cephalosporin c has been researched along with cefepime in 1170 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 43 (3.68) | 18.7374 |
| 1990's | 251 (21.45) | 18.2507 |
| 2000's | 442 (37.78) | 29.6817 |
| 2010's | 381 (32.56) | 24.3611 |
| 2020's | 53 (4.53) | 2.80 |
| Authors | Studies |
|---|---|
| Girlich, D; Leclercq, R; Naas, T; Nordmann, P | 1 |
| Anderson, KC; Kellogg, GE; Sarkar, A | 1 |
| Conejo, MC; Pascual, A; Perea, EJ; Suárez, AI | 1 |
| Jones, RN | 2 |
| Appleman, MD; Berne, TV; Chin, A; Gill, MA; Heseltine, PN; Knupp, CA; Nakahiro, RK; Okamoto, MP; Sclar, DA; Yellin, AE | 1 |
| Barbhaiya, RH; Knupp, CA; Pittman, KA | 1 |
| Fukuhara, H; Hiraga, Y; Irabu, Y; Nakayama, I; Ohmichi, M; Oizumi, K; Saito, A; Shigeno, Y; Watanabe, A | 1 |
| Fujita, Y; Fukuhara, H; Hashizume, H; Irabu, Y; Nakano, H; Onodera, S; Saito, A; Sasaki, N; Shigeno, Y; Shimizu, T | 1 |
| Fukuhara, H; Inatome, J; Irabu, Y; Miyakuni, T; Nakano, H; Ohshiro, H; Onodera, S; Saito, A; Shigeno, Y; Shimizu, T | 1 |
| Esumi, Y; Nakanomyo, H; Ninomiya, S; Okamura, Y; Seki, H; Sudo, Y; Takaichi, M | 2 |
| Bächer, K; Borner, K; Koeppe, P; Lode, H; Nord, CE; Schaeffer, M | 1 |
| Hannecart-Pokorni, E; Nulens, E; Nyssen, HJ; Vanhoof, R | 1 |
| Cronqvist, J; Nilsson-Ehle, I; Norrby, SR; Oqvist, B | 1 |
| Bailey, EM; Lamp, KC; McGrath, BJ; Rybak, MJ | 1 |
| Mattie, H; Sekh, BA; van Ogtrop, ML; van Strijen, E | 1 |
| Hiruma, R; Katsu, K; Watanabe, N | 1 |
| Donnelly, JP | 1 |
| Arguedas, AG; Knupp, CA; Marks, MI; Nussbaum, E; Stutman, HR; Zaleska, M | 1 |
| Chikazawa, H; Funahashi, N; Ishikawa, K; Kadota, T; Kawano, S; Kondoh, H; Kuroyanagi, K; Sakakura, K; Shimizu, N; Takahashi, N | 1 |
| Chikazawa, H; Hattori, N; Hiraiwa, E; Kadota, T; Kai, S; Kawano, S; Kohmura, H; Kondoh, H; Kuroyanagi, K; Sakakura, K | 1 |
| Ishikawa, K; Kadota, T; Kai, S; Kawano, S; Kohmura, H; Kuroyanagi, K; Sakai, A; Takahashi, N | 1 |
| Amano, M; Goto, A; Hara, M; Sakai, A; Takahashi, N | 1 |
| Barbhaiya, RH; Knupp, CA; Pfeffer, M; Pittman, KA | 1 |
| Barbhaiya, RH; Dukes, GM; Hak, LJ; Knupp, CA; Mattern, W; Pfeffer, M; Pittman, KA; Zaccardelli, D | 1 |
| Barriere, SL; Johnson, BL; Kalman, D | 1 |
| Andrews, JM; Arkell, D; Ashrap, M; Wise, R | 1 |
| Jin, C | 1 |
| Barbhaiya, RH; Forgue, ST; Gleason, CR; Knupp, CA; Martin, RR; Movahhed, H; Pittman, KA; Tenney, J; Weidler, DJ | 1 |
| Pechère, JC; Vladoianu, IR | 1 |
| Barbhaiya, RH; Knupp, CA; Papp, EA | 1 |
| Blake, J; Cassiano-Clough, L; Cosand, WL; Cunningham, MD; Darveau, RP; Maloney, G; Seachord, CL | 1 |
| Brown, MP; Castro, L; Gronwall, RR; Stampley, AR; Stone, HW | 1 |
| Appleman, MD; Berne, TV; Chin, A; Gill, MA; Heseltine, PN; Knupp, CA; Okamoto, MP; Sclar, DA; Yellin, AE | 1 |
| Aiken, S; Cassano, K; Chirurgi, V; Edelstein, H; Karp, R; McCabe, R; Oster, S | 1 |
| Griggs, DJ; Piddock, LJ | 1 |
| Hanberger, H; Maller, R; Nilsson, LE; Nilsson, M | 1 |
| Boice-Sowek, J; Dougherty, TJ; Kessler, RE; Pucci, MJ | 1 |
| Gentry, LO; Rodriguez-Gomez, G | 1 |
| Fung-Tomc, J; Huczko, E; Kessler, RE; Kolek, B; Thater, C | 1 |
| Barbhaiya, RH; Brindley, CJ; Brodie, RR; Chasseaud, LF; Cook, SC; Oldfield, PR | 1 |
| Guiot, HF; Mattie, H; van Furth, R; van Ogtrop, ML | 1 |
| Fujimoto, M; Kinoshita, H; Morimoto, K; Morimoto, Y; Nakatani, S; Ohmori, K; Ohno, K; Sakai, K; Ueda, T | 1 |
| Bosso, JA; Matsen, JM; Saxon, BA | 1 |
| Blake, J; Cassiano-Clough, L; Cosand, WL; Cunningham, MD; Darveau, RP; Seachord, CL; Watkins, CS | 1 |
| Kovarik, J; Rozenberg-Arska, M; Verhoef, J; Visser, M | 1 |
| Cunningham, MD; Darveau, RP | 1 |
| Dornbusch, K; Göransson, E; Mörtsell, E | 1 |
| Andrews, JM; Ashby, JP; Baldwin, DR; Chadha, D; Honeybourne, D; Wise, R | 1 |
| Barbhaiya, RH; Forgue, ST; Gleason, CR; Knupp, CA; Martin, RR; Pittman, KA; Weidler, DJ | 1 |
| Cassano, K; Edelstein, H; McCabe, R; Oster, S | 1 |
| Boothman, C; King, A; Phillips, I | 1 |
| Barbhaiya, RH; Knupp, CA; Martin, RR; Pittman, KA; Tenney, J; Weidler, DJ | 1 |
| Gill, EA; Norden, CW | 1 |
| Deenstra, M; Hart, HC; Hoepelman, IM; Kovarik, JM; Matzke, GR; Rademaker, CM; ter Maaten, JC; Verhoef, J | 1 |
| Guiot, HF; Hazekamp-van Dokkum, AM; Mattie, H; van Furth, R; van Ogtrop, ML; van Strijen, E | 1 |
| Bies, M; Kessler, RE; Leitner, F; Tsai, YH | 1 |
| Barbhaiya, RH; Forgue, ST; Guay, DR; Knupp, CA; Matzke, GR; Pittman, KA | 1 |
| DeOrio, FJ; Dougherty, TJ; Fung-Tomc, J; Kessler, RE; Simich-Jacobson, V | 1 |
| Daschner, F; Kropec, A | 1 |
| Avlamis, A; Giamarellou, H; Mavroudis, T; Voutsinas, D | 1 |
| Knapp, CC; Washington, JA | 1 |
| Hirano, M; Hiraoka, M; Inoue, M; Masuyoshi, S; Mitsuhashi, S; Tomatsu, K | 1 |
| Fuchs, PC; Jones, RN | 1 |
