultured; Cytoskeletal Proteins; Excitatory Amino Acid Antagonists; GABA Antagonists; GABA-B Receptor Agonists; Hippocampus; Humans; Immobility Response, Tonic; Male; Mechanistic Target of Rapamycin Complex 1; Mice; Multiprotein Complexes; Nerve Tissue Proteins; Organophosphorus Compounds; Piperidines; Prefrontal Cortex; Primary Cell Culture; Receptors, AMPA; Receptors, GABA-B; Signal Transduction; TOR Serine-Threonine Kinases | 2013 |
Possible role of GABA-B receptor modulation in MPTP induced Parkinson's disease in rats.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Baclofen; Cerebral Cortex; Corpus Striatum; Cytokines; Disease Models, Animal; GABA-B Receptor Agonists; GABA-B Receptor Antagonists; Lipid Peroxidation; Male; Motor Activity; Organophosphorus Compounds; Oxidative Stress; Parkinsonian Disorders; Rats, Wistar; Receptors, GABA-B; Rotarod Performance Test | 2015 |
GABA acting on GABAB receptors located in a medullary pain facilitatory area enhances nociceptive behaviors evoked by intraplantar formalin injection.
Topics: Animals; Baclofen; Disease Models, Animal; Formaldehyde; GABA-B Receptor Agonists; GABA-B Receptor Antagonists; gamma-Aminobutyric Acid; Male; Medulla Oblongata; Neurons; Nociception; Nociceptors; Organophosphorus Compounds; Pain; Pain Measurement; Rats; Rats, Wistar; Receptors, GABA-B; Reticular Formation | 2015 |
GABA in Paraventricular Nucleus Regulates Adipose Afferent Reflex in Rats.
Topics: Adipose Tissue, White; Afferent Pathways; Animals; Baclofen; gamma-Aminobutyric Acid; Isonicotinic Acids; Kidney; Male; Organophosphorus Compounds; Paraventricular Hypothalamic Nucleus; Pyridazines; Rats; Rats, Sprague-Dawley; Sympathetic Nervous System; Vigabatrin | 2015 |
Influence of leptin and GABA
Topics: Action Potentials; Animals; Arcuate Nucleus of Hypothalamus; Baclofen; Chickens; Dose-Response Relationship, Drug; Female; GABA Antagonists; GABA-B Receptor Agonists; gamma-Aminobutyric Acid; In Vitro Techniques; Leptin; Male; Neurons; Organophosphorus Compounds; Patch-Clamp Techniques | 2017 |
Activation of GABA
Topics: Action Potentials; Animals; Baclofen; Cadmium Chloride; Female; GABA-B Receptor Agonists; GABA-B Receptor Antagonists; Hair Cells, Vestibular; Male; Organophosphorus Compounds; Patch-Clamp Techniques; Potassium Channels, Calcium-Activated; Presynaptic Terminals; Rats; Rats, Sprague-Dawley; Receptors, GABA-B; Semicircular Canals | 2020 |