cephalothin has been researched along with cefuroxime in 91 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 26 (28.57) | 18.7374 |
| 1990's | 6 (6.59) | 18.2507 |
| 2000's | 40 (43.96) | 29.6817 |
| 2010's | 19 (20.88) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Loch, R; Schröter, G | 2 |
| George, WL; Lewis, RP; Meyer, RD | 1 |
| Braveny, I; Dickert, H; Machka, K | 1 |
| Durosoir, JL; Saliou, P; Thabaut, A | 2 |
| Dahl, O; Midtvedt, T; Skar, AG | 1 |
| Kreter, B; Woods, M | 1 |
| Branger, T; Cornelissen, JJ; de Graeff, A; Dekker, AW; Rozenberg-Arska, M; Verdonck, LF; Verhoef, J | 1 |
| Murray, BE; Pickering, LK; Reves, RR; Singh, KV | 1 |
| Shelton, MM; Welch, DF | 1 |
| Gahrn-Hansen, B; Hansen-Nord, M; Siboni, K | 1 |
| Sørensen, TS | 1 |
| Boelaert, J; Piot, P; Van Landuyt, HW; Verbist, L | 1 |
| Concia, E; Marino, P; Marone, P; Verani, D | 1 |
| Iegri, F; Lorenzi, A; Mascellino, MT; Prignano, G | 1 |
| Garcia-Rodriguez, JA | 1 |
| Bianchi, P; Frongillo, RF | 1 |
| Delia, S; Iegri, F; Mascellino, MT; Prignano, G | 1 |
| Forsgren, A | 1 |
| Benonisen, E; Dibb, WL; Digranes, A | 1 |
| Harkness, JL; Mutton, KJ | 1 |
| Barry, AL; Jones, RN; Thornsberry, C | 1 |
| Actor, P; Bowie, BA; Mehta, RJ; Nash, CH; Newman, DJ | 1 |
| De Bac, C; Mascellino, MT; Nuti, M | 1 |
| Weinstein, AJ | 1 |
| Rogers, DT; Russell, AD | 1 |
| Rohn, V | 1 |
| Hattori, H; Kato, M; Nomura, M; Wagai, N; Yamaguchi, F | 1 |
| Samaranayake, LP; Sedgley, CM | 1 |
| Adediran, SA; Kumar, S; Nukaga, M; Pratt, RF | 1 |
| Cho, HS; Giske, CG; Lee, K; Sundman, K; Toleman, MA; Walsh, TR; Yong, D | 1 |
| Verbist, L; Verhaegen, J | 1 |
| Corey, GR; Fowler, VG; Murray, BE; Nannini, EC; Rude, TH; Singh, KV; Stryjewski, ME | 1 |
| Bland, CM; Bookstaver, DA; Mansell, KB; Woodberry, MW | 1 |
| Balada-Llasat, JM; Bauer, KA; Bremmer, DN; Goff, DA | 1 |
| Anderson, WF; Chruszcz, M; Kuhn, ML; Majorek, KA; Minor, W | 1 |
| Brandsch, M; Luckner, P | 1 |
| Biegel, A; Brandsch, M; Gebauer, S; Hartrodt, B; Neubert, K; Thondorf, I | 1 |
| Cattoir, V; Nordmann, P; Poirel, L; Soares, A; Soussy, CJ | 1 |
| Bonnet, R; Chanal, C; Delmas, J; Lesens, O; Robin, F; Schweitzer, C; Tournilhac, O | 1 |
| Aubert, D; Naas, T; Nordmann, P; Ozcan, A | 1 |
| Arlet, G; Loli, A; Miriagou, V; Papagiannitsis, CC; Tzelepi, E; Tzouvelekis, LS | 1 |
| Caniça, M; Ferreira, E; Leitão, J; Manageiro, V; Mendonça, N | 1 |
| Cattoir, V; Corvec, S; Drugeon, H; Faccone, D; Galas, M; Mugnier, P; Nordmann, P; Pasteran, F; Petroni, A; Poirel, L; Rapoport, M | 1 |
| Ayala, JA; Casellas, JM; Di Conza, J; Ghiglione, B; Gutkind, G; Power, P; Radice, M; Rodríguez, MM | 1 |
| Beceiro, A; Bou, G; Canle, D; Fernández, A; Lasa, I; Latasa, C; Mallo, S; Molina, F; Pérez, A; Pérez, S; Poza, M; Tomás, Mdel M; Villanueva, R | 1 |
| Miriagou, V; Papagiannitsis, CC; Tzelepi, E; Tzouvelekis, LS | 1 |
| Bonnet, R; Brebion, A; Constantin, JM; Delmas, J; Dubois, D; Robin, F | 1 |
| Girlich, D; Leclercq, R; Naas, T; Nordmann, P | 1 |
| Bonnet, R; Neuwirth, C; Robin, F; Siebor, E | 1 |
| Iredell, JR; Partridge, SR; Zong, Z | 1 |
| Courvalin, P; Decré, D; Høiby, EA; Meziane-Cherif, D; Périchon, B | 1 |
| Courvalin, P; Dupêchez, M; Galimand, M; Lambert, T; Meziane-Cherif, D | 1 |
| Bonnet, R; Caniça, M; Ferreira, E; Manageiro, V; Mendonça, N; Robin, F; Salgado, MJ | 1 |
| Bonnet, R; Caniça, M; Manageiro, V; Mendonça, N | 1 |
| Limansky, AS; Marchiaro, P; Mussi, MA; Pasteran, F; Tomatis, PE; Viale, AM; Vila, AJ | 1 |
| Doi, Y; Nordmann, P; Paterson, DL; Poirel, L | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Docquier, JD; Frère, JM; Rossolini, GM; Stoczko, M | 1 |
| Andersson, DI; Negrea, A; Pränting, M; Rhen, M | 1 |
| Castanheira, M; Samuelsen, Ø; Spencer, J; Walsh, TR | 1 |
| Jarlier, V; Mayer, C; Petrella, S; Renard, M; Sougakoff, W; Ziental-Gelus, N | 1 |
| Albertí, S; Beceiro, A; Bou, G; Garau, M; Gutiérrez, O; Juan, C; Oliver, A; Pérez, JL | 1 |
| Arpin, C; Bezian, MC; Coulange, L; Demarthe, F; Dubois, V; Minarini, LA; Nordmann, P; Poirel, L; Quentin, C | 1 |
| González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M | 1 |
| Beceiro, A; Bou, G; Cisneros, JM; Fernández-Cuenca, F; Martínez-Martínez, L; Pachón, J; Pascual, A; Pérez, A; Rodríguez-Baño, J; Vila, J | 1 |
| Nordmann, P; Plésiat, P; Poirel, L; Rodriguez-Martinez, JM | 1 |
