Page last updated: 2024-08-24

cephalosporin c and probenecid

cephalosporin c has been researched along with probenecid in 79 studies

Research

Studies (79)

TimeframeStudies, this research(%)All Research%
pre-199063 (79.75)18.7374
1990's11 (13.92)18.2507
2000's4 (5.06)29.6817
2010's1 (1.27)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Avery, GS; Brogden, RN; Heel, RC; Speight, TM1
Neubert, U; Ruckdeschel, G1
Davies, RO; Holmes, GI; Martin, CM; Rogers, D; Schrogie, JJ; Skeggs, H; Yeh, KC1
Berg, SW; Harrison, WO; Kilpatrick, ME; McCutchan, JA1
Bodine, JA; Dacey, RG; Sande, MA; Sherertz, RJ; Strausbaugh, LJ; Zak, O1
Kunst, MW; Mattie, H1
Bint, AJ; Holt, HA; Reeves, DS; Stocks, PJ1
Dean, S; Kendall, MJ; Selen, A; Welling, PG; Wise, R1
Jiang, NX; Ni, SW; Zeng, YL; Zhang, ZL1
Dingeldein, E; Leopold, G; Pabst, J; Ungethüm, W1
Celozzi, E; Miller, AK; Pelak, BA1
Bint, AJ; Holt, HA; Reeves, DS1
Fluker, JL; Price, JD1
Brown, JD; Fowler, W; Rahim, G1
Black, HR; Brier, GL; Griffith, RS; Wolny, JD1
Foord, RD1
Tune, BM1
Hashimoto, S; Matsubayashi, K; Osada, Y; Saito, A; Sakai, O; Shiba, K; Shimada, J; Yoshida, K; Yoshida, M1
Barbhaiya, RH; Pittman, KA; Shukla, UA1
DeSante, KA; Zeckel, ML1
Kokue, EI; Soback, S; Ziv, G1
Baddour, LM; Cocchetto, DM; Gibbs, RS; Mertz, G; Noble, RC1
Brown, MP; Gronwall, R; Houston, AE; Juzwiak, JS1
Das, RP; Jones, K; Robinson, AJ; Timmins, DJ1
Fong, IW; Hinton, NA; Linton, W; Simbul, M1
Ansink-Schipper, MC; Michel, MF; Schift, R; Stolz, E; van Joost, T; van Ulsen, J; Woudstra, RK1
Sakurai, O; Tanaka, H; Yamaoka, K; Yano, Y1
Nakashima, E; Takanosu, K; Tamai, I; Terasaki, T; Tsuji, A1
Gottlieb, A; Mills, J1
Dacey, RG; Sande, MA1
Holmes, KK; Karney, WW; Turck, M1
Reeves, DS; Wise, R1
Duncan, WC1
Platts, WM1
Kaplan, K; Reisberg, BE; Weinstein, L1
Applestein, JM; Crosby, EB; Johnson, WD; Kaye, D1
Clarke, JT; Kirby, WM; Libke, RD; Regamey, C1
Barza, M; Weinstein, L1
Madsen, PO; Naber, KG; Westenfelder, SR1
Willcox, RR1
Holst-Larsen, L1
Celozzi, E; Hendlin, D; Kong, Y; Kropp, H; Miller, AK; Pelak, BA; Stapley, EO1
Rein, MF; Sande, MA; Westervelt, FB1
Barza, M; Bergeron, MG; Brusch, J; Weinstein, L1
Celozzi, E; Hendlin, D; Kong, Y; Miller, AK; Pelak, BA; Stapley, EO1
Fukuda, H; Shichijo, K; Yamada, T1
Davies, JA; Holt, JM1
Holloway, WJ; Taylor, WA1
Sim, SK1
Child, KJ; Dodds, MG1
Brier, GL; DeSante, KA; Hatcher, BL; Israel, KS; Wolny, JD1
Lutz, B1
Kawabata, T; Miyahara, T; Nakamura, M; Shimada, J; Sugeno, K; Ueda, Y; Yamaji, T; Yoshida, T1
Backhaus, A; Meyer-Rohn, J1
Saito, A1
Blumer, JL; Kercsmar, CM; Murdell, D; Myers, CM; Reed, MD; Stern, RC1
Haidl, S; Hoffstedt, B; Walder, M1
Shimizu, K1
Murakawa, T; Nakamoto, S; Nishida, M1
Acred, P; Harding, SM; Harper, PB; Kirby, SM; O'Callaghan, CH; Ryan, DM1
Em, SV; Iakovlev, VP; Klimova, VS; Rudzit, EA1
Jack, DB; Kendall, MJ; Roberts, DH; Welling, PG1
Actor, P; Alexander, F; Dubb, J; Ehrlich, S; Familiar, R; Pitkin, D; Stote, R1
Burch, K; Jovanovich, JF; Pohlod, DJ; Saravolatz, LD1
Freeman, DA; Hanlon, D; Parton, K; Whittem, T1
Nerli, B; Picó, G1
Brown, GR1
Gimeno, MJ; Granero, L; Martínez, M; Peris, JE; Torres-Molina, F1
Garton, AM; Gilpin, J; Marrelli, M; Rennie, RP; Shafran, SD1
Ballard, RC; Crabbé, F; Dangor, Y; Grobbelaar, TM; Laga, M; van Dyck, E1
Nikoskelainen, J; Oksi, J; Viljanen, MK1
Endou, H; Hosoyamada, M; Kanai, Y; Sekine, T; Takeda, M; Tojo, A1
Desai, A; Mopkar, O; Rao, PP1
Athan, E; Chambers, F; Gibson, K; Grayson, ML; McDonald, M; Munckhof, WJ; Paull, P1
Guttendorf, RJ; Kugler, AR; Lepsy, CS; Smith, DE1
Anzai, N; Babu, E; Endou, H; Enomoto, A; Huang, XL; Khamdang, S; Narikawa, S; Noshiro, R; Onozato, ML; Piyachaturawat, P; Takeda, M; Tojo, A1
Kaku, T; Kato, Y; Liu, K; Liu, Q; Meng, Q; Sun, H; Wang, C1

