Page last updated: 2024-08-17

cephalothin and probenecid

cephalothin has been researched along with probenecid in 24 studies

Research

Studies (24)

TimeframeStudies, this research(%)All Research%
pre-199017 (70.83)18.7374
1990's1 (4.17)18.2507
2000's3 (12.50)29.6817
2010's3 (12.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Nezu, JI; Ohashi, R; Oku, A; Sai, Y; Shimane, M; Tamai, I; Tsuji, A; Yabuuchi, H1
Lombardo, F; Obach, RS; Waters, NJ1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Gozalbes, R; Pineda-Lucena, A1
Bommareddy, A; Gionfriddo, MR; Heindel, GA; Mukhija, P; Vanwert, AL; Witkowski, S; Wolman, AT1
Hook, JB; Kuo, CH1
Barza, M; Bergeron, MG; Brusch, J; Kemmotsu, O; Weinstein, L1
Darrell, JH; Spiers, AS; Tattersall, MH1
Holmes, KK; Karney, WW; Turck, M1
Gaya, H; Hutchinson, RM; Spiers, AS; Tattersall, MH1
Kaplan, K; Reisberg, BE; Weinstein, L1
Clarke, JT; Kirby, WM; Libke, RD; Regamey, C1
Connaughton, B; Limongelli, WA; Williams, AC1
Fukuda, H; Shichijo, K; Yamada, T1
Beaty, HN; Petersdorf, RG; Turck, M1
Caldwell, JL1
Hunter, FE; Irwin, C; O'Brien, JK; Stein, RL; Townsend-Parchman, JK1
Browning, MC; Tune, BM1
Anzai, N; Babu, E; Endou, H; Enomoto, A; Huang, XL; Khamdang, S; Narikawa, S; Noshiro, R; Onozato, ML; Piyachaturawat, P; Takeda, M; Tojo, A1
KUNIN, CM1
EICKHOFF, TC; FINLAND, M; KLEIN, JO; TILLES, JG1
Goldberg, AD; Goodwin, CS; Martin, CM; Raftery, EB; Skeggs, H; Till, AE1

Trials

1 trial(s) available for cephalothin and probenecid

ArticleYear
Effects of rate of infusion and probenecid on serum levels, renal excretion, and tolerance of intravenous doses of cefoxitin in humans: comparison with cephalothin.
    Antimicrobial agents and chemotherapy, 1974, Volume: 6, Issue:3

    Topics: Adult; Anti-Bacterial Agents; Cefoxitin; Cephalothin; Cross-Over Studies; Drug Interactions; Humans; Kidney; Male; Microbial Sensitivity Tests; Probenecid

1974

Other Studies

23 other study(ies) available for cephalothin and probenecid

ArticleYear
Na(+)-dependent carnitine transport by organic cation transporter (OCTN2): its pharmacological and toxicological relevance.
    The Journal of pharmacology and experimental therapeutics, 1999, Volume: 291, Issue:2

    Topics: Biological Transport, Active; Carnitine; Carrier Proteins; Cations; Cells, Cultured; Dose-Response Relationship, Drug; Embryo, Mammalian; Humans; Hydrogen-Ion Concentration; Kidney; Membrane Proteins; Organic Cation Transport Proteins; Sodium; Solute Carrier Family 22 Member 5; Stereoisomerism

1999
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
QSAR-based solubility model for drug-like compounds.
    Bioorganic & medicinal chemistry, 2010, Oct-01, Volume: 18, Issue:19

    Topics: Databases, Factual; Models, Molecular; Pharmaceutical Preparations; Quantitative Structure-Activity Relationship; Solubility; Water

2010
Organic anion transporter 3 interacts selectively with lipophilic β-lactam antibiotics.
    Drug metabolism and disposition: the biological fate of chemicals, 2013, Volume: 41, Issue:4

    Topics: Animals; Anti-Bacterial Agents; beta-Lactams; Biological Transport; Cell Line, Transformed; Humans; Mice; Organic Anion Transport Protein 1; Organic Anion Transporters, Sodium-Independent; Solubility; Structure-Activity Relationship

2013
Specificity of gentamicin accumulation by rat renal cortex.
    Life sciences, 1979, Sep-03, Volume: 25, Issue:10

    Topics: Aminoglycosides; Animals; Biological Transport; Cephaloridine; Cephalothin; Gentamicins; Kidney Cortex; Male; Probenecid; Rats; Structure-Activity Relationship

