Page last updated: 2024-08-24

cephalosporin c and deacetoxycephalosporin c

cephalosporin c has been researched along with deacetoxycephalosporin c in 25 studies

Research

Studies (25)

TimeframeStudies, this research(%)All Research%
pre-199010 (40.00)18.7374
1990's4 (16.00)18.2507
2000's6 (24.00)29.6817
2010's2 (8.00)24.3611
2020's3 (12.00)2.80

Authors

AuthorsStudies
Abraham, EP; Beckmann, R; Cantwell, C; Queener, SW; Whiteman, P1
Fernandez, FJ; Gutiérrez, S; Martín, JF; Velasco, J1
Dotzlaf, JE; Yeh, WK1
Demain, AL; Jensen, SE; Shen, YQ; Westlake, DW; Wolfe, S1
Fox, M; White, ER1
Küenzi, MT; Nüesch, J; Scheidegger, A1
Bowers, RJ; Jensen, SE; Lyubechansky, L; Westlake, DW; Wolfe, S1
Jensen, SE; Westlake, DW; Wolfe, S1
Principe, PA; Ricca, CM; Singh, PD; Sykes, RB; Trejo, WH; Ward, PC; Wells, JS1
Baldwin, JE; Demain, AL; Sawada, Y; Singh, PD; Yoshida, M1
Baldwin, JE; Keeping, JW; Singh, PD; Vallejo, CA1
Alvi, KA; Lein, J; Peterson, J; Reeves, CD1
Adrio, JL; Cho, H; Demain, AL; Hintermann, G; Luengo, JM; Ocran, S; Piret, JM; Wolfe, S1
Baldwin, JE; Clifton, IJ; Harlos, K; Lee, HJ; Lloyd, MD; Schofield, CJ1
Baldwin, JE; Dubus, A; Frere, JM; Lee, HJ; Lloyd, MD; Schofield, CJ1
Hsu, JS; Liu, WC; Tsai, YC; Wang, WC; Wei, CL; Yang, YB1
Chin, HS; Goo, KS; Sim, TS1
Baldwin, JE; Hensgens, CM; Hewitson, KS; Lipscomb, SJ; Lloyd, MD; Schofield, CJ1
Abian, O; Fernández-Lafuente, R; Guisán, JM; Illanes, A; Pessela, BC; Wilson, L1
Capone, JJ; Nagarajan, R; Queener, SW; Radue, AB1
An, Y; Dong, H; Liu, G1
Fan, K; Lin, B; Tao, Y; Yang, K1
Liu, Y; Shi, J1
Wang, J; Yang, G1
Chen, R; Gao, S; Jiang, Y; Li, J; Liang, W; Qu, G; Song, S; Su, W; Sun, Z; Yang, D; Yuan, B; Zhang, W1

Reviews

1 review(s) available for cephalosporin c and deacetoxycephalosporin c

ArticleYear
Engineering deacetoxycephalosporin C synthase as a catalyst for the bioconversion of penicillins.
    Journal of industrial microbiology & biotechnology, 2017, Volume: 44, Issue:4-5

    Topics: Biocatalysis; Cephalosporins; Escherichia coli; Penicillin G; Penicillins; Substrate Specificity

2017

Other Studies

24 other study(ies) available for cephalosporin c and deacetoxycephalosporin c

ArticleYear
Isolation of deacetoxycephalosporin C from fermentation broths of Penicillium chrysogenum transformants: construction of a new fungal biosynthetic pathway.
    Proceedings. Biological sciences, 1992, Jun-22, Volume: 248, Issue:1323

    Topics: Amino Acid Isomerases; Bacterial Proteins; Cephalosporins; DNA, Fungal; Fermentation; Genetic Vectors; Intramolecular Transferases; Isomerases; Penicillin-Binding Proteins; Penicillium chrysogenum; Streptomyces; Transformation, Genetic

1992
The cefG gene of Cephalosporium acremonium is linked to the cefEF gene and encodes a deacetylcephalosporin C acetyltransferase closely related to homoserine O-acetyltransferase.
    Journal of bacteriology, 1992, Volume: 174, Issue:9

    Topics: Acetyltransferases; Acremonium; Amino Acid Sequence; Base Sequence; Cephalosporins; Chromosome Mapping; Genetic Complementation Test; Intramolecular Transferases; Introns; Isomerases; Molecular Sequence Data; Oxygenases; Penicillin-Binding Proteins; Penicillium chrysogenum; Sequence Homology, Nucleic Acid; Transcription, Genetic

1992
Copurification and characterization of deacetoxycephalosporin C synthetase/hydroxylase from Cephalosporium acremonium.
    Journal of bacteriology, 1987, Volume: 169, Issue:4

