cetirizine and diphenhydramine

cetirizine has been researched along with diphenhydramine in 45 studies

Research

Studies (45)

TimeframeStudies, this research(%)All Research%
pre-19901 (2.22)18.7374
1990's9 (20.00)18.2507
2000's10 (22.22)29.6817
2010's19 (42.22)24.3611
2020's6 (13.33)2.80

Authors

AuthorsStudies
Carrupt, PA; Jolliet, P; Morin, C; Morin, D; Pagliara, A; Rihoux, JP; Testa, B; Tillement, JP; Urien, S1
Carrupt, PA; Crivori, P; Cruciani, G; Testa, B1
Keserü, GM1
Nagashima, R; Nishikawa, T; Tobita, M1
Jia, L; Sun, H1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Sen, S; Sinha, N1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Gabos, C; Gengo, FM; Mechtler, L1
Berman, BA1
Samuels, LL; Sheffer, AL1
Gabos, C; Gengo, FM1
O'Hanlon, JF; Ramaekers, JG1
Muehlbach, MJ; Schweitzer, PK; Walsh, JK1
Naclerio, RM1
Woosley, RL1
Fraser, TG; Maher, J; Pillay, N; Simons, FE; Simons, KJ1
Basavaiah, K; Charan, VS1
Aarab, M; Bijtjes, SI; De Weert, AM; Eijken, EJ; van Oosterwijck, AW; Verbaten, MN; Verster, JC; Volkerts, ER2
Fujii, Y; Harada, C; Hirai, T; Kamei, C; Tanaka, T1
Chung, D; Godbold, JH; Park, JH; Sampson, HA; Wang, J1
Masuda, F; Matsuki, N; Nomura, H; Nonaka, A1
Arnold, AA; Dufourc, EJ; Gravel, AE; Marcotte, I1
Zakaria, K1
Gram, DW; Pariser, MS1
Douroumis, D; Scoutaris, N; Snowden, M1
Grobosch, T; Hiraoka, K; Inami, A; Komamura, H; Matsuda, R; Maurer, M; Miyake, M; Takeda, K; Tashiro, M; Yamada, Y; Yanai, K1
Bernstein, JA; de la Cruz, AA; Geh, EN; Ghosh, D; Stelma, G1
Emsley, L; Hirsh, DA; Rossini, AJ; Schurko, RW1
Biagi, C; Calamelli, E; Cipriani, F; Donati, M; Melis, M; Monaco, L; Motola, D; Ricci, G; Vaccheri, A1
Copenhaver, C; Iweala, OI; Moran, TP; Wu, EY1
Hiraoka, K; Inami, A; Ito, T; Kikuchi, A; Koike, D; Matsuda, R; Maurer, M; Miyake, M; Mohsen, A; Nasir, FBM; Sasakawa, J; Takeda, K; Tashiro, M; Watabe, H; Watanuki, S; Yanai, K1
Durham, CG; Foster, J; Herrington, JD; Sager, L; Thotakura, D1
Arndt, N; Cipriani, VP; Conte, WL; Dellaria, A; Javed, A1
Carter, MC; Diaz, LZ; Jenkinson, HA; Levy, ML; Lundgren, AD1
Banovic, F; Blubaugh, A; Denley, T; Lemo, N; Papich, MG; Scheibe, I1
Abella, BS; Berger, WE; Blaiss, MS; Caterino, JM; Du, J; Herres, JP; Kessler, A; Klausner, HA; Moellman, JJ; Stiell, IG; Suner, S1
He, X; O'Shea, KE1
Bernstein, JA; Blaiss, MS; Camargo, CA; Fulgham, P; Haumschild, R; Kessler, A; Moellman, J; Pines, JM; Rupp, K; Tyler, T1
Beaucage-Charron, J; Bouchard, P; Charpentier, F; Gaudet, L; Lamothe, S; Lordkipanidzé, M; Pelletier, C; Pépin, AS; Picard, M; Projean, D; Roy, V1
Aizawa, M; Asada, A; Fujimura, R; Kazama, I1