| Kotsakis, SD; Miriagou, V; Tzelepi, E; Tzouvelekis, LS; Whichard, JM; Zioga, A | 1 |
| Bonnet, R; Brisabois, A; Cloeckaert, A; Doublet, B; Fabre, L; Granier, SA; Robin, F; Weill, FX | 1 |
| Chanteperdrix, V; Croizé, J; Nordmann, P; Poirel, L; Potron, A | 1 |
| Kotsakis, SD; Miriagou, V; Papagiannitsis, CC; Tzelepi, E; Tzouvelekis, LS | 1 |
| Ghori, S; Griggs, DJ; Johnson, MM; Mott, A; Peake, L; Piddock, LJ | 1 |
| De Luca, F; Delmarcelle, M; Docquier, JD; Dubus, A; Frère, JM; Nacoulma, OG; Rossolini, GM; Simporé, J; Zeba, B | 1 |
| Distèche-Nguyen, M; Gerards, T; Luxen, A; Miguet, L; Pasha, FA; Thomas, A; Zervosen, A | 1 |
| Girlich, D; Nordmann, P; Poirel, L | 2 |
| Bonnet, R; Casin, I; Doublet, B; Fabre, L; Le Fleche, A; Robin, F; Weill, FX | 1 |
| De Luca, F; Docquier, JD; Ide, L; Nordmann, P; Poirel, L; Rossolini, GM; Verlinde, A | 1 |
| Aggoune-Khinache, N; Bonnet, R; Delmas, J; Naim, M; Robin, F | 1 |
| Kotsakis, SD; Legakis, NJ; Miriagou, V; Papagiannitsis, CC; Tzelepi, E; Tzouvelekis, LS | 1 |
| De Luca, F; Docquier, JD; Fosse, T; Giraud-Morin, C; Rossolini, GM | 1 |
| Eb, F; Guillon, H; Mammeri, H | 1 |
| Bini, L; Bonomo, RA; Borgianni, L; Docquier, JD; Frère, JM; Matagne, A; Rossolini, GM; Vandenameele, J | 1 |
| Nordmann, P; Poirel, L; Rodríguez-Martínez, JM; Ronco, E | 1 |
| Collins, B; Cotter, PD; Curtis, N; Hill, C; Ross, RP | 1 |
| Borgianni, L; Docquier, JD; Hanson, ND; Prandi, S; Rossolini, GM; Salden, L; Santella, G | 1 |
| Aldini, G; De Luca, L; Marconi, C; Pedretti, A; Regazzoni, L; Vistoli, G | 1 |
| Anderson, KC; Kellogg, GE; Sarkar, A | 1 |
| Bommareddy, A; Gionfriddo, MR; Heindel, GA; Mukhija, P; Vanwert, AL; Witkowski, S; Wolman, AT | 1 |
2 review(s) available for cephalothin and cefuroxime
| Article | Year |
|---|---|
Antibiotic prophylaxis for cardiothoracic operations. Meta-analysis of thirty years of clinical trials.
Topics: Anti-Bacterial Agents; Cardiac Surgical Procedures; Cefamandole; Cefazolin; Ceftriaxone; Cefuroxime; Cephalosporins; Cephalothin; Cephradine; Clinical Trials as Topic; Humans; MEDLINE; Meta-Analysis as Topic; Penicillins; Postoperative Period; Premedication; Prospective Studies; Randomized Controlled Trials as Topic; Surgical Wound Infection; Thoracic Surgery | 1992 |
The cephalosporins: activity and clinical use.
Topics: Cefaclor; Cefamandole; Cefatrizine; Cefazolin; Cefoxitin; Cefuroxime; Cephacetrile; Cephalexin; Cephaloglycin; Cephaloridine; Cephalosporins; Cephalothin; Cephapirin; Drug Hypersensitivity; Humans; Kidney Diseases | 1980 |
1 trial(s) available for cephalothin and cefuroxime
| Article | Year |
|---|---|
Imipenem versus gentamicin combined with either cefuroxime or cephalothin as initial therapy for febrile neutropenic patients.
Topics: Adult; Aged; Cefuroxime; Cephalothin; Drug Therapy, Combination; Female; Gentamicins; Humans; Imipenem; Injections, Intravenous; Male; Middle Aged; Neutropenia; Prospective Studies; Random Allocation | 1992 |
88 other study(ies) available for cephalothin and cefuroxime
| Article | Year |
|---|---|
[Comparison of four recently introduced cephalosporins with respect to probability of resistance in multiresistant strains of Escherichia coli, Proteus mirabilis and Klebsiella spec. (author's transl)].
Topics: Anti-Bacterial Agents; Cefaclor; Cefamandole; Cefoxitin; Cefuroxime; Cephalosporins; Cephalothin; Drug Resistance, Microbial; Escherichia coli; Klebsiella; Proteus mirabilis; Species Specificity | 1979 |
[The distribution of minimal inhibitory concentrations of recently introduced cephalosporins in multiresistant strains of Escherichia coli, Proteus mirabilis and Klebsiella spec. as revealed by zone sizes of a standardized agar diffusion test (author's tr
Topics: Cefaclor; Cefamandole; Cefoxitin; Cefuroxime; Cephalosporins; Cephalothin; Drug Resistance, Microbial; Escherichia coli; Klebsiella; Microbial Sensitivity Tests; Proteus mirabilis | 1979 |
Susceptibility of cephalothin-resistant gram-negative bacilli to piperacillin, cefuroxime, and other selected antibiotics.
Topics: Amikacin; Anti-Bacterial Agents; Carbenicillin; Cefamandole; Cefoxitin; Cefuroxime; Cephalosporins; Cephalothin; Enterobacter; Enterobacteriaceae; Escherichia coli; Klebsiella; Penicillin Resistance; Piperacillin; Proteus; Pseudomonas aeruginosa; Serratia | 1978 |
[Antibacterial activity of cefotaxim in comparison with seven cephalosporins].
