cephalosporin c has been researched along with penicillanic acid in 391 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 65 (16.62) | 18.7374 |
| 1990's | 40 (10.23) | 18.2507 |
| 2000's | 68 (17.39) | 29.6817 |
| 2010's | 200 (51.15) | 24.3611 |
| 2020's | 18 (4.60) | 2.80 |
| Authors | Studies |
|---|---|
| Elizarovskaia, LM; Nys, PS; Savitskaia, EM; Shellenberg, NN | 1 |
| Dewdney, JM; Munro, AC; Smith, H; Wheeler, AW | 1 |
| Chojnowski, W; Gralewicz, J; Jastalska, D; Morris-Rostkowska, W; Zapaśnik, M | 1 |
| Bremner, DH; Campbell, MM; Johnson, G | 1 |
| Bortesi, F; Cavalli, S; Mangia, A | 1 |
| Di Bitetto, M; Mangia, A; Silingardi, S | 1 |
| Morohoshi, T; Saito, T | 1 |
| Abraham, EP | 1 |
| Spratt, BG | 1 |
| Rolinson, GN | 1 |
| Csiba, A; Czéh, I | 1 |
| Chattopadhyay, B; Hall, I | 1 |
| Anderson, F; Brumfitt, W; Franklin, I; Hamilton-Miller, J | 1 |
| Abraham, EP; Cornelis, G | 1 |
| Ellis, LF; Herron, DK; Preston, DA; Schlegel, RA; Simmons, LK | 1 |
| Atanassova, T; Ivanova, Z; Mondeshka, D; Nakov, A; Petrova, Z | 1 |
| Dall'Asta, L; Ferri, V; Pallavacini, M; Pessa, A; Valoti, E; Villa, L | 1 |
| Aspinall, S; Corkill, JE; Hart, CA; McLennan, AG | 1 |
| Bauernfeind, A; Eberlein, E; Jungwirth, R; Schweighart, S | 1 |
| Christensen, H; Martin, MT; Waley, SG | 1 |
| Dornbusch, K; Göransson, E; Mörtsell, E | 1 |
| Adkinson, NF; Saxon, A; Swabb, EA | 1 |
| Hirose, T; Matsumoto, J; Mishio, S; Nakano, J | 1 |
| Acar, JF; Billot-Klein, D; Carlet, J; Goldstein, FW; Gutmann, L; Kitzis, MD; Tran Van Nhieu, G; Williamson, R | 1 |
| Knight, GC; Waley, SG | 1 |
| Chin, NX; Labthavikul, P; Neu, HC | 1 |
| Barry, AL; Jones, RN; Thornsberry, C; Wilson, HW | 1 |
| Rice, RJ; Thompson, SE | 1 |
| Gargani, G; Pacetti, AM | 1 |
| Briese, T; Ellerbrok, H; Hakenbeck, R | 1 |
| McDougal, LK; Thornsberry, C | 1 |
| Bodanszky, M; Perlman, D | 1 |
| Blumberg, PM; Strominger, JL | 2 |
| Lemke, PA; Nash, CH | 1 |
| Hou, JP; Poole, JW | 1 |
| Heusler, K | 1 |
| Karrington, TR | 1 |
| Döker, H; Moll, F | 1 |
| Chauvette, RR; Hayes, HB; Huff, GL; Pennington, PA | 1 |
| Davies, JV; Phillips, GO; Power, DM; Robinson, C | 1 |
| Citri, N; Kalkstein, A; Zyk, N | 1 |
| Brumfitt, W; Hamilton-Miller, JM | 1 |
| Vandamme, EJ; Voets, JP | 1 |
| Chain, E | 1 |
| Celozzi, E; Gadebusch, HH; Pelak, BA; Stapley, EO | 1 |
| García-Iglesias, MC; Palomares, JC; Perea, EJ | 1 |
| Yamabe, S | 1 |
| Rahman, M | 1 |
| Kondo, M; Tsuchiya, K | 1 |
| Arnold, K; Chau, PY; Ling, J; Ng, WS | 1 |
| Fu, KP; Neu, HC | 1 |
| Washington, JA; Yu, PK | 1 |
| Mantoku, A; Ogawara, H | 1 |
| Frère, JM; Ghuysen, JM; Kelly, JA; Klein, D | 1 |
| Fass, RJ | 1 |
| Beskid, G; Cleeland, R; Grimm, LM; McCracken, GH; Nelson, JD; Schaad, UB | 1 |
| Crosby, MA; Gump, DW | 1 |
| Bailey, RR; Bishop, V; Blake, E; Chambers, PF; Crofts, HG; Davies, PR; Peddie, B | 1 |
| Arisawa, M; Then, RL | 1 |
| Borowski, J; Zaremba, M; Zukowska-Nytko, K | 1 |
| Foulds, G; Hayes, SL; Marshall, DC; McMahon, FG; O'Brien, MM; Stankewich, JP; Weidler, DJ | 1 |
| Kusmiesz, H; Nelson, JD; Shelton, S | 1 |
| Baumgärtner, M; Müller, HP; Wundt, W | 1 |
| Gestrelius, S; Møllgaard, H; Nielsen, BH | 1 |
| Baumgärtner, M | 1 |
| Fu, KP; Kimble, EF; Konopka, EA; Zoganas, H | 1 |
| Sosnovskaya, IN; Yatsimirskaya, NT; Yatsimirsky, AK | 1 |
| Cony Makhoul, P; Darmaillac, V; Fourche, J; Maugein, J; Perrier, F | 1 |
| Bartoshevich, IuE; Nys, PS | 1 |
| Harris, EB; Hastings, RC; Prabhakaran, K; Randhawa, B | 1 |
| Matsumoto, K | 1 |
| Gorbach, SL | 1 |
| Denny, BJ; Lambert, PA; Toomer, CA | 1 |
| Bush, K; Lee, VJ; Macalintal, C; Rasmussen, BA; Yang, Y | 1 |
| Bonomo, RA; Carias, LL; Rice, LB; Shlaes, DM | 1 |
| Demonty, J | 1 |
| Alonso, JM; Fournier, JL; Jacolot, AC; Petitjean, OJ; Ramisse, F; Scavizzi, MR; Szatanik, M | 1 |
| Alós, JI; Balas, D; Cogollos, R; Gomez-Graces, JL; Tajada, P | 1 |
| Livermore, DM; Yuan, M | 1 |
| Abraham, EP; Whiteman, PA | 1 |
| Knapp, CC; Ludwig, MD; Pohlman, JK; Washington, JA | 1 |
| Lucas, L; Schügerl, K; Yang, ZF | 1 |
| Blumer, JL; Bonafede, ME | 1 |
| Eliopoulos, GM; Moellering, RC; Thauvin-Eliopoulos, C; Tripodi, MF | 1 |
| Hanaki, H; Nagayama, A; Nomura, S | 1 |
| Constantoulaki, S; Paniara, O; Platsouka, E; Zissis, NP | 1 |
| Brière, S; Brun-Buisson, C; Petit, C; Schweich, H; Sollet, JP | 1 |
| Barthélémy, M; Caniça, MM; Caroff, N; Dupret, JM; Krishnamoorthy, R; Labia, R; Paul, G | 1 |
| Amicosante, G; Cornaglia, G; Franceschini, N; Mazzariol, A; Perilli, M; Segatore, B; Setacci, D | 1 |
| Böhme, A; Hoelzer, D; Shah, PM; Stille, W | 1 |
| Andremont, A; Guy, H; Marie, JP; Pico, JL; Richet, H; Vekhoff, A | 1 |
| Chang, MH; Cho, YS; Choi, KI; Ha, YJ; Koh, HY; Kwon, JS; Lee, GS; Pae, AN; Yoon, CM | 1 |
| Baudard, M; Bouvet, A; Chast, F; Delmer, A; Legrand, O; Levy, V; Marie, JP; Marjanovic, Z; Rio, B; Vekhoff, A; Zittoun, R | 1 |
| Ell, C; Gossner, L; Hahn, EG; Keymling, J | 1 |
| Buxbaum, A; Georgopoulos, A; Graninger, W | 1 |
| Atchison, KP; Atwal, H; Higashitani, F; Hyodo, A; Kunugita, C; Maiti, SN; Micetich, RG; Nishida, K; Phillips, OA; Salama, SM; Spevak, P; Uji, T; Unemi, N | 1 |
| Elhelali, N; Jacolot, A; Laurent, F; Léotard, S; Mimoz, O; Nordmann, P; Petitjean, O; Samii, K | 1 |
| Allerberger, F; Feierl, G; Hirschl, A; Krause, R; Mittermayer, H; Reisinger, EC; Wendelin, I | 1 |
| Kays, MB | 1 |
| Bonafede, M; Bonomo, RA; Carias, LL; Hoyen, C; Hujer, AM; Hutton, R; Rice, LB | 1 |
| Kaloyanov, N; Stoyanova, R | 1 |
| Bradley, SJ | 1 |
| Cross, JM; May, AK; McGwin, G; Melton, SM; Moser, SA; Rue, LW | 1 |
| Amicosante, G; Belloni, R; Bianchi, C; Lombardi, G; Luzzaro, F; Perilli, M; Toniolo, A; Zollo, A | 1 |
| Anstead, G; Blaser, M; Craig, F; Jorgensen, J; Patterson, T | 1 |
| Alvarez-Lerma, F; Barcenilla, F; Insausti-Ordeñana, J; Jordá-Marcos, R; Maraví-Poma, E; Martínez-Pellús, A; Nava, J; Palomar, M; Torres-Martí, A | 1 |
| Bauduer, F; Boiron, JM; Boulat, O; Cousin, T; Fegueux, N; Jourdan, E; Molina, L; Reiffers, J; Rigal-Huguet, F | 1 |
| Moland, ES; Thomson, KS | 1 |
| Beyer, M; Jakobsen, M; Nielsen, J; Noorman, H; Robin, J | 1 |
| Bliznakov, M; Kaloyanov, N; Stoyanova, R; Traldi, P | 1 |
| Prashad, AS; Sandanayaka, VP | 1 |
| Batlle, M; Benlloch, L; Capote, FJ; Gutiérrez, M; Jarque, I; Julià, A; Lahuerta, JJ; Larrea, L; López, J; Palau, J; Pérez, C; Ramos, F; Rovira, M; Sanz, MA; Vázquez, L | 1 |
| Jones, RN; Mutnick, AH; Turner, PJ | 1 |
| Burgess, DS; Nathisuwan, S | 1 |
| Chilov, GG; Shcherbakova, TA; Svedas, VK; Youshko, MI | 1 |
| Powell, LL; Wilson, SE | 1 |
| Balestrini, AA; Beric, V; Kibbler, CC; Quick, A; Stone, SP | 1 |
| Gesser, RM; McCarroll, K; Teppler, H; Woods, GL | 1 |
| Ambrose, PG; Bhavnani, SM; Jones, RN | 1 |
| Kotapati, S; Kuti, JL; Nicolau, DP; Nightingale, CH | 1 |
| Charlett, A; Henwood, CJ; James, D; Johnson, AP; Livermore, DM; Mushtaq, S; Potz, N; Walker, RA; Warburton, F; Warner, M | 1 |
| Alkema, WB; de Vries, E; Floris, R; Janssen, DB | 1 |
| Maier, A; Smolle-Jüttner, FM; Tomaselli, F | 1 |
| HUANG, HT; SETO, TA; SHULL, GM | 1 |
| WALTON, RB | 1 |
| JAGO, M | 1 |
| DAY, RA; SHAH, R; YIP, LC | 1 |
| Ceran, N; Erdem, I; Kucukercan, M | 1 |
| Arango, C; Bantar, C; Coassolo, MA; Duret, F; Fiorillo, A; Franco, D; Gomez, H; Heft, C; Krayeski, M; Oliva, ME; Salamone, F; Vesco, E | 1 |
| Boosten, WH; Bukhanov, AL; Moody, HM; Svedas, VK; Youshko, MI | 1 |
| Choi, MK; Fish, DN; Husain, M; Jung, R | 1 |
| Blosser-Middleton, RS; Ge, Y; Karlowsky, JA; Sahm, DF; Wikler, MA | 1 |
| Goessens, WH; Gyssens, IC; Lemmens, N; Mouton, JW; Stearne, LE; van Boxtel, D | 1 |
| Høiby, N; Walther-Rasmussen, J | 1 |
| Bethel, CR; Bonomo, RA; Helfand, MS; Hujer, AM | 1 |
| Burgess, DS; Hall, RG | 1 |
| Brown, A; Corrado, O; Donaldson, K; Fawley, W; Freeman, J; MacKinlay, S; Wilcox, MH | 1 |
| Bonnefoy, A; Delachaume, C; Dupuis-Hamelin, C; Fairley, M; Guitton, M; Lampilas, M; Seys, C; Stachyra, T; Steier, V | 1 |
| Burgess, DS; Frei, CR | 1 |
| Burgess, DS; Frei, CR; Reese, AM | 1 |
| Arora, V; Prakash, SK; Prashad, R; Sharma, VK | 1 |
| Kuti, JL; Nicolau, DP; Sun, HK | 1 |
| Fraser, A; Leibovici, L; Paul, M; Yahav, D | 1 |
| Capparelli, FJ; Del Castillo, ME; Diaz, MF; Hlavnika, A; Leiguarda, R; Wainsztein, NA | 1 |
| Hashikita, G; Kawakami, S; Kobayashi, S; Maesaki, S; Nagasawa, M; Okabe, T; Sasaki, K; Shibuya, S; Suzuki, N; Takayama, S; Uchida, T; Watanabe, M; Yamaguchi, T | 1 |
| Greenberg, A; Muallem-Zilcha, E; Raveh, D; Schlesinger, Y; Wiener-Well, Y; Yinnon, AM | 1 |
| Rice, LB | 1 |
| Bow, EJ; Laverdiere, M; Noskin, GA; Rotstein, C; Sanche, S; Schwarer, AP; Segal, BH; Seymour, JF; Szer, J | 1 |
| Chun, BC; Jeong, HW; Kim, MJ; Park, DW; Sohn, JW; Yang, JA | 1 |
| Gurkan, E; Hutton-Thomas, R; Lakticová, V; Meyer, M; Rice, LB | 1 |
| Agarwal, N; Agarwal, S; Arya, SC | 1 |
| de Cueto, M; Hernández, JR; Muniain, MA; Navarro, MD; Pascual, A; Ríos, MJ; Rodríguez-Baño, J; Romero, L | 1 |
| Geddes, AM; Rolinson, GN | 1 |
| Fritsche, TR; Hsiung, A; Jones, RN; Sader, HS | 1 |
| Avlamis, A; Daikos, GL; Markogiannakis, A; Papaparaskevas, J; Papapareskevas, J; Petrikkos, G; Stefanakos, G; Zissis, NP | 1 |
| Araujo, VR; Carvalho-Dias, VM; Cunha, CA; de Souza, CA; de Souza, M; Godoy, C; Lotfi, CJ; Maiolino, A; Nucci, M; Oliveira, AL; Pasquini, R; Ruiz, MA; Seber, A; Silla, L; Simões, BP; Tanaka, PY; Trabasso, P; Urakawa, P; Zanichelli, MA | 1 |
| Cheng, CJ; Chou, CH; Lin, CS; Lin, SH | 1 |
| Agarwal, N; Agarwal, S; Arya, SC; Solanki, BS | 1 |
| Kóczián, K; Kökösi, J; Noszál, B; Szakács, Z | 1 |
| Afonso, MR; Albertoni, Ade C; Arkader, R; Cabral, EA; da Silva, DC; de Araujo, OR; Diegues, AR; Louzada, ME | 1 |
| Braga, AL; Burattini, MN; Jukemura, EM; Medeiros, EA; Pereira, CA | 1 |
| Correia, A; Domingues, MR; Domingues, P; Fonseca, F; Henriques, I; Saavedra, MJ; Samyn, B; Sarmento, AC; van Beeumen, J | 1 |
| Hoda, MQ; Hussein, K; Manasia, R; Salahuddin, N; Samad, A; Siddiqui, S; Zafar, A | 1 |
| Aron, DC; Bonomo, RA; Capitano, B; Donskey, CJ; Linden, PK; Muto, CA; Ndirangu, M; Paterson, DL; Potoski, BA | 1 |
| Bai, YL; Chen, BY; Chu, YZ; Li, JB; Li, LY; Wan, JH; Wang, Q; Wang, X; Zhang, JP; Zhao, ZM | 1 |
| Arora, J; Dogra, A; Rao, P; Taneja, N | 1 |
| Klaustermeyer, W; Lam, A; Randhawa, I | 1 |
| Iguchi, A; Kaneda, M; Kobayashi, K; Kobayashi, R; Sato, T; Yasuda, K | 1 |
| Hazar, V; Karasu, GT; Ogunc, D; Uygun, V; Yesilipek, A | 1 |
| Kulkarni, KP; Pal, P; Pal, RB; Venkatesh, V | 1 |
| Albertí, S; Juan, C; Mulet, X; Oliver, A; Pérez, JL; Zamorano, L | 1 |
| Bulik, CC; Christensen, H; Nicolau, DP | 1 |
| Doherty, JA; Khan, J; Kollef, MH; Micek, ST; Pervez, M; Reichley, RM; Welch, EC | 1 |
| Bastús, R; Cirera, L; Estany, C; Estrada, C; Garau, J; Gómez, I; Gómez, L; Márquez, M; Martí, JM; Quintana, S | 1 |
| De Backer, D; Delattre, I; Dugernier, T; Jacobs, F; Laterre, PF; Layeux, B; Spapen, H; Taccone, FS; Vincent, JL; Wallemacq, P; Wittebole, X | 1 |
| Ge, Y; Livermore, DM; Mushtaq, S | 1 |
| Bivas, A; Fraser, A; Leibovici, L; Paul, M; Yahav, D | 1 |
| Appelbaum, PC; Armstrong, ES; Kosowska-Shick, K; Kubo, A; Lin, G; Pankuch, GA | 1 |
| Farrell, DJ; Jones, RN; Rhomberg, PR; Sader, HS | 1 |
| Cabot, G; Juan, C; Mark, BL; Moyá, B; Oliver, A; Reeve, TM; Vocadlo, DJ; Zamorano, L | 1 |
| Barshikar, S; Baylor, AE; Dolman, HS; Glowniak, J; Hong, K; Lavery, T; Nailor, M; Singla, R; Stassinopoulus, J; Tyburski, JG; Wilson, RF; Zimmerman, LH | 1 |
| Ariga, T; Cho, Y; Ichikawa, M; Iguchi, A; Kaneda, M; Ohshima, J; Suzuki, D | 1 |
| Bosso, JA; Church, EC; Mauldin, PD | 1 |
| Ge, Y; Giske, CG; Karlsson, IM; Titelman, E | 1 |
| Altunsoy, A; Aypak, C; Azap, A; Balık, I; Ergönül, Ö | 1 |
| Cotton, F; De Backer, D; Jacobs, F; Macours, P; Seyler, L; Taccone, FS; Vincent, JL | 1 |
| Kurochkina, VB; Satarova, JE; Sklyarenko, AV; Yarotsky, SV | 1 |
| Landau, Z; Miller, EB; Shichmanter, R; Shtalrid, M | 1 |
| Bulik, CC; Keel, RA; Nicolau, DP; Sutherland, CA; Tessier, PR | 1 |
| Kronenberg, A; Mühlemann, K; Pannatier, A; Plüss-Suard, C; Ruffieux, C; Zanetti, G | 1 |
| Homann, C; Knudsen, JD; Moser, C; Novovic, S; Olsen, H; Semb, S | 1 |
| Benziger, D; Friedland, I; Hershberger, E; Miller, B; Trinh, M | 1 |
| Hsueh, PR; Lee, YJ; Lin, YC; Liu, HY; Wu, HH | 1 |
| Bhargava, A; Bheemreddy, S; Chopra, T; Dhar, S; Gudur, UM; Hayakawa, K; Kaye, KS; Lephart, PR; Marchaim, D; Mynatt, RP; Sunkara, B; Zhao, JJ | 1 |
| Faoagali, J; Gallagher, JE; George, N; Gidding, HF; Ginn, AN; Iredell, JR; Lipman, J; O'Driscoll, JS; O'Toole, BI; Partridge, SR; Perri, RA; Wiklendt, AM | 1 |
| Chandorkar, G; Gotfried, MH; Huntington, JA; Rodvold, KA; Umeh, O | 1 |
| Adams, CA; Cioffi, WG; Connolly, MD; Gregg, S; Heffernan, DS; Monaghan, SF; Stephen, A; Thakkar, RK | 1 |
| Ampofo, K; Sherwin, CM; Spigarelli, MG; Stockmann, C; Waters, CD; Young, DC; Zobell, JT | 1 |
| Chander, J; Garg, R; Gulati, N; Gupta, V; Krishnan, P; Kumarasamy, K | 1 |
| Aziz, MN; Desa, MN; Idris, SN; Taib, NM | 1 |
| Beumier, M; Cotton, F; De Backer, D; Hites, M; Jacobs, F; Lorent, S; Roisin, S; Seyler, L; Surin, R; Taccone, FS; Vincent, JL; Wolff, F | 1 |
| Andes, DR; Craig, WA | 1 |
| Arnold, HM; Hampton, NB; Hoban, A; Hoffmann, J; Hollands, JM; Juang, PH; Kollef, MH; McCormick, S; Micek, ST; Reichley, RM; Skrupky, LP; Smith, JR | 1 |
| Akashi, K; Chong, Y; Ito, Y; Kamimura, T; Miyamoto, T; Shimoda, S; Shimono, N; Yakushiji, H | 1 |
| Ambrose, PG; Bhavnani, SM; Bulik, CC; Castanheira, M; Forrest, A; Friedrich, LV; Jones, RN; Mendes, RE; Nicasio, AM; Okusanya, OO; Steenbergen, JN; VanScoy, B | 1 |
| Hashiguchi, R; Komatsu, M; Matsuyama, S; Moronaga, Y; Nagahara, C; Oshiro, Y; Sameshima, I; Takeyama, H; Tottori, N; Yaita, K; Yamaguchi, Y | 1 |
| Browning, R; Darwiche, K; Freitag, L; Kioumis, I; Li, Q; Parrish, S; Petridis, D; Porpodis, K; Ritzoulis, C; Spyratos, D; Turner, JF; Zarogoulidis, K; Zarogoulidis, P | 1 |
| Adam, H; Baxter, M; Hoban, DJ; Karlowsky, JA; Lagacé-Wiens, P; Walkty, A; Zhanel, GG | 1 |
| Ambrose, PG; Bhavnani, SM; Bulik, CC; Forrest, A; Friedrich, LV; Jones, RN; McCauley, J; Mendes, RE; Okusanya, OO; Steenbergen, JN; Vanscoy, B | 1 |
| Farrell, DJ; Flamm, RK; Jones, RN; Sader, HS | 3 |
| Finnegan, PM; Hand, S; Linneman, TW; McDonald, JR; Moenster, RP; Thomas, Z | 1 |
| Arakawa, S; Fujisawa, M; Miyake, H; Shigemura, K; Tanaka, K | 1 |
| Jacobus, NV; McDermott, LA; Snydman, DR | 1 |
| Dharuman, JG; Vasudevan, M | 1 |
| Apisarnthanarak, A; Lye, DC; Ng, TM; Teng, CB | 1 |
| Adam, H; Chung, P; Denisuik, A; Gin, AS; Hoban, DJ; Karlowsky, JA; Lagacé-Wiens, PR; Lynch, JP; Rubinstein, E; Schweizer, F; Walkty, A; Zelenitsky, S; Zhanel, GG | 1 |
| Jones, RN; Rhomberg, PR; Sader, HS | 1 |
| Chandorkar, G; Hershberger, E; Krishna, G; Miller, B; Wooley, M | 1 |
| Feng, X; He, L; He, Y; Li, C; Liu, H; Liu, X; Ruan, Y; Wu, X; Zhang, Y | 1 |
| Bruchmann, S; Cabot, G; Haussler, S; Juan, C; Moyà, B; Mulet, X; Oliver, A; Zamorano, L | 1 |
| Doi, Y; Qureshi, ZA | 1 |
| Singh, HL; Singh, RM | 1 |
| Birch, A; Della Vecchia, BJ; Dupree, L; Gomes, DM; Jankowski, CA; Kraemer, DF; Smotherman, C | 1 |
| Gautam, V; Kaur, R; Ray, P; Singhal, L | 1 |
| Chu, X; Guo, YY; Liu, QZ; Shen, LM; Wang, J; Zhang, CL | 1 |
| Castanheira, M; Farrell, DJ; Flamm, RK; Jones, RN; Sader, HS | 1 |
| Friedland, I; Hershberger, E; Lucasti, C; Miller, B; Solomkin, J; Steenbergen, J; Yankelev, S | 1 |
| Wu, H; Xie, W; Ye, Z; Zhang, W; Zhao, C | 1 |
| Ambrose, PG; Bhavnani, SM; Castanheira, M; Friedrich, LV; Jones, RN; McCauley, J; Mendes, RE; Steenbergen, JN; VanScoy, BD | 1 |
| Chan, MC; Chang, FY; Lee, Y; Lin, JC; Lin, TY; Yang, YS; Yeh, KM | 1 |
| Boutoille, D; Bretonnière, C; Caillon, J; Desessard, C; Guitton, C; Jacqueline, C; Potel, G | 1 |
| Aguilar, L; Gilsanz, F; Gimenez, MJ; Maseda, E | 1 |
| Bush, K; Bussell, B; Clugston, SL; Estabrook, M | 1 |
| Castanheira, M; Farrell, DJ; Jones, RN; Mills, JC | 1 |
| Chandorkar, G; Hershberger, E; Krishna, G; Mouksassi, MS; Xiao, A | 1 |
| Kishimoto, K; Kobayashi, K; Kobayashi, R; Sano, H; Suzuki, D; Yasuda, K | 1 |
| Frey, L; Maier, B; Suhr, A; Teupser, D; Vogeser, M; Zander, J; Zoller, M | 1 |
| Bae, EY; Cho, B; Chung, NG; Han, SB; Jeong, DC; Jung, SW; Kang, JH; Kim, HK; Lee, DG; Lee, JW; Park, YJ | 1 |
| Eckmann, C; Solomkin, J | 1 |
| Duffy, A; Gilmore, S; Heil, EL; Nguyen, AD; Patel, NK | 1 |
| Barie, PS; Collins, S; Eckmann, C; Friedland, I; Hershberger, E; Miller, B; Popejoy, M; Solomkin, J; Steenbergen, J; Yoon, M; Yuan, G | 1 |
| Bassetti, M; Righi, E | 1 |
| Lagarde, C; Mavridou, E; Melchers, MJ; Mouton, JW; Seyedmousavi, S; van Mil, AC | 1 |
| Darouiche, RO; Steenbergen, J; Umeh, O; Wagenlehner, FM; Yuan, G | 1 |
| Chan, JF; Yuen, KY | 1 |
| Edwards, JK | 1 |
| Melchers, MJ; Mouton, JW; van Mil, AC | 1 |
| Cleveland, KO; Gelfand, MS | 1 |
| Al-Attas, A; Belal, F; El-Enany, N; Nasr, JJ | 1 |
| Skalweit, MJ | 1 |
| Nicolau, DP; Sutherland, CA | 2 |
| Huntington, JA; Miller, BW; Nicolau, DP; Xiao, AJ | 1 |
| Cho, JC; Estrada, SJ; Fiorenza, MA | 1 |
| Hirsch, EB; Liscio, JL; Mahoney, MV | 1 |
| Chahine, EB; Cogan, P; Fete, M; Sucher, AJ | 1 |
| Berrazeg, M; Broutin, I; Fournier, D; Jeannot, K; Loeffert, S; Ntsogo Enguéné, VY; Plésiat, P | 1 |
| Burnham, CA; Dubberke, ER; Gonzalez, MD; Hink, T; Wallace, MA | 1 |
| Bofarull, AM; Cantón, R; García-Castillo, M; Tato, M | 1 |
| Hussar, DA | 1 |
| Boyles, T | 1 |
| Kielstein, JT; Schmidt, JJ | 1 |
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| Eckmann, C; Hershberger, E; Solomkin, JS | 1 |
| Armstrong, ES; Farrell, DJ; Palchak, M; Steenbergen, JN | 1 |
| Bowker, KE; MacGowan, AP; Nicholls, D; Noel, AR; Tomaselli, SG | 1 |
| Gholipourmalekabadi, M; Hashemi, A; Mozafari, M; Rostami, A; Sameni, M; Zamani, F | 1 |
| Aamir, M; Abrol, P; Punia, H; Sharma, D | 1 |
| Fowler, RC; Geyer, CN; Hanson, ND; Hawkey, P; Johnson, JR; Johnston, B; Weissman, SJ | 1 |
| Cluck, D; Lewis, P; Moorman, J; Spivey, J; Stayer, B | 1 |
| Hsu, AJ; Tamma, PD; Tamma, SM | 1 |
| Geerlings, SE; Holleman, F; Schneeberger, C | 1 |
| Gonzales, JP; Heil, EL; Mehrotra, S; Nicolau, DP; Oliver, WD; Robinett, K; Saleeb, P | 1 |
| Bulman, ZP; Forrest, A; Friedrich, LV; Holden, PN; Kelchlin, P; Lenhard, JR; Soon, RL; Steenbergen, JN; Tsuji, BT | 1 |
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| Boyd, D; Carpenter, M; Desruisseau, A; Janecko, N; Mangat, CS; Martz, SL; Mulvey, MR; Reid-Smith, RJ | 1 |
| Bork, JT; D'Angelo, RG; Heil, EL; Johnson, JK | 1 |
| Cohen, H; Peyko, V; Smalley, S | 1 |
| Hammond, DA; Lusardi, K; Meena, NK; Painter, JT; Smith, MN | 1 |
| Alkrouk, A; Buehrle, DJ; Chen, L; Clancy, CJ; Hao, B; Kreiswirth, BN; Nguyen, MH; Potoski, BA; Press, EG; Shields, RK | 1 |
| Bliss, C; Cloutier, DJ; Goldstein, EJ; Huntington, JA; Sakoulas, G; Steenbergen, JN; Umeh, O | 1 |
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| Higuchi, H; Horikoshi, Y; Isogai, M; Ito, K; Shoji, T; Suwa, J | 1 |
| Alidjanov, JF; Wagenlehner, FM | 1 |
| Antony, S; Dominguez, DC; Soto-Ruiz, E; Teleb, M | 1 |
| Ghazi, IM; Kuti, JL; Nicolau, DP; Quintiliani, R; Shore, E | 1 |
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| Cies, JJ; Kuti, JL; Monogue, ML; Muhlebach, M; Nicolau, DP; Pettit, RS | 1 |
| Borgia, G; Gentile, I; Maraolo, AE | 1 |
| Chen, J; Kong, C; Zhang, Y; Zhu, L; Zou, X | 1 |