Reviews

6 review(s) available for cetirizine and diphenhydramine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Perennial allergic rhinitis: clinical efficacy of a new antihistamine.
    The Journal of allergy and clinical immunology, 1990, Volume: 86, Issue:6 Pt 2

    Topics: Benzhydryl Compounds; Cetirizine; Diphenhydramine; Dose-Response Relationship, Drug; Histamine H1 Antagonists; Humans; Hydroxyzine; Rhinitis, Allergic, Perennial; Terfenadine

1990
Cetirizine: antiallergic therapy beyond traditional H1 antihistamines.
    The Journal of allergy and clinical immunology, 1990, Volume: 86, Issue:6 Pt 2

    Topics: Cetirizine; Diphenhydramine; Histamine H1 Antagonists; Humans; Hydroxyzine; Hypersensitivity; Reaction Time

1990
Cardiac actions of antihistamines.
    Annual review of pharmacology and toxicology, 1996, Volume: 36

    Topics: Animals; Astemizole; Cetirizine; Diphenhydramine; Drug Interactions; Histamine H1 Antagonists; Humans; Hydroxyzine; Loratadine; Terfenadine; Torsades de Pointes

1996
Management of a neonate with diffuse cutaneous mastocytosis: Case report and literature review.
    Pediatric dermatology, 2019, Volume: 36, Issue:4

    Topics: Cetirizine; Diphenhydramine; Drug Therapy, Combination; Gene Expression Regulation, Developmental; Humans; Infant, Newborn; Male; Mastocytosis; Prognosis; Proto-Oncogene Mas; Proto-Oncogene Proteins c-kit; Ranitidine; Severity of Illness Index; Treatment Outcome

2019
The Role of Cetirizine in the Changing Landscape of IV Antihistamines: A Narrative Review.
    Advances in therapy, 2022, Volume: 39, Issue:1

    Topics: Administration, Intravenous; Adult; Cetirizine; Diphenhydramine; Histamine H1 Antagonists; Humans; Urticaria

2022

Trials

14 trial(s) available for cetirizine and diphenhydramine

ArticleYear
Quantitative effects of cetirizine and diphenhydramine on mental performance measured using an automobile driving simulator.
    Annals of allergy, 1990, Volume: 64, Issue:6

    Topics: Automobile Driving; Cetirizine; Diphenhydramine; Histamine H1 Antagonists; Humans; Hydroxyzine; Psychomotor Performance; Reaction Time; Sleep Stages

1990
Antihistamines, drowsiness, and psychomotor impairment: central nervous system effect of cetirizine.
    Annals of allergy, 1987, Volume: 59, Issue:6 Pt 2

    Topics: Automobile Driving; Brain; Cetirizine; Clinical Trials as Topic; Diphenhydramine; Double-Blind Method; Histamine H1 Antagonists; Humans; Hydroxyzine; Psychomotor Performance; Random Allocation; Reaction Time; Research Design; Sleep Stages

1987
Antihistamine effects on actual driving performance in a standard test: a summary of Dutch experience, 1989-94.
    Allergy, 1995, Volume: 50, Issue:3

    Topics: Automobile Driving; Benzimidazoles; Butyrophenones; Cetirizine; Clemastine; Diphenhydramine; Dose-Response Relationship, Drug; Histamine H1 Antagonists; Humans; Loratadine; Netherlands; Piperidines; Psychomotor Performance; Terfenadine; Triprolidine

1995
Sleepiness and performance during three-day administration of cetirizine or diphenhydramine.
    The Journal of allergy and clinical immunology, 1994, Volume: 94, Issue:4

    Topics: Adult; Cetirizine; Diphenhydramine; Double-Blind Method; Female; Humans; Male; Reaction Time; Sleep Stages; Task Performance and Analysis; Time Factors

1994
The effect of antihistamines on the immediate allergic response: a comparative review.
    Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery, 1993, Volume: 108, Issue:6