Topics: Bacteria; Cefaclor; Cefamandole; Cefazolin; Cefoxitin; Cefuroxime; Cephalexin; Cephalosporins; Cephalothin; Enterobacteriaceae; Escherichia coli; Humans; In Vitro Techniques; Pseudomonas | 1979 |
["In vitro" activity of cefamandole, cefalotin, cefoxitin and cefuroxim against enterobacteria and Staphylococcus aureus isolated in hospital (author's transl)].
Topics: Cefamandole; Cefoxitin; Cefuroxime; Cephalosporins; Cephalothin; Enterobacteriaceae; Hospitals; Microbial Sensitivity Tests; Oxacillin; Penicillin Resistance; Staphylococcus aureus | 1979 |
A comparison of the in vitro activity of a new cephalosporin, cefuroxime, and cephalothin against 810 clinical isolates.
Topics: Bacteria; Cefuroxime; Cephalosporins; Cephalothin; Enterobacter; Escherichia coli; Klebsiella; Microbial Sensitivity Tests; Proteus; Staphylococcus; Streptococcus | 1979 |
Comparative in vitro activities of amoxicillin-clavulanic acid, cefuroxime, cephalexin, and cephalothin against trimethoprim-resistant Escherichia coli isolated from stools of children attending day-care centers.
Topics: Amoxicillin; Amoxicillin-Potassium Clavulanate Combination; Anti-Bacterial Agents; Cefuroxime; Cephalexin; Cephalothin; Child Day Care Centers; Child, Preschool; Clavulanic Acids; Drug Therapy, Combination; Escherichia coli; Feces; Humans; Infant; Microbial Sensitivity Tests; Plasmids; Trimethoprim Resistance | 1990 |
Antimicrobial activities and susceptibility testing considerations of ampicillin, cephalothin, cefaclor, and cefuroxime against invasive isolates of Haemophilus influenzae.
Topics: Ampicillin; Anti-Bacterial Agents; Cefaclor; Cefuroxime; Cephalothin; Haemophilus influenzae; Humans; Microbial Sensitivity Tests; Penicillin Resistance | 1989 |
Studies on clinical isolates of coagulase-negative staphylococci resistant to methicillin. Evidence of cross-resistance between methicillin and cephalothin.
Topics: Anti-Bacterial Agents; Cefuroxime; Cephalosporins; Cephalothin; Coagulase; Drug Resistance, Microbial; Humans; Methicillin; Staphylococcal Infections; Staphylococcus | 1988 |
Comparative in vitro activity of four beta-lactam antibiotics in surgical wound fluid against staphylococci.
Topics: Anti-Bacterial Agents; Cefuroxime; Cephalothin; Culture Media; Dicloxacillin; Hip Fractures; Humans; Methicillin; Staphylococcal Infections; Staphylococcus; Staphylococcus aureus; Surgical Wound Infection | 1985 |
In vitro activity of temocillin against clinical isolates.
Topics: Bacteria; Cefotaxime; Cefuroxime; Cephalothin; Gram-Positive Bacteria; In Vitro Techniques; Microbial Sensitivity Tests; Moxalactam; Penicillins | 1985 |
[Microbiological evaluation of the antibacterial activity of cefotaxime in comparison with other cephalosporins].
Topics: Bacteria; Cefazolin; Cefoperazone; Cefotaxime; Cefoxitin; Cefuroxime; Cephacetrile; Cephalexin; Cephaloridine; Cephalosporins; Cephalothin; Cephradine; Enterobacter; Escherichia coli; Humans; Klebsiella pneumoniae; Salmonella; Staphylococcus aureus | 1982 |
[Minimal inhibitory and bactericidal concentrations of cefoperazone, cefotaxime, cefuroxime and cefalotin against 90 bacterial strains].
Topics: Acinetobacter; Bacteria; Cefoperazone; Cefotaxime; Cefoxitin; Cefuroxime; Cephalosporins; Cephalothin; Drug Resistance, Microbial; Enterobacteriaceae; Humans; Microbial Sensitivity Tests; Pseudomonas aeruginosa; Streptococcus | 1982 |
Activities of cefoperazone, cefotaxime, cefuroxime, and cephalothin against 128 clinical isolates.
Topics: Cefoperazone; Cefotaxime; Cefuroxime; Cephalosporins; Cephalothin; Enterobacteriaceae; Microbial Sensitivity Tests; Pseudomonas aeruginosa; Staphylococcus aureus | 1980 |
A comparison of the activity in vitro of different cephalosporins: cephalothin, cephradine, cephacetrile, cefaclor, cefuroxime and cefotaxime.
Topics: Cefaclor; Cefotaxime; Cefuroxime; Cephacetrile; Cephalosporins; Cephalothin; Cephradine; Enterobacter; Microbial Sensitivity Tests; Pseudomonas aeruginosa | 1980 |
Comparative in vitro activity of 8 cephalosporins on 109 strains of Neisseria gonorrhoeae and 60 strains of Neisseria meningitidis.
Topics: Cefamandole; Cefoperazone; Cefotaxime; Cefoxitin; Ceftriaxone; Cefuroxime; Cephalosporins; Cephalothin; Cephamycins; Dose-Response Relationship, Drug; Microbial Sensitivity Tests; Moxalactam; Neisseria gonorrhoeae; Neisseria meningitidis | 1981 |
[Study of the minimum inhibiting concentration of a new cephalosporin (HR 756): comparative data with other beta-lactamic antibiotics].
Topics: Bacteria; Cefamandole; Cefotaxime; Cefoxitin; Cefuroxime; Cephalothin | 1981 |
Comparative in vitro activity of first, second and third generation cephalosporins.
Topics: Bacteria; Cefamandole; Cefoperazone; Cefotaxime; Cefoxitin; Ceftazidime; Cefuroxime; Cephalosporins; Cephalothin; Cephamycins; Dose-Response Relationship, Drug; Moxalactam; Structure-Activity Relationship | 1981 |
Ceftazidime: in vitro comparison with cephalothin, cefuroxime, and netilmicin. A Norwegian study.
Topics: Anti-Bacterial Agents; Bacteria; Ceftazidime; Cefuroxime; Cephalosporins; Cephalothin; Drug Evaluation; Gentamicins; Microbial Sensitivity Tests; Netilmicin; Norway | 1984 |
Antibacterial activity of five cephalosporins.