| Algora-Weber, A; de la Calle-Pedrosa, N; Delgado-Iribarren, A; Gabán-Díez, Á; González-Jiménez, AI; Hernández-Tejedor, A; Martín-Vivas, A; Merino-Vega, CD; Ruiz de Luna-González, R; Temprano-Gómez, I | 1 |
| Bliss, CA; Cloutier, D; Hershberger, E; Huntington, JA; Kaye, KS; Miller, B; Paterson, DL; Popejoy, MW; Steenbergen, JN; Umeh, O | 1 |
| Monogue, ML; Nicolau, DP | 1 |
| Armstrong, ES; Bliss, CA; Cloutier, DJ; Mikulca, JA; Steenbergen, JN | 1 |
| Burgess, DR; Burgess, DS; Cox, JN; Martin, CA; Rutter, WC | 1 |
| Baumert, P; Feihl, S; Gastmeier, P; Gebhardt, F; Gölz, H; Hamprecht, A; Kern, WV; Knobloch, J; Kola, A; Mischnik, A; Obermann, B; Peter, S; Querbach, C; Rohde, A; Seifert, H; Tacconelli, E; Willmann, M | 1 |
| Castón, JJ; De la Torre, Á; Ruiz-Camps, I; Sorlí, ML; Torre-Cisneros, J; Torres, V | 1 |
| Connor, KA | 1 |
| Evans, R; Hussain, T; Karino, S; Kaye, KS; Koons, J; Koppula, S; Martin, ET; Murray, KP; Mynatt, RP; Navalkele, B; Nishan, B; Perry, W; Pervaiz, A; Pogue, JM; Rybak, MJ; Salim, M; Shaikh, H; Solanki, S; Tashtoush, N | 1 |
| Goldstein, EJ; Kullar, R; Long, J; Popejoy, MW; Wagenlehner, FM; Yu, B | 1 |
| Crespo Casal, M; Martinez-Lamas, L; Nodar, A; Perez-Landeiro, A; Perez-Rodríguez, MT; Sousa Dominguez, A | 1 |
| Hamada, Y; Nicolau, DP; Thabit, AK | 1 |
| Burnham, CA; Crotty, MP; Gonzalez, MD; McMullen, AR; Ritchie, DJ; Wallace, MA | 1 |
| Hackel, MA; Hoban, DJ; Karlowsky, JA; Lob, SH; Sahm, DF | 1 |
| Lavigne, JP; Meiller, E; Merens, A; Nicolas-Chanoine, MH; Pantel, A; Robert, J | 1 |
| Compain, F; Grohs, P; Kaibi, I; Lavollay, M; Mainardi, JL; Morand, P; Podglajen, I; Taieb, G | 1 |
| Bassetti, M; Castanheira, M; Duncan, LR; Pfaller, MA | 1 |
| Chaijamorn, W; Lewis, SJ; Mueller, BA; Shaw, AR | 1 |
| Gao, L; Li, Y; Lyu, Y | 1 |
| Rademacher, J; Welte, T | 1 |
| Abbo, LM; Adachi, J; Aitken, SL; Araos, R; Arias, CA; Bonomo, RA; Jain, R; Lichtenberger, PN; Miller, WR; Munita, JM; Nigo, M; Perez, F; Rakita, R; Rosa, R; Shelburne, S; Shimose, LA; Tran, TT; Wanger, A | 1 |
| Álvarez Lerma, F; Gracia Arnillas, MP; Grau, S; Mico García, M; Muñoz Bermudez, R; Recasens, L; Sorli, L | 1 |
| Rodriguez-Bano, J; Tamma, PD | 1 |
| Berenson, CS; Kurtzhalts, KE; Manohar, A; Mergenhagen, KA | 1 |
| Li, B; Li, L; Peters, BM; Shirtliff, ME; Xie, J; Xu, Z; Yu, G | 1 |
| LeCleir, LK; Pettit, RS | 1 |
| Basu, A; Borse, RH; Gaultney, J; Kauf, TL; Medic, G; Miller, B; Prabhu, VS; Sen, SS | 1 |
| Huntington, JA; Long, J; Popejoy, MW | 1 |
| Castanheira, M; Flamm, RK; Pfaller, MA; Shortridge, D | 2 |
| Adkin, R; Chaudhry, A; Hill, R; Hopkins, KL; Livermore, DM; Meunier, D; Mushtaq, S; Pike, R; Staves, P; Woodford, N | 1 |
| Hincapie Castillo, J; Jeon, N; Klinker, KP; Staley, B; Winterstein, AG | 1 |
| Ahir, H; Foo, J; Merchant, S; Prabhu, V; Sarpong, E | 1 |
| Falagas, ME; Kofteridis, DP; Maraki, S; Mavromanolaki, VE; Perdikis, D; Samonis, G; Vardakas, KZ | 1 |
| Borgia, G; Buonomo, AR; De Zottis, F; Di Renzo, G; Gentile, I; Maraolo, AE; Scotto, R | 1 |
| Kim, HS; Kim, HY; Kim, YK; Lee, J; Lee, JA; Lee, SS; Seo, YB; Song, W; Uh, Y | 1 |
| Cabot, G; Del Barrio-Tofiño, E; Fraile-Ribot, PA; Juan, C; Mulet, X; Oliver, A; Pérez, JL | 1 |
| Davido, B; de Truchis, P; Dinh, A; Salomon, J; Senard, O | 1 |
| Alatoom, A | 1 |
| Cho, B; Chung, NG; Han, SB; Jeong, DC; Kang, JH; Kim, HS; Kim, SK; Lee, DG; Lee, JW; Park, BK | 1 |
| Grupper, M; Nicolau, DP; Sutherland, C | 1 |
| Cohen-Wolkowiez, M; Greenberg, RG; Rivera-Chaparro, ND | 1 |
| Burgess, DR; Burgess, DS; Cotner, SE; Martin, CA; Rutter, WC; Wallace, KL | 1 |
| Mueller, BA; Shaw, AR | 1 |
| Flamm, RK; Huband, MD; Jones, RN; Riedel, S; Sader, HS | 1 |
| Borgia, G; Cascella, M; Corcione, S; Cuomo, A; De Rosa, FG; Gentile, I; Maraolo, AE; Nappa, S | 1 |
| Anderson, KT; Kao, LS; Lally, KP; Mueck, KM; Putnam, LR; Tsao, K | 1 |
| Goodlet, KJ; Nailor, MD; Nicolau, DP | 1 |
| Sinkó, J | 1 |
| Chen, L; Kreiswirth, BN; MacVane, SH; Pandey, R; Steed, LL | 1 |
| Becker, K; Bletz, S; Idelevich, EA; Mellmann, A; Schaumburg, F | 1 |
| Bodro, M; Marco, F; Martínez, JA; Soriano, A; Xipell, M | 1 |
| Hindler, JA; Humphries, RM; Miller, SA; Wong-Beringer, A | 1 |
| Cheng, S; Clancy, CJ; Cooper, VS; Doi, Y; Haidar, G; Hao, B; Nguyen, MH; Philips, NJ; Potoski, BA; Press, EG; Shields, RK; Snyder, D | 1 |
| Livermore, DM; Mushtaq, S; Turner, SJ; Warner, M; Woodford, N | 1 |
| Bassetti, M; Castaldo, N; Givone, F; Lechiancole, A; Livi, U; Maiani, M; Pea, F; Peghin, M; Righi, E; Sartor, A | 1 |
| Lodise, TP; Natesan, S; Pai, MP | 1 |
| Arcenillas, P; Boix-Palop, L; Calbo, E; Cuchi, E; Dietl, B; Gómez, L; González de Molina, FJ; Nicolás, J; Sánchez, I | 1 |
| Bansal, N; Gopalakrishnan, R; Kumar D, S; Nambi, PS; Ramasubramanian, V; Sukhwani, KS | 1 |
| Bischoff, S; Ebert, M; Gerigk, M; Vogelmann, R; Walter, T | 1 |
| Fridrichová, M; Jakubů, V; Žemličková, H | 1 |
| Hakki, M; Lewis, JS | 1 |
| Girotto, JE; Nicolau, DP; Rodriguez, BA | 1 |
| Blasi, F; Downey, DG; Elborn, JS; Gramegna, A; Millar, BC; Moore, JE | 1 |
| Bertrand, X; Bouiller, K; Bouxom, H; Fournier, D; Hocquet, D | 1 |
| Almirante, B; Arévalo, Á; Campany, D; Escolà-Vergé, L; Ferrer, R; Larrosa, N; Len, O; Los-Arcos, I; Nuvials, X; Pigrau, C; Viñado, B | 1 |
| Chaves, F; Lora-Tamayo, J; Orellana, MÁ; Recio, R; Viedma, E; Villa, J | 1 |
| Aguilar-Aguilar, G; Alós-Almiñana, M; Belda-Nacher, JF; Carbonell, JA; Ezquer-Garin, C; Ferriols-Lisart, R | 1 |
| Finklea, JD; Hollaway, R; Jain, R; Le, J; Lee, F; Lowe, K | 1 |
| Hao, D; Hu, Z; Liu, X; Sun, T; Tian, H; Wang, T; Wang, X | 1 |
| Bonomo, RA; Davis, SL; Dhar, S; File, TM; Gerlach, AT; Kaye, KS; Olson, S; Patel, TS; Perez, F; Pogue, JM; Puzniak, LA; Veve, MP | 1 |
| Bardonneau, G; Biais, M; Carrié, C; Gruson, D; Ouattara, A; Pereira, B; Petit, L | 1 |
| Dorn, C; Eberl, S; Nussbaumer-Pröll, AK; Reiter, B; Stimpfl, T; Zeitlinger, M | 1 |
| Alimova, EE; Dibirov, MD; Isaev, AI; Karsotyan, GS; Khachatryan, NN; Kostyuk, EA | 1 |
| Carvalhaes, CG; Duncan, LR; Flamm, RK; Sader, HS; Shortridge, D | 1 |
| Forland, SC; Guerrero-Wooley, RL; Hino, G; Park, SH; Winans, SA | 1 |
| Murri, R; Sacco, E | 1 |
| Al Jalali, V; Dorn, C; Kratzer, A; Lackner, E; Matzneller, P; Österreicher, Z; Taubert, M; Wölfl-Duchek, M; Wulkersdorfer, B; Zeitlinger, M | 1 |
| Bremmer, DN; Kline, EG; Nicolau, DP; Shah, S; Shields, RK | 1 |
| Gillani, SW; Hussain, MW; Mahmood, RK; Rathore, HA; Saeed, MW; Vippadapu, P | 1 |
| Castanheira, M; Chen, WT; Pfaller, M; Shortridge, D; Streit, J; Tulloch, M | 1 |
| Ben-Zvi, H; Fanous, E; Herscovici, T; Kaplan, E; Livni, G; Mor, M; Schiller, O; Vardi, Y | 1 |
| Ashouri, N; Bensaci, M; Bradley, JS; Bruno, CJ; De Anda, C; Huntington, JA; Johnson, MG; Lonchar, J; Popejoy, MW; Rhee, EG; Roilides, E; Su, FH | 1 |
| Akrich, B; DeRyke, CA; Hawser, SP; Karlowsky, JA; Lob, SH; Motyl, MR; Sahm, DF; Siddiqui, F; Young, K | 1 |
| Bensaci, M; Bruno, CJ; De Anda, C; Dementieva, N; Huntington, JA; Jackson, CA; Johnson, MG; Lonchar, J; Newland, J; Popejoy, MW; Rhee, EG; Su, FH | 1 |
| Gilboa, M; van Duin, D; Yahav, D | 1 |
| Fujimori, T; Hagiya, H; Higashikage, A; Iio, K; Kakehi, A; Minabe, H; Okura, M; Otsuka, F; Yokoyama, Y | 1 |
| Ishizawa, T; Kimura, K; Kinoshita, M; Kubo, S; Nishio, K; Ohira, G; Okada, T; Shinkawa, H; Shirai, D; Tanaka, S; Tani, N; Tauchi, J | 1 |
| Bahrs, C; Bartonickova, L; Burgmann, H; Hagel, S; Paulussen, E; Pletz, MW; Schneider, L; Starzengruber, P; Tobudic, S | 1 |
44 review(s) available for cephalosporin c and penicillanic acid
| Article | Year |
|---|---|
beta-Lactam antibiotics and related substances.
Topics: Animals; Anti-Bacterial Agents; Bacteria; Bacterial Infections; beta-Lactams; Carboxypeptidases; Cephalosporinase; Cephalosporins; Drug Synergism; Humans; Hydrolases; Penicillanic Acid; Penicillin Resistance; Penicillinase; Penicillins; Staphylococcus; Streptomyces; Structure-Activity Relationship | 1977 |
Treatment of uncomplicated infections due to Neisseria gonorrhoeae. A review of clinical efficacy and in vitro susceptibility studies from 1982 through 1985.
Topics: Cephalosporins; Chlamydia Infections; Clavulanic Acid; Clavulanic Acids; Female; Gonorrhea; Humans; Male; Microbial Sensitivity Tests; Neisseria gonorrhoeae; Penicillanic Acid; Penicillin Resistance; Penicillins; Pharyngeal Diseases; Quinolines; Spectinomycin; Sulbactam; Syphilis; Tetracycline | 1986 |
Biosynthesis of peptide antibiotics.
Topics: Anti-Bacterial Agents; Aspergillus; Bacillus; Bacitracin; Cephalosporins; Chemical Phenomena; Chemistry; Dactinomycin; Methods; Penicillanic Acid; Penicillin G; Penicillins; Penicillium; Peptide Biosynthesis; Peptides, Cyclic; Piperazines; Polymyxins; Streptococcus; Streptomyces; Thiazines; Tyrothricin; Valinomycin | 1971 |
-lactam antibiotics: their physicochemical properties and biological activities in relation to structure.
Topics: Amides; beta-Lactamase Inhibitors; beta-Lactams; Cephalosporins; Drug Stability; Drug Synergism; Infrared Rays; Intestinal Absorption; Kinetics; Microbial Sensitivity Tests; Models, Structural; Penicillanic Acid; Penicillins; Solubility; Spectrum Analysis; Structure-Activity Relationship; Ultraviolet Rays | 1971 |
Newer beta-lactam antibiotics.
Topics: Acetamides; Amines; Ampicillin; Azepines; Azides; beta-Lactams; Carbenicillin; Carboxylic Acids; Cephalosporins; Cyclohexanes; In Vitro Techniques; Indenes; Mandelic Acids; Nitriles; Penicillanic Acid; Penicillin G; Penicillins; Pyridines; Sulfonic Acids; Tetrazoles; Thiadiazoles; Thiophenes; Valerates | 1974 |
Microbial penicillin acylases.
Topics: Actinomycetales; Amidohydrolases; Ampicillin; Bacteria; Biotransformation; Cephalosporins; Chemical Phenomena; Chemistry; Chromatography, Paper; Colorimetry; Fungi; Hydrolysis; Penicillanic Acid; Penicillin G; Penicillin V; Penicillinase; Penicillins; Spectrophotometry; Terminology as Topic; Yeasts | 1974 |
Thirthy years of penicillin therapy.
Topics: Animals; Autolysis; Bacterial Infections; Cephalosporins; Clostridium; Crystallography; Drug Stability; Escherichia coli; Guinea Pigs; History, 20th Century; Humans; Mice; Microbial Sensitivity Tests; Micrococcus; Muramidase; Penicillanic Acid; Penicillins; Penicillium; Rabbits; Salmonella; Streptococcal Infections | 1971 |
[Role of biocatalysis in the creation and improvement of production of beta-lactam antibiotics in Russia].
Topics: Anti-Bacterial Agents; Catalysis; Cephalosporins; Enzymes, Immobilized; Penicillanic Acid; Russia; Technology, Pharmaceutical | 1994 |
Production of 6-APA, 7-ACA, and 7-ADCA by immobilized penicillin and cephalosporin amidases.
Topics: Bacillus megaterium; Cephalosporinase; Cephalosporins; Enzymes, Immobilized; Industrial Microbiology; Penicillanic Acid; Penicillin Amidase | 1993 |
Piperacillin/tazobactam in the treatment of polymicrobial infections.
Topics: Aminoglycosides; Anti-Bacterial Agents; Bacterial Infections; beta-Lactamase Inhibitors; Cephalosporins; Drug Combinations; Drug Resistance, Microbial; Humans; Penicillanic Acid; Penicillins; Piperacillin; Tazobactam | 1994 |
Role of newer broad-spectrum beta-lactam and fluoroquinolone antibiotics in children.
Topics: Adolescent; Anti-Bacterial Agents; Anti-Infective Agents; Bacterial Infections; Carbapenems; Cephalosporins; Child; Child, Preschool; Clavulanic Acid; Clavulanic Acids; Drug Interactions; Drug Resistance, Microbial; Drug Therapy, Combination; Enzyme Inhibitors; Fluoroquinolones; Humans; Molecular Structure; Penicillanic Acid; Penicillins; Piperacillin; Tazobactam; Ticarcillin | 1996 |
Resistance to beta-lactam antibiotics: structure and mechanism based design of beta-lactamase inhibitors.
Topics: Anti-Bacterial Agents; beta-Lactam Resistance; beta-Lactamase Inhibitors; beta-Lactamases; Boronic Acids; Cephalosporins; Clavulanic Acids; Drug Design; Enzyme Inhibitors; Humans; Monobactams; Penicillanic Acid; Structure-Activity Relationship | 2002 |
The role of beta-lactam antimicrobials as single agents in treatment of intra-abdominal infection.
Topics: Abdomen; Abdominal Abscess; Ampicillin; Anti-Bacterial Agents; Bacterial Infections; beta-Lactamase Inhibitors; Carbapenems; Cephalosporins; Clavulanic Acids; Drug Resistance, Bacterial; Drug Therapy, Combination; Enzyme Inhibitors; Humans; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Sulbactam; Surgical Wound Infection; Ticarcillin | 2000 |
Role of pharmacodynamics in designing dosage regimens for beta-lactams.
Topics: Anti-Bacterial Agents; Cefepime; Cephalosporins; Dose-Response Relationship, Drug; Humans; Meropenem; Penicillanic Acid; Piperacillin; Tazobactam; Thienamycins | 2003 |
Cefotaximases (CTX-M-ases), an expanding family of extended-spectrum beta-lactamases.
Topics: beta-Lactamases; Cefotaxime; Cephalosporins; Clavulanic Acid; Drug Resistance, Bacterial; Enterobacteriaceae; Enzyme Inhibitors; Gene Transfer, Horizontal; Monobactams; Penicillanic Acid; Penicillins; Phylogeny; Sulbactam; Tazobactam | 2004 |
Empirical antibiotic monotherapy for febrile neutropenia: systematic review and meta-analysis of randomized controlled trials.
Topics: Anti-Bacterial Agents; beta-Lactamase Inhibitors; Carbapenems; Cefepime; Cephalosporins; Enzyme Inhibitors; Fever; Humans; Neutropenia; Penicillanic Acid; Penicillins; Quality Assurance, Health Care; Randomized Controlled Trials as Topic; Tazobactam; Treatment Outcome | 2006 |
Antimicrobial resistance in gram-positive bacteria.
Topics: Animals; beta-Lactamase Inhibitors; Cephalosporins; Community-Acquired Infections; Cross Infection; Drug Combinations; Drug Resistance, Bacterial; Enterococcus faecalis; Gastrointestinal Tract; Gram-Positive Bacteria; Gram-Positive Bacterial Infections; Humans; Methicillin Resistance; Penicillanic Acid; Piperacillin; Tazobactam; Vancomycin Resistance | 2006 |
The 50th anniversary of the discovery of 6-aminopenicillanic acid (6-APA).
Topics: Anti-Bacterial Agents; Bacterial Infections; beta-Lactamase Inhibitors; beta-Lactamases; beta-Lactams; Cephalosporins; Humans; Hydrolysis; Penicillanic Acid; Penicillins; Thienamycins | 2007 |
Anti-pseudomonal beta-lactams for the initial, empirical, treatment of febrile neutropenia: comparison of beta-lactams.
Topics: Anti-Bacterial Agents; beta-Lactams; Cefepime; Ceftazidime; Cephalosporins; Fever; Humans; Imipenem; Meropenem; Neutropenia; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Pseudomonas aeruginosa; Pseudomonas Infections; Randomized Controlled Trials as Topic; Thienamycins | 2010 |
Optimization of anti-pseudomonal antibiotics for cystic fibrosis pulmonary exacerbations: II. cephalosporins and penicillins.
Topics: Anti-Bacterial Agents; beta-Lactam Resistance; Cefepime; Ceftazidime; Cephalosporins; Clavulanic Acids; Cystic Fibrosis; Disease Progression; Drug Therapy, Combination; Humans; Microbial Sensitivity Tests; Penicillanic Acid; Penicillins; Piperacillin; Piperacillin, Tazobactam Drug Combination; Pseudomonas aeruginosa; Pseudomonas Infections; Ticarcillin | 2013 |
Liver abscess caused by multidrug-resistant Pseudomonas aeruginosa treated with colistin; a case report and review of the literature.
Topics: Aged; Anti-Bacterial Agents; Bacteremia; Cephalosporins; Cholangitis; Colistin; Drug Resistance, Multiple, Bacterial; Humans; Kidney; Liver Abscess, Pyogenic; Male; Microbial Sensitivity Tests; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Pseudomonas aeruginosa; Pseudomonas Infections | 2013 |
Ceftolozane/tazobactam: a novel cephalosporin/β-lactamase inhibitor combination with activity against multidrug-resistant gram-negative bacilli.
Topics: Animals; Anti-Bacterial Agents; Cephalosporins; Drug Resistance, Multiple, Bacterial; Drug Therapy, Combination; Gram-Negative Bacterial Infections; Humans; Penicillanic Acid; Tazobactam | 2014 |
Escherichia coli sequence type 131: epidemiology and challenges in treatment.
Topics: Anti-Bacterial Agents; beta-Lactamases; Carbapenems; Cephalosporins; Cystitis; Drug Resistance, Multiple, Bacterial; Escherichia coli; Escherichia coli Infections; Humans; Microbial Sensitivity Tests; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Sepsis; United States | 2014 |
Ceftolozane/tazobactam (CXA 201) for the treatment of intra-abdominal infections.
Topics: Anti-Bacterial Agents; beta-Lactamase Inhibitors; Cephalosporins; Drug Combinations; Enzyme Inhibitors; Humans; Intraabdominal Infections; Penicillanic Acid; Tazobactam | 2014 |
Ceftolozane/tazobactam for the treatment of complicated intra-abdominal infections.
Topics: Anti-Bacterial Agents; Cephalosporins; Clinical Trials, Phase III as Topic; Drug Combinations; Drug Resistance, Bacterial; Gram-Negative Bacterial Infections; Humans; Intraabdominal Infections; Penicillanic Acid; Tazobactam | 2015 |
Ceftolozane/Tazobactam (Zerbaxa)--a new intravenous antibiotic.
Topics: Administration, Intravenous; Animals; Anti-Bacterial Agents; Anti-Infective Agents, Urinary; beta-Lactamase Inhibitors; Cephalosporins; Clinical Trials as Topic; Humans; Intraabdominal Infections; Penicillanic Acid; Tazobactam; Urinary Tract Infections | 2015 |
Profile of ceftolozane/tazobactam and its potential in the treatment of complicated intra-abdominal infections.
Topics: Anti-Bacterial Agents; Cephalosporins; Drug Approval; Drug Resistance, Bacterial; Humans; Intraabdominal Infections; Penicillanic Acid; Tazobactam; United States; United States Food and Drug Administration | 2015 |
Ceftolozane/Tazobactam: A Novel Cephalosporin/β-Lactamase Inhibitor Combination.
Topics: Animals; Anti-Bacterial Agents; Bacteria, Anaerobic; beta-Lactamase Inhibitors; Cephalosporins; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Drug Resistance, Bacterial; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; Microbial Sensitivity Tests; Penicillanic Acid; Randomized Controlled Trials as Topic; Tazobactam | 2015 |
Ceftolozane/tazobactam and ceftazidime/avibactam: two novel β-lactam/β-lactamase inhibitor combination agents for the treatment of resistant Gram-negative bacterial infections.
Topics: Anti-Bacterial Agents; Azabicyclo Compounds; Ceftazidime; Cephalosporins; Clinical Trials as Topic; Drug Combinations; Drug Resistance, Bacterial; Enzyme Inhibitors; Gram-Negative Bacteria; Gram-Negative Bacterial Infections; Humans; Penicillanic Acid; Tazobactam | 2015 |
Ceftolozane/Tazobactam: A New Cephalosporin and β-Lactamase Inhibitor Combination.
Topics: Animals; Anti-Bacterial Agents; beta-Lactamase Inhibitors; Cephalosporins; Clinical Trials as Topic; Drug Combinations; Drug Interactions; Drug Resistance, Bacterial; Humans; Intraabdominal Infections; Mice; Penicillanic Acid; Pseudomonas Infections; Tazobactam; Urinary Tract Infections | 2015 |
New drugs 2015, part 3.
Topics: Acids, Carbocyclic; Benzoxazines; Boron Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cephalosporins; Cyclopentanes; Drug Approval; Drug Combinations; Drug Therapy; Glucagon-Like Peptides; Guanidines; Humans; Imidazoles; Immunoglobulin Fc Fragments; Interferon-beta; Isoquinolines; Penicillanic Acid; Polyethylene Glycols; Pyridines; Quinuclidines; Recombinant Fusion Proteins; Tazobactam; Triazoles; United States; United States Food and Drug Administration | 2015 |
Ceftolozane-tazobactam: A new-generation cephalosporin.
