cephalosporin c has been researched along with nitrocefin in 175 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 29 (16.57) | 18.7374 |
| 1990's | 34 (19.43) | 18.2507 |
| 2000's | 57 (32.57) | 29.6817 |
| 2010's | 48 (27.43) | 24.3611 |
| 2020's | 7 (4.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bourgault, AM; Rosenblatt, JE | 1 |
| Thornewell, SJ; Waley, SG | 1 |
| Jacoby, GA; Medeiros, AA; Papanicolaou, GA | 1 |
| Carles, MJ; Carrière, C; Jourdan, J; Ramuz, M; Sotto, A | 1 |
| Medeiros, AA; Papanicolaou, GA | 1 |
| Vaara, M | 1 |
| Christensen, H; Martin, MT; Waley, SG | 1 |
| Keiding, J; Mansa, B; Togsverd, E | 1 |
| Appelbaum, PC; Jacobs, MR; Spangler, SK | 1 |
| Kaiser, AB; Kernodle, DS; McGraw, PA; Stratton, CW | 1 |
| Stübner, G | 1 |
| Eliasson, I; Kamme, C; Miörner, H; Petersson, AC | 1 |
| Mavrommati, L; Tzelepi, E | 1 |
| Burnett, D; Dragicevic, P; Hill, SL; Merrikin, D; Stockley, RA | 1 |
| Garver, CG; Kellogg, JA | 1 |
| Hancock, RE; Moore, LV; Moore, RA; Parr, TR | 1 |
| Crompton, IE; Cuthbert, BK; Lowe, G; Waley, SG | 1 |
| Eley, A; Greenwood, D | 1 |
| Jimenez-Valera, M; Ramos-Cormenzana, A; Ruiz-Bravo, A | 1 |
| Bush, K | 1 |
| Goering, RV; McCloskey, RV; Sanders, CC; Sanders, WE | 1 |
| Amyes, SG; Harper, PB; Reid, AJ; Simpson, IN | 1 |
| Barry, AL; Jones, RN | 1 |
| Kellogg, JA | 1 |
| Cox, HU; Foil, CS; Hoskins, JD; Newman, SS; Roy, AF | 1 |
| Lyng, RV; Maeland, JA; Svarva, PL | 1 |
| Uri, JV | 1 |
| Yamabe, S | 1 |
| Barlam, T; Neu, HC | 1 |
| James, R | 1 |
| Lee, DT; Rosenblatt, JE | 1 |
| Chen, KC; Holmes, KK; Knapp, JS | 1 |
| de Silva, MI; Flournoy, DJ; Perryman, F; Qadri, SM | 1 |
| Hancock, RE; Wong, PG | 1 |
| Auger, F; Lacroix, JM; Lamothe, F | 1 |
| Jones, RN; Novick, WJ; Wilson, HW | 1 |
| Baselski, VS; Horton, KA; Jennings, BR | 1 |
| Barry, AL; Jones, RN; Novick, WJ; Thornsberry, C; Wilson, HW | 1 |
| Chen, HY; Livermore, DM; Yuan, M | 1 |
| Brunschwig, C; Carrière, C; Galtier, M; Geny, F; Jourdan, J; Peray, P; Ramuz, M; Sotto, A | 1 |
| Biedenbach, DJ; Jones, RN; Sutton, LD; Yen, A | 1 |
| Escobar, WA; Fink, AL; Miller, J | 1 |
| Nerli, B; Picó, G | 1 |
| Denny, BJ; Lambert, PA; Toomer, CA | 1 |
| Frère, JM; Ledent, P | 1 |
| Bush, K; Lee, VJ; Macalintal, C; Rasmussen, BA; Yang, Y | 1 |
| García, F; Nerli, B; Picó, G | 1 |
| Chen, CC; Coulson, A; Herzberg, O; Kapadia, G; Smith, TJ; Wäsch, S; Zawadzke, LE | 1 |
| Brems, DN; Kaiser, RE; Roychoudhury, S; Yeh, WK | 1 |
| Banerjee, S; Chen, CC; Herzberg, O; Kapadia, G; Li, Z; Moult, J; Wäsch, S; Zawadzke, LE | 1 |
| König, H; Martin, HH | 1 |
| Aguilar-Zacarías, C; Silva-Sánchez, J | 1 |
| Barendregt, D; Dellemijn-Kippuw, N; Stijne, A; van der Velden, U; van Winkelhoff, AJ; Winkel, EG | 1 |
| Botha, PL; Chalkley, LJ; Ison, CA; Janse van Rensburg, MN; Matthee, PC | 1 |
| Graves-Woodward, K; Pratt, RF | 2 |
| Benkovic, SJ; Wang, Z | 1 |
| Crowder, MW; McManus-Munoz, S | 1 |
| Firstenberg-Eden, R; Meszaros, AT; Strenkoski, LF | 1 |
| Adolph, HW; Bauer, R; de Seny, D; Frère, JM; Galleni, M; Hernandez-Valladares, M; Meyer-Klaucke, W; Nolting, H; Paul-Soto, R; Rossolini, GM; Zeppezauer, M | 1 |
| Ravaoarinoro, M; Therrien, C | 1 |
| Benkovic, SJ; Fast, W; Wang, Z | 2 |
| Adolph, HW; Bauer, R; Carfi, A; Dideberg, O; Frere, JM; Galleni, M; Hemmingsen, L; Paul-Soto, R; Wouters, J; Zeppezauer, M | 1 |
| Summanen, PH | 1 |
| McIntosh, TJ; Snyder, DS | 1 |
| Barredo, JL; Díez, B; Fouces, R; Velasco, J | 1 |
| Blais, J; Chamberland, S; Cho, D; Fronko, R; Galazzo, J; Hecker, S; Hoshino, K; Ishida, H; Lee, A; Lee, M; Lee, VJ; Leger, R; Lomovskaya, O; Renau, T; Warren, MS; Watkins, W | 1 |
| Anderson, JC; Magliery, TJ; Schultz, PG | 1 |
| Deriu, A; Fadda, G; Romano, L; Sechi, LA; Spanu, T; Zanetti, S | 1 |
| Bebrone, C; Docquier, JD; Fastrez, J; Frère, JM; Galleni, M; Mahy, F; Moali, C; Pratt, RF; Rival, S; Rossolini, GM | 1 |
| Kaminskaia, NV; Lippard, SJ; Spingler, B | 1 |
| Clarke, AR; Spencer, J; Walsh, TR | 1 |
| Eriksson, M; Good, L; Nielsen, PE | 1 |
| Brown, RS; Montoya-Pelaez, PJ | 1 |
| Carenbauer, AL; Crowder, MW; Garrity, JD; Periyannan, G; Yates, RB | 1 |
| Galarneau, A; Michnick, SW; Primeau, M; Trudeau, LE | 1 |
| Corrente, M; Greco, G; Madio, A; Ventriglia, G | 1 |
| Clarke, AJ; Dmitrienko, GI; Siemann, S; Viswanatha, T | 1 |
| Anne, C; Devreese, B; Frère, JM; Galleni, M; Groslambert, S; Lamotte-Brasseur, J; Moali, C; Van Beeumen, J | 1 |
| Benkovic, SJ; Dyson, HJ; Fast, W; Huntley, JJ; Wright, PE | 1 |
| Ceolín, M; Rasia, RM; Vila, AJ | 1 |
| Cavallo, JD; Hernandez, E; Ramisse, F | 1 |
| Brown, RS; Gibson, GT; Montoya-Pelaez, PJ; Neverov, AA | 1 |
| Guntas, G; Ostermeier, M | 1 |
| Baurin, SL; Bauvois, C; Colombo, ML; De Vriendt, K; Frère, JM; Hanique, S; Joris, B; Van Beeumen, JJ | 1 |
| Feijen, M; Gros, P; Oomen, CJ; Tommassen, J; van Gelder, P; van Ulsen, P | 1 |
| Hanaki, H; Kubo, R; Kurihara, M; Nakano, T; Sunagawa, K | 1 |
| Bethel, CR; Bonomo, RA; Helfand, MS; Hujer, AM | 1 |
| Avison, MB; Underwood, S | 1 |
| Chen, RR; Ni, Y | 1 |
| Hesek, D; Lee, M; Mobashery, S | 1 |
| Flores, AR; Parsons, LM; Pavelka, MS | 1 |
| Fuda, C; Hesek, D; Lee, M; Mobashery, S; Morio, K; Nowak, T | 1 |
| Haveri, M; Honkanen-Buzalski, T; Pyörälä, S; Rantala, L; Suominen, S | 1 |
| Brothers, EN; Merz, KM; Park, H | 1 |
| Arakawa, Y; Goto, M; Higashi, T; Jin, W; Kawanami, A; Kuroki, T; Kurosaki, H; Yamagata, Y; Yamaguchi, Y; Yasuzawa, H | 1 |
| Arndt, C; Reifferscheid, G; Schmid, C | 1 |
| Buckner, FS; Wilson, AJ | 1 |
| Bouillenne, F; Charlier, P; Duez, C; Frère, JM; Herman, R; Petrella, S; Sauvage, E | 1 |
| Arora, S; Bal, M | 1 |
| Aehle, W; Chin, R; Faravashi, N; Graycar, T; Harding, FA; Liu, AD; Meijer, D; Rashid, MH; Razo, OJ; Schellenberger, V; Stickler, M; Valdes, AM; Viola, W; Wong, S; Yeung, VP | 1 |
| Kim, JR; Ostermeier, M | 1 |
| Ghosh, I; Ooi, AT; Segal, DJ; Stains, CI | 1 |
| Sun, QY; Wang, BC; Yang, XS; Yang, ZC | 1 |
| Kumarasinghe, G; Kurupati, P; Poh, CL; Tan, KS | 1 |
| Beckstead, BL; Carmen, JC; Nelson, JL; Pitt, WG; Robison, RA; Runyan, CM | 1 |
| Bredbacka, P; Koskinen, MT; Myllyniemi, AL; Pitkälä, A; Salmikivi, L | 1 |
| Ghosh, I; Porter, JR; Segal, DJ; Stains, CI | 1 |
| Dideberg, O; Garau, G; Hernandez, JF; Kahn, R; Nauton, L | 1 |
| Dixon, RA; Sahalan, AZ | 1 |
| Atsuda, K; Hanaki, H; Koide, Y; Kubo, R; Nakano, T; Sunakawa, K; Yamazaki, H | 1 |
| Chin, YP; Hou, WC; Lee, MH; Lin, RD | 1 |
| Bennett, B; Crowder, MW; Hu, Z; Periyannan, G | 1 |
| Chiang, KH; Hu, RM; Lin, CW; Yang, TC | 1 |
| Brady, D; Magomani, V; Rashamuse, K; Ronneburg, T | 1 |
| Bethel, CR; Bonomo, RA; Distler, AM; Hujer, AM; Leonard, DA; Schneider, KD | 1 |
| Black, MT; Claudon, M; Girard, AM; Levasseur, P; Miossec, C; Péchereau, MC; Stachyra, T | 1 |
| Doble, M; Hemaiswarya, S | 1 |
| Begtrup, M; Hansen, HS; Pedersen, AH; Petersen, G; Pickering, DS | 1 |
| Chen, C; Nikaido, H; Takatsuka, Y | 1 |
| Blanchard, JS; Fan, F; Tremblay, LW | 1 |
| Biró, S; Buzás, K; Csorba, A; Gál, Z; Hulvely, J; Hunyadi-Gulyás, E; Jánosi, S; Kaszanyitzky, E; Keseru, JS; Massidda, O; Medzihradszky, KF; Mingoia, M; Szabó, I | 1 |
| Allemann, RK; Baldwin, AJ; Edwards, WR; Jones, DD; Morris, JL; Williams, AJ | 1 |
| Bebrone, C; Docquier, JD; Favier, A; Ferrer, JL; Frère, JM; Galleni, M; Lassaux, P; Laurent, C; Loisel, E; Sohier, JS; Traoré, DA | 1 |
| Eze, D; Kundzina, R; Mindere, A; Nikolajeva, V; Petrina, Z | 1 |
| Calas, P; Jabri, M; Rochd, T; Roques, C | 1 |
| Hirao, H; Morokuma, K; My, NH; Van, DU | 1 |
| Bruner, B; Farmer, PJ; Kim, SK; Schlesinger, SR | 1 |
| Dai, X; Gao, Q; Li, J; Xiang, S; Yang, K | 1 |
| Aitha, M; Crowder, MW; Hetrick, AM; Richmond, TK; Tierney, DL; Yang, H | 1 |
| Bethel, CR; Bonomo, RA; Buynak, JD; Carey, PR; Che, T; Pusztai-Carey, M; Shanmugam, S | 1 |
| Conklin, BC; Hutton, RA; Li, M; Skalweit, MJ; Taracila, MA | 1 |
| Chen, Y; Jiang, H; Jin, L; Kong, X; Li, JQ; Liang, Z; Lu, J; Luo, C; Ye, F; Yu, K; Zhu, K | 1 |
