Page last updated: 2024-09-03

cercosporamide and benzofurans

cercosporamide has been researched along with benzofurans in 23 studies

Compound Research Comparison

Studies (cercosporamide)	Trials (cercosporamide)	Recent Studies (post-2010) (cercosporamide)	Studies (benzofurans)	Trials (benzofurans)	Recent Studies (post-2010) (benzofurans)
26	0	20	13,293	451	4,970

Research

Studies (23)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	1 (4.35)	18.2507
2000's	3 (13.04)	29.6817
2010's	15 (65.22)	24.3611
2020's	4 (17.39)	2.80

Authors

Authors	Studies
Brown, NH; DiDomenico, B; Hare, RS; Hong, Z; Mann, P; Shaw, KJ; Tran, LE	1
Belvo, MD; Campbell, RM; Carpenter, JW; Chio, LC; Fischl, A; Heidler, S; Huss, K; Kulanthaivel, P; Ma, D; Park, TS; Scott, JE; Shaw, M; Shih, C; Strege, MA; Sussman, A; Swartling, JR; Ye, XS; Yeh, WK; Zhu, G	1
Arif, AM; Grange, AH; Grant, DM; Harper, JK; Hess, WM; Hoffman, AM; Kelley-Swift, EG; Mayer, SG; Sovocool, GW; Strobel, GA	1
Araki, K; Arita, T; Furukawa, A; Kuroha, M; Ohsumi, J; Satoh, S	1
Barbieri, LR; Hoshan, L; Leighton, MM; McDonald, LA; Roll, DM; Singh, MP; Urbance, SE	1
Araki, K; Arita, T; Furukawa, A; Hayashi, S; Kuroha, M; Matsui, Y; Ohsumi, J; Satoh, S; Wakabayashi, K	1
Dowless, MS; Dumstorf, CA; Ellis, KE; Furic, L; Graff, JR; Iversen, PW; Konicek, BW; McCann, DJ; McNulty, AM; Parsons, S; Peery, RB; Pelletier, J; Robichaud, N; Sonenberg, N; Stancato, LF; Stephens, JR; Yingling, JM	1
Araki, K; Furukawa, A; Hayashi, S; Inaba, T; Kanda, S; Kuroha, M; Matsui, Y; Matsumoto, T; Ogata, T; Ohsumi, J; Okuyama, R; Tanaka, J; Tanaka, N; Wakabayashi, K; Wakimoto, S	1
Kubicek, CP; Lin, FC; Su, ZZ; Wang, JY; Wang, LW; Xu, BG; Zhang, CL	1
Araki, K; Arita, T; Fukuzaki, T; Furukawa, A; Hayashi, S; Honda, T; Matsui, Y; Mori, M; Ohsumi, J; Satoh, S; Wakabayashi, K	1
Araki, K; Arita, T; Fukuzaki, T; Furukawa, A; Hayashi, S; Honda, T; Kuroha, M; Matsui, Y; Mori, M; Nakamura, K; Ohsumi, J; Satoh, S; Suzuki, O; Tanaka, J; Wakabayashi, K; Wakimoto, S	1
Altman, JK; Glaser, H; Graff, JR; Iversen, PW; Konicek, BW; Kroczynska, B; Platanias, LC; Sassano, A; Szilard, A; Vakana, E	1
Bazin, MA; Bodero, L; Marchand, P; Roussakis, C; Rousseau, B; Tomasoni, C	1
Cao, R; Fragkouli, A; Giannakas, N; Gkogkas, CG; Graff, JR; Jafarnejad, SM; Kaminari, A; Khoutorsky, A; Konicek, BW; Lacaille, JC; Nader, K; Prager-Khoutorsky, M; Price, TJ; Sonenberg, N; Tzinia, AK	1
Guo, S; Liu, Y; Su, X; Sun, L	1
Kim, HJ; Kim, W; Kong, SY; Lee, HR	1
Bach, S; Baratte, B; Bazin, MA; Dao, VH; Grovel, O; Jacquot, C; Le Pape, P; Marchand, P; Ourliac-Garnier, I; Ruchaud, S	1
Aguilar-Valles, A; Cao, R; Comai, S; De Gregorio, D; Eslamizade, MJ; Gobbi, G; Haji, N; Lacaille, JC; Luheshi, G; Matta-Camacho, E; Mechawar, N; Nadon, R; Nuñez, N; Popic, J; Rummel, C; Sharma, V; Sonenberg, N; Tanti, A; Turecki, G; Wiebe, S	1
Chen, F; Gao, J; Shen, J; Wang, L; Wang, Y; Xu, L; Zhang, C	1
Shaji, D	1
den Hertog, J; Hoeksma, J; Ten Dijke, P; van der Zon, GCM	1
Chen, S; Cui, L; Hu, Q; Jiang, Y; Shen, Y; Zhao, J	1
Li, M; Wang, C; Yang, X; Zhu, Y	1