Topics: Animals; Anti-Bacterial Agents; beta-Lactamase Inhibitors; Cephalosporins; Chemistry, Pharmaceutical; Clinical Trials as Topic; Humans; Penicillanic Acid; Tazobactam | 2015 |
Febrile urinary tract infections: pyelonephritis and urosepsis.
Topics: Anti-Infective Agents, Urinary; Cephalosporins; Diabetes Complications; Fever; Humans; Immunocompromised Host; Levofloxacin; Penicillanic Acid; Pyelonephritis; Randomized Controlled Trials as Topic; Risk Factors; Sepsis; Tazobactam; Treatment Outcome; Urinary Tract Infections | 2016 |
Ceftolozane/Tazobactam: A Review in Complicated Intra-Abdominal and Urinary Tract Infections.
Topics: Anti-Bacterial Agents; Cephalosporins; Clinical Trials, Phase III as Topic; Humans; Intraabdominal Infections; Multicenter Studies as Topic; Penicillanic Acid; Tazobactam; Urinary Tract Infections | 2016 |
Treatment options for extended-spectrum beta-lactamase (ESBL) and AmpC-producing bacteria.
Topics: Anti-Bacterial Agents; Bacterial Proteins; beta-Lactamase Inhibitors; beta-Lactamases; beta-Lactams; Cefepime; Cephalosporins; Drug Resistance, Bacterial; Drug Therapy, Combination; Enterobacteriaceae; Enterobacteriaceae Infections; Gram-Negative Aerobic Bacteria; Gram-Negative Bacterial Infections; Humans; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination | 2016 |
Bloodstream infections in neutropenic cancer patients: A practical update.
Topics: Anti-Bacterial Agents; Bacteremia; Cefepime; Cephalosporins; Disease Management; Drug Resistance, Bacterial; Febrile Neutropenia; Fluoroquinolones; Gram-Negative Bacteria; Humans; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Pre-Exposure Prophylaxis; Risk Factors | 2016 |
Efficacy, pharmacokinetic and pharmacodynamic profile of ceftolozane + tazobactam in the treatment of complicated urinary tract infections.
Topics: Anti-Infective Agents, Urinary; Cephalosporins; Drug Administration Schedule; Drug Resistance, Multiple, Bacterial; Humans; Penicillanic Acid; Tazobactam; Urinary Tract Infections | 2016 |
[New antibiotics - standstill or progress].
Topics: Anti-Bacterial Agents; Azabicyclo Compounds; Bacterial Infections; Ceftaroline; Ceftazidime; Cephalosporins; Clinical Trials as Topic; Drug Approval; Drug Combinations; Drug Resistance, Multiple, Bacterial; Ephedrine; Humans; Macrolides; Methicillin-Resistant Staphylococcus aureus; Organophosphates; Oxazoles; Penicillanic Acid; Phenobarbital; Staphylococcal Infections; Tazobactam; Theophylline; Triazoles | 2017 |
The Use of Noncarbapenem β-Lactams for the Treatment of Extended-Spectrum β-Lactamase Infections.
Topics: Anti-Bacterial Agents; beta-Lactam Resistance; beta-Lactamase Inhibitors; beta-Lactamases; Cefepime; Cephalosporins; Cephamycins; Enterobacteriaceae; Enterobacteriaceae Infections; Humans; Microbial Sensitivity Tests; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Treatment Outcome | 2017 |
Antibiotic Dosing in Continuous Renal Replacement Therapy.
Topics: Anti-Bacterial Agents; Cefepime; Ceftazidime; Cephalosporins; Computer Simulation; Critical Illness; Humans; Levofloxacin; Meropenem; Microbial Sensitivity Tests; Monte Carlo Method; Penicillanic Acid; Piperacillin; Renal Replacement Therapy; Sepsis; Tazobactam; Thienamycins | 2017 |
Management of multidrug-resistant Pseudomonas aeruginosa in the intensive care unit: state of the art.
Topics: Anti-Bacterial Agents; Azabicyclo Compounds; Ceftazidime; Cephalosporins; Critical Illness; Disease Management; Drug Combinations; Drug Resistance, Multiple, Bacterial; Drug Therapy, Combination; Humans; Intensive Care Units; Penicillanic Acid; Pseudomonas aeruginosa; Pseudomonas Infections; Risk Factors; Tazobactam; Treatment Outcome | 2017 |
[Clinical aspects of severe infections caused by antibiotic-resistant Gram-negative bacteria. The Empire strikes back?]
Topics: Anti-Bacterial Agents; Azabicyclo Compounds; Ceftazidime; Cephalosporins; Drug Combinations; Drug Resistance, Multiple, Bacterial; Gram-Negative Bacterial Infections; Humans; Penicillanic Acid; Tazobactam | 2017 |
Ceftazidime/Avibactam and Ceftolozane/Tazobactam: Novel Therapy for Multidrug Resistant Gram Negative Infections in Children.
Topics: Anti-Bacterial Agents; Azabicyclo Compounds; Ceftazidime; Cephalosporins; Child; Drug Combinations; Drug Resistance, Multiple, Bacterial; Gram-Negative Bacterial Infections; Humans; Penicillanic Acid; Tazobactam; Treatment Outcome | 2018 |
A Meta-Analysis on Clinical Outcomes of Ceftolozane versus Piperacillin in Combination with Tazobactam in Patients with Complicated Urinary Tract Infections.
Topics: Anti-Bacterial Agents; Cephalosporins; Humans; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Pyelonephritis; Tazobactam; Urinary Tract Infections | 2022 |
41 trial(s) available for cephalosporin c and penicillanic acid
| Article | Year |
|---|---|
Comparison of pivmecillinam and cephradine in bacteriuria in pregnancy and in acute urinary tract infection.
Topics: Adult; Amdinocillin Pivoxil; Bacteriuria; Birth Weight; Cephalosporins; Cephradine; Clinical Trials as Topic; Female; Humans; Male; Penicillanic Acid; Pregnancy; Pregnancy Complications, Infectious; Time Factors; Urinary Tract Infections | 1979 |
Single dose doxycycline, cefuroxime and pivmecillinam for treatment of bacterial cystitis.
Topics: Administration, Oral; Adult; Amdinocillin Pivoxil; Anti-Infective Agents, Urinary; Bacterial Infections; Cefuroxime; Cephalosporins; Clinical Trials as Topic; Cystitis; Doxycycline; Drug Combinations; Female; Humans; Injections, Intramuscular; Middle Aged; Penicillanic Acid; Random Allocation; Recurrence; Sulfamethoxazole; Trimethoprim; Trimethoprim, Sulfamethoxazole Drug Combination | 1982 |
Randomized trial of cefamandole plus amdinocillin versus cefamandole in serious pediatric infections.
Topics: Amdinocillin; Bacterial Infections; Cefamandole; Cephalosporins; Child; Child, Preschool; Clinical Trials as Topic; Drug Synergism; Drug Therapy, Combination; Humans; Infant; Microbial Sensitivity Tests; Pediatrics; Penicillanic Acid; Random Allocation | 1983 |
Treatment of ventilator-associated pneumonia with piperacillin-tazobactam/amikacin versus ceftazidime/amikacin: a multicenter, randomized controlled trial. VAP Study Group.
Topics: Amikacin; Anti-Bacterial Agents; Ceftazidime; Cephalosporins; Consumer Product Safety; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Male; Middle Aged; Outcome Assessment, Health Care; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Pneumonia, Bacterial; Population; Treatment Failure; Ventilators, Mechanical | 1998 |
Piperacillin/tazobactam versus cefepime as initial empirical antimicrobial therapy in febrile neutropenic patients: a prospective randomized pilot study.
Topics: Anti-Infective Agents; Cefepime; Cephalosporins; Drug Therapy, Combination; Fever; Humans; Neutropenia; Penicillanic Acid; Pilot Projects; Piperacillin; Prognosis; Prospective Studies; Tazobactam | 1998 |
Neutropenic infections: a review of the French Febrile Aplasia Study Group trials in 608 febrile neutropenic patients.
Topics: Amikacin; Anti-Bacterial Agents; Ceftazidime; Cephalosporins; Ciprofloxacin; Drug Therapy, Combination; Fever; Hematologic Neoplasms; Humans; Multivariate Analysis; Neutropenia; Opportunistic Infections; Penicillanic Acid; Piperacillin; Tazobactam; Vancomycin | 1998 |
Piperacillin/tazobactam plus tobramycin versus ceftazidime plus tobramycin as empiric therapy for fever in severely neutropenic patients.
Topics: Adult; Anti-Bacterial Agents; Antineoplastic Agents; Bacteremia; Bacterial Infections; Case-Control Studies; Ceftazidime; Cephalosporins; Drug Resistance, Microbial; Drug Therapy, Combination; Enzyme Inhibitors; Female; Fever; Fever of Unknown Origin; Hematologic Neoplasms; Humans; Male; Middle Aged; Neutropenia; Penicillanic Acid; Penicillins; Piperacillin; Prospective Studies; Tazobactam; Tobramycin; Vancomycin | 1999 |
Antibiotic prophylaxis in percutaneous endoscopic gastrostomy (PEG): a prospective randomized clinical trial.
Topics: Antibiotic Prophylaxis; Cefotaxime; Cephalosporins; Endoscopy; Enteral Nutrition; Enzyme Inhibitors; Female; Gastrostomy; Humans; Incidence; Intubation, Gastrointestinal; Male; Middle Aged; Penicillanic Acid; Penicillins; Piperacillin; Prospective Studies; Surgical Wound Infection; Tazobactam | 1999 |
Efficacy and tolerability of piperacillin/tazobactam versus ceftazidime in association with amikacin for treating nosocomial pneumonia in intensive care patients: a prospective randomized multicenter trial.
Topics: Aged; Amikacin; Ceftazidime; Cephalosporins; Critical Care; Cross Infection; Drug Therapy, Combination; Female; Hospital Mortality; Hospitals, Teaching; Humans; Male; Middle Aged; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Pneumonia, Bacterial; Proportional Hazards Models; Prospective Studies; Spain; Survival Analysis; Treatment Outcome | 2001 |
A randomized prospective multicentre trial of cefpirome versus piperacillin-tazobactam in febrile neutropenia.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anemia, Aplastic; Cefpirome; Cephalosporins; Enzyme Inhibitors; Female; Fever; France; Hematologic Neoplasms; Humans; Male; Microbial Sensitivity Tests; Middle Aged; Myelodysplastic Syndromes; Neutropenia; Penicillanic Acid; Piperacillin; Tazobactam; Treatment Outcome | 2001 |
Cefepime plus amikacin versus piperacillin-tazobactam plus amikacin for initial antibiotic therapy in haematology patients with febrile neutropenia: results of an open, randomized, multicentre trial.
Topics: Adult; Amikacin; Anti-Bacterial Agents; Cefepime; Cephalosporins; Drug Therapy, Combination; Female; Fever; Hematologic Neoplasms; Hematopoietic Stem Cell Transplantation; Humans; Male; Neutropenia; Penicillanic Acid; Piperacillin; Tazobactam; Treatment Outcome | 2002 |
Efficacy of ertapenem in the treatment of serious infections caused by Enterobacteriaceae: analysis of pooled clinical trial data.
Topics: Adult; Aged; beta-Lactams; Ceftriaxone; Cephalosporins; Community-Acquired Infections; Double-Blind Method; Drug Therapy, Combination; Enterobacteriaceae Infections; Ertapenem; Escherichia coli Infections; Humans; Lactams; Middle Aged; Multicenter Studies as Topic; Penicillanic Acid; Piperacillin; Tazobactam; Treatment Outcome; Urinary Tract Infections | 2003 |
A randomized, open-label, multicenter comparative study of the efficacy and safety of piperacillin-tazobactam and cefepime for the empirical treatment of febrile neutropenic episodes in patients with hematologic malignancies.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Cefepime; Cephalosporins; Female; Fever; Hematologic Neoplasms; Hematopoietic Stem Cell Transplantation; Humans; Leukemia; Male; Middle Aged; Neutropenia; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Treatment Outcome | 2006 |
A prospective, randomized study comparing cefozopran with piperacillin-tazobactam plus ceftazidime as empirical therapy for febrile neutropenia in children with hematological disorders.
Topics: Adolescent; Anti-Bacterial Agents; beta-Lactamase Inhibitors; Cefozopran; Ceftazidime; Cephalosporins; Child; Child, Preschool; Drug Therapy, Combination; Female; Hematologic Neoplasms; Humans; Infant; Infant, Newborn; Male; Neutropenia; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Prognosis; Prospective Studies; Survival Rate | 2008 |
Piperacillin/tazobactam versus cefepime for the empirical treatment of pediatric cancer patients with neutropenia and fever: a randomized and open-label study.
Topics: Adolescent; Anti-Bacterial Agents; Cefepime; Cephalosporins; Child; Child, Preschool; Female; Fever; Humans; Infant; Male; Neutropenia; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Prospective Studies | 2009 |
Low-dose beta-lactam plus amikacin in febrile neutropenia: cefepime vs. piperacillin/tazobactam, a randomized trial.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amikacin; Anti-Bacterial Agents; Cefepime; Cephalosporins; Female; Fever of Unknown Origin; Humans; Incidence; Male; Middle Aged; Neutropenia; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Poisoning; Prospective Studies; Treatment Outcome; Young Adult | 2010 |
Piperacillin/tazobactam versus cefozopran for the empirical treatment of pediatric cancer patients with febrile neutropenia.
Topics: Adolescent; Anti-Bacterial Agents; Bacterial Infections; Cefozopran; Cephalosporins; Child; Child, Preschool; Female; Fever; Humans; Male; Neoplasms; Neutropenia; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination | 2011 |
Pharmacokinetics and safety of intravenous ceftolozane-tazobactam in healthy adult subjects following single and multiple ascending doses.
Topics: Administration, Oral; Adult; Aged; Anti-Bacterial Agents; Cephalosporins; Dose-Response Relationship, Drug; Female; Half-Life; Humans; Male; Middle Aged; Penicillanic Acid; Tazobactam; Young Adult | 2012 |
Intrapulmonary penetration of ceftolozane/tazobactam and piperacillin/tazobactam in healthy adult subjects.
Topics: Adult; Anti-Bacterial Agents; Bronchoalveolar Lavage Fluid; Cephalosporins; Female; Human Experimentation; Humans; Male; Middle Aged; Penicillanic Acid; Piperacillin; Plasma; Tazobactam; Time Factors; Young Adult | 2012 |
Prolonged infusion antibiotics for suspected gram-negative infections in the ICU: a before-after study.
Topics: Aged; Anti-Bacterial Agents; beta-Lactams; Cefepime; Cephalosporins; Cohort Studies; Cross Infection; Drug Administration Schedule; Female; Gram-Negative Bacteria; Gram-Negative Bacterial Infections; Hospitals, Teaching; Hospitals, Urban; Humans; Infusions, Intravenous; Intensive Care Units; Length of Stay; Male; Meropenem; Middle Aged; Missouri; Penicillanic Acid; Pilot Projects; Piperacillin; Piperacillin, Tazobactam Drug Combination; Thienamycins | 2013 |
Antibiotic rotation for febrile neutropenic patients with hematological malignancies: clinical significance of antibiotic heterogeneity.
Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Bacteremia; beta-Lactam Resistance; Cefepime; Cephalosporins; Ciprofloxacin; Drug Administration Schedule; Female; Fever; Gram-Negative Bacterial Infections; Hematologic Neoplasms; Humans; Male; Meropenem; Middle Aged; Neutropenia; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Prospective Studies; Thienamycins | 2013 |
Prophylactic first-line antibiotics reduce infectious fever and shorten hospital stay during chemotherapy-induced agranulocytosis in childhood acute myeloid leukemia.
Topics: Adolescent; Agranulocytosis; Anti-Bacterial Agents; Antineoplastic Combined Chemotherapy Protocols; Cefepime; Cephalosporins; Child; Child, Preschool; Female; Fever; Humans; Infection Control; Length of Stay; Leukemia, Myeloid, Acute; Male; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Prospective Studies; Vancomycin | 2014 |
Multicenter, double-blind, randomized, phase II trial to assess the safety and efficacy of ceftolozane-tazobactam plus metronidazole compared with meropenem in adult patients with complicated intra-abdominal infections.
Topics: Cephalosporins; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Infusions, Intravenous; Intraabdominal Infections; Male; Meropenem; Metronidazole; Middle Aged; Penicillanic Acid; Tazobactam; Thienamycins; Treatment Outcome | 2014 |
Population pharmacokinetics of ceftolozane/tazobactam in healthy volunteers, subjects with varying degrees of renal function and patients with bacterial infections.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Bacterial Infections; Cephalosporins; Female; Healthy Volunteers; Humans; Male; Middle Aged; Models, Biological; Penicillanic Acid; Renal Insufficiency; Tazobactam; Young Adult | 2015 |
Comparison between piperacillin/tazobactam and cefepime monotherapies as an empirical therapy for febrile neutropenia in children with hematological and malignant disorders: A prospective, randomized study.
Topics: Adolescent; Adult; Anti-Bacterial Agents; Bacterial Infections; Cefepime; Cephalosporins; Child; Child, Preschool; Febrile Neutropenia; Female; Hematologic Neoplasms; Humans; Infant; Infant, Newborn; Male; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Prospective Studies; Young Adult | 2015 |
Ceftolozane/Tazobactam Plus Metronidazole for Complicated Intra-abdominal Infections in an Era of Multidrug Resistance: Results From a Randomized, Double-Blind, Phase 3 Trial (ASPECT-cIAI).
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Bacterial Infections; Cephalosporins; Double-Blind Method; Drug Resistance, Multiple, Bacterial; Drug Therapy, Combination; Female; Humans; Intraabdominal Infections; Male; Metronidazole; Middle Aged; Penicillanic Acid; Prospective Studies; Tazobactam; Treatment Outcome; Young Adult | 2015 |
Ceftolozane-tazobactam compared with levofloxacin in the treatment of complicated urinary-tract infections, including pyelonephritis: a randomised, double-blind, phase 3 trial (ASPECT-cUTI).
Topics: Adult; Aged; Anti-Infective Agents, Urinary; Cephalosporins; Double-Blind Method; Drug Administration Schedule; Female; Gram-Negative Bacterial Infections; Gram-Positive Bacterial Infections; Humans; Infusions, Intravenous; Levofloxacin; Male; Middle Aged; Penicillanic Acid; Pyelonephritis; Tazobactam; Treatment Outcome; Urinary Tract Infections; Young Adult | 2015 |
Ceftolozane/tazobactam pharmacokinetic/pharmacodynamic-derived dose justification for phase 3 studies in patients with nosocomial pneumonia.
Topics: Adult; Anti-Bacterial Agents; Bronchoalveolar Lavage Fluid; Cephalosporins; Cross Infection; Drug Combinations; Female; Humans; Male; Microbial Sensitivity Tests; Middle Aged; Models, Biological; Monte Carlo Method; Penicillanic Acid; Pneumonia; Tazobactam; Young Adult | 2016 |
In Vitro Activity of Ceftolozane-Tazobactam against Anaerobic Organisms Identified during the ASPECT-cIAI Study.
Topics: Anaerobiosis; Anti-Bacterial Agents; Bacteroides; Bacteroides fragilis; Bacteroides Infections; Cephalosporins; Drug Therapy, Combination; Gram-Positive Bacteria; Gram-Positive Bacterial Infections; Humans; Intraabdominal Infections; Metronidazole; Microbial Sensitivity Tests; Penicillanic Acid; Tazobactam | 2016 |
A clinical evaluation of efficacy and safety of cefepime monotherapy versus piperacillin-tazobactam in patients of paediatric age group with febrile neutropenia in a tertiary care centre of north India.
Topics: Adolescent; Anti-Bacterial Agents; Bacterial Infections; Cefepime; Cephalosporins; Child; Child, Preschool; Drug Therapy, Combination; Febrile Neutropenia; Female; Fever; Humans; India; Male; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Prospective Studies; Tertiary Care Centers; Treatment Outcome | 2016 |
Efficacy of ceftolozane/tazobactam versus levofloxacin in the treatment of complicated urinary tract infections (cUTIs) caused by levofloxacin-resistant pathogens: results from the ASPECT-cUTI trial.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; beta-Lactamase Inhibitors; Cephalosporins; Double-Blind Method; Drug Resistance, Bacterial; Enterobacteriaceae Infections; Female; Humans; Levofloxacin; Male; Microbial Sensitivity Tests; Middle Aged; Penicillanic Acid; Tazobactam; Treatment Outcome; Urinary Tract Infections; Young Adult | 2016 |
Characteristics and Outcomes of Complicated Intra-abdominal Infections Involving Pseudomonas aeruginosa from a Randomized, Double-Blind, Phase 3 Ceftolozane-Tazobactam Study.
Topics: Adult; Aged; Anti-Bacterial Agents; Cephalosporins; Double-Blind Method; Female; Humans; Intraabdominal Infections; Male; Metronidazole; Middle Aged; Penicillanic Acid; Pseudomonas aeruginosa; Tazobactam | 2016 |
Population Pharmacokinetics and Safety of Ceftolozane-Tazobactam in Adult Cystic Fibrosis Patients Admitted with Acute Pulmonary Exacerbation.
Topics: Acute Disease; Adolescent; Adult; Anti-Bacterial Agents; Cephalosporins; Cystic Fibrosis; Female; Humans; Infusions, Intravenous; Lung; Male; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Middle Aged; Monte Carlo Method; Patient Safety; Penicillanic Acid; Pneumonia, Bacterial; Prospective Studies; Pseudomonas aeruginosa; Pseudomonas Infections; Staphylococcal Infections; Tazobactam | 2016 |
Efficacy of ceftolozane/tazobactam against urinary tract and intra-abdominal infections caused by ESBL-producing Escherichia coli and Klebsiella pneumoniae: a pooled analysis of Phase 3 clinical trials.
Topics: Administration, Intravenous; Adolescent; Adult; Aged; Aged, 80 and over; Anti-Infective Agents, Urinary; beta-Lactamase Inhibitors; beta-Lactamases; Cephalosporins; Double-Blind Method; Escherichia coli; Escherichia coli Infections; Female; Genotype; Humans; Intraabdominal Infections; Klebsiella Infections; Klebsiella pneumoniae; Levofloxacin; Male; Meropenem; Metronidazole; Middle Aged; Penicillanic Acid; Tazobactam; Thienamycins; Treatment Outcome; Urinary Tract Infections; Young Adult | 2017 |
Outcomes of high-dose levofloxacin therapy remain bound to the levofloxacin minimum inhibitory concentration in complicated urinary tract infections.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Infective Agents, Urinary; Cephalosporins; Dose-Response Relationship, Drug; Drug Administration Schedule; Enterobacteriaceae Infections; Female; Follow-Up Studies; Humans; Injections, Intravenous; Levofloxacin; Male; Microbial Sensitivity Tests; Middle Aged; Penicillanic Acid; Recurrence; Tazobactam; Treatment Outcome; Urinary Tract Infections; Young Adult | 2016 |
Does moderate renal impairment affect clinical outcomes in complicated intra-abdominal and complicated urinary tract infections? Analysis of two randomized controlled trials with ceftolozane/tazobactam.
Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; Cephalosporins; Female; Humans; Intraabdominal Infections; Male; Middle Aged; Penicillanic Acid; Renal Insufficiency; Tazobactam; Treatment Outcome; Urinary Tract Infections; Young Adult | 2017 |
Analysis of patients with diabetes and complicated intra-abdominal infection or complicated urinary tract infection in phase 3 trials of ceftolozane/tazobactam.
Topics: Adult; Aged; Anti-Bacterial Agents; Bacterial Infections; Cephalosporins; Diabetes Complications; Diabetes Mellitus; Female; Humans; Intraabdominal Infections; Levofloxacin; Male; Metronidazole; Middle Aged; Penicillanic Acid; Pyelonephritis; Tazobactam; Urinary Tract Infections | 2017 |
Randomized controlled trial of piperacillin-tazobactam, cefepime and ertapenem for the treatment of urinary tract infection caused by extended-spectrum beta-lactamase-producing Escherichia coli.
Topics: Aged; Aged, 80 and over; Anti-Bacterial Agents; beta-Lactamase Inhibitors; beta-Lactamases; beta-Lactams; Cefepime; Cephalosporins; Cross Infection; Ertapenem; Escherichia coli; Escherichia coli Infections; Female; Genotype; Humans; Male; Middle Aged; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Prospective Studies; Republic of Korea; Tazobactam; Urinary Tract Infections | 2017 |
Safety and Efficacy of Ceftolozane/Tazobactam Versus Meropenem in Neonates and Children With Complicated Urinary Tract Infection, Including Pyelonephritis: A Phase 2, Randomized Clinical Trial.
Topics: Adult; Anti-Bacterial Agents; Cephalosporins; Child; Escherichia coli; Humans; Infant, Newborn; Meropenem; Penicillanic Acid; Pyelonephritis; Tazobactam; Urinary Tract Infections | 2023 |
Safety and Efficacy of Ceftolozane/Tazobactam Plus Metronidazole Versus Meropenem From a Phase 2, Randomized Clinical Trial in Pediatric Participants With Complicated Intra-abdominal Infection.
Topics: Adult; Anti-Bacterial Agents; Cephalosporins; Child; Escherichia coli; Humans; Intraabdominal Infections; Meropenem; Metronidazole; Penicillanic Acid; Tazobactam | 2023 |
Which trial do we need? How to treat Pseudomonas aeruginosa bacteraemia-proposal for an umbrella randomized controlled trial.
Topics: Anti-Bacterial Agents; Bacteremia; Ceftazidime; Cephalosporins; Humans; Microbial Sensitivity Tests; Penicillanic Acid; Pseudomonas aeruginosa; Pseudomonas Infections | 2023 |
306 other study(ies) available for cephalosporin c and penicillanic acid
| Article | Year |
|---|---|
[Solubility and the complex-forming properties of the zwitterlytes, 6-aminopenicillanic and 7-aminodesacetoxycephalosporanic acids].
Topics: Cephalosporins; Chelating Agents; Chemical Phenomena; Chemistry, Physical; Drug Interactions; Hydrogen-Ion Concentration; Ions; Mathematics; Penicillanic Acid; Penicillin G; Solubility | 1979 |
Antigenic properties of polymers formed by beta-lactam antibiotics.
Topics: Ampicillin; Animals; Antigens; beta-Lactams; Cephalosporins; Epitopes; Guinea Pigs; Haplorhini; Papio; Passive Cutaneous Anaphylaxis; Penicillanic Acid; Penicillin G; Polymers; Rabbits; Skin Tests | 1976 |
[Biological properties of some new antibacterial antibiotics. I. Activities of some derivatives of 6-aminopenicillanic acid (6-AP) and 7-aminocephallosporanic acid (7-AC)].
Topics: Bacteria; Cephalosporins; Drug Resistance, Microbial; Penicillanic Acid | 1975 |
Transformations of penicillins: reactions of penam S-oxides with N-chloro-N-sodiocarbamates.
Topics: Carbamates; Cephalosporins; Chemical Phenomena; Chemistry; Cyclic S-Oxides; Penicillanic Acid | 1977 |
Preparation, identification, and quantitative NMR determination of silyl derivatives of 6-aminopenicillanic acid, 7-amino-3-methyl-delta3-cephem-4-carboxylic acid, and 7-amino-3-acetoxymethyl-delta3-cephem-4-carboxylic acid.
Topics: Cephalosporins; Isomerism; Magnetic Resonance Spectroscopy; Penicillanic Acid; Trimethylsilyl Compounds | 1977 |
GLC determination of 6-aminopenicillanic acid and 7-amino-3-methyl-delta3-cephem-4-carboxylic acid.
Topics: Cephalosporins; Chromatography, Gas; Penicillanic Acid; Trimethylsilyl Compounds | 1977 |
beta-Lactamase and beta-lactam antibiotics resistance in acinetobacter anitratum (syn: A. calcoaceticus).
Topics: Acinetobacter; Amidohydrolases; Cephaloridine; Cephalosporinase; Cephalosporins; Enzyme Induction; Penicillanic Acid; Penicillin Resistance; Penicillins | 1977 |
Escherichia coli resistance to beta-lactam antibiotics through a decrease in the affinity of a target for lethality.