| Hoepelman, IM; Keller, N; Raponi, G; Rozenberg-Arska, M; Verhoef, J | 1 |
| Beumer, H; Hoepelman, IM; Rozenberg-Arska, M; Verhoef, J; Visser, MR | 1 |
| Andrews, JM; Nye, KJ; Shi, YG; Wise, R | 1 |
| Darouiche, R; Hamill, R; Musher, D; Ou, C; Rognerud, C | 1 |
| Ingerman, MJ; Levison, ME; Pitsakis, PG; Rosenberg, AF | 1 |
| Boelaert, J; Gordts, B; Lambert, A; Van Landuyt, HW | 1 |
| Neiderriter, K; Norden, CW | 1 |
| Fung-Tomc, J; Huczko, E; Kessler, RE; Pearce, M | 1 |
| Chin, NX; Neu, HC; Novelli, A | 1 |
| Jay, WM; Shockley, RK | 1 |
| Hiraoka, M; Inoue, M; Masuyoshi, S; Mitsuhashi, S; Tomatsu, K | 1 |
| Alvarez, ME; Bodey, GP; Hsu, KC; Rolston, KV | 1 |
| Cynamon, MH; Palmer, GS; Sorg, TB | 1 |
| Durgham, SM; Ishag, AJ; Shibl, AM | 1 |
| Chin, NX; Jules, K; Labthavikul, P; Neu, HC | 1 |
| Carlton, DD; Farrell, CA; Kessler, RE; Phelps, DJ | 1 |
| Ayers, LW; Barry, AL; Fuchs, PC; Gavan, TL; Gerlach, EH; Jones, RN | 1 |
| Ando, S; Hirano, M; Kawaguchi, H; Masuyoshi, S; Miyaki, T; Tomatsu, K | 1 |
| Barbhaiya, RH; Forgue, ST; Papp, EA; Pittman, KA; Shyu, WC | 1 |
| Lucain, C; Marchou, B; Michea-Hamzehpour, M; Pechère, JC | 1 |
| Barbhaiya, RH; Forgue, ST; Gleason, CR; Pittman, KA; Shyu, WC | 1 |
| Chryssouli, Z; Giamarellou, H; Sahin, A | 1 |
| Barry, AL; Fuchs, PC; Jones, RN; Thornsberry, C | 2 |
| Aburaki, S; Kamachi, H; Kawaguchi, H; Naito, T; Narita, Y; Okumura, J | 1 |
| Bodey, GP; Ho, DH; LeBlanc, B | 1 |
| Hackbarth, CJ; Rusnak, MG; Sande, MA; Scott, KG; Täuber, MG | 1 |
| Barry, AL; Jones, RN; Packer, RR | 1 |
| Clarke, AM; Wright, JM; Zemcov, SJ | 1 |
| Bertram, MA; Maniatis, A; Tsuji, A; Young, LS | 1 |
| Edwards, BH; Rissing, JP; Steele, JC | 1 |
| Pijck, J; Vuye, A | 1 |
| Bies, M; Buck, RE; Chisholm, DR; Kessler, RE; Leitner, F; Misiek, M; Price, KE; Pursiano, TA; Tsai, YH | 1 |
| Buxton, TB; Rissing, JP; Shockley, RK; Yannis, RA | 1 |
| Bayer, AS; Kim, KS | 1 |
| Conrad, DA; Marks, MI; Scribner, RK; Weber, AH | 1 |
| Bihl, JA; Khan, NJ; LeFrock, JL; Schell, RF; Weber, SJ | 1 |
| Barradell, LB; Bryson, HM | 1 |
| Gold, MJ; Johnson, CC; Levison, ME; Livornese, L; Pitsakis, PG; Taylor, S | 1 |
| Cony Makhoul, P; Darmaillac, V; Fourche, J; Maugein, J; Perrier, F | 1 |
| Baquero, F; Cantón, R; García de Lomas, J; Gimeno, C; Liñares, J; Martínez-Beltrán, J; Tubau, F | 1 |
| Kelly, JW; McAllister, CK; Schrank, JH | 1 |
| Harris, EB; Hastings, RC; Prabhakaran, K; Randhawa, B | 1 |
| Hof, H | 1 |
| Báez, C; Castaño, E; García, R; McCracken, GH; Pérez, M; Sáez-Llorens, X; Tejeira, F | 1 |
| Cunha, BA; Gill, MV | 1 |
| Cheng, DL; Huang, WK; Liu, YC | 1 |
| Baltch, AL; Ritz, W; Smith, RP | 1 |
| Barriga, C; Ortega, E; Pedrera, MI; Rodríguez, AB | 1 |
| Frei, R; Hoban, DJ; Jones, RN; Marco, F; Pignatari, AC; Yamane, N | 1 |
| Jones, RN; Marshall, SA | 1 |
| Palmer, SM; Rybak, MJ | 1 |
| Bedikian, A; Chin, A; Gill, MA; Nakahiro, RK; Okamoto, MP | 1 |
| Woods, M | 1 |
| Acar, J; Bergan, T; Degener, J; Phillips, I; Schito, GC | 1 |
| Carrabba, I; Cavallaro, V; Cocuzza, C; Di Marco, R; Franco, S; Nicoletti, F; Nicoletti, G; Stazzone, C; Zaccone, P | 1 |
| Barbhaiya, RH; Chasseaud, LF; Jordan, MC; Waller, AR | 1 |
| Santella, PJ; Van der Auwera, P | 1 |
| Branger, JM; Hoepelman, AI; Kieft, H; Knupp, CA; Struyvenberg, A; van Dijk, A; Verhoef, J | 1 |
| Giamarellou, H | 2 |
| Bouchillon, SK; Brown, SD; Marler, JK; Rich, T; Thornsberry, C; Yee, YC | 2 |
| Bertrand, A; Chidiac, C; Dellamonica, P; Humbert, G; Leroy, J; Micoud, M; Modai, J; Mouton, Y; Stahl, JP; Veyssier, P | 1 |
| Hageage, G; Jauregui, L; Matzke, D; Minns, P; Scott, M | 1 |
| Aoun, M; Calandra, T; Eggimann, P; Glauser, MP; Meunier, F | 1 |
| Bertrand, A; Delaval, P; Depierre, A; Grès, JJ; Hughes, F; Léophonte, P; Lucht, F; Muir, JF; Nouvet, G; Ulmer, M | 1 |
| Aoun, M; Gillespie, SH; Hoepelman, AI; Kieft, H; Kosmidis, J; Meunier, F; Riddell, J; Strand, T; Varghese, G; Verhoef, J | 1 |
| Barckow, D; Schwigon, CD | 1 |
| Hemsell, DL; Newton, ER; Pastorek, JG; Soper, DE; Yeomans, ER | 1 |
| Albanese, J; Domart, Y; Durbec, O; Gouin, F; Grès, JJ; Leroy, J; Martin, C; Papazian, L; Rollin, C; Veyssier, P | 1 |
| Chong, Y; Kwon, OH; Lee, K | 1 |
| Acar, JF; Bergogne-Bérézin, E; Cluzel, R; Courvalin, P; Duval, J; Grès, JJ; Rollin, C; Soussy, CJ; Thabaut, A | 1 |
| Chen, HY; Livermore, DM | 2 |
| Low, DE; Scriver, SR; Toye, BW | 1 |
| Grassi, C; Grassi, GG | 1 |
| Desiderio, JV; Hibbard, JR; Lamb, LM; Tsai, YH | 1 |
| Branger, JM; Geers, AB; Hart, HC; Hoepelman, AI; Kieft, H; Kluyver, M; Poest-Clement, E; Rozenberg-Arska, M; van Beugen, L; Voskuil, JH | 1 |
| Allen, SD; Gerlach, EH; Jones, RN; Knapp, CC; Murray, PR; Washington, JA | 1 |
