cetraxate and tranexamic acid

cetraxate has been researched along with tranexamic acid in 61 studies

Research

Studies (61)

TimeframeStudies, this research(%)All Research%
pre-199030 (49.18)18.7374
1990's17 (27.87)18.2507
2000's14 (22.95)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ito, M; Sudo, Y; Suzuki, Y1
Ito, S; Kambara, T; Kishi, S; Murakami, T1
Aibara, S; Hashizume, T; Hirokawa, K; Kasahara, A; Nishida, A; Ogawa, H1
Fusamoto, H; Hayashi, N; Kamada, T; Kawano, S; Tsuji, S1
Alexiou, A; Archimandritis, A; Bougas, S; Fertakis, A; Tjivras, M1
Honda, K; Kamato, T; Miyata, K; Nishida, A1
Ardizzone, S; Bianchi Porro, G; Petrillo, M1
Goto, H; Kuroiwa, M; Nakazawa, S; Ozawa, T; Sugiyama, S; Tsukamoto, Y1
Magaribuchi, T; Onoda, Y; Takido, M; Tamaki, H1
Ikarashi, Y; Kawano, O; Kobayashi, M; Misaki, N; Nishimura, N; Uchida, M1
Imura, A; Kuroda, H; Miyadera, A; Suzuki, A1
Lee, YC; Ng, NS; Tam, HC; Wong, HY1
Imura, A; Kaneuchi, T; Kuroda, H; Miyadera, A1
Maeda, T1
Ikeda, T; Kurebayashi, Y; Osada, Y1
Fukuchi, S1
Sakai, M1
Ishimori, A; Kawamura, T1
Fukutomi, H; Shimakura, S1
Miyake, T1
Iishi, H; Taniguchi, H; Tatsuta, M; Yamamura, H1
Hamada, K; Okada, Y; Sekiguchi, H; Taga, F1
Gomita, Y; Ichimaru, Y1
Hirohara, J; Okumura, T; Saito, K; Sameshima, Y; Sugatani, J1
Aihara, H; Arai, I; Hirose, H; Isobe, Y; Murakami, S; Muramatsu, M; Usuki, C1
Hoshina, K; Naruchi, T; Takeshita, T; Yamazaki, N1
Israsena, S; Kladchareon, N; Kositsurunkakul, S; Wilairatana, S1
Naito, S; Tanaka, H1
Maki, M; Sasaki, K1
Miura, K; Yamagata, S1
Aratani, S; Enomoto, H; Kimura, K; Mimura, K; Nomura, A; Ueda, F2
Sumi, H; Toki, N1
Chen, RR; Sung, JL; Wang, CY; Wang, TH; Yu, JY1
Azuumi, Y; Hotta, K; Ishihara, K; Ohara, S; Okabe, H1
Azuumi, Y; Hotta, K; Ishihara, K; Kakei, M; Ohara, S; Okabe, H1
Itoh, M; Matsuo, Y1
Ishizuka, Y; Kamisaki, T; Kawashima, M; Matsuda, M; Sato, M; Shimazaki, I; Terashima, K; Yaginuma, H1
Fukutomi, H; Goto, K; Kashimura, H; Lazaratos, S; Miyauchi, T; Nakahara, A; Osuga, T1
Ikeda, T; Kakegawa, H; Matsumoto, H; Miyataka, H; Satoh, T; Ueda, H1
Ikeda, T; Kakegawa, H; Matsumoto, H; Miyataka, H; Momoi, Y; Satoh, T; Ueda, H1
Fukumura, D; Kurose, I; Miura, S; Nagata, H; Oshio, C; Sekizuka, E; Suematsu, M; Tsuchiya, M1
Goto, H; Hayakawa, T; Sugiyama, S; Tachi, K1
Ishizuka, Y; Kamisaki, T; Kawashima, M; Okamoto, H; Sato, M1
Kawahara, T; Kihara, Y; Maga, T; Mikami, Y; Mizuno, M; Okada, H; Tanaka, S; Tsuji, T; Yoshinaga, F; Yunoki, N1
Ikarashi, Y; Ishige, A; Kase, Y; Maruyama, Y; Torimaru, Y; Yuzurihara, M1
Haruma, K; Hattori, N; Kajiyama, G; Kamada, T; Kawamura, Y; Kitadai, Y; Mihara, M; Miyoshi, E; Mukai, T; Sumii, K; Tahara, K; Yoshihara, M1
Honda, K; Kataoka, M; Kita, S; Ono, H; Sakamoto, K; Shimizu, S1
Adachi, K; Fujishiro, H; Ishihara, S; Kawamura, A; Kazumori, H; Kinoshita, Y; Moriyama, N; Okuyama, T; Sato, H; Suetsugu, H; Watanabe, M1
Honda, K; Kataoka, M; Shimizu, S1
Honda, K; Kataoka, M; Kita, S; Sakamoto, K; Shimizu, S1
KUNDRATITZ, K1
Itoh, H; Katagiri, F; Sato, Y; Takeyama, M1
Chen, A; Chen, JL; Hsu, PI; Jou, HS; Lai, KH; Lin, CK; Lo, CC; Lo, GH; Peng, NJ; Shie, CB; Tsai, PM; Tseng, HH; Wu, CJ1
Ahn, BO; Choi, MG; Kim, MH; Ryu, JS; Seol, SY; Shin, DW1
Hiki, N; Imamura, K; Kaminishi, M; Kubota, K; MaFune, K; Nozaki, K; Shimizu, N; Shimoyama, S; Takeshita, Y; Ueda, T; Yamaguchi, H1
Inoue, S; Itoh, H; Katagiri, F; Sato, Y; Shiga, T; Takeyama, M1
Fujishiro, M; Ichinose, M; Oka, M; Omata, M1
Kaminishi, M; Kubota, K; Shimizu, N1
Arakawa, T; Fujiwara, Y; Higuchi, K; Oshitani, N; Shiba, M; Tanigawa, T; Tominaga, K; Watanabe, T1
Arakawa, T; Sugimori, S; Watanabe, T1