Topics: Bacteria; Cefamandole; Cefuroxime; Cephalosporins; Cephalothin; Enterobacteriaceae; In Vitro Techniques; Microbial Sensitivity Tests; Pseudomonas aeruginosa; Staphylococcus | 1981 |
Cefuroxime, cefamandole, cefoxitin, and cephalothin in vitro susceptibility tests: reassessment of the "class representative" concept, confirmation of disk interpretive criteria, and proposed quality control guidelines.
Topics: Bacteria; Cefamandole; Cefoxitin; Cefuroxime; Cephalosporins; Cephalothin; Drug Resistance, Microbial; Humans; Microbial Sensitivity Tests; Quality Control; Reagent Kits, Diagnostic; Regression Analysis | 1983 |
Cefuroxime inhibition of cephalothin hydrolysis by the constitutive beta-lactamase from E. cloacae P99.
Topics: beta-Lactamase Inhibitors; Cefuroxime; Cephalosporins; Cephalothin; Enterobacter; Enterobacteriaceae; Hydrolysis; Kinetics | 1980 |
[Clinico-microbiologic bases for the use of new cephalosporins].
Topics: Bacteria; Bacteroides; beta-Lactamase Inhibitors; Cefamandole; Cefoxitin; Cefuroxime; Cephalosporins; Cephalothin; Chemical Phenomena; Chemistry; Drug Resistance, Microbial; Enterobacteriaceae; Humans; Peptococcus; Peptostreptococcus; Pseudomonas | 1982 |
Comparative staphylolytic activity of cefoxitin, cephalothin and cefuroxime.
Topics: Cefoxitin; Cefuroxime; Cephalosporins; Cephalothin; Microbial Sensitivity Tests; Staphylococcus aureus | 1980 |
[Evaluation of second generation cephalosporins: cefamandole, cefoxitine, cefuroxime. Reccomendations by working group].
Topics: Cefamandole; Cefoxitin; Cefuroxime; Cephalosporins; Cephalothin; Drug Evaluation; Humans; Microbial Sensitivity Tests | 1980 |
[Personal experience with administration of Zinacef in the form of a "protected coagulum" in patients after heart surgery].
Topics: Adult; Aged; Cardiac Surgical Procedures; Cefuroxime; Cephalothin; Humans; Middle Aged; Premedication | 1995 |
An assessment of antigenic potential of beta-lactam antibiotics, low molecular weight drugs, using guinea pig models.
Topics: Anaphylaxis; Animals; Anti-Bacterial Agents; Antigens; Cefmenoxime; Cefmetazole; Ceftazidime; Cefuroxime; Cephalosporins; Cephalothin; Drug Hypersensitivity; Enzyme-Linked Immunosorbent Assay; Female; Guinea Pigs; Hypersensitivity, Delayed; Intradermal Tests; Passive Cutaneous Anaphylaxis; Piperacillin | 1997 |
Antimicrobial susceptibility of oral isolates of Enterobacter cloacae and Klebsiella pneumoniae from a southern Chinese population.
Topics: Adult; Ampicillin; Anti-Bacterial Agents; Ceftazidime; Cefuroxime; Cephalothin; Child; Ciprofloxacin; Diet, Vegetarian; Drug Resistance, Microbial; Enterobacter cloacae; Gentamicins; Hong Kong; Humans; Klebsiella pneumoniae; Microbial Sensitivity Tests; Mouth; Tetracycline; Trimethoprim, Sulfamethoxazole Drug Combination | 1998 |
Kinetics of turnover of cefotaxime by the Enterobacter cloacae P99 and GCl beta-lactamases: two free enzyme forms of the P99 beta-lactamase detected by a combination of pre- and post-steady state kinetics.
Topics: Acylation; beta-Lactamases; Catalysis; Cefotaxime; Cefuroxime; Cephalothin; Enterobacter cloacae; Hydrolysis; Kinetics; Models, Chemical; Protein Binding; Spectrometry, Fluorescence; Spectrophotometry; Structure-Activity Relationship; Substrate Specificity | 2004 |
Characterization of a new metallo-beta-lactamase gene, bla(NDM-1), and a novel erythromycin esterase gene carried on a unique genetic structure in Klebsiella pneumoniae sequence type 14 from India.
Topics: Amino Acid Sequence; Anti-Bacterial Agents; beta-Lactamases; Carboxylic Ester Hydrolases; Cefotaxime; Cefuroxime; Cephalosporins; Cephalothin; Drug Resistance, Multiple, Bacterial; Electrophoresis, Gel, Pulsed-Field; Humans; India; Kinetics; Klebsiella Infections; Klebsiella pneumoniae; Microbial Sensitivity Tests; Molecular Sequence Data; Penicillins; Sequence Analysis, DNA; Sequence Homology, Amino Acid | 2009 |
Ceftazidime: comparative in-vitro study.
Topics: Anti-Bacterial Agents; Bacteria; Bacterial Infections; Carbenicillin; Cefotaxime; Ceftazidime; Cefuroxime; Cephalosporins; Cephalothin; Gram-Negative Bacteria; Humans; Microbial Sensitivity Tests; Pseudomonas aeruginosa | 1981 |
Determination of an inoculum effect with various cephalosporins among clinical isolates of methicillin-susceptible Staphylococcus aureus.
Topics: Anti-Bacterial Agents; Ceftriaxone; Cefuroxime; Cephalexin; Cephalosporins; Cephalothin; Humans; Methicillin; Microbial Sensitivity Tests; Staphylococcal Infections; Staphylococcus aureus | 2010 |
Correlation of cefpodoxime susceptibility with cephalothin and cefuroxime for urinary tract isolates.
Topics: Anti-Bacterial Agents; Bacteria; Cefpodoxime; Ceftizoxime; Cefuroxime; Cephalothin; Drug Resistance, Bacterial; Humans; Microbial Sensitivity Tests; Urinary Tract Infections | 2014 |
Ceftriaxone Etest non-susceptible methicillin susceptible Staphylococcus aureus time-kill responses.
Topics: Anti-Bacterial Agents; Bacteremia; Cefepime; Ceftaroline; Ceftriaxone; Cefuroxime; Cephalosporins; Cephalothin; Disk Diffusion Antimicrobial Tests; Humans; Oxacillin; Staphylococcus aureus | 2017 |
Structural, functional, and inhibition studies of a Gcn5-related N-acetyltransferase (GNAT) superfamily protein PA4794: a new C-terminal lysine protein acetyltransferase from pseudomonas aeruginosa.