Topics: Amdinocillin; Carrier Proteins; Cephalosporins; Chromosome Mapping; Escherichia coli; Mutation; Penicillanic Acid; Penicillin Resistance; Penicillins; Temperature | 1978 |
6-APA and the development of the beta-lactam antibiotics.
Topics: Anti-Bacterial Agents; beta-Lactamases; beta-Lactams; Cephalosporins; Chemistry; Drug Stability; History, 20th Century; Penicillanic Acid; Penicillin Resistance; Penicillins | 1979 |
[Spectrophotometric determination of the dihydrolutidine derivatives of cephalosporanic acids and penicillanic acids containing a primary amino group].
Topics: Cephalosporins; Methods; Penicillanic Acid; Spectrophotometry, Ultraviolet | 1979 |
In vitro combination of mecillinam with cephradine or amoxycillin for organisms resistant to single agents.
Topics: Amdinocillin; Amoxicillin; Bacteria; Cephalosporins; Cephradine; Drug Synergism; Humans; Microbial Sensitivity Tests; Penicillanic Acid; Penicillin Resistance; Urinary Tract Infections | 1979 |
Beta-lactamases from Yersinia enterocolitica.
Topics: Amidohydrolases; Cell-Free System; Cephalosporinase; Cephalosporins; Cloxacillin; Enzyme Induction; Enzyme Inhibitors; Hydrogen-Ion Concentration; Hydrolysis; Isoelectric Focusing; Molecular Weight; Penicillanic Acid; Penicillinase; Penicillins; Species Specificity; Sulfhydryl Reagents; Yersinia | 1975 |
Evaluation of antibiotic efficacy using electron microscopy: morphological effects of guanylureido cephalosporin, chlorobenzoylureido cephalosporin, BL-P1654, and carbenicillin on Pseudomonas aeruginosa.
Topics: Animals; Carbenicillin; Cephalosporins; Chlorobenzoates; Guanidines; Leucine; Mice; Microbial Sensitivity Tests; Microscopy, Electron, Scanning; Penicillanic Acid; Penicillins; Pseudomonas aeruginosa; Pseudomonas Infections | 1976 |
Synthesis and antibacterial activity of new ureido-beta-lactam derivatives having dialkyloxyphosphoryl-2-oxo-imidazolidinyl moieties.
Topics: Bacteria; Cephalosporins; Gram-Negative Bacteria; Gram-Positive Bacteria; Imidazoles; Magnetic Resonance Spectroscopy; Organophosphorus Compounds; Penicillanic Acid; Spectrophotometry, Infrared | 1992 |
beta-Lactamase inhibiting properties of 6-oxopenicillanic and 7-oxo-cephalosporanic acid derivatives.
Topics: Anti-Bacterial Agents; Bacillus cereus; beta-Lactamase Inhibitors; Cephalosporins; Enterobacter; Microbial Sensitivity Tests; Penicillanic Acid | 1991 |
Characterization of a beta-lactamase produced by Pseudomonas paucimobilis.
Topics: beta-Lactamase Inhibitors; beta-Lactamases; Cephalosporins; Chromosomes, Bacterial; Clavulanic Acid; Clavulanic Acids; Drug Resistance, Microbial; Molecular Weight; Penicillanic Acid; Penicillin Resistance; Penicillins; Pseudomonas; Sulbactam; Tazobactam | 1991 |
In vitro activity and stability against novel beta-lactamases of investigational beta-lactams (cefepime, cefpirome, flomoxef, SCE2787 and piperacillin plus tazobactam) in comparison with established compounds (cefotaxime, latamoxef and piperacillin).
Topics: Anti-Bacterial Agents; beta-Lactamases; Cefotaxime; Cefozopran; Cefpirome; Cephalosporins; Drug Stability; Enterobacteriaceae; Hydrolysis; Microbial Sensitivity Tests; Moxalactam; Penicillanic Acid; Piperacillin; Tazobactam | 1991 |
Beta-lactamases as fully efficient enzymes. Determination of all the rate constants in the acyl-enzyme mechanism.
Topics: Acylation; Bacillus cereus; beta-Lactamase Inhibitors; beta-Lactamases; Cephalosporins; Chemical Phenomena; Chemistry; Deuterium; Escherichia coli; Hydrolysis; Kinetics; Penicillanic Acid; Penicillin G; Staphylococcus aureus; Substrate Specificity | 1990 |
In vitro activity of cefepime, a new parenteral cephalosporin, against recent European blood isolates and in comparison with piperacillin/tazobactam.
Topics: beta-Lactamase Inhibitors; beta-Lactamases; Cefepime; Cephalosporins; Drug Resistance, Microbial; Drug Synergism; Enterobacteriaceae; Gram-Negative Bacteria; Microbial Sensitivity Tests; Penicillanic Acid; Penicillin Resistance; Piperacillin; Staphylococcus; Tazobactam | 1990 |
Investigation into the immunologic cross-reactivity of aztreonam with other beta-lactam antibiotics.
Topics: Adult; Aged; Anti-Bacterial Agents; Antibody Affinity; Antibody Formation; Aztreonam; Benzeneacetamides; Cephalosporins; Cross Reactions; Drug Hypersensitivity; Epitopes; Female; Humans; Immune Sera; Immunoglobulin E; Immunoglobulin G; Male; Middle Aged; Penicillanic Acid; Penicillins; Polylysine; Radioimmunoassay; Skin Tests | 1985 |
[Studies on ampicillin and amoxicillin derivatives. III. Synthesis of 6-[2-[(pyrido[2,3-d]pyrimidin-6-yl)methylamino]-2- phenylacetamido]-penicillanic acid derivatives, 6-[2-(4-pyrimidinylamino)-2-phenylacetamido]penicillanic acid derivatives and -cephalo
Topics: Bacteria; Cephalosporins; Drug Resistance, Microbial; Penicillanic Acid; Pyridines; Pyrimidines; Structure-Activity Relationship | 1987 |
Dissemination of the novel plasmid-mediated beta-lactamase CTX-1, which confers resistance to broad-spectrum cephalosporins, and its inhibition by beta-lactamase inhibitors.
Topics: beta-Lactamase Inhibitors; beta-Lactamases; Cephalosporins; Clavulanic Acids; DNA, Bacterial; Drug Resistance, Microbial; Drug Synergism; Enterobacteriaceae; Genes, Bacterial; Humans; Nucleic Acid Hybridization; Penicillanic Acid; Penicillin Resistance; Penicillins; R Factors; Sulbactam; Tazobactam | 1988 |
Inhibition of class C beta-lactamases by (1'R,6R)-6-(1'-hydroxy)benzylpenicillanic acid SS-dioxide.
Topics: beta-Lactamase Inhibitors; Cephalosporins; Hydrogen-Ion Concentration; Hydroxylamine; Hydroxylamines; Kinetics; Penicillanic Acid; Pseudomonas aeruginosa; Spectrophotometry | 1985 |
The in-vitro activity of a novel penem FCE 22101 compared to other beta-lactam antibiotics.
Topics: Anti-Bacterial Agents; Bacteria; beta-Lactamase Inhibitors; beta-Lactamases; Carbapenems; Cephalosporins; Gram-Negative Bacteria; Imipenem; Microbial Sensitivity Tests; Penicillanic Acid; Thienamycins | 1985 |
In vitro antimicrobial activity of cefoperazone-sulbactam combinations against 554 clinical isolates including a review and beta-lactamase studies.
Topics: Bacteria; Bacterial Infections; beta-Lactamase Inhibitors; beta-Lactamases; Cefoperazone; Cephalosporins; Drug Combinations; Humans; Microbial Sensitivity Tests; Penicillanic Acid; Sulbactam | 1985 |
Sensitivity of 115 strains of the genus Brucella to some antibiotics (cephalosporins, ureidopenicillins and aminoglycosides).
Topics: Aminoglycosides; Anti-Bacterial Agents; Brucella; Cephalosporins; Microbial Sensitivity Tests; Penicillanic Acid; Penicillins | 1986 |
Antibodies against the benzylpenicilloyl moiety as a probe for penicillin-binding proteins.
Topics: Animals; Antibodies; Bacillus subtilis; Bacterial Proteins; Carboxypeptidases; Carrier Proteins; Cephalosporins; Cross Reactions; Enzyme-Linked Immunosorbent Assay; Escherichia coli; Hexosyltransferases; Immunosorbent Techniques; Methods; Muramoylpentapeptide Carboxypeptidase; Penicillanic Acid; Penicillin G; Penicillin-Binding Proteins; Peptidyl Transferases; Rabbits; Streptococcus pneumoniae | 1986 |
The role of beta-lactamase in staphylococcal resistance to penicillinase-resistant penicillins and cephalosporins.
Topics: beta-Lactamase Inhibitors; beta-Lactamases; Cephalosporins; Cephalothin; Clavulanic Acid; Clavulanic Acids; Methicillin; Microbial Sensitivity Tests; Oxacillin; Penicillanic Acid; Penicillin Resistance; Penicillinase; Penicillins; Staphylococcus aureus; Sulbactam | 1986 |
Inactivation of D-alanine carboxypeptidase by penicillins and cephalosporins is not lethal in Bacillus subtilis.
Topics: Alanine; Bacillus subtilis; Carboxypeptidases; Cephalosporins; Cephalothin; Cloxacillin; Factor Analysis, Statistical; Hydrogen-Ion Concentration; Microbial Sensitivity Tests; Mutation; Penicillanic Acid; Penicillins; Peptidoglycan; Structure-Activity Relationship; Time Factors | 1971 |
Mutations that affect antibiotic synthesis by Cephalosporium acremonium.
Topics: Acremonium; Adipates; Biological Assay; Carbon Isotopes; Cephalosporins; Chromatography, Paper; Culture Media; Cysteine; Lactams; Lysine; Mutation; Penicillanic Acid; Penicillins; Peptide Biosynthesis; Phenotype; Pipecolic Acids; Time Factors; Valine | 1972 |
[Conversion of penicillins into cephalosporins].
Topics: Cephalosporins; Chemical Phenomena; Chemistry; Methods; Penicillanic Acid; Penicillins | 1972 |
[Improvement of technological processes in the production of 6-aminopenicillanic acid (6-APA)].
Topics: Cephalosporins; Methods; Penicillanic Acid; Penicillins; Thiazoles | 1972 |
[Determination of ampicillin, cephalexin and related compounds by formol titration. 7. Condensated acetidinones].
Topics: Ampicillin; Cephalexin; Cephalosporins; Chemical Phenomena; Chemistry; Formaldehyde; Methods; Penicillanic Acid | 1972 |
Preparation of 7-aminocephalosporanic acid and 6-aminopenicillanic acid.
Topics: Cephalosporins; Cephalothin; Chemical Phenomena; Chemistry; Penicillanic Acid; Penicillins; Thiazoles | 1972 |
Five penicillin-binding components occur in Bacillus subtilis membranes.
Topics: Alanine; Amino Acids; Bacillus subtilis; Bacterial Proteins; Binding Sites; Binding, Competitive; Carbon Isotopes; Carboxypeptidases; Cell Membrane; Cephalosporins; Electrophoresis, Polyacrylamide Gel; Fluorine; Kinetics; Penicillanic Acid; Penicillin G; Penicillins; Protein Binding; Sodium Dodecyl Sulfate; Stereoisomerism; Sulfonic Acids | 1972 |
Interactions of bovine serum albumin with penicillins and cephalosporins studied by pulse radiolysis.
Topics: Animals; Binding Sites; Cattle; Cephalosporins; Clofibrate; Cloxacillin; Disulfides; Electrons; Lysine; Palmitic Acids; Penicillanic Acid; Penicillin G; Penicillin V; Penicillins; Protein Conformation; Radiation Effects; Serum Albumin, Bovine; Structure-Activity Relationship | 1973 |
Purification and properties of -lactamase of pseudomonas aeruginosa.
Topics: Cephalosporins; Chromatography; Culture Media; Hydrogen-Ion Concentration; In Vitro Techniques; Methods; Penicillanic Acid; Penicillin Resistance; Penicillins; Pseudomonas aeruginosa; Temperature; Time Factors | 1972 |
Quaternary heterocyclylamino beta-lactams. IV. Comparison of the in vivo antibacterial activities of L-640,876, mecillinam, cefoxitin and cefotaxime.
Topics: Amdinocillin; Animals; Anti-Bacterial Agents; Cefotaxime; Cefoxitin; Cephalosporins; Gram-Negative Bacteria; Kinetics; Mice; Microbial Sensitivity Tests; Penicillanic Acid; Sepsis; Tissue Distribution | 1983 |
In vitro evaluation of new penicillins and cephalosporins upon P. aeruginosa and their interaction with mecillinam.
Topics: Amdinocillin; Azlocillin; Carbenicillin; Cefamandole; Cefoxitin; Cefsulodin; Cefuroxime; Cephalosporins; Culture Media; Drug Synergism; Mezlocillin; Penicillanic Acid; Penicillins; Pseudomonas aeruginosa; Pyocins; Ticarcillin | 1980 |
Spectrophotometric determination of inhibitory effects of CP-45899 on beta-lactamase with benzylpenicillin and nitrocefin.
Topics: Bacillus cereus; beta-Lactamase Inhibitors; beta-Lactamases; Cephalosporins; Cytochrome c Group; Hydrolysis; Oxidation-Reduction; Penicillanic Acid; Penicillin G; Spectrophotometry; Sulbactam | 1980 |
Sensitivities of clinically significant organisms to four cephalosporins, ampicillin and mecillinam.
Topics: Amdinocillin; Ampicillin; Bacterial Infections; Cefamandole; Cefoxitin; Cefuroxime; Cephalexin; Cephalosporins; Humans; Microbial Sensitivity Tests; Penicillanic Acid | 1980 |
Effect of combination of cefsulodin and mecillinam.
Topics: Amdinocillin; Animals; Bacteria; Bacterial Infections; Cefsulodin; Cephalosporins; Drug Synergism; Drug Therapy, Combination; Male; Mice; Penicillanic Acid; Serratia marcescens; Species Specificity | 1981 |
Plasmid-mediated partial cross-resistance between ampicillin, mecillinam and cefamandole in Salmonella johannesburg and Salmonella typhimurium.
Topics: Amdinocillin; Ampicillin; Cefamandole; Cephalosporins; Penicillanic Acid; Penicillin Resistance; Plasmids; Salmonella; Salmonella typhimurium | 1981 |
Synergistic activity of cefoperazone in combination with beta-lactamase inhibitors.
Topics: Anti-Bacterial Agents; Bacteria; beta-Lactamase Inhibitors; beta-Lactams; Cefoperazone; Cefotaxime; Cephalosporins; Clavulanic Acid; Drug Synergism; Penicillanic Acid; Sulbactam | 1981 |
Bactericidal activity of cefoperazone with CP-45,899 against large inocula of beta-lactamase-producing Haemophilus influenzae.
Topics: Anti-Bacterial Agents; beta-Lactamase Inhibitors; beta-Lactamases; Cefoperazone; Cephalosporins; Drug Synergism; Haemophilus influenzae; Penicillanic Acid; Sulbactam | 1981 |
Interaction of beta-lactamase of Streptomyces cacaoi. II. CP-45,899, izumenolide and cephamycins.
Topics: Anti-Bacterial Agents; beta-Lactamase Inhibitors; Cephalosporins; Cephamycins; Lactones; Penicillanic Acid; Streptomyces; Sulbactam | 1981 |
Interaction between non-classical beta-lactam compounds and the Zn2+-containing G and serine R61 and R39 D-alanyl-D-alanine peptidases.
Topics: Actinomycetaceae; Amdinocillin; beta-Lactams; Carboxypeptidases; Cefoxitin; Cephalosporins; Clavulanic Acid; Drug Interactions; Endopeptidases; Enzyme Inhibitors; Imipenem; Kinetics; Penicillanic Acid; Penicillins; Quinoxalines; Serine-Type D-Ala-D-Ala Carboxypeptidase; Streptomyces; Zinc | 1981 |
In vitro activity of moxalactam and mecillinam, singly and in combination, against multi-drug-resistant Enterobacteriaceae and Pseudomonas species.
Topics: Amdinocillin; Anti-Bacterial Agents; Cephalosporins; Cephamycins; Drug Interactions; Enterobacteriaceae; Microbial Sensitivity Tests; Moxalactam; Penicillanic Acid; Penicillin Resistance; Pseudomonas | 1982 |
Mecillinam alone and in combination with ampicillin or moxalactam in experimental Escherichia coli meningitis.
Topics: Amdinocillin; Ampicillin; Animals; Cephalosporins; Cephamycins; Drug Synergism; Drug Therapy, Combination; Escherichia coli; Escherichia coli Infections; Female; Kinetics; Male; Meningitis; Mice; Moxalactam; Penicillanic Acid; Rabbits | 1982 |
Activity of cefoperazone and two beta-lactamase inhibitors, sulbactam and clavulanic acid, against Bacteroides spp. correlated with beta-lactamase production.
Topics: Anti-Bacterial Agents; Bacteroides; beta-Lactamase Inhibitors; beta-Lactamases; Cefoperazone; Cell Membrane Permeability; Cephalosporins; Clavulanic Acids; Drug Synergism; Edetic Acid; Microbial Sensitivity Tests; Penicillanic Acid; Sulbactam | 1982 |
6-Acetylmethylenepenicillanic acid (Ro 15-1903), a potent beta-lactamase inhibitor. I. Inhibition of chromosomally and R-factor-mediated beta-lactamases.
Topics: Bacteria; beta-Lactamase Inhibitors; Cephalosporins; Chromosomes, Bacterial; Hydrolysis; Penicillanic Acid; Penicillins; R Factors | 1982 |
[Studies on the combined effect of 6/N,N-hexyleneformamidine/-penicillanic acid (Preparation HX) and selected beta-lactam antibiotics on Escherichia coli and Salmonella. II. Studies in vivo].
Topics: Amdinocillin; Animals; Anti-Bacterial Agents; Cefazolin; Cephalosporins; Cephradine; Drug Synergism; Escherichia coli Infections; Mice; Mice, Inbred BALB C; Penicillanic Acid; Salmonella Infections | 1982 |
Pharmacokinetics of sulbactam in humans.
Topics: Adult; Ampicillin; Cefoperazone; Cephalosporins; Drug Combinations; Drug Interactions; Gas Chromatography-Mass Spectrometry; Humans; Kinetics; Male; Penicillanic Acid; Penicillin G; Sulbactam | 1983 |
[Antibiotic activity and synergism of ceftazidime and netilmicin against gram-negative pathogenic bacteria].
Topics: Anti-Bacterial Agents; beta-Lactamase Inhibitors; Cefsulodin; Ceftazidime; Cephalosporins; Clavulanic Acid; Clavulanic Acids; Drug Resistance, Microbial; Drug Synergism; Enterobacteriaceae; Gentamicins; Gram-Negative Bacteria; Netilmicin; Penicillanic Acid; Sulbactam | 1983 |
Continuous 6-APA and 7-ADCA production using Semacylase (immobilized PEN-V acylase).
Topics: Amidohydrolases; Cephalosporins; Enzymes, Immobilized; Kinetics; Penicillanic Acid; Penicillin Amidase; Structure-Activity Relationship | 1983 |
[Cefoperazone, cefsulodin and ceftazidime--3 cephalosporins active against Pseudomonas in comparison with their monobactam analogs].
Topics: beta-Lactamase Inhibitors; Cefoperazone; Cefsulodin; Ceftazidime; Cephalosporins; Chemical Phenomena; Chemistry; Clavulanic Acid; Clavulanic Acids; Drug Resistance, Microbial; Humans; Monobactams; Penicillanic Acid; Pseudomonas aeruginosa; Pseudomonas Infections; Sulbactam | 1983 |
Synergistic activity of cefsulodin combined with cefoxitin and sulbactam against Bacteroides species.
Topics: Bacteroides; beta-Lactamase Inhibitors; Cefoxitin; Cefsulodin; Cephalosporins; Drug Resistance, Microbial; Drug Synergism; Penicillanic Acid; Species Specificity; Sulbactam | 1984 |
Spectrophotometric determination of 6-aminopenicillanic and 7-aminocephalosporanic acids as the Schiff bases with para-dimethylaminobenzaldehyde in the presence of sodium dodecyl sulfate micelles.
Topics: Benzaldehydes; Cephalosporins; Indicators and Reagents; Kinetics; Micelles; Microcomputers; Penicillanic Acid; Schiff Bases; Sensitivity and Specificity; Sodium Dodecyl Sulfate; Spectrophotometry; Time Factors | 1995 |
[In vitro activity of six beta-lactams against 295 strains of enterobacteriaceae and P. aeruginosa isolated from neutropenic patients].
Topics: Cefepime; Cefotaxime; Cefpirome; Ceftazidime; Cephalosporins; Drug Resistance, Microbial; Drug Therapy, Combination; Enterobacteriaceae; Humans; Imipenem; In Vitro Techniques; Neutropenia; Penicillanic Acid; Penicillins; Piperacillin; Pseudomonas aeruginosa; Tazobactam; Thienamycins | 1995 |
beta-Lactamase activity in mycobacteria including Mycobacterium avium and suppression of their growth by a beta-lactamase-stable antibiotic.
Topics: Anti-Bacterial Agents; beta-Lactamase Inhibitors; beta-Lactamases; Cefepime; Cell Division; Cephalosporins; Clavulanic Acid; Clavulanic Acids; Drug Resistance, Microbial; Isoniazid; Microbial Sensitivity Tests; Mycobacterium; Mycobacterium avium; Penicillanic Acid; Streptomycin; Sulbactam; Tazobactam | 1995 |
Interaction of tazobactam with Staphylococcus aureus PC1 beta-lactamase: a molecular modelling and enzyme kinetics study.
Topics: Amino Acid Sequence; beta-Lactamase Inhibitors; beta-Lactamases; Binding Sites; Cephalosporins; Computer Simulation; Models, Molecular; Molecular Sequence Data; Penicillanic Acid; Peptide Fragments; Staphylococcus aureus; Tazobactam | 1994 |
Kinetic interactions of tazobactam with beta-lactamases from all major structural classes.
Topics: Bacterial Proteins; beta-Lactamase Inhibitors; beta-Lactamases; Cephalosporins; Clavulanic Acid; Clavulanic Acids; Hydrolysis; Isoelectric Focusing; Kinetics; Molecular Weight; Penicillanic Acid; Spectrophotometry, Ultraviolet; Tazobactam | 1993 |
Molecular genetics of resistance to both ceftazidime and beta-lactam-beta-lactamase inhibitor combinations in Klebsiella pneumoniae and in vivo response to beta-lactam therapy.
Topics: Abdominal Abscess; Amino Acid Sequence; Ampicillin; Animals; Base Sequence; beta-Lactamase Inhibitors; beta-Lactamases; Ceftazidime; Cephalosporin Resistance; Cephalosporins; DNA, Bacterial; Drug Therapy, Combination; Escherichia coli; Klebsiella Infections; Klebsiella pneumoniae; Molecular Biology; Molecular Sequence Data; Penicillanic Acid; Penicillin Resistance; Piperacillin; Piperacillin, Tazobactam Drug Combination; R Factors; Rats; Sulbactam | 1996 |
[From penicillin to the progress in beta-lactams. Chronicle of a 50th anniversary].
Topics: Anti-Bacterial Agents; Cephalosporins; History, 20th Century; Humans; Penicillanic Acid; Penicillins | 1996 |
Assessment of two penicillins plus beta-lactamase inhibitors versus cefotaxime in treatment of murine Klebsiella pneumoniae infections.
Topics: Animals; Anti-Bacterial Agents; beta-Lactamase Inhibitors; Cefotaxime; Cephalosporins; Clavulanic Acid; Clavulanic Acids; Colony Count, Microbial; Drug Combinations; Drug Therapy, Combination; Female; Klebsiella Infections; Klebsiella pneumoniae; Lung; Mice; Microbial Sensitivity Tests; Penicillanic Acid; Penicillins; Piperacillin; Pneumonia, Bacterial; Tazobactam; Ticarcillin | 1996 |
Antimicrobial susceptibilities of Campylobacter jejuni and Campylobacter coli to 12 beta-lactam agents and combinations with beta-lactamase inhibitors.
Topics: Anti-Bacterial Agents; beta-Lactam Resistance; beta-Lactamase Inhibitors; beta-Lactamases; Campylobacter coli; Campylobacter jejuni; Cephalosporins; Clavulanic Acid; Clavulanic Acids; Enzyme Inhibitors; Microbial Sensitivity Tests; Penicillanic Acid; Penicillins; Sulbactam; Tazobactam | 1996 |
Antibiotic resistance and production of extended-spectrum beta-lactamases amongst Klebsiella spp. from intensive care units in Europe.
Topics: Ampicillin; Anti-Bacterial Agents; beta-Lactam Resistance; beta-Lactamase Inhibitors; beta-Lactamases; Carbapenems; Ceftazidime; Cephalosporins; Clavulanic Acid; Clavulanic Acids; Drug Therapy, Combination; Enzyme Inhibitors; Europe; Humans; Intensive Care Units; Klebsiella; Klebsiella Infections; Microbial Sensitivity Tests; Monobactams; Penicillanic Acid; Piperacillin; Tazobactam | 1996 |
Phenoxymethylpenicillin amidohydrolases from Penicillium chrysogenum.
Topics: Cephalosporins; Chromatography, Gel; Chromatography, High Pressure Liquid; Electrophoresis, Polyacrylamide Gel; Enzyme Inhibitors; Enzyme Stability; Hydrogen-Ion Concentration; Molecular Structure; Molecular Weight; Penicillanic Acid; Penicillin Amidase; Penicillin V; Penicillium chrysogenum; Substrate Specificity; Temperature | 1996 |
Timed killing kinetic studies of the interaction between ciprofloxacin and beta-lactams against gram-negative bacilli.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Aztreonam; Ceftazidime; Cephalosporins; Ciprofloxacin; Clavulanic Acid; Clavulanic Acids; Drug Interactions; Drug Therapy, Combination; Enterobacter cloacae; Enzyme Inhibitors; Kinetics; Klebsiella pneumoniae; Microbial Sensitivity Tests; Monobactams; Penicillanic Acid; Penicillins; Piperacillin; Pseudomonas aeruginosa; Serratia marcescens; Tazobactam; Ticarcillin; Time Factors | 1996 |
The inhibitory mechanisms of glucose and carbon dioxide on the biosyntheses of penicillins and cephalosporins.
Topics: Acremonium; Acylation; Biotechnology; Carbohydrate Metabolism; Carbon Dioxide; Cephalosporins; Glucose; Penicillanic Acid; Penicillin G; Penicillins; Penicillium chrysogenum | 1996 |
Efficacies of piperacillin-tazobactam and cefepime in rats with experimental intra-abdominal abscesses due to an extended-spectrum beta-lactamase-producing strain of Klebsiella pneumoniae.
Topics: Abdominal Abscess; Animals; beta-Lactamases; Cefepime; Cephalosporins; Drug Therapy, Combination; Enzyme Inhibitors; Klebsiella Infections; Klebsiella pneumoniae; Male; Microbial Sensitivity Tests; Penicillanic Acid; Piperacillin; Rats; Rats, Sprague-Dawley; Tazobactam | 1997 |
Tazobactam-piperacillin compared with sulbactam-ampicillin, clavulanic acid-ticarcillin, sulbactam-cefoperazone, and piperacillin for activity against beta-lactamase-producing bacteria isolated from patients with complicated urinary tract infections.
Topics: Ampicillin; beta-Lactamase Inhibitors; Cefoperazone; Cephalosporins; Clavulanic Acid; Clavulanic Acids; Colony Count, Microbial; Dose-Response Relationship, Drug; Drug Therapy, Combination; Enzyme Inhibitors; Gram-Negative Bacteria; Gram-Negative Bacterial Infections; Humans; Microbial Sensitivity Tests; Penicillanic Acid; Penicillins; Piperacillin; Retrospective Studies; Sulbactam; Tazobactam; Ticarcillin; Urinary Tract; Urinary Tract Infections | 1997 |
Comparative in vitro evaluation of piperacillin/tazobactam in a tertiary care hospital.