| Blanchard, JS; Chow, C; Xu, H | 1 |
| Goessens, WH; Melles, DC; Pitout, JD; Tommassen, J; van Boxtel, R; van der Bij, AK; van Ulsen, P | 1 |
| Faheem, M; Khan, AU; Rehman, MT | 1 |
| Kinana, AD; Nikaido, H; Vargiu, AV | 2 |
| Correa Signoretti, FG; Gomes, BP; Grecca, FS; Jacinto, RC; Montagner, F; Scheffer de Mattos, V | 1 |
| Demolli, S; Geist, MM; Matschiavelli, N; Rother, M; Suess, B; Weigand, JE | 1 |
| Betelli, L; Hartmann, A; Neuwirth, C; Rochelet, M; Solanas, S; Vienney, F | 1 |
| Huang, PJ; Labbé, G; Liu, J; Pautler, R; Shanmugaraj, J | 1 |
| Arakawa, Y; Kawamura, K; Mura, T; Shibayama, K; Wachino, J | 1 |
| Brem, J; Dmitrienko, GI; Ghavami, A; Goodfellow, VJ; King, DT; Labbé, G; Lam, M; Marrone, L; Pillai, DR; Schofield, CJ; Siemann, S; Spencer, J; Strynadka, NC; Tanner, CA | 1 |
| Kinana, AD; Misra, R; Morrison, KD; Nikaido, H; Soparkar, K; Weeks, JW | 1 |
| Kujawa, M; Majewski, S; Malejczyk, M; Mlynarczyk, G; Mlynarczyk-Bonikowska, B | 1 |
| Bohnert, JA; Handzlik, J; Kaczor, A; Karcz, T; Kern, WV; Kieć-Kononowicz, K; Olejarz, A; Schuster, S | 1 |
| Borić Vezjak, M; Danevčič, T; Stopar, D; Zorec, M | 1 |
| Craig, WR; Guddat, LW; Harmer, J; Helweh, W; Larrabee, JA; Mitić, N; Monteiro Pedroso, M; Ollis, DL; Schenk, G; Selleck, C; Tierney, DL | 1 |
| Allam, A; Alves de Sousa, R; Artaud, I; Dumont, E; Maigre, L; Pagès, JM; Vergalli, J | 1 |
| Breukink, E; Calvez, P; Contreras-Martel, C; Dib, M; Roper, DI; Zapun, A | 1 |
| Arthur, M; Ourghanlian, C; Soroka, D | 1 |
| Bell, DT; Chauhan, V; Kaushik, A; Kumar, P; Lamichhane, G; Stevens, RL; Xia, F | 1 |
| Bilyj, J; Gahan, LR; Harmer, JR; Larrabee, JA; Mitić, N; Monteiro Pedroso, M; Schenk, G; Selleck, C; Standish, AJ; Tierney, DL | 1 |
| Arthur, M; Edoo, Z; Hugonnet, JE | 1 |
| Keller, PM; Müller, DM; Rominski, A; Sander, P; Schulthess, B | 1 |
| Eumkeb, G; Evans, K; Hobbs, G; Nakouti, I; Teethaisong, Y | 2 |
| Barbuddhe, SB; Kumar, M; Malik, SVS; Pathak, R; Rawool, DB; Sunitha, R; Vergis, J | 1 |
| Boehle, KE; Caraway, J; Carrell, CS; Henry, CS | 1 |
| Adams-Sapper, S; deBoer, TR; DePaola, P; Maity, S; Murthy, N; Riley, LW; Sadlowski, CM; Tarlton, NJ; Vesgesna, GK; Wu, TZ; Yamaji, R | 1 |
| Cha, SS; Chung, KM; Jeong, BG; Kim, MK; Lee, TH; Na, JH; Park, SB | 1 |
| Sharma, AK; Vats, P | 1 |
| Deng, X; Gao, Y; Niu, X; Sun, L; Wang, G; Wang, X; Yang, Y; Yu, Y | 1 |
| Ghosh, AS; Ghosh, SK; Kumar N, G; Kumar, G; Mallick, S; Pramanick, P | 1 |
| Andreasen, MR; Hansen, KH; Jelsbak, L; Pedersen, MS; Schønning, K; Westh, H | 1 |
| Blanchet, M; Bourguet-Kondracki, ML; Brunel, JM; Cadelis, MM; Copp, BR; Kang, W; Pike, EIW; Vidal, N; Wu, Z | 1 |
| Cox, JAG; Desai, M; Harrison, J; Lambert, PA; Lopeman, RC; Rathbone, DL | 1 |
| Allen, C; Jamieson, D; Kalsi, S; Li, Y; Morgan, H; Sutton, JM; Turner, C | 1 |
| Yuk, HG; Zwe, YH | 1 |
| Adekanle, O; Adeleye, IA; Agbo, I; Ally, R; Carranza, M; Clarke, A; Fischer, W; Haas, R; Harrison, U; Idowu, A; Jolaiya, T; Lesi, O; Loell, E; Ndububa, D; Njom, H; Onyekwere, C; Palamides, P; Smith, S; Ugiagbe, R | 1 |
| Aubry, B; Chenouard, R; Eveillard, M; Kempf, M; Lemarié, C; Pailhoriès, H | 1 |
| Ahmadvand, P; Avillan, JJ; Call, DR; Kang, C; Lewis, JA | 1 |
| Bradley, J; Huynh, HK; Maher, JM; Mendes, RE; Porsch, EA; St Geme Iii, JW; Yagupsky, P | 1 |
175 other study(ies) available for cephalosporin c and nitrocefin
| Article | Year |
|---|---|
Characterization of anaerobic gram-negative bacilli by using rapid slide tests for beta-lactamase production.
Topics: Bacteriological Techniques; Bacteroides; Bacteroides fragilis; beta-Lactamases; Cephalosporins; Fusobacterium; Gram-Negative Anaerobic Bacteria; Penicillin Resistance; Prevotella melaninogenica | 1979 |
Site-directed mutagenesis and substrate-induced inactivation of beta-lactamase I.
Topics: Cephalosporins; Cloxacillin; Drug Stability; Enzyme Activation; Hydrolysis; Kinetics; Mutagenesis, Site-Directed; Penicillin G; Penicillinase | 1992 |
Novel plasmid-mediated beta-lactamase (MIR-1) conferring resistance to oxyimino- and alpha-methoxy beta-lactams in clinical isolates of Klebsiella pneumoniae.
Topics: Anti-Bacterial Agents; Base Sequence; beta-Lactamases; Cephalosporinase; Cephalosporins; Cloning, Molecular; DNA Restriction Enzymes; DNA, Bacterial; Drug Resistance, Microbial; Enzyme Induction; Humans; Isoelectric Focusing; Klebsiella Infections; Klebsiella pneumoniae; Microbial Sensitivity Tests; Molecular Sequence Data; Plasmids | 1990 |
[Kinetics of serum activity of beta-lactamases inhibitors. Development of a biologic assay].
Topics: beta-Lactamases; Cephalosporins; Clavulanic Acids; Humans; Indicators and Reagents; Sulbactam | 1991 |
Discrimination of extended-spectrum beta-lactamases by a novel nitrocefin competition assay.
Topics: beta-Lactamases; Binding, Competitive; Cephalosporins; Chromosomes, Bacterial; Hydrolysis; Isoelectric Focusing | 1990 |
The effect of oligolysines Lys-3, Lys-4, and Lys-5 on the outer membrane permeability of Pseudomonas aeruginosa.
Topics: 1-Naphthylamine; Cell Membrane Permeability; Cephalosporins; Fluorescent Dyes; Lipopolysaccharides; Osmolar Concentration; Polyamines; Polyelectrolytes; Polylysine; Polymers; Pseudomonas aeruginosa; Rifampin | 1990 |
Beta-lactamases as fully efficient enzymes. Determination of all the rate constants in the acyl-enzyme mechanism.
Topics: Acylation; Bacillus cereus; beta-Lactamase Inhibitors; beta-Lactamases; Cephalosporins; Chemical Phenomena; Chemistry; Deuterium; Escherichia coli; Hydrolysis; Kinetics; Penicillanic Acid; Penicillin G; Staphylococcus aureus; Substrate Specificity | 1990 |
Studies on beta-lactamases from Escherichia coli isolated from urinary tract infections.
Topics: Anti-Bacterial Agents; beta-Lactamases; Cephalosporins; Denmark; Drug Resistance, Microbial; Escherichia coli; Humans; Isoelectric Focusing; Substrate Specificity; Urinary Tract Infections | 1990 |
Evaluation of two methods for rapid testing for beta-lactamase production in Bacteroides and Fusobacterium.
Topics: Amoxicillin; Bacteroides; beta-Lactamases; Cephalosporins; Fusobacterium; Indicators and Reagents; Microbial Sensitivity Tests | 1990 |
Use of extracts versus whole-cell bacterial suspensions in the identification of Staphylococcus aureus beta-lactamase variants.
Topics: beta-Lactamases; Cell-Free System; Cells, Cultured; Cephalosporins; Genetic Variation; Hydrolysis; Isoenzymes; Methods; Staphylococcus aureus; Substrate Specificity; Suspensions | 1990 |
Indirect evidence of cell wall alterations in pseudomonas aeruginosa by immunoglobulin preparations.
Topics: beta-Lactamases; Cell Wall; Cephalosporins; gamma-Globulins; Humans; Immunoglobulin G; Immunoglobulins, Intravenous; Indicators and Reagents; Pseudomonas aeruginosa | 1985 |
Evaluation of four qualitative methods for detection of beta-lactamase production in Staphylococcus and Micrococcus species.
Topics: Bacteriological Techniques; beta-Lactamases; Cephalosporins; False Negative Reactions; False Positive Reactions; Humans; Microbial Sensitivity Tests; Micrococcus; Penicillin G; Staphylococcus; Staphylococcus aureus | 1989 |
Conjugal transfer of penicillin resistance plasmids to proline-citrulline-uracil dependent strains of Neisseria gonorrhoeae.
Topics: beta-Lactamases; Cephalosporins; Citrulline; Conjugation, Genetic; Culture Media; Microbial Sensitivity Tests; Neisseria gonorrhoeae; Penicillin G; Penicillin Resistance; Plasmids; Proline; Spectinomycin; Uracil | 1989 |
Activities and sources of beta-lactamase in sputum from patients with bronchiectasis.
Topics: Albumins; Bacteroides fragilis; beta-Lactamases; Bronchiectasis; Cephalosporins; Chromatography, High Pressure Liquid; Colorimetry; Escherichia coli; Haemophilus influenzae; Humans; Indicators and Reagents; Proteus; Saliva; Sputum; Staphylococcus aureus | 1989 |
Improved detection of beta-lactamase activity in isolates of Staphylococcus saprophyticus with the use of a modified Cefinase disk procedure.