Topics: Acetyl Coenzyme A; Acetyltransferases; Anti-Bacterial Agents; Bacterial Proteins; Binding Sites; Cephalosporins; Crystallography, X-Ray; Enzyme Inhibitors; Lysine; Protein Structure, Tertiary; Pseudomonas aeruginosa | 2013 |
Interaction of 31 beta-lactam antibiotics with the H+/peptide symporter PEPT2: analysis of affinity constants and comparison with PEPT1.
Topics: Animals; Anti-Bacterial Agents; beta-Lactams; Binding Sites; Caco-2 Cells; Dose-Response Relationship, Drug; Humans; Peptide Transporter 1; Protein Binding; Rats; Symporters | 2005 |
Three-dimensional quantitative structure-activity relationship analyses of beta-lactam antibiotics and tripeptides as substrates of the mammalian H+/peptide cotransporter PEPT1.
Topics: Animals; beta-Lactams; Cell Line, Tumor; Dipeptides; Drug Design; Humans; Mammals; Models, Molecular; Oligopeptides; Peptide Transporter 1; Quantitative Structure-Activity Relationship; Substrate Specificity; Symporters | 2005 |
Novel Ambler class A beta-lactamase LAP-1 and its association with the plasmid-mediated quinolone resistance determinant QnrS1.
Topics: Amino Acid Sequence; Bacterial Proteins; beta-Lactam Resistance; beta-Lactamases; Cloning, Molecular; Enterobacter cloacae; Gene Expression Regulation, Bacterial; Gene Expression Regulation, Enzymologic; Molecular Sequence Data; Plasmids; Quinolones; Sequence Alignment | 2007 |
Evolution of TEM-type enzymes: biochemical and genetic characterization of two new complex mutant TEM enzymes, TEM-151 and TEM-152, from a single patient.
Topics: beta-Lactamases; Drug Resistance, Bacterial; Escherichia coli; Evolution, Molecular; Humans; Microbial Sensitivity Tests; Molecular Sequence Data; Mutation | 2007 |
Chromosome-encoded narrow-spectrum Ambler class A beta-lactamase GIL-1 from Citrobacter gillenii.
Topics: beta-Lactamases; Chromosomes; Chromosomes, Bacterial; Citrobacter; Cloning, Molecular; DNA, Bacterial; Escherichia coli; Gene Expression Regulation, Bacterial; Gene Expression Regulation, Enzymologic; Genes, Bacterial; Molecular Sequence Data | 2007 |
SCO-1, a novel plasmid-mediated class A beta-lactamase with carbenicillinase characteristics from Escherichia coli.
Topics: Amino Acid Sequence; Anti-Bacterial Agents; beta-Lactam Resistance; beta-Lactamases; beta-Lactams; Escherichia coli; Humans; Microbial Sensitivity Tests; Molecular Sequence Data; Penicillinase; Plasmids; Sequence Analysis, DNA | 2007 |
Spread of extended-spectrum beta-lactamase CTX-M-producing escherichia coli clinical isolates in community and nosocomial environments in Portugal.
Topics: Aged; Anti-Bacterial Agents; beta-Lactamases; Community-Acquired Infections; Cross Infection; Drug Resistance, Bacterial; Escherichia coli; Escherichia coli Infections; Escherichia coli Proteins; Humans; Microbial Sensitivity Tests; Middle Aged; Portugal | 2007 |
Identification of the novel narrow-spectrum beta-lactamase SCO-1 in Acinetobacter spp. from Argentina.
Topics: Acinetobacter; Acinetobacter Infections; Amino Acid Sequence; Anti-Bacterial Agents; Argentina; beta-Lactam Resistance; beta-Lactamases; beta-Lactams; Clavulanic Acid; Cloning, Molecular; Humans; Microbial Sensitivity Tests; Molecular Sequence Data; Sequence Analysis, DNA | 2007 |
Biochemical characterization of PER-2 and genetic environment of blaPER-2.
Topics: Amino Acid Sequence; Base Sequence; beta-Lactam Resistance; beta-Lactamases; Catalysis; Citrobacter freundii; Conjugation, Genetic; DNA, Bacterial; DNA, Recombinant; Enterobacteriaceae; Genes, Bacterial; Humans; Hydrolysis; Isoelectric Focusing; Kinetics; Mass Spectrometry; Microbial Sensitivity Tests; Molecular Sequence Data; Molecular Weight; Plasmids; Polymerase Chain Reaction; Promoter Regions, Genetic; Protein Conformation; Protein Sorting Signals; Sequence Analysis, DNA | 2007 |
Cloning, nucleotide sequencing, and analysis of the AcrAB-TolC efflux pump of Enterobacter cloacae and determination of its involvement in antibiotic resistance in a clinical isolate.
Topics: Bacterial Proteins; Base Sequence; beta-Lactamases; Carrier Proteins; Cloning, Molecular; DNA, Bacterial; Drug Resistance, Bacterial; Enterobacter cloacae; Enterobacteriaceae Infections; Genes, MDR; Genetic Vectors; Humans; Microbial Sensitivity Tests; Molecular Sequence Data; Plasmids; Porins | 2007 |
Plasmid-encoded ACC-4, an extended-spectrum cephalosporinase variant from Escherichia coli.
Topics: Anti-Bacterial Agents; Cephalosporinase; Culture Media; DNA Primers; Drug Resistance, Bacterial; Escherichia coli; Kinetics; Models, Molecular; Molecular Sequence Data; Plasmids; Reverse Transcriptase Polymerase Chain Reaction; Spectrophotometry, Ultraviolet | 2007 |
TEM-158 (CMT-9), a new member of the CMT-type extended-spectrum beta-lactamases.
Topics: beta-Lactam Resistance; beta-Lactamases; beta-Lactams; Catalysis; Ceftazidime; Clavulanic Acid; Escherichia coli; Escherichia coli Proteins; Isoenzymes; Kinetics; Microbial Sensitivity Tests; Molecular Sequence Data; Sequence Analysis, DNA | 2007 |
Molecular and biochemical characterization of the chromosome-encoded class A beta-lactamase BCL-1 from Bacillus clausii.
Topics: Amino Acid Sequence; Bacillus; Bacterial Proteins; beta-Lactamases; Chromosome Mapping; Chromosomes, Bacterial; Cloning, Molecular; Microbial Sensitivity Tests; Molecular Sequence Data; Molecular Weight; Sequence Homology, Amino Acid; Substrate Specificity | 2007 |
First occurrence of an IMP metallo-beta-lactamase in Aeromonas caviae: IMP-19 in an isolate from France.