    Topics: Capillary Permeability; Cetirizine; Cyproheptadine; Diphenhydramine; Double-Blind Method; Histamine H1 Antagonists; Humans; Ketotifen; Mast Cells; Peptide Hydrolases; Phthalazines; Rhinitis, Allergic, Seasonal; Sneezing; Terfenadine

1993
Central nervous system effects of H1-receptor antagonists in the elderly.
    Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 1999, Volume: 82, Issue:2

    Topics: Aged; Blood Glucose; Brain; Cetirizine; Chlorpheniramine; Cognition Disorders; Cross-Over Studies; Diphenhydramine; Double-Blind Method; Event-Related Potentials, P300; Female; Histamine H1 Antagonists; Histamine H2 Antagonists; Humans; Loratadine; Male; Memory Disorders; Psychomotor Performance; Safety; Skin Tests; Sleep Stages

1999
Acute and subchronic effects of levocetirizine and diphenhydramine on memory functioning, psychomotor performance, and mood.
    The Journal of allergy and clinical immunology, 2003, Volume: 111, Issue:3

    Topics: Acetates; Adult; Affect; Cetirizine; Cross-Over Studies; Diphenhydramine; Double-Blind Method; Female; Histamine H1 Antagonists; Humans; Male; Memory; Piperazines; Psychomotor Performance; Reference Values; Time Factors

2003
Driving ability after acute and sub-chronic administration of levocetirizine and diphenhydramine: a randomized, double-blind, placebo-controlled trial.
    Psychopharmacology, 2003, Volume: 169, Issue:1

    Topics: Adult; Automobile Driving; Cetirizine; Diphenhydramine; Dose-Response Relationship, Drug; Double-Blind Method; Female; Histamine H1 Antagonists; Histamine H1 Antagonists, Non-Sedating; Humans; Male; Piperazines

2003
Comparison of cetirizine and diphenhydramine in the treatment of acute food-induced allergic reactions.
    The Journal of allergy and clinical immunology, 2011, Volume: 128, Issue:5

    Topics: Acute Disease; Adolescent; Anti-Allergic Agents; Cetirizine; Child; Child, Preschool; Diphenhydramine; Food Hypersensitivity; Humans; Hypnotics and Sedatives; Young Adult

2011
A simulated car-driving study on the effects of acute administration of levocetirizine, fexofenadine, and diphenhydramine in healthy Japanese volunteers.
    Human psychopharmacology, 2016, Volume: 31, Issue:3

    Topics: Adult; Asian People; Automobile Driving; Cetirizine; Cross-Over Studies; Diphenhydramine; Double-Blind Method; Female; Histamine H1 Antagonists; Histamine H1 Antagonists, Non-Sedating; Humans; Male; Psychomotor Performance; Reaction Time; Terfenadine; Young Adult

2016
Effects of levocetirizine and diphenhydramine on regional glucose metabolic changes and hemodynamic responses in the human prefrontal cortex during cognitive tasks.
    Human psychopharmacology, 2018, Volume: 33, Issue:2

    Topics: Brain Mapping; Cetirizine; Cognition; Cross-Over Studies; Diphenhydramine; Double-Blind Method; Female; Fluorodeoxyglucose F18; Glucose; Healthy Volunteers; Hemodynamics; Histamine H1 Antagonists; Humans; Image Processing, Computer-Assisted; Male; Neuropsychological Tests; Positron-Emission Tomography; Prefrontal Cortex; Spectroscopy, Near-Infrared; Time Factors

2018
Effect of diphenhydramine and cetirizine on immediate and late-phase cutaneous allergic reactions in healthy dogs: a randomized, double-blinded crossover study.
    Veterinary dermatology, 2020, Volume: 31, Issue:4

    Topics: Animals; Cetirizine; Cross-Over Studies; Diphenhydramine; Dog Diseases; Dogs; Double-Blind Method; Histamine; Histamine H1 Antagonists; Hypersensitivity; Male; p-Methoxy-N-methylphenethylamine; Skin; Skin Tests