Topics: beta-Lactamases; Cephalosporins; Clinical Enzyme Tests; Forecasting; Humans; Penicillin Resistance; Staphylococcus | 1989 |
Role of porins in intrinsic antibiotic resistance of Pseudomonas cepacia.
Topics: Anti-Bacterial Agents; Bacterial Outer Membrane Proteins; Cell Membrane; Cell Membrane Permeability; Cephalosporins; Drug Resistance, Microbial; Electrophoresis, Polyacrylamide Gel; Porins; Pseudomonas | 1987 |
Beta-lactamase inhibitors. The inhibition of serine beta-lactamases by specific boronic acids.
Topics: Bacillus cereus; beta-Lactamase Inhibitors; Binding Sites; Boronic Acids; Cephalosporins; Hydrogen-Ion Concentration; Isoenzymes; Kinetics; Models, Chemical; Protein Binding; Thermodynamics | 1988 |
Beta-lactamases of type culture strains of the Bacteroides fragilis group and of strains that hydrolyse cefoxitin, latamoxef and imipenem.
Topics: Bacteroides fragilis; beta-Lactamase Inhibitors; beta-Lactamases; Cefoxitin; Cephalosporins; Drug Resistance, Microbial; Imipenem; Isoelectric Point; Kinetics; Microbial Sensitivity Tests; Moxalactam; Nephelometry and Turbidimetry; Thienamycins | 1986 |
Synergistic effects of dicloxacillin or clavulanic acid in combination with penicillin G or cephalothin against Yersinia enterocolitica.
Topics: beta-Lactamase Inhibitors; Cephalosporins; Cephalothin; Clavulanic Acid; Clavulanic Acids; Dicloxacillin; Drug Synergism; Microbial Sensitivity Tests; Penicillin G; Yersinia enterocolitica | 1986 |
Evaluation of enzyme inhibition data in screening for new drugs.
Topics: Acetylcholinesterase; Acetylmuramyl-Alanyl-Isoglutamine; Animals; Benzene Derivatives; beta-Lactamase Inhibitors; Cephalosporins; Cholinesterase Inhibitors; Drug Evaluation; Enzyme Inhibitors; Kinetics; Lactones; Mathematics; Phenazines; Rabbits; Research Design | 1986 |
Leakage of beta-lactamase: a second mechanism for antibiotic potentiation by amdinocillin.
Topics: Amdinocillin; Animals; Anti-Bacterial Agents; Bacteria; beta-Lactamases; Cephalosporins; Drug Synergism; Enzyme Induction; Indicators and Reagents; Mice; Microbial Sensitivity Tests | 1987 |
Ampicillin resistance in Haemophilus influenzae: identification of resistance mechanisms.
Topics: Ampicillin; Ampicillin Resistance; Bacterial Outer Membrane Proteins; Bacterial Proteins; beta-Lactamases; Carrier Proteins; Cephalosporins; Haemophilus influenzae; Hexosyltransferases; Isoelectric Focusing; Microbial Sensitivity Tests; Muramoylpentapeptide Carboxypeptidase; Penicillin-Binding Proteins; Peptidyl Transferases | 1987 |
Beta-lactamase hydrolysis and inhibition studies of the new 1-carbacephem LY163892.
Topics: beta-Lactamase Inhibitors; beta-Lactamases; Cefaclor; Cefotaxime; Cephaloridine; Cephalosporins; Hydrolysis | 1987 |
Problems encountered in using Cefinase disks to predict in vitro penicillin susceptibility of coagulase-negative staphylococci.
Topics: Cephalosporins; Coagulase; Humans; Indicators and Reagents; Microbial Sensitivity Tests; Penicillins; Staphylococcus | 1987 |
Detection of beta-lactamase produced by Staphylococcus intermedius.
Topics: Animals; beta-Lactamases; Bromcresol Purple; Cephalosporins; Dogs; Indicators and Reagents; Iodine; Reagent Strips; Staphylococcus | 1985 |
Emergence of beta-lactam multiresistant variants of gram-negative bacilli in the presence of cefotaxime.
Topics: beta-Lactamases; Cefotaxime; Cephalosporins; Drug Resistance, Microbial; Enterobacter; Enterobacteriaceae; Escherichia coli; Humans; Klebsiella; Pseudomonas | 1985 |
Detection of beta-lactamase activity with nitrocefin of multiple strains of various microbial genera.
Topics: Bacteria; beta-Lactamases; Cephalosporins; Enterobacter; Enterococcus faecalis; Escherichia coli; Haemophilus influenzae; Indicators and Reagents; Klebsiella pneumoniae; Neisseria gonorrhoeae; Proteus; Pseudomonas aeruginosa; Serratia marcescens; Species Specificity | 1985 |
Spectrophotometric determination of inhibitory effects of CP-45899 on beta-lactamase with benzylpenicillin and nitrocefin.
Topics: Bacillus cereus; beta-Lactamase Inhibitors; beta-Lactamases; Cephalosporins; Cytochrome c Group; Hydrolysis; Oxidation-Reduction; Penicillanic Acid; Penicillin G; Spectrophotometry; Sulbactam | 1980 |
Pyridinium 2-azo-p-dimethylaniline chromophore, a chromogenic reagent for beta-lactamase testing compared to nitrocefin.
Topics: Anti-Bacterial Agents; Bacteria; beta-Lactamase Inhibitors; beta-Lactamases; Cephaloridine; Cephalosporins; Chromogenic Compounds; Drug Resistance, Microbial; Indicators and Reagents; Spectrophotometry | 1984 |
Relative substrate affinity index values: a method for identification of beta-lactamase enzymes and prediction of successful beta-lactam therapy.
Topics: Anti-Bacterial Agents; beta-Lactamases; Cefoxitin; Cephalosporins; Enterobacter; Escherichia coli; Klebsiella pneumoniae; Microbial Sensitivity Tests; Substrate Specificity | 1983 |
A comparison of four methods for detecting beta-lactamase in anaerobic bacteria.
Topics: Bacteria, Anaerobic; Bacteriological Techniques; Bacteroides; beta-Lactamases; Bromcresol Purple; Cephalosporins; Chromogenic Compounds; Clostridium; Fusobacterium; Indicators and Reagents; Penicillin G | 1983 |
Rapid, inexpensive method for specific detection of microbial beta-lactamases by detection of fluorescent end products.
Topics: Amidohydrolases; Ampicillin; Bacteriological Techniques; beta-Lactamases; Cephalexin; Cephalosporinase; Cephalosporins; Fluorescence; Gram-Negative Bacteria; Gram-Positive Bacteria; Indicators and Reagents; Penicillinase; Substrate Specificity | 1984 |
Detection of beta lactamase producing bacteria by Cefinase: comparison with three other methods.
Topics: Bacteriological Techniques; beta-Lactamases; Cephalosporins; Haemophilus influenzae; Microbial Sensitivity Tests; Neisseria gonorrhoeae; Penicillins; Staphylococcus; Staphylococcus aureus; Staphylococcus epidermidis | 1983 |
Compounds which increase the permeability of the Pseudomonas aeruginosa outer membrane.
Topics: 1-Naphthylamine; Cell Membrane Permeability; Cephalosporins; Edetic Acid; Fluorescence; Fluorescent Dyes; Magnesium; Muramidase; Pseudomonas aeruginosa | 1984 |
Effect of clavulanic acid on the activities of ten beta-lactam agents against members of the Bacteroides fragilis group.
Topics: Anti-Bacterial Agents; Bacteroides fragilis; Cephalosporins; Clavulanic Acid; Clavulanic Acids; Drug Resistance, Microbial; Indicators and Reagents; Microbial Sensitivity Tests | 1984 |
In vitro evaluation of pyridine-2-azo-p-dimethylaniline cephalosporin, a new diagnostic chromogenic reagent, and comparison with nitrocefin, cephacetrile, and other beta-lactam compounds.
Topics: Bacteria; beta-Lactamases; Cephacetrile; Cephalosporins; Indicators and Reagents | 1982 |
Beta-lactamase testing of staphylococci in a commercial broth microdilution minimum inhibitory concentration system.
Topics: beta-Lactamases; Cephalosporins; Culture Media; Enzyme Induction; Methicillin; Microbial Sensitivity Tests; Staphylococcus | 1982 |
In vitro evaluation of CENTA, a new beta-lactamase-susceptible chromogenic cephalosporin reagent.
Topics: Bacteriological Techniques; beta-Lactamase Inhibitors; beta-Lactamases; Cephalosporins; Citrobacter; Drug Evaluation, Preclinical; Enterobacteriaceae; Escherichia coli; Evaluation Studies as Topic; Indicators and Reagents; Klebsiella; Proteus mirabilis | 1982 |
Mechanisms of resistance to beta-lactam antibiotics amongst Pseudomonas aeruginosa isolates collected in the UK in 1993.
Topics: beta-Lactam Resistance; beta-Lactamase Inhibitors; beta-Lactamases; Carbapenems; Ceftazidime; Cephalosporins; Clavulanic Acid; Clavulanic Acids; Cloxacillin; Enzyme Inhibitors; Humans; Indicators and Reagents; Penicillin Resistance; Penicillins; Pseudomonas aeruginosa | 1995 |
An enzymatic method for assaying sulbactam in human serum: comparison with high performance liquid chromatography.
Topics: Adult; beta-Lactamase Inhibitors; beta-Lactamases; Cephalosporins; Chromatography, High Pressure Liquid; Female; Humans; Male; Middle Aged; Spectrophotometry; Sulbactam | 1995 |
Development, characterization, and initial evaluations of S1. A new chromogenic cephalosporin for beta-lactamase detection.
Topics: Bacteria; Bacteriological Techniques; beta-Lactamases; Cephalosporins; Chromogenic Compounds; Indicators and Reagents; Microbial Sensitivity Tests; Reproducibility of Results; Sensitivity and Specificity | 1995 |
Effects of site-specific mutagenesis of tyrosine 105 in a class A beta-lactamase.
Topics: Bacillus; Base Sequence; beta-Lactamases; Cephalosporins; Chromogenic Compounds; Circular Dichroism; Conserved Sequence; DNA Primers; Hydrogen-Ion Concentration; Indicators and Reagents; Molecular Sequence Data; Mutagenesis, Site-Directed; Penicillin G; Penicillin V; Protein Structure, Secondary; Structure-Activity Relationship; Substrate Specificity; Tyrosine | 1994 |
Evidence of human serum albumin beta-lactamase activity.
Topics: Animals; beta-Lactamases; Binding Sites; Binding, Competitive; Cephalosporins; Goats; Horses; Humans; Hydrogen-Ion Concentration; Ibuprofen; Kinetics; Oleic Acid; Oleic Acids; Probenecid; Serum Albumin; Serum Albumin, Bovine; Species Specificity; Swine; Urea | 1994 |
Interaction of tazobactam with Staphylococcus aureus PC1 beta-lactamase: a molecular modelling and enzyme kinetics study.
Topics: Amino Acid Sequence; beta-Lactamase Inhibitors; beta-Lactamases; Binding Sites; Cephalosporins; Computer Simulation; Models, Molecular; Molecular Sequence Data; Penicillanic Acid; Peptide Fragments; Staphylococcus aureus; Tazobactam | 1994 |
Substrate-induced inactivation of the OXA2 beta-lactamase.
Topics: Anti-Bacterial Agents; beta-Lactamases; Cephalosporins; Enzyme Activation; Hydrolysis; Imipenem; Kinetics; Penicillins | 1993 |
Kinetic interactions of tazobactam with beta-lactamases from all major structural classes.
Topics: Bacterial Proteins; beta-Lactamase Inhibitors; beta-Lactamases; Cephalosporins; Clavulanic Acid; Clavulanic Acids; Hydrolysis; Isoelectric Focusing; Kinetics; Molecular Weight; Penicillanic Acid; Spectrophotometry, Ultraviolet; Tazobactam | 1993 |
An unknown hydrolase activity of human serum albumin: beta-lactamase activity.