    Topics: Acremonium; Amino Acids; Cephalosporins; Chelating Agents; Hydrogen-Ion Concentration; Intramolecular Transferases; Isoelectric Point; Isomerases; Metals; Molecular Weight; Oxygenases; Penicillin-Binding Proteins; Penicillins; Substrate Specificity; Sulfhydryl Reagents; Temperature

1987
Further studies on the cyclization of the unnatural tripeptide delta-(D-alpha-aminoadipyl)-L-cysteinyl-D-valine to penicillin N.
    The Journal of antibiotics, 1986, Volume: 39, Issue:7

    Topics: Cephalosporins; Cyclization; Oligopeptides; Penicillins; Streptomyces

1986
Custom made C18 columns for the hydrophobic chromatography of cephalosporin C derivatives.
    The Journal of antibiotics, 1982, Volume: 35, Issue:11

    Topics: Cephalosporins; Chromatography, High Pressure Liquid; Silicon Dioxide

1982
Partial purification and catalytic properties of a bifunctional enzyme in the biosynthetic pathway of beta-lactams in Cephalosporium acremonium.
    The Journal of antibiotics, 1984, Volume: 37, Issue:5

    Topics: Acremonium; Adenosine Triphosphate; Cephalosporins; Intramolecular Transferases; Isomerases; Mixed Function Oxygenases; Penicillin-Binding Proteins

1984
Enzymatic synthesis of the penicillin and cephalosporin nuclei from an acyclic peptide containing carboxymethylcysteine.
    Biochemical and biophysical research communications, 1984, Apr-30, Volume: 120, Issue:2

    Topics: Amino Acid Isomerases; Bacterial Proteins; Biological Assay; Cephalosporins; Chemical Phenomena; Chemistry; Chromatography, High Pressure Liquid; Enzymes; Oligopeptides; Oxidoreductases; Penicillins; Streptomyces

1984
Analysis of penicillin N ring expansion activity from Streptomyces clavuligerus by ion-pair high-pressure liquid chromatography.
    Antimicrobial agents and chemotherapy, 1983, Volume: 24, Issue:3

    Topics: Cephalosporins; Chemical Phenomena; Chemistry; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Culture Media; Penicillins; Spectrophotometry, Ultraviolet; Streptomyces

1983
Bacterial production of deacetoxycephalosporin C.
    The Journal of antibiotics, 1982, Volume: 35, Issue:10

    Topics: Bacteria; Cephalosporins; Fermentation; Flavobacterium; Mass Spectrometry; Xanthomonas

1982
Incorporation of 3H and 14C from (6 alpha-3H)penicillin N and (10-14C,6 alpha-3H) penicillin N into deacetoxycephalosporin C.
    The Biochemical journal, 1980, Mar-15, Volume: 186, Issue:3

    Topics: Acremonium; Ascorbic Acid; Carbon Radioisotopes; Cephalosporins; Chemical Phenomena; Chemistry; Chromatography, High Pressure Liquid; Ferrous Compounds; Penicillins; Tritium

1980
Cell-free conversion of isopenicillin N into deacetoxycephalosporin C by Cephalosporium acremonium mutant M-0198.
    The Biochemical journal, 1981, Feb-15, Volume: 194, Issue:2

    Topics: Acremonium; Cephalosporins; Chromatography, High Pressure Liquid; Penicillins

1981
Isolation and identification of a new cephem compound from Penicillium chrysogenum strains expressing deacetoxycephalosporin C synthase activity.
    The Journal of antibiotics, 1995, Volume: 48, Issue:4

    Topics: Cephalosporins; Chemical Phenomena; Chemistry, Physical; Chromatography, High Pressure Liquid; Intramolecular Transferases; Isomerases; Magnetic Resonance Spectroscopy; Mass Spectrometry; Molecular Structure; Penicillin-Binding Proteins; Penicillium chrysogenum; Spectrophotometry, Ultraviolet

1995
Elucidation of conditions allowing conversion of penicillin G and other penicillins to deacetoxycephalosporins by resting cells and extracts of Streptomyces clavuligerus NP1.
    Proceedings of the National Academy of Sciences of the United States of America, 1998, Sep-29, Volume: 95, Issue:20

    Topics: Adenosine Triphosphate; Ascorbic Acid; Cephalosporins; Colony Count, Microbial; Dithiothreitol; Ferrous Compounds; Interphase; Intramolecular Transferases; Ketoglutaric Acids; Kinetics; Magnesium Sulfate; Penicillin G; Penicillin-Binding Proteins; Penicillins; Potassium Chloride; Streptomyces

1998
Kinetic and crystallographic studies on deacetoxycephalosporin C synthase (DAOCS).
    Journal of molecular biology, 2001, May-18, Volume: 308, Issue:5

    Topics: Amino Acid Sequence; Carbon Dioxide; Cephalosporins; Crystallization; Crystallography, X-Ray; Intramolecular Transferases; Iron; Ketoglutaric Acids; Kinetics; Models, Molecular; Molecular Sequence Data; Penicillin-Binding Proteins; Penicillins; Protein Engineering; Protein Structure, Quaternary; Sequence Deletion; Streptomyces; Succinic Acid

