cephalosporin c has been researched along with l 658758 in 25 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 22 (88.00) | 18.2507 |
| 2000's | 2 (8.00) | 29.6817 |
| 2010's | 1 (4.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ashe, BM; Ball, RG; Blacklock, TJ; Bonney, RJ; Brause, KA; Chandler, GO; Cotton, M; Davies, P; Finke, PE; Shah, SK | 1 |
| Agarwal, L; Davies, P; Dijkman, JH; Fletcher, D; Keenan, KP; Kramps, JA; Osinga, D; Rudolphus, A; Stolk, J | 1 |
| Ashe, BM; Doherty, JB; Finke, PE; Gale, P; Green, BG; Hagmann, WK; Knight, WB; Maycock, AL; Shah, SK; Weston, H | 1 |
| Ashe, BM; Doherty, J; Finke, P; Green, BG; Hagmann, W; Lark, M; Mao, J; Maycock, A; Moore, V; Weston, H | 1 |
| Arfors, KE; Rosengren, S | 1 |
| Dahlgren, ME; Doherty, JB; Fletcher, D; Frankenfield, D; Hand, K; Mao, J; Mumford, RA; Nolan, T; Schaffer, L; Williams, H | 1 |
| Ashe, BM; Bonney, RJ; Davies, P; Dorn, C; Finke, P; Fletcher, D; Hanlon, WA; Humes, JL; Maycock, A; Mumford, RA | 1 |
| Davies, P; Dellea, PS; Fletcher, DS; Humes, JL; Opas, EE | 1 |
| Granger, DN; Zimmerman, BJ | 1 |
| Bonney, RJ; Davies, P; Doherty, JB; Finke, PE; Fletcher, DS; Keenan, K; Osinga, DG; Shah, SK | 1 |
| Anderson, DC; Cepinskas, G; Granger, DN; Kvietys, PR; Wolf, RE; Yoshida, N | 1 |
| Davies, P; Dorn, C; Finke, P; Hanlon, WA; Humes, JL; Mumford, RA; Pacholok, SG | 1 |
| Coles, GA; Davies, M; Donovan, KL; Williams, JD | 1 |
| Bienvenu, K; Granger, DN; Harris, N | 1 |
| Granger, DN; Grisham, MD; Kubes, P; Smith, R | 1 |
| Johnston, FL; Kanwar, S; Kubes, P; Reinhardt, PH; Woodman, RC | 1 |
| Carden, DL; Korthuis, RJ | 1 |
| Harada, N; Liu, W; Murakami, K; Okabe, H; Okajima, K; Takatsuki, K; Uchiba, M | 1 |
| Brain, JD; Humes, JL; Mumford, RA; Rees, DD; Wohl, ME | 1 |
| Johno, M; Murakami, K; Naruo, M; Okajima, K; Taoka, Y | 1 |
| Alexander, S; Carden, D; Moak, C; Robinson-Jackson, S; Willis, BH; Xiao, F | 1 |
| Harada, N; Irie, T; Isobe, H; Liu, W; Murakami, K; Okajima, K | 1 |
| Harada, N; Mori, M; Okajima, K; Uchiba, M | 1 |
| Harada, N; Isobe, H; Okajima, K | 1 |
| Harada, N; Kawai, M; Okajima, K; Takeyama, H | 1 |
1 review(s) available for cephalosporin c and l 658758
| Article | Year |
|---|---|
The discovery and biologic properties of cephalosporin-based inhibitors of PMN elastase.
Topics: Cephalosporins; Humans; Leukocyte Elastase; Pancreatic Elastase; Pyrrolidines | 1991 |
24 other study(ies) available for cephalosporin c and l 658758
| Article | Year |
|---|---|
Inhibition of human leukocyte elastase. 4. Selection of a substituted cephalosporin (L-658,758) as a topical aerosol.
Topics: Administration, Topical; Aerosols; Animals; Cephalosporins; Cricetinae; Humans; Leukocyte Elastase; Molecular Structure; Pancreatic Elastase; Pyrrolidines; Rats; X-Ray Diffraction | 1992 |
Induction of emphysema and bronchial mucus cell hyperplasia by intratracheal instillation of lipopolysaccharide in the hamster.
Topics: Animals; Bronchi; Cell Separation; Cephalosporins; Cricetinae; Emphysema; Hyperplasia; Injections; Lipopolysaccharides; Mesocricetus; Mucous Membrane; Neutrophils; Pancreatic Elastase; Pyrrolidines; Trachea | 1992 |
Mechanism of inhibition of human leukocyte elastase by two cephalosporin derivatives.
Topics: Catalysis; Cephalosporins; Chromatography, High Pressure Liquid; Humans; Kinetics; Leukocyte Elastase; Pancreatic Elastase; Pyrrolidines; Spectrophotometry, Ultraviolet | 1992 |
PMN elastases: a comparison of the specificity of human isozymes and the enzyme from other species toward substrates and inhibitors.