Topics: Arginine; beta-Lactamases; Binding Sites; Binding, Competitive; Cephalosporins; Electrophoresis, Polyacrylamide Gel; Histidine; Hot Temperature; Humans; Indicators and Reagents; Lysine; Protein Binding; Serum Albumin; Tryptophan; Tyrosine | 1995 |
Structure and kinetics of the beta-lactamase mutants S70A and K73H from Staphylococcus aureus PC1.
Topics: beta-Lactamases; Binding Sites; Cephalosporins; Cloning, Molecular; Crystallography, X-Ray; DNA Primers; Escherichia coli; Hydrogen-Ion Concentration; Kinetics; Models, Molecular; Mutagenesis, Site-Directed; Penicillin G; Protein Conformation; Staphylococcus aureus | 1996 |
Specific interaction between beta-lactams and soluble penicillin-binding protein 2a from methicillin-resistant Staphylococcus aureus: development of a chromogenic assay.
Topics: Acylation; Anti-Bacterial Agents; Bacterial Proteins; beta-Lactams; Carrier Proteins; Cephalosporins; Chromogenic Compounds; Hexosyltransferases; Kinetics; Lactams; Mass Spectrometry; Methicillin Resistance; Muramoylpentapeptide Carboxypeptidase; Penicillin V; Penicillin-Binding Proteins; Penicillins; Peptidyl Transferases; Protein Binding; Staphylococcus aureus; Thiazoles; Urea | 1996 |
Elimination of the hydrolytic water molecule in a class A beta-lactamase mutant: crystal structure and kinetics.
Topics: Base Sequence; beta-Lactamases; Binding Sites; Cephalosporins; Crystallography, X-Ray; DNA Primers; Electrochemistry; Hydrolysis; Kinetics; Models, Molecular; Molecular Structure; Mutagenesis, Site-Directed; Penicillin G; Point Mutation; Protein Conformation; Staphylococcus aureus; Substrate Specificity; Water | 1996 |
beta-Lactamases are absent from Archaea (archaebacteria).
Topics: Archaea; Bacteria; beta-Lactamases; Cell Membrane; Cell Wall; Cephalosporins; Culture Media | 1996 |
beta-Lactamase bioassay: a simplified method to determine extended-spectrum beta-lactamases (ESBL) in enterobacteria.
Topics: Bacterial Proteins; beta-Lactam Resistance; beta-Lactamases; Biological Assay; Cefotaxime; Cephalosporins; Enterobacteriaceae; Escherichia coli; Isoelectric Focusing; Klebsiella pneumoniae; Microbial Sensitivity Tests; Sensitivity and Specificity | 1997 |
beta-Lactamase producing bacteria in adult periodontitis.
Topics: Actinomyces; Adult; Aggregatibacter actinomycetemcomitans; Amoxicillin; Amoxicillin-Potassium Clavulanate Combination; Anti-Bacterial Agents; Bacteria; Bacteroides; beta-Lactamases; Campylobacter; Cephalosporins; Chromogenic Compounds; Clavulanic Acids; Culture Media; Dental Plaque; Fusobacterium nucleatum; Gingiva; Humans; Indicators and Reagents; Penicillins; Peptostreptococcus; Periodontitis; Porphyromonas gingivalis; Prevotella; Prevotella intermedia | 1997 |
Plasmid analysis of Neisseria gonorrhoeae isolates and dissemination of tetM genes in southern Africa 1993-1995.
Topics: Cephalosporins; Humans; Indicators and Reagents; Neisseria gonorrhoeae; Penicillin Resistance; Plasmids; South Africa; Tetracycline; Tetracycline Resistance | 1997 |
Reaction of soluble penicillin-binding protein 2a of methicillin-resistant Staphylococcus aureus with beta-lactams and acyclic substrates: kinetics in homogeneous solution.
Topics: Anti-Bacterial Agents; Bacterial Proteins; Carrier Proteins; Cephalosporins; Enzyme Inhibitors; Hexosyltransferases; Hydrolysis; Indicators and Reagents; Kinetics; Methicillin Resistance; Muramoylpentapeptide Carboxypeptidase; Penicillin-Binding Proteins; Penicillins; Peptides, Cyclic; Peptidyl Transferases; Recombinant Proteins; Solubility; Spectrometry, Fluorescence; Staphylococcus aureus | 1998 |
Purification, characterization, and kinetic studies of a soluble Bacteroides fragilis metallo-beta-lactamase that provides multiple antibiotic resistance.
Topics: Bacteroides fragilis; Base Sequence; beta-Lactamases; Binding Sites; Catalysis; Cephalosporins; DNA Primers; Electron Spin Resonance Spectroscopy; Enzyme Activation; Hydrogen-Ion Concentration; Hydrolysis; Kinetics; Metals; Solubility; Spectrophotometry, Ultraviolet; Substrate Specificity | 1998 |
Kinetic mechanism of metallo-beta-lactamase L1 from Stenotrophomonas maltophilia.
Topics: Anti-Bacterial Agents; beta-Lactamase Inhibitors; beta-Lactamases; beta-Lactams; Cacodylic Acid; Cephalosporins; Hydrolysis; Indicators and Reagents; Kinetics; Lactams; Software; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Substrate Specificity; Xanthomonas | 1999 |
New options for nitrocefin-based beta-lactamase testing.
Topics: Bacteria; beta-Lactamases; Cephalosporins; Chromogenic Compounds | 1995 |
Mono- and binuclear Zn2+-beta-lactamase. Role of the conserved cysteine in the catalytic mechanism.
Topics: Bacillus cereus; Base Sequence; beta-Lactamases; Binding Sites; Catalysis; Cephalosporins; Cysteine; DNA Primers; Hydrolysis; Kinetics; Mutagenesis, Site-Directed; Penicillin G; Protein Binding; Protein Conformation; Spectrometry, X-Ray Emission; Zinc | 1999 |
Beta-lactamases and outer membrane investigations in beta-lactam-resistant Comamonas acidovorans strains.
Topics: Aminoglycosides; Anti-Bacterial Agents; Bacterial Outer Membrane Proteins; beta-Lactam Resistance; beta-Lactamases; Cell Membrane Permeability; Cephalosporins; Gram-Negative Aerobic Rods and Cocci; Gram-Negative Bacterial Infections; Humans; Microbial Sensitivity Tests | 1999 |
On the mechanism of the metallo-beta-lactamase from Bacteroides fragilis.
Topics: Anions; Bacteroides fragilis; beta-Lactamases; Catalysis; Cephalosporins; Hydrolysis; Hydroxylamine; Hydroxylamines; Indicators and Reagents; Kinetics; Models, Chemical; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Substrate Specificity | 1999 |
Interactions of soluble penicillin-binding protein 2a of methicillin-resistant Staphylococcus aureus with moenomycin.
Topics: Acylation; Anilino Naphthalenesulfonates; Bacterial Proteins; Bambermycins; Carboxypeptidases; Carrier Proteins; Cephalosporins; Fluorescent Dyes; Hexosyltransferases; Kinetics; Methicillin Resistance; Micelles; Models, Chemical; Muramoylpentapeptide Carboxypeptidase; Penicillin-Binding Proteins; Penicillins; Peptidyl Transferases; Serine-Type D-Ala-D-Ala Carboxypeptidase; Solubility; Spectrometry, Fluorescence; Staphylococcus aureus | 1999 |
Preference of Cd(II) and Zn(II) for the two metal sites in Bacillus cereus beta-lactamase II: A perturbed angular correlation of gamma-rays spectroscopic study.
Topics: Alanine; Amino Acid Substitution; Bacillus cereus; Binding Sites; Cadmium; Cations, Divalent; Cephalosporinase; Cephalosporins; Cysteine; Gamma Rays; Hydrolysis; Kinetics; Mutagenesis, Site-Directed; Sodium Chloride; Solutions; Spectrum Analysis; X-Ray Diffraction; Zinc | 1999 |
Comparison of effects of medium composition and atmospheric conditions on detection of Bilophila wadsworthia beta-lactamase by cefinase and cefinase plus methods.
Topics: Aerobiosis; Anaerobiosis; beta-Lactamases; Cephalosporins; Culture Media; Gram-Negative Anaerobic Bacteria; Gram-Negative Bacterial Infections; Humans; Indicators and Reagents; Microbial Sensitivity Tests; Penicillins | 2000 |
The lipopolysaccharide barrier: correlation of antibiotic susceptibility with antibiotic permeability and fluorescent probe binding kinetics.
Topics: Anti-Bacterial Agents; beta-Lactam Resistance; Binding Sites; Cell Membrane Permeability; Cephaloridine; Cephalosporins; Cholesterol; Escherichia coli; Fluorescent Dyes; Lipid Bilayers; Lipopolysaccharides; Microbial Sensitivity Tests; Phosphatidylcholines; Phospholipids; Rhodamines; Salmonella typhimurium; Sulfones; X-Ray Diffraction | 2000 |
The ddcA gene from Streptomyces fradiae encodes an extracellular beta-lactamase with penicillinase and cephalosporinase activities.
Topics: Ampicillin; Bacterial Proteins; beta-Lactamases; Cephalosporinase; Cephalosporins; Cloning, Molecular; Extracellular Space; Gene Expression Regulation, Bacterial; Gene Expression Regulation, Enzymologic; Genes, Bacterial; Indicators and Reagents; Molecular Sequence Data; Penicillin G; Penicillinase; Penicillins; Phylogeny; Plasmids; Sequence Homology, Amino Acid; Streptomyces | 2001 |
Identification and characterization of inhibitors of multidrug resistance efflux pumps in Pseudomonas aeruginosa: novel agents for combination therapy.
Topics: Anti-Infective Agents; Bacterial Outer Membrane Proteins; Carrier Proteins; Cephalosporins; Dipeptides; Drug Resistance, Microbial; Drug Therapy, Combination; Enzyme Inhibitors; Escherichia coli; Levofloxacin; Magnetic Resonance Spectroscopy; Membrane Transport Proteins; Microbial Sensitivity Tests; Ofloxacin; Plasmids; Pseudomonas aeruginosa | 2001 |
Expanding the genetic code: selection of efficient suppressors of four-base codons and identification of "shifty" four-base codons with a library approach in Escherichia coli.
Topics: Amino Acid Sequence; Ampicillin; Anticodon; Base Pairing; Base Sequence; beta-Lactamases; Cephalosporins; Codon; Escherichia coli; Frameshift Mutation; Gene Expression Regulation, Bacterial; Gene Library; Genes, Reporter; Genetic Code; Molecular Sequence Data; Mutagenesis; Protein Biosynthesis; RNA, Transfer; RNA, Transfer, Ser; Serine; Substrate Specificity; Suppression, Genetic | 2001 |
Familial mutations and zinc stoichiometry determine the rate-limiting step of nitrocefin hydrolysis by metallo-beta-lactamase from Bacteroides fragilis.
Topics: Amino Acid Substitution; Arginine; Bacillus cereus; Bacteroides fragilis; beta-Lactamases; Catalysis; Cephalosporins; Cobalt; Cysteine; Dialysis; Hydrolysis; Indicators and Reagents; Kinetics; Metalloproteins; Multigene Family; Mutagenesis, Site-Directed; Recombinant Proteins; Resorcinols; Spectrophotometry, Atomic; Zinc | 2001 |
In vitro susceptibility of Vibrio spp. isolated from the environment.
Topics: Anti-Bacterial Agents; beta-Lactamases; Cephalosporins; DNA, Bacterial; Drug Resistance, Microbial; Indicators and Reagents; Microbial Sensitivity Tests; Plasmids; Polymerase Chain Reaction; Vibrio; Water Microbiology | 2001 |
CENTA as a chromogenic substrate for studying beta-lactamases.