2020
Intravenous Cetirizine Versus Intravenous Diphenhydramine for the Treatment of Acute Urticaria: A Phase III Randomized Controlled Noninferiority Trial.
    Annals of emergency medicine, 2020, Volume: 76, Issue:4

    Topics: Administration, Intravenous; Adolescent; Adult; Aged; Aged, 80 and over; Canada; Cetirizine; Diphenhydramine; Double-Blind Method; Female; Humans; Male; Middle Aged; Treatment Outcome; United States; Urticaria

2020
A randomized double-blind feasibility study comparing cetirizine and diphenhydramine in the prevention of paclitaxel-associated infusion-related reactions: the PREMED-F1 study.
    Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2022, Volume: 30, Issue:4

    Topics: Cetirizine; Diphenhydramine; Double-Blind Method; Feasibility Studies; Humans; Paclitaxel; Premedication; Prospective Studies

2022

Other Studies

25 other study(ies) available for cetirizine and diphenhydramine

ArticleYear
Molecular properties and pharmacokinetic behavior of cetirizine, a zwitterionic H1-receptor antagonist.
    Journal of medicinal chemistry, 1998, Mar-12, Volume: 41, Issue:6

    Topics: Alkanes; Animals; Biological Transport; Blood Proteins; Brain; Cetirizine; Histamine H1 Antagonists; Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydroxyzine; Isomerism; Models, Molecular; Molecular Conformation; Octanols; Rats; Water

1998
Predicting blood-brain barrier permeation from three-dimensional molecular structure.
    Journal of medicinal chemistry, 2000, Jun-01, Volume: 43, Issue:11

    Topics: Blood-Brain Barrier; Databases, Factual; Models, Chemical; Molecular Conformation; Multivariate Analysis; Permeability; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Prediction of hERG potassium channel affinity by traditional and hologram qSAR methods.
    Bioorganic & medicinal chemistry letters, 2003, Aug-18, Volume: 13, Issue:16

    Topics: Cation Transport Proteins; Databases, Factual; Discriminant Analysis; Ether-A-Go-Go Potassium Channels; Holography; Linear Models; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Voltage-Gated; Quantitative Structure-Activity Relationship

2003
A discriminant model constructed by the support vector machine method for HERG potassium channel inhibitors.
    Bioorganic & medicinal chemistry letters, 2005, Jun-02, Volume: 15, Issue:11

    Topics: Animals; CHO Cells; Cricetinae; Discriminant Analysis; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Potassium Channel Blockers; Potassium Channels, Voltage-Gated

2005
Support vector machines classification of hERG liabilities based on atom types.
    Bioorganic & medicinal chemistry, 2008, Jun-01, Volume: 16, Issue:11

    Topics: Animals; Arrhythmias, Cardiac; CHO Cells; Computer Simulation; Cricetinae; Cricetulus; Discriminant Analysis; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Models, Chemical; Patch-Clamp Techniques; Potassium Channel Blockers; Potassium Channels, Voltage-Gated; Predictive Value of Tests; ROC Curve

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Predicting hERG activities of compounds from their 3D structures: development and evaluation of a global descriptors based QSAR model.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:2

    Topics: Computer Simulation; Ether-A-Go-Go Potassium Channels; Humans; Molecular Structure; Organic Chemicals; Quantitative Structure-Activity Relationship

2011
Newer antihistamines.
    The Medical letter on drugs and therapeutics, 2001, Apr-30, Volume: 43, Issue:1103

    Topics: Administration, Oral; Anti-Allergic Agents; Cetirizine; Chlorpheniramine; Conscious Sedation; Diphenhydramine; Dose-Response Relationship, Drug; Histamine H1 Antagonists; Humans; Hypersensitivity; Loratadine; Psychomotor Performance; Rhinitis, Allergic, Seasonal; Somnambulism; Terfenadine