Topics: Aeromonas; Anti-Bacterial Agents; beta-Lactamases; beta-Lactams; France; Integrons; Kinetics; Microbial Sensitivity Tests; Molecular Sequence Data; Plasmids; Sequence Analysis, DNA; Substrate Specificity | 2007 |
RmtC 16S rRNA methyltransferase in Australia.
Topics: Aminoglycosides; Anti-Bacterial Agents; Australia; beta-Lactam Resistance; beta-Lactamases; beta-Lactams; Drug Resistance, Bacterial; Genes, rRNA; Humans; Methyltransferases; Microbial Sensitivity Tests; Proteus Infections; Proteus mirabilis; RNA, Ribosomal, 16S | 2008 |
Genetic and biochemical characterization of CAD-1, a chromosomally encoded new class A penicillinase from Carnobacterium divergens.
Topics: Amino Acid Sequence; beta-Lactams; Chromosomes, Bacterial; Cloning, Molecular; Electrophoresis, Gel, Pulsed-Field; Gram-Positive Bacteria; Gram-Positive Bacterial Infections; Humans; Infant, Newborn; Kinetics; Microbial Sensitivity Tests; Molecular Sequence Data; Penicillin Resistance; Penicillinase; Sequence Alignment; Sequence Analysis, DNA; Substrate Specificity | 2008 |
Genetic and biochemical characterization of OXA-63, a new class D beta-lactamase from Brachyspira pilosicoli BM4442.
Topics: Amino Acid Sequence; Anti-Bacterial Agents; Base Sequence; beta-Lactamases; Brachyspira; Cloning, Molecular; Diarrhea; Feces; Gram-Negative Bacterial Infections; Humans; Kinetics; Molecular Sequence Data; Oxacillin; Penicillin Resistance; Sequence Analysis, DNA | 2008 |
The Lys234Arg substitution in the enzyme SHV-72 is a determinant for resistance to clavulanic acid inhibition.
Topics: Amino Acid Substitution; Amoxicillin; Anti-Bacterial Agents; Arginine; Aztreonam; Bacterial Proteins; beta-Lactamase Inhibitors; beta-Lactamases; Cephalosporins; Clavulanic Acid; Computer Simulation; Imipenem; Isoelectric Focusing; Kinetics; Klebsiella pneumoniae; Lysine; Microbial Sensitivity Tests; Models, Molecular; Molecular Sequence Data; Penicillins; Protein Conformation; Protein Structure, Tertiary | 2008 |
Biochemical characterization of SHV-55, an extended-spectrum class A beta-lactamase from Klebsiella pneumoniae.
Topics: Anti-Bacterial Agents; beta-Lactamases; Kinetics; Klebsiella pneumoniae | 2008 |
Biochemical characterization of metallo-beta-lactamase VIM-11 from a Pseudomonas aeruginosa clinical strain.
Topics: beta-Lactam Resistance; beta-Lactamases; beta-Lactams; Binding Sites; Escherichia coli; Humans; Kinetics; Microbial Sensitivity Tests; Models, Molecular; Plasmids; Pseudomonas aeruginosa; Pseudomonas Infections | 2008 |
Characterization of a naturally occurring class D beta-lactamase from Achromobacter xylosoxidans.
Topics: Achromobacter denitrificans; Amino Acid Sequence; Anti-Bacterial Agents; beta-Lactamases; beta-Lactams; Cloning, Molecular; Humans; Kinetics; Microbial Sensitivity Tests; Molecular Sequence Data; Sequence Analysis, DNA | 2008 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Functional diversity among metallo-beta-lactamases: characterization of the CAR-1 enzyme of Erwinia carotovora.
Topics: Amino Acid Sequence; Bacterial Proteins; Base Sequence; beta-Lactamases; Cloning, Molecular; DNA Primers; DNA, Bacterial; Drug Resistance, Bacterial; Genes, Bacterial; Molecular Sequence Data; Open Reading Frames; Pectobacterium carotovorum; Phenotype; Phylogeny; Recombinant Proteins; Sequence Homology, Amino Acid | 2008 |
Mechanism and fitness costs of PR-39 resistance in Salmonella enterica serovar Typhimurium LT2.
Topics: Animals; Anti-Bacterial Agents; Antimicrobial Cationic Peptides; Bacterial Proteins; Cathelicidins; Drug Resistance, Multiple, Bacterial; Female; Genetic Complementation Test; Mice; Mice, Inbred BALB C; Microbial Sensitivity Tests; Models, Genetic; Mutagenesis, Insertional; Mutation; Salmonella Infections, Animal; Salmonella typhimurium; Sequence Deletion | 2008 |
Kinetic characterization of VIM-7, a divergent member of the VIM metallo-beta-lactamase family.
Topics: Acremonium; Bacterial Proteins; beta-Lactamases; Catalysis; Catalytic Domain; Cefepime; Ceftazidime; Cephalosporins; Kinetics; Models, Molecular; Mutation; Penicillinase; Protein Structure, Tertiary; Recombinant Proteins; Structure-Activity Relationship; Substrate Specificity | 2008 |
Genetic and structural insights into the dissemination potential of the extremely broad-spectrum class A beta-lactamase KPC-2 identified in an Escherichia coli strain and an Enterobacter cloacae strain isolated from the same patient in France.
Topics: Aged; Base Sequence; beta-Lactam Resistance; beta-Lactamases; beta-Lactams; Catalytic Domain; Cephalosporin Resistance; Crystallography, X-Ray; DNA Primers; DNA, Bacterial; Enterobacter cloacae; Enterobacteriaceae Infections; Escherichia coli; Escherichia coli Infections; France; Genes, Bacterial; Humans; Imipenem; Kinetics; Male; Models, Molecular; Mutation | 2008 |
Characterization of the new metallo-beta-lactamase VIM-13 and its integron-borne gene from a Pseudomonas aeruginosa clinical isolate in Spain.
Topics: Amino Acid Sequence; Anti-Bacterial Agents; Bacterial Proteins; Base Sequence; beta-Lactam Resistance; beta-Lactamases; Cloning, Molecular; DNA Primers; DNA, Bacterial; Genes, Bacterial; Genetic Variation; Humans; Imipenem; Integrons; Kinetics; Meropenem; Molecular Sequence Data; Phylogeny; Pseudomonas aeruginosa; Pseudomonas Infections; Recombinant Proteins; Sequence Homology, Amino Acid; Spain; Thienamycins | 2008 |
Molecular and biochemical characterization of SHV-56, a novel inhibitor-resistant beta-lactamase from Klebsiella pneumoniae.