Topics: beta-Lactamases; Cephalosporins; Chromogenic Compounds; Indicators and Reagents; Kinetics; Mycobacterium tuberculosis; Pseudomonas aeruginosa; Staphylococcus aureus | 2001 |
Intermediate in beta-lactam hydrolysis catalyzed by a dinuclear zinc(II) complex: relevance to the mechanism of metallo-beta-lactamase.
Topics: beta-Lactamases; beta-Lactams; Catalysis; Cephalosporins; Dimethyl Sulfoxide; Hydrogen-Ion Concentration; Hydrolysis; Metalloproteins; Solvents; Substrate Specificity; Water; Zinc | 2001 |
Novel mechanism of hydrolysis of therapeutic beta-lactams by Stenotrophomonas maltophilia L1 metallo-beta-lactamase.
Topics: beta-Lactamases; Catalysis; Cefaclor; Cephalosporins; Dose-Response Relationship, Drug; Hydrolysis; Indicators and Reagents; Kinetics; Meropenem; Models, Chemical; Spectrometry, Fluorescence; Stenotrophomonas maltophilia; Temperature; Thienamycins; Time Factors; Tryptophan; Ultraviolet Rays | 2001 |
Cell permeabilization and uptake of antisense peptide-peptide nucleic acid (PNA) into Escherichia coli.
Topics: Amino Acid Sequence; Binding Sites; Cell Line; Cell Membrane; Cephalosporins; Escherichia coli; Kinetics; Magnesium; Magnesium Chloride; Models, Chemical; Models, Genetic; Molecular Sequence Data; Oligonucleotides, Antisense; Peptide Nucleic Acids; Peptides; Protein Binding; Time Factors | 2002 |
Methanolysis of nitrocefin catalyzed by one and two Zn(2+) ions. A simplified model for class B beta-lactamases.
Topics: Algorithms; Anti-Bacterial Agents; Bacteria; beta-Lactamases; beta-Lactams; Binding Sites; Catalysis; Cations; Cephalosporins; Hydrogen-Ion Concentration; Kinetics; Models, Chemical; Molecular Structure; Substrate Specificity; Temperature; Titrimetry; Zinc | 2002 |
Probing substrate binding to metallo-beta-lactamase L1 from Stenotrophomonas maltophilia by using site-directed mutagenesis.
Topics: Asparagine; beta-Lactamases; Binding Sites; Carbapenems; Cephalosporins; Computational Biology; Isoleucine; Kinetics; Metals; Models, Molecular; Mutagenesis, Site-Directed; Penicillins; Phenylalanine; Protein Binding; Serine; Stenotrophomonas maltophilia; Tyrosine | 2002 |
Beta-lactamase protein fragment complementation assays as in vivo and in vitro sensors of protein protein interactions.
Topics: 3-Phosphoinositide-Dependent Protein Kinases; Animals; bcl-Associated Death Protein; beta-Lactamases; Carrier Proteins; Cattle; Cell Line; Cephalosporins; DNA-Binding Proteins; Humans; Immunophilins; Kidney; Leucine; Microscopy, Fluorescence; Peptide Fragments; Peptide Library; Phosphotransferases (Alcohol Group Acceptor); Protein Conformation; Protein Folding; Protein Interaction Mapping; Protein Kinases; Protein Serine-Threonine Kinases; Proteins; Proto-Oncogene Proteins c-bcl-2; Recombinant Fusion Proteins; Reproducibility of Results; Saccharomyces cerevisiae Proteins; Sensitivity and Specificity; Smad3 Protein; TOR Serine-Threonine Kinases; Trans-Activators | 2002 |
Methicillin resistance in staphylococci isolated from subclinical mastitis in sheep.
Topics: Animals; Bacterial Proteins; beta-Lactamases; Carrier Proteins; Cephalosporins; DNA, Bacterial; Female; Hexosyltransferases; Immunodiffusion; Indicators and Reagents; Mastitis; Methicillin Resistance; Microbial Sensitivity Tests; Milk; Muramoylpentapeptide Carboxypeptidase; Penicillin-Binding Proteins; Peptidyl Transferases; Polymerase Chain Reaction; Sheep; Sheep Diseases; Staphylococcal Infections; Staphylococcus | 2003 |
Thiols as classical and slow-binding inhibitors of IMP-1 and other binuclear metallo-beta-lactamases.
Topics: Bacillus cereus; Bacterial Proteins; beta-Lactamase Inhibitors; beta-Lactamases; Binding, Competitive; Catalysis; Cephalosporins; Enzyme Inhibitors; Hydrogen-Ion Concentration; Hydrolysis; Inhibitory Concentration 50; Kinetics; Metalloproteins; Pseudomonas aeruginosa; Spectrometry, Mass, Electrospray Ionization; Spectrophotometry; Sulfhydryl Compounds | 2003 |
Analysis of the importance of the metallo-beta-lactamase active site loop in substrate binding and catalysis.
Topics: beta-Lactamases; Binding Sites; Catalysis; Cephalosporins; Enzyme Inhibitors; Genes, bcl-2; Hydrolysis; Indicators and Reagents; Kinetics; Magnetic Resonance Spectroscopy; Mass Spectrometry; Models, Molecular; Molecular Weight; Mutagenesis, Site-Directed; Mutation; Spectrophotometry, Ultraviolet; Zinc | 2003 |
Role of a solvent-exposed tryptophan in the recognition and binding of antibiotic substrates for a metallo-beta-lactamase.
Topics: Anti-Bacterial Agents; Bacteroides fragilis; beta-Lactamase Inhibitors; beta-Lactamases; Binding Sites; Cephalosporins; Enzyme Inhibitors; Kinetics; Ligands; Magnetic Resonance Spectroscopy; Models, Molecular; Protein Conformation; Solvents; Substrate Specificity; Tryptophan; Zinc | 2003 |
Grafting a new metal ligand in the cocatalytic site of B. cereus metallo-beta-lactamase: structural flexibility without loss of activity.
Topics: Bacillus cereus; beta-Lactamases; Binding Sites; Catalytic Domain; Cephalosporins; Cobalt; Ligands; Magnetic Resonance Spectroscopy; Metals; Models, Molecular; Molecular Sequence Data; Penicillin G; Pliability; Sequence Alignment; Spectrophotometry; Zinc | 2003 |
A fast method for the detection of penicillin resistance in Bacillus anthracis.
Topics: Bacillus anthracis; Cephalosporins; Humans; Indicators and Reagents; Microbial Sensitivity Tests; Penicillin Resistance | 2003 |
La3+-catalyzed methanolysis of N-aryl-beta-lactams and nitrocefin.
Topics: beta-Lactams; Catalysis; Cations; Cephalosporins; Hydrogen-Ion Concentration; Kinetics; Lanthanum; Methanol; Potentiometry | 2003 |
Creation of an allosteric enzyme by domain insertion.
Topics: Allosteric Regulation; Bacterial Proteins; beta-Lactamases; Carrier Proteins; Cephalosporins; Gene Library; Maltose-Binding Proteins; Models, Molecular; Peptide Fragments; Plasmids; Protein Conformation; Protein Structure, Tertiary | 2004 |
The ybxI gene of Bacillus subtilis 168 encodes a class D beta-lactamase of low activity.
Topics: Amino Acid Sequence; Bacillus subtilis; Bacterial Proteins; beta-Lactamases; Bicarbonates; Carrier Proteins; Cephalosporins; Electrophoresis, Polyacrylamide Gel; Genes, Bacterial; Hexosyltransferases; Hydrolysis; Kinetics; Molecular Sequence Data; Muramoylpentapeptide Carboxypeptidase; Penicillin-Binding Proteins; Peptidoglycan; Peptidyl Transferases; Plasmids; Reverse Transcriptase Polymerase Chain Reaction; RNA, Bacterial; RNA, Messenger | 2004 |
Structure of the translocator domain of a bacterial autotransporter.
Topics: Amino Acid Sequence; Cephalosporins; Crystallography, X-Ray; Escherichia coli; Gene Expression; Membrane Transport Proteins; Models, Molecular; Molecular Sequence Data; Neisseria meningitidis; Protein Binding; Protein Folding; Protein Renaturation; Protein Structure, Quaternary; Protein Structure, Secondary; Protein Structure, Tertiary; Protein Transport; Serine Endopeptidases | 2004 |
Characterization of HMRZ-86: a novel chromogenic cephalosporin for the detection of extended-spectrum beta-lactamases.
Topics: Bacteria; beta-Lactamases; Cephalosporins; Drug Resistance, Bacterial; Indicators and Reagents | 2004 |
Exploring the effectiveness of tazobactam against ceftazidime resistant Escherichia coli: insights from the comparison between susceptibility testing and beta-lactamase inhibition.
Topics: Anti-Bacterial Agents; Bacterial Proteins; beta-Lactamase Inhibitors; beta-Lactamases; beta-Lactams; Cefepime; Ceftazidime; Cephalosporins; Drug Resistance, Bacterial; Drug Therapy, Combination; Enzyme Inhibitors; Ertapenem; Escherichia coli; Escherichia coli Infections; Lactams; Microbial Sensitivity Tests; Penicillanic Acid; Tazobactam | 2004 |
Citrobacter koseri and Citrobacter amalonaticus isolates carry highly divergent beta-lactamase genes despite having high levels of biochemical similarity and 16S rRNA sequence homology.
Topics: beta-Lactamases; Cefoxitin; Cephalosporins; Cephamycins; Citrobacter; Citrobacter koseri; Gene Expression Regulation, Bacterial; Microbial Sensitivity Tests; Phylogeny; Reverse Transcriptase Polymerase Chain Reaction; RNA, Ribosomal, 16S; Sequence Homology, Nucleic Acid | 2004 |
Accelerating whole-cell biocatalysis by reducing outer membrane permeability barrier.
Topics: beta-Lactamases; Catalysis; Cell Membrane; Cell Membrane Permeability; Cephalosporins; Escherichia coli; Genetic Engineering; Lipid A; Lipopolysaccharides; Lipoproteins; Membrane Fluidity; Mutagenesis, Site-Directed; Peptides; Subtilisin | 2004 |
A practical synthesis of nitrocefin.
Topics: Catalysis; Cephalosporins; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Stereoisomerism | 2005 |
Genetic analysis of the beta-lactamases of Mycobacterium tuberculosis and Mycobacterium smegmatis and susceptibility to beta-lactam antibiotics.
Topics: Amino Acid Sequence; Anti-Bacterial Agents; beta-Lactamases; beta-Lactams; Cephalosporins; Drug Resistance, Bacterial; Gene Deletion; Humans; Microbial Sensitivity Tests; Molecular Sequence Data; Mycobacterium smegmatis; Mycobacterium tuberculosis; Sequence Alignment | 2005 |
Activation for catalysis of penicillin-binding protein 2a from methicillin-resistant Staphylococcus aureus by bacterial cell wall.
Topics: Catalysis; Cell Wall; Cephalosporins; Circular Dichroism; Methicillin Resistance; Penicillin-Binding Proteins; Peptide Fragments; Peptidoglycan; Staphylococcus aureus | 2005 |
Comparison of phenotypic and genotypic detection of penicillin G resistance of Staphylococcus aureus isolated from bovine intramammary infection.
Topics: Animals; Anti-Bacterial Agents; beta-Lactamases; Cattle; Cephalosporins; DNA, Bacterial; Female; Mastitis, Bovine; Microbial Sensitivity Tests; Penicillin G; Penicillin Resistance; Polymerase Chain Reaction; Staphylococcal Infections; Staphylococcus aureus; Statistics, Nonparametric | 2005 |
Hybrid QM/MM and DFT investigations of the catalytic mechanism and inhibition of the dinuclear zinc metallo-beta-lactamase CcrA from Bacteroides fragilis.