2001
Probing the penicillin sidechain selectivity of recombinant deacetoxycephalosporin C synthase.
    Cellular and molecular life sciences : CMLS, 2001, Volume: 58, Issue:5-6

    Topics: Amoxicillin; Ampicillin; Ascorbic Acid; Carbon Dioxide; Cephalexin; Cephalosporins; Chromatography, High Pressure Liquid; Coenzymes; Intramolecular Transferases; Iron; Ketoglutaric Acids; Kinetics; Oxygen; Penicillin G; Penicillin V; Penicillin-Binding Proteins; Penicillins; Recombinant Proteins; Reducing Agents; Spectrophotometry; Streptomyces; Substrate Specificity; Thermodynamics

2001
Engineering Streptomyces clavuligerus deacetoxycephalosporin C synthase for optimal ring expansion activity toward penicillin G.
    Applied and environmental microbiology, 2003, Volume: 69, Issue:4

    Topics: Amino Acid Substitution; Cephalosporins; Chromatography, High Pressure Liquid; Genetic Engineering; Industrial Microbiology; Models, Molecular; Mutagenesis, Site-Directed; Penicillin G; Streptomyces

2003
A complete library of amino acid alterations at N304 in Streptomyces clavuligerus deacetoxycephalosporin C synthase elucidates the basis for enhanced penicillin analogue conversion.
    Applied and environmental microbiology, 2004, Volume: 70, Issue:1

    Topics: Amino Acid Substitution; Cephalosporins; Intramolecular Transferases; Penicillin-Binding Proteins; Penicillins; Streptomyces

2004
Controlling the substrate selectivity of deacetoxycephalosporin/deacetylcephalosporin C synthase.
    The Journal of biological chemistry, 2004, Apr-09, Volume: 279, Issue:15

    Topics: Acremonium; Amino Acid Sequence; Asparagine; Binding Sites; Cephalosporins; Cloning, Molecular; Intramolecular Transferases; Iron; Kinetics; Methionine; Models, Chemical; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Oxygen; Oxygenases; Penicillin-Binding Proteins; Penicillins; Point Mutation; Protein Binding; Protein Structure, Tertiary; Sequence Homology, Amino Acid; Streptomyces; Substrate Specificity; Tryptophan

2004
Encapsulation of crosslinked penicillin G acylase aggregates in lentikats: evaluation of a novel biocatalyst in organic media.
    Biotechnology and bioengineering, 2004, Jun-05, Volume: 86, Issue:5

    Topics: Absorption; Catalysis; Cephalosporins; Cross-Linking Reagents; Dimerization; Enzyme Activation; Enzyme Stability; Enzymes, Immobilized; Hydrogels; Hydrolysis; Organic Chemicals; Penicillin Amidase; Polyvinyl Alcohol; Temperature

2004
Synthesis of deactoxycephalosporin C by a mutant of Cephalosporium acremonium.
    Antimicrobial agents and chemotherapy, 1974, Volume: 6, Issue:3

    Topics: Acremonium; Cephalosporins; Mutation

1974
Expression of cefF significantly decreased deacetoxycephalosporin C formation during cephalosporin C production in Acremonium chrysogenum.
    Journal of industrial microbiology & biotechnology, 2012, Volume: 39, Issue:2

    Topics: Acremonium; Agrobacterium; Biotechnology; Cephalosporins; Fermentation; Genes, Fungal; Oxygenases; Penicillins; Streptomyces

2012
Mechanistic Insights into the Oxidative Ring Expansion from Penicillin N to Deacetoxycephalosporin C Catalyzed by a Nonheme Iron(II) and α-KG-Dependent Oxygenase.
    Inorganic chemistry, 2020, Sep-08, Volume: 59, Issue:17

    Topics: Biocatalysis; Catalysis; Cephalosporins; Iron; Models, Molecular; Molecular Conformation; Oxidation-Reduction; Oxygenases; Penicillins; Quantum Theory

2020
Enhanced antibiotic degradation and hydrogen production of deacetoxycephalosporin C fermentation residue by gamma radiation coupled with nano zero-valent iron.
    Journal of hazardous materials, 2022, Feb-15, Volume: 424, Issue:Pt B

    Topics: Anti-Bacterial Agents; Cephalosporins; Fermentation; Gamma Rays; Hydrogen; Iron

2022
Whole-Cell Biotransformation of Penicillin G by a Three-Enzyme Co-expression System with Engineered Deacetoxycephalosporin C Synthase.
    Chembiochem : a European journal of chemical biology, 2022, 06-03, Volume: 23, Issue:11

    Topics: Biotransformation; Cephalosporins; Escherichia coli; Intramolecular Transferases; Penicillin G; Penicillin-Binding Proteins

2022