Reviews

4 review(s) available for cephalosporin c and probenecid

ArticleYear
Cefuroxime: a review of its antibacterial activity, pharmacological properties and therapeutic use.
    Drugs, 1979, Volume: 17, Issue:4

    Topics: Adult; Bacteria; Cephalosporins; Child; Drug Resistance, Microbial; Female; Furans; Gonorrhea; Humans; Hydrogen-Ion Concentration; Infant, Newborn; Kinetics; Osteomyelitis; Pregnancy; Probenecid; Respiratory Tract Infections; Sepsis; Surgical Wound Infection; Tissue Distribution; Urinary Tract Infections

1979
Bioavailability and pharmacokinetics of cefoxitin sodium.
    The Journal of antimicrobial chemotherapy, 1978, Volume: 4, Issue:B

    Topics: Absorption; Animals; Biological Availability; Cefoxitin; Cephalosporins; Chemical Phenomena; Chemistry; Drug Interactions; Haplorhini; Humans; Kidney Diseases; Kinetics; Mice; Probenecid; Protein Binding; Rats

1978
Pharmacokinetic profile of loracarbef.
    The American journal of medicine, 1992, Jun-22, Volume: 92, Issue:6A

    Topics: Adult; Age Factors; Biological Availability; Cephalosporins; Child; Clinical Trials as Topic; Food; Humans; Kidney Diseases; Metabolic Clearance Rate; Probenecid

1992
Cephalosporin-probenecid drug interactions.
    Clinical pharmacokinetics, 1993, Volume: 24, Issue:4

    Topics: Cephalosporins; Drug Interactions; Humans; Probenecid

1993

Trials

17 trial(s) available for cephalosporin c and probenecid

ArticleYear
Cefoxitin as a single-dose treatment for urethritis caused by penicillinase-producing Neisseria gonorrhoeae.
    The New England journal of medicine, 1979, Sep-06, Volume: 301, Issue:10

    Topics: beta-Lactamases; Cefoxitin; Cephalosporins; Follow-Up Studies; Gonorrhea; Humans; Male; Neisseria gonorrhoeae; Penicillin G Procaine; Penicillin Resistance; Penicillinase; Probenecid; Urethritis

1979
Cefoxitin sodium: a clinical and pharmacological study.
    The Journal of antimicrobial chemotherapy, 1978, Volume: 4, Issue:B

    Topics: Adult; Aged; Bacterial Infections; Cefoxitin; Cephalosporins; Child; Clinical Trials as Topic; Drug Interactions; Female; Humans; Male; Middle Aged; Probenecid; Time Factors

1978
Probenecid: an unexplained effect on cephalosporin pharmacology.
    British journal of clinical pharmacology, 1979, Volume: 8, Issue:5

    Topics: Adolescent; Adult; Cefaclor; Cephalosporins; Cephradine; Drug Interactions; Female; Humans; Kinetics; Male; Middle Aged; Probenecid; Time Factors

1979
Clinical pharmacology phase I of cefazedone, a new cephalosporin, in healthy volunteers. III. Investigations of the mechanism of renal elimination.
    Arzneimittel-Forschung, 1979, Volume: 29, Issue:2a

    Topics: Adolescent; Adult; Cephalosporins; Humans; Kidney; Kinetics; Male; Models, Biological; Probenecid

1979
The efficacy of cefuroxime for the treatment of acute gonorrhoea in men.
    The British journal of venereal diseases, 1978, Volume: 54, Issue:3

    Topics: Acute Disease; Cephalosporins; Drug Administration Schedule; Drug Therapy, Combination; Furans; Gonorrhea; Humans; Injections, Intramuscular; Male; Probenecid

1978
Clinical comparison of single-oral-dose cefuroxime axetil and amoxicillin with probenecid for uncomplicated gonococcal infections in women.
    Antimicrobial agents and chemotherapy, 1989, Volume: 33, Issue:6