Topics: Bacterial Proteins; Bacteroides fragilis; beta-Lactamase Inhibitors; beta-Lactamases; Carboxylic Acids; Catalysis; Cephalosporins; Computer Simulation; Enzyme Activation; Enzyme Inhibitors; Metalloproteins; Models, Molecular; Protons; Quantum Theory; Thermodynamics; Thiazoles; Zinc | 2005 |
Probing the role of Asp-120(81) of metallo-beta-lactamase (IMP-1) by site-directed mutagenesis, kinetic studies, and X-ray crystallography.
Topics: Aspartic Acid; beta-Lactamases; Binding Sites; Catalysis; Cephalosporins; Conserved Sequence; Crystallization; Crystallography, X-Ray; Hydrogen-Ion Concentration; Hydrolysis; Kinetics; Models, Molecular; Molecular Structure; Mutagenesis, Site-Directed; Recombinant Proteins; Serratia marcescens; Structure-Activity Relationship; Zinc | 2005 |
Further development of the beta-lactamase MutaGen assay and evaluation by comparison with Ames fluctuation tests and the umu test.
Topics: Bacteria; beta-Lactamases; Biological Assay; Bromcresol Purple; Cephalosporins; Environmental Monitoring; Hydrogen-Ion Concentration; Mutagenicity Tests; Mutation; Plasmids | 2005 |
Colorimetric assay for screening compounds against Leishmania amastigotes grown in macrophages.
Topics: Animals; Antiprotozoal Agents; beta-Lactamases; Cephalosporins; Colorimetry; Enzyme-Linked Immunosorbent Assay; Gene Expression; Genes, Reporter; Indicators and Reagents; Leishmania; Macrophages; Mice; Organisms, Genetically Modified | 2005 |
Crystal structure of the Actinomadura R39 DD-peptidase reveals new domains in penicillin-binding proteins.
Topics: Actinomycetales; Bacterial Proteins; Cephalosporins; Cobalt; Crystallography, X-Ray; Indicators and Reagents; Models, Molecular; Penicillins; Protein Structure, Tertiary; Serine-Type D-Ala-D-Ala Carboxypeptidase | 2005 |
AmpC beta-lactamase producing bacterial isolates from Kolkata hospital.
Topics: Anti-Bacterial Agents; Bacteria; Bacterial Proteins; beta-Lactamases; Cefoxitin; Cephalosporins; Clavulanic Acid; Drug Resistance, Bacterial; Enzyme Induction; Hospitals; Humans; India; Isoelectric Focusing; Microbial Sensitivity Tests; Species Specificity | 2005 |
A beta-lactamase with reduced immunogenicity for the targeted delivery of chemotherapeutics using antibody-directed enzyme prodrug therapy.
Topics: Amino Acid Sequence; Animals; Antineoplastic Agents; beta-Lactamases; CD4-Positive T-Lymphocytes; Cell Line; Cell Line, Tumor; Cell Proliferation; Cephalosporins; Chromatography, Affinity; Clinical Trials as Topic; Dose-Response Relationship, Drug; Enterobacter cloacae; Epitopes; Escherichia coli; Female; Humans; Hydrolysis; Immunoglobulin G; Kinetics; Lactams; Leukocytes, Mononuclear; Mice; Mice, Inbred C57BL; Molecular Sequence Data; Peptides; Prodrugs; Recombinant Fusion Proteins; Risk; T-Lymphocytes; Time Factors | 2005 |
Modulation of effector affinity by hinge region mutations also modulates switching activity in an engineered allosteric TEM1 beta-lactamase switch.
Topics: Acylation; Allosteric Regulation; beta-Lactamases; Carrier Proteins; Catalysis; Cephalosporins; Directed Molecular Evolution; Hydrolysis; Hydroxylamine; Kinetics; Maltose; Maltose-Binding Proteins; Models, Molecular; Mutation; Protein Engineering | 2006 |
Sequence-enabled reassembly of beta-lactamase (SEER-LAC): a sensitive method for the detection of double-stranded DNA.
Topics: Base Pair Mismatch; Base Sequence; beta-Lactamases; Cephalosporins; DNA; DNA Probes; DNA-Binding Proteins; Enzyme Activation; Eukaryotic Cells; Feasibility Studies; Hydrolysis; Indicators and Reagents; Molecular Sequence Data; Mutation; Prokaryotic Cells; Protein Structure, Tertiary; Structure-Activity Relationship; Zinc Fingers | 2006 |
[Structure-activity relationships of salicylic acid and its analogs in the inhibitory action on beta-lactamase].
Topics: Anti-Bacterial Agents; beta-Lactamases; Cephalosporins; Inhibitory Concentration 50; Pseudomonas aeruginosa; Salicylates; Structure-Activity Relationship | 2006 |
Inhibition of gene expression and growth by antisense peptide nucleic acids in a multiresistant beta-lactamase-producing Klebsiella pneumoniae strain.
Topics: Antisense Elements (Genetics); beta-Lactamases; Cells, Cultured; Cephalosporins; Chromosomes, Bacterial; DNA, Bacterial; Fibroblasts; Gene Expression Regulation, Bacterial; Gene Silencing; Genes, Reporter; Humans; Indicators and Reagents; Kinetics; Klebsiella pneumoniae; Lac Operon; Peptide Nucleic Acids; RNA, Bacterial; RNA, Messenger | 2007 |
Low-frequency ultrasound increases outer membrane permeability of Pseudomonas aeruginosa.
Topics: Cell Membrane Permeability; Cephalosporins; Edetic Acid; Hydrolysis; Pseudomonas aeruginosa; Ultrasonics | 2006 |
Comparison of tests for detection of beta-lactamase-producing staphylococci.
Topics: Animals; beta-Lactamases; Cattle; Cattle Diseases; Cephalosporins; Coagulase; Colorimetry; Indicators and Reagents; Mastitis, Bovine; Microbial Sensitivity Tests; Polymerase Chain Reaction; Sensitivity and Specificity; Staphylococcal Infections; Staphylococcus; Staphylococcus aureus | 2007 |
Split beta-lactamase sensor for the sequence-specific detection of DNA methylation.
Topics: Base Sequence; beta-Lactamases; Binding Sites; Biosensing Techniques; Cephalosporins; DNA; DNA Methylation; Humans; Hydrolysis; Models, Molecular; Protein Structure, Tertiary; Sensitivity and Specificity | 2007 |
Structural insights into the design of inhibitors for the L1 metallo-beta-lactamase from Stenotrophomonas maltophilia.
Topics: Anti-Bacterial Agents; Apoenzymes; beta-Lactamase Inhibitors; beta-Lactamases; Binding Sites; Captopril; Cephalosporins; Enzyme Inhibitors; Escherichia coli; Hydrogen Bonding; Hydrogen-Ion Concentration; Indicators and Reagents; Inhibitory Concentration 50; Ligands; Models, Molecular; Molecular Structure; Moxalactam; Protein Binding; Protein Structure, Secondary; Stenotrophomonas maltophilia; Stereoisomerism; Substrate Specificity; Sulfates; Water; X-Ray Diffraction; Zinc | 2008 |
Role of the cell envelope in the antibacterial activities of polymyxin B and polymyxin B nonapeptide against Escherichia coli.
Topics: Cell Membrane; Cell Membrane Permeability; Cephalosporins; Escherichia coli; Escherichia coli Proteins; Lipopolysaccharides; Nitrophenols; Periplasmic Proteins; Polymyxin B; Polysaccharides, Bacterial; Time Factors | 2008 |
Substrate specificity of HMRZ-86 for beta-lactamases, including extended-spectrum beta-lactamases (ESBLs).
Topics: Anti-Bacterial Agents; beta-Lactamases; Cephalosporins; Gram-Negative Bacteria; Humans; Kinetics; Substrate Specificity | 2007 |
The effects of antibiotics combined with natural polyphenols against clinical methicillin-resistant Staphylococcus aureus (MRSA).
Topics: Anti-Bacterial Agents; beta-Lactamase Inhibitors; Cephalosporins; Flavonoids; Methicillin Resistance; Microbial Sensitivity Tests; Phenols; Polyphenols; Staphylococcus aureus | 2008 |
Role of the Zn1 and Zn2 sites in metallo-beta-lactamase L1.
Topics: beta-Lactamases; Binding Sites; Cephalosporins; Cobalt; Electron Spin Resonance Spectroscopy; Histidine; Iron; Kinetics; Magnetic Resonance Spectroscopy; Mutagenesis, Site-Directed; Organometallic Compounds; Reference Standards; Time Factors; Zinc | 2008 |
Modified nitrocefin-EDTA method to differentially quantify the induced L1 and L2 beta-lactamases in Stenotrophomonas maltophilia.
Topics: Bacterial Proteins; beta-Lactamase Inhibitors; beta-Lactamases; Cephalosporins; Chelating Agents; DNA, Bacterial; Edetic Acid; Molecular Sequence Data; Phylogeny; Sequence Analysis, DNA; Sequence Homology, Amino Acid; Stenotrophomonas maltophilia | 2008 |
A novel family VIII carboxylesterase derived from a leachate metagenome library exhibits promiscuous beta-lactamase activity on nitrocefin.
Topics: Amino Acid Sequence; Bacteria; Bacterial Proteins; beta-Lactamases; Carboxylesterase; Cephalosporins; Gene Library; Genome, Bacterial; Molecular Sequence Data; Sequence Alignment; Substrate Specificity | 2009 |
Mutation of the active site carboxy-lysine (K70) of OXA-1 beta-lactamase results in a deacylation-deficient enzyme.
Topics: Acids, Acyclic; Amino Acid Substitution; Ampicillin; beta-Lactamases; Binding, Competitive; Biocatalysis; Boron Compounds; Catalytic Domain; Cephalosporins; Electrophoresis, Polyacrylamide Gel; Enzyme Inhibitors; Escherichia coli; Hydrolysis; Kinetics; Lysine; Penicillins; Protein Conformation; Recombinant Proteins; Spectrometry, Fluorescence; Spectrometry, Mass, Electrospray Ionization; Triazines | 2009 |
In vitro activity of the {beta}-lactamase inhibitor NXL104 against KPC-2 carbapenemase and Enterobacteriaceae expressing KPC carbapenemases.
Topics: Anti-Bacterial Agents; Azabicyclo Compounds; beta-Lactamase Inhibitors; beta-Lactamases; beta-Lactams; Cephalosporins; Enterobacteriaceae; Enzyme Inhibitors; Humans; Inhibitory Concentration 50; Microbial Sensitivity Tests; Molecular Structure | 2009 |
Synergistic interaction of eugenol with antibiotics against Gram negative bacteria.
Topics: Anti-Infective Agents; Bacteriolysis; Cell Membrane; Cephalosporins; Drug Synergism; Enterobacteriaceae; Eugenol; Hemolysis; Hydrophobic and Hydrophilic Interactions; Indicators and Reagents; Microbial Sensitivity Tests; Pseudomonas aeruginosa; Syzygium | 2009 |
Effect of synthetic and natural phospholipids on N-acylphosphatidylethanolamine-hydrolyzing phospholipase D activity.
Topics: Cell Line; Cephalosporins; Dose-Response Relationship, Drug; Humans; Molecular Structure; Phospholipase D; Phospholipids; Stereoisomerism; Structure-Activity Relationship | 2009 |
Mechanism of recognition of compounds of diverse structures by the multidrug efflux pump AcrB of Escherichia coli.
Topics: Binding, Competitive; Cephalosporins; Doxorubicin; Drug Resistance, Multiple; Escherichia coli; Escherichia coli Proteins; Fluoresceins; Ligands; Minocycline; Models, Chemical; Models, Molecular; Multidrug Resistance-Associated Proteins; Mutation; Protein Binding | 2010 |
Biochemical and structural characterization of Mycobacterium tuberculosis beta-lactamase with the carbapenems ertapenem and doripenem.
