cepharanthine has been researched along with tetrandrine in 14 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (28.57) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 7 (50.00) | 24.3611 |
| 2020's | 3 (21.43) | 2.80 |
| Authors | Studies |
|---|---|
| Angerhofer, CK; Cordell, GA; Guinaudeau, H; Pezzuto, JM; Wongpanich, V | 1 |
| Cardellina Ii, JH; Currens, MJ; Klausmeyer, P; McCloud, TG; Scudiero, DA; Shoemaker, RH | 1 |
| Batista-Gonzalez, A; Brunhofer, G; Fallarero, A; Gopi Mohan, C; Karlsson, D; Shinde, P; Vuorela, P | 1 |
| Capuzzi, SJ; Fisher, EG; García-Sastre, A; He, S; Li, H; Martínez-Romero, C; Muratov, EN; Qiu, X; Shinn, P; Sun, W; Tawa, G; Tropsha, A; Xu, M; Zheng, W; Zhu, W | 1 |
| Chen, S; Hirano, T; Wang, X; Wu, H; Xu, W; Yamada, H | 1 |
| Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M | 1 |
| Hashimoto, Y; Hojo, H; Imai, Y; Kondo, Y; Nozoe, S | 1 |
| Fujii, T; Hashizume, T; Sato, T; Yamaguchi, H | 1 |
| Hojo, H; Kondo, Y; Takano, F | 1 |
| Haginaka, J; Hirose, I; Kitabatake, T; Matsunaga, H; Moaddel, R | 1 |
| Hirano, T; Masaki, H; Onda, K; Sugiyama, K; Tanaka, S; Tu, Y; Wang, X; Xu, W; Yamada, H | 1 |
| Chen, CL; Chen, ML; Gou, JM; Liu, XN; Meng, XL | 1 |
| Jang, MS; Jin, YH; Kim, DE; Kim, HR; Kim, S; Kwon, S; Lee, JY; Min, JS; Shin, YS; Song, JH | 1 |
| Chen, S; Hirano, T; Onda, K; Sugiyama, K; Tanaka, S; Wang, X; Xu, W; Yamada, H | 1 |
1 review(s) available for cepharanthine and tetrandrine
| Article | Year |
|---|---|
Molecular mechanisms and therapeutic implications of tetrandrine and cepharanthine in T cell acute lymphoblastic leukemia and autoimmune diseases.
Topics: Animals; Antineoplastic Agents; Apoptosis; Autoimmune Diseases; Benzylisoquinolines; Cell Cycle; Down-Regulation; Drug Therapy, Combination; Glucocorticoids; Humans; Mitogen-Activated Protein Kinases; NF-kappa B; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma; Signal Transduction; T-Lymphocytes; TOR Serine-Threonine Kinases | 2021 |
13 other study(ies) available for cepharanthine and tetrandrine
| Article | Year |
|---|---|
Antiplasmodial and cytotoxic activity of natural bisbenzylisoquinoline alkaloids.
Topics: Alkaloids; Animals; Antimalarials; Antineoplastic Agents, Phytogenic; Drug Screening Assays, Antitumor; Humans; Molecular Structure; Plasmodium falciparum; Structure-Activity Relationship; Tumor Cells, Cultured | 1999 |
Discovery and preliminary SAR of bisbenzylisoquinoline alkaloids as inducers of C/EBPα.
Topics: Antineoplastic Agents; Benzylisoquinolines; CCAAT-Enhancer-Binding Protein-alpha; Cell Proliferation; Dose-Response Relationship, Drug; Drug Discovery; Drug Screening Assays, Antitumor; Fruit; Hernandiaceae; High-Throughput Screening Assays; Humans; Molecular Structure; Plant Extracts; Stereoisomerism; Structure-Activity Relationship; U937 Cells | 2012 |
Exploration of natural compounds as sources of new bifunctional scaffolds targeting cholinesterases and beta amyloid aggregation: the case of chelerythrine.