| Sanders, CC | 1 |
| Khoosal, M; Klugman, KP; Saunders, J | 1 |
| Appleman, MD; Berne, TV; Gill, MA; Heseltine, PN; Yellin, AE | 1 |
| Appleman, MD; Baker, FJ; Berne, TV; Gill, MA; Heseltine, PN; Holcomb, C; Okamoto, MP; Yellin, AE | 1 |
| Bennion, RS; Hopkins, JA; Lally, KP; Roettger, R; Thompson, JE; Wilson, SE | 1 |
| Halijah, MY; Lim, VK | 1 |
| Bonner, DP; Fung-Tomc, J; Kolek, B | 1 |
| Bosso, JA; Huls, CE; Prince, RA; Seilheimer, DK | 1 |
| Bedikian, A; Chin, A; Nakahiro, RK; Okamoto, MP | 1 |
| Bale, MJ; Jones, RN | 1 |
| Barza, M; Baum, JL; Lynch, E | 1 |
| Bedikian, A; Berne, TV; Chin, A; Gill, MA; Knupp, CA; Nakahiro, RK; Okamoto, MP; Yellin, AE | 1 |
| Garcia-Villanova, J; Gómez, MD; Parra, A; Ródenas, V | 1 |
| Deguchi, K; Fukayama, S; Fukumoto, T; Ishihara, R; Koguchi, M; Nakane, Y; Oda, S; Suzuki, Y; Tanaka, S | 1 |
| Glupczynski, Y; Verbist, L | 1 |
| Rybak, M | 1 |
| Levin, S; Segreti, J | 1 |
| Holloway, WJ; Palmer, D | 1 |
| Chirurgi, V; Farkas, SA; Greene, S; Haddow, A; Heinz, G; McCabe, R | 1 |
| Neu, HC | 1 |
| Childs, S; Geckler, R; Sharifi, R | 1 |
| Cimino, M; Gucalp, R; Oblon, D; Ramphal, R; Rotstein, C | 1 |
| Das-Young, LR; Frank, E; Ramirez-Ronda, C; Schwartz, R | 1 |
| Bonner, DP; Dougherty, TJ; Fung-Tomc, JC; Gradelski, E; Huczko, E; Kessler, RE | 1 |
| Laws, A; Page, M | 1 |
| Wise, R | 1 |
| Modai, J | 1 |
| Shah, PM | 1 |
| Boucaud-Maître, Y; Thoinet, S | 1 |
| Elkhaïli, H; Jehl, F; Kamili, N; Linger, L; Monteil, H; Pompei, D | 1 |
| Cavalier, A; Elkhaïli, H; Jehl, F; Kaltenbach, G; Levêque, D; Monteil, H; Peter, JD; Salmon, J; Salmon, Y | 1 |
| Pechère, JC | 1 |
| Devalckenaere, A; Husson, MO; Izard, D; Vachée, A | 1 |
| Dopff, C; Gérard, A; Le Meins, V; Maurer, P; Witz, B | 1 |
| Ette, EI; Ludden, TM | 1 |
| Abumustafa, F; Cunha, BA; Domenico, P; Imambaccus, H; Qadri, SM; Tullo, DD; Ueno, Y | 1 |
| McDonald, PJ; Pruul, H | 1 |
| Bosso, JA; Burgess, DS; Manduru, M; White, RL | 1 |
| Kessler, RE; Sanders, WE; Tenney, JH | 1 |
| Bugay, DE; Findlay, WP; Newman, AW | 1 |
| Garcia, Y; Gomez-Lus, ML; Herrera, I; Martinez, P; Perez, P; Prieto, J | 1 |
| Hara, K | 1 |
| Goossens, H; Stes, P | 1 |
| Paladino, JA; Wynd, MA | 1 |
| Cordonnier, C; Delain, M; Delmer, A; Gardembas, M; Gres, JJ; Herbrecht, R; Ladeb, S; Moreau, P; Nalet, V; Pico, JL; Rollin, C | 1 |
| Caillon, J; Jacolot, A; Louchahi, K; Mimoz, O; Padoin, C; Petitjean, O; Samii, K; Tod, M | 1 |
| Mandell, GL; Townsend, GC | 1 |
| Blahová, J; Králiková, K; Krcméry, V; Kubonová, K | 1 |
| Elkhaïli, H; Jehl, F; Linger, L; Monteil, H | 1 |
| Eliopoulos, GM; Moellering, RC; Thauvin-Eliopoulos, C; Tripodi, MF | 1 |
| Ambrose, PG; Owens, RC; Quintiliani, R | 1 |
| Aufiero, A; Goglio, A; La Regina, A; Marruchella, A; Michetti, G; Nicolin, E; Sella, D; Silleni, M; Sturani, C; Zanon, P | 1 |
| Blahová, J; Hupková-Lesická, M; Králiková, K; Krcméry, V; Kubonová, K | 1 |
| Magalhães, M; Mendes, CM; Mimiça, I; Montelli, AC; Nowakonski, A; Rossi, F; Sader, HS; Sampaio, JL; Segura, AJ; Zoccoli, C | 1 |
| Carlisle, P; Cimino, M; Gucalp, R; Roberts, J; Rotstein, C; Yamamura, D | 1 |
| Blumer, JL; Knupp, CK; Reed, MD; Veazey, JM; Yamashita, TS | 1 |
| Ashhurst-Smith, C; Norton, R; Seymour-Murray, J | 1 |
| Descheemaeker, P; Goossens, H; Ieven, M; Sanders, CC; Vercauteren, E | 1 |
| Abate, G; Hoffner, SE | 1 |
| Elkhaïli, H; Jehl, F; Levêque, D; Linger, L; Monteil, H; Niedergang, S; Peter, JD; Pompei, D; Salmon, J; Salmon, Y; Thierry, RC | 1 |
| Abinasr, A; Bebear, C; Bezian, MC; el Harrif, Z; Melon, M; Quentin, C; Rougier, C; Tessier, F; Texier-Maugein, J | 1 |
| Allouch, PY; Chaplain, C; Godard, T; Lorin de Reure, V; Pina, P; Simon, B | 1 |
| Black, D; Fritsche, TR; Gautom, RK; Limaye, AP | 1 |
| Medeiros, AA | 1 |
| Allaouchiche, B; Breilh, D; Gaillard, B; Jaumain, H; Renard, S; Saux, MC | 1 |
| Kontodimou, L; Malaka, E; Polydorou, F; Sofianou, D; Tsoulfa, S | 1 |
| Dahlgren, AF | 1 |
| Ho, SW; Hsueh, PR; Luh, KT; Teng, LJ; Yang, PC | 1 |
| Barie, PS; Baumgartner, TF; Dellinger, EP; Rotstein, OD; Solomkin, JS; Vogel, SB; Yang, JY | 1 |
| Espersen, F; Frimodt-Møller, N; Fuursted, K; Knudsen, JD | 1 |
| Gazouli, M; Giakkoupi, P; Katrahoura, A; Legakis, NJ; Paniara, O; Prinarakis, E; Tzelepi, E; Tzouvelekis, LS | 1 |
| Klastersky, J | 1 |
| Doern, GV; Jones, RN; Pfaller, MA; Salazar, JC | 1 |
| Jones, RN; Marshall, SA; Pfaller, MA | 1 |
| Mulin, B; Talon, D; Thouverez, M | 1 |
| Chen, YS; Jones, RN; Marshall, SA; Pfaller, MA; Wilke, WW | 1 |
| Friedland, IR; Lutsar, I | 1 |
| Nelson, M; Zervos, M | 1 |
| Clarke, CR; Clarke, JM; Guglick, MA; Hague, C; MacAllister, CG; Pollet, R | 1 |