    Topics: Adolescent; Adult; Amoxicillin; Cefuroxime; Cephalosporins; Drug Therapy, Combination; Female; Gonorrhea; Humans; Middle Aged; Probenecid

1989
Cefuroxime axetil to treat gonorrhea.
    Genitourinary medicine, 1988, Volume: 64, Issue:6

    Topics: Ampicillin; Cefuroxime; Cephalosporins; Clinical Trials as Topic; Drug Therapy, Combination; Female; Gonorrhea; Humans; Male; Probenecid; Random Allocation

1988
Comparative clinical efficacy of single oral doses of cefuroxime axetil and amoxicillin in uncomplicated gonococcal infections.
    Antimicrobial agents and chemotherapy, 1986, Volume: 30, Issue:2

    Topics: Amoxicillin; Cefuroxime; Cephalosporins; Drug Therapy, Combination; Female; Gonorrhea; Humans; Male; Neisseria gonorrhoeae; Probenecid; Prospective Studies; Random Allocation

1986
Comparison of oral treatment of uncomplicated urogenital and rectal gonorrhoea with cefuroxime axetil ester or clavulanic acid potentiated amoxycillin (Augmentin).
    Genitourinary medicine, 1986, Volume: 62, Issue:5

    Topics: Administration, Oral; Adolescent; Adult; Amoxicillin; Amoxicillin-Potassium Clavulanate Combination; Cefuroxime; Cephalosporins; Clavulanic Acids; Clinical Trials as Topic; Drug Combinations; Drug Therapy, Combination; Female; Gonorrhea; Humans; Male; Middle Aged; Probenecid; Random Allocation

1986
Cefuroxime axetil for treatment of uncomplicated gonorrhea.
    Antimicrobial agents and chemotherapy, 1986, Volume: 30, Issue:2

    Topics: Adolescent; Adult; Aged; Amoxicillin; Cefuroxime; Cephalosporins; Drug Therapy, Combination; Gonorrhea; Humans; Male; Middle Aged; Probenecid; Random Allocation; Rectal Diseases; Urethritis

1986
Venereal disease: diagnosis and treatment.
    Drugs, 1973, Volume: 5, Issue:2

    Topics: Cephalosporins; Clinical Trials as Topic; Drug Combinations; Erythromycin; Female; Gonorrhea; Humans; Male; Penicillin G Procaine; Penicillins; Probenecid; Sexually Transmitted Diseases; Spectinomycin; Syphilis; Syphilis, Congenital; Tetracycline; Time Factors; Urethritis

1973
Pharmacokinetics of a new cephalosporin, cephacetrile, in patients with normal and impaired renal function.
    Infection, 1973, Volume: 1, Issue:3

    Topics: Acetamides; Cephalosporins; Clinical Trials as Topic; Creatinine; Drug Evaluation; Humans; Injections, Intramuscular; Injections, Intravenous; Inulin; Iodine Radioisotopes; Iothalamic Acid; Kidney; Kidney Diseases; Kidney Function Tests; Kidney Glomerulus; Kidney Tubules; Nitriles; Probenecid; Urinary Tract Infections

1973
The effects on the pharmacokinetics of intravenous ceftiofur sodium in dairy cattle of simultaneous intravenous acetyl salicylate (aspirin) or probenecid.
    Journal of veterinary pharmacology and therapeutics, 1995, Volume: 18, Issue:1

    Topics: Analysis of Variance; Animals; Aspirin; Cattle; Cephalosporins; Cross-Over Studies; Drug Interactions; Female; Half-Life; Injections, Intravenous; Ion Transport; Probenecid; Tissue Distribution

1995
Cefaclor, an alternative to third generation cephalosporins for the treatment of gonococcal urethritis in the developing world?
    Genitourinary medicine, 1997, Volume: 73, Issue:6

    Topics: Administration, Oral; Cefaclor; Cephalosporins; Drug Therapy, Combination; Gonorrhea; Humans; Male; Microbial Sensitivity Tests; Probenecid; South Africa; Treatment Outcome; Urethritis; Uricosuric Agents

1997
Comparison of oral cefixime and intravenous ceftriaxone followed by oral amoxicillin in disseminated Lyme borreliosis.
    European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 1998, Volume: 17, Issue:10

    Topics: Administration, Oral; Adult; Amoxicillin; Cefixime; Cefotaxime; Ceftriaxone; Cephalosporins; Drug Administration Schedule; Drug Therapy, Combination; Humans; Injections, Intravenous; Lyme Disease; Penicillins; Probenecid; Renal Agents; Treatment Outcome

1998
Comparative trial to evaluate the efficacy and tolerability of cefuroxime 250mg with probenecid 250mg with cefuroxime 500mg in the management of community acquired pneumonia, acute bronchitis and acute exacerbation of chronic bronchitis.
    Journal of the Indian Medical Association, 2000, Volume: 98, Issue:10