Reviews

2 review(s) available for cetraxate and tranexamic acid

ArticleYear
[Eradication therapy for the remnant stomach infected with Helicobacter pylori ].
    Nihon rinsho. Japanese journal of clinical medicine, 2005, Volume: 63 Suppl 11

    Topics: Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer Agents; Clarithromycin; Drug Therapy, Combination; Enzyme Inhibitors; Gastric Stump; Helicobacter Infections; Helicobacter pylori; Humans; Omeprazole; Proton Pump Inhibitors; Stomach Neoplasms; Tranexamic Acid

2005
[Side effects of gastric muco-protective agents].
    Nihon rinsho. Japanese journal of clinical medicine, 2007, Oct-28, Volume: 65 Suppl 8

    Topics: Adjuvants, Pharmaceutic; Alanine; Alprostadil; Aluminum; Anti-Ulcer Agents; Diterpenes; Drug Interactions; Gastric Acid; Gastric Emptying; Humans; Hydrogen-Ion Concentration; Misoprostol; Quinolones; Sulpiride; Tranexamic Acid

2007

Trials

14 trial(s) available for cetraxate and tranexamic acid

ArticleYear
Comparative study of cimetidine and cetraxate in the treatment of peptic ulcer.
    Journal of clinical gastroenterology, 1991, Volume: 13, Issue:1

    Topics: Adult; Aged; Anti-Ulcer Agents; Cimetidine; Female; Humans; Male; Middle Aged; Peptic Ulcer; Tranexamic Acid

1991
Cetraxate is not superior to placebo in the treatment of duodenal ulcer.
    Journal of clinical gastroenterology, 1990, Volume: 12, Issue:2

    Topics: Adult; Anti-Ulcer Agents; Cimetidine; Cyclohexanecarboxylic Acids; Double-Blind Method; Duodenal Ulcer; Duodenoscopy; Female; Humans; Male; Middle Aged; Randomized Controlled Trials as Topic; Tranexamic Acid

1990
Healing of gastric ulcer in the elderly: a double-blind study of cetraxate versus ranitidine.
    Journal of clinical gastroenterology, 1989, Volume: 11, Issue:2

    Topics: Aged; Aged, 80 and over; Anti-Ulcer Agents; China; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Double-Blind Method; Female; Hong Kong; Humans; Male; Ranitidine; Stomach Ulcer; Tranexamic Acid

1989
Cetraxate and antacid in the treatment of gastric ulcer. A controlled clinical trial.
    Journal of the Medical Association of Thailand = Chotmaihet thangphaet, 1985, Volume: 68, Issue:7

    Topics: Adult; Aged; Antacids; Anti-Ulcer Agents; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Female; Humans; Male; Middle Aged; Random Allocation; Stomach Ulcer; Tranexamic Acid

1985
Therapeutic effects of cetraxate against acute gastritis and acute aggravation of chronic gastritis. Endoscopic investigation by the double-blind method.
    Arzneimittel-Forschung, 1983, Volume: 33, Issue:8

