Compounds > cgp 12177

cgp 12177 and 1-methyl-3-isobutylxanthine

cgp 12177 has been researched along with 1-methyl-3-isobutylxanthine in 11 studies

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19901 (9.09)18.7374
1990's6 (54.55)18.2507
2000's3 (27.27)29.6817
2010's1 (9.09)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bouscarel, B; Cortinovis, C; Mayer, D; Murat, JC; Paris, H1
Langer, L; Lemmer, B; Olbrich, HG; Witte, K1
Kaumann, AJ; Lynham, JA1
Baamonde, C; Dierssen, M; Flórez, J; García-Calatayud, S; Lumbreras, MA; Vallina, IF1
Nürnberger, F; Pleschka, K1
Brown, D; Freestone, NS; Heubach, JF; Kaumann, AJ; Ravens, U; Wettwer, E1
Freestone, NS; Kaumann, AJ; Molenaar, P; Sarsero, D1
Engelhardt, S; Hein, L; Kaumann, AJ; Lohse, M; Molenaar, P1
Han, S; Kim, JS; Kim, KT; Namgung, U; Suh, BC1
Colledge, WH; Grace, AA; Joseph, SS; Kaumann, AJ; Lynham, JA; Molenaar, P1
Abdelkrim, MA; Chatagnon, G; Desfontis, JC; Gogny, M; Mallem, MY; Noireaud, J1

Other Studies

11 other study(ies) available for cgp 12177 and 1-methyl-3-isobutylxanthine

ArticleYear
Study of beta-adrenoceptors and beta-adrenergic responsiveness in cultured "preneoplastic-like" and neoplastic rat hepatocytes.
    General pharmacology, 1985, Volume: 16, Issue:3

    Topics: 1-Methyl-3-isobutylxanthine; Adrenergic beta-Antagonists; Albuterol; Animals; Atenolol; Binding, Competitive; Cells, Cultured; Cyclic AMP; Epinephrine; Isoproterenol; Kinetics; Liver Neoplasms, Experimental; Norepinephrine; Precancerous Conditions; Propanolamines; Propranolol; Rats; Receptors, Adrenergic, beta

1985
Uncoupling of beta 1-adrenoceptors from cardiac adenylyl cyclase in cardiomyopathic and control hamsters.
    European journal of pharmacology, 1993, Oct-15, Volume: 247, Issue:2

    Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Adrenergic beta-Antagonists; Animals; Binding, Competitive; Cardiomyopathies; Cricetinae; Heart Ventricles; Imidazoles; Isoproterenol; Male; Membranes; Mesocricetus; Myocardium; Propanolamines; Radioligand Assay; Rats; Rats, Wistar; Receptors, Adrenergic, beta-1

1993
Stimulation of cyclic AMP-dependent protein kinase in rat atria by (-)-CGP 12177 through an atypical beta-adrenoceptor.
    British journal of pharmacology, 1997, Volume: 120, Issue:7

    Topics: 1-Methyl-3-isobutylxanthine; Animals; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Heart Atria; Propanolamines; Rats; Rats, Wistar; Receptors, Adrenergic, beta

1997
Alterations of central noradrenergic transmission in Ts65Dn mouse, a model for Down syndrome.
    Brain research, 1997, Feb-28, Volume: 749, Issue:2

    Topics: 1-Methyl-3-isobutylxanthine; Adrenergic beta-Agonists; Animals; Brain; Cell Membrane; Cerebellum; Cerebral Cortex; Chromosome Mapping; Chromosomes, Human, Pair 21; Colforsin; Cyclic AMP; Down Syndrome; Hippocampus; Humans; In Vitro Techniques; Isoproterenol; Kinetics; Mice; Mice, Neurologic Mutants; Norepinephrine; Organ Specificity; Propanolamines; Receptors, Adrenergic, beta; Reference Values; Signal Transduction

1997
Beta-adrenergic signal transduction in the hypothalamus of the European hamster: relation with the seasonal hibernation cycle and the diurnal activity cycle.
    Biology of the cell, 1997, Volume: 89, Issue:8

    Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Arousal; Chlorides; Circadian Rhythm; Colforsin; Cricetinae; Cyclic AMP; Enzyme Activation; Guanylyl Imidodiphosphate; Hibernation; Hypothalamus; Imidazoles; Light; Male; Manganese Compounds; Propanolamines; Receptors, Adrenergic, beta-1; Receptors, Adrenergic, beta-2; Seasons; Signal Transduction

1997
Beta4-adrenoceptors are more effective than beta1-adrenoceptors in mediating arrhythmic Ca2+ transients in mouse ventricular myocytes.
    Naunyn-Schmiedeberg's archives of pharmacology, 1999, Volume: 360, Issue:4