| Jacolot, A; Mimoz, O; Padoin, C; Petitjean, O; Samii, K; Tod, M | 1 |
| Verbist, L; Verhaegen, J | 1 |
| Emmerechts, K; Lauwers, S; Piérard, D | 1 |
| Escande, MC; Herbrecht, R | 1 |
| Garau, J | 1 |
| Van haute, I; Verschraegen, G | 1 |
| Acar, J | 1 |
| Arai, C; Suzuki, T | 1 |
| Lister, PD; Sanders, CC; Sanders, WE | 1 |
| Barberán, J; Campos, A; García, MC; Khorrami, S | 1 |
| Böhme, A; Hoelzer, D; Shah, PM; Stille, W | 1 |
| Ashkenazi, S; Boulesteix, J; De Pril, V; Eskola, J; Fishbach, M; Grès, JJ; Kafetzis, D; Rollin, C; Schaad, UB; Syriopoulou, V | 1 |
| Liu, CY; Liu, IM; Wang, FD | 1 |
| Au, C; Chan, CY; Cheng, AF; Cheung, SW; Ip, M | 1 |
| Akbal, H; Ozturk, R; Saribaş, S; Vahaboglu, H; Yucel, A | 1 |
| Gabriel, V; Garbino, J; Harbarth, S; Lew, D; Pittet, D | 1 |
| Berneman, ZN; Bruyneel, P; Goossens, H; Mebis, J; Meeus, I; Schroyens, W; Sion, JP; Van Droogenbroeck, J | 1 |
| Fruchart, A; Husson, MO; Izard, D | 1 |
| Barberán, J; Ferrádez, A; Gomis, M; Sánchez, B | 1 |
| Biron, P; Cure, H; Fuhrmann, C; Grès, JJ; Lefebvre, D; Rollin, C; Soler-Michel, P; Thyss, A; Viens, P; Viot, M | 1 |
| Arango, A; Mattar, S; Muelle, C; Parodi, R; Pérez, D; Sánchez, L | 1 |
| Biedenbach, DJ; Doern, GV; Jones, RN; Marshall, SA; Pfaller, MA | 1 |
| Chang, SC; Chen, YC; Fang, CT; Hsieh, SM; Hsueh, PR; Hung, CC; Liu, CJ; Sheng, WH | 1 |
| Hidri, N; Jacolot, A; Leotard, S; Mimoz, O; Nordmann, P; Petitjean, O; Samii, K | 1 |
| Cappelletty, DM | 1 |
| Lawrence, C; Nauciel, C; Ronco, E | 1 |
| Borja, J; Jané, F | 1 |
| Asherov, J; Dan, M; Poch, F | 1 |
| Macheras, P; Parissi-Poulou, M; Valassis, IN | 1 |
| Maddox, FC; Stewart, JT; Warren, FW | 2 |
| Fubara, JO; Notari, RE | 1 |
| Beaucaire, G; Holzapfel, L; Le Fur, D; Léophonte, P; Martin, C; Nicolas, MH; Offenstadt, G; Péan, Y; Philippon, A; Renard, S | 1 |
| Biedenbach, DJ; Jones, RN; Marshall, SA | 1 |
| García-Rodríguez, JA | 1 |
| Boulerice, F; Campbell, DA; Dubois, J; Garber, GE; Grossman, RF; Laforge, J; Landis, SJ; McIvor, RA; Murray, G; Rivard, M; Rotstein, C; Saginur, R; Stiver, HG | 1 |
| Chan, WC; Cheng, AF; Li, RC; Ling, JM; Schentag, JJ | 1 |
| Azanza, JR; Calahorra, B; Campanero, MA; Sádaba, B | 1 |
| Andrieu, P; Archambaud, M; Chabanon, G; Cougot, P; Decun, JF; Georges, B; Houin, G; Mazerolles, M; Saivin, S; Suc, C; Virenque, C | 1 |
| Elhelali, N; Jacolot, A; Laurent, F; Léotard, S; Mimoz, O; Nordmann, P; Petitjean, O; Samii, K | 1 |
| Bonfitto, P; De Vietro, T; Lamorgese, V; Malerba, M; Rizzello, L; Scoditti, S; Zuin, R | 1 |
| Björkholm, M; Dornbusch, K; Engervall, P; Kalin, M | 1 |
| Chan, WK; Chan, YH; Li, CS; Wong, KM | 1 |
| Haverstick, DM; Lynch, PL; Rogers, PD; Volles, DF; Williamson, JC | 1 |
| Iakovlev, SV | 1 |
| Lipman, J; Rickard, C; Wallis, SC | 1 |
| Claeys, G; De Baere, T; Peleman, R; Steyaert, S; Vaneechoutte, M; Verschraegen, G | 1 |
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| Du, X; Fu, Y; Ji, S; Jiang, Y; Lv, F; Mu, X; Wei, Z; Yu, Y | 1 |
| Acosta-Gutierrez, S; Bodrenko, I; Ceccarelli, M; Scorciapino, MA | 1 |
| López-Cerero, L; Pascual, Á; Rodríguez-Martínez, JM; Torres, E | 1 |
| Arnold, CJ; Benjamin, DK; Cho, N; Chu, VH; Clark, RH; Ericson, J; Hornik, CP; Smith, PB; Tian, J; Wilson, S | 1 |
| Bethel, CR; Bonomo, RA; Doi, Y; Endimiani, A; Kasraian, S; Pires, J; Sendi, P; Taracila, M; Tinguely, R | 1 |
| Boyd, AS; Di Pentima, MC; Willis, ZI | 1 |
| Chang, CM; Chen, PL; Ko, WC; Lee, CC; Lee, NY; Li, CW; Li, MC | 1 |
| Crandon, JL; Ghazi, IM; Lesho, EP; McGann, P; Nicolau, DP | 1 |
| Herrington, JD; Tran, HX | 1 |
| Bhadoria, AS; Jindal, A; Kumar, M; Maiwall, R; Sarin, SK | 1 |
| Choi, CH; Kim, DH; Kim, HJ; Kim, JM; Koo, SH; Lee, JH; Oh, MH; Park, HS; Son, YJ; Subhadra, B | 1 |
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| Gholipourmalekabadi, M; Hashemi, A; Mozafari, M; Rostami, A; Sameni, M; Zamani, F | 1 |
| Aamir, M; Abrol, P; Punia, H; Sharma, D | 1 |
| Kuti, JL; Lee, BJ; Liu, J; Neely, MN; Nicasio, AM; Nicolau, DP; Rhodes, NJ; Scheetz, MH; Van Wart, S | 1 |
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| Evans, R; Hussain, T; Karino, S; Kaye, KS; Koons, J; Koppula, S; Martin, ET; Murray, KP; Mynatt, RP; Navalkele, B; Nishan, B; Perry, W; Pervaiz, A; Pogue, JM; Rybak, MJ; Salim, M; Shaikh, H; Solanki, S; Tashtoush, N | 1 |
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| Garello, P; Livermore, DM; Mushtaq, S; Vickers, A; Woodford, N | 2 |
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94 review(s) available for cephalosporin c and cefepime
| Article | Year |
|---|---|
Cefepime. A review of its antibacterial activity, pharmacokinetic properties and therapeutic use.