Topics: Amoxicillin; Ceftazidime; Cephalosporin Resistance; Cephalosporins; Ciprofloxacin; Clavulanic Acid; Enzyme Inhibitors; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; Intensive Care Units; Microbial Sensitivity Tests; Penicillanic Acid; Penicillin Resistance; Penicillins; Piperacillin; Tazobactam | 1997 |
Phenotypic study of resistance of beta-lactamase-inhibitor-resistant TEM enzymes which differ by naturally occurring variations and by site-directed substitution at Asp276.
Topics: Amoxicillin; beta-Lactamase Inhibitors; beta-Lactamases; Cephalosporins; Enzyme Inhibitors; Escherichia coli; Models, Molecular; Mutagenesis, Site-Directed; Penicillanic Acid; Penicillins; Phenotype; Tazobactam | 1998 |
Ceftazidime and aztreonam resistance in Providencia stuartii: characterization of a natural TEM-derived extended-spectrum beta-lactamase, TEM-60.
Topics: Anti-Bacterial Agents; Aztreonam; beta-Lactamase Inhibitors; beta-Lactamases; Ceftazidime; Cephalosporins; Clavulanic Acid; Drug Interactions; Drug Resistance, Multiple; Enzyme Inhibitors; Isoelectric Focusing; Microbial Sensitivity Tests; Molecular Sequence Data; Monobactams; Penicillanic Acid; Providencia; Sulbactam; Tazobactam | 1998 |
Synthesis and evaluation of 2 beta-oxyimino and alkenylpenicillanic acid sulfone derivatives as beta-lactamase inhibitors.
Topics: beta-Lactamase Inhibitors; Ceftriaxone; Cephalosporins; Citrobacter freundii; Drug Synergism; Enzyme Inhibitors; Microbial Sensitivity Tests; Penicillanic Acid; Penicillins; Piperacillin; Sulfones | 1999 |
Efficacy of beta-lactam and inhibitor combinations in a diffusion chamber model in rabbits.
Topics: Animals; Ceftriaxone; Cephalosporin Resistance; Cephalosporins; Colony Count, Microbial; Diffusion Chambers, Culture; Drug Therapy, Combination; Enterobacter; Enterobacteriaceae; Enterobacteriaceae Infections; Enzyme Inhibitors; Escherichia coli; Humans; Klebsiella pneumoniae; Microbial Sensitivity Tests; Penicillanic Acid; Rabbits; Tazobactam | 1999 |
In vitro and in vivo activities of Syn2190, a novel beta-lactamase inhibitor.
Topics: Animals; beta-Lactamase Inhibitors; beta-Lactamases; Cefpirome; Ceftazidime; Cephalosporins; Citrobacter freundii; Drug Synergism; Enterobacter cloacae; Enterobacteriaceae; Enzyme Induction; Enzyme Inhibitors; Female; Male; Mice; Microbial Sensitivity Tests; Monobactams; Penicillanic Acid; Pseudomonas aeruginosa; Tazobactam | 1999 |
Treatment of experimental pneumonia in rats caused by a PER-1 extended-spectrum beta-lactamase-producing strain of Pseudomonas aeruginosa.
Topics: Amikacin; Animals; Anti-Bacterial Agents; beta-Lactamases; Cefepime; Cephalosporins; Colony Count, Microbial; Disease Models, Animal; Drug Synergism; Drug Therapy, Combination; Imipenem; Lung; Male; Microbial Sensitivity Tests; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Pneumonia, Bacterial; Pseudomonas aeruginosa; Pseudomonas Infections; Rats; Rats, Wistar | 1999 |
In vitro activity of newer broad spectrum beta-lactam antibiotics against enterobacteriaceae and non-fermenters: a report from Austrian intensive care units. Austrian Carbapenem Susceptibility Surveillance Group.
Topics: Acinetobacter; Anti-Bacterial Agents; Austria; beta-Lactam Resistance; Carbapenems; Cephalosporins; Enterobacteriaceae; Humans; Imipenem; In Vitro Techniques; Intensive Care Units; Meropenem; Microbial Sensitivity Tests; Penicillanic Acid; Pseudomonadaceae; Tazobactam; Thienamycins | 1999 |
Comparison of five beta-lactam antibiotics against common nosocomial pathogens using the time above MIC at different creatinine clearances.
Topics: Anti-Bacterial Agents; Bacteria; Cefepime; Ceftazidime; Cephalosporins; Creatinine; Humans; Imipenem; In Vitro Techniques; Microbial Sensitivity Tests; Models, Biological; Penicillanic Acid; Piperacillin; Tazobactam; Time Factors | 1999 |
High-level expression of chromosomally encoded SHV-1 beta-lactamase and an outer membrane protein change confer resistance to ceftazidime and piperacillin-tazobactam in a clinical isolate of Klebsiella pneumoniae.
Topics: Bacterial Outer Membrane Proteins; Base Sequence; beta-Lactamases; Biological Transport; Ceftazidime; Cephalosporins; Chromosomes; Cloning, Molecular; DNA, Bacterial; Drug Resistance, Microbial; Enzyme Inhibitors; Gene Expression Regulation, Bacterial; Humans; Klebsiella pneumoniae; Microbial Sensitivity Tests; Molecular Sequence Data; Nucleic Acid Hybridization; Penicillanic Acid; Penicillins; Piperacillin; Promoter Regions, Genetic; Sequence Homology, Nucleic Acid; Tazobactam | 2000 |
Synthesis and antibacterial activity of new arylamido derivatives of 6 beta-aminopenicillanic, 7 beta-aminocephalosporanic and 7 beta-aminodesacetoxycephalosporanic acids.
Topics: Bacillus; Bacteria; Cephalosporins; Chemical Phenomena; Chemistry, Physical; Culture Media; Escherichia coli; Microbial Sensitivity Tests; Penicillanic Acid; Penicillins; Staphylococcus aureus | 2000 |
Control of glycopeptide-resistant enterococci in an oncology unit.
Topics: Anti-Bacterial Agents; Ceftazidime; Cephalosporins; Cohort Studies; Cross Infection; Drug Resistance, Microbial; Drug Therapy, Combination; Enzyme Inhibitors; Fever; Glycopeptides; Humans; Infection Control; Neoplasms; Neutropenia; Oncology Service, Hospital; Penicillanic Acid; Penicillins; Piperacillin; Prospective Studies; Tazobactam; Treatment Outcome | 2000 |
Reduction of vancomycin-resistant enterococcal infections by limitation of broad-spectrum cephalosporin use in a trauma and burn intensive care unit.
Topics: Burn Units; Cephalosporins; Clinical Protocols; Cross Infection; Drug Utilization; Enterococcus; Gram-Positive Bacterial Infections; Humans; Intensive Care Units; Methicillin Resistance; Microbial Sensitivity Tests; Penicillanic Acid; Piperacillin; Staphylococcal Infections; Staphylococcus aureus; Tazobactam; Vancomycin; Vancomycin Resistance; Wounds and Injuries | 2000 |
Properties of multidrug-resistant, ESBL-producing Proteus mirabilis isolates and possible role of beta-lactam/beta-lactamase inhibitor combinations.
Topics: Anti-Bacterial Agents; beta-Lactamase Inhibitors; beta-Lactamases; Cephalosporins; Clavulanic Acid; Drug Resistance, Microbial; Drug Resistance, Multiple; Enzyme Inhibitors; Genes, Bacterial; Humans; Microbial Sensitivity Tests; Penicillanic Acid; Proteus Infections; Proteus mirabilis; Tazobactam | 2001 |
Thermophilic multidrug-resistant Campylobacter fetus infection with hypersplenism and histiocytic phagocytosis in a patient with acquired immunodeficiency syndrome.
Topics: Acquired Immunodeficiency Syndrome; Adult; Anti-Bacterial Agents; Campylobacter fetus; Campylobacter Infections; Ceftazidime; Cephalosporins; Diarrhea; Drug Resistance, Microbial; Enzyme Inhibitors; Erythromycin; Histiocytes; Histiocytosis; Humans; Hypersplenism; Male; Penicillanic Acid; Penicillins; Phagocytosis; Piperacillin; Quinolones; Splenic Infarction; Splenomegaly; Tazobactam | 2001 |
Cefepime, piperacillin-tazobactam, and the inoculum effect in tests with extended-spectrum beta-lactamase-producing Enterobacteriaceae.
Topics: Anti-Bacterial Agents; Bacterial Proteins; beta-Lactamase Inhibitors; beta-Lactamases; Cefepime; Cephalosporins; Chromosomes, Bacterial; Drug Resistance, Microbial; Enterobacteriaceae; Enzyme Inhibitors; Escherichia coli; Microbial Sensitivity Tests; Penicillanic Acid; Penicillins; Piperacillin; Tazobactam | 2001 |
Physiological characterisation of Penicillium chrysogenum strains expressing the expandase gene from Streptomyces clavuligerus during batch cultivations. Growth and adipoyl-7-aminodeacetoxycephalosporanic acid production.
Topics: Adipates; Cephalosporins; Fructose; Gluconates; Glucose; Intramolecular Transferases; Mutagenesis, Insertional; Penicillanic Acid; Penicillin-Binding Proteins; Penicillium chrysogenum; Streptomyces; Sucrose | 2001 |
Synthesis and antibacterial activity of 5-nitrofuryl and 3-methoxy-2-nitrophenyl derivatives of 6 beta-aminopenicillanic, 7 beta-aminocephalosporanic and 7 beta-aminodesacetoxy-cephalosporanic acids.
Topics: Bacteria; Cephalosporins; Chemical Phenomena; Chemistry, Physical; Culture Media; Indicators and Reagents; Magnetic Resonance Spectroscopy; Microbial Sensitivity Tests; Penicillanic Acid; Penicillins; Spectrophotometry, Infrared; Structure-Activity Relationship | 2001 |
Emerging antimicrobial resistances among Proteus mirabilis in Europe: report from the MYSTIC Program (1997-2001). Meropenem Yearly Susceptibility Test Information Collection.
Topics: Anti-Bacterial Agents; Cefepime; Ceftazidime; Cephalosporins; Ciprofloxacin; Critical Care; Cystic Fibrosis; Data Collection; Drug Resistance, Bacterial; Europe; Humans; Imipenem; Meropenem; Microbial Sensitivity Tests; Neutropenia; Penicillanic Acid; Piperacillin; Population Surveillance; Proteus Infections; Proteus mirabilis; Tazobactam; Thienamycins | 2002 |
Cefepime, piperacillin/tazobactam, gentamicin, ciprofloxacin, and levofloxacin alone and in combination against Pseudomonas aeruginosa.
Topics: Cefepime; Cephalosporins; Ciprofloxacin; Drug Resistance, Microbial; Drug Therapy, Combination; Gentamicins; Humans; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Penicillanic Acid; Piperacillin; Pseudomonas aeruginosa; Sensitivity and Specificity; Tazobactam | 2002 |
Quantitative characterization of the nucleophile reactivity in penicillin acylase-catalyzed acyl transfer reactions.
Topics: Catalysis; Cephalosporins; Penicillanic Acid; Penicillin Amidase; Substrate Specificity | 2002 |
The effect of an enhanced infection-control policy on the incidence of Clostridium difficile infection and methicillin-resistant Staphyloccocus aureus colonization in acute elderly medical patients.
Topics: Aged; Cephalosporins; Clostridioides difficile; Communicable Disease Control; Cross Infection; Cross-Sectional Studies; Drug Utilization; England; Enterocolitis, Necrotizing; Hand Disinfection; Humans; Methicillin Resistance; Penicillanic Acid; Staphylococcal Infections; Staphylococcus aureus; Trimethoprim | 1998 |
Pharmacokinetics-pharmacodynamics of cefepime and piperacillin-tazobactam against Escherichia coli and Klebsiella pneumoniae strains producing extended-spectrum beta-lactamases: report from the ARREST program.
Topics: beta-Lactamases; Cefepime; Cephalosporins; Drug Therapy, Combination; Escherichia coli; Humans; Klebsiella pneumoniae; Microbial Sensitivity Tests; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Probability | 2003 |
In vitro activity of piperacillin/tazobactam and other broad-spectrum antibiotics against bacteria from hospitalised patients in the British Isles.
Topics: Bacteria; Bacterial Infections; Cephalosporins; Drug Resistance, Bacterial; Drug Therapy, Combination; Enterobacteriaceae; Gram-Negative Bacteria; Humans; In Vitro Techniques; Ireland; Microbial Sensitivity Tests; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Time Factors; United Kingdom | 2003 |
Kinetics of enzyme acylation and deacylation in the penicillin acylase-catalyzed synthesis of beta-lactam antibiotics.
Topics: Acylation; Anti-Bacterial Agents; Binding Sites; Binding, Competitive; Catalysis; Cephalosporins; Deuterium; Escherichia coli; Glycine; Hydrolysis; Kinetics; Penicillanic Acid; Penicillin Amidase; Phenylacetates; Protons; Spectrophotometry, Ultraviolet; Substrate Specificity | 2003 |
[Pharmacokinetics of antibiotics in inflamed and healthy lung tissue].
Topics: Anti-Bacterial Agents; Cefpirome; Cephalosporins; Empyema, Pleural; Extracellular Space; Humans; Lung; Microbial Sensitivity Tests; Microdialysis; Penicillanic Acid; Piperacillin; Pneumonia, Bacterial; Tazobactam; Thoracotomy | 2003 |
Distribution and substrate specificity of benzylpenicillin acylase.
Topics: Cephalosporins; Esterases; Nocardia; Penicillanic Acid; Penicillin Amidase; Penicillin G; Penicillins; Proteus; Substrate Specificity | 1963 |
6-AMINOPENICILLANIC ACID: INHIBITION OF DESTRUCTION OF CEPHALOSPORIN C BY BACTERIA.
Topics: Acremonium; Aeromonas; Alcaligenes; Anti-Bacterial Agents; Bacillus subtilis; Bacteria; Cephalosporins; Enterobacter aerogenes; Enzyme Inhibitors; Erwinia; Escherichia coli; Lactobacillus; Penicillanic Acid; Penicillins; Propionibacterium; Proteins; Proteus; Pseudomonas; Pseudomonas aeruginosa; Research; Serratia marcescens; Staphylococcus; Vibrio | 1964 |
ANTIBACTERIAL ACTIVITY OF SOME DERIVATIVES OF 7-AMINOCEPHALOSPORANIC ACID AGAINST STAPHYLOCOCCUS AUREUS AND SYNERGISM BETWEEN THESE AND OTHER ANTIBIOTICS.
Topics: Animals; Anti-Bacterial Agents; Antibiotics, Antitubercular; Cephalosporins; Coagulase; Drug Resistance; Drug Resistance, Microbial; Fusidic Acid; Methicillin; Mice; Penicillanic Acid; Penicillin G; Penicillinase; Pharmacology; Research; Staphylococcal Infections; Staphylococcus; Staphylococcus aureus | 1964 |
METABOLIC CONTROL OF PENICILLINASE BIOSYNTHESIS IN BACILLUS CEREUS.
Topics: Azaguanine; Bacillus cereus; Cephalosporins; Cytosine; Dactinomycin; Enzyme Inhibitors; Mercury; Penicillanic Acid; Penicillin G; Penicillinase; Penicillins; Pharmacology; Proteins; Research; RNA; RNA, Messenger; Thymine; Uracil | 1964 |
In vitro activity of combination therapy with cefepime, piperacillin-tazobactam, or meropenem with ciprofloxacin against multidrug-resistant Pseudomonas aeruginosa strains.
Topics: Anti-Bacterial Agents; Cefepime; Cephalosporins; Drug Interactions; Drug Resistance, Multiple; Drug Therapy, Combination; Humans; Lactams; Meropenem; Microbial Sensitivity Tests; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Pseudomonas aeruginosa; Pseudomonas Infections; Thienamycins | 2003 |
Replacement of broad-spectrum cephalosporins by piperacillin-tazobactam: impact on sustained high rates of bacterial resistance.
Topics: Anti-Bacterial Agents; Argentina; Cephalosporin Resistance; Cephalosporins; Cross Infection; Drug Prescriptions; Drug Utilization; Humans; Infection Control; Klebsiella Infections; Klebsiella pneumoniae; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination | 2004 |
Penicillin acylase-catalyzed synthesis of beta-lactam antibiotics in highly condensed aqueous systems: beneficial impact of kinetic substrate supersaturation.
Topics: Amoxicillin; Ampicillin; Anti-Bacterial Agents; beta-Lactams; Catalysis; Cephalexin; Cephalosporins; Enzyme Activation; Escherichia coli; Kinetics; Penicillanic Acid; Penicillin Amidase; Solutions; Substrate Specificity; Water | 2004 |
Synergistic activities of moxifloxacin combined with piperacillin-tazobactam or cefepime against Klebsiella pneumoniae, Enterobacter cloacae, and Acinetobacter baumannii clinical isolates.
Topics: Acinetobacter baumannii; Acinetobacter Infections; Anti-Infective Agents; Aza Compounds; Cefepime; Cephalosporins; Colony Count, Microbial; Drug Synergism; Enterobacter cloacae; Enterobacteriaceae Infections; Enzyme Inhibitors; Fluoroquinolones; Humans; Klebsiella Infections; Klebsiella pneumoniae; Moxifloxacin; Penicillanic Acid; Penicillins; Piperacillin; Quinolines; Tazobactam | 2004 |
In vitro antimicrobial activity of doripenem, a new carbapenem.
Topics: Anti-Bacterial Agents; Bacteria; Carbapenems; Cephalosporins; Doripenem; Drug Therapy, Combination; Enterobacteriaceae; Gram-Positive Bacteria; Microbial Sensitivity Tests; Penicillanic Acid; Penicillin Resistance; Penicillins; Piperacillin; Tazobactam | 2004 |
Comparative study of the effects of ceftizoxime, piperacillin, and piperacillin-tazobactam concentrations on antibacterial activity and selection of antibiotic-resistant mutants of Enterobacter cloacae and Bacteroides fragilis in vitro and in vivo in mixe
Topics: Abscess; Animals; Bacteroides fragilis; Ceftizoxime; Cephalosporins; Colony Count, Microbial; Drug Resistance; Enterobacter cloacae; Enzyme Inhibitors; Female; Mice; Mice, Inbred BALB C; Mutation; Penicillanic Acid; Penicillins; Piperacillin; Tazobactam | 2004 |
Exploring the effectiveness of tazobactam against ceftazidime resistant Escherichia coli: insights from the comparison between susceptibility testing and beta-lactamase inhibition.
Topics: Anti-Bacterial Agents; Bacterial Proteins; beta-Lactamase Inhibitors; beta-Lactamases; beta-Lactams; Cefepime; Ceftazidime; Cephalosporins; Drug Resistance, Bacterial; Drug Therapy, Combination; Enzyme Inhibitors; Ertapenem; Escherichia coli; Escherichia coli Infections; Lactams; Microbial Sensitivity Tests; Penicillanic Acid; Tazobactam | 2004 |
In vitro killing of parenteral beta-lactams against standard and high inocula of extended-spectrum beta-lactamase and non-ESBL producing Klebsiella pneumoniae.
Topics: Anti-Bacterial Agents; beta-Lactamases; beta-Lactams; Cefepime; Cephalosporins; Culture Media, Conditioned; Drug Resistance, Bacterial; Humans; In Vitro Techniques; Klebsiella pneumoniae; Meropenem; Microbial Sensitivity Tests; Penicillanic Acid; Piperacillin; Sensitivity and Specificity; Tazobactam; Thienamycins | 2004 |
Long-term surveillance of cefotaxime and piperacillin-tazobactam prescribing and incidence of Clostridium difficile diarrhoea.
Topics: Aged; Anti-Bacterial Agents; Cefotaxime; Cephalosporins; Clostridioides difficile; Diarrhea; Drug Prescriptions; Drug Resistance; Drug Utilization; Humans; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Public Policy; Retrospective Studies; United Kingdom | 2004 |
In vitro activity of AVE1330A, an innovative broad-spectrum non-beta-lactam beta-lactamase inhibitor.
Topics: Azepines; Bacteria; beta-Lactamases; Ceftazidime; Cephalosporins; Clavulanic Acid; Dealkylation; Enzyme Inhibitors; Escherichia coli; Microbial Sensitivity Tests; Penicillanic Acid; Penicillins; Piperacillin; Staphylococcus aureus; Sulfuric Acid Esters; Tazobactam | 2004 |
[Treatment mostly not in line with current knowledge. New guidelines for sinusitis therapy].
Topics: Acute Disease; Bacterial Infections; Ceftibuten; Cephalosporins; Chronic Disease; Clavulanic Acid; Drug Resistance, Multiple; Humans; Mometasone Furoate; Penicillanic Acid; Pregnadienediols; Sinusitis; Treatment Outcome | 2004 |
Continuous infusion beta-lactams for intensive care unit pulmonary infections.
Topics: Anti-Bacterial Agents; Aztreonam; beta-Lactams; Cefepime; Ceftazidime; Cephalosporins; Computer Simulation; Drug Combinations; Gram-Negative Bacteria; Gram-Negative Bacterial Infections; Humans; Infusions, Intravenous; Intensive Care Units; Microbial Sensitivity Tests; Monte Carlo Method; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Pneumonia, Bacterial; United States | 2005 |
Pharmacodynamics of intermittent and continuous infusion piperacillin/tazobactam and cefepime against extended-spectrum beta-lactamase-producing organisms.
Topics: beta-Lactam Resistance; beta-Lactamases; Cefepime; Cephalosporins; Drug Therapy, Combination; Escherichia coli; Infusion Pumps; Klebsiella pneumoniae; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination | 2005 |
In vitro activity of ceftriaxone plus tazobactam against members of Enterobacteriaceae.
Topics: Anti-Bacterial Agents; beta-Lactamase Inhibitors; Ceftriaxone; Cephalosporins; Drug Therapy, Combination; Enterobacteriaceae; Enzyme Inhibitors; Hospital Units; In Vitro Techniques; Microbial Sensitivity Tests; Penicillanic Acid; Tazobactam | 2005 |
Pharmacodynamics of antimicrobials for the empirical treatment of nosocomial pneumonia: a report from the OPTAMA Program.
Topics: Anti-Bacterial Agents; Cefepime; Ceftazidime; Cephalosporins; Ciprofloxacin; Cross Infection; Dose-Response Relationship, Drug; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; Imipenem; Meropenem; Microbial Sensitivity Tests; Monte Carlo Method; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Pneumonia, Bacterial; Thienamycins | 2005 |
Cefepime- and cefixime-induced encephalopathy in a patient with normal renal function.
Topics: Aged, 80 and over; Anti-Bacterial Agents; Brain; Cefepime; Cefixime; Cephalosporins; Confusion; Consciousness Disorders; Delirium; Epididymitis; Humans; Kidney; Male; Metabolic Clearance Rate; Neurotoxicity Syndromes; Penicillanic Acid; Piperacillin; Recovery of Function; Secondary Prevention; Systemic Inflammatory Response Syndrome; Tazobactam; Urinary Tract Infections; Withholding Treatment | 2005 |
[The combination effects of antibacterial agents against clinical isolated multiple-drug resistant Pseudomonas aeruginosa].
Topics: Amikacin; Anti-Bacterial Agents; Aztreonam; Cefepime; Cefoperazone; Cephalosporins; Ciprofloxacin; Drug Combinations; Drug Resistance, Multiple, Bacterial; Drug Therapy, Combination; Fluoroquinolones; Humans; Meropenem; Microbial Sensitivity Tests; Oxazines; Penicillanic Acid; Piperacillin; Pseudomonas aeruginosa; Sulbactam; Tazobactam; Thienamycins | 2006 |
Prospective drug utilization evaluation of three broad-spectrum antimicrobials: cefepime, piperacillin-tazobactam and meropenem.
Topics: Anti-Bacterial Agents; Cefepime; Cephalosporins; Drug Utilization Review; Humans; Meropenem; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Thienamycins | 2006 |
Risk factors for isolation of low-level mupirocin-resistant versus -susceptible methicillin-resistant Staphylococcus aureus from patients in intensive care units.
Topics: Adult; Aged; Anti-Bacterial Agents; Case-Control Studies; Cephalosporins; Drug Resistance, Bacterial; Female; Humans; Intensive Care Units; Male; Methicillin Resistance; Microbial Sensitivity Tests; Middle Aged; Mupirocin; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Quinolones; Risk Factors; Staphylococcal Infections; Staphylococcus aureus | 2007 |
Antibiotic-induced enterococcal expansion in the mouse intestine occurs throughout the small bowel and correlates poorly with suppression of competing flora.
Topics: Animals; Anti-Bacterial Agents; Cephalosporins; Clavulanic Acids; Clindamycin; Drug Resistance, Multiple, Bacterial; Enterococcus faecium; Escherichia coli; Green Fluorescent Proteins; Intestine, Small; Metronidazole; Mice; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Ticarcillin | 2006 |
Evaluating broad-spectrum antimicrobials.
Topics: Animals; Anti-Bacterial Agents; Cefepime; Cephalosporins; Humans; Meropenem; Microbial Sensitivity Tests; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Thienamycins | 2006 |
Bacteremia due to extended-spectrum beta -lactamase-producing Escherichia coli in the CTX-M era: a new clinical challenge.
Topics: Adult; Aged; Aged, 80 and over; Amoxicillin-Potassium Clavulanate Combination; Anti-Bacterial Agents; Bacteremia; beta-Lactamases; Cephalosporins; Cohort Studies; Community-Acquired Infections; Cross Infection; Drug Resistance, Multiple, Bacterial; Escherichia coli; Escherichia coli Infections; Female; Fluoroquinolones; Humans; Male; Middle Aged; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination | 2006 |
Comparative activities of cefepime and piperacillin/tazobactam tested against a global collection of Escherichia coli and Klebsiella spp. with an ESBL phenotype.
Topics: Anti-Bacterial Agents; beta-Lactamases; Cefepime; Cephalosporins; Drug Resistance, Multiple, Bacterial; Escherichia coli; Humans; Klebsiella; Microbial Sensitivity Tests; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination | 2007 |
Differences in the changes in resistance patterns to third- and fourth-generation cephalosporins and piperacillin/tazobactam among Klebsiella pneumoniae and Escherichia coli clinical isolates following a restriction policy in a Greek tertiary care hospita
Topics: Anti-Bacterial Agents; beta-Lactamase Inhibitors; beta-Lactamases; Cephalosporin Resistance; Cephalosporins; Cross Infection; Drug Resistance, Bacterial; Drug Utilization; Enterobacteriaceae Infections; Enzyme Inhibitors; Escherichia coli; Greece; Humans; Klebsiella pneumoniae; Microbial Sensitivity Tests; Penicillanic Acid; Penicillin Resistance; Piperacillin; Prospective Studies; Tazobactam; Time Factors | 2007 |
Epidemiology of bacteremia and factors associated with multi-drug-resistant gram-negative bacteremia in hematopoietic stem cell transplant recipients.
Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; Bacteremia; Brazil; Carbapenems; Cephalosporins; Child; Child, Preschool; Drug Resistance, Multiple; Female; Gram-Negative Bacterial Infections; Hematopoietic Stem Cell Transplantation; Humans; Incidence; Infant; Male; Middle Aged; Neutropenia; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Predictive Value of Tests; Prospective Studies; Risk Factors | 2007 |
Piperacillin/tazobactam-induced seizure rapidly reversed by high flux hemodialysis in a patient on peritoneal dialysis.
Topics: Anti-Bacterial Agents; Brain; Bronchiectasis; Cefazolin; Cefepime; Cephalosporins; Electroencephalography; Epilepsies, Myoclonic; Female; Humans; Magnetic Resonance Imaging; Middle Aged; Molecular Structure; Penicillanic Acid; Penicillin G; Peritoneal Dialysis, Continuous Ambulatory; Piperacillin; Piperacillin, Tazobactam Drug Combination; Renal Dialysis; Tomography, X-Ray Computed | 2007 |
Use of cefepime for the treatment of infections caused by extended spectrum: beta-lactamase-producing Klebsiella pneumoniae and Escherichia coli.
Topics: Anti-Bacterial Agents; beta-Lactamases; Cefepime; Cephalosporins; Drug Resistance, Multiple, Bacterial; Escherichia coli; Escherichia coli Infections; Hospitals, Urban; Humans; India; Intensive Care Units; Klebsiella Infections; Klebsiella pneumoniae; Meropenem; Microbial Sensitivity Tests; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Sepsis; Thienamycins | 2007 |
Site-specific protonation microequilibria of penicillin and cephalosporin beta-lactam core molecules.