    Topics: Acute Disease; Anti-Ulcer Agents; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Double-Blind Method; Drug Therapy, Combination; Gastritis; Gastroscopy; Humans; Tranexamic Acid

1983
[Cetraxate in duodenal ulcer, a double-blind clinical study (author's transl)].
    Taiwan yi xue hui za zhi. Journal of the Formosan Medical Association, 1981, Volume: 80, Issue:4

    Topics: Adult; Anti-Ulcer Agents; Clinical Trials as Topic; Cyclohexanecarboxylic Acids; Double-Blind Method; Duodenal Ulcer; Female; Humans; Male; Middle Aged; Tranexamic Acid

1981
Gastric ulcer treatment with intravenous human epidermal growth factor: a double-blind controlled clinical study.
    Journal of gastroenterology and hepatology, 1994, Volume: 9 Suppl 1

    Topics: Administration, Oral; Adolescent; Adult; Aged; Aged, 80 and over; Anti-Ulcer Agents; Double-Blind Method; Epidermal Growth Factor; Female; Humans; Injections, Intravenous; Male; Middle Aged; Stomach Ulcer; Tranexamic Acid

1994
Cetraxate, a mucosal protective agent, combined with omeprazole, amoxycillin, and clarithromycin increases the eradication rate of helicobacter pylori in smokers.
    Alimentary pharmacology & therapeutics, 2000, Volume: 14, Issue:8

    Topics: Adult; Aged; Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer Agents; Clarithromycin; Double-Blind Method; Drug Therapy, Combination; Female; Gastric Mucosa; Helicobacter Infections; Helicobacter pylori; Humans; Male; Middle Aged; Omeprazole; Penicillins; Regional Blood Flow; Smoking; Tranexamic Acid; Treatment Outcome

2000
Influence of Helicobacter pylori infection and cetraxate on gastric mucosal blood flow during healing of endoscopic mucosal resection-induced ulcers.
    Journal of gastroenterology and hepatology, 2001, Volume: 16, Issue:11

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Aged; Aged, 80 and over; Anti-Ulcer Agents; Female; Gastric Mucosa; Gastroscopy; Helicobacter Infections; Helicobacter pylori; Humans; Lansoprazole; Male; Middle Aged; Omeprazole; Regional Blood Flow; Stomach Ulcer; Tranexamic Acid

2001
Comparison of cetraxate-based and pantoprazole-based triple therapies in the treatment of Helicobacter pylori infection.
    Journal of the Chinese Medical Association : JCMA, 2004, Volume: 67, Issue:4

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Aged; Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer Agents; Benzimidazoles; Clarithromycin; Dizziness; Drug Therapy, Combination; Endoscopes, Gastrointestinal; Exanthema; Female; Helicobacter Infections; Helicobacter pylori; Humans; Male; Middle Aged; Multivariate Analysis; Omeprazole; Pantoprazole; Pilot Projects; Prospective Studies; Sulfoxides; Tranexamic Acid; Treatment Outcome

2004
DA-9601 for erosive gastritis: results of a double-blind placebo-controlled phase III clinical trial.
    World journal of gastroenterology, 2004, Aug-15, Volume: 10, Issue:16

    Topics: Adult; Artemisia; Double-Blind Method; Female; Fibrinolytic Agents; Gastritis; Humans; Male; Middle Aged; Phytotherapy; Plant Extracts; Tranexamic Acid; Treatment Outcome

2004
Efficacy of triple therapy plus cetraxate for the Helicobacter pylori eradication in partial gastrectomy patients.
    Digestive diseases and sciences, 2005, Volume: 50, Issue:5

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Aged; Anti-Infective Agents; Anti-Ulcer Agents; Drug Administration Schedule; Drug Therapy, Combination; Female; Gastrectomy; Gastric Stump; Helicobacter Infections; Helicobacter pylori; Humans; Lansoprazole; Male; Middle Aged; Omeprazole; Posture; Tranexamic Acid; Treatment Outcome

2005
Comparison of the effects of cytoprotective drugs on human plasma adrenocorticotropic hormone and cortisol levels with continual stress exposure.
    Biological & pharmaceutical bulletin, 2005, Volume: 28, Issue:11

    Topics: Abietanes; Adrenocorticotropic Hormone; Adult; Anticarcinogenic Agents; Blood Specimen Collection; Fluorescence Polarization Immunoassay; Humans; Hydrocortisone; Hypothalamo-Hypophyseal System; Immunoenzyme Techniques; Male; Pituitary-Adrenal System; Stress, Psychological; Sulpiride; Tranexamic Acid