Other Studies

23 other study(ies) available for cercosporamide and benzofurans

Article	Year
Cloning and characterization of KNR4, a yeast gene involved in (1,3)-beta-glucan synthesis. Molecular and cellular biology, 1994, Volume: 14, Issue:2 Topics: Amino Acid Sequence; Base Sequence; Benzofurans; beta-Glucans; Blotting, Western; Chromosomes, Fungal; Cloning, Molecular; DNA, Fungal; Drug Resistance, Microbial; Fungal Proteins; Genes, Fungal; Glucans; Glucosyltransferases; Hydrolases; Killer Factors, Yeast; Kinetics; Membrane Proteins; Molecular Sequence Data; Molecular Weight; Open Reading Frames; Pichia; Protein Biosynthesis; Proteins; Recombinant Proteins; Restriction Mapping; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Schizosaccharomyces pombe Proteins; Sequence Homology, Amino Acid; Transcription Factors	1994
Discovery of cercosporamide, a known antifungal natural product, as a selective Pkc1 kinase inhibitor through high-throughput screening. Eukaryotic cell, 2004, Volume: 3, Issue:4 Topics: Amphotericin B; Animals; Antifungal Agents; Benzofurans; beta-Glucans; Biological Assay; Candida albicans; Drug Synergism; Enzyme Activation; Fungal Proteins; Gene Expression Regulation, Fungal; Glucosyltransferases; Humans; Isoenzymes; Microbial Sensitivity Tests; Molecular Structure; Phosphatidylserines; Protein Kinase C; Protein Kinase Inhibitors	2004
Purification, identification and activity of phomodione, a furandione from an endophytic Phoma species. Phytochemistry, 2008, Volume: 69, Issue:4 Topics: Actinidiaceae; Ascomycota; Basidiomycota; Benzofurans; Crystallography, X-Ray; Magnetic Resonance Spectroscopy; Mass Spectrometry; Microbial Sensitivity Tests; Microscopy, Electron, Scanning; Molecular Structure; Oomycetes; Staphylococcus	2008
(-)-Cercosporamide derivatives as novel antihyperglycemic agents. Bioorganic & medicinal chemistry letters, 2009, Feb-01, Volume: 19, Issue:3 Topics: Animals; Antifungal Agents; Benzofurans; Blood Glucose; Body Weight; Chemistry, Pharmaceutical; Drug Design; Eating; Feeding Behavior; Humans; Hypoglycemic Agents; Inhibitory Concentration 50; Mice; Mice, Transgenic; Models, Chemical	2009
Fermentative production of self-toxic fungal secondary metabolites. Journal of industrial microbiology & biotechnology, 2010, Volume: 37, Issue:4 Topics: Antifungal Agents; Benzofurans; Culture Media; Fermentation; Fungi; Ion Exchange Resins; Microbial Sensitivity Tests; Polystyrenes	2010
Discovery of a novel selective PPARgamma modulator from (-)-Cercosporamide derivatives. Bioorganic & medicinal chemistry letters, 2010, Apr-01, Volume: 20, Issue:7 Topics: Animals; Benzofurans; Crystallography, X-Ray; Diabetes Mellitus; Glucose; Humans; Hyperglycemia; Hypoglycemic Agents; Male; Mice; Models, Molecular; PPAR gamma	2010
Therapeutic inhibition of MAP kinase interacting kinase blocks eukaryotic initiation factor 4E phosphorylation and suppresses outgrowth of experimental lung metastases. Cancer research, 2011, Mar-01, Volume: 71, Issue:5 Topics: Animals; Antineoplastic Agents; Apoptosis; Base Sequence; Benzofurans; Blotting, Western; Cell Proliferation; Eukaryotic Initiation Factor-4E; Female; Humans; Inhibitory Concentration 50; Intracellular Signaling Peptides and Proteins; Lung Neoplasms; Mice; Mice, Nude; Molecular Sequence Data; Neoplasm Metastasis; Phosphorylation; Polymerase Chain Reaction; Protein Serine-Threonine Kinases; Xenograft Model Antitumor Assays	2011
Pharmacology and in vitro profiling of a novel peroxisome proliferator-activated receptor γ ligand, Cerco-A. Biological & pharmaceutical bulletin, 2011, Volume: 34, Issue:7 Topics: Adipocytes; Animals; Base Sequence; Benzofurans; Cell Differentiation; Cell Line, Tumor; DNA Primers; Fluorescence Polarization; Humans; Ligands; Molecular Structure; PPAR gamma; Rats; Rats, Zucker	2011