    Topics: Acute Disease; Adult; Bronchitis; Cefuroxime; Cephalosporins; Community-Acquired Infections; Drug Therapy, Combination; Female; Humans; Male; Pneumonia; Probenecid; Prospective Studies

2000
Once-daily intravenous cefazolin plus oral probenecid is equivalent to once-daily intravenous ceftriaxone plus oral placebo for the treatment of moderate-to-severe cellulitis in adults.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2002, Jun-01, Volume: 34, Issue:11

    Topics: Administration, Oral; Adolescent; Adult; Aged; Aged, 80 and over; Cefazolin; Ceftriaxone; Cellulitis; Cephalosporins; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Injections, Intravenous; Male; Middle Aged; Placebos; Probenecid; Uricosuric Agents

2002

Other Studies

58 other study(ies) available for cephalosporin c and probenecid

ArticleYear
[Isolation of penicillinase forming gonococci in Munich].
    MMW, Munchener medizinische Wochenschrift, 1978, Aug-11, Volume: 120, Issue:32-33

    Topics: Adult; Cephalosporins; Germany, West; Gonorrhea; Humans; Male; Neisseria gonorrhoeae; Penicillin Resistance; Penicillinase; Penicillins; Philippines; Probenecid

1978
Gonorrhea--recommended treatment schecules, 1974.
    American family physician, 1975, Volume: 11, Issue:2

    Topics: Adolescent; Ampicillin; Cephalosporins; Child; Child, Preschool; Drug Therapy, Combination; Erythromycin; Female; Gonorrhea; Humans; Infant; Infant, Newborn; Infant, Newborn, Diseases; Male; Penicillin G Procaine; Pharyngitis; Pregnancy; Pregnancy Complications, Infectious; Probenecid; Salpingitis; Spectinomycin; Sulfides; Tetracycline; Tetrazoles; Thiadiazoles; Urethritis

1975
Factors influencing the penetration of antimicrobial agents into the cerebrospinal fluid of experimental animals.
    Scandinavian journal of infectious diseases. Supplementum, 1978, Issue:14

    Topics: Animals; Cephalosporins; Disease Models, Animal; Meningitis; Penicillins; Probenecid; Protein Binding; Rabbits

1978
Probenecid and the antibacterial activity of cephradine in vivo.
    The Journal of infectious diseases, 1978, Volume: 137, Issue:6

    Topics: Animals; Cephalosporins; Cephradine; Depression, Chemical; Escherichia coli; Male; Mice; Probenecid

1978
[Studies on pharmacokinetics. I. Cefathiamidinum (author's transl)].
    Yao xue xue bao = Acta pharmaceutica Sinica, 1979, Volume: 14, Issue:10

    Topics: Cephalosporins; Drug Interactions; Female; Humans; Male; Probenecid; Time Factors

1979
The enhancement of beta-lactam antibiotic therapy by novobiocin.
    The Journal of antibiotics, 1977, Volume: 30, Issue:11

    Topics: Animals; Cephaloridine; Cephalosporins; Drug Interactions; Female; Mice; Novobiocin; Penicillin G; Probenecid; Salmonella Infections, Animal

1977
Effect of probenecid on serum cefoxitin concentrations.
    The Journal of antimicrobial chemotherapy, 1977, Volume: 3, Issue:6

    Topics: Adult; Cefoxitin; Cephalosporins; Drug Interactions; Female; Half-Life; Humans; Probenecid

1977
Clinical experience in the use of cefuroxime in gonorrhoea.
    The British journal of venereal diseases, 1978, Volume: 54, Issue:6

    Topics: Cephalosporins; Drug Administration Schedule; Drug Therapy, Combination; Female; Furans; Gonorrhea; Humans; Male; Probenecid

1978
Effect of probenecid on the blood levels and urinary excretion of cefamandole.
    Antimicrobial agents and chemotherapy, 1977, Volume: 11, Issue:5

    Topics: Adult; Cephalosporins; Drug Interactions; Humans; Male; Mandelic Acids; Middle Aged; Probenecid; Time Factors

1977
Cefuroxime: human pharmacokinetics..
    Antimicrobial agents and chemotherapy, 1976, Volume: 9, Issue:5

    Topics: Administration, Oral; Adult; Blood Proteins; Cephaloridine; Cephalosporins; Furans; Humans; Injections, Intramuscular; Injections, Intravenous; Kinetics; Male; Middle Aged; Probenecid; Protein Binding

1976
Relationship between the transport and toxicity of cephalosporins in the kidney.
    The Journal of infectious diseases, 1975, Volume: 132, Issue:2

    Topics: Acute Kidney Injury; Aminohippuric Acids; Animals; Animals, Newborn; Biological Transport; Cefazolin; Cephaloridine; Cephalosporins; Dose-Response Relationship, Drug; Drug Administration Schedule; Guinea Pigs; Kidney Cortex; Kidney Tubular Necrosis, Acute; Kidney Tubules, Proximal; Male; Probenecid; Rabbits; Rats

