cgp 12177 has been researched along with ici 118551 in 35 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (2.86) | 18.7374 |
| 1990's | 21 (60.00) | 18.2507 |
| 2000's | 10 (28.57) | 29.6817 |
| 2010's | 2 (5.71) | 24.3611 |
| 2020's | 1 (2.86) | 2.80 |
| Authors | Studies |
|---|---|
| Baker, JG | 1 |
| Baker, JG; Fischer, PM; Gardiner, SM; Hill, SJ; Kellam, B; Mistry, SN | 1 |
| Bronnikov, G; Houstĕk, J; Nedergaard, J | 1 |
| Leysen, JE; Pauwels, PJ; Van Gompel, P | 1 |
| Dunn, AJ; Yang, XM | 1 |
| Cheetham, SC; Crompton, MR; De Paermentier, F; Horton, RW | 1 |
| Ali-Melkkilä, T; Iisalo, E; Kaila, T; Saari, KM; Vuori, ML | 2 |
| Iisalo, E; Kaila, T; Saari, KM; Vuori, ML | 1 |
| Sanghani, MP; Scarpace, PJ | 1 |
| Cowburn, RF; Fowler, CJ; O'Neill, C; Ravid, R; Vestling, M; Winblad, B | 1 |
| Adachi-Akahane, S; Kitagawa, Y; Nagao, T | 1 |
| Cannon, B; Dicker, A; Nedergaard, J | 1 |
| Batink, HD; Boer, GJ; Doornbos, T; Dubois, EA; Janssen, AG; Pfaffendorf, M; Somsen, GA; van den Bos, JC; van Doremalen, PA; van Royen, EA; van Zwieten, PA; Vekemans, JA | 1 |
| Arner, P; Blaak, EE; Gafvels, ME; Lonnqvist, F; Shimizu, M | 1 |
| Chen, CM; Ko, FN; Lin, CH; Teng, CM; Yang, CM | 1 |
| Morin, D; Onteniente, B; Sapena, R; Tillement, JP; Zini, R | 1 |
| Germack, R; Perret, GY; Starzec, AB; Vassy, R | 1 |
| Atlan, G; Collet, F; Féve, B; Frisdal, E; Pavoine, C; Pecker, F | 1 |
| Fernández-López, A; Revilla, R; Revilla, V | 1 |
| Ajisawa, Y; Akahane, M; Andersson, KE; Hayakawa, K; Igawa, Y; Nishizawa, O; Takeda, H; Yamazaki, Y; Yoneyama, T | 1 |
| Farias-Silva, E; Grassi-Kassisse, DM; Spadari-Bratfisch, RC; Wolf-Nunes, V | 1 |
| Badino, P; Bergamasco, L; Borgarelli, M; Girardi, C; Odore, R; Re, G; Tarducci, A; Zanatta, R | 1 |
| Agarwal, D; Glasel, JA | 1 |
| Giacobino, JP; Jimenez, M; Kaumann, AJ; Moffatt, J; Molenaar, P; Oostendorp, J; Preitner, F | 1 |
| Aureggi, G; Croci, T; Ferla, G; Guagnini, F; Le Fur, G; Maffrand, JP; Manara, L; Mukenge, S | 1 |
| Busch, M; Funsch, B; Gradl, G; Lohse, MJ; Pschorr, J; Scheel, AA | 1 |
| Katynski, AL; Kennedy, SW; Moon, TW; Vijayan, MM | 1 |
| Brahmadevara, N; MacDonald, A; Shaw, AM | 1 |
| Caceres, VM; Krieger, MH; Moreira, MF; Santos, IN; Spadari-Bratfisch, RC; Sumitame, M | 1 |
| Carter, AA; Hill, SJ | 1 |
| Badino, P; Barbero, R; Cuniberti, B; Girardi, C; Magistris, G; Odore, R; Pagliasso, S; Re, G | 1 |
| Baranowska, U; Godlewski, G; Malinowska, B; Schlicker, E | 1 |
| Abraham, G; Guenl, B; Jonas, S; Kassahun, WT; Ungemach, FR | 1 |
| Iiboshi, Y; Kasuya, Y; Obara, K; Shigematsu, M; Takahasi, H; Tanaka, Y; Yoshioka, K | 1 |
3 trial(s) available for cgp 12177 and ici 118551
| Article | Year |
|---|---|
Absorption of ocular timolol: drug concentrations and beta-receptor binding activity in the aqueous humour of the treated and contralateral eye.