Bioactive metabolites from Phoma species, an endophytic fungus from the Chinese medicinal plant Arisaema erubescens. Applied microbiology and biotechnology, 2012, Volume: 93, Issue:3 Topics: Anti-Bacterial Agents; Antifungal Agents; Antineoplastic Agents; Arisaema; Ascomycota; Benzofurans; Cell Line, Tumor; Culture Media, Conditioned; Endophytes; Fungi; HL-60 Cells; HT29 Cells; Humans; Medicine, Chinese Traditional; Plant Diseases; Sitosterols; Species Specificity; Tetralones; Trichodermin; Xanthomonas	2012
Substituents at the naphthalene C3 position of (-)-Cercosporamide derivatives significantly affect the maximal efficacy as PPARγ partial agonists. Bioorganic & medicinal chemistry letters, 2012, Feb-01, Volume: 22, Issue:3 Topics: Benzofurans; Crystallography, X-Ray; Gene Expression Regulation; Humans; Hypoglycemic Agents; Inhibitory Concentration 50; Models, Molecular; Molecular Structure; Naphthalenes; PPAR gamma	2012
Synthesis and biological evaluation of novel (-)-Cercosporamide derivatives as potent selective PPARγ modulators. European journal of medicinal chemistry, 2012, Volume: 54 Topics: Animals; Benzofurans; Cell Line, Tumor; Chemistry Techniques, Synthetic; Diabetes Mellitus, Type 2; Female; Genes, Reporter; Humans; Hypoglycemic Agents; Models, Molecular; PPAR gamma; Protein Conformation; Rats	2012
Inhibition of Mnk kinase activity by cercosporamide and suppressive effects on acute myeloid leukemia precursors. Blood, 2013, May-02, Volume: 121, Issue:18 Topics: Adenosine Triphosphatases; Animals; Antineoplastic Agents; Benzofurans; Cation Transport Proteins; Cell Line, Tumor; Cell Proliferation; Copper-Transporting ATPases; Down-Regulation; Humans; K562 Cells; Leukemia, Myeloid, Acute; Mice; Neoplastic Stem Cells; Protein Kinase Inhibitors; U937 Cells; Xenograft Model Antitumor Assays	2013
Synthesis and antiproliferative activity of benzofuran-based analogs of cercosporamide against non-small cell lung cancer cell lines. European journal of medicinal chemistry, 2013, Volume: 69 Topics: Antineoplastic Agents; Benzofurans; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; Lung Neoplasms; Molecular Structure; Structure-Activity Relationship	2013
Pharmacogenetic inhibition of eIF4E-dependent Mmp9 mRNA translation reverses fragile X syndrome-like phenotypes. Cell reports, 2014, Dec-11, Volume: 9, Issue:5 Topics: Adenosine Triphosphatases; Animals; Autistic Disorder; Benzofurans; Brain; Cation Transport Proteins; Cells, Cultured; Copper-Transporting ATPases; Dendritic Spines; Enzyme Induction; Eukaryotic Initiation Factor-4E; Female; Fragile X Syndrome; Humans; Male; Matrix Metalloproteinase 9; Mice, Inbred C57BL; Mice, Transgenic; Phenotype; Phosphorylation; Protein Biosynthesis; Protein Processing, Post-Translational; Receptors, Metabotropic Glutamate	2014
Inhibition of eukaryotic initiation factor 4E phosphorylation by cercosporamide selectively suppresses angiogenesis, growth and survival of human hepatocellular carcinoma. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2016, Volume: 84 Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Benzofurans; Carcinoma, Hepatocellular; Cell Proliferation; Cell Survival; Cisplatin; Dose-Response Relationship, Drug; Drug Synergism; Eukaryotic Initiation Factor-4E; Hep G2 Cells; Humans; Intracellular Signaling Peptides and Proteins; Liver Neoplasms; Mice, SCID; Neovascularization, Pathologic; Phosphorylation; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Signal Transduction; Time Factors; Transfection; Xenograft Model Antitumor Assays	2016