Topics: Aging; Animals; Bacteria; Bacterial Infections; Cefepime; Cephalosporins; Clinical Trials as Topic; Cystic Fibrosis; Drug Administration Schedule; Humans; Microbial Sensitivity Tests; Renal Insufficiency | 1994 |
Cefepime.
Topics: Bacterial Infections; Cefepime; Cephalosporins; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; Microbial Sensitivity Tests | 1995 |
Cefepime: a new fourth-generation cephalosporin.
Topics: Animals; Bacteria; Bacterial Infections; Cefepime; Cephalosporins; Drug Resistance, Microbial; Humans; Microbial Sensitivity Tests | 1994 |
Pharmacokinetics of cefepime: a review.
Topics: Adult; Aged; Biological Availability; Cefepime; Cephalosporins; Half-Life; Humans; Middle Aged | 1993 |
Cefepime: overview of activity in vitro and in vivo.
Topics: Animals; Bacteria; Bacterial Infections; Cefepime; Cephalosporins; Drug Resistance, Microbial; Humans; Rabbits; Rats | 1993 |
Cefepime: the next generation?
Topics: Animals; Bacterial Infections; Cefepime; Cephalosporins; Drug Resistance, Microbial; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; Microbial Sensitivity Tests | 1993 |
Cefepime clinical pharmacokinetics.
Topics: Bacteria; Bacterial Infections; Cefepime; Cephalosporins; Humans | 1993 |
The pharmacokinetic profile of a new generation of parenteral cephalosporin.
Topics: Adult; Aged; Aged, 80 and over; Cefepime; Cephalosporins; Female; Half-Life; Humans; Male; Middle Aged; Time Factors; Tissue Distribution | 1996 |
Bacteriologic and clinical applications of a new extended-spectrum parenteral cephalosporin.
Topics: Bacteria; Cefepime; Cephalosporins; Drug Resistance, Microbial; Humans; Microbial Sensitivity Tests | 1996 |
Safety of cefepime: a new extended-spectrum parenteral cephalosporin.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Cefepime; Ceftazidime; Cephalosporins; Clinical Trials as Topic; Dose-Response Relationship, Drug; Drug Tolerance; Europe; Female; Humans; Male; Middle Aged; North America; Time Factors | 1996 |
The chemistry and structure-activity relationships of C3-quaternary ammonium cephem antibiotics.
Topics: Amines; Cefepime; Cefpirome; Cephalosporins; Microbial Sensitivity Tests; Quaternary Ammonium Compounds; Structure-Activity Relationship | 1996 |
Tissue penetration of the fourth generation parenteral cephalosporins.
Topics: Animals; Body Fluids; Cefepime; Cefpirome; Ceftazidime; Cephalosporins; Humans; Infusions, Parenteral; Tissue Distribution | 1996 |
Diffusion of 3-quaternary ammonium cephem antibiotics into cerebrospinal fluid of patients with bacterial meningitis.
Topics: Animals; Blood-Brain Barrier; Cefepime; Cefpirome; Cephalosporins; Clinical Trials as Topic; Humans; Meningitis, Bacterial; Microbial Sensitivity Tests | 1996 |
Clinical experience with the fourth generation cephalosporins.
Topics: Bacterial Infections; Cefepime; Cefpirome; Cephalosporins; Clinical Trials as Topic; Humans; Respiratory Tract Infections; Urinary Tract Infections | 1996 |
The position of recently developed broad-spectrum cephem antibiotics in bacterial septicemia.
Topics: Bacteremia; Bacteria; Bacterial Infections; Cefepime; Cefpirome; Cephalosporins; Clinical Trials as Topic; Humans; In Vitro Techniques; Microbial Sensitivity Tests | 1996 |
[Specificities of antibacterial activity of zwitterionic 7-methoxyimino cephems (cephalosporins of fourth generation].
Topics: Cefepime; Ceftazidime; Cephalosporins; Dose-Response Relationship, Drug; Enterobacter cloacae; Escherichia coli; Gram-Negative Bacteria; Gram-Positive Bacteria; In Vitro Techniques; Pseudomonas aeruginosa; Staphylococcus aureus | 1996 |
[New antimicrobial agent series IL: cefepime].
Topics: Bacteria; Bacterial Infections; beta-Lactamases; Cefepime; Ceftazidime; Cephalosporins; Clinical Trials as Topic; Controlled Clinical Trials as Topic; Drug Resistance, Microbial; Humans | 1996 |
Cefepime: a fourth-generation parenteral cephalosporin.
Topics: Cefepime; Cephalosporins; Drug Interactions; Humans; Randomized Controlled Trials as Topic | 1996 |
[Febrile neutropenia: empiric antibiotic therapy from 1975 to 1997].
Topics: Aminoglycosides; Anti-Bacterial Agents; Bacterial Infections; Cefepime; Ceftazidime; Cephalosporins; Drug Therapy, Combination; Fever; Gram-Negative Bacterial Infections; Gram-Positive Bacterial Infections; Humans; Imipenem; Meropenem; Neutropenia; Sepsis; Thienamycins | 1997 |
New antibiotics.
Topics: Anti-Infective Agents; Cefepime; Cephalosporins; Child; Fluoroquinolones; Humans; Meningitis, Bacterial; Meropenem; Naphthyridines; Thienamycins | 1998 |
The clinical potential of fourth-generation cephalosporins.
Topics: Bacterial Infections; Cefepime; Cefpirome; Cephalosporins; Clinical Trials as Topic; Humans; Microbial Sensitivity Tests; Streptococcus pneumoniae | 1998 |
[Cefepim in febrile neutropenic patients].
Topics: Adult; Cefepime; Cephalosporins; Child; Fever; Gentamicins; Humans; Neutropenia; Penicillins; Piperacillin | 1998 |
[Cefepime--a fourth generation cephalosporin antibiotic].
Topics: Bacterial Infections; Cefepime; Cephalosporins; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; Microbial Sensitivity Tests; Neutropenia; Peritonitis | 1999 |
[The use of cefepime for treating patients with severe hospital infections].
