cephalosporin c has been researched along with pivalic acid in 10 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 7 (70.00) | 18.2507 |
| 2000's | 2 (20.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (10.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hashimoto, H; Konishi, M | 1 |
| Konishi, M; Shimizu, K; Totsuka, K; Yamamoto, S | 1 |
| Matsuno, S; Mizojiri, K; Nakashima, M; Oguma, T; Uematsu, T; Yamamoto, S; Yoshida, T | 1 |
| Futaguchi, S; Katsuyama, Y; Mizojiri, K; Nagasaki, T; Nakanishi, M; Norikura, R; Yoshimori, T | 1 |
| Chiba, S; Fujii, R; Meguro, H; Mori, A; Mori, T; Numazaki, K; Satoh, Y; Sunakawa, K; Terashima, I; Toyonaga, Y | 1 |
| Fujita, Y; Hiraga, Y; Inamatsu, T; Nishikawa, T; Ohmichi, M; Saito, A; Shimada, J; Shimada, K; Shimizu, K; Tanimura, M | 1 |
| Aretz, W; Meiwes, J; Sauber, K; Wollmann, T | 1 |
| Ito, T; Koyama, N; Makino, Y; Sugiura, T; Sugiyama, N | 1 |
| Ito, T | 1 |
| Hinotsu, S; Kitamura, Y; Koyama, T; Mikami, N; Sendo, T; Tatebe, Y | 1 |
1 review(s) available for cephalosporin c and pivalic acid
| Article | Year |
|---|---|
Children's toxicology from bench to bed--Liver injury (1): Drug-induced metabolic disturbance--toxicity of 5-FU for pyrimidine metabolic disorders and pivalic acid for carnitine metabolism.
Topics: Amidohydrolases; Animals; Anti-Bacterial Agents; Antineoplastic Agents; Carnitine; Cephalosporins; Child; Dihydropyrimidine Dehydrogenase Deficiency; Female; Fluorouracil; Humans; Intestinal Absorption; Pentanoic Acids; Purine-Pyrimidine Metabolism, Inborn Errors; Pyrimidines; Rats | 2009 |
1 trial(s) available for cephalosporin c and pivalic acid
| Article | Year |
|---|---|
Phase I clinical studies of S-1108: safety and pharmacokinetics in a multiple-administration study with special emphasis on the influence on carnitine body stores.
Topics: Adult; Carnitine; Cephalosporins; Drug Administration Schedule; Drug Evaluation; Humans; Male; Pentanoic Acids; Tablets | 1992 |
8 other study(ies) available for cephalosporin c and pivalic acid
| Article | Year |
|---|---|
Determination of pivaloylcarnitine in human plasma and urine by high-performance liquid chromatography with fluorescence detection.
Topics: Calibration; Carnitine; Cephalosporins; Chromatography, High Pressure Liquid; Drug Stability; Humans; Pentanoic Acids; Prodrugs; Quinoxalines; Sensitivity and Specificity; Spectrometry, Fluorescence | 1992 |
Metabolism of S-1108, a new oral cephem antibiotic, and metabolic profiles of its metabolites in humans.
Topics: Administration, Oral; Adult; Anti-Bacterial Agents; Carnitine; Cephalosporins; Humans; Male; Pentanoic Acids | 1992 |
Disposition of S-1108, a new oral cephem antibiotic, and metabolic fate of pivalic acid liberated from [pivaloyl-14C]S-1108 in rats and dogs.
Topics: Animals; Carbon Radioisotopes; Cephalosporins; Chromatography, Thin Layer; Dogs; Male; Pentanoic Acids; Prodrugs; Rats; Rats, Sprague-Dawley; Tissue Distribution | 1995 |
[Effect of cefditoren pivoxil on carnitine metabolism in pediatric patients].
Topics: Bacterial Infections; Carnitine; Cephalosporins; Child; Child, Preschool; Female; Humans; Infant; Male; Pentanoic Acids | 1993 |
Carnitine status and safety after administration of S-1108, a new oral cephem, to patients.
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Bacterial Infections; Carnitine; Cephalosporins; Female; Humans; Kidney Diseases; Male; Middle Aged; Pentanoic Acids; Prodrugs | 1993 |
A new esterase for the cleavage of pivalic acid-containing prodrug esters of cephalosporins.
Topics: Actinobacteria; Amino Acid Sequence; Cephalosporins; Esterases; Esters; Fermentation; Kinetics; Molecular Sequence Data; Pentanoic Acids; Peptide Fragments; Prodrugs; Substrate Specificity | 1996 |
Carnitine-associated encephalopathy caused by long-term treatment with an antibiotic containing pivalic acid.
Topics: Acidosis; Anti-Bacterial Agents; Brain Diseases, Metabolic; Carnitine; Cephalosporins; Humans; Hypoglycemia; Infant; Infusions, Intravenous; Male; Otitis Media; Pentanoic Acids; Seizures; Unconsciousness; Vitamin B Complex | 2007 |
Hypoglycemia associated with pivalate-conjugated antibiotics in young children: A retrospective study using a medical and pharmacy claims database in Japan.
Topics: Anti-Bacterial Agents; Antimicrobial Stewardship; Cephalosporins; Child, Preschool; Comorbidity; Databases, Factual; Female; Humans; Hypoglycemia; Infant; Japan; Male; Pentanoic Acids; Retrospective Studies | 2020 |