2005
[Cetraxate hydrochloride (Neuer) induces the effectiveness of new triple therapy in H. pylori eradication].
    Nihon rinsho. Japanese journal of clinical medicine, 2005, Volume: 63 Suppl 11

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer Agents; Clarithromycin; Drug Therapy, Combination; Enzyme Inhibitors; Helicobacter Infections; Helicobacter pylori; Humans; Lansoprazole; Omeprazole; Proton Pump Inhibitors; Tranexamic Acid; Treatment Outcome

2005

Other Studies

45 other study(ies) available for cetraxate and tranexamic acid

ArticleYear
Studies on the mechanism of action of cetraxate [4'-(2-carboxyethyl)phenyl trans-4-aminomethyl cyclohexanecarboxylate hydrochloride], a new anti-ulcer agent.
    Japanese journal of pharmacology, 1979, Volume: 29, Issue:6

    Topics: Acetates; Animals; Anti-Ulcer Agents; Aspirin; Connective Tissue; Cyclohexanecarboxylic Acids; Female; Fibrinolysis; Glycosaminoglycans; Hexosamines; Hydroxyproline; Rats; Sialic Acids; Stomach Ulcer; Tranexamic Acid; Uronic Acids

1979
Therapeutic effect of cetraxate on gastric ulcers (Phase I).
    Gastroenterologia Japonica, 1979, Volume: 14, Issue:3

    Topics: Cyclohexanecarboxylic Acids; Humans; Stomach Ulcer; Tranexamic Acid

1979
Protective effect of cetraxate, a new antiulcer drug, against serotonin-induced ulcer.
    Archives internationales de pharmacodynamie et de therapie, 1979, Volume: 240, Issue:2

    Topics: Animals; Anti-Ulcer Agents; Aorta; Cyclohexanecarboxylic Acids; Gastric Emptying; Gastric Mucosa; Gastrointestinal Motility; Male; Muscle Contraction; Platelet Aggregation; Rats; Regional Blood Flow; Serotonin; Serotonin Antagonists; Stomach Ulcer; Tranexamic Acid

1979
Cetraxate improves ethanol-induced gastric mucosal congestion in anesthetized dogs.
    Japanese journal of pharmacology, 1992, Volume: 60, Issue:1

    Topics: Administration, Topical; Animals; Anti-Ulcer Agents; Blood Volume; Dogs; Ethanol; Gastric Mucosa; Male; Oxygen Consumption; Oxyhemoglobins; Tranexamic Acid

1992
Studies on the mechanism for the gastric mucosal protection by famotidine in rats.
    Japanese journal of pharmacology, 1991, Volume: 55, Issue:2

    Topics: Animals; Anti-Ulcer Agents; Cimetidine; Famotidine; Gastric Mucosa; Male; Pirenzepine; Rats; Rats, Inbred Strains; Regional Blood Flow; Stomach Ulcer; Tranexamic Acid

1991
The role of mucosal prostaglandin levels in healing of water immersion-induced gastric ulcers in rats.
    Scandinavian journal of gastroenterology, 1990, Volume: 25, Issue:1

    Topics: Animals; Anti-Ulcer Agents; Gastric Mucosa; Immersion; Male; Prostaglandins; Rats; Rats, Inbred Strains; Stomach Ulcer; Stress, Physiological; Time Factors; Tranexamic Acid; Wound Healing

1990
Effects of 12-sulfodehydroabietic acid monosodium salt (TA-2711), a new anti-ulcer agent, on gastric mucosal lesions induced by necrotizing agents and gastric mucosal defensive factors in rats.
    Japanese journal of pharmacology, 1990, Volume: 52, Issue:4

    Topics: Abietanes; Animals; Anti-Ulcer Agents; Dinoprostone; Diterpenes; Gastric Acid; Gastric Mucosa; Male; Membrane Potentials; Mucus; Rats; Rats, Inbred Strains; Regional Blood Flow; Stomach Ulcer; Sucralfate; Tranexamic Acid

1990
[Effect of anti-ulcer drugs and PGE2 on the proliferation of rat gastric cultured cells].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1990, Volume: 95, Issue:4

    Topics: Animals; Anti-Ulcer Agents; Blood Substitutes; Cell Division; Cells, Cultured; Cimetidine; Dinoprostone; Dose-Response Relationship, Drug; Female; Gastric Mucosa; Indomethacin; Male; Organic Chemicals; Rats; Rats, Inbred Strains; Thymidine; Tranexamic Acid

1990
Partial purification, and some properties and reactivities of cetraxate benzyl ester hydrochloride-hydrolyzing enzyme.
    Chemical & pharmaceutical bulletin, 1989, Volume: 37, Issue:11