Topics: beta-Lactamases; beta-Lactams; Carbapenems; Cephalosporins; Crystallization; Crystallography, X-Ray; Cyclotrons; Doripenem; Ertapenem; Fourier Analysis; Hydrogen Bonding; Indicators and Reagents; Kinetics; Mass Spectrometry; Models, Molecular; Molecular Structure; Mycobacterium tuberculosis; Protein Conformation | 2010 |
Identification of β-lactamases in human and bovine isolates of Staphylococcus aureus strains having borderline resistance to penicillinase-resistant penicillins (PRPs) with proteomic methods.
Topics: Animals; Anti-Bacterial Agents; beta-Lactamases; Cattle; Cephalosporins; Drug Resistance, Bacterial; Female; Humans; Membrane Proteins; Methicillin-Resistant Staphylococcus aureus; Penicillinase; Penicillins; Proteomics; Staphylococcal Infections; Staphylococcus aureus | 2011 |
Regulation of beta-lactamase activity by remote binding of heme: functional coupling of unrelated proteins through domain insertion.
Topics: Ampicillin; beta-Lactamases; Cephalosporins; Cytochrome b Group; Directed Molecular Evolution; Drug Resistance, Bacterial; Escherichia coli; Escherichia coli Proteins; Heme; Protein Binding; Protein Conformation; Spectrum Analysis | 2010 |
Biochemical and structural characterization of the subclass B1 metallo-β-lactamase VIM-4.
Topics: Ampicillin; Anti-Bacterial Agents; beta-Lactamases; Cephalosporins; Cephalothin; Crystallography, X-Ray; Escherichia coli; Imipenem; Magnetic Resonance Spectroscopy; Meropenem; Penicillin G; Thienamycins | 2011 |
Microflora of root filled teeth with apical periodontitis in Latvian patients.
Topics: Actinomyces; Bacillus; Bacteriological Techniques; beta-Lactamases; Candida albicans; Cephalosporins; Chromogenic Compounds; Dental Pulp Cavity; Enterococcus; Gram-Positive Bacteria; Humans; Indicators and Reagents; Lactobacillus; Latvia; Periapical Periodontitis; Retreatment; Root Canal Therapy; Staphylococcus; Streptococcus; Tooth, Nonvital | 2010 |
[Resistance to B-lactamines of bacteria responsible for endodontic root canal infections].
Topics: Actinomyces; Amoxicillin-Potassium Clavulanate Combination; Anti-Bacterial Agents; Bacteriological Techniques; Bacteroides; beta-Lactam Resistance; beta-Lactamases; Cefoxitin; Cephalosporins; Dental Pulp Cavity; Dental Pulp Necrosis; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; Indicators and Reagents; Peptostreptococcus; Periapical Periodontitis; Prevotella; Streptococcus | 2010 |
Computational studies of bacterial resistance to β-lactam antibiotics: mechanism of covalent inhibition of the penicillin-binding protein 2a (PBP2a).
Topics: Acylation; Anti-Bacterial Agents; Catalytic Domain; Cephalosporins; Methicillin; Methicillin Resistance; Methicillin-Resistant Staphylococcus aureus; Models, Molecular; Penicillin-Binding Proteins; Thermodynamics | 2011 |
Kinetic characterization of a slow-binding inhibitor of Bla2: thiomaltol.
Topics: Anti-Bacterial Agents; Bacillus anthracis; beta-Lactamase Inhibitors; beta-Lactamases; Cephalosporins; Computer Simulation; Enzyme Inhibitors; Inhibitory Concentration 50; Kinetics; Molecular Docking Simulation; Molecular Structure; Pyrans; Thiones | 2013 |
Development of a colorimetric assay for rapid quantitative measurement of clavulanic acid in microbial samples.
Topics: beta-Lactamase Inhibitors; beta-Lactamases; Cephalosporins; Chromatography, High Pressure Liquid; Clavulanic Acid; Colorimetry; Culture Media, Conditioned; Mutation; Reproducibility of Results; Streptomyces | 2012 |
Mechanistic and spectroscopic studies of metallo-β-lactamase NDM-1.
Topics: Bacterial Proteins; beta-Lactamases; Binding Sites; Catalytic Domain; Cephalosporins; Kinetics; Light; Recombinant Fusion Proteins; Scattering, Radiation; Thrombin; X-Ray Absorption Spectroscopy; Zinc | 2012 |
Carboxylation and decarboxylation of active site Lys 84 controls the activity of OXA-24 β-lactamase of Acinetobacter baumannii: Raman crystallographic and solution evidence.
Topics: Acinetobacter baumannii; beta-Lactamase Inhibitors; beta-Lactamases; Catalytic Domain; Cephalosporins; Decarboxylation; Enzyme Inhibitors; Lysine; Spectrum Analysis, Raman | 2012 |
Substitutions at position 105 in SHV family β-lactamases decrease catalytic efficiency and cause inhibitor resistance.
Topics: Amino Acid Substitution; Ampicillin; Anti-Bacterial Agents; beta-Lactam Resistance; beta-Lactamases; Biocatalysis; Cephalosporins; Clavulanic Acid; Enzyme Inhibitors; Escherichia coli; Kinetics; Meropenem; Microbial Sensitivity Tests; Molecular Docking Simulation; Mutagenesis, Site-Directed; Structure-Activity Relationship; Substrate Specificity; Sulbactam; Thienamycins | 2012 |
Structure-based computational study of the hydrolysis of New Delhi metallo-β-lactmase-1.
Topics: Ampicillin; beta-Lactamases; Catalysis; Cephalosporins; Hydrogen Bonding; Hydrolysis; Meropenem; Molecular Dynamics Simulation; Protein Binding; Protein Structure, Secondary; Substrate Specificity; Thienamycins | 2013 |
Kinetic characterization of hydrolysis of nitrocefin, cefoxitin, and meropenem by β-lactamase from Mycobacterium tuberculosis.
Topics: Acylation; Bacterial Proteins; beta-Lactam Resistance; beta-Lactamases; Cefoxitin; Cephalosporins; Hydrogen-Ion Concentration; Hydrolysis; Kinetics; Meropenem; Mycobacterium tuberculosis; Solvents; Thienamycins | 2013 |
Antibiotic trapping by plasmid-encoded CMY-2 β-lactamase combined with reduced outer membrane permeability as a mechanism of carbapenem resistance in Escherichia coli.
Topics: Anti-Bacterial Agents; Bacterial Outer Membrane Proteins; beta-Lactamases; Cell Membrane Permeability; Cephalosporins; Drug Resistance, Multiple, Bacterial; Enzyme Activation; Escherichia coli; Escherichia coli Infections; Escherichia coli Proteins; Female; Humans; Hydrolysis; Meropenem; Microbial Sensitivity Tests; Periplasm; Plasmids; Protein Binding; Thienamycins; Young Adult | 2013 |
Insignificant β-lactamase activity of human serum albumin: no panic to nonmicrobial-based drug resistance.
Topics: Anti-Bacterial Agents; beta-Lactamases; Cephalosporins; Drug Resistance; Humans; Kinetics; Naphthols; Serum Albumin | 2013 |
Some ligands enhance the efflux of other ligands by the Escherichia coli multidrug pump AcrB.
Topics: Arginine; Benzene; Cefamandole; Cephalosporins; Chloramphenicol; Escherichia coli; Escherichia coli Proteins; Kinetics; Ligands; Minocycline; Molecular Docking Simulation; Molecular Dynamics Simulation; Multidrug Resistance-Associated Proteins; Protein Conformation; Protein Multimerization; Thermodynamics | 2013 |
Beta-lactamic resistance profiles in Porphyromonas, Prevotella, and Parvimonas species isolated from acute endodontic infections.
Topics: Amoxicillin; Amoxicillin-Potassium Clavulanate Combination; Anti-Bacterial Agents; Bacteroidaceae Infections; beta-Lactam Resistance; beta-Lactamase Inhibitors; beta-Lactamases; Cephalosporins; Dental Pulp Diseases; Gram-Positive Bacterial Infections; Humans; Indicators and Reagents; Microbial Sensitivity Tests; Penicillin G; Peptostreptococcus; Phenotype; Porphyromonas; Porphyromonas endodontalis; Porphyromonas gingivalis; Prevotella; Prevotella intermedia; Prevotella nigrescens | 2014 |
Development of β -lactamase as a tool for monitoring conditional gene expression by a tetracycline-riboswitch in Methanosarcina acetivorans.
Topics: Anaerobiosis; Artificial Gene Fusion; beta-Lactamases; Cephalosporins; Escherichia coli; Gene Expression Profiling; Gene Expression Regulation; Genes, Reporter; Indicators and Reagents; Methanosarcina; Riboswitch; Tetracycline | 2014 |
Amperometric detection of extended-spectrum β-lactamase activity: application to the characterization of resistant E. coli strains.
Topics: Anti-Bacterial Agents; beta-Lactamases; Cephalosporins; Drug Resistance, Bacterial; Electrochemistry; Enzyme Assays; Escherichia coli; Hydrolysis | 2015 |
Inhibiting the VIM-2 Metallo-β-Lactamase by Graphene Oxide and Carbon Nanotubes.
Topics: Adsorption; Animals; beta-Lactamases; Cattle; Cephalosporins; Circular Dichroism; Enzyme Inhibitors; Graphite; Hydrolysis; Kinetics; Nanostructures; Nanotubes, Carbon; Oxides; Serum Albumin, Bovine; Sodium Chloride; Zinc | 2015 |
Development of a novel chromogenic method, Penta-well test, for rapid prediction of β-lactamase classes produced in clinical Enterobacteriaceae isolates.
Topics: Bacteriological Techniques; beta-Lactamases; Cephalosporins; Chromogenic Compounds; Enterobacteriaceae; Enterobacteriaceae Infections; Humans; Hydrolysis; Sensitivity and Specificity; Time Factors | 2015 |
Assay for drug discovery: Synthesis and testing of nitrocefin analogues for use as β-lactamase substrates.
Topics: beta-Lactamases; Biocatalysis; Cephalosporins; Chemistry Techniques, Synthetic; Drug Evaluation, Preclinical; Hydrolysis; Kinetics | 2015 |
Reversal of the Drug Binding Pocket Defects of the AcrB Multidrug Efflux Pump Protein of Escherichia coli.
Topics: Amino Acid Substitution; Anti-Bacterial Agents; Binding Sites; Cephalosporins; Computational Biology; Drug Resistance, Multiple, Bacterial; Escherichia coli; Escherichia coli Proteins; Multidrug Resistance-Associated Proteins; Mutation; Protein Conformation | 2015 |
Susceptibility to ceftriaxone and occurrence of penicillinase plasmids in Neisseria gonorrhoeae strains isolated in Poland in 2012-2013.
Topics: Anti-Bacterial Agents; Ceftriaxone; Cephalosporins; Female; Gonorrhea; Humans; Male; Microbial Sensitivity Tests; Neisseria gonorrhoeae; Penicillinase; Penicillins; Plasmids; Poland | 2016 |
Novel Piperazine Arylideneimidazolones Inhibit the AcrAB-TolC Pump in Escherichia coli and Simultaneously Act as Fluorescent Membrane Probes in a Combined Real-Time Influx and Efflux Assay.
Topics: Anti-Bacterial Agents; Bacterial Outer Membrane Proteins; Biological Assay; Biological Transport; Cell Membrane; Cephalosporins; Clarithromycin; Drug Synergism; Escherichia coli; Escherichia coli Proteins; Fluorescent Dyes; Gene Expression; Imidazoles; Indicators and Reagents; Kinetics; Levofloxacin; Linezolid; Membrane Proteins; Membrane Transport Proteins; Microbial Sensitivity Tests; Oxacillin; Piperazines; Protein Kinases; Repressor Proteins; Rifampin | 2016 |
Prodigiosin - A Multifaceted Escherichia coli Antimicrobial Agent.
Topics: Anti-Bacterial Agents; Carbon Dioxide; Cell Membrane; Cell Membrane Permeability; Cephalosporins; Escherichia coli; Gene Expression Regulation, Bacterial; Hydrolysis; Microbial Viability; Prodigiosin | 2016 |
AIM-1: An Antibiotic-Degrading Metallohydrolase That Displays Mechanistic Flexibility.