1975
Effect of probenecid on the pharmacokinetics of DQ-2556, a new 3-quaternary ammonium cephalosporin antibiotic, in humans.
    Chemotherapy, 1992, Volume: 38, Issue:6

    Topics: Administration, Oral; Adult; Cephalosporins; Dose-Response Relationship, Drug; Drug Interactions; Humans; Injections, Intravenous; Kidney; Male; Probenecid

1992
Pharmacokinetic interactions of cefprozil with food, propantheline, metoclopramide, and probenecid in healthy volunteers.
    Journal of clinical pharmacology, 1992, Volume: 32, Issue:8

    Topics: Adult; Cefprozil; Cephalosporins; Drug Interactions; Fasting; Food; Gastrointestinal Motility; Half-Life; Humans; Isomerism; Kidney Tubules; Male; Metabolic Clearance Rate; Metoclopramide; Middle Aged; Probenecid; Propantheline

1992
Probenecid effect on cefuroxime pharmacokinetics in calves.
    Journal of veterinary pharmacology and therapeutics, 1989, Volume: 12, Issue:1

    Topics: Animals; Cattle; Cefuroxime; Cephalosporins; Drug Interactions; Half-Life; Injections, Intramuscular; Injections, Intravenous; Male; Probenecid

1989
Effect of probenecid administration on cephapirin pharmacokinetics and concentrations in mares.
    American journal of veterinary research, 1989, Volume: 50, Issue:10

    Topics: Animals; Ascitic Fluid; Cephalosporins; Cephapirin; Drug Interactions; Endometrium; Female; Horses; Probenecid; Synovial Fluid

1989
Effect of probenecid on disposition of cefpiramide in rat. The application of population pharmacokinetics.
    Chemical & pharmaceutical bulletin, 1987, Volume: 35, Issue:3

    Topics: Animals; Cephalosporins; Chromatography, High Pressure Liquid; Kinetics; Male; Probenecid; Rats; Rats, Inbred Strains

1987
Kinetic evidence for a common transport route of benzylpenicillin and probenecid by freshly prepared hepatocytes in rats. Influence of sodium ion, organic anions, amino acids and peptides on benzylpenicillin uptake.
    Journal of pharmacobio-dynamics, 1986, Volume: 9, Issue:1

    Topics: Amino Acids; Animals; Anions; Cattle; Cephalosporins; In Vitro Techniques; Kinetics; Liver; Male; p-Aminohippuric Acid; Penicillin G; Peptides; Probenecid; Rats; Rats, Inbred Strains; Serum Albumin; Serum Albumin, Bovine; Sodium; Taurocholic Acid

1986
Effect of probenecid on cerebrospinal fluid concentrations of penicillin and cephalosporin derivatives.
    Antimicrobial agents and chemotherapy, 1974, Volume: 6, Issue:4

    Topics: Animals; Cephalosporins; Drug Synergism; Meningitis, Pneumococcal; Penicillins; Probenecid; Rabbits; Reference Values

1974
Cefazolin in the treatment of gonorrhea.
    The Journal of infectious diseases, 1973, Volume: 128

    Topics: Cephaloridine; Cephalosporins; Cephalothin; Drug Evaluation; Drug Resistance, Microbial; Drug Therapy, Combination; Female; Gonorrhea; Humans; Male; Microbial Sensitivity Tests; Neisseria gonorrhoeae; Probenecid; Sulfides; Tetrazoles; Thiadiazoles

1973
Pharmacological studies on cephacetrile in human volunteers.
    Current medical research and opinion, 1974, Volume: 2, Issue:5

    Topics: Adult; Bacillus subtilis; Bicarbonates; Blood; Buttocks; Cephalosporins; Female; Humans; Injections, Intramuscular; Injections, Intravenous; Lidocaine; Male; Probenecid; Thigh; Urine

1974
Treatment of gonorrhea with cefazolin plus probenecid.
    The Journal of infectious diseases, 1974, Volume: 130, Issue:4

    Topics: Administration, Oral; Adult; Cephalosporins; Drug Evaluation; Drug Therapy, Combination; Female; Gonorrhea; Humans; Injections; Male; Neisseria gonorrhoeae; Penicillin G Procaine; Probenecid; Sulfides; Tetrazoles; Thiadiazoles

1974
Cephaloridine: antimicrobial activity and pharmacologic behavior.
    The American journal of the medical sciences, 1967, Volume: 253, Issue:6

    Topics: Adult; Alcaligenes; Cephaloridine; Cephalosporins; Cephalothin; Drug Synergism; Enterobacteriaceae; Enterococcus faecalis; Escherichia coli; Haemophilus influenzae; Humans; Klebsiella; Methicillin; Penicillin G; Probenecid; Proteus; Pseudomonas aeruginosa; Salmonella; Staphylococcus; Streptococcus; Streptococcus pneumoniae; Streptococcus pyogenes; Tetracycline

1967
In vitro antimicrobial activity and human pharmacology of cephaloglycin.
    Applied microbiology, 1968, Volume: 16, Issue:7

