cetirizine and cimetidine

cetirizine has been researched along with cimetidine in 20 studies

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's7 (35.00)18.2507
2000's6 (30.00)29.6817
2010's7 (35.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Carrupt, PA; Crivori, P; Cruciani, G; Testa, B1
Bakker, RA; Leurs, R; Lim, HD; Ling, P; Thurmond, RL; van Rijn, RM1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Benet, LZ; Brouwer, KL; Chu, X; Dahlin, A; Evers, R; Fischer, V; Giacomini, KM; Hillgren, KM; Hoffmaster, KA; Huang, SM; Ishikawa, T; Keppler, D; Kim, RB; Lee, CA; Niemi, M; Polli, JW; Sugiyama, Y; Swaan, PW; Tweedie, DJ; Ware, JA; Wright, SH; Yee, SW; Zamek-Gliszczynski, MJ; Zhang, L1
Avdeef, A; Tam, KY1
Chen, X; Lin, X; Skolnik, S; Wang, J1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR1
Giacomini, KM; Huang, Y; Khuri, N; Kido, Y; Kosaka, A; Morrissey, KM; Sali, A; Wittwer, MB; Zhang, X; Zur, AA1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Simons, FE; Simons, KJ; Sussman, GL1
Gregorowski, MD; Snyman, JR; Sommers, DK1
Chen, X; Simons, FE; Simons, KJ1
Bach, FW; Kjaer, A; Knigge, U; Madsen, EL; Søe-Jensen, P; Warberg, J1
Corbel, S; Dy, M1
Behar, M; Cantagrel, A; Kahn, MF; Laroche, M; Mazières, B; Rolland, Y1
Grossmann, M; Jamieson, MJ; Kirch, W1
Dux, M; Messlinger, K; Schwenger, N1
Aiba, S; Kawamoto, Y; Mizuashi, M; Ohtani, T; Tagami, H1
Yu, L; Zeng, S1

Reviews

2 review(s) available for cetirizine and cimetidine

ArticleYear
Membrane transporters in drug development.
    Nature reviews. Drug discovery, 2010, Volume: 9, Issue:3

    Topics: Animals; Computer Simulation; Decision Trees; Drug Approval; Drug Discovery; Drug Evaluation, Preclinical; Drug Interactions; Humans; Membrane Transport Proteins; Mice; Mice, Knockout; Prescription Drugs

2010
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Trials

2 trial(s) available for cetirizine and cimetidine

ArticleYear
Effect of the H2-antagonist cimetidine on the pharmacokinetics and pharmacodynamics of the H1-antagonists hydroxyzine and cetirizine in patients with chronic urticaria.
    The Journal of allergy and clinical immunology, 1995, Volume: 95, Issue:3

    Topics: Adolescent; Adult; Aged; Cetirizine; Chronic Disease; Cimetidine; Double-Blind Method; Drug Combinations; Drug Interactions; Female; Humans; Hydroxyzine; Male; Middle Aged; Skin Tests; Urticaria

1995
Histamine response and local cooling in the human skin: involvement of H1- and H2-receptors.
    British journal of clinical pharmacology, 1999, Volume: 48, Issue:2

    Topics: Adult; Cetirizine; Cimetidine; Cold Temperature; Cross-Over Studies; Double-Blind Method; Female; Histamine H1 Antagonists; Histamine H2 Antagonists; Histamine Release; Humans; Iontophoresis; Laser-Doppler Flowmetry; Male; Receptors, Histamine H1; Receptors, Histamine H2; Regional Blood Flow; Skin; Skin Physiological Phenomena

1999

Other Studies

16 other study(ies) available for cetirizine and cimetidine

ArticleYear
Predicting blood-brain barrier permeation from three-dimensional molecular structure.
    Journal of medicinal chemistry, 2000, Jun-01, Volume: 43, Issue:11

    Topics: Blood-Brain Barrier; Databases, Factual; Models, Chemical; Molecular Conformation; Multivariate Analysis; Permeability; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Evaluation of histamine H1-, H2-, and H3-receptor ligands at the human histamine H4 receptor: identification of 4-methylhistamine as the first potent and selective H4 receptor agonist.
    The Journal of pharmacology and experimental therapeutics, 2005, Volume: 314, Issue:3

    Topics: Cell Line; Histamine Agonists; Humans; Imidazoles; Indoles; Isothiuronium; Ligands; Methylhistamines; Piperazines; Radioligand Assay; Receptors, G-Protein-Coupled; Receptors, Histamine; Receptors, Histamine H1; Receptors, Histamine H2; Receptors, Histamine H3; Receptors, Histamine H4

2005
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
How well can the Caco-2/Madin-Darby canine kidney models predict effective human jejunal permeability?
    Journal of medicinal chemistry, 2010, May-13, Volume: 53, Issue:9

    Topics: Animals; Disease Models, Animal; Dogs; Humans; Jejunal Diseases; Kidney Diseases; Models, Biological; Permeability; Porosity; Regression Analysis

2010
Attenuation of intestinal absorption by major efflux transporters: quantitative tools and strategies using a Caco-2 model.
    Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:2