1979
Extraction of antibiotics from the circulation by liver and kidney: effect of probenecid.
    The Journal of infectious diseases, 1975, Volume: 131 Suppl

    Topics: Animals; Anti-Bacterial Agents; Bile; Biological Assay; Blood Flow Velocity; Cephalothin; Chromium Radioisotopes; Dogs; Kidney; Liver; Lymph; Nafcillin; Penicillin G; Portal Vein; Probenecid; Staphylococcus

1975
Initial therapy with combination of five antibiotics in febrile patients with leukaemia and neutropenia.
    Lancet (London, England), 1972, Jan-22, Volume: 1, Issue:7743

    Topics: Administration, Oral; Agranulocytosis; Anemia, Aplastic; Anti-Bacterial Agents; Bacterial Infections; Carbenicillin; Cephalothin; Clindamycin; Drug Combinations; Drug Hypersensitivity; Escherichia coli Infections; Fever; Gentamicins; Humans; Injections, Intravenous; Kanamycin; Klebsiella Infections; Leukemia; Leukocyte Count; Lymphoma; Methicillin; Penicillin G; Penicillin Resistance; Polymyxins; Probenecid; Pseudomonas Infections; Staphylococcal Infections

1972
Cefazolin in the treatment of gonorrhea.
    The Journal of infectious diseases, 1973, Volume: 128

    Topics: Cephaloridine; Cephalosporins; Cephalothin; Drug Evaluation; Drug Resistance, Microbial; Drug Therapy, Combination; Female; Gonorrhea; Humans; Male; Microbial Sensitivity Tests; Neisseria gonorrhoeae; Probenecid; Sulfides; Tetrazoles; Thiadiazoles

1973
Empirical antibiotic therapy in febrile patients with neutropenia and malignant disease.
    European journal of cancer, 1973, Volume: 9, Issue:6

    Topics: Agranulocytosis; Anti-Bacterial Agents; Bacterial Infections; Carbenicillin; Cephalothin; Clindamycin; Clostridium perfringens; Drug Therapy, Combination; Escherichia coli; Fever; Gentamicins; Humans; Injections, Intravenous; Neoplasms; Neutropenia; Polymyxins; Potassium; Probenecid; Pseudomonas; Staphylococcus

1973
Cephaloridine: antimicrobial activity and pharmacologic behavior.
    The American journal of the medical sciences, 1967, Volume: 253, Issue:6

    Topics: Adult; Alcaligenes; Cephaloridine; Cephalosporins; Cephalothin; Drug Synergism; Enterobacteriaceae; Enterococcus faecalis; Escherichia coli; Haemophilus influenzae; Humans; Klebsiella; Methicillin; Penicillin G; Probenecid; Proteus; Pseudomonas aeruginosa; Salmonella; Staphylococcus; Streptococcus; Streptococcus pneumoniae; Streptococcus pyogenes; Tetracycline

1967
Pharmacokinetics of parenteral sodium cephalexin in comparison with cephalothin and cefazolin.
    Infection, 1974, Volume: 2, Issue:3

    Topics: Adult; Cephalexin; Cephalosporins; Cephalothin; Half-Life; Humans; Injections, Intramuscular; Injections, Intravenous; Kinetics; Male; Probenecid; Sulfides; Tetrazoles; Thiadiazoles

1974
Suppurative osteomyelitis of the mandible secondary to fracture. Report of a case.
    Oral surgery, oral medicine, and oral pathology, 1974, Volume: 38, Issue:6

    Topics: Adult; Bacitracin; Carbenicillin; Cephalothin; Escherichia coli; Female; Fracture Fixation; Fractures, Ununited; Humans; Mandibular Diseases; Mandibular Fractures; Osteomyelitis; Penicillin Resistance; Penicillins; Probenecid; Radiography; Staphylococcus; Suppuration; Therapeutic Irrigation

1974
Effects of synthetic penicillin and cephalosporin on thyroxine-plasma protein interaction in the rat.
    Archives internationales de pharmacodynamie et de therapie, 1969, Volume: 182, Issue:1