    Topics: Aspergillus niger; Carboxylic Ester Hydrolases; Chromatography, High Pressure Liquid; Cyclohexanecarboxylic Acids; Substrate Specificity; Tranexamic Acid

1989
[The synthesis of 4'-(2-carboxyethyl)phenyl trans-4-aminomethyl cyclohexane carboxylate hydrochloride (cetraxate hydrochloride) by means of enzymatic debenzylation].
    Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 1989, Volume: 109, Issue:3

    Topics: Anti-Ulcer Agents; Aspergillus; Cellulase; Cyclohexanecarboxylic Acids; Methods; Tranexamic Acid

1989
[A study on pathogenesis of gastric ulcer in patient with liver cirrhosis: with special reference to the gastric mucosal blood flow].
    Fukuoka igaku zasshi = Hukuoka acta medica, 1988, Volume: 79, Issue:8

    Topics: Adult; Anti-Ulcer Agents; Gastric Mucosa; Humans; Liver Cirrhosis; Middle Aged; Regional Blood Flow; Stomach Ulcer; Tranexamic Acid

1988
Cytoprotective action of cetraxate against HCl.ethanol-induced gastric lesion in rats.
    Japanese journal of pharmacology, 1988, Volume: 46, Issue:1

    Topics: Animals; Anti-Ulcer Agents; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Ethanol; Gastric Mucosa; Hydrochloric Acid; Indomethacin; Male; Microscopy, Electron, Scanning; Necrosis; Rats; Rats, Inbred Strains; Tranexamic Acid

1988
[Drug administration schedule of anti-ulcer agents to prevent recurrence of peptic ulcer; administration of synergistic drugs for protective factors in peptic ulcer--criteria of drug selection according to clinical symptoms and administration methods].
    Nihon rinsho. Japanese journal of clinical medicine, 1988, Volume: 46, Issue:1

    Topics: Anti-Ulcer Agents; Cyclohexanecarboxylic Acids; Diterpenes; Gefarnate; Humans; Peptic Ulcer; Recurrence; Sucralfate; Tranexamic Acid

1988
[Drug administration schedule of anti-ulcer agents to prevent recurrence of peptic ulcer; combination therapy of inhibitors of attacking factors and synergistic drugs for protective factors in peptic ulcer--selection of drug combinations and clinical effi
    Nihon rinsho. Japanese journal of clinical medicine, 1988, Volume: 46, Issue:1

    Topics: Anti-Ulcer Agents; Cimetidine; Drug Administration Schedule; Drug Therapy, Combination; Gefarnate; Humans; Peptic Ulcer; Ranitidine; Recurrence; Sulpiride; Tranexamic Acid

1988
[Various problems on refractory peptic ulcers; progress of drug therapy and changes in the concept of peptic ulcer].
    Nihon rinsho. Japanese journal of clinical medicine, 1988, Volume: 46, Issue:1

    Topics: Aluminum Hydroxide; Humans; Peptic Ulcer; Prostaglandins E, Synthetic; Sucralfate; Sulpiride; Tranexamic Acid

1988
[Recent developments in synergistic drugs for protective factors in peptic ulcer--clinical efficacy and problems; mucosal blood-flow improving agents].
    Nihon rinsho. Japanese journal of clinical medicine, 1988, Volume: 46, Issue:1

    Topics: Animals; Anti-Ulcer Agents; Gastric Mucosa; Humans; Microcirculation; Peptic Ulcer; Rats; Regional Blood Flow; Secretin; Sulpiride; Tranexamic Acid

1988
[Comparative studies on recurrence and relapse rate in peptic ulcer treated with various types of anti-ulcer agent; synergistic drugs for protective factors in peptic ulcer].
    Nihon rinsho. Japanese journal of clinical medicine, 1988, Volume: 46, Issue:1

    Topics: Age Factors; Aged; Cyclohexanecarboxylic Acids; Humans; Peptic Ulcer; Recurrence; Sucralfate; Tranexamic Acid

1988
Inhibitory effect of prolonged oral administration of cetraxate hydrochloride on experimentally-induced intestinal metaplasia in Wistar rats.
    Arzneimittel-Forschung, 1987, Volume: 37, Issue:9

    Topics: Administration, Oral; Animals; Anti-Ulcer Agents; Cyclohexanecarboxylic Acids; Gastric Acid; Gastric Mucosa; Gastrins; Intestinal Mucosa; Male; Metaplasia; Rats; Rats, Inbred Strains; Regional Blood Flow; Tranexamic Acid