Topics: Aged; Amino Acid Substitution; Base Sequence; beta-Lactam Resistance; beta-Lactamases; DNA Primers; DNA, Bacterial; Female; Genes, Bacterial; Humans; Isoelectric Point; Kinetics; Klebsiella Infections; Klebsiella pneumoniae; Molecular Sequence Data; Mutagenesis, Insertional; Recombinant Proteins | 2008 |
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship | 2008 |
Genetic variability among ampC genes from acinetobacter genomic species 3.
Topics: Acinetobacter; Acinetobacter baumannii; Amino Acid Sequence; Ampicillin Resistance; Anti-Bacterial Agents; Bacterial Proteins; beta-Lactam Resistance; Escherichia coli; Genes, Bacterial; Genetic Variation; Humans; Kinetics; Microbial Sensitivity Tests; Models, Molecular; Molecular Sequence Data; Promoter Regions, Genetic; Reverse Transcriptase Polymerase Chain Reaction; Sequence Homology, Amino Acid; Spain | 2009 |
Naturally occurring Class A ss-lactamases from the Burkholderia cepacia complex.
Topics: Alleles; Amino Acid Sequence; Amino Acid Substitution; Base Sequence; beta-Lactamases; Burkholderia cepacia complex; DNA, Bacterial; Drug Resistance, Multiple, Bacterial; Humans; Hydrolysis; Isoelectric Point; Kinetics; Microbial Sensitivity Tests; Molecular Sequence Data; Phylogeny; Plasmids; Sequence Analysis, DNA; Sequence Homology, Amino Acid | 2009 |
CMY-31 and CMY-36 cephalosporinases encoded by ColE1-like plasmids.
Topics: Alleles; Amino Acid Sequence; Amino Acid Substitution; Arginine; Base Sequence; beta-Lactamase Inhibitors; beta-Lactamases; Cephalosporinase; Citrobacter freundii; Cysteine; DNA Transposable Elements; DNA, Bacterial; Escherichia coli; Genes, Bacterial; Glutamine; Humans; Hydrolysis; Inhibitory Concentration 50; Isoelectric Point; Kinetics; Klebsiella pneumoniae; Microbial Sensitivity Tests; Models, Genetic; Models, Molecular; Molecular Sequence Data; Plasmids; Salmonella enterica; Sequence Analysis, DNA; Species Specificity; Substrate Specificity; Transformation, Genetic | 2009 |
Novel plasmid-encoded ceftazidime-hydrolyzing CTX-M-53 extended-spectrum beta-lactamase from Salmonella enterica serotypes Westhampton and Senftenberg.
Topics: Animals; Anti-Bacterial Agents; Bacterial Proteins; beta-Lactamases; Cardiidae; Ceftazidime; Ceftriaxone; Cephalosporin Resistance; Electrophoresis, Gel, Pulsed-Field; France; Microbial Sensitivity Tests; Plasmids; Polymerase Chain Reaction; Salmonella enterica; Serotyping | 2009 |
Genetic and biochemical characterization of the first extended-spectrum CARB-type beta-lactamase, RTG-4, from Acinetobacter baumannii.
Topics: Acinetobacter baumannii; Amino Acid Sequence; Anti-Bacterial Agents; beta-Lactamases; Drug Resistance, Bacterial; Escherichia coli; Kinetics; Microbial Sensitivity Tests; Molecular Sequence Data; Mutagenesis, Site-Directed | 2009 |
Extended-spectrum properties of CMY-30, a Val211Gly mutant of CMY-2 cephalosporinase.
Topics: Aztreonam; beta-Lactamases; beta-Lactams; Ceftazidime; Cephalosporins; Escherichia coli Proteins; Protein Binding; Protein Structure, Secondary | 2009 |
Beta-lactamase-mediated beta-lactam resistance in Campylobacter species: prevalence of Cj0299 (bla OXA-61) and evidence for a novel beta-Lactamase in C. jejuni.
Topics: Amino Acid Sequence; Amoxicillin; Ampicillin; Animals; Anti-Bacterial Agents; Base Sequence; beta-Lactam Resistance; beta-Lactamases; Blotting, Southern; Campylobacter jejuni; Carbenicillin; Cephalosporins; Chickens; Cloxacillin; Isoelectric Focusing; Mass Spectrometry; Microbial Sensitivity Tests; Molecular Sequence Data; Penicillins; Piperacillin; Polymerase Chain Reaction; Sequence Alignment; Ticarcillin | 2009 |
IND-6, a highly divergent IND-type metallo-beta-lactamase from Chryseobacterium indologenes strain 597 isolated in Burkina Faso.
Topics: Adult; Amino Acid Sequence; Anti-Bacterial Agents; beta-Lactamases; Cefepime; Ceftazidime; Cephalexin; Cephalosporins; Cephalothin; Chryseobacterium; Female; Humans; Microbial Sensitivity Tests; Molecular Sequence Data; Phylogeny; Protein Structure, Secondary; Sequence Homology, Amino Acid | 2009 |
Discovery of new inhibitors of resistant Streptococcus pneumoniae penicillin binding protein (PBP) 2x by structure-based virtual screening.
Topics: Computational Biology; Computer Simulation; Drug Discovery; Drug Evaluation, Preclinical; Drug Resistance, Bacterial; Ligands; Penicillin-Binding Proteins; Protein Binding; Streptococcus pneumoniae; Structure-Activity Relationship | 2009 |
First isolation of the blaOXA-23 carbapenemase gene from an environmental Acinetobacter baumannii isolate.
Topics: Acinetobacter baumannii; beta-Lactamases; DNA, Bacterial; Escherichia coli; France; Genes, Bacterial; Water Microbiology | 2010 |
Molecular and biochemical characterization of the natural chromosome-encoded class A beta-lactamase from Pseudomonas luteola.