Topics: beta-Lactams; Cephalosporins; Hydrogen-Ion Concentration; Ions; Magnetic Resonance Spectroscopy; Osmolar Concentration; Penicillanic Acid; Penicillins; Potentiometry; Protons | 2007 |
Cefepime restriction improves gram-negative overall resistance patterns in neonatal intensive care unit.
Topics: Anti-Bacterial Agents; Cefepime; Cephalosporins; Cohort Studies; Drug Resistance, Multiple, Bacterial; Gram-Negative Bacterial Infections; Humans; Infant, Newborn; Infant, Premature; Intensive Care Units, Neonatal; Meropenem; Microbial Sensitivity Tests; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Prospective Studies; Thienamycins; Time Factors | 2007 |
Control of multi-resistant bacteria and ventilator-associated pneumonia: is it possible with changes in antibiotics?
Topics: Anti-Bacterial Agents; Cephalosporins; Cross Infection; Drug Resistance, Multiple, Bacterial; Female; Gram-Negative Bacteria; Hospitals, University; Humans; Intensive Care Units; Male; Microbial Sensitivity Tests; Middle Aged; Penicillanic Acid; Piperacillin; Pneumonia, Ventilator-Associated; Prospective Studies; Tazobactam | 2007 |
Biochemical Characterization of SFC-1, a class A carbapenem-hydrolyzing beta-lactamase.
Topics: Aztreonam; beta-Lactamases; Carbapenems; Catalysis; Cephalosporins; Clavulanic Acid; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Hydrolysis; Kinetics; Molecular Weight; Penicillanic Acid; Penicillins; Recombinant Proteins; Serratia; Sulbactam; Tazobactam | 2007 |
Impact of antibiotic restriction on broad spectrum antibiotic usage in the ICU of a developing country.
Topics: Anti-Bacterial Agents; Cefepime; Cephalosporins; Developing Countries; Drug Prescriptions; Drug Resistance, Microbial; Drug Utilization Review; Humans; Imipenem; Intensive Care Units; Medical Order Entry Systems; Organizational Policy; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Polymyxin B; Program Development; Vancomycin | 2007 |
Acquisition of rectal colonization by vancomycin-resistant Enterococcus among intensive care unit patients treated with piperacillin-tazobactam versus those receiving cefepime-containing antibiotic regimens.
Topics: Aged; Anti-Bacterial Agents; Cefepime; Cephalosporins; Culture Media; Enterococcus; Female; Gram-Positive Bacterial Infections; Humans; Intensive Care Units; Male; Microbial Sensitivity Tests; Middle Aged; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Rectum; Vancomycin Resistance | 2008 |
[Replacement of third-generation cephalosporins by piperacillin-tazobactam decreases colonization of extended-spectrum beta-lactamases-producing intestinal Escherichia coli].
Topics: Adult; Aged; Anti-Bacterial Agents; beta-Lactam Resistance; beta-Lactamases; Cephalosporins; Escherichia coli; Escherichia coli Infections; Female; Humans; Intestines; Male; Middle Aged; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Prospective Studies | 2007 |
Occurrence of ESBL & Amp-C beta-lactamases & susceptibility to newer antimicrobial agents in complicated UTI.
Topics: Anti-Bacterial Agents; Aztreonam; Bacterial Proteins; beta-Lactamases; Cefepime; Cephalosporins; Drug Resistance, Bacterial; Humans; Penicillanic Acid; Piperacillin; Prospective Studies; Tazobactam; Urinary Tract Infections | 2008 |
Cephalosporin induced toxic epidermal necrolysis and subsequent penicillin drug exanthem.
Topics: Aged, 80 and over; Cephalosporins; Drug Hypersensitivity; Exanthema; Humans; Male; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Stevens-Johnson Syndrome | 2008 |
Evaluation of sensitivity of different organisms to cefepime and tazobactum (megapime XP) in comparison to cefepime and ceftazidime.
Topics: Anti-Bacterial Agents; Bacteria; Cefepime; Ceftazidime; Cephalosporins; Drug Combinations; Gram-Negative Bacteria; Gram-Positive Bacteria; Penicillanic Acid; Tazobactam | 2008 |
Detection of the novel extended-spectrum beta-lactamase OXA-161 from a plasmid-located integron in Pseudomonas aeruginosa clinical isolates from Spain.
Topics: Amikacin; Aminoglycosides; Anti-Bacterial Agents; beta-Lactamases; Cefepime; Cephalosporins; Clavulanic Acid; Gentamicins; Humans; Imipenem; Integrons; Meropenem; Molecular Sequence Data; Penicillanic Acid; Piperacillin; Plasmids; Pseudomonas aeruginosa; Pseudomonas Infections; Spain; Tazobactam; Thienamycins | 2009 |
In vitro potency of CXA-101, a novel cephalosporin, against Pseudomonas aeruginosa displaying various resistance phenotypes, including multidrug resistance.
Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; Cephalosporins; Child; Child, Preschool; Cross Infection; Drug Combinations; Drug Resistance, Multiple, Bacterial; Humans; Infant; Microbial Sensitivity Tests; Middle Aged; Penicillanic Acid; Pseudomonas aeruginosa; Tazobactam; Young Adult | 2010 |
Empiric combination antibiotic therapy is associated with improved outcome against sepsis due to Gram-negative bacteria: a retrospective analysis.
Topics: Acinetobacter Infections; Adult; Aged; Aminoglycosides; Anti-Bacterial Agents; Carbapenems; Cefepime; Cephalosporins; Cohort Studies; Drug Therapy, Combination; Escherichia coli Infections; Female; Fluoroquinolones; Gram-Negative Bacterial Infections; Hospital Mortality; Humans; Logistic Models; Male; Middle Aged; Multivariate Analysis; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Pseudomonas aeruginosa; Pseudomonas Infections; Retrospective Studies; Sepsis; Shock, Septic | 2010 |
Insufficient β-lactam concentrations in the early phase of severe sepsis and septic shock.
Topics: Anti-Bacterial Agents; beta-Lactams; Cefepime; Ceftazidime; Cephalosporins; Chromatography, High Pressure Liquid; Drug Therapy, Combination; Female; Humans; Male; Meropenem; Microbial Sensitivity Tests; Middle Aged; Penicillanic Acid; Piperacillin; Prospective Studies; Sepsis; Shock, Septic; Tazobactam; Thienamycins | 2010 |
Chequerboard titration of cephalosporin CXA-101 (FR264205) and tazobactam versus beta-lactamase-producing Enterobacteriaceae.
Topics: Anti-Bacterial Agents; Bacterial Proteins; beta-Lactamase Inhibitors; beta-Lactamases; Cephalosporins; Enterobacteriaceae; Enzyme Inhibitors; Microbial Sensitivity Tests; Penicillanic Acid; Tazobactam | 2010 |
Activity of ACHN-490 tested alone and in combination with other agents against Pseudomonas aeruginosa.
Topics: Anti-Bacterial Agents; Carbapenems; Cefepime; Cephalosporins; Doripenem; Imipenem; Microbial Sensitivity Tests; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Pseudomonas aeruginosa | 2011 |
Antimicrobial activity of CXA-101, a novel cephalosporin tested in combination with tazobactam against Enterobacteriaceae, Pseudomonas aeruginosa, and Bacteroides fragilis strains having various resistance phenotypes.
Topics: Bacteroides fragilis; Cephalosporins; Drug Resistance, Bacterial; Enterobacteriaceae; Microbial Sensitivity Tests; Penicillanic Acid; Pseudomonas aeruginosa; Tazobactam | 2011 |
AmpG inactivation restores susceptibility of pan-beta-lactam-resistant Pseudomonas aeruginosa clinical strains.
Topics: Aztreonam; Bacterial Proteins; beta-Lactams; Cefepime; Ceftazidime; Cephalosporins; Drug Resistance, Bacterial; Membrane Transport Proteins; Meropenem; Microbial Sensitivity Tests; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Pseudomonas aeruginosa; Thienamycins | 2011 |
Impact of evaluating antibiotic concentrations in abdominal abscesses percutaneously drained.
Topics: Abdominal Abscess; Aged; Aged, 80 and over; Anti-Bacterial Agents; Cefepime; Cephalosporins; Ciprofloxacin; Exudates and Transudates; Female; Fluconazole; Humans; Male; Metronidazole; Middle Aged; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Prospective Studies; Suction; Treatment Outcome; Vancomycin | 2011 |
Antibiotic resistance in Pseudomonas aeruginosa related to quinolone formulary changes: an interrupted time series analysis.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Cefepime; Cephalosporins; Drug Resistance, Multiple, Bacterial; Fluoroquinolones; Formularies, Hospital as Topic; Humans; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Pseudomonas aeruginosa; Pseudomonas Infections; Tobramycin | 2011 |
In vitro activity of CXA-101 plus tazobactam (CXA-201) against CTX-M-14- and CTX-M-15-producing Escherichia coli and Klebsiella pneumoniae.
Topics: Anti-Bacterial Agents; Bacterial Typing Techniques; beta-Lactamases; Cephalosporins; Escherichia coli; Escherichia coli Infections; Genotype; Humans; Klebsiella Infections; Klebsiella pneumoniae; Microbial Sensitivity Tests; Molecular Typing; Penicillanic Acid; Tazobactam | 2011 |
The impact of a nationwide antibiotic restriction program on antibiotic usage and resistance against nosocomial pathogens in Turkey.
Topics: Acinetobacter; Anti-Bacterial Agents; Cefepime; Ceftazidime; Ceftriaxone; Cephalosporins; Cost Savings; Cross Infection; Drug Costs; Drug Prescriptions; Drug Resistance, Bacterial; Drug Utilization; Escherichia; Health Policy; Hospitals; Humans; Imipenem; Klebsiella; Meropenem; Methicillin Resistance; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Pseudomonas; Staphylococcus aureus; Teicoplanin; Thienamycins; Turkey; Vancomycin | 2011 |
Recommended β-lactam regimens are inadequate in septic patients treated with continuous renal replacement therapy.
Topics: Aged; Anti-Bacterial Agents; beta-Lactams; Cefepime; Ceftazidime; Cephalosporins; Dose-Response Relationship, Drug; Female; Humans; Intensive Care Units; Male; Meropenem; Microbial Sensitivity Tests; Middle Aged; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Practice Guidelines as Topic; Prospective Studies; Pseudomonas aeruginosa; Renal Replacement Therapy; Shock, Septic; Thienamycins | 2011 |
Ionization constants and solubility of compounds involved in enzymatic synthesis of aminopenicillins and aminocephalosporins.
Topics: Amino Acids; beta-Lactams; Cephalosporins; Chemistry, Pharmaceutical; Drug Design; Electrolytes; Hydrogen-Ion Concentration; Ions; Models, Chemical; Models, Theoretical; Penicillanic Acid; Penicillins; Solubility; Temperature; Thermodynamics | 2011 |
[Cefepime versus piperacillin/tazobactam with or without amikacin in the treatment of febrile hematological and oncological neutropenic patients in an internal medicine ward].
Topics: Adult; Aged; Amikacin; Anti-Bacterial Agents; Cefepime; Cephalosporins; Drug Therapy, Combination; Female; Fever; Hematologic Neoplasms; Humans; Male; Middle Aged; Neoplasms; Neutropenia; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Retrospective Studies; Risk Factors; Treatment Outcome | 2010 |
In vivo comparison of CXA-101 (FR264205) with and without tazobactam versus piperacillin-tazobactam using human simulated exposures against phenotypically diverse gram-negative organisms.
Topics: Animals; Anti-Bacterial Agents; beta-Lactamases; Cephalosporins; Colony Count, Microbial; Disease Models, Animal; Drug Combinations; Drug Resistance, Bacterial; Escherichia coli; Escherichia coli Infections; Female; Humans; Klebsiella Infections; Klebsiella pneumoniae; Mice; Mice, Inbred ICR; Microbial Sensitivity Tests; Penicillanic Acid; Phenotype; Piperacillin; Piperacillin, Tazobactam Drug Combination; Pseudomonas aeruginosa; Pseudomonas Infections; Tazobactam; Thigh | 2012 |
Changes in the use of broad-spectrum antibiotics after cefepime shortage: a time series analysis.
Topics: Anti-Bacterial Agents; Cefepime; Cephalosporins; Drug Resistance, Bacterial; Drug Utilization; Health Policy; Hospitals; Humans; Meropenem; Microbial Sensitivity Tests; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Policy; Pseudomonas aeruginosa; Switzerland; Thienamycins; Time Factors | 2012 |
First-line treatment with cephalosporins in spontaneous bacterial peritonitis provides poor antibiotic coverage.
Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Ascitic Fluid; Cephalosporins; Denmark; Drug Resistance, Bacterial; Escherichia coli; Escherichia coli Infections; Female; Gram-Positive Bacterial Infections; Gram-Positive Cocci; Humans; Kaplan-Meier Estimate; Liver Cirrhosis; Male; Meropenem; Middle Aged; Mycoses; Penicillanic Acid; Peritonitis; Piperacillin; Piperacillin, Tazobactam Drug Combination; Retrospective Studies; Thienamycins | 2012 |
Correlation between levofloxacin consumption and the incidence of nosocomial infections due to fluoroquinolone-resistant Escherichia coli.
Topics: Anti-Bacterial Agents; Carbapenems; Cephalosporins; Cross Infection; Drug Resistance, Multiple, Bacterial; Escherichia coli; Escherichia coli Infections; Humans; Levofloxacin; Microbial Sensitivity Tests; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination | 2016 |
Extended-spectrum β-lactamase producers reported as susceptible to piperacillin-tazobactam, cefepime, and cefuroxime in the era of lowered breakpoints and no confirmatory tests.
Topics: Anti-Bacterial Agents; beta-Lactamases; Cefepime; Cefuroxime; Cephalosporins; Escherichia coli; Humans; Klebsiella pneumoniae; Microbial Sensitivity Tests; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination | 2012 |
The ecology of antibiotic use in the ICU: homogeneous prescribing of cefepime but not tazocin selects for antibiotic resistant infection.
Topics: Adult; Aged; Anti-Bacterial Agents; Cefepime; Cephalosporins; Drug Prescriptions; Drug Resistance, Bacterial; Female; Humans; Intensive Care Units; Length of Stay; Male; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Middle Aged; Nasopharynx; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Pseudomonas aeruginosa; Pseudomonas Infections; Staphylococcal Infections; Survival Rate | 2012 |
Empiric antibiotics pending bronchoalveolar lavage data in patients without pneumonia significantly alters the flora, but not the resistance profile, if a subsequent pneumonia develops.
Topics: Acetamides; Anti-Bacterial Agents; Bronchoalveolar Lavage; Bronchoalveolar Lavage Fluid; Cefepime; Cephalosporins; Drug Resistance, Bacterial; Drug Therapy, Combination; Female; Gram-Negative Bacteria; Gram-Negative Bacterial Infections; Gram-Positive Bacteria; Gram-Positive Bacterial Infections; Humans; Linezolid; Male; Microbial Sensitivity Tests; Middle Aged; Oxazolidinones; Penicillanic Acid; Piperacillin; Pneumonia, Ventilator-Associated; Retrospective Studies; Tazobactam; Treatment Outcome; Vancomycin; Wounds and Injuries | 2013 |
AmpC β-lactamases in nosocomial isolates of Klebsiella pneumoniae from India.
Topics: Anti-Bacterial Agents; Bacterial Proteins; beta-Lactamase Inhibitors; beta-Lactamases; Cefepime; Cephalosporins; Cross Infection; Drug Resistance, Bacterial; Humans; India; Klebsiella pneumoniae; Microbial Sensitivity Tests; Penicillanic Acid; Tazobactam | 2012 |
Antimicrobial susceptibility pattern and distribution of exoU and exoS in clinical isolates of Pseudomonas aeruginosa at a Malaysian hospital.
Topics: ADP Ribose Transferases; Adult; Anti-Bacterial Agents; Bacterial Proteins; Bacterial Toxins; Cefepime; Ceftazidime; Cephalosporins; Chi-Square Distribution; Ciprofloxacin; Drug Resistance, Multiple, Bacterial; Female; Gentamicins; Hospitals; Humans; Malaysia; Male; Microbial Sensitivity Tests; Middle Aged; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Polymerase Chain Reaction; Pseudomonas aeruginosa | 2012 |
Case-control study of drug monitoring of β-lactams in obese critically ill patients.
Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Bacterial Infections; beta-Lactams; Case-Control Studies; Cefepime; Ceftazidime; Cephalosporins; Drug Monitoring; Enzyme Inhibitors; Female; Humans; Male; Meropenem; Middle Aged; Obesity; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Renal Replacement Therapy; Sepsis; Shock, Septic; Tazobactam; Thienamycins; Young Adult | 2013 |
In vivo activities of ceftolozane, a new cephalosporin, with and without tazobactam against Pseudomonas aeruginosa and Enterobacteriaceae, including strains with extended-spectrum β-lactamases, in the thighs of neutropenic mice.
Topics: Animals; Anti-Bacterial Agents; beta-Lactamases; Cephalosporins; Enterobacteriaceae; Female; Mice; Mice, Inbred ICR; Microbial Sensitivity Tests; Penicillanic Acid; Pseudomonas aeruginosa; Pseudomonas Infections; Tazobactam; Thigh | 2013 |
Pharmacokinetics-pharmacodynamics of tazobactam in combination with ceftolozane in an in vitro infection model.
Topics: Anti-Bacterial Agents; Area Under Curve; beta-Lactamases; Cephalosporins; Dose-Response Relationship, Drug; Drug Therapy, Combination; Escherichia coli; Escherichia coli Infections; Humans; Microbial Sensitivity Tests; Models, Biological; Molecular Sequence Data; Penicillanic Acid; Real-Time Polymerase Chain Reaction; Sequence Analysis, DNA; Tazobactam | 2013 |
New insights in the production of aerosol antibiotics. Evaluation of the optimal aerosol production system for ampicillin-sulbactam, meropenem, ceftazidime, cefepime and piperacillin-tazobactam.
Topics: Aerosols; Ampicillin; Anti-Bacterial Agents; Cefepime; Ceftazidime; Cephalosporins; Chemistry, Pharmaceutical; Equipment Design; Meropenem; Nebulizers and Vaporizers; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Sulbactam; Thienamycins | 2013 |
In vitro activity of ceftolozane-tazobactam against Pseudomonas aeruginosa isolates obtained from patients in Canadian hospitals in the CANWARD study, 2007 to 2012.
Topics: Anti-Bacterial Agents; Canada; Ceftazidime; Cephalosporins; Cross Infection; Drug Combinations; Drug Resistance, Multiple, Bacterial; Hospitals; Humans; Microbial Sensitivity Tests; Penicillanic Acid; Pseudomonas aeruginosa; Pseudomonas Infections; Retrospective Studies; Tazobactam | 2013 |
Pharmacological basis of β-lactamase inhibitor therapeutics: tazobactam in combination with Ceftolozane.
Topics: Anti-Bacterial Agents; beta-Lactamases; Cephalosporins; Colony Count, Microbial; Computer Simulation; Drug Administration Schedule; Drug Combinations; Drug Dosage Calculations; Escherichia coli; Escherichia coli Infections; Gene Expression; Half-Life; Humans; Klebsiella Infections; Klebsiella pneumoniae; Microbial Sensitivity Tests; Models, Statistical; Penicillanic Acid; Plasmids; Tazobactam | 2013 |
Antimicrobial activity of ceftolozane-tazobactam tested against Enterobacteriaceae and Pseudomonas aeruginosa with various resistance patterns isolated in U.S. Hospitals (2011-2012).
Topics: Anti-Infective Agents; Cephalosporins; Drug Resistance, Multiple, Bacterial; Enterobacteriaceae; Hospitals; Humans; Microbial Sensitivity Tests; Penicillanic Acid; Pseudomonas aeruginosa; Tazobactam; United States | 2013 |
Acute renal failure associated with vancomycin and β-lactams for the treatment of osteomyelitis in diabetics: piperacillin-tazobactam as compared with cefepime.
Topics: Acute Kidney Injury; Anti-Bacterial Agents; Cefepime; Cephalosporins; Cohort Studies; Diabetes Complications; Drug Therapy, Combination; Humans; Incidence; Middle Aged; Osteomyelitis; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Retrospective Studies; Vancomycin | 2014 |
Postoperative bacteriuria, pyuria and urinary tract infection in patients with an orthotopic sigmoid colon neobladder replacement.
Topics: Aged; Anti-Bacterial Agents; Bacteriuria; Cefepime; Cephalosporins; Colon, Sigmoid; Cystectomy; Drug Resistance, Multiple, Bacterial; Enterococcus; Escherichia coli; Female; Humans; Klebsiella pneumoniae; Leukocyte Count; Levofloxacin; Male; Meropenem; Middle Aged; Penicillanic Acid; Piperacillin; Postoperative Complications; Prevalence; Pyuria; Staphylococcus aureus; Sulfamethoxazole; Tazobactam; Thienamycins; Trimethoprim; Urinary Diversion; Urinary Tract Infections | 2014 |
Activity of ceftolozane-tazobactam against a broad spectrum of recent clinical anaerobic isolates.
Topics: Anaerobiosis; Anti-Bacterial Agents; Bacteroides fragilis; Cephalosporins; Clostridium; Drug Combinations; Fusobacterium; Gram-Negative Bacterial Infections; Gram-Positive Bacterial Infections; Gram-Positive Cocci; Humans; Microbial Sensitivity Tests; Penicillanic Acid; Prevotella; Propionibacterium; Tazobactam | 2014 |
Reliability-targeted HPLC-UV method validation--a protocol enrichment perspective.
Topics: Bayes Theorem; Cefepime; Cephalosporins; Chromatography, High Pressure Liquid; Humans; Penicillanic Acid; Reproducibility of Results; Ritonavir; Spectrophotometry, Ultraviolet; Tazobactam | 2014 |
A multicenter case-case control study for risk factors and outcomes of extensively drug-resistant Acinetobacter baumannii bacteremia.
Topics: Acinetobacter baumannii; Acinetobacter Infections; Anti-Bacterial Agents; Bacteremia; Carbapenems; Case-Control Studies; Central Venous Catheters; Cephalosporins; Coinfection; Drug Resistance, Bacterial; Female; Humans; Male; Microbial Sensitivity Tests; Neoplasms; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Polymyxin B; Respiratory Tract Infections; Risk Factors; Severity of Illness Index; Treatment Outcome | 2014 |
Post-β-lactamase-inhibitor effect of tazobactam in combination with ceftolozane on extended-spectrum-β-lactamase-producing strains.
Topics: Anti-Bacterial Agents; beta-Lactamases; Cephalosporins; Escherichia coli; Microbial Sensitivity Tests; Penicillanic Acid; Tazobactam | 2014 |
Impact of renal function on the pharmacokinetics and safety of ceftolozane-tazobactam.
Topics: Adolescent; Adult; Aged; Cephalosporins; Female; Humans; Kidney Failure, Chronic; Male; Middle Aged; Penicillanic Acid; Prospective Studies; Tazobactam; Young Adult | 2014 |
Pseudomonas aeruginosa ceftolozane-tazobactam resistance development requires multiple mutations leading to overexpression and structural modification of AmpC.
Topics: Anti-Bacterial Agents; Bacterial Proteins; beta-Lactamases; Ceftazidime; Cephalosporins; Imipenem; Meropenem; Microbial Sensitivity Tests; Mutation; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Pseudomonas aeruginosa; Pseudomonas Infections; Tazobactam; Thienamycins | 2014 |
Comparative evaluation of six phenotypic methods for detecting extended-spectrum beta-lactamase-producing Enterobacteriaceae.
Topics: Amoxicillin-Potassium Clavulanate Combination; Anti-Bacterial Agents; Bacterial Typing Techniques; beta-Lactamases; beta-Lactams; Cefepime; Cefotaxime; Ceftazidime; Cephalosporins; Enterobacteriaceae; False Negative Reactions; False Positive Reactions; Female; Humans; India; Male; Microbial Sensitivity Tests; Penicillanic Acid; Phenotype; Piperacillin; Piperacillin, Tazobactam Drug Combination; Predictive Value of Tests | 2014 |
Comparison of acute kidney injury during treatment with vancomycin in combination with piperacillin-tazobactam or cefepime.
Topics: Acute Kidney Injury; Adult; Aged; Anti-Bacterial Agents; Cefepime; Cephalosporins; Cohort Studies; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Retrospective Studies; Treatment Outcome; Vancomycin | 2014 |
Antimicrobial activity of cefepime-tazobactam combination tested against clinical isolates of Enterobacteriaceae.
Topics: Anti-Bacterial Agents; Cefepime; Cephalosporins; Drug Resistance, Bacterial; Drug Therapy, Combination; Enterobacteriaceae; Humans; India; Penicillanic Acid; Tazobactam | 2014 |
Ceftolozane/tazobactam activity tested against aerobic Gram-negative organisms isolated from intra-abdominal and urinary tract infections in European and United States hospitals (2012).
Topics: Anti-Bacterial Agents; beta-Lactam Resistance; beta-Lactamases; Cephalosporins; Citrobacter; Cross Infection; Drug Resistance, Multiple, Bacterial; Enterobacter; Escherichia coli; Europe; Gram-Negative Aerobic Bacteria; Humans; Intraabdominal Infections; Klebsiella oxytoca; Klebsiella pneumoniae; Microbial Sensitivity Tests; Penicillanic Acid; Proteus mirabilis; Pseudomonas aeruginosa; Serratia; Tazobactam; United States; Urinary Tract Infections | 2014 |
Ceftolozane/tazobactam activity tested against Gram-negative bacterial isolates from hospitalised patients with pneumonia in US and European medical centres (2012).
Topics: Academic Medical Centers; Anti-Bacterial Agents; Cephalosporins; Cross Infection; Europe; Gram-Negative Bacteria; Gram-Negative Bacterial Infections; Humans; Microbial Sensitivity Tests; Penicillanic Acid; Pneumonia, Bacterial; Tazobactam; United States | 2014 |
Epidemic and virulence characteristic of Shigella spp. with extended-spectrum cephalosporin resistance in Xiaoshan District, Hangzhou, China.
Topics: Adolescent; Adult; Anti-Bacterial Agents; beta-Lactamases; Cefepime; Cephalosporin Resistance; Cephalosporins; Child; Child, Preschool; China; Ciprofloxacin; Dysentery, Bacillary; Female; Galanin; Genes, Bacterial; Genotype; Humans; Male; Microbial Sensitivity Tests; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Polymerase Chain Reaction; Shigella; Substance P; Virulence | 2014 |
Antimicrobial activity of ceftolozane/tazobactam tested against Pseudomonas aeruginosa and Enterobacteriaceae with various resistance patterns isolated in European hospitals (2011-12).
Topics: Anti-Bacterial Agents; beta-Lactam Resistance; beta-Lactamase Inhibitors; Cephalosporins; Cross Infection; Enterobacteriaceae; Enterobacteriaceae Infections; Europe; Genotype; Humans; Microbial Sensitivity Tests; Penicillanic Acid; Pseudomonas aeruginosa; Pseudomonas Infections; Tazobactam | 2014 |
[Mechanism of drug resistance of carbapenems-resistant Acinetobacter baumannii and the application of a combination of drugs in vitro].
Topics: Acinetobacter baumannii; Acinetobacter Infections; Ampicillin; Anti-Bacterial Agents; beta-Lactamase Inhibitors; Carbapenems; Cefepime; Cephalosporins; Drug Resistance; Humans; In Vitro Techniques; Meropenem; Microbial Sensitivity Tests; Penicillanic Acid; Pharmaceutical Preparations; Piperacillin; Piperacillin, Tazobactam Drug Combination; Sulbactam; Thienamycins | 2014 |
Relationship between ceftolozane-tazobactam exposure and selection for Pseudomonas aeruginosa resistance in a hollow-fiber infection model.
Topics: Anti-Bacterial Agents; Cephalosporins; Microbial Sensitivity Tests; Penicillanic Acid; Pseudomonas aeruginosa; Tazobactam | 2014 |
Clinical manifestations and prognostic factors of Morganella morganii bacteremia.