2001
Titrimetric and spectrophotometric assay of some antihistamines through the determination of the chloride of their hydrochlorides.
    Farmaco (Societa chimica italiana : 1989), 2002, Volume: 57, Issue:1

    Topics: Cetirizine; Chemistry, Pharmaceutical; Chlorides; Diphenhydramine; Histamine H1 Antagonists; Hydroxyzine; Spectrophotometry; Tablets; Titrimetry

2002
Epileptogenic activity induced by histamine H(1) antagonists in amygdala-kindled rats.
    Brain research, 2003, Nov-21, Volume: 991, Issue:1-2

    Topics: Amygdala; Animals; Cetirizine; Diphenhydramine; Electroencephalography; Epilepsy; Histamine H1 Antagonists; Injections, Intraperitoneal; Ketotifen; Kindling, Neurologic; Loratadine; Male; Pyrilamine; Rats; Rats, Wistar

2003
Best drugs for what ails you: the brands to buy--and those to skip.
    Consumer reports, 2009, Volume: 74, Issue:9

    Topics: Acetaminophen; Anesthetics, Local; Cetirizine; Chlorpheniramine; Common Cold; Cough; Dextromethorphan; Diphenhydramine; Drug Costs; Drug Therapy; Emergencies; Expectorants; First Aid; Glycerol; Guaifenesin; Histamine Antagonists; Honey; Humans; Hypersensitivity; Ibuprofen; Influenza Vaccines; Influenza, Human; Loratadine; Nonprescription Drugs; Oxymetazoline; Pharyngitis; Propiophenones; Pseudoephedrine; Rhinitis; Sodium Chloride

2009
Ahh-choo! How to sneeze at allergies.
    Consumer reports, 2010, Volume: 75, Issue:5

    Topics: Adrenal Cortex Hormones; Cetirizine; Diphenhydramine; Health Behavior; Health Care Surveys; Histamine Antagonists; Histamine H1 Antagonists; Histamine H1 Antagonists, Non-Sedating; Humans; Leukotriene Antagonists; Loratadine; Nasal Decongestants; Nonprescription Drugs; Prescription Drugs; Pseudoephedrine; Rhinitis, Allergic, Seasonal

2010
Impairment of fear memory consolidation and expression by antihistamines.
    Brain research, 2013, Feb-01, Volume: 1493

    Topics: Amygdala; Animals; Behavior, Animal; Cetirizine; Conditioning, Psychological; Dibenzoxepins; Diphenhydramine; Electroshock; Extinction, Psychological; Fear; Freezing Reaction, Cataleptic; Histamine Antagonists; Histamine H1 Antagonists; Histamine H1 Antagonists, Non-Sedating; Male; Memory; Mice; Mice, Inbred C57BL; Olopatadine Hydrochloride

2013
An NMR investigation of the structure, function and role of the hERG channel selectivity filter in the long QT syndrome.
    Biochimica et biophysica acta, 2013, Volume: 1828, Issue:6

    Topics: Bepridil; Cetirizine; Dimyristoylphosphatidylcholine; Diphenhydramine; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Fluvoxamine; Humans; Ion Channel Gating; Long QT Syndrome; Magnetic Resonance Spectroscopy; Membranes, Artificial; Phosphatidylcholines; Potassium; Promethazine; Protein Conformation; Structure-Activity Relationship

2013
Pruritic erythematous plaques.
    American family physician, 2014, Sep-01, Volume: 90, Issue:5

    Topics: Aged; Anti-Allergic Agents; Cetirizine; Diagnosis, Differential; Diphenhydramine; Female; Humans; Mycosis Fungoides; Pruritus; Treatment Failure

2014
Urticaria pigmentosa-like disease in a dog.
    The Canadian veterinary journal = La revue veterinaire canadienne, 2015, Volume: 56, Issue:3

    Topics: Animals; Anti-Allergic Agents; Anti-Ulcer Agents; Cetirizine; Diphenhydramine; Dog Diseases; Dogs; Famotidine; Male; Urticaria Pigmentosa