Topics: Bacterial Infections; Cefepime; Cephalosporins; Clinical Trials as Topic; Cross Infection; Female; Humans; Male | 1999 |
Cefepime microbiologic profile and update.
Topics: beta-Lactamases; Cefepime; Cephalosporins; Drug Resistance, Microbial; Enterobacteriaceae; Humans; Pseudomonas aeruginosa; Structure-Activity Relationship | 2001 |
Review of the pharmacokinetics of cefepime in children.
Topics: Adolescent; Cefepime; Cephalosporins; Child; Child, Preschool; Dose-Response Relationship, Drug; Female; Humans; Infant; Injections, Intramuscular; Injections, Intravenous; Male; Meningitis, Bacterial; Safety; Time Factors; Treatment Outcome | 2001 |
Empiric use of cefepime in the treatment of lower respiratory tract infections in children.
Topics: Adolescent; Cefepime; Cefotaxime; Ceftazidime; Cefuroxime; Cephalosporins; Child; Child, Preschool; Clinical Trials as Topic; Humans; Infant; Recurrence; Respiratory Tract Infections; Safety; Treatment Outcome | 2001 |
Empiric use of cefepime in the treatment of serious urinary tract infections in children.
Topics: Adolescent; Cefepime; Ceftazidime; Cephalosporins; Child; Child, Preschool; Humans; Infant; Multicenter Studies as Topic; Randomized Controlled Trials as Topic; Recurrence; Treatment Outcome; Urinary Tract Infections | 2001 |
Cefepime in the empiric treatment of meningitis in children.
Topics: Adolescent; Cefepime; Cefotaxime; Ceftriaxone; Cephalosporins; Child; Child, Preschool; Humans; Infant; Latin America; Meningitis, Bacterial; Randomized Controlled Trials as Topic; Safety; Treatment Failure; Treatment Outcome | 2001 |
Comparative study of cefepime versus ceftazidime in the empiric treatment of pediatric cancer patients with fever and neutropenia.
Topics: Adolescent; Adult; Bacterial Infections; Cefepime; Ceftazidime; Cephalosporins; Child; Child, Preschool; Fever; Humans; Infant; Neoplasms; Neutropenia; Safety; Treatment Outcome | 2001 |
The astonishing complexity of antibiotic resistance.
Topics: Cefepime; Cephalosporins; Drug Resistance, Microbial; Gram-Negative Bacteria; Gram-Negative Bacterial Infections; Humans; Porins | 2000 |
Antibiotic resistance in hospital infections: the role of newer cephalosporins.
Topics: beta-Lactam Resistance; beta-Lactamases; Cefepime; Ceftazidime; Cephalosporins; Cross Infection; Humans | 2000 |
Strategies for antibiotic selection in empirical therapy.
Topics: Aminoglycosides; Anti-Bacterial Agents; Cefepime; Cephalosporins; Cross Infection; Decision Making; Humans | 2000 |
[Cefepime (maxipime) in the treatment of abdominal surgical infections].
Topics: Abdomen; Bacterial Infections; Cefepime; Cephalosporins; Cholecystitis; Gastrointestinal Diseases; Peritonitis; Surgical Wound Infection | 2001 |
Pharmacodynamic considerations in the treatment of moderate to severe pseudomonal infections with cefepime.
Topics: Aminoglycosides; Anti-Bacterial Agents; Cefepime; Cephalosporins; Clinical Trials as Topic; Drug Therapy, Combination; Enterobacteriaceae; Enterobacteriaceae Infections; Humans; Microbial Sensitivity Tests; Pseudomonas aeruginosa; Pseudomonas Infections; Treatment Outcome | 2002 |
[A fourth generation cephalosporin--cefepime (maxipime) in pediatrics].
Topics: Adolescent; Bacterial Infections; Cefepime; Cephalosporins; Child; Child, Preschool; Humans; Infant; Pediatrics | 2001 |
[Cefepime (maxipine) in treating abdominal surgical infections].
Topics: Cefepime; Cephalosporins; Humans; Peritonitis; Surgical Wound Infection | 2001 |
[Use of maxipime in treating infections in neutropenic patients].
Topics: Bacterial Infections; Cefepime; Cephalosporins; Humans; Neutropenia | 2001 |
Retrospective review of neurotoxicity induced by cefepime and ceftazidime.
Topics: Aged; Cefepime; Ceftazidime; Cephalosporins; Female; Humans; Male; Medication Errors; Middle Aged; Neurotoxicity Syndromes; Peritoneal Dialysis, Continuous Ambulatory | 2003 |
Enterobacter cloacae ventriculitis successfully treated with cefepime and gentamicin: case report and review of the literature.
Topics: Cefepime; Cephalosporins; Cerebral Ventricles; Drug Therapy, Combination; Enterobacter cloacae; Enterobacteriaceae Infections; Female; Gentamicins; Humans; Middle Aged | 2003 |
Role of pharmacodynamics in designing dosage regimens for beta-lactams.
Topics: Anti-Bacterial Agents; Cefepime; Cephalosporins; Dose-Response Relationship, Drug; Humans; Meropenem; Penicillanic Acid; Piperacillin; Tazobactam; Thienamycins | 2003 |
Is there a rationale for the continuous infusion of cefepime? A multidisciplinary approach.
Topics: Bacterial Infections; Cefepime; Cephalosporins; Clinical Trials as Topic; Cystic Fibrosis; Drug Administration Schedule; Humans; Infusions, Intravenous; Microbial Sensitivity Tests; Treatment Outcome | 2003 |
[Cefepime: the new option of target antibiotic therapy].
Topics: Bacterial Infections; Cefepime; Cephalosporins; Humans | 2003 |
[Empirical cefepime monotherapy in febrile neutropenia].
Topics: Anti-Bacterial Agents; Bacterial Infections; Cefepime; Cephalosporins; Clinical Trials as Topic; Fever; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; Neutropenia; Pseudomonas aeruginosa; Sensitivity and Specificity | 2003 |
[Cefepime in the treatment of hospital-acquired pneumonia].
Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; Candida; Cefepime; Cephalosporins; Cross Infection; Fever; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; Middle Aged; Pneumonia; Treatment Outcome | 2003 |
Fatal hemorrhagic pneumonia caused by infection due to Kytococcus sedentarius--a pathogen or passenger?
Topics: Actinomycetales; Actinomycetales Infections; Acyclovir; Antineoplastic Combined Chemotherapy Protocols; Bacteremia; Bacterial Translocation; Cefepime; Cephalosporins; Clostridium Infections; Colistin; Cytarabine; Daunorubicin; Drug Therapy, Combination; Etoposide; Fatal Outcome; Hemoptysis; Humans; Hydroxyurea; Immunocompromised Host; Intestinal Mucosa; Leukemia, Myeloid, Acute; Male; Metronidazole; Middle Aged; Neutropenia; Pneumonia, Bacterial; Superinfection; Teicoplanin; Trimethoprim, Sulfamethoxazole Drug Combination | 2004 |
Cefepime-induced encephalopathy.
Topics: Anti-Bacterial Agents; Cefepime; Cephalosporins; Humans; Male; Middle Aged; Neurotoxicity Syndromes; Pleurisy | 2004 |
Cefepime: a review of its use in the management of hospitalized patients with pneumonia.