1987
[Effects of troxipide on acute gastric lesions in rats].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1987, Volume: 89, Issue:3

    Topics: Acute Disease; Animals; Anti-Ulcer Agents; Aspirin; Ethanol; Gastric Mucosa; Hydrochloric Acid; Immersion; Male; Piperidines; Rats; Stomach Diseases; Stress, Physiological; Tranexamic Acid

1987
A new screening method for anti-ulcer agents: psychological stress produced by intraspecies emotional communication.
    Pharmacology, 1987, Volume: 34, Issue:2-3

    Topics: Animal Communication; Animals; Anti-Ulcer Agents; Cimetidine; Drug Evaluation, Preclinical; Electroshock; Gastric Mucosa; Gefarnate; Male; Mice; Peptic Ulcer; Stress, Psychological; Tranexamic Acid

1987
Properties and localization of phospholipase A2 activity in rat stomach.
    Biochimica et biophysica acta, 1987, Jun-23, Volume: 919, Issue:3

    Topics: Acyltransferases; Animals; Calcium; Cimetidine; Indomethacin; Kinetics; Lysophospholipase; Male; Phospholipases; Phospholipases A; Phospholipases A2; Rats; Stomach; Substrate Specificity; Tissue Distribution; Tranexamic Acid

1987
Effect of sofalcone on acute gastric mucosal lesions induced by aspirin and ethanol in reference to the biosynthesis of gastric mucosal glycoprotein.
    Research communications in chemical pathology and pharmacology, 1986, Volume: 54, Issue:3

    Topics: Animals; Aspirin; Chalcone; Chalcones; Ethanol; Gastric Mucosa; Gastritis; Glucosamine; Glycoproteins; Male; Propiophenones; Rats; Sulfates; Tranexamic Acid

1986
Anti-ulcer effect of 3-[p-(trans-4-aminomethylcyclohexylcarbonyl) phenyl] propionic acid hydrochloride (TEI-5103).
    Arzneimittel-Forschung, 1985, Volume: 35, Issue:2

    Topics: Acetates; Acetic Acid; Aminopyrine; Animals; Anti-Ulcer Agents; Aspirin; Bethanechol Compounds; Cimetidine; Dogs; Gastric Juice; Gastric Mucosa; Gastrointestinal Hemorrhage; Indomethacin; Male; Phenylpropionates; Pylorus; Rats; Rats, Inbred Strains; Regional Blood Flow; Serotonin; Stomach Ulcer; Stress, Physiological; Tranexamic Acid

1985
[Pharmacokinetic and pharmacological studies on cetraxate, an anti-ulcer agent].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1985, Volume: 85, Issue:5

    Topics: Animals; Anti-Ulcer Agents; Chromatography, High Pressure Liquid; Cyclohexanecarboxylic Acids; Hydroxybenzoates; Kinetics; Lymph; Male; Phenylpropionates; Rabbits; Rats; Rats, Inbred Strains; Stomach Ulcer; Tissue Distribution; Tranexamic Acid

1985
A new broad spectrum inhibitor of esteroproteases, 4-(2-carboxyethyl) phenyl-trans-4-aminomethyl cyclohexane carboxylate hydrochloride (DV 1006).
    The Tohoku journal of experimental medicine, 1972, Volume: 106, Issue:3

    Topics: Antifibrinolytic Agents; Aprotinin; Blood Coagulation; Blood Coagulation Tests; Caseins; Chymotrypsin; Cyclohexanecarboxylic Acids; Esters; Fibrinolysin; Kallikreins; Kinetics; Plasminogen; Protease Inhibitors; Streptokinase; Thrombelastography; Thrombin; Tranexamic Acid; Trypsin Inhibitors

1972
Effect of 2,4-diamino-6-(2,5-dichlorophenyl)-s-triazine maleate (MN-1695) on gastric ulcers and gastric secretion in experimental animals.
    Arzneimittel-Forschung, 1984, Volume: 34, Issue:4

    Topics: Acetates; Acetic Acid; Animals; Anti-Ulcer Agents; Cimetidine; Female; Gastric Acid; Gastric Mucosa; Guinea Pigs; Histamine; Humans; Indomethacin; Male; Mice; Rats; Rats, Inbred Strains; Stomach Ulcer; Stress, Psychological; Tranexamic Acid; Triazines; Ulcer

1984
Effect of 2,4-diamino-6-(2,5-dichlorophenyl)-s-triazine maleate (MN-1695) on gastric mucosal damage induced by various necrotizing agents in rats.
    Arzneimittel-Forschung, 1984, Volume: 34, Issue:4