2015
Taste masked thin films printed by jet dispensing.
    International journal of pharmaceutics, 2015, Oct-30, Volume: 494, Issue:2

    Topics: Administration, Oral; Cetirizine; Computer Systems; Diphenhydramine; Drug Delivery Systems; Humans; Ibuprofen; Taste; Technology, Pharmaceutical

2015
Sensitization of a child to Cyanobacteria after recreational swimming in a lake.
    The Journal of allergy and clinical immunology, 2016, Volume: 137, Issue:6

    Topics: Acrodermatitis; Cetirizine; Child; Cyanobacteria; Diphenhydramine; Female; Humans; Lakes; Swimming

2016
    Physical chemistry chemical physics : PCCP, 2016, Sep-21, Volume: 18, Issue:37

    Topics: Ambroxol; Cetirizine; Chlorine; Diphenhydramine; Histidine; Isoxsuprine; Magnetic Resonance Spectroscopy; Mass Spectrometry; Pharmaceutical Preparations; Salts; X-Ray Diffraction

2016
Safety profile of H1-antihistamines in pediatrics: an analysis based on data from VigiBase.
    Pharmacoepidemiology and drug safety, 2017, Volume: 26, Issue:10

    Topics: Adolescent; Adverse Drug Reaction Reporting Systems; Cetirizine; Child; Child Mortality; Child, Preschool; Chlorpheniramine; Databases, Factual; Diphenhydramine; Epilepsy; Female; Histamine H1 Antagonists; Humans; Infant; Infant, Newborn; Loratadine; Male; Pharmacovigilance; Stevens-Johnson Syndrome; World Health Organization

2017
Hydroxychloroquine as a steroid-sparing agent in an infant with chronic urticaria.
    Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 2018, Volume: 120, Issue:1

    Topics: Acetates; Anti-Inflammatory Agents; Antimalarials; Cetirizine; Chronic Disease; Cyclopropanes; Diphenhydramine; Drug Resistance; Histamine Antagonists; Humans; Hydroxychloroquine; Infant; Male; Quinolines; Ranitidine; Skin; Sulfides; Urticaria

2018
Cetirizine versus diphenhydramine in the prevention of chemotherapy-related hypersensitivity reactions.
    Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners, 2019, Volume: 25, Issue:6

    Topics: Aged; Antineoplastic Agents, Immunological; Antineoplastic Agents, Phytogenic; Cetirizine; Cetuximab; Diphenhydramine; Drug Hypersensitivity; Female; Histamine H1 Antagonists, Non-Sedating; Humans; Infusions, Intravenous; Male; Middle Aged; Paclitaxel; Premedication; Prospective Studies; Retrospective Studies; Rituximab

2019
Reduction in ocrelizumab-induced infusion reactions by a modified premedication protocol.
    Multiple sclerosis and related disorders, 2019, Volume: 27

    Topics: Acetaminophen; Administration, Intravenous; Adult; Age Factors; Anti-Inflammatory Agents; Antibodies, Monoclonal, Humanized; Body Mass Index; Cetirizine; Diphenhydramine; Female; Humans; Immunologic Factors; Male; Methylprednisolone; Middle Aged; Multiple Sclerosis; Premedication; Ranitidine; Sex Factors; Treatment Outcome; Young Adult

2019
Rapid transformation of H
    Journal of hazardous materials, 2020, Nov-05, Volume: 398

    Topics: Cetirizine; Diphenhydramine; Histamine Antagonists; Oxidation-Reduction; Peroxides; Water Pollutants, Chemical

2020
Cetirizine more potently exerts mast cell-stabilizing property than diphenhydramine.
    Drug discoveries & therapeutics, 2022, Nov-20, Volume: 16, Issue:5

    Topics: Animals; Anti-Allergic Agents; Cetirizine; Diphenhydramine; Histamine H1 Antagonists; Mast Cells; Rats

2022