Topics: Cefepime; Cephalosporins; Community-Acquired Infections; Cross Infection; Drug Resistance, Microbial; Humans; Microbial Sensitivity Tests; Pneumonia, Bacterial | 2003 |
Intrapulmonary concentrations of cefepime.
Topics: Artifacts; Biological Availability; Cefepime; Cephalosporins; Drug Administration Schedule; Drug Monitoring; Humans; Infusions, Intravenous; Lung; Respiratory Mucosa; Temperature; Tissue Distribution; Treatment Outcome | 2004 |
Beta-lactam antibiotics: newer formulations and newer agents.
Topics: Amoxicillin-Potassium Clavulanate Combination; Anti-Bacterial Agents; beta-Lactams; Cefepime; Cephalosporins; Ertapenem; Humans; Lactams; United States | 2004 |
An adult case of Chryseobacterium meningosepticum meningitis.
Topics: Adult; Anti-Bacterial Agents; Cefepime; Cephalosporins; Chryseobacterium; Female; Flavobacteriaceae Infections; Humans; Meningitis, Bacterial | 2004 |
Treating serious infections: focus on cefepime.
Topics: Cefepime; Cephalosporins; Cross Infection; Humans; Neutropenia; Pneumonia, Bacterial | 2004 |
[Respiratory fluoroquinolones in the treatment of exacerbations of chronic obstructive lung disease].
Topics: Administration, Oral; Age Factors; Aged; Amoxicillin; Anti-Bacterial Agents; Bacteria; Cefepime; Cephalosporins; Ciprofloxacin; Clavulanic Acid; Fluoroquinolones; Humans; Injections, Intravenous; Ofloxacin; Pulmonary Disease, Chronic Obstructive; Risk Factors; Time Factors | 2004 |
[Study of cefepime in Russia].
Topics: Anti-Bacterial Agents; Cefepime; Cephalosporins; Cross Infection; Humans | 2004 |
Antimicrobial therapy for pulmonary pathogenic colonisation and infection by Pseudomonas aeruginosa in cystic fibrosis patients.
Topics: Amikacin; Anti-Bacterial Agents; Anti-Infective Agents; Bronchopneumonia; Cefepime; Ceftazidime; Cephalosporins; Ciprofloxacin; Colistin; Cystic Fibrosis; Drug Therapy, Combination; Humans; Inhalation; Injections, Intravenous; Lung Diseases; Pneumonia, Bacterial; Practice Guidelines as Topic; Pseudomonas aeruginosa; Pseudomonas Infections; Tobramycin | 2005 |
Empirical antibiotic monotherapy for febrile neutropenia: systematic review and meta-analysis of randomized controlled trials.
Topics: Anti-Bacterial Agents; beta-Lactamase Inhibitors; Carbapenems; Cefepime; Cephalosporins; Enzyme Inhibitors; Fever; Humans; Neutropenia; Penicillanic Acid; Penicillins; Quality Assurance, Health Care; Randomized Controlled Trials as Topic; Tazobactam; Treatment Outcome | 2006 |
[Role of cefepime in the treatment of hospital-acquired pneumonia].
Topics: Anti-Bacterial Agents; Cefepime; Cephalosporins; Cross Infection; Humans; Pneumonia, Bacterial | 2005 |
Extended-spectrum beta-lactamases and clinical outcomes: current data.
Topics: Anti-Bacterial Agents; Bacteremia; beta-Lactam Resistance; beta-Lactamases; Cefepime; Cephalosporins; Cross Infection; Escherichia coli; Escherichia coli Infections; Humans; Klebsiella; Klebsiella Infections; Treatment Outcome | 2006 |
Spontaneous adrenal hemorrhage during pregnancy: a review of the literature and a case report of successful conservative management.
Topics: Adrenal Gland Diseases; Adult; Cefepime; Cephalosporins; Female; Hemorrhage; Humans; Infant, Newborn; Magnetic Resonance Imaging; Obesity, Morbid; Pregnancy; Pregnancy Complications; Pregnancy Outcome; Pregnancy Trimester, Third; Tomography, X-Ray Computed; Treatment Outcome | 2005 |
Cefepime neurotoxicity: case report, pharmacokinetic considerations, and literature review.
Topics: Aged; Anti-Bacterial Agents; Cefepime; Cephalosporins; Electroencephalography; Female; Humans; Myoclonus; Neurotoxicity Syndromes; Renal Insufficiency, Chronic; Urinary Tract Infections | 2006 |
Cefepime versus ceftazidime: considerations for empirical use in critically ill patients.
Topics: Anti-Bacterial Agents; Cefepime; Ceftazidime; Cephalosporins; Community-Acquired Infections; Critical Illness; Cross Infection; Drug Resistance; Economics, Pharmaceutical; Humans; Pneumonia, Bacterial | 2007 |
Pasteurella multocida sepsis, due to a scratch from a pet cat, in a post-chemotherapy neutropenic patient with non-Hodgkin lymphoma.
Topics: Aged; Animals; Animals, Domestic; Anti-Bacterial Agents; Anticoagulants; Bites and Stings; Cats; Cefepime; Cephalosporins; Chondroitin Sulfates; Dermatan Sulfate; Female; Granulocyte Colony-Stimulating Factor; Heparitin Sulfate; Humans; Lymphoma, Non-Hodgkin; Neutropenia; Pasteurella Infections; Pasteurella multocida; Sepsis | 2007 |
Efficacy and safety of cefepime: a systematic review and meta-analysis.
Topics: Anti-Bacterial Agents; Cefepime; Cephalosporins; Gram-Negative Bacterial Infections; Gram-Positive Bacterial Infections; Humans; Randomized Controlled Trials as Topic | 2007 |
Pacemaker pocket infection due to Mycobacterium goodii: case report and review of the literature.
Topics: Aged, 80 and over; Anti-Infective Agents; Cefepime; Cephalosporins; Drug Therapy, Combination; Humans; Injections, Intravenous; Male; Mycobacterium Infections; Pacemaker, Artificial; Trimethoprim, Sulfamethoxazole Drug Combination; Vancomycin | 2008 |
The safety of cefepime in the treatment of infection.
Topics: Bacterial Infections; Cefepime; Cephalosporins; Clinical Trials as Topic; Humans; Neurotoxicity Syndromes | 2008 |
Cefepime and its role in pediatric infections.
Topics: Anti-Bacterial Agents; Bacterial Infections; Cefepime; Cephalosporins; Drug Resistance, Bacterial; Humans; Infant; Infant, Newborn; Molecular Structure; Patents as Topic; Structure-Activity Relationship; Treatment Outcome | 2008 |
Cefepime-induced nonconvulsive status epilepticus: case report and review.
Topics: Adolescent; Anti-Bacterial Agents; Cefepime; Cephalosporins; Female; Humans; Kidney Failure, Chronic; Status Epilepticus | 2009 |
Cefepime: a reappraisal in an era of increasing antimicrobial resistance.
Topics: Aged; Aged, 80 and over; Anti-Bacterial Agents; Bacterial Infections; Cefepime; Cephalosporins; Child; Drug Resistance, Bacterial; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; Retrospective Studies | 2008 |
Early endovascular coiling of posterior communicating artery saccular aneurysm in the setting of Staphylococcus bacteremia: case report and review of the literature.