    Topics: Animals; Anti-Ulcer Agents; Cimetidine; Dinoprostone; Electrolytes; Ethanol; Gastric Acid; Gastric Juice; Gastric Mucosa; Hydrogen-Ion Concentration; Male; Necrosis; Prostaglandins E; Rats; Rats, Inbred Strains; Tranexamic Acid; Triazines

1984
Inhibitors of the acrosomal proteinase acrosin: human urinary trypsin inhibitor (UTI) and 4-(2-carboxyethyl) phenyl trans 4-aminomethylcyclohexanecarboxylate hydrochloride (DV-1006).
    Experientia, 1980, Sep-15, Volume: 36, Issue:9

    Topics: Acrosin; Acrosome; Binding, Competitive; Cyclohexanecarboxylic Acids; Humans; Kinetics; Male; Protease Inhibitors; Spermatozoa; Tranexamic Acid; Trypsin Inhibitors

1980
Efficacy of anti-ulcer drugs on the recovery of gastric mucosal glycoproteins with aspirin-induced gastric damage in rat.
    Gastroenterologia Japonica, 1981, Volume: 16, Issue:4

    Topics: Animals; Anti-Ulcer Agents; Aspirin; Cimetidine; Gastric Mucosa; Glycoproteins; Male; Rats; Rats, Inbred Strains; Tranexamic Acid

1981
[Effects of cimetidine and cetraxate on the biosynthetic activity of mucus glycoproteins in organ culture of rat gastric mucosa (author's transl)].
    Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology, 1981, Volume: 78, Issue:10

    Topics: Animals; Anti-Ulcer Agents; Cimetidine; Cyclohexanecarboxylic Acids; Gastric Mucosa; Glycoproteins; Guanidines; Male; Mucus; Organ Culture Techniques; Rats; Tranexamic Acid

1981
Anti-ulcer effect of 1,6-dihydro-2-[2-(2-methylpropoxy) anilino]-6-oxo-5-pyrimidinecarboxylic acid on experimental gastric ulcers in rats.
    Arzneimittel-Forschung, 1994, Volume: 44, Issue:4

    Topics: Acetates; Animals; Anti-Ulcer Agents; Aspirin; Cimetidine; Ethanol; Hydrochloric Acid; Male; p-Methoxy-N-methylphenethylamine; Pylorus; Pyrimidines; Rats; Rats, Sprague-Dawley; Sodium Hydroxide; Stomach Ulcer; Stress, Psychological; Tranexamic Acid

1994
Endothelin-1-induced gastric ulcer is attenuated by cetraxate.
    Life sciences, 1993, Volume: 53, Issue:7

    Topics: Animals; Anti-Ulcer Agents; Endothelins; Gastric Mucosa; Hemodynamics; Male; Rats; Rats, Wistar; Stomach Ulcer; Tranexamic Acid

1993
Syntheses and inhibitory effects on gastric lesions of 4-guanidinomethylbenzoic acid arylamides.
    Chemical & pharmaceutical bulletin, 1993, Volume: 41, Issue:8

    Topics: Animals; Anti-Ulcer Agents; Benzamides; Guanidines; Male; Mice; Mice, Inbred ICR; Rats; Rats, Sprague-Dawley; Rats, Wistar; Stomach Ulcer; Stress, Psychological; Tranexamic Acid

1993
Syntheses and inhibitory effects on gastric lesions of trans-guanidinomethylcyclohexane carboxylic acid arylamides.
    Chemical & pharmaceutical bulletin, 1993, Volume: 41, Issue:3

    Topics: Animals; Anti-Ulcer Agents; Benzoates; Carbanilides; Cimetidine; Cyclohexanecarboxylic Acids; Gastric Mucosa; Guanidines; Male; Pancreatic Elastase; Rats; Rats, Sprague-Dawley; Stomach Ulcer; Stress, Physiological; Tranexamic Acid; Trypsin Inhibitors

1993
Oxyradical generation from leukocytes during endotoxin-induced microcirculatory disturbance in rat mesentery--attenuating effect of cetraxate.
    Toxicology and applied pharmacology, 1993, Volume: 120, Issue:1

    Topics: Animals; Blood Flow Velocity; Endotoxins; Erythrocytes; Granulocytes; In Vitro Techniques; Leukocytes; Luminescent Measurements; Male; Mesentery; Microcirculation; Microscopy, Fluorescence; Rats; Rats, Wistar; Respiratory Burst; Tetradecanoylphorbol Acetate; Tranexamic Acid