Topics: Amino Acid Sequence; Animals; Cephalosporins; Humans; Isoenzymes; Kinetics; Leukocyte Elastase; Molecular Sequence Data; Neutrophils; Oligopeptides; Pancreatic Elastase; Pyrrolidines; Sequence Homology, Nucleic Acid; Species Specificity; Sputum; Substrate Specificity | 1991 |
Polycations induce microvascular leakage of macromolecules in hamster cheek pouch.
Topics: Animals; Capillaries; Capillary Permeability; Cations; Cephalosporins; Cheek; Cricetinae; Dextran Sulfate; Humans; Leukocyte Elastase; Leukocytes; Male; Mast Cells; Mesocricetus; Microcirculation; Pancreatic Elastase; Polylysine; Pyrilamine; Pyrrolidines | 1991 |
Direct assay of A alpha(1-21), a PMN elastase-specific cleavage product of fibrinogen, in the chimpanzee.
Topics: Animals; Calcimycin; Cephalosporins; Fibrinogen; Leukocyte Elastase; Pan troglodytes; Pancreatic Elastase; Peptide Fragments; Pyrrolidines; Radioimmunoassay | 1991 |
The in vitro and in vivo recovery of PMN elastase:beta-lactam inhibitor complexes by cation exchange chromatography.
Topics: Animals; beta-Lactamase Inhibitors; Cephalosporins; Chromatography, Ion Exchange; Cricetinae; Leukocyte Elastase; Pancreatic Elastase; Pyrrolidines | 1991 |
Reperfusion-induced leukocyte infiltration: role of elastase.
Topics: Animals; Cats; Cell Adhesion; Cephalosporins; Intestinal Mucosa; Intestine, Small; Ischemia; Leukocytes; Neutrophils; Pancreatic Elastase; Peroxidase; Proteins; Pyrrolidines; Reperfusion; Serine Proteinase Inhibitors; Serpins; Splanchnic Circulation; Venules | 1990 |
An inhibitor of leukocyte elastase prevents immune complex-mediated hemorrhage in the rat lung.
Topics: Amino Acid Chloromethyl Ketones; Amino Acid Sequence; Animals; Antigen-Antibody Complex; Cephalosporins; Hemorrhage; Leukocyte Elastase; Lung Diseases; Male; Molecular Sequence Data; Neutrophils; Pancreatic Elastase; Rats | 1995 |
Aspirin-induced, neutrophil-mediated injury to vascular endothelium.
Topics: Adult; Antibodies, Monoclonal; Aspirin; Catalase; Cell Adhesion; Cell Size; Cells, Cultured; Cephalosporins; Endothelium, Vascular; Humans; Inflammation; Leukocyte Elastase; Macrophage-1 Antigen; Neutrophils; Pancreatic Elastase; Superoxide Dismutase | 1995 |
Formation of polymorphonuclear leukocyte elastase: alpha 1 proteinase inhibitor complex and A alpha (1-21) fibrinopeptide in human blood stimulated with the calcium ionophore A23187. A model to characterize inhibitors of polymorphonuclear leukocyte elasta
Topics: alpha 1-Antitrypsin; Calcimycin; Cephalosporins; Chlorobenzoates; Dose-Response Relationship, Drug; Fibrin Fibrinogen Degradation Products; Humans; In Vitro Techniques; Leukocyte Elastase; Neutrophils; Oligopeptides; Pancreatic Elastase; Pyrrolidines | 1995 |
Relative roles of elastase and reactive oxygen species in the degradation of human glomerular basement membrane by intact human neutrophils.
Topics: alpha 1-Antitrypsin; Basement Membrane; Catecholamines; Cephalosporins; Collagen; Glomerulonephritis; Humans; Imidazolines; Immunoglobulin G; Kidney Glomerulus; Neutrophils; Pancreatic Elastase; Pyrrolidines; Reactive Oxygen Species; Respiratory Burst | 1994 |
Modulation of leukocyte migration in mesenteric interstitium.
Topics: Animals; Antibodies, Monoclonal; CD18 Antigens; Cephalosporins; Chemotaxis, Leukocyte; Ischemia; Leukocytes; Leukotriene B4; Male; Microscopy, Video; N-Formylmethionine Leucyl-Phenylalanine; Pancreatic Elastase; Platelet Activating Factor; Pyrrolidines; Rats; Rats, Sprague-Dawley; Reperfusion; Serpins; Serum Albumin; Splanchnic Circulation; Time Factors | 1994 |
Neutrophil-mediated proteolysis. Differential roles for cathepsin G and elastase.
Topics: Amino Acid Chloromethyl Ketones; Amino Acid Sequence; Antibodies, Monoclonal; Cathepsin G; Cathepsins; Cephalosporins; Fibronectins; Humans; Leukocyte Elastase; Molecular Sequence Data; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Pancreatic Elastase; Pyrrolidines; Serine Endopeptidases; Serpins; Tetradecanoylphorbol Acetate | 1993 |
Effects of human neutrophil elastase (HNE) on neutrophil function in vitro and in inflamed microvessels.