Topics: Absorption; Administration, Topical; Adrenergic beta-Antagonists; Aged; Animals; Aqueous Humor; Cataract Extraction; Heart Rate; Humans; Lenses, Intraocular; Ophthalmic Solutions; Propanolamines; Rabbits; Radioligand Assay; Rats; Receptors, Adrenergic, beta; Timolol | 1993 |
Concentrations and antagonist activity of topically applied betaxolol in aqueous humour.
Topics: Absorption; Administration, Topical; Adrenergic beta-Antagonists; Aged; Aged, 80 and over; Aqueous Humor; Betaxolol; Cataract Extraction; Humans; Lenses, Intraocular; Ophthalmic Solutions; Propanolamines; Radioligand Assay; Receptors, Adrenergic, beta | 1993 |
Beta 1- and beta 2-antagonist activity of topically applied betaxolol and timolol in the systemic circulation.
Topics: Administration, Topical; Adrenergic beta-1 Receptor Antagonists; Adrenergic beta-2 Receptor Antagonists; Adrenergic beta-Antagonists; Aged; Aged, 80 and over; Betaxolol; Humans; Middle Aged; Propanolamines; Radioligand Assay; Receptors, Adrenergic, beta-1; Receptors, Adrenergic, beta-2; Timolol | 1993 |
32 other study(ies) available for cgp 12177 and ici 118551
| Article | Year |
|---|---|
The selectivity of beta-adrenoceptor antagonists at the human beta1, beta2 and beta3 adrenoceptors.
Topics: Adrenergic beta-1 Receptor Agonists; Adrenergic beta-2 Receptor Agonists; Adrenergic beta-3 Receptor Agonists; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Algorithms; Animals; Cell Line; CHO Cells; Cricetinae; Dioxoles; Humans; Propanolamines; Receptors, Adrenergic, beta-1; Receptors, Adrenergic, beta-2; Receptors, Adrenergic, beta-3 | 2005 |
Synthesis and in vitro and in vivo characterization of highly β1-selective β-adrenoceptor partial agonists.
Topics: Adrenergic beta-1 Receptor Agonists; Animals; Binding, Competitive; CHO Cells; Cricetinae; Cricetulus; Cyclic AMP; Drug Design; Heart Rate; Hemodynamics; Humans; Indicators and Reagents; Ligands; Male; Propanolamines; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta-1; Structure-Activity Relationship | 2013 |
Beta-adrenergic, cAMP-mediated stimulation of proliferation of brown fat cells in primary culture. Mediation via beta 1 but not via beta 3 adrenoceptors.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adipose Tissue, Brown; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Bucladesine; Cell Division; Cells, Cultured; Cholera Toxin; Colforsin; Cyclic AMP; DNA Replication; Imidazoles; Mice; Mice, Inbred Strains; Norepinephrine; Oxymetazoline; Propanolamines; Receptors, Adrenergic, beta; Thymidine | 1992 |
Human beta 1- and beta 2-adrenergic receptor binding and mediated accumulation of cAMP in transfected Chinese hamster ovary cells. Profile of nebivolol and known beta-adrenergic blockers.
Topics: Adrenergic beta-Antagonists; Animals; Benzopyrans; Binding Sites; Binding, Competitive; Cell Line; Cricetinae; Cricetulus; Cyclic AMP; Ethanolamines; Humans; Imidazoles; Isoproterenol; Models, Biological; Nebivolol; Propanolamines; Propranolol; Radioligand Assay; Receptors, Adrenergic, beta; Stereoisomerism; Transfection | 1991 |
Central beta 1-adrenergic receptors are involved in CRF-induced defensive withdrawal.
Topics: Animals; Atenolol; Behavior, Animal; Corticotropin-Releasing Hormone; Injections, Intraperitoneal; Injections, Intraventricular; Male; Propanolamines; Propranolol; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta | 1990 |
Beta-adrenoceptors in human brain labelled with [3H]dihydroalprenolol and [3H]CGP 12177.
Topics: Adrenergic beta-Antagonists; Alprenolol; Binding, Competitive; Brain Chemistry; Dihydroalprenolol; Humans; Imidazoles; In Vitro Techniques; Isoproterenol; Kinetics; Male; Membranes; Middle Aged; Practolol; Propanolamines; Propranolol; Receptors, Adrenergic, beta | 1989 |
Atypical beta-adrenergic receptors in rat liver: evidence for transient expression during aging.