    Topics: Bacteria; Cephalosporins; Enterobacter; Escherichia coli; Humans; Klebsiella; Probenecid; Proteus; Staphylococcus; Streptococcus pneumoniae; Streptococcus pyogenes; Urinary Tract Infections

1968
Pharmacokinetics of parenteral sodium cephalexin in comparison with cephalothin and cefazolin.
    Infection, 1974, Volume: 2, Issue:3

    Topics: Adult; Cephalexin; Cephalosporins; Cephalothin; Half-Life; Humans; Injections, Intramuscular; Injections, Intravenous; Kinetics; Male; Probenecid; Sulfides; Tetrazoles; Thiadiazoles

1974
Some determinants of the distribution of penicillins and cephalosporins in the body. Practical and theoretical considerations.
    Annals of the New York Academy of Sciences, 1974, May-10, Volume: 235, Issue:0

    Topics: Albumins; Binding Sites; Biopharmaceutics; Blood Proteins; Capillary Permeability; Cephalosporins; Half-Life; Humans; Hydrogen-Ion Concentration; Kidney Failure, Chronic; Kinetics; Penicillins; Probenecid; Protein Binding

1974
Amoxycillin in the treatment of gonorrhoea.
    The British journal of venereal diseases, 1972, Volume: 48, Issue:6

    Topics: Acute Disease; Amines; Ampicillin; Benzyl Compounds; Cephalosporins; Gonorrhea; Humans; Male; Penicillins; Phenols; Probenecid; Recurrence; Tetracycline

1972
[Probenecid and antibiotics].
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1972, Dec-30, Volume: 92, Issue:35

    Topics: Cephalosporins; Drug Synergism; Half-Life; Humans; Penicillins; Probenecid; Stimulation, Chemical

1972
Cephamycins, a new family of beta-lactam antibiotics. IV. In vivo studies.
    Antimicrobial agents and chemotherapy, 1972, Volume: 2, Issue:4

    Topics: Animals; Bacterial Infections; Cephalosporins; Female; Mice; Probenecid

1972
Pharmacodynamics of cefazolin in the presence of normal and impaired renal function.
    Antimicrobial agents and chemotherapy, 1973, Volume: 4, Issue:3

    Topics: Cephalosporins; Creatinine; Drug Interactions; Half-Life; Humans; Kidney Failure, Chronic; Kidney Function Tests; Probenecid; Sulfides; Tetrazoles; Thiadiazoles

1973
Penetration of antibiotics into fibrin loci in vivo. 3. Intermittent vs. continuous infusion and the effect of probenecid.
    The Journal of infectious diseases, 1974, Volume: 129, Issue:1

    Topics: Ampicillin; Animals; Anti-Bacterial Agents; Blood Coagulation; Cephalosporins; Fibrin; Injections, Intravenous; Kanamycin; Kidney Tubules; Oxacillin; Probenecid; Rabbits; Streptomycin

1974
Cefoxitin, a semisynthetic cephamycin antibiotic: in vivo evaluation.
    Antimicrobial agents and chemotherapy, 1974, Volume: 5, Issue:1

    Topics: Animals; Biological Assay; Carbamates; Cephalosporins; Drug Evaluation; Enterobacteriaceae Infections; Female; Methyl Ethers; Probenecid

1974
Effects of synthetic penicillin and cephalosporin on thyroxine-plasma protein interaction in the rat.
    Archives internationales de pharmacodynamie et de therapie, 1969, Volume: 182, Issue:1

    Topics: Animals; Cephaloridine; Cephalosporins; Cephalothin; Cloxacillin; Iodine Isotopes; Liver; Male; Methicillin; Oxacillin; Penicillin V; Penicillins; Probenecid; Protein Binding; Rats; Thyroid Gland; Thyroidectomy; Thyroxine; Thyroxine-Binding Proteins

1969
Clinical pharmacology of cephalexin administered by intravenous injection.
    Journal of clinical pathology, 1972, Volume: 25, Issue:6

    Topics: Adult; Cephalexin; Cephalosporins; Female; Half-Life; Humans; Injections, Intravenous; Kidney Failure, Chronic; Male; Probenecid; Renal Dialysis; Time Factors

1972
Cephalexin in the treatment of gonorrhea.
    International journal of clinical pharmacology, therapy and toxicology, 1972, Volume: 6, Issue:1

    Topics: Cephalexin; Cephalosporins; Drug Resistance, Microbial; Gonorrhea; Humans; Male; Microbial Sensitivity Tests; Probenecid

1972
Chemotherapy of gonorrhea: a review of current status.
    Canadian Medical Association journal, 1972, Nov-18, Volume: 107, Issue:10

    Topics: Anti-Bacterial Agents; Cephalosporins; Chloramphenicol; Erythromycin; Gonorrhea; Humans; Kanamycin; Penicillins; Probenecid; Rifampin; Sulfonamides; Trimethoprim

1972
Use of Probenecid in antimicrobial therapy.
    The Medical letter on drugs and therapeutics, 1971, Volume: 13, Issue:21