Topics: Age Factors; Aged; Aged, 80 and over; Ampicillin; Anti-Bacterial Agents; Bacteremia; Cephalosporins; Community-Acquired Infections; Cross Infection; Drug Resistance, Bacterial; Enterobacteriaceae Infections; Female; Gentamicins; Humans; Male; Microbial Sensitivity Tests; Middle Aged; Morganella morganii; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Risk Factors; Taiwan | 2015 |
In vivo efficacy of ceftolozane against Pseudomonas aeruginosa in a rabbit experimental model of pneumonia: comparison with ceftazidime, piperacillin/tazobactam and imipenem.
Topics: Animal Structures; Animals; Anti-Bacterial Agents; Bacterial Load; Ceftazidime; Cephalosporins; Colony Count, Microbial; Disease Models, Animal; Female; Humans; Imipenem; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Pneumonia, Bacterial; Pseudomonas aeruginosa; Pseudomonas Infections; Rabbits; Treatment Outcome | 2014 |
In vitro activity of ceftolozane-tazobactam as determined by broth dilution and agar diffusion assays against recent U.S. Escherichia coli isolates from 2010 to 2011 carrying CTX-M-type extended-spectrum β-lactamases.
Topics: Anti-Bacterial Agents; Cephalosporins; Escherichia coli; Escherichia coli Infections; Humans; Microbial Sensitivity Tests; Penicillanic Acid; Tazobactam; United States | 2014 |
Mutation-driven β-lactam resistance mechanisms among contemporary ceftazidime-nonsusceptible Pseudomonas aeruginosa isolates from U.S. hospitals.
Topics: Anti-Bacterial Agents; Bacterial Outer Membrane Proteins; Bacterial Proteins; beta-Lactam Resistance; beta-Lactamases; Cefepime; Ceftazidime; Cephalosporins; Cross Infection; Gene Expression Regulation, Bacterial; Humans; Membrane Transport Proteins; Microbial Sensitivity Tests; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Porins; Pseudomonas aeruginosa; Pseudomonas Infections | 2014 |
Quantification of piperacillin, tazobactam, cefepime, meropenem, ciprofloxacin and linezolid in serum using an isotope dilution UHPLC-MS/MS method with semi-automated sample preparation.
Topics: Analytic Sample Preparation Methods; Anti-Bacterial Agents; Automation; Blood Chemical Analysis; Cefepime; Cephalosporins; Chromatography, High Pressure Liquid; Ciprofloxacin; Humans; Isotopes; Linezolid; Meropenem; Penicillanic Acid; Piperacillin; Tandem Mass Spectrometry; Tazobactam; Thienamycins; Time Factors | 2015 |
Extended-spectrum β-lactamase-producing Escherichia coli and Klebsiella pneumoniae bacteremia in febrile neutropenic children.
Topics: Aminoglycosides; Anti-Bacterial Agents; Bacteremia; beta-Lactamases; Cefepime; Cephalosporins; Child; Escherichia coli; Escherichia coli Infections; Febrile Neutropenia; Female; Humans; Klebsiella Infections; Klebsiella pneumoniae; Male; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Retrospective Studies | 2015 |
A single-center evaluation of the risk for colonization or bacteremia with piperacillin-tazobactam- and cefepime-resistant bacteria in patients with acute leukemia receiving fluoroquinolone prophylaxis.
Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Bacteremia; Cefepime; Cephalosporins; Drug Resistance, Bacterial; Female; Fluoroquinolones; Humans; Leukemia; Male; Middle Aged; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Post-Exposure Prophylaxis; Random Allocation; Retrospective Studies; Risk Factors; Young Adult | 2016 |
Ceftolozane/tazobactam for the treatment of complicated urinary tract and intra-abdominal infections.
Topics: Animals; beta-Lactamase Inhibitors; Cephalosporins; Clinical Trials as Topic; Enterobacteriaceae; Escherichia coli; Gram-Negative Bacterial Infections; Humans; Intraabdominal Infections; Investigational New Drug Application; Klebsiella Infections; Klebsiella pneumoniae; Microbial Sensitivity Tests; Penicillanic Acid; Pseudomonas aeruginosa; Tazobactam; Treatment Outcome; Urinary Tract Infections | 2015 |
Plasma and epithelial lining fluid pharmacokinetics of ceftolozane and tazobactam alone and in combination in mice.
Topics: Animals; Anti-Bacterial Agents; Cephalosporins; Escherichia coli; Female; Klebsiella pneumoniae; Mice; Penicillanic Acid; Protein Binding; Tazobactam; Thigh | 2015 |
A new ASPECT for complicated urinary tract infections.
Topics: Anti-Infective Agents, Urinary; Cephalosporins; Female; Gram-Negative Bacterial Infections; Gram-Positive Bacterial Infections; Humans; Levofloxacin; Male; Penicillanic Acid; Urinary Tract Infections | 2015 |
Infection: Ceftolozane-tazobactam gives a new ASPECT to the fight against antimicrobial resistance.
Topics: Anti-Infective Agents, Urinary; Cephalosporins; Female; Gram-Negative Bacterial Infections; Gram-Positive Bacterial Infections; Humans; Levofloxacin; Male; Penicillanic Acid; Urinary Tract Infections | 2015 |
In Vitro Activity of Ceftolozane Alone and in Combination with Tazobactam against Extended-Spectrum-β-Lactamase-Harboring Enterobacteriaceae.
Topics: Anti-Bacterial Agents; beta-Lactamases; Cephalosporins; Drug Therapy, Combination; Enterobacteriaceae; Enterobacteriaceae Infections; Humans; Microbial Sensitivity Tests; Penicillanic Acid; Tazobactam | 2015 |
Ceftolozane/Tazobactam Therapy of Respiratory Infections due to Multidrug-Resistant Pseudomonas aeruginosa.
Topics: Aged; Anti-Bacterial Agents; Cephalosporins; Drug Resistance, Multiple, Bacterial; Humans; Male; Microbial Sensitivity Tests; Middle Aged; Penicillanic Acid; Pneumonia, Ventilator-Associated; Pseudomonas aeruginosa; Pseudomonas Infections; Tazobactam; Treatment Outcome | 2015 |
A green capillary zone electrophoresis method for the simultaneous determination of piperacillin, tazobactam and cefepime in pharmaceutical formulations and human plasma.
Topics: Cefepime; Cephalosporins; Dosage Forms; Electrophoresis, Capillary; Green Chemistry Technology; Humans; Linear Models; Penicillanic Acid; Piperacillin; Reproducibility of Results; Sensitivity and Specificity; Tazobactam | 2015 |
Susceptibility Profile of Ceftolozane/Tazobactam and Other Parenteral Antimicrobials Against Escherichia coli, Klebsiella pneumoniae, and Pseudomonas aeruginosa From US Hospitals.
Topics: Adult; Anti-Infective Agents; beta-Lactamases; Cefepime; Cephalosporins; Cross Infection; Dose-Response Relationship, Drug; Drug Resistance, Bacterial; Enterobacteriaceae; Escherichia coli; Hospitals; Humans; Klebsiella pneumoniae; Microbial Sensitivity Tests; Penicillanic Acid; Piperacillin; Pseudomonas aeruginosa; Tazobactam; United States | 2015 |
Mutations in β-Lactamase AmpC Increase Resistance of Pseudomonas aeruginosa Isolates to Antipseudomonal Cephalosporins.
Topics: Adaptation, Physiological; Amino Acid Sequence; Amino Acid Substitution; Anti-Bacterial Agents; Aztreonam; Bacterial Proteins; beta-Lactam Resistance; beta-Lactamases; Cefepime; Ceftazidime; Cephalosporins; Gene Expression; Microbial Sensitivity Tests; Molecular Sequence Data; Mutation; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Protein Structure, Secondary; Protein Structure, Tertiary; Pseudomonas aeruginosa; Tazobactam; Ticarcillin | 2015 |
Ceftolozane-tazobactam activity against phylogenetically diverse Clostridium difficile strains.
Topics: Anti-Bacterial Agents; Cephalosporins; Clostridioides difficile; Microbial Sensitivity Tests; Penicillanic Acid; Phylogeny; Tazobactam | 2015 |
In vitro activity of ceftolozane/tazobactam against clinical isolates of Pseudomonas aeruginosa and Enterobacteriaceae recovered in Spanish medical centres: Results of the CENIT study.
Topics: Academic Medical Centers; Anti-Bacterial Agents; Cephalosporins; Enterobacteriaceae; Enterobacteriaceae Infections; Humans; Microbial Sensitivity Tests; Penicillanic Acid; Prospective Studies; Pseudomonas aeruginosa; Pseudomonas Infections; Spain; Tazobactam | 2015 |
Ceftolozane-tazobactam versus levofloxacin in urinary tract infection.
Topics: Anti-Infective Agents, Urinary; Cephalosporins; Female; Gram-Negative Bacterial Infections; Gram-Positive Bacterial Infections; Humans; Levofloxacin; Male; Penicillanic Acid; Urinary Tract Infections | 2015 |
Ceftolozane-tazobactam versus levofloxacin in urinary tract infection.
Topics: Anti-Infective Agents, Urinary; Cephalosporins; Female; Gram-Negative Bacterial Infections; Gram-Positive Bacterial Infections; Humans; Levofloxacin; Male; Penicillanic Acid; Urinary Tract Infections | 2015 |
Ceftolozane-tazobactam versus levofloxacin in urinary tract infection.
Topics: Anti-Infective Agents, Urinary; Cephalosporins; Female; Gram-Negative Bacterial Infections; Gram-Positive Bacterial Infections; Humans; Levofloxacin; Male; Penicillanic Acid; Urinary Tract Infections | 2015 |
Ceftolozane-tazobactam versus levofloxacin in urinary tract infection - Authors' reply.
Topics: Anti-Infective Agents, Urinary; Cephalosporins; Female; Gram-Negative Bacterial Infections; Gram-Positive Bacterial Infections; Humans; Levofloxacin; Male; Penicillanic Acid; Urinary Tract Infections | 2015 |
Noninferiority Doesn't Mean Not Inferior.
Topics: Anti-Bacterial Agents; Bacterial Infections; Cephalosporins; Drug Resistance, Multiple, Bacterial; Female; Humans; Intraabdominal Infections; Male; Metronidazole; Penicillanic Acid | 2016 |
Response to Spellberg and Brass.
Topics: Anti-Bacterial Agents; Bacterial Infections; Cephalosporins; Drug Resistance, Multiple, Bacterial; Female; Humans; Intraabdominal Infections; Male; Metronidazole; Penicillanic Acid | 2016 |
Pharmacodynamics of Ceftolozane plus Tazobactam Studied in an In Vitro Pharmacokinetic Model of Infection.
Topics: Anti-Bacterial Agents; Bacterial Proteins; beta-Lactamases; Bioreactors; Cephalosporins; Chromatography, High Pressure Liquid; Colony Count, Microbial; Computer Simulation; Escherichia coli; Gene Expression; Half-Life; Infusion Pumps; Microbial Sensitivity Tests; Models, Statistical; Penicillanic Acid; Porins; Pseudomonas aeruginosa; Tazobactam | 2016 |
Silver- and fluoride-containing mesoporous bioactive glasses versus commonly used antibiotics: Activity against multidrug-resistant bacterial strains isolated from patients with burns.
Topics: Amikacin; Animals; Anti-Bacterial Agents; Aztreonam; Burns; Carbenicillin; Cefepime; Ceftazidime; Ceftriaxone; Cell Survival; Cephalosporins; Ciprofloxacin; Drug Resistance, Multiple, Bacterial; Fluorides; Gentamicins; Glass; Humans; Imipenem; Meropenem; Mice; Microbial Sensitivity Tests; NIH 3T3 Cells; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Pseudomonas aeruginosa; Silver; Thienamycins; Tobramycin; Wound Infection | 2016 |
Evaluation of CTX-M steady-state mRNA, mRNA half-life and protein production in various STs of Escherichia coli.
Topics: Anti-Bacterial Agents; beta-Lactamases; Cephalosporins; Disk Diffusion Antimicrobial Tests; Escherichia coli; Genotype; Humans; Immunoblotting; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA Stability; RNA, Messenger; Tazobactam | 2016 |
Prescribing Ceftolozane/Tazobactam for Pediatric Patients: Current Status and Future Implications.
Topics: Anti-Bacterial Agents; Cephalosporins; Child; Humans; Intraabdominal Infections; Penicillanic Acid; Tazobactam | 2016 |
Ceftolozane-Tazobactam Pharmacokinetics in a Critically Ill Patient on Continuous Venovenous Hemofiltration.
Topics: Anti-Bacterial Agents; Cephalosporins; Critical Illness; Drug Resistance, Multiple, Bacterial; Hemofiltration; Humans; Intensive Care Units; Male; Microbial Sensitivity Tests; Middle Aged; Penicillanic Acid; Prospective Studies; Prosthesis-Related Infections; Pseudomonas aeruginosa; Pseudomonas Infections; Tazobactam | 2015 |
Combinatorial Pharmacodynamics of Ceftolozane-Tazobactam against Genotypically Defined β-Lactamase-Producing Escherichia coli: Insights into the Pharmacokinetics/Pharmacodynamics of β-Lactam-β-Lactamase Inhibitor Combinations.
Topics: Anti-Bacterial Agents; Bacterial Proteins; beta-Lactamases; Cephalosporins; Computer Simulation; Dose-Response Relationship, Drug; Escherichia coli; Gene Expression; Microbial Sensitivity Tests; Models, Statistical; Penicillanic Acid; Tazobactam | 2016 |
Characterization of VCC-1, a Novel Ambler Class A Carbapenemase from Vibrio cholerae Isolated from Imported Retail Shrimp Sold in Canada.
Topics: Amino Acid Sequence; Animals; Aztreonam; Bacterial Proteins; Base Sequence; beta-Lactamases; Canada; Carbapenems; Cephalosporins; Clavulanic Acid; Drug Resistance, Multiple, Bacterial; Genome, Bacterial; Humans; Microbial Sensitivity Tests; Penaeidae; Penicillanic Acid; Penicillins; Seafood; Sequence Alignment; Sequence Analysis, DNA; Tazobactam; Vibrio cholerae | 2016 |
Prospective Comparison of Acute Kidney Injury During Treatment With the Combination of Piperacillin-Tazobactam and Vancomycin Versus the Combination of Cefepime or Meropenem and Vancomycin.
Topics: Acute Kidney Injury; Aged; Aged, 80 and over; Anti-Bacterial Agents; Cefepime; Cephalosporins; Cohort Studies; Drug Therapy, Combination; Female; Humans; Male; Meropenem; Middle Aged; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Prospective Studies; Thienamycins; Treatment Outcome; Vancomycin | 2017 |
Comparative Incidence of Acute Kidney Injury in Critically Ill Patients Receiving Vancomycin with Concomitant Piperacillin-Tazobactam or Cefepime: A Retrospective Cohort Study.
Topics: Acute Kidney Injury; Anti-Bacterial Agents; Arkansas; Cefepime; Cephalosporins; Critical Illness; Drug Therapy, Combination; Female; Humans; Incidence; Male; Middle Aged; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Retrospective Studies; Vancomycin | 2016 |
Evaluation of the In Vitro Activity of Ceftazidime-Avibactam and Ceftolozane-Tazobactam against Meropenem-Resistant Pseudomonas aeruginosa Isolates.
Topics: Azabicyclo Compounds; Ceftazidime; Cephalosporins; Drug Combinations; Drug Resistance, Bacterial; Meropenem; Microbial Sensitivity Tests; Penicillanic Acid; Pseudomonas aeruginosa; Tazobactam; Thienamycins | 2016 |
Development of an HPLC Method for the Determination of Ceftolozane/Tazobactam in Biological and Aqueous Matrixes.
Topics: Animals; Anti-Bacterial Agents; Cephalosporins; Chemistry Techniques, Analytical; Chromatography, High Pressure Liquid; Humans; Penicillanic Acid; Plasma; Reproducibility of Results; Sodium Chloride; Swine; Tazobactam | 2016 |
Daptomycin in Combination with Ceftolozane-Tazobactam or Cefazolin against Daptomycin-Susceptible and -Nonsusceptible Staphylococcus aureus in an In Vitro, Hollow-Fiber Model.
Topics: Anti-Bacterial Agents; Cefazolin; Cephalosporins; Daptomycin; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Penicillanic Acid; Staphylococcus aureus; Tazobactam | 2016 |
In Vivo and In Vitro Efficacy of Minocycline-Based Combination Therapy for Minocycline-Resistant Acinetobacter baumannii.
Topics: Acinetobacter baumannii; Acinetobacter Infections; Animals; Anti-Bacterial Agents; Biofilms; Cefepime; Cephalosporins; Colistin; Drug Resistance, Multiple, Bacterial; Gentamicins; Imipenem; Meropenem; Mice; Microbial Sensitivity Tests; Minocycline; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Pneumonia; Taiwan; Thienamycins | 2016 |
In vitro activity of ceftolozane/tazobactam against clinical isolates of Pseudomonas aeruginosa in the planktonic and biofilm states.
Topics: Anti-Infective Agents, Urinary; beta-Lactamase Inhibitors; Biofilms; Cephalosporins; Humans; Microbial Sensitivity Tests; Penicillanic Acid; Pseudomonas aeruginosa; Pseudomonas Infections; Tazobactam | 2016 |
Use of Ceftolozane/Tazobactam in the Treatment of Multidrug-resistant Pseudomonas aeruginosa Bloodstream Infection in a Pediatric Leukemia Patient.
Topics: Anti-Bacterial Agents; Bacteremia; Cephalosporins; Child; Drug Resistance, Multiple, Bacterial; Hospitalization; Humans; Leukemia; Male; Penicillanic Acid; Pseudomonas aeruginosa; Pseudomonas Infections; Tazobactam | 2016 |
Impact of computerized pre-authorization of broad spectrum antibiotics in Pseudomonas aeruginosa at a children's hospital in Japan.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Carbapenems; Cefepime; Ceftazidime; Cephalosporins; Hospitals; Humans; Japan; Microbial Sensitivity Tests; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Pseudomonas aeruginosa; Pseudomonas Infections; Tokyo | 2016 |
ESBL E coli and P. aeruginosa Resistance to Ceftolozane-Tazobactam in a Patient with a Liver Abscess. The Search for an Omnipotent Antibiotic Goes On!
Topics: Anti-Bacterial Agents; beta-Lactamases; Cephalosporins; Drug Resistance, Multiple, Bacterial; Escherichia coli; Female; Humans; Liver Abscess; Microbial Sensitivity Tests; Middle Aged; Penicillanic Acid; Pseudomonas aeruginosa; Tazobactam | 2018 |
Treatment of multidrug-resistant Pseudomonas aeruginosa with ceftolozane/tazobactam in a critically ill patient receiving continuous venovenous haemodiafiltration.
Topics: Aged; Anti-Infective Agents, Urinary; beta-Lactamase Inhibitors; Cephalosporins; Chromatography, High Pressure Liquid; Critical Illness; Drug Resistance, Multiple, Bacterial; Hemofiltration; Humans; Male; Penicillanic Acid; Plasma; Pseudomonas aeruginosa; Pseudomonas Infections; Tazobactam; Treatment Outcome; United States | 2016 |
Successful Use of Ceftolozane-Tazobactam to Treat a Pulmonary Exacerbation of Cystic Fibrosis Caused by Multidrug-Resistant Pseudomonas aeruginosa.
Topics: Adult; Anti-Bacterial Agents; Cephalosporins; Cystic Fibrosis; Drug Resistance, Multiple, Bacterial; Humans; Male; Microbial Sensitivity Tests; Penicillanic Acid; Pseudomonas aeruginosa; Pseudomonas Infections; Tazobactam; Treatment Outcome | 2016 |
What is the role of the new β-lactam/β-lactamase inhibitors ceftolozane/tazobactam and ceftazidime/avibactam?
Topics: Anti-Bacterial Agents; Azabicyclo Compounds; beta-Lactamase Inhibitors; beta-Lactams; Ceftazidime; Cephalosporins; Drug Combinations; Drug Resistance, Multiple, Bacterial; Enterobacteriaceae Infections; Humans; Intraabdominal Infections; Penicillanic Acid; Pseudomonas Infections; Tazobactam; Urinary Tract Infections | 2016 |
[Study on drug sensitivity against Comamonas testosteroni by Kirby-Bauer disk diffusion method].
Topics: Anti-Bacterial Agents; Cefepime; Cephalosporins; Comamonas testosteroni; Imipenem; Meropenem; Microbial Sensitivity Tests; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Pseudomonas aeruginosa; Thienamycins | 2016 |
Successful treatment of multidrug-resistant Pseudomonas aeruginosa breakthrough bacteremia with ceftolozane/tazobactam.
Topics: Anti-Bacterial Agents; Bacteremia; Cephalosporins; Drug Resistance, Multiple, Bacterial; Humans; Male; Microbial Sensitivity Tests; Middle Aged; Off-Label Use; Penicillanic Acid; Pseudomonas aeruginosa; Pseudomonas Infections; Tazobactam | 2017 |
In Vitro-In Vivo Discordance with Humanized Piperacillin-Tazobactam Exposures against Piperacillin-Tazobactam-Resistant/Pan-β-Lactam-Susceptible Escherichia coli.
Topics: Animals; Anti-Bacterial Agents; Cephalosporins; Colistin; Culture Media; Disease Models, Animal; Drug Administration Schedule; Drug Resistance, Bacterial; Escherichia coli; Escherichia coli Infections; Female; Humans; Mice; Mice, Inbred ICR; Microbial Sensitivity Tests; Neutropenia; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Tobramycin; Treatment Outcome | 2016 |
Nephrotoxicity during Vancomycin Therapy in Combination with Piperacillin-Tazobactam or Cefepime.
Topics: Acute Kidney Injury; Adult; Aged; Anti-Bacterial Agents; Cefepime; Cephalosporins; Female; Humans; Kidney; Male; Middle Aged; Multivariate Analysis; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Retrospective Studies; Vancomycin | 2017 |
Susceptibility to cephalosporin combinations and aztreonam/avibactam among third-generation cephalosporin-resistant Enterobacteriaceae recovered on hospital admission.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Azabicyclo Compounds; Aztreonam; beta-Lactamase Inhibitors; Cephalosporin Resistance; Cephalosporins; Clavulanic Acid; Enterobacteriaceae; Enterobacteriaceae Infections; Female; Germany; Hospitals; Humans; Male; Microbial Sensitivity Tests; Middle Aged; Penicillanic Acid; Tazobactam; Young Adult | 2017 |
Salvage Therapy with Ceftolozane-Tazobactam for Multidrug-Resistant Pseudomonas aeruginosa Infections.
Topics: Adult; Aged; Anti-Bacterial Agents; Cephalosporins; Drug Resistance, Multiple, Bacterial; Female; Humans; Male; Microbial Sensitivity Tests; Middle Aged; Penicillanic Acid; Pneumonia, Bacterial; Pseudomonas aeruginosa; Pseudomonas Infections; Retrospective Studies; Salvage Therapy; Shock, Septic; Survival Analysis; Tazobactam | 2017 |
Newer Intravenous Antibiotics in the Intensive Care Unit: Ceftaroline, Ceftolozane-Tazobactam, and Ceftazidime-Avibactam.
Topics: Administration, Intravenous; Anti-Bacterial Agents; Azabicyclo Compounds; Bacterial Infections; Ceftazidime; Cephalosporins; Drug Combinations; Education, Medical, Continuing; Humans; Intensive Care Units; Penicillanic Acid; Tazobactam; United States | 2016 |
Risk of Acute Kidney Injury in Patients on Concomitant Vancomycin and Piperacillin-Tazobactam Compared to Those on Vancomycin and Cefepime.
Topics: Acute Kidney Injury; Adult; Aged; Anti-Bacterial Agents; Cefepime; Cephalosporins; Combined Modality Therapy; Drug Therapy, Combination; Female; Humans; Length of Stay; Male; Middle Aged; Odds Ratio; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Prognosis; Retrospective Studies; Risk; Severity of Illness Index; Vancomycin | 2017 |
Successful treatment of MDR Pseudomonas aeruginosa skin and soft-tissue infection with ceftolozane/tazobactam.
Topics: Anti-Infective Agents, Urinary; Cephalosporins; Drug Resistance, Multiple, Bacterial; Humans; Male; Middle Aged; Penicillanic Acid; Pseudomonas aeruginosa; Pseudomonas Infections; Skin Diseases, Bacterial; Soft Tissue Infections; Tazobactam | 2017 |
Physical compatibility of ceftolozane-tazobactam with selected i.v. drugs during simulated Y-site administration.
Topics: Anti-Bacterial Agents; Cephalosporins; Chemistry, Pharmaceutical; Drug Incompatibility; Excipients; Glucose; Humans; Infusions, Intravenous; Injections, Intravenous; Nephelometry and Turbidimetry; Penicillanic Acid; Sodium Chloride; Solubility; Tazobactam; Urinary Tract Infections | 2017 |
Susceptibility of Ceftolozane-Tazobactam and Ceftazidime-Avibactam Against a Collection of β-Lactam-Resistant Gram-Negative Bacteria.
Topics: Anti-Bacterial Agents; Azabicyclo Compounds; Bacterial Proteins; Ceftazidime; Cephalosporins; DNA, Bacterial; Drug Combinations; Drug Resistance, Bacterial; Gram-Negative Bacteria; Humans; Microbial Sensitivity Tests; Penicillanic Acid; Pseudomonas aeruginosa; Real-Time Polymerase Chain Reaction; Tazobactam | 2017 |
Antimicrobial susceptibility of Gram-negative ESKAPE pathogens isolated from hospitalized patients with intra-abdominal and urinary tract infections in Asia-Pacific countries: SMART 2013-2015.
Topics: Acinetobacter baumannii; Amikacin; Anti-Infective Agents; Asia; beta-Lactamases; beta-Lactams; Carbapenems; Cephalosporins; Drug Resistance, Multiple, Bacterial; Enterobacter; Ertapenem; Gram-Negative Bacteria; Hospitalization; Humans; Imipenem; Intraabdominal Infections; Klebsiella pneumoniae; Levofloxacin; Microbial Sensitivity Tests; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Pseudomonas aeruginosa; Urinary Tract Infections | 2017 |
Development of an algorithm for phenotypic screening of carbapenemase-producing Enterobacteriaceae in the routine laboratory.
Topics: Algorithms; Anti-Bacterial Agents; Bacterial Proteins; beta-Lactamases; beta-Lactams; Carbapenems; Cefepime; Cephalosporins; Clavulanic Acids; Drug Resistance, Bacterial; Enterobacteriaceae; Ertapenem; Humans; Imipenem; Meropenem; Microbial Sensitivity Tests; Penicillanic Acid; Penicillins; Tazobactam; Thienamycins; Ticarcillin | 2017 |
Topics: Achromobacter denitrificans; Anti-Bacterial Agents; Ceftazidime; Cephalosporins; Cystic Fibrosis; Drug Resistance, Multiple, Bacterial; Gram-Negative Bacteria; Humans; Meropenem; Microbial Sensitivity Tests; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Pseudomonas aeruginosa; Stenotrophomonas maltophilia; Tazobactam; Thienamycins | 2017 |
Ceftolozane/tazobactam activity against drug-resistant Enterobacteriaceae and Pseudomonas aeruginosa causing urinary tract and intraabdominal infections in Europe: report from an antimicrobial surveillance programme (2012-15).
Topics: Anti-Bacterial Agents; Cephalosporins; Cross Infection; Drug Resistance, Multiple, Bacterial; Enterobacteriaceae; Enterobacteriaceae Infections; Epidemiological Monitoring; Europe; Humans; Intraabdominal Infections; Israel; Microbial Sensitivity Tests; Penicillanic Acid; Pseudomonas aeruginosa; Pseudomonas Infections; Tazobactam; Turkey; Urinary Tract Infections | 2017 |
Ex vivo Ceftolozane/Tazobactam Clearance during Continuous Renal Replacement Therapy.