Topics: Adenylyl Cyclases; Adrenergic beta-Antagonists; Aging; Animals; Isoproterenol; Liver; Male; Propanolamines; Rats; Rats, Inbred F344; Receptors, Adrenergic, beta | 1994 |
Disrupted beta 1-adrenoceptor-G protein coupling in the temporal cortex of patients with Alzheimer's disease.
Topics: Aged; Alzheimer Disease; Binding, Competitive; Female; GTP-Binding Proteins; Guanylyl Imidodiphosphate; Humans; Isoproterenol; Male; Middle Aged; Propanolamines; Protein Binding; Receptors, Adrenergic, beta; Signal Transduction; Synaptic Membranes; Temporal Lobe | 1993 |
Determination of beta-adrenoceptor subtype on rat isolated ventricular myocytes by use of highly selective beta-antagonists.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Binding, Competitive; Cyclic AMP; Heart Ventricles; Imidazoles; Iodocyanopindolol; Isoproterenol; Kinetics; Male; Membranes; Myocardium; Pindolol; Propanolamines; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta-1; Receptors, Adrenergic, beta-2; Stimulation, Chemical; Tritium | 1995 |
Stimulation of nonshivering thermogenesis in the Syrian hamster by norepinephrine and beta-selective adrenergic agents: a phenomenon of refractoriness.
Topics: Acclimatization; Adipose Tissue, Brown; Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Body Temperature Regulation; Cold Temperature; Cricetinae; Drug Interactions; Ethanolamines; Female; Isoproterenol; Male; Mesocricetus; Norepinephrine; Oxygen Consumption; Phenoxyacetates; Phenoxypropanolamines; Propanolamines; Reproducibility of Results; Shivering | 1996 |
Synthesis and in vitro and in vivo characteristics of an iodinated analogue of the beta-adrenoceptor antagonist carazolol.
Topics: Adrenergic beta-Antagonists; Animals; Brain; Carbazoles; Cell Membrane; Heart Ventricles; Indicators and Reagents; Iodine Radioisotopes; Lung; Magnetic Resonance Spectroscopy; Male; Myocardium; Propanolamines; Rabbits; Radioligand Assay; Receptors, Adrenergic, beta; Tissue Distribution | 1996 |
Agonist and antagonist properties of beta 3-adrenoceptors in human omental and mouse 3T3-L1 adipocytes.
Topics: Adipose Tissue; Adrenergic alpha-Antagonists; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Humans; Isoproterenol; Lipolysis; Mice; Omentum; Propanolamines; Receptors, Adrenergic, beta; Receptors, Adrenergic, beta-3; Yohimbine | 1996 |
Pharmacological characteristics of BDTI, a new isoquinoline-derived beta 2-adrenoceptor agonist, in canine trachea and rat heart.
Topics: Adrenergic beta-2 Receptor Agonists; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Albuterol; Animals; Atenolol; Carbachol; Cells, Cultured; Dogs; Dose-Response Relationship, Drug; Female; Heart; Isoproterenol; Male; Muscle Contraction; Muscle, Smooth; Myocardial Contraction; Myocardium; Propanolamines; Radioligand Assay; Rats; Rats, Wistar; Trachea; Tretoquinol | 1996 |
Characterization of beta-adrenergic receptors of freshly isolated astrocytes and neurons from rat brain.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Astrocytes; Binding, Competitive; Cells, Cultured; Cerebellum; Imidazoles; Immunohistochemistry; Male; Neurons; Propanolamines; Prosencephalon; Rats; Rats, Wistar; Receptors, Adrenergic, beta | 1997 |
Beta-adrenoceptor subtype expression and function in rat white adipocytes.
Topics: Adipocytes; Adrenergic beta-Agonists; Animals; Binding, Competitive; Imidazoles; Lipolysis; Male; Propanolamines; Rats; Rats, Wistar; Receptors, Adrenergic, beta | 1997 |
Pharmacological and molecular characterisation of beta-adrenoceptors in adult rat diaphragm muscle.
Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Aging; Animals; Dose-Response Relationship, Drug; Fenoterol; Imidazoles; Isoproterenol; Male; Muscle, Smooth; Pindolol; Prenalterol; Propanolamines; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta; Receptors, Adrenergic, beta-1; Receptors, Adrenergic, beta-2; Receptors, Adrenergic, beta-3 | 1998 |
A comparative study of the beta-adrenoceptors in higher visual centres of birds.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Autoradiography; Birds; Male; Propanolamines; Receptors, Adrenergic, beta; Tritium; Visual Pathways | 1998 |
Functional and molecular biological evidence for a possible beta3-adrenoceptor in the human detrusor muscle.
Topics: Adrenergic alpha-Agonists; Adrenergic beta-1 Receptor Agonists; Adrenergic beta-1 Receptor Antagonists; Adrenergic beta-2 Receptor Agonists; Adrenergic beta-2 Receptor Antagonists; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Colforsin; Dioxoles; Dobutamine; Dose-Response Relationship, Drug; Epinephrine; Ethanolamines; Female; Gene Expression; Humans; Imidazoles; In Vitro Techniques; Isoproterenol; Male; Middle Aged; Muscle Relaxation; Muscle, Smooth; Norepinephrine; Propanolamines; Receptors, Adrenergic, beta; Receptors, Adrenergic, beta-3; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 1999 |
Stress-induced alteration in the lipolytic response to beta-adrenoceptor agonists in rat white adipocytes.
Topics: Adipose Tissue; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Albuterol; Animals; Body Weight; Bucladesine; Eating; Epinephrine; Ethanolamines; Glycerol; Isoproterenol; Lipolysis; Male; Metoprolol; Norepinephrine; Propanolamines; Rats; Rats, Wistar; Stress, Physiological | 1999 |
Canine dilated cardiomyopathy: lymphocyte and cardiac alpha(1)- and beta-adrenoceptor concentrations in normal and affected great danes.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Cardiomyopathy, Dilated; Catecholamines; Dog Diseases; Dogs; Electrocardiography; Female; Heart Failure; Lymphocyte Count; Lymphocytes; Male; Myocardium; Prazosin; Propanolamines; Receptors, Adrenergic; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, beta-1; Receptors, Adrenergic, beta-2 | 1999 |
Differential effects of opioid and adrenergic agonists on proliferation in a cultured cell line.
Topics: 3T3 Cells; Adrenergic beta-2 Receptor Agonists; Adrenergic beta-Agonists; Analgesics, Opioid; Animals; Cell Culture Techniques; Cell Division; Cloning, Molecular; Colforsin; Cyclic AMP; Gene Expression Regulation, Enzymologic; Hypoglycemic Agents; Insulin; JNK Mitogen-Activated Protein Kinases; MAP Kinase Kinase 4; MAP Kinase Signaling System; Mice; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Morphine; Procaterol; Propanolamines; Radioligand Assay; Receptors, Adrenergic, beta-2; Receptors, Opioid, delta; RNA, Messenger; Second Messenger Systems; Transfection; Tritium | 1999 |
Contribution of beta-adrenoceptor subtypes to relaxation of colon and oesophagus and pacemaker activity of ureter in wildtype and beta(3)-adrenoceptor knockout mice.
Topics: Adrenergic beta-1 Receptor Antagonists; Adrenergic beta-2 Receptor Antagonists; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Colon; Dioxoles; Dose-Response Relationship, Drug; Epinephrine; Esophagus; Female; Imidazoles; In Vitro Techniques; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Inbred Strains; Mice, Knockout; Muscle Relaxation; Norepinephrine; Propanolamines; Receptors, Adrenergic, beta; Receptors, Adrenergic, beta-1; Receptors, Adrenergic, beta-2; Receptors, Adrenergic, beta-3; RNA, Messenger; Ureter | 2000 |
Functional assessment of beta adrenoceptor subtypes in human colonic circular and longitudinal (taenia coli) smooth muscle.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Aged; Colon; Female; Humans; Imidazoles; Isoproterenol; Male; Middle Aged; Muscle Relaxation; Muscle, Smooth; Propanolamines; Propranolol; Receptors, Adrenergic, beta; Terbutaline; Tetrahydronaphthalenes | 2000 |
Receptor-ligand interactions studied with homogeneous fluorescence-based assays suitable for miniaturized screening.