    Topics: Cephalosporins; Drug Hypersensitivity; Drug Synergism; Humans; Penicillins; Probenecid

1971
Nephron transport and renal tubular effects of cephaloridine in animals.
    British journal of pharmacology and chemotherapy, 1967, Volume: 30, Issue:2

    Topics: Aminohippuric Acids; Animals; Cephaloridine; Cephalosporins; Dogs; Female; Inulin; Kidney Tubules; Male; Mice; Poultry; Probenecid; Rabbits; Sodium

1967
Effect of probenecid on the pharmacokinetics of moxalactam.
    Antimicrobial agents and chemotherapy, 1982, Volume: 21, Issue:1

    Topics: Adult; Anti-Bacterial Agents; Cephalosporins; Cephamycins; Drug Interactions; Humans; Kidney; Kinetics; Male; Middle Aged; Moxalactam; Probenecid

1982
Gonococcal infections: new methods of treatment.
    Comprehensive therapy, 1982, Volume: 8, Issue:6

    Topics: Anti-Bacterial Agents; Cephalosporins; Diagnosis, Differential; Drug Therapy, Combination; Female; Gonorrhea; Humans; Male; Neisseria gonorrhoeae; Penicillin Resistance; Penicillins; Pregnancy; Pregnancy Complications, Infectious; Probenecid; Spectinomycin; Tetracyclines; Urethritis

1982
Renal disposition of moxalactam in experimental animals as revealed by stop-flow analysis.
    Antimicrobial agents and chemotherapy, 1983, Volume: 23, Issue:1

    Topics: Animals; Anti-Bacterial Agents; Blood Proteins; Cephalosporins; Cephamycins; Dogs; Kidney; Macaca fascicularis; Male; Metabolic Clearance Rate; Moxalactam; p-Aminohippuric Acid; Probenecid; Protein Binding; Rabbits; Species Specificity

1983
The treatment of gonococcal urethritis with cefotaxime [proceedings].
    The Journal of antimicrobial chemotherapy, 1980, Volume: 6 Suppl A

    Topics: Cefotaxime; Cephalosporins; Drug Therapy, Combination; Gonorrhea; Humans; Male; Probenecid; Urethritis

1980
Studies on absorption, distribution, metabolism and excretion of ceftazidime in Japan.
    The Journal of antimicrobial chemotherapy, 1983, Volume: 12 Suppl A

    Topics: Adult; Alcohol Deterrents; Bile; Cefoperazone; Ceftazidime; Cephalosporins; Dose-Response Relationship, Drug; Gallbladder; Half-Life; Humans; Infusions, Parenteral; Injections, Intravenous; Japan; Kidney Diseases; Male; Probenecid; Tissue Distribution

1983
Ceftazidime in cystic fibrosis: pharmacokinetics and therapeutic response.
    The Journal of antimicrobial chemotherapy, 1983, Volume: 12 Suppl A

    Topics: Adolescent; Adult; Ceftazidime; Cephalosporins; Child; Cystic Fibrosis; Female; Humans; Kinetics; Male; Premedication; Probenecid; Pseudomonas Infections; Respiratory Tract Infections

1983
Influence of probenecid on serum and subcutaneous tissue fluid concentrations of benzylpenicillin and ceftazidime in human volunteers.
    European journal of clinical microbiology, 1983, Volume: 2, Issue:6

    Topics: Adult; Ceftazidime; Cephalosporins; Humans; Kinetics; Penicillin G; Probenecid

1983
Cefoperazone: absorption, excretion, distribution, and metabolism.
    Clinical therapeutics, 1980, Volume: 3, Issue:Spec Issue

    Topics: Adult; Animals; Ascitic Fluid; Bile; Cefoperazone; Cephalosporins; Dogs; Female; Haplorhini; Humans; Injections, Intramuscular; Injections, Intravenous; Kidney Diseases; Kinetics; Male; Maternal-Fetal Exchange; Maxillary Sinus; Mice; Palatine Tonsil; Pregnancy; Probenecid; Rabbits; Rats; Sputum; Tissue Distribution

1980
[Mechanism of renal excretion of ceftizoxime in rabbits and dogs (author's transl)].
    The Japanese journal of antibiotics, 1980, Volume: 33, Issue:6

    Topics: Animals; Ceftizoxime; Cephalosporins; Dogs; Kidney; Kidney Tubules; Male; Probenecid; Rabbits

1980
GR 20263, a new broad-spectrum cephalosporin with anti-pseudomonal activity.
    Antimicrobial agents and chemotherapy, 1980, Volume: 17, Issue:5

    Topics: Adult; Animals; Bacteria; Bacterial Infections; beta-Lactamases; Blood Proteins; Ceftazidime; Cephalosporins; Female; Humans; Hydrolysis; Injections, Intramuscular; Injections, Intravenous; Male; Mice; Microbial Sensitivity Tests; Middle Aged; Probenecid; Protein Binding; Pseudomonas