Topics: Acetylcholinesterase; Amyloid beta-Peptides; Benzophenanthridines; Binding Sites; Butyrylcholinesterase; Catalytic Domain; Cholinesterase Inhibitors; Humans; Isoquinolines; Kinetics; Molecular Docking Simulation; Structure-Activity Relationship | 2012 |
Computer-Aided Discovery and Characterization of Novel Ebola Virus Inhibitors.
Topics: Animals; Antiviral Agents; Chlorocebus aethiops; Drug Discovery; Drug Evaluation, Preclinical; Ebolavirus; HeLa Cells; Humans; Molecular Structure; Quantitative Structure-Activity Relationship; Small Molecule Libraries; Vero Cells; Virus Internalization | 2018 |
Bisbenzylisoquinoline alkaloids and P-glycoprotein function: A structure activity relationship study.
Topics: Alkaloids; ATP Binding Cassette Transporter, Subfamily B; Benzylisoquinolines; Cell Line, Tumor; Drug Resistance, Neoplasm; Humans; Molecular Conformation; Structure-Activity Relationship | 2020 |
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology.
Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries | 2023 |
Selective inhibition of T-cell-dependent immune responses by bisbenzylisoquinoline alkaloids in vivo.
Topics: Alkaloids; Animals; Antibody Formation; Benzylisoquinolines; Hypersensitivity, Delayed; Immune Tolerance; Isoquinolines; Lymphocyte Activation; Male; Mice; T-Lymphocytes | 1992 |
Suppressive effect of biscoclaurine alkaloids on agonist-induced activation of phospholipase A2 in rabbit platelets.
Topics: Alkaloids; Animals; Benzylisoquinolines; Blood Platelets; Calcium; Collagen; Dose-Response Relationship, Drug; Enzyme Activation; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Phospholipases A; Phospholipases A2; Platelet Aggregation Inhibitors; Rabbits; Signal Transduction | 1991 |
Inhibitory effect of bisbenzylisoquinoline alkaloids on nitric oxide production in activated macrophages.
Topics: Alkaloids; Amino Acid Oxidoreductases; Animals; Anti-Inflammatory Agents, Non-Steroidal; Benzylisoquinolines; Isoquinolines; Lipopolysaccharides; Macrophages; Male; Mice; Mice, Inbred C3H; Nitric Oxide; Nitric Oxide Synthase; Structure-Activity Relationship | 1993 |
Interaction of cepharanthine with immobilized heat shock protein 90α (Hsp90α) and screening of Hsp90α inhibitors.
Topics: Alkaloids; Benzylisoquinolines; Chromatography, Affinity; HSP90 Heat-Shock Proteins; Humans; Immobilized Proteins; Isoquinolines; Kinetics; Protein Binding; Recombinant Proteins | 2013 |
Tetrandrine and cepharanthine induce apoptosis through caspase cascade regulation, cell cycle arrest, MAPK activation and PI3K/Akt/mTOR signal modification in glucocorticoid resistant human leukemia Jurkat T cells.
Topics: Apoptosis; Benzylisoquinolines; Caspases; Cell Cycle Checkpoints; Gene Expression Regulation; Glucocorticoids; Humans; Jurkat Cells; MAP Kinase Signaling System; Phosphatidylinositol 3-Kinases; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma; Proto-Oncogene Proteins c-akt; Signal Transduction; TOR Serine-Threonine Kinases | 2019 |
Cepharanthine, a bisbenzylisoquinoline alkaloid, inhibits lipopolysaccharide-induced microglial activation.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Benzylisoquinolines; Interleukin-1beta; Interleukin-6; Lipopolysaccharides; Mice; Microglia; Nitric Oxide; Nitric Oxide Synthase Type II; Primary Cell Culture; Tumor Necrosis Factor-alpha | 2019 |
Natural Bis-Benzylisoquinoline Alkaloids-Tetrandrine, Fangchinoline, and Cepharanthine, Inhibit Human Coronavirus OC43 Infection of MRC-5 Human Lung Cells.
Topics: Antiviral Agents; Benzylisoquinolines; Cell Line; Coronavirus Infections; Coronavirus OC43, Human; Cytokines; Humans; Plant Extracts; Stephania tetrandra | 2019 |