Topics: Animals; Anti-Bacterial Agents; Cattle; Cephalosporins; Drug Dosage Calculations; Hemodialysis Solutions; Humans; Membranes, Artificial; Metabolic Clearance Rate; Models, Biological; Penicillanic Acid; Renal Replacement Therapy; Tazobactam | 2017 |
Trends in Drug Resistance of
Topics: Acinetobacter baumannii; Amikacin; Anti-Infective Agents; Cefepime; Cefoperazone; Ceftazidime; Cephalosporins; China; Colistin; Drug Resistance, Multiple, Bacterial; Humans; Imipenem; Levofloxacin; Microbial Sensitivity Tests; Minocycline; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Sulbactam | 2017 |
Multicenter Evaluation of Ceftolozane/Tazobactam for Serious Infections Caused by Carbapenem-Resistant Pseudomonas aeruginosa.
Topics: Adult; Aged; Anti-Bacterial Agents; Carbapenems; Cephalosporins; Female; Humans; Male; Middle Aged; Penicillanic Acid; Pseudomonas aeruginosa; Pseudomonas Infections; Retrospective Studies; Tazobactam | 2017 |
Ceftolozane-tazobactam for the treatment of ventilator-associated infections by colistin-resistant Pseudomonas aeruginosa.
Topics: Acute-Phase Proteins; Aged; Anti-Bacterial Agents; Cephalosporins; Colistin; Drug Resistance, Bacterial; Humans; Male; Microbial Sensitivity Tests; Middle Aged; Penicillanic Acid; Pneumonia, Ventilator-Associated; Pseudomonas aeruginosa; Pseudomonas Infections; Tazobactam | 2017 |
Successful treatment of multidrug-resistant
Topics: Cephalosporins; Cystectomy; Debridement; Drug Resistance, Multiple, Bacterial; Fistula; Humans; Male; Middle Aged; Osteomyelitis; Penicillanic Acid; Pseudomonas Infections; Pubic Symphysis; Tazobactam; Treatment Outcome | 2017 |
Clinical features and antimicrobial resistance profiles of important Enterobacteriaceae pathogens in Guangzhou representative of Southern China, 2001-2015.
Topics: Amikacin; Anti-Bacterial Agents; Blood; Carbapenems; Ceftazidime; Cephalosporins; China; Disk Diffusion Antimicrobial Tests; Drug Resistance, Bacterial; Enterobacter; Enterobacteriaceae; Escherichia coli; Humans; Klebsiella pneumoniae; Microbial Sensitivity Tests; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Sputum; Urinary Tract | 2017 |
Piperacillin-tazobactam versus cefepime incidence of acute kidney injury in combination with vancomycin and tobramycin in pediatric cystic fibrosis patients.
Topics: Acute Kidney Injury; Adolescent; Anti-Bacterial Agents; Cefepime; Cephalosporins; Child; Cystic Fibrosis; Drug Therapy, Combination; Female; Hospitalization; Humans; Incidence; Male; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Retrospective Studies; Tobramycin; Vancomycin | 2017 |
Cost-effectiveness of ceftolozane/tazobactam compared with piperacillin/tazobactam as empiric therapy based on the in-vitro surveillance of bacterial isolates in the United States for the treatment of complicated urinary tract infections.
Topics: Adult; Anti-Bacterial Agents; Cephalosporins; Cost-Benefit Analysis; Hospitalization; Humans; Middle Aged; Monte Carlo Method; Mortality; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Quality-Adjusted Life Years; United States; Urinary Tract Infections | 2017 |
Ceftolozane-Tazobactam Activity against Pseudomonas aeruginosa Clinical Isolates from U.S. Hospitals: Report from the PACTS Antimicrobial Surveillance Program, 2012 to 2015.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Cephalosporins; Drug Resistance, Multiple, Bacterial; Microbial Sensitivity Tests; Penicillanic Acid; Pseudomonas aeruginosa; Tazobactam; United States | 2017 |
Activity of ceftolozane/tazobactam against surveillance and 'problem' Enterobacteriaceae, Pseudomonas aeruginosa and non-fermenters from the British Isles.
Topics: Anti-Infective Agents; beta-Lactamase Inhibitors; Cephalosporins; Epidemiological Monitoring; Gram-Negative Bacteria; Gram-Negative Bacterial Infections; Humans; Microbial Sensitivity Tests; Penicillanic Acid; Polymerase Chain Reaction; Tazobactam; United Kingdom | 2017 |
Acute kidney injury risk associated with piperacillin/tazobactam compared with cefepime during vancomycin therapy in hospitalised patients: a cohort study stratified by baseline kidney function.
Topics: Acute Kidney Injury; Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; beta-Lactamase Inhibitors; Cefepime; Cephalosporins; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Retrospective Studies; Risk Assessment; Vancomycin; Young Adult | 2017 |
Cost-effectiveness of ceftolozane/tazobactam plus metronidazole compared with piperacillin/tazobactam as empiric therapy for the treatment of complicated intra-abdominal infections based on the in-vitro surveillance of bacterial isolates in the UK.
Topics: Anti-Bacterial Agents; Bacteriological Techniques; Cephalosporins; Clinical Protocols; Drug Combinations; Drug Therapy, Combination; Female; Gram-Negative Bacterial Infections; Humans; Intraabdominal Infections; Male; Metronidazole; Models, Econometric; Monte Carlo Method; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Quality-Adjusted Life Years; Tazobactam; United Kingdom | 2017 |
In vitro susceptibility and resistance phenotypes in contemporary Enterobacter isolates in a university hospital in Crete, Greece.
Topics: Aminoglycosides; Anti-Bacterial Agents; Bacterial Proteins; beta-Lactamases; beta-Lactams; Carbapenems; Cefepime; Cephalosporins; Child; Colistin; Drug Resistance, Multiple, Bacterial; Enterobacter; Enterobacteriaceae Infections; Greece; Hospitals, University; Humans; Microbial Sensitivity Tests; Minocycline; Penicillanic Acid; Phenotype; Piperacillin; Piperacillin, Tazobactam Drug Combination; Tigecycline | 2017 |
Successful treatment of post-surgical osteomyelitis caused by XDR Pseudomonas aeruginosa with ceftolozane/tazobactam monotherapy.
Topics: Anti-Bacterial Agents; beta-Lactamase Inhibitors; Cephalosporins; Drug Resistance, Multiple, Bacterial; Fractures, Bone; Humans; Male; Microbial Sensitivity Tests; Middle Aged; Osteomyelitis; Penicillanic Acid; Pseudomonas aeruginosa; Pseudomonas Infections; Tazobactam; Treatment Outcome | 2017 |
Topics: Amino Acid Sequence; Anti-Bacterial Agents; Azabicyclo Compounds; beta-Lactamase Inhibitors; beta-Lactamases; Ceftazidime; Cephalosporins; DNA Gyrase; Drug Combinations; Drug Resistance, Multiple, Bacterial; Humans; Microbial Sensitivity Tests; Penicillanic Acid; Porins; Pseudomonas aeruginosa; Tazobactam | 2017 |
Monotherapy of ceftazidime-avibactam and ceftolozane-tazobactam: two effective antimicrobial agents against multidrug-resistant organisms except for NDM-1 isolates.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Azabicyclo Compounds; beta-Lactamases; Ceftazidime; Cephalosporins; Drug Combinations; Penicillanic Acid; Tazobactam | 2017 |
Monotherapy of ceftazidime-avibactam and ceftolozane-tazobactam against multidrug-resistant organisms.
Topics: Azabicyclo Compounds; Ceftazidime; Cephalosporins; Drug Combinations; Penicillanic Acid; Tazobactam | 2017 |
Clinical characteristics and outcomes of Pseudomonas aeruginosa bacteremia in febrile neutropenic children and adolescents with the impact of antibiotic resistance: a retrospective study.
Topics: Adolescent; Amikacin; Aminoglycosides; Anti-Bacterial Agents; Bacteremia; Carbapenems; Cephalosporins; Child; Child, Preschool; Drug Resistance, Multiple, Bacterial; Female; Fever; Fluoroquinolones; Humans; Male; Meropenem; Neutropenia; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Pseudomonas aeruginosa; Pseudomonas Infections; Retrospective Studies; Thienamycins | 2017 |
Multicenter Evaluation of Ceftazidime-Avibactam and Ceftolozane-Tazobactam Inhibitory Activity against Meropenem-Nonsusceptible Pseudomonas aeruginosa from Blood, Respiratory Tract, and Wounds.
Topics: Anti-Bacterial Agents; Azabicyclo Compounds; beta-Lactamase Inhibitors; Catheter-Related Infections; Ceftazidime; Cephalosporins; Cross Infection; Drug Combinations; Humans; Meropenem; Microbial Sensitivity Tests; Penicillanic Acid; Pseudomonas aeruginosa; Pseudomonas Infections; Tazobactam; Thienamycins | 2017 |
Dosing antibiotics in neonates: review of the pharmacokinetic data.
Topics: Adult; Aminoglycosides; Anti-Bacterial Agents; beta-Lactams; Birth Weight; Body Size; Cephalosporins; Child; Clindamycin; Glycopeptides; Humans; Infant; Infant, Newborn; Medication Reconciliation; Meropenem; Metronidazole; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Thienamycins | 2017 |
Influence of β-Lactam Infusion Strategy on Acute Kidney Injury.
Topics: Acute Kidney Injury; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; beta-Lactamase Inhibitors; Cefepime; Cephalosporins; Drug Therapy, Combination; Female; Humans; Kidney; Male; Meropenem; Middle Aged; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Retrospective Studies; Thienamycins | 2017 |
Determination of Disk Diffusion and MIC Quality Control Guidelines for High-Dose Cefepime-Tazobactam (WCK 4282), a Novel Antibacterial Combination Consisting of a β-Lactamase Inhibitor and a Fourth-Generation Cephalosporin.
Topics: Anti-Bacterial Agents; beta-Lactamase Inhibitors; beta-Lactamases; Cefepime; Cephalosporins; Disk Diffusion Antimicrobial Tests; Drug Combinations; Gram-Negative Bacteria; Gram-Negative Bacterial Infections; Guidelines as Topic; Humans; Penicillanic Acid; Quality Control; Tazobactam | 2017 |
Does compliance with antibiotic prophylaxis in pediatric simple appendicitis matter?
Topics: Adolescent; Anti-Bacterial Agents; Antibiotic Prophylaxis; Appendectomy; Appendicitis; Cefepime; Cephalosporins; Child; Child, Preschool; Drug Therapy, Combination; Female; Follow-Up Studies; Guideline Adherence; Humans; Infant; Infant, Newborn; Logistic Models; Male; Metronidazole; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Practice Guidelines as Topic; Preoperative Care; Retrospective Studies; Surgical Wound Infection; Treatment Outcome | 2017 |
Topics: Anti-Bacterial Agents; Cefepime; Ceftazidime; Cephalosporins; Ciprofloxacin; Drug Combinations; Drug Resistance, Multiple, Bacterial; Febrile Neutropenia; Humans; Iatrogenic Disease; Meropenem; Microbial Sensitivity Tests; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Pneumonia; Practice Guidelines as Topic; Pseudomonas aeruginosa; Pseudomonas Infections; Sepsis; Tazobactam; Thienamycins; Tobramycin | 2017 |
Emergence of Ceftolozane-Tazobactam-Resistant Pseudomonas aeruginosa during Treatment Is Mediated by a Single AmpC Structural Mutation.
Topics: Aged; Anti-Bacterial Agents; Bacterial Proteins; beta-Lactamase Inhibitors; beta-Lactamases; Cephalosporins; Drug Resistance, Multiple, Bacterial; Humans; Male; Microbial Sensitivity Tests; Multilocus Sequence Typing; Penicillanic Acid; Polymorphism, Single Nucleotide; Pseudomonas aeruginosa; Pseudomonas Infections; Tazobactam; Wound Infection | 2017 |
Susceptibility of MDR Pseudomonas aeruginosa to ceftolozane/tazobactam and comparison of different susceptibility testing methods.
Topics: Anti-Bacterial Agents; Bacterial Proteins; Cephalosporins; Cytoskeletal Proteins; Drug Resistance, Multiple, Bacterial; Germany; Humans; Microbial Sensitivity Tests; Multilocus Sequence Typing; Penicillanic Acid; Pseudomonas aeruginosa; Pseudomonas Infections; Tazobactam | 2017 |
Successful treatment of three severe MDR or XDR Pseudomonas aeruginosa infections with ceftolozane/tazobactam.
Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; beta-Lactamase Inhibitors; Cephalosporins; Drug Resistance, Multiple, Bacterial; Drug Synergism; Female; Humans; Male; Penicillanic Acid; Pseudomonas aeruginosa; Pseudomonas Infections; Tazobactam; Treatment Outcome | 2017 |
Activity of Ceftolozane-Tazobactam and Ceftazidime-Avibactam against Beta-Lactam-Resistant Pseudomonas aeruginosa Isolates.
Topics: Anti-Bacterial Agents; Azabicyclo Compounds; beta-Lactam Resistance; beta-Lactamases; Cefepime; Ceftazidime; Cephalosporins; Drug Combinations; Gene Expression; Humans; Los Angeles; Meropenem; Microbial Sensitivity Tests; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Pseudomonas aeruginosa; Pseudomonas Infections; Tazobactam; Thienamycins | 2017 |
Ceftolozane-Tazobactam for the Treatment of Multidrug-Resistant Pseudomonas aeruginosa Infections: Clinical Effectiveness and Evolution of Resistance.
Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Cephalosporins; Drug Resistance, Multiple, Bacterial; Female; Genome, Bacterial; Humans; Male; Middle Aged; Penicillanic Acid; Pennsylvania; Pseudomonas aeruginosa; Pseudomonas Infections; Retrospective Studies; Tazobactam; Young Adult | 2017 |
Antimicrobial Activity of Ceftolozane-Tazobactam Tested Against Enterobacteriaceae and Pseudomonas aeruginosa with Various Resistance Patterns Isolated in U.S. Hospitals (2013-2016) as Part of the Surveillance Program: Program to Assess Ceftolozane-Tazoba
Topics: Amikacin; Anti-Bacterial Agents; Cephalosporins; Drug Resistance, Multiple, Bacterial; Enterobacteriaceae; Enterobacteriaceae Infections; Hospitals; Humans; Meropenem; Microbial Sensitivity Tests; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Pseudomonas aeruginosa; Pseudomonas Infections; Tazobactam; Thienamycins | 2018 |
Potential of high-dose cefepime/tazobactam against multiresistant Gram-negative pathogens.
Topics: Anti-Bacterial Agents; Bacterial Proteins; beta-Lactamase Inhibitors; beta-Lactamases; Cefepime; Cephalosporins; Drug Combinations; Drug Resistance, Multiple, Bacterial; Enterobacteriaceae; Enterobacteriaceae Infections; Humans; Microbial Sensitivity Tests; Penicillanic Acid; Tazobactam | 2018 |
Ceftolozane/tazobactam for the treatment of MDR Pseudomonas aeruginosa left ventricular assist device infection as a bridge to heart transplant.
Topics: Anti-Bacterial Agents; Cephalosporins; Drug Resistance, Multiple, Bacterial; Heart Transplantation; Heart-Assist Devices; Humans; Male; Middle Aged; Penicillanic Acid; Prosthesis-Related Infections; Pseudomonas aeruginosa; Pseudomonas Infections; Tazobactam | 2018 |
Determination of alternative ceftolozane/tazobactam dosing regimens for patients with infections due to Pseudomonas aeruginosa with MIC values between 4 and 32 mg/L.
Topics: Anti-Bacterial Agents; Cephalosporins; Cross Infection; Drug Combinations; Female; Humans; Infusions, Intravenous; Kidney Function Tests; Male; Microbial Sensitivity Tests; Monte Carlo Method; Penicillanic Acid; Pseudomonas aeruginosa; Pseudomonas Infections; Tazobactam | 2017 |
Ceftolozane/tazobactam in the treatment of osteomyelitis and skin and soft-tissue infections due to extensively drug-resistant Pseudomonas aeruginosa: clinical and microbiological outcomes.
Topics: Aged; Aged, 80 and over; Anti-Bacterial Agents; beta-Lactamase Inhibitors; Cephalosporins; Drug Resistance, Multiple, Bacterial; Female; Humans; Male; Middle Aged; Osteomyelitis; Penicillanic Acid; Pseudomonas aeruginosa; Pseudomonas Infections; Retrospective Studies; Skin Diseases, Bacterial; Soft Tissue Infections; Tazobactam; Treatment Outcome | 2018 |
Clinical efficacy and safety of cefepime-tazobactam in hospitalized patients in South India.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; beta-Lactamases; Cefepime; Cephalosporins; Escherichia coli; Escherichia coli Infections; Female; Hospitalization; Humans; India; Klebsiella Infections; Klebsiella pneumoniae; Male; Middle Aged; Penicillanic Acid; Piperacillin; Tazobactam; Treatment Outcome; Young Adult | 2018 |
Empiric antibiotic therapy in urinary tract infection in patients with risk factors for antibiotic resistance in a German emergency department.
Topics: Aged; Aged, 80 and over; Anti-Bacterial Agents; Area Under Curve; Cephalosporins; Ciprofloxacin; Drug Resistance, Multiple, Bacterial; Emergency Service, Hospital; Female; Fluoroquinolones; Gentamicins; Germany; Humans; Male; Middle Aged; Odds Ratio; Penicillanic Acid; Piperacillin; Risk Factors; ROC Curve; Tazobactam; Urinary Tract Infections | 2018 |
[Antimicrobial activity of ceftolozane/tazobactam against Enterobacteriaceae and Pseudomonas aeruginosa in the Czech Republic in 2016].
Topics: Anti-Infective Agents, Urinary; Cephalosporins; Czech Republic; Drug Resistance, Bacterial; Enterobacteriaceae; Humans; Microbial Sensitivity Tests; Penicillanic Acid; Pseudomonas aeruginosa; Tazobactam; Urinary Tract Infections | 2017 |
Ceftolozane-tazobactam therapy for multidrug-resistant Pseudomonas aeruginosa infections in patients with hematologic malignancies and hematopoietic-cell transplant recipients.
Topics: Adult; Aged; Anti-Bacterial Agents; Cephalosporins; Drug Resistance, Multiple, Bacterial; Female; Hematologic Neoplasms; Hematopoietic Stem Cell Transplantation; Humans; Male; Middle Aged; Oregon; Penicillanic Acid; Pseudomonas aeruginosa; Pseudomonas Infections; Tazobactam; Treatment Outcome | 2018 |
In vitro antimicrobial activity of ceftolozane/tazobactam against Pseudomonas aeruginosa and other non-fermenting Gram-negative bacteria in adults with cystic fibrosis.
Topics: Achromobacter denitrificans; Adult; beta-Lactamase Inhibitors; Burkholderia cenocepacia; Cephalosporins; Colistin; Cystic Fibrosis; Drug Resistance, Multiple, Bacterial; Gram-Negative Bacteria; Humans; Microbial Sensitivity Tests; Penicillanic Acid; Pseudomonas aeruginosa; Sputum; Stenotrophomonas maltophilia; Tazobactam | 2018 |
Which non-carbapenem antibiotics are active against extended-spectrum β-lactamase-producing Enterobacteriaceae?
Topics: Anti-Bacterial Agents; Azabicyclo Compounds; beta-Lactamases; Carbapenems; Ceftazidime; Cephalosporins; Drug Combinations; Enterobacteriaceae; Enterobacteriaceae Infections; Escherichia coli; Humans; Klebsiella pneumoniae; Microbial Sensitivity Tests; Penicillanic Acid; Tazobactam; Urinary Tract Infections | 2018 |
Ceftolozane/tazobactam for the treatment of XDR Pseudomonas aeruginosa infections.
Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Cephalosporins; Drug Resistance, Bacterial; Female; Follow-Up Studies; Humans; Infection Control; Male; Microbial Sensitivity Tests; Middle Aged; Penicillanic Acid; Pseudomonas aeruginosa; Pseudomonas Infections; Retrospective Studies; Tazobactam; Treatment Failure; Treatment Outcome; Young Adult | 2018 |
Bacteraemia due to extensively drug-resistant Pseudomonas aeruginosa sequence type 235 high-risk clone: Facing the perfect storm.
Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Azabicyclo Compounds; Bacteremia; Bacterial Proteins; Bacterial Toxins; Bacterial Typing Techniques; beta-Lactamases; Ceftazidime; Cephalosporins; Clone Cells; Drug Combinations; Drug Resistance, Multiple, Bacterial; Female; Gene Expression; Humans; Male; Middle Aged; Multivariate Analysis; Penicillanic Acid; Pseudomonas aeruginosa; Pseudomonas Infections; Respiratory Tract Infections; Retrospective Studies; Survival Analysis; Tazobactam | 2018 |
Validated HPLC-UV detection method for the simultaneous determination of ceftolozane and tazobactam in human plasma.
Topics: Anti-Bacterial Agents; Cephalosporins; Chromatography, High Pressure Liquid; Humans; Penicillanic Acid; Plasma; Tazobactam | 2018 |
Ceftolozane/tazobactam sensitivity patterns in Pseudomonas aeruginosa isolates recovered from sputum of cystic fibrosis patients.
Topics: Adult; Anti-Bacterial Agents; Cephalosporins; Cross Infection; Cystic Fibrosis; Drug Resistance, Multiple, Bacterial; Female; Humans; Male; Microbial Sensitivity Tests; Penicillanic Acid; Pseudomonas aeruginosa; Pseudomonas Infections; Sputum; Tazobactam | 2018 |
[Analysis of the distribution characteristics and drug resistance of non-fermenting bacterial infection in intensive care unit from 2009 to 2015]
Topics: Acinetobacter baumannii; Anti-Bacterial Agents; Bacterial Infections; Cefepime; Cefoperazone; Cephalosporins; Cross Infection; Drug Resistance; Drug Resistance, Bacterial; Gram-Negative Bacteria; Humans; Imipenem; Intensive Care Units; Meropenem; Microbial Sensitivity Tests; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Pseudomonas aeruginosa; Retrospective Studies; Thienamycins | 2016 |
Ceftolozane/Tazobactam vs Polymyxin or Aminoglycoside-based Regimens for the Treatment of Drug-resistant Pseudomonas aeruginosa.
Topics: Aminoglycosides; Anti-Bacterial Agents; Cephalosporins; Drug Resistance, Multiple, Bacterial; Humans; Microbial Sensitivity Tests; Penicillanic Acid; Pharmaceutical Preparations; Polymyxins; Pseudomonas aeruginosa; Pseudomonas Infections; Retrospective Studies; Tazobactam | 2020 |
Piperacillin-tazobactam should be preferred to third-generation cephalosporins to treat wild-type inducible AmpC-producing Enterobacterales in critically ill patients with hospital or ventilator-acquired pneumonia.
Topics: Aged; Anti-Bacterial Agents; Bacterial Proteins; beta-Lactamases; Cephalosporins; Critical Illness; Cross Infection; Enterobacter; Family Characteristics; Female; Hospitals; Humans; Male; Middle Aged; Neoplasm Recurrence, Local; Penicillanic Acid; Piperacillin, Tazobactam Drug Combination; Pneumonia, Ventilator-Associated; Retrospective Studies; Ventilators, Mechanical | 2020 |
Low pH reduces the activity of ceftolozane/tazobactam in human urine, but confirms current breakpoints for urinary tract infections.
Topics: Anti-Bacterial Agents; Cephalosporins; Humans; Hydrogen-Ion Concentration; Microbial Sensitivity Tests; Penicillanic Acid; Pseudomonas aeruginosa; Tazobactam; Urinary Tract Infections | 2020 |
[New possibilities in antibacterial treatment of intra-abdominal infections caused by multiresistant microflora].
Topics: Anti-Bacterial Agents; Azabicyclo Compounds; Ceftazidime; Cephalosporins; Drug Combinations; Drug Resistance, Multiple, Bacterial; Humans; Intraabdominal Infections; Penicillanic Acid | 2019 |
Susceptibility trends of ceftolozane/tazobactam and comparators when tested against European Gram-negative bacterial surveillance isolates collected during 2012-18.
Topics: Anti-Bacterial Agents; Cephalosporins; Cross Infection; Drug Resistance, Multiple, Bacterial; Europe; Europe, Eastern; Gram-Negative Bacteria; Humans; Microbial Sensitivity Tests; Penicillanic Acid; Pseudomonas aeruginosa; Pseudomonas Infections; Tazobactam | 2020 |
Continuous infusion of ceftolozane-tazobactam resulted in high cerebrospinal fluid concentrations of ceftolozane in a patient with multidrug-resistant Pseudomonas aeruginosa meningitis.
Topics: Anti-Bacterial Agents; Cephalosporins; Drug Resistance, Multiple, Bacterial; Humans; Meningitis; Microbial Sensitivity Tests; Penicillanic Acid; Pseudomonas aeruginosa; Pseudomonas Infections; Tazobactam | 2021 |
What place does ceftolozane/tazobactam have in the treatment of complicated urinary-tract infections?
Topics: Anti-Bacterial Agents; Cephalosporins; Drug Resistance, Multiple, Bacterial; Humans; Microbial Sensitivity Tests; Penicillanic Acid; Pseudomonas aeruginosa; Pseudomonas Infections; Tazobactam; Urinary Tract Infections | 2021 |
Plasma and soft tissue pharmacokinetics of ceftolozane/tazobactam in healthy volunteers after single and multiple intravenous infusion: a microdialysis study.
Topics: Anti-Bacterial Agents; Cephalosporins; Healthy Volunteers; Humans; Infusions, Intravenous; Microbial Sensitivity Tests; Microdialysis; Penicillanic Acid; Prospective Studies; Pseudomonas aeruginosa; Tazobactam | 2021 |
Ceftolozane/tazobactam for refractory P. aeruginosa endocarditis: A case report and pharmacokinetic analysis.
Topics: Anti-Bacterial Agents; Cephalosporins; Endocarditis; Humans; Male; Microbial Sensitivity Tests; Middle Aged; Penicillanic Acid; Pseudomonas aeruginosa; Pseudomonas Infections; Tazobactam | 2022 |
Activity of Ceftolozane-Tazobactam Against Gram-Negative Isolates from Australia and New Zealand as part of the PACTS Surveillance 2016-2018.
Topics: Anti-Bacterial Agents; beta-Lactamase Inhibitors; Cephalosporins; Drug Resistance, Multiple, Bacterial; Enterobacteriaceae; Meropenem; Microbial Sensitivity Tests; New Zealand; Penicillanic Acid; Piperacillin, Tazobactam Drug Combination; Pseudomonas aeruginosa; Tazobactam | 2022 |
Definitive antibiotic treatment with a third-generation cephalosporin and with piperacillin-tazobactam worked well for some children with Serratia bacteraemia.
Topics: Aged; Anti-Bacterial Agents; Bacteremia; Cephalosporins; Child; Female; Humans; Male; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Serratia; Thrombocytopenia | 2022 |
In vitro activity of ceftolozane/tazobactam against multidrug-resistant Pseudomonas aeruginosa from patients in Western Europe: SMART 2017-2020.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; beta-Lactamases; Ceftazidime; Cephalosporins; Drug Resistance, Multiple, Bacterial; Humans; Microbial Sensitivity Tests; Penicillanic Acid; Pseudomonas aeruginosa; Pseudomonas Infections; Tazobactam | 2023 |
Susceptibility of ceftolozane/tazobactam against multidrug-resistant and carbapenem-resistant Pseudomonas aeruginosa.
Topics: Anti-Bacterial Agents; Carbapenems; Cephalosporins; Drug Resistance, Multiple, Bacterial; Humans; Microbial Sensitivity Tests; Penicillanic Acid; Pseudomonas aeruginosa; Pseudomonas Infections; Tazobactam | 2023 |
Efficacy and safety of tazobactam/ceftolozane in combination with metronidazole for intraabdominal infection in a hepato-biliary-pancreatic field in clinical practice.
Topics: Anti-Bacterial Agents; Cephalosporins; Humans; Intraabdominal Infections; Metronidazole; Penicillanic Acid; Tazobactam | 2023 |
Early treatment response to piperacillin/tazobactam in patients with bloodstream infections caused by non-ESBL ampicillin/sulbactam-resistant Escherichia coli: a binational cohort study.
Topics: Adult; Ampicillin; Anti-Bacterial Agents; Bacteremia; Cephalosporins; Cohort Studies; Escherichia coli; Escherichia coli Infections; Humans; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Quinolones; Retrospective Studies; Sulbactam | 2023 |