The histone demethylase KDM5A is required for the repression of astrocytogenesis and regulated by the translational machinery in neural progenitor cells. FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2018, Volume: 32, Issue:2 Topics: Animals; Astrocytes; Benzofurans; Cell Differentiation; Gene Expression Regulation, Enzymologic; Glial Fibrillary Acidic Protein; Histones; Methylation; Neural Stem Cells; Promoter Regions, Genetic; Rats; Rats, Sprague-Dawley; Retinoblastoma-Binding Protein 2	2018
Benzofuro[3,2-d]pyrimidines inspired from cercosporamide CaPkc1 inhibitor: Synthesis and evaluation of fluconazole susceptibility restoration. Bioorganic & medicinal chemistry letters, 2018, 07-15, Volume: 28, Issue:13 Topics: Antifungal Agents; Ascomycota; Benzofurans; Biofilms; Candida albicans; Drug Resistance, Fungal; Drug Synergism; Fluconazole; HeLa Cells; Humans; Protein Kinase C; Protein Kinase Inhibitors; Pyrimidinones	2018
Translational control of depression-like behavior via phosphorylation of eukaryotic translation initiation factor 4E. Nature communications, 2018, 06-25, Volume: 9, Issue:1 Topics: Animals; Antidepressive Agents; Anxiety; Behavior, Animal; Benzofurans; Citalopram; Depression; Depressive Disorder, Major; Eukaryotic Initiation Factor-4E; Female; Fluoxetine; Inflammation; Ketamine; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; NF-KappaB Inhibitor alpha; Phosphorylation; Protein Biosynthesis; Protein Serine-Threonine Kinases; Serotonin and Noradrenaline Reuptake Inhibitors; Synaptic Transmission; Tumor Necrosis Factor-alpha	2018
A metabolite of endophytic fungus Cadophora orchidicola from Kalimeris indica serves as a potential fungicide and TLR4 agonist. Journal of applied microbiology, 2019, Volume: 126, Issue:5 Topics: Animals; Antifungal Agents; Ascomycota; Aster Plant; Benzofurans; Cytokines; Female; HEK293 Cells; Humans; Mice; Phylogeny; RAW 264.7 Cells; Toll-Like Receptor 4	2019
Identification of Inhibitors Based on Molecular Docking: Thyroid Hormone Transmembrane Transporter MCT8 as a Target. Current drug discovery technologies, 2021, Volume: 18, Issue:1 Topics: Benzofurans; Biological Transport; Drug Discovery; Emodin; Humans; Mental Retardation, X-Linked; Molecular Docking Simulation; Monocarboxylic Acid Transporters; Muscle Hypotonia; Muscular Atrophy; Mutation; Phytochemicals; Protein Kinase Inhibitors; Resveratrol; Symporters; Thyroid Hormones	2021
Cercosporamide inhibits bone morphogenetic protein receptor type I kinase activity in zebrafish. Disease models & mechanisms, 2020, 09-24, Volume: 13, Issue:9 Topics: Animals; Benzofurans; Biological Assay; Bone Morphogenetic Protein Receptors, Type I; Bone Morphogenetic Proteins; Embryo, Nonmammalian; HEK293 Cells; Hep G2 Cells; Humans; Protein Kinase Inhibitors; Signal Transduction; Time Factors; Zebrafish; Zebrafish Proteins	2020
Preclinical evidence that MNK/eIF4E inhibition by cercosporamide enhances the response to antiangiogenic TKI and mTOR inhibitor in renal cell carcinoma. Biochemical and biophysical research communications, 2020, 09-10, Volume: 530, Issue:1 Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Benzofurans; Carcinoma, Renal Cell; Cell Line, Tumor; Drug Synergism; Eukaryotic Initiation Factor-4E; Humans; Intracellular Signaling Peptides and Proteins; Kidney Neoplasms; Mice, SCID; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Sirolimus; Sunitinib; TOR Serine-Threonine Kinases	2020
Targeting of MNK/eIF4E overcomes chemoresistance in cervical cancer. The Journal of pharmacy and pharmacology, 2021, Sep-07, Volume: 73, Issue:10 Topics: Animals; Antineoplastic Agents; Benzofurans; Cell Line, Tumor; Drug Resistance, Neoplasm; Eukaryotic Initiation Factor-4E; Female; Humans; Intracellular Signaling Peptides and Proteins; Mice, Nude; Molecular Targeted Therapy; Protein Serine-Threonine Kinases; Uterine Cervical Neoplasms; Xenograft Model Antitumor Assays	2021