    Topics: 1-Methyl-3-isobutylxanthine; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Arrhythmias, Cardiac; Calcium; Dose-Response Relationship, Drug; Drug Interactions; Electric Stimulation; Heart Ventricles; In Vitro Techniques; Isoproterenol; Male; Mice; Patch-Clamp Techniques; Phosphodiesterase Inhibitors; Propanolamines; Propranolol; Receptors, Adrenergic, beta; Receptors, Adrenergic, beta-1; Time Factors

1999
Putative beta 4-adrenoceptors in rat ventricle mediate increases in contractile force and cell Ca2+: comparison with atrial receptors and relationship to (-)-[3H]-CGP 12177 binding.
    British journal of pharmacology, 1999, Volume: 128, Issue:7

    Topics: 1-Methyl-3-isobutylxanthine; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Arrhythmias, Cardiac; Calcium; Cardiotonic Agents; Female; Heart Atria; Heart Ventricles; In Vitro Techniques; Kinetics; Male; Myocardial Contraction; Norepinephrine; Papillary Muscles; Propanolamines; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta; Tritium

1999
Abolition of (-)-CGP 12177-evoked cardiostimulation in double beta1/beta2-adrenoceptor knockout mice. Obligatory role of beta1-adrenoceptors for putative beta4-adrenoceptor pharmacology.
    Naunyn-Schmiedeberg's archives of pharmacology, 2001, Volume: 363, Issue:1

    Topics: 1-Methyl-3-isobutylxanthine; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Atrial Function; Binding, Competitive; Bucladesine; Dose-Response Relationship, Drug; Female; Genotype; Heart Atria; In Vitro Techniques; Isoproterenol; Male; Membranes; Mice; Mice, Knockout; Myocardial Contraction; Pindolol; Propanolamines; Receptors, Adrenergic, beta; Receptors, Adrenergic, beta-1; Receptors, Adrenergic, beta-2; Sinoatrial Node; Tritium

2001
Selective inhibition of beta(2)-adrenergic receptor-mediated cAMP generation by activation of the P2Y(2) receptor in mouse pineal gland tumor cells.
    Journal of neurochemistry, 2001, Volume: 77, Issue:6

    Topics: 1-Methyl-3-isobutylxanthine; Adenosine Diphosphate; Adenosine Triphosphate; Adenylyl Cyclases; Adrenergic beta-Agonists; Animals; Bombesin; Calcium; Cyclic AMP; Extracellular Space; Isoproterenol; Mice; Pertussis Toxin; Phosphodiesterase Inhibitors; Pinealoma; Propanolamines; Receptors, Adrenergic, beta-2; Receptors, Purinergic P2; Receptors, Purinergic P2Y2; Signal Transduction; Thionucleotides; Tritium; Tumor Cells, Cultured; Uridine Triphosphate; Virulence Factors, Bordetella

2001
Intrinsic sympathomimetic activity of (-)-pindolol mediated through a (-)-propranolol-resistant site of the beta1-adrenoceptor in human atrium and recombinant receptors.
    Naunyn-Schmiedeberg's archives of pharmacology, 2003, Volume: 368, Issue:6

    Topics: 1-Methyl-3-isobutylxanthine; Adrenergic beta-1 Receptor Antagonists; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Aged; Animals; Binding Sites; CHO Cells; Cricetinae; Cyclic AMP; Drug Interactions; Drug Resistance; Female; Heart; Heart Atria; Humans; In Vitro Techniques; Isoproterenol; Male; Middle Aged; Myocardial Contraction; Norepinephrine; omega-N-Methylarginine; Pindolol; Propanolamines; Propranolol; Receptors, Adrenergic, beta-1; Recombinant Proteins; Stereoisomerism; Sympathomimetics

2003
Autoantibodies against cardiac β(1)-adrenoceptor do not affect the low-affinity state β(1)-adrenoceptor-mediated inotropy in rat cardiomyocytes.
    Canadian journal of physiology and pharmacology, 2012, Volume: 90, Issue:4

    Topics: 1-Methyl-3-isobutylxanthine; Adrenergic beta-1 Receptor Agonists; Adrenergic beta-1 Receptor Antagonists; Animals; Autoantibodies; Bisoprolol; Isoproterenol; Male; Myocardial Contraction; Myocytes, Cardiac; Phosphodiesterase Inhibitors; Pindolol; Propanolamines; Propranolol; Rats; Rats, Wistar; Receptors, Adrenergic, beta-1

2012