1993
Prevention of water immersion stress-induced gastric lesions through the enhancement of nitric oxide synthase activity in rats.
    Alimentary pharmacology & therapeutics, 1996, Volume: 10, Issue:1

    Topics: Animals; Anti-Ulcer Agents; Gastric Mucosa; Immersion; Male; Nitric Oxide Synthase; omega-N-Methylarginine; Prostaglandins; Rats; Rats, Wistar; Stomach Ulcer; Stress, Psychological; Tranexamic Acid

1996
Effect of 1,6-dihydro-2[2-(2-methylpropoxy)anilino]-6-oxo-5-pyrimidineca rboxyli c acid on ethanol-induced microvascular injury in rats.
    Arzneimittel-Forschung, 1996, Volume: 46, Issue:8

    Topics: Animals; Anti-Ulcer Agents; Capillary Permeability; Disease Models, Animal; Ethanol; Gastric Mucosa; Guinea Pigs; Histamine Release; Leukotriene C4; Male; Pyrimidines; Rats; Rats, Sprague-Dawley; Tranexamic Acid

1996
Geranylgeranylacetone and cetraxate hydrochloride increase UDP-galactosyltransferase activity in rat gastric mucosa.
    Acta medica Okayama, 1997, Volume: 51, Issue:5

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Diterpenes; Galactosyltransferases; Gastric Mucosa; Male; Prostaglandins; Rats; Rats, Sprague-Dawley; Tranexamic Acid

1997
Effect of Saiboku-to, an Oriental Herbal Medicine, on gastric lesion induced by restraint water-immersion stress or by ethanol treatment.
    The Journal of pharmacy and pharmacology, 1999, Volume: 51, Issue:4

    Topics: Animals; Anti-Anxiety Agents; Anti-Ulcer Agents; Atropine; Diazepam; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Ethanol; Gastric Juice; Gastric Mucosa; Hexosamines; Immersion; Irritants; Ligation; Male; Medicine, Chinese Traditional; Medicine, Kampo; Parasympatholytics; Pylorus; Rats; Rats, Sprague-Dawley; Restraint, Physical; Stomach; Stomach Diseases; Stress, Physiological; Tranexamic Acid; Water

1999
Purification and characterization of a novel esterase promising for the production of useful compounds from Microbacterium sp. 7-1W.
    FEMS microbiology letters, 2002, Jan-10, Volume: 206, Issue:2

    Topics: Actinomycetales; Enzyme Stability; Esterases; Esters; Membrane Proteins; Pantothenic Acid; Sequence Analysis, Protein; Substrate Specificity; Tranexamic Acid

2002
Enzymatic preparation of D-beta-acetylthioisobutyric acid and cetraxate hydrochloride using a stereo- and/or regioselective hydrolase, 3,4-dihydrocoumarin hydrolase from Acinetobacter calcoaceticus.
    Applied microbiology and biotechnology, 2002, Volume: 60, Issue:3

    Topics: Acinetobacter calcoaceticus; Butyrates; Escherichia coli; Hydrolases; Hydrolysis; Molecular Conformation; Substrate Specificity; Tranexamic Acid

2002
Biocatalytic deprotection of a cetraxate ester by Microbacterium sp. strain 7-1W cells.
    Bioscience, biotechnology, and biochemistry, 2003, Volume: 67, Issue:1

    Topics: Catalysis; Esterases; Esters; Filtration; Gram-Positive Bacteria; Hydrogen-Ion Concentration; Hydrolysis; Temperature; Tranexamic Acid

2003
[Preface to the appearence of the Neue Osterreichische Zeitschrift für Kinderheilkunde].
    Neue osterreichische Zeitschrift fur Kinderheilkunde, 1955, Volume: 1, Issue:1

    Topics: Child; Humans; Pediatrics; Periodicals as Topic; Tranexamic Acid

1955
Cetraxate raises levels of calcitonin gene-related peptide and substance P in human plasma.
    The Journal of pharmacy and pharmacology, 2004, Volume: 56, Issue:4

    Topics: Adult; Anti-Ulcer Agents; Calcitonin Gene-Related Peptide; Humans; Male; Substance P; Tranexamic Acid

2004
Are gastroprotective drugs useful for gastric ulcer healing: re-evaluation using current ICH E9 guidelines.
    Inflammopharmacology, 2007, Volume: 15, Issue:1

    Topics: Anti-Ulcer Agents; Gastric Mucosa; Guidelines as Topic; Humans; Randomized Controlled Trials as Topic; Research Design; Retrospective Studies; Stomach Ulcer; Tranexamic Acid

2007