Topics: Animals; Cell Adhesion; Cephalosporins; Chemotaxis, Leukocyte; Endothelium, Vascular; Humans; Inflammation; Leukocyte Elastase; Male; Microcirculation; Neutrophils; Pancreatic Elastase; Platelet Activating Factor; Pyrrolidines; Rats; Rats, Wistar; Splanchnic Circulation; Superoxides; Tetradecanoylphorbol Acetate; Umbilical Veins; Venules | 1993 |
Protease inhibition attenuates microvascular dysfunction in postischemic skeletal muscle.
Topics: Amino Acid Chloromethyl Ketones; Animals; Capillary Permeability; Cephalosporins; Dogs; Female; Ischemia; Leukocyte Elastase; Male; Microcirculation; Muscle, Skeletal; Neutrophils; Pancreatic Elastase; Peroxidase; Protease Inhibitors; Proteins; Reperfusion; Serine Proteinase Inhibitors; Serpins | 1996 |
Role of granulocyte elastase in indomethacin-induced gastric mucosal lesion formation in rats.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cephalosporins; Cimetidine; Gastric Mucosa; Glycine; Granulocytes; Indomethacin; Leukocyte Elastase; Male; Methotrexate; Microcirculation; Neutrophil Activation; Rats; Rats, Wistar; Serine Proteinase Inhibitors; Specific Pathogen-Free Organisms; Stomach Diseases; Sulfonamides | 1997 |
Inhibition of neutrophil elastase in CF sputum by L-658,758.
Topics: Adult; Animals; Cephalosporins; Cystic Fibrosis; Humans; Leukocyte Elastase; Mice; Serine Proteinase Inhibitors; Sputum | 1997 |
Role of neutrophil elastase in compression-induced spinal cord injury in rats.
Topics: Animals; Cephalosporins; Leukocyte Elastase; Leukopenia; Male; Mechlorethamine; Peroxidase; Proteins; Rats; Rats, Wistar; Serpins; Spinal Cord; Spinal Cord Compression; Spinal Cord Injuries | 1998 |
Neutrophil elastase promotes lung microvascular injury and proteolysis of endothelial cadherins.
Topics: Animals; Blood Pressure; Bronchoalveolar Lavage Fluid; Cadherins; Capillaries; Capillary Permeability; Cells, Cultured; Cephalosporins; Endothelium, Vascular; Humans; In Vitro Techniques; Intestines; Ischemia; Leukocyte Elastase; Lung; Male; Neutrophils; Peroxidase; Pulmonary Circulation; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Respiratory Distress Syndrome; Serine Proteinase Inhibitors; Umbilical Veins | 1998 |
Role of neutrophil elastase in stress-induced gastric mucosal injury in rats.
Topics: Animals; Capillary Permeability; Cephalosporins; Disease Models, Animal; Gastric Mucosa; Glycine; Leukocyte Elastase; Leukopenia; Male; Mechlorethamine; Neutrophils; Peptic Ulcer; Peroxidase; Rats; Rats, Wistar; Restraint, Physical; Serine Proteinase Inhibitors; Specific Pathogen-Free Organisms; Stress, Physiological; Sulfonamides | 1998 |
Neutrophil elastase contributes to the development of ischemia-reperfusion-induced liver injury by decreasing endothelial production of prostacyclin in rats.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Capillary Permeability; Cephalosporins; Chemokines, CXC; Cyclooxygenase Inhibitors; Endothelium; Enzyme Inhibitors; Epoprostenol; Glycine; Iloprost; Indomethacin; Intercellular Signaling Peptides and Proteins; Leukocyte Elastase; Liver; Liver Circulation; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Peroxidase; Rats; Rats, Wistar; Reperfusion Injury; Sulfonamides; Transaminases; Vasodilator Agents | 2004 |
Role of neutrophil elastase in development of pulmonary vascular injury and septic shock in rats.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Cephalosporins; Endotoxins; Enzyme Inhibitors; Leukocyte Elastase; Lung; Lung Diseases; Male; Nitric Oxide; Rats; Shock, Septic; Tumor Necrosis Factor-alpha; Vascular Diseases | 2008 |
Neutrophil elastase contributes to the development of ischemia/reperfusion-induced liver injury by decreasing the production of insulin-like growth factor-I in rats.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Calcitonin Gene-Related Peptide; Cephalosporins; Glycine; Hepatic Artery; Iloprost; Indomethacin; Insulin-Like Growth Factor I; Leukocyte Elastase; Liver; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type II; Peroxidase; Platelet Aggregation Inhibitors; Portal Vein; Rats; Rats, Wistar; Reperfusion Injury; Serine Proteinase Inhibitors; Sulfonamides | 2010 |