Topics: Amino Acid Sequence; Anti-Bacterial Agents; beta-Lactamases; Catheters, Indwelling; Chromosomes, Bacterial; Cloning, Molecular; Electrophoresis, Gel, Pulsed-Field; Genes, Bacterial; Genetic Variation; Isoelectric Focusing; Kinetics; Microbial Sensitivity Tests; Molecular Sequence Data; Phylogeny; Plasmids; Pseudomonas; Pseudomonas Infections; Recombinant Proteins; Reverse Transcriptase Polymerase Chain Reaction; Substrate Specificity | 2010 |
BEL-2, an extended-spectrum beta-lactamase with increased activity toward expanded-spectrum cephalosporins in Pseudomonas aeruginosa.
Topics: Belgium; beta-Lactamases; Cephalosporinase; Cephalosporins; Cross Infection; Escherichia coli; Genes, Bacterial; Humans; Kinetics; Microbial Sensitivity Tests; Pseudomonas aeruginosa; Pseudomonas Infections | 2010 |
Novel ambler class A carbapenem-hydrolyzing beta-lactamase from a Pseudomonas fluorescens isolate from the Seine River, Paris, France.
Topics: Amino Acid Sequence; Anti-Bacterial Agents; Bacterial Proteins; beta-Lactamases; Blotting, Southern; Cloning, Molecular; DNA, Bacterial; Drug Resistance, Bacterial; Electrophoresis, Gel, Pulsed-Field; France; Fresh Water; Gram-Negative Bacteria; Health Surveys; Kinetics; Microbial Sensitivity Tests; Molecular Sequence Data; Plasmids; Pseudomonas fluorescens; Water Microbiology | 2010 |
Novel VIM metallo-beta-lactamase variant from clinical isolates of Enterobacteriaceae from Algeria.
Topics: Algeria; Anti-Bacterial Agents; Base Sequence; beta-Lactamases; beta-Lactams; Carbapenems; DNA, Bacterial; Drug Resistance, Bacterial; Enterobacteriaceae; Enterobacteriaceae Infections; Genome, Bacterial; Hospitals, Military; Imipenem; Isoelectric Focusing; Kinetics; Microbial Sensitivity Tests; Molecular Sequence Data; Penicillins; Phenotype | 2010 |
GES-13, a beta-lactamase variant possessing Lys-104 and Asn-170 in Pseudomonas aeruginosa.
Topics: Anti-Bacterial Agents; Aztreonam; beta-Lactamases; beta-Lactams; Cephalosporins; Genetic Variation; Humans; Integrons; Microbial Sensitivity Tests; Molecular Sequence Data; Pseudomonas aeruginosa; Pseudomonas Infections; Sequence Analysis, DNA | 2010 |
Genetic and biochemical characterization of TRU-1, the endogenous class C beta-lactamase from Aeromonas enteropelogenes.
Topics: Aeromonas; Amino Acid Sequence; Base Sequence; beta-Lactamases; Cloning, Molecular; DNA Primers; DNA, Bacterial; Drug Resistance, Bacterial; Escherichia coli; Genes, Bacterial; Humans; Kinetics; Molecular Sequence Data; Phylogeny; Sequence Homology, Amino Acid; Sequence Homology, Nucleic Acid; Transformation, Genetic | 2010 |
Characterization of CSP-1, a novel extended-spectrum beta-lactamase produced by a clinical isolate of Capnocytophaga sputigena.
Topics: Amino Acid Sequence; Amoxicillin; Anti-Bacterial Agents; beta-Lactam Resistance; beta-Lactamases; Capnocytophaga; Cephalosporins; Gram-Negative Bacterial Infections; Humans; Microbial Sensitivity Tests; Molecular Sequence Data; Sepsis | 2010 |
Mutational analysis of VIM-2 reveals an essential determinant for metallo-beta-lactamase stability and folding.
Topics: Ampicillin; Ampicillin Resistance; Anti-Bacterial Agents; beta-Lactamases; DNA Mutational Analysis; Enzyme Stability; Escherichia coli; Kinetics; Microbial Sensitivity Tests; Models, Molecular; Protein Conformation; Protein Folding; Structure-Activity Relationship | 2010 |
Extended-spectrum cephalosporinase in Acinetobacter baumannii.
Topics: Acinetobacter baumannii; Amino Acid Sequence; Amino Acid Substitution; Anti-Bacterial Agents; Aztreonam; Bacterial Proteins; beta-Lactamases; Cefepime; Ceftazidime; Cephalosporin Resistance; Cephalosporinase; Cephalosporins; Humans; Microbial Sensitivity Tests; Molecular Sequence Data; Monobactams; Mutagenesis, Site-Directed | 2010 |
The ABC transporter AnrAB contributes to the innate resistance of Listeria monocytogenes to nisin, bacitracin, and various beta-lactam antibiotics.
Topics: Anti-Bacterial Agents; ATP-Binding Cassette Transporters; Bacitracin; Bacterial Proteins; beta-Lactam Resistance; Listeria monocytogenes; Nisin | 2010 |
Genetic context and biochemical characterization of the IMP-18 metallo-beta-lactamase identified in a Pseudomonas aeruginosa isolate from the United States.
Topics: Amino Acid Sequence; Bacterial Proteins; beta-Lactamases; beta-Lactams; Ertapenem; Meropenem; Microbial Sensitivity Tests; Models, Genetic; Molecular Sequence Data; Open Reading Frames; Pseudomonas aeruginosa; Sequence Homology, Amino Acid; Thienamycins; United States | 2011 |
Fragmental modeling of hPepT2 and analysis of its binding features by docking studies and pharmacophore mapping.
Topics: Binding Sites; Computer Simulation; Drug Design; Humans; Ligands; Models, Molecular; Peptides; Protein Binding; Structural Homology, Protein; Symporters | 2011 |
Computational analysis of structure-based interactions and ligand properties can predict efflux effects on antibiotics.
Topics: Anti-Bacterial Agents; beta-Lactams; Computational Biology; Drug Resistance, Bacterial; Hydrophobic and Hydrophilic Interactions; Ligands; Membrane Transport Proteins; Microbial Sensitivity Tests; Models, Molecular; Protein Binding; Protein Conformation; Quantitative Structure-Activity Relationship; Regression Analysis; Thermodynamics | 2012 |
Organic anion transporter 3 interacts selectively with lipophilic β-lactam antibiotics.
Topics: Animals; Anti-Bacterial Agents; beta-Lactams; Biological Transport; Cell Line, Transformed; Humans; Mice; Organic Anion Transport Protein 1; Organic Anion Transporters, Sodium-Independent; Solubility; Structure-Activity Relationship | 2013 |