1980
[Pharmacokinetic interference between furosemide and cephalosporins].
    Antibiotiki, 1981, Volume: 26, Issue:4

    Topics: Animals; Cephalosporins; Drug Interactions; Furosemide; Kidney; Kinetics; Probenecid; Rats; Time Factors

1981
Pharmacokinetics of cephradine given intravenously with and without probenecid.
    British journal of clinical pharmacology, 1981, Volume: 11, Issue:6

    Topics: Adult; Cephalosporins; Cephradine; Humans; Injections, Intravenous; Kinetics; Male; Probenecid; Tissue Distribution

1981
Kinetics and renal handling of cefonicid.
    Clinical pharmacology and therapeutics, 1981, Volume: 30, Issue:5

    Topics: Adult; Anti-Bacterial Agents; Cefamandole; Cefonicid; Cephalosporins; Half-Life; Humans; Kidney; Kinetics; Male; Metabolic Clearance Rate; Probenecid

1981
Failure of probenecid to alter the pharmacokinetics of ceforanide.
    Antimicrobial agents and chemotherapy, 1981, Volume: 20, Issue:4

    Topics: Adult; Cefamandole; Cephalosporins; Drug Interactions; Female; Humans; Male; Middle Aged; Probenecid; Saliva

1981
Evidence of human serum albumin beta-lactamase activity.
    Biochemistry and molecular biology international, 1994, Volume: 32, Issue:4

    Topics: Animals; beta-Lactamases; Binding Sites; Binding, Competitive; Cephalosporins; Goats; Horses; Humans; Hydrogen-Ion Concentration; Ibuprofen; Kinetics; Oleic Acid; Oleic Acids; Probenecid; Serum Albumin; Serum Albumin, Bovine; Species Specificity; Swine; Urea

1994
Influence of probenecid on the renal excretion mechanisms of cefadroxil.
    Drug metabolism and disposition: the biological fate of chemicals, 1996, Volume: 24, Issue:2

    Topics: Animals; Cefadroxil; Cephalosporins; Drug Interactions; Kidney; Male; Metabolic Clearance Rate; Probenecid; Rats; Rats, Wistar; Renal Agents

1996
Comparison of dose doubling with probenecid for sustaining serum cefuroxime levels.
    The Journal of antimicrobial chemotherapy, 1997, Volume: 40, Issue:6

    Topics: Adolescent; Adult; Area Under Curve; Biological Availability; Cefuroxime; Cephalosporins; Drug Interactions; Female; Half-Life; Humans; Male; Metabolic Clearance Rate; Middle Aged; Probenecid; Renal Agents

1997
Role of organic anion transporter 1 (OAT1) in cephaloridine (CER)-induced nephrotoxicity.
    Kidney international, 1999, Volume: 56, Issue:6

    Topics: Animals; Anion Transport Proteins; Anticholesteremic Agents; Antigens, Polyomavirus Transforming; Biological Transport; Carbon Radioisotopes; Carrier Proteins; Cell Line; Cell Survival; Cephaloridine; Cephalosporins; DNA, Complementary; Kidney Diseases; Kidney Tubules, Proximal; Lipid Peroxidation; Mice; Mice, Transgenic; Mutagenesis; p-Aminohippuric Acid; Probenecid; Probucol; Uricosuric Agents

1999
Effects of organic anion, organic cation, and dipeptide transport inhibitors on cefdinir in the isolated perfused rat kidney.
    Antimicrobial agents and chemotherapy, 2003, Volume: 47, Issue:2

    Topics: Animals; Biological Transport; Cefdinir; Cephalosporins; Chromatography, High Pressure Liquid; Dipeptides; Kidney; Male; Metabolic Clearance Rate; Probenecid; Protein Binding; Rats; Rats, Sprague-Dawley; Tetraethylammonium

2003
Interaction of human and rat organic anion transporter 2 with various cephalosporin antibiotics.
    European journal of pharmacology, 2003, Mar-28, Volume: 465, Issue:1-2

    Topics: Animals; Anti-Bacterial Agents; Biological Transport; Cefadroxil; Cefamandole; Cefazolin; Cefoperazone; Cefotaxime; Ceftriaxone; Cell Line; Cell Survival; Cephaloridine; Cephalosporins; Cephalothin; Dinoprost; Dose-Response Relationship, Drug; Humans; Kinetics; Mice; Mice, Transgenic; Organic Anion Transporters, Sodium-Independent; Probenecid; Rats; Transfection; Uricosuric Agents

2003
Molecular mechanisms of biliary excretion of cefditoren and the effects of cefditoren on the expression levels of hepatic transporters.
    Drug metabolism and pharmacokinetics, 2010, Volume: 25, Issue:4

    Topics: Animals; Anti-Bacterial Agents; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Bile; Cephalosporins; Drug Interactions; Liver; Male; Novobiocin; Organic Anion Transporters, Sodium-Independent; Probenecid; Rats; Rats, Wistar; RNA, Messenger; Verapamil

2010