Topics: Anti-Bacterial Agents; Aurora Kinase B; beta-Lactamases; Cephalosporins; Humans; Kinetics; Substrate Specificity | 2016 |
Effect of site-directed mutations in multidrug efflux pump AcrB examined by quantitative efflux assays.
Topics: Amides; Binding Sites; Cephalosporins; Escherichia coli Proteins; Molecular Docking Simulation; Multidrug Resistance-Associated Proteins; Mutagenesis, Site-Directed; Protein Binding; Protein Interaction Mapping; Structure-Activity Relationship | 2016 |
New amphiphilic neamine conjugates bearing a metal binding motif active against MDR E. aerogenes Gram-negative bacteria.
Topics: Anti-Bacterial Agents; Cell Membrane Permeability; Cephalosporins; DNA, Bacterial; Drug Resistance, Multiple, Bacterial; Enterobacter aerogenes; Escherichia coli; Framycetin; Hydrolysis; Hydrophobic and Hydrophilic Interactions; Organometallic Compounds | 2017 |
Substitutions in PBP2b from β-Lactam-resistant
Topics: Amino Acid Sequence; beta-Lactams; Cephalosporins; Drug Resistance, Bacterial; Penicillin-Binding Proteins; Protein Denaturation; Recombinant Proteins; Sequence Homology, Amino Acid; Streptococcus pneumoniae | 2017 |
Inhibition by Avibactam and Clavulanate of the β-Lactamases KPC-2 and CTX-M-15 Harboring the Substitution N
Topics: Amino Acid Motifs; Amino Acid Substitution; Amoxicillin; Anti-Bacterial Agents; Azabicyclo Compounds; Aztreonam; beta-Lactamases; Ceftaroline; Ceftazidime; Cephalosporins; Clavulanic Acid; Cloning, Molecular; Drug Combinations; Escherichia coli; Gene Expression; Kinetics; Mutation; Recombinant Proteins; Reverse Genetics; Substrate Specificity | 2017 |
Mutation in an Unannotated Protein Confers Carbapenem Resistance in Mycobacterium tuberculosis.
Topics: Amino Acid Sequence; Amino Acid Substitution; Anti-Bacterial Agents; Bacterial Proteins; Base Sequence; beta-Lactam Resistance; Cephalosporins; Clavulanic Acid; DNA, Intergenic; Gene Expression; Genetic Loci; Humans; Meropenem; Microbial Sensitivity Tests; Mutation; Mycobacterium tuberculosis; Open Reading Frames; Protein Binding; Thienamycins; Tuberculosis, Multidrug-Resistant | 2017 |
Reaction mechanism of the metallohydrolase CpsB from Streptococcus pneumoniae, a promising target for novel antimicrobial agents.
Topics: Anti-Infective Agents; Bacterial Proteins; Binding Sites; Biocatalysis; Calorimetry; Catalytic Domain; Cephalosporins; Circular Dichroism; Cobalt; Crystallography, X-Ray; Electron Spin Resonance Spectroscopy; Hydrolysis; Kinetics; Manganese; Protein Tyrosine Phosphatases; Streptococcus pneumoniae | 2017 |
Reversible inactivation of a peptidoglycan transpeptidase by a β-lactam antibiotic mediated by β-lactam-ring recyclization in the enzyme active site.
Topics: Acylation; Aminoacyltransferases; Anti-Bacterial Agents; Bacterial Proteins; beta-Lactams; Catalytic Domain; Cephalosporins; Cyclization; Enterococcus faecium; Mass Spectrometry; Spectrophotometry | 2017 |
Effect of β-lactamase production and β-lactam instability on MIC testing results for Mycobacterium abscessus.
Topics: Anti-Bacterial Agents; beta-Lactamases; beta-Lactams; Cefoxitin; Cephalosporins; Drug Stability; Humans; Imipenem; Meropenem; Microbial Sensitivity Tests; Mutation; Mycobacterium abscessus; Mycobacterium Infections, Nontuberculous; Thienamycins | 2017 |
A nitrocefin disc supplemented with ertapenem for rapid screening of carbapenemase-producing Enterobacteriaceae.
Topics: Anti-Bacterial Agents; Bacterial Proteins; beta-Lactamases; beta-Lactams; Carbapenem-Resistant Enterobacteriaceae; Carbapenems; Cephalosporins; Disk Diffusion Antimicrobial Tests; Enterobacteriaceae; Enterobacteriaceae Infections; Ertapenem; Humans; Microbial Sensitivity Tests; Sensitivity and Specificity | 2018 |
A comparative study for detection of extended spectrum β-lactamase (ESBL) production by Enteroaggregative Escherichia coli (EAEC) strains using double disc, nitrocefin and PCR assays.
Topics: Animals; Anti-Bacterial Agents; beta-Lactamases; Cephalosporins; DNA, Bacterial; Escherichia coli; Escherichia coli Infections; Humans; Microbial Sensitivity Tests; Polymerase Chain Reaction | 2018 |
Paper-Based Enzyme Competition Assay for Detecting Falsified β-Lactam Antibiotics.
Topics: Anti-Bacterial Agents; beta-Lactamases; beta-Lactams; Cephalosporins; Counterfeit Drugs; Enzyme Assays; Equipment Design; Microfluidic Analytical Techniques; Paper; Tablets | 2018 |
An Enzyme-Mediated Amplification Strategy Enables Detection of β-Lactamase Activity Directly in Unprocessed Clinical Samples for Phenotypic Detection of β-Lactam Resistance.
Topics: Bacterial Infections; beta-Lactam Resistance; beta-Lactamases; Cephalosporins; Humans; Limit of Detection | 2018 |
Topics: Animals; Anti-Bacterial Agents; Bacterial Proteins; beta-Lactamases; Ceftazidime; Cephalosporins; Disease Models, Animal; Drug Therapy, Combination; Enzyme Inhibitors; Escherichia coli; Escherichia coli Infections; Hydrolysis; Indicators and Reagents; Mice; Microbial Sensitivity Tests; NADP; Survival Analysis; Treatment Outcome | 2018 |
Nitro-Carba test, a novel and simple chromogenic phenotypic method for rapid screening of carbapenemase-producing Enterobacteriaceae.
Topics: Bacterial Proteins; Bacteriological Techniques; beta-Lactamases; Carbapenem-Resistant Enterobacteriaceae; Carbapenems; Cephalosporins; Enterobacteriaceae Infections; Humans; Hydrolysis; Microbial Sensitivity Tests; Reproducibility of Results | 2019 |
Evaluation of biochemical and molecular polymorphism in extended spectrum β-lactamases of Mycobacterium tuberculosis clinical isolates.
Topics: Anti-Bacterial Agents; beta-Lactam Resistance; beta-Lactamases; beta-Lactams; Blotting, Southern; Cefotaxime; Cephalosporins; Clavulanic Acid; Humans; Isoelectric Focusing; Kinetics; Mycobacterium tuberculosis; Polymerase Chain Reaction; Tuberculosis | 2019 |
Molecular modeling and QM/MM calculation clarify the catalytic mechanism of β-lactamase N1.
Topics: Anti-Bacterial Agents; beta-Lactamases; beta-Lactams; Catalysis; Catalytic Domain; Cephalosporins; Humans; Hydrolysis; Kinetics; Methicillin-Resistant Staphylococcus aureus; Models, Molecular; Molecular Dynamics Simulation | 2019 |
Bio-surfactin stabilised silver nanoparticles exert inhibitory effect over New-Delhi metallo-beta-lactamases (NDMs) and the cells harbouring NDMs.
Topics: Anti-Bacterial Agents; beta-Lactamase Inhibitors; beta-Lactamases; beta-Lactams; Biofilms; Cephalosporins; Escherichia coli; Escherichia coli Infections; Metal Nanoparticles; Microbial Sensitivity Tests; Silver; Surface-Active Agents | 2019 |
Resistance to piperacillin/tazobactam in Escherichia coli resulting from extensive IS26-associated gene amplification of blaTEM-1.
Topics: Anti-Bacterial Agents; beta-Lactamase Inhibitors; beta-Lactamases; Cephalosporins; Drug Resistance, Multiple, Bacterial; Escherichia coli; Humans; Microbial Sensitivity Tests; Piperacillin, Tazobactam Drug Combination; Sequence Analysis, DNA | 2019 |
Exploration of the antibiotic potentiating activity of indolglyoxylpolyamines.
Topics: Anti-Bacterial Agents; Cell Line; Cell Membrane Permeability; Cell Survival; Cephalosporins; Gram-Negative Bacteria; Hemolysis; Humans; Hydrolysis; Indoles; Microbial Sensitivity Tests; Signal Transduction; Spermine | 2019 |
Effect of Amoxicillin in combination with Imipenem-Relebactam against Mycobacterium abscessus.
Topics: Amoxicillin; Azabicyclo Compounds; beta-Lactamase Inhibitors; beta-Lactamases; Binding Sites; Cephalosporins; Disk Diffusion Antimicrobial Tests; Drug Resistance, Multiple, Bacterial; Drug Synergism; Drug Therapy, Combination; Imipenem; Microbial Sensitivity Tests; Molecular Docking Simulation; Mycobacterium abscessus; Mycobacterium Infections, Nontuberculous; Plasmids | 2020 |
Development of a rapid phenotypic test on a microfluidic device for carbapenemase detection using the chromogenic compound nitrocefin.
Topics: Bacterial Proteins; Bacteriological Techniques; beta-Lactamases; Cephalosporins; Colorimetry; Enterobacteriaceae; Hydrolysis; Indicators and Reagents; Lab-On-A-Chip Devices; Microbial Sensitivity Tests; Microfluidics; Miniaturization; Phenotype; Pseudomonas; Sensitivity and Specificity | 2020 |
Prior exposure of agriculture cephalosporin ceftiofur impaired conjugation of bla
Topics: Agriculture; Animals; Anti-Bacterial Agents; Bacterial Proteins; Ceftriaxone; Cephalosporin Resistance; Cephalosporins; Conjugation, Genetic; Humans; Plasmids; Salmonella enterica | 2020 |
Helicobacter pylori patient isolates from South Africa and Nigeria differ in virulence factor pathogenicity profile and associated gastric disease outcome.
Topics: Breath Tests; Cephalosporins; Endoscopy; Evolution, Molecular; Female; Geography; Helicobacter pylori; Humans; Male; Microbial Sensitivity Tests; Nigeria; Phenotype; Phylogeny; Polymerase Chain Reaction; Prevalence; South Africa; Stomach Diseases; Surveys and Questionnaires; Urea; Virulence; Virulence Factors | 2020 |
Performance of penicillinase detection tests in Staphylococcus epidermidis: comparison of different phenotypic methods.
Topics: Algorithms; Anti-Bacterial Agents; Cephalosporins; Genes, Bacterial; Humans; Microbial Sensitivity Tests; Penicillin G; Penicillin Resistance; Penicillinase; Phenotype; Polymerase Chain Reaction; Sensitivity and Specificity; Staphylococcal Infections; Staphylococcus epidermidis | 2020 |
Characterization of Interactions between CTX-M-15 and Clavulanic Acid, Desfuroylceftiofur, Ceftiofur, Ampicillin, and Nitrocefin.
Topics: Ampicillin; Anti-Bacterial Agents; beta-Lactamases; Cephalosporins; Clavulanic Acid; Microbial Sensitivity Tests; Molecular Docking Simulation | 2022 |
In vitro Activity of Ceftaroline Against an International Collection of Kingella kingae Isolates Recovered From Carriers and Invasive Infections.
Topics: Anti-Bacterial Agents; Bacteremia; beta-Lactamases; Ceftaroline; Cephalosporins; Child; Child, Preschool; Endocarditis; Humans; Kingella kingae; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests | 2023 |