    Topics: Adenosine; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Sub-Family B Member 4; ATP-Binding Cassette Transporters; Biological Transport; Caco-2 Cells; Chromatography, Liquid; Dibenzocycloheptenes; Diketopiperazines; Drug Discovery; Heterocyclic Compounds, 4 or More Rings; Humans; Intestinal Absorption; Mass Spectrometry; Models, Biological; Neoplasm Proteins; Pharmaceutical Preparations; Predictive Value of Tests; Propionates; Quinolines; Substrate Specificity

2011
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
    Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10

    Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection

2012
Discovery of potent, selective multidrug and toxin extrusion transporter 1 (MATE1, SLC47A1) inhibitors through prescription drug profiling and computational modeling.
    Journal of medicinal chemistry, 2013, Feb-14, Volume: 56, Issue:3

    Topics: Computer Simulation; Fluorescent Dyes; Organic Cation Transport Proteins; Prescription Drugs

2013
Influence of histamine receptor antagonists on the dynamics of the cutaneous hypersensitivity reaction in patients infected with schistosoma haematobium.
    European journal of clinical pharmacology, 1993, Volume: 44, Issue:5

    Topics: Adolescent; Adult; Antibodies, Helminth; Betahistine; Cetirizine; Cimetidine; Dermatitis, Allergic Contact; Histamine H1 Antagonists; Histamine H2 Antagonists; Humans; Male; Schistosomiasis haematobia

1993
Effect of the H2-receptor antagonist cimetidine, on the pharmacokinetics and pharmacodynamics of the H1-receptor antagonists hydroxyzine and cetirizine in rabbits.
    Pharmaceutical research, 1994, Volume: 11, Issue:2

    Topics: Alanine Transaminase; Analysis of Variance; Animals; Aspartate Aminotransferases; Cetirizine; Chromatography, High Pressure Liquid; Cimetidine; Drug Synergism; Half-Life; Hydroxyzine; Hypersensitivity, Immediate; Injections, Intravenous; L-Lactate Dehydrogenase; Liver; Rabbits

1994
Insulin/hypoglycemia-induced adrenocorticotropin and beta-endorphin release: involvement of hypothalamic histaminergic neurons.
    Endocrinology, 1993, Volume: 132, Issue:5

    Topics: Adrenocorticotropic Hormone; Animals; beta-Endorphin; Cetirizine; Cimetidine; Histamine; Histamine Agonists; Histamine Antagonists; Hypoglycemia; Hypothalamus; Insulin; Male; Methylhistamines; Neurons; Pyrilamine; Pyrimidinones; Rats; Rats, Wistar

1993
Evidence for bidirectional histamine transport by murine hematopoietic progenitor cells.
    FEBS letters, 1996, Aug-12, Volume: 391, Issue:3

    Topics: Animals; Biological Transport; Calcium; Cell Line; Cetirizine; Cimetidine; Female; Hematopoietic Stem Cells; Histamine; Histamine Antagonists; Interleukin-3; Male; Mice; Mice, Inbred C57BL; Piperidines; Pyrimidinones; Sodium

1996
Does the atopic ("allergic") rheumatism of NERDS really exist? Report of a case.
    Revue du rhumatisme (English ed.), 1997, Volume: 64, Issue:10

    Topics: Adult; Cetirizine; Cimetidine; Dermatitis; Diagnosis, Differential; Edema; Eosinophilia; Follow-Up Studies; Histamine H1 Antagonists; Histamine H2 Antagonists; Humans; Hypersensitivity, Immediate; Male; Rheumatic Diseases; Rheumatic Nodule

1997
Possible role of histamine (H1- and H2-) receptors in the regulation of meningeal blood flow.
    British journal of pharmacology, 2002, Volume: 137, Issue:6

    Topics: Animals; Blood Flow Velocity; Cetirizine; Cimetidine; Dose-Response Relationship, Drug; Dura Mater; Histamine; Histamine H1 Antagonists, Non-Sedating; Histamine H2 Antagonists; Injections, Intravenous; Laser-Doppler Flowmetry; Male; Meningeal Arteries; Rats; Rats, Wistar; Receptors, Histamine H1; Receptors, Histamine H2

2002
Evaluation of the efficacy of antihistamines using human monocyte-derived dendritic cells stimulated with histamine.
    Journal of the American Academy of Dermatology, 2003, Volume: 49, Issue:2

    Topics: Adolescent; Adult; Antigens, CD; B7-2 Antigen; Cetirizine; Chronic Disease; Cimetidine; Dendritic Cells; Female; Flow Cytometry; Histamine; Histamine H1 Antagonists, Non-Sedating; Histamine H2 Antagonists; Humans; Interleukin-8; Male; Membrane Glycoproteins; Monocytes; Urticaria

2003
Transport characteristics of zolmitriptan in a human intestinal epithelial cell line Caco-2.
    The Journal of pharmacy and pharmacology, 2007, Volume: 59, Issue:5

    Topics: Aspirin; Atenolol; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Availability; Biological Transport; Caco-2 Cells; Cetirizine; Cimetidine; Diffusion; Dose-Response Relationship, Drug; Drug Interactions; Flunarizine; Humans; Hydrogen-Ion Concentration; Intestinal Absorption; Intestinal Mucosa; Oxazolidinones; Permeability; Propranolol; Serotonin Receptor Agonists; Sodium-Hydrogen Exchangers; Tryptamines

2007