    Topics: Animals; Cephaloridine; Cephalosporins; Cephalothin; Cloxacillin; Iodine Isotopes; Liver; Male; Methicillin; Oxacillin; Penicillin V; Penicillins; Probenecid; Protein Binding; Rats; Thyroid Gland; Thyroidectomy; Thyroxine; Thyroxine-Binding Proteins

1969
Activity of broad-spectrum antibiotics against enterococci and their efficacy in enterococcal endocarditis.
    Annals of the New York Academy of Sciences, 1967, Sep-27, Volume: 145, Issue:2

    Topics: Administration, Oral; Ampicillin; Cephaloridine; Cephalothin; Chloramphenicol; Endocarditis, Bacterial; Humans; Injections, Intramuscular; Injections, Intravenous; Male; Microbial Sensitivity Tests; Penicillin G; Probenecid; Streptococcus; Streptomycin; Tetracycline; Time Factors

1967
Actinomycosis treated with cephalothin.
    Southern medical journal, 1971, Volume: 64, Issue:8

    Topics: Actinomycosis, Cervicofacial; Adult; Cephalothin; Female; Humans; Hydrocortisone; Infusions, Parenteral; Nystatin; Penicillins; Prednisone; Probenecid; Sulfisoxazole

1971
Probenecid as an aid to penicillin therapy.
    The Medical letter on drugs and therapeutics, 1966, Feb-11, Volume: 8, Issue:3

    Topics: Aminosalicylic Acids; Cephalothin; Cloxacillin; Erythromycin; Humans; Methicillin; Penicillin G; Penicillin G Benzathine; Probenecid; Sulfonamides

1966
Extension of the blood half-life of glyceryl trinitrate. Inhibition of glutathione organic nitrate ester reductase activity in the rat and guinea pig.
    Biochemical pharmacology, 1980, Jun-15, Volume: 29, Issue:12

    Topics: Animals; Cephalothin; Female; Glutathione Transferase; Guinea Pigs; Half-Life; In Vitro Techniques; Kinetics; Liver; Nitroglycerin; Penicillin G; Probenecid

1980
Reactivity and binding of beta-lactam antibiotics in rabbit renal cortex.
    The Journal of pharmacology and experimental therapeutics, 1983, Volume: 226, Issue:3

    Topics: Animals; Anti-Bacterial Agents; Cephaloglycin; Cephalothin; Female; Kidney Cortex; Kinetics; Microsomes; Penicillin G; Probenecid; Rabbits; Subcellular Fractions

1983
Interaction of human and rat organic anion transporter 2 with various cephalosporin antibiotics.
    European journal of pharmacology, 2003, Mar-28, Volume: 465, Issue:1-2

    Topics: Animals; Anti-Bacterial Agents; Biological Transport; Cefadroxil; Cefamandole; Cefazolin; Cefoperazone; Cefotaxime; Ceftriaxone; Cell Line; Cell Survival; Cephaloridine; Cephalosporins; Cephalothin; Dinoprost; Dose-Response Relationship, Drug; Humans; Kinetics; Mice; Mice, Transgenic; Organic Anion Transporters, Sodium-Independent; Probenecid; Rats; Transfection; Uricosuric Agents

2003
ENHANCEMENT OF ANTIMICROBIAL ACTIVITY OF PENICILLINS AND OTHER ANTIBIOTICS IN HUMAN SERUM BY COMPETITIVE SERUM BINDING INHIBITORS.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1964, Volume: 117

    Topics: Anti-Bacterial Agents; Anti-Infective Agents; Antibiotics, Antitubercular; Antipyrine; Cephalothin; Humans; Methicillin; Naphthalenes; Oxacillin; Penicillamine; Penicillin G; Penicillin V; Penicillins; Pharmacology; Probenecid; Salicylates; Staphylococcus; Sulfonamides

1964
CEPHALOTHIN: ACTIVITY IN VITRO, ABSORPTION AND EXCRETION IN NORMAL SUBJECTS AND CLINICAL OBSERVATIONS IN 40 PATIENTS.
    The American journal of the medical sciences, 1964, Volume: 248

    Topics: Absorption; Anti-Bacterial Agents; Biomedical Research; Blood; Cephalothin; Chemical Phenomena; Chemistry; Drug Therapy; Fluids and Secretions; Geriatrics; In Vitro Techniques; Penicillinase; Penicillins; Pharmacology; Pneumococcal Infections; Probenecid; Staphylococcal Infections; Urine

1964