Topics: Betacellulin; Cell Line; Drug Evaluation, Preclinical; Epidermal Growth Factor; ErbB Receptors; Fluorescence; Fluorescent Dyes; Growth Substances; Humans; Intercellular Signaling Peptides and Proteins; Ligands; Miniaturization; Optics and Photonics; Propanolamines; Propranolol; Receptors, Adrenergic, beta-2; Receptors, Cell Surface; Recombinant Proteins; Sensitivity and Specificity | 2001 |
3,3',4,4',5-Pentachlorobiphenyl (PCB 126) impacts hepatic lipid peroxidation, membrane fluidity and beta-adrenoceptor kinetics in chick embryos.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Binding Sites; Binding, Competitive; Cell Membrane; Chick Embryo; Cytochrome P-450 CYP1A1; Epinephrine; Fluorescence Polarization; Kinetics; Lipid Peroxidation; Liver; Membrane Fluidity; Microsomes, Liver; Ovum; Polychlorinated Biphenyls; Procaterol; Propanolamines; Receptors, Adrenergic, beta | 2004 |
ALpha1-adrenoceptor antagonist properties of CGP 12177A and other beta-adrenoceptor ligands: evidence against beta(3)- or atypical beta-adrenoceptors in rat aorta.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adrenergic alpha-1 Receptor Antagonists; Adrenergic beta-Antagonists; Alprenolol; Animals; Aorta, Thoracic; Binding Sites; Bupranolol; Cell Membrane; Cerebral Cortex; Dose-Response Relationship, Drug; Ethanolamines; Imidazoles; Male; Muscle, Smooth, Vascular; Phenylephrine; Pindolol; Prazosin; Propanolamines; Propranolol; Radioligand Assay; Rats; Rats, Wistar; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, beta-3; Tritium; United Kingdom; Vasoconstriction | 2004 |
Evidence for two atypical conformations of beta-adrenoceptors and their interaction with Gi proteins.
Topics: Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Dose-Response Relationship, Drug; GTP-Binding Protein alpha Subunits, Gi-Go; Heart; Heart Atria; Imidazoles; In Vitro Techniques; Isoproterenol; Male; Myocardial Contraction; Norepinephrine; Pertussis Toxin; Propanolamines; Protein Binding; Protein Conformation; Rats; Rats, Wistar; Receptors, Adrenergic, beta; Receptors, Adrenergic, beta-1 | 2005 |
Characterization of isoprenaline- and salmeterol-stimulated interactions between beta2-adrenoceptors and beta-arrestin 2 using beta-galactosidase complementation in C2C12 cells.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Albuterol; Animals; Arrestins; beta-Arrestin 2; beta-Arrestins; beta-Galactosidase; Cell Line; CHO Cells; Colforsin; Cricetinae; Cyclic AMP; Genetic Complementation Test; Humans; Isoproterenol; Mutation; Propanolamines; Propranolol; Receptors, Adrenergic, beta-2; Recombinant Fusion Proteins; Salmeterol Xinafoate; Transfection | 2005 |
Effects of Inflammation upon beta-adrenoceptor concentrations in the common digital artery of the horse: an in vitro study.
Topics: Adrenergic beta-Antagonists; Animals; Arteries; Horse Diseases; Horses; Imidazoles; In Vitro Techniques; Lipopolysaccharides; Muscle, Smooth, Vascular; Propanolamines; Receptors, Adrenergic, beta-1; Receptors, Adrenergic, beta-2; Vasculitis | 2005 |
Recruitment of functionally active heart beta2-adrenoceptors in the initial phase of endotoxic shock in pithed rats.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Cardiovascular Physiological Phenomena; Fenoterol; Heart Rate; Isoproterenol; Lipopolysaccharides; Male; Myocardium; Prenalterol; Propanolamines; Rats; Rats, Wistar; Receptors, Adrenergic, beta-2; Shock, Septic; Tachycardia | 2006 |
Expression and functional coupling of liver β2 - adrenoceptors in the human hepatocellular carcinoma.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Adult; Aged; Carcinoma, Hepatocellular; Female; Humans; Imidazoles; Iodocyanopindolol; Liver; Liver Neoplasms; Male; Middle Aged; Propanolamines; Receptors, Adrenergic, beta-2 | 2012 |
Pharmacological properties of β-adrenoceptors mediating rat superior mesenteric artery relaxation and the effects of chemical sympathetic denervation.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Isoproterenol; Male; Mesenteric Artery, Superior; Muscle Relaxation; Propanolamines; Rats; Rats, Wistar; Receptors, Adrenergic, beta; Sympathectomy, Chemical | 2020 |