Topics: Aged; Anti-Bacterial Agents; Cefepime; Cephalosporins; Embolization, Therapeutic; Female; Humans; Staphylococcal Infections; Subarachnoid Hemorrhage; Vancomycin | 2010 |
Efficacy and safety of cefepime in pediatric patients: a systematic review and meta-analysis.
Topics: Anti-Bacterial Agents; Cefepime; Cephalosporins; Child; Humans; Randomized Controlled Trials as Topic; Treatment Outcome | 2010 |
Meta-analysis of a possible signal of increased mortality associated with cefepime use.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Bacterial Infections; Cefepime; Cephalosporins; Child; Child, Preschool; Clinical Trials as Topic; Female; Fever of Unknown Origin; Humans; Infant; Infant, Newborn; Male; Middle Aged; Neutropenia; Pneumonia, Bacterial; Skin Diseases, Bacterial; Survival Analysis; Urinary Tract Infections; Young Adult | 2010 |
Meta-analysis of a possible signal of increased mortality associated with cefepime use.
Topics: Anti-Bacterial Agents; Bacterial Infections; Biomarkers; Cefepime; Cephalosporins; Clinical Trials as Topic; Humans | 2010 |
Anti-pseudomonal beta-lactams for the initial, empirical, treatment of febrile neutropenia: comparison of beta-lactams.
Topics: Anti-Bacterial Agents; beta-Lactams; Cefepime; Ceftazidime; Cephalosporins; Fever; Humans; Imipenem; Meropenem; Neutropenia; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Pseudomonas aeruginosa; Pseudomonas Infections; Randomized Controlled Trials as Topic; Thienamycins | 2010 |
Eradication of Pseudomonas aeruginosa in an adult patient with cystic fibrosis.
Topics: Adult; Anti-Infective Agents; Cefepime; Cephalosporins; Cystic Fibrosis; Drug Therapy, Combination; Female; Humans; Infusions, Intravenous; Pseudomonas aeruginosa; Pseudomonas Infections; Tobramycin | 2011 |
Antibiotics in critically ill patients: a systematic review of the pharmacokinetics of β-lactams.
Topics: Anti-Bacterial Agents; beta-Lactams; Cefepime; Cefpirome; Ceftazidime; Cephalosporins; Critical Illness; Humans; Imipenem; Infections; Meropenem; Piperacillin; Thienamycins | 2011 |
Optimization of anti-pseudomonal antibiotics for cystic fibrosis pulmonary exacerbations: II. cephalosporins and penicillins.
Topics: Anti-Bacterial Agents; beta-Lactam Resistance; Cefepime; Ceftazidime; Cephalosporins; Clavulanic Acids; Cystic Fibrosis; Disease Progression; Drug Therapy, Combination; Humans; Microbial Sensitivity Tests; Penicillanic Acid; Penicillins; Piperacillin; Piperacillin, Tazobactam Drug Combination; Pseudomonas aeruginosa; Pseudomonas Infections; Ticarcillin | 2013 |
Determining a clinical framework for use of cefepime and β-lactam/β-lactamase inhibitors in the treatment of infections caused by extended-spectrum-β-lactamase-producing Enterobacteriaceae.
Topics: Anti-Bacterial Agents; beta-Lactamase Inhibitors; beta-Lactamases; Cefepime; Cephalosporins; Enterobacteriaceae; Enterobacteriaceae Infections; Enzyme Inhibitors; Humans; Treatment Outcome | 2014 |
Intermittent hemodialysis treatment in cefepime-induced neurotoxicity: case report, pharmacokinetic modeling, and review of the literature.
Topics: Aged, 80 and over; Anti-Bacterial Agents; Cefepime; Cephalosporins; Female; Humans; Kidney Diseases; Models, Biological; Renal Dialysis | 2015 |
Evaluating outcomes of alternative dosing strategies for cefepime: a qualitative systematic review.
Topics: Anti-Bacterial Agents; Bacterial Infections; Cause of Death; Cefepime; Cephalosporins; Dose-Response Relationship, Drug; Drug Administration Schedule; Humans; Infusions, Intravenous; Length of Stay; Microbial Sensitivity Tests; Prospective Studies; Retrospective Studies; Treatment Outcome | 2015 |
Carbapenems versus alternative antibiotics for the treatment of bloodstream infections caused by Enterobacter, Citrobacter or Serratia species: a systematic review with meta-analysis.
Topics: Anti-Bacterial Agents; Bacteremia; beta-Lactamase Inhibitors; Carbapenems; Cefepime; Cephalosporins; Enterobacteriaceae Infections; Humans; Quinolones; Serratia Infections; Survival Analysis; Treatment Outcome | 2016 |
Treatment options for extended-spectrum beta-lactamase (ESBL) and AmpC-producing bacteria.
Topics: Anti-Bacterial Agents; Bacterial Proteins; beta-Lactamase Inhibitors; beta-Lactamases; beta-Lactams; Cefepime; Cephalosporins; Drug Resistance, Bacterial; Drug Therapy, Combination; Enterobacteriaceae; Enterobacteriaceae Infections; Gram-Negative Aerobic Bacteria; Gram-Negative Bacterial Infections; Humans; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination | 2016 |
Bloodstream infections in neutropenic cancer patients: A practical update.
Topics: Anti-Bacterial Agents; Bacteremia; Cefepime; Cephalosporins; Disease Management; Drug Resistance, Bacterial; Febrile Neutropenia; Fluoroquinolones; Gram-Negative Bacteria; Humans; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Pre-Exposure Prophylaxis; Risk Factors | 2016 |
Cefepime-Induced Neurotoxicity Despite Dose Adjustment for Renal Disease: A Brief Report and Review of the Literature.
Topics: Adolescent; Anti-Bacterial Agents; Cefepime; Cephalosporins; Fever of Unknown Origin; Humans; Male; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Renal Insufficiency | 2017 |
A case of Cefepime encephalopathy, being difficult to distinguish from non-convulsive status epilepticus during the treatment of bacterial meningitis.
Topics: Anti-Bacterial Agents; Brain Diseases; Cefepime; Cephalosporins; Diagnosis, Differential; Electroencephalography; Humans; Magnetic Resonance Imaging; Male; Meningitis, Bacterial; Middle Aged; Status Epilepticus | 2016 |
The Use of Noncarbapenem β-Lactams for the Treatment of Extended-Spectrum β-Lactamase Infections.
Topics: Anti-Bacterial Agents; beta-Lactam Resistance; beta-Lactamase Inhibitors; beta-Lactamases; Cefepime; Cephalosporins; Cephamycins; Enterobacteriaceae; Enterobacteriaceae Infections; Humans; Microbial Sensitivity Tests; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Treatment Outcome | 2017 |
Valvular Heart Disease in Adults: Infective Endocarditis.
Topics: Anti-Bacterial Agents; Blood Culture; Carbapenems; Cefepime; Cephalosporins; Cross Infection; Echocardiography; Endocarditis; Endocarditis, Bacterial; Gentamicins; Heart Valve Prosthesis; Humans; Prosthesis-Related Infections; Staphylococcal Infections; Staphylococcus aureus; Streptococcal Infections; Vancomycin | 2017 |
Antibiotic Dosing in Continuous Renal Replacement Therapy.
Topics: Anti-Bacterial Agents; Cefepime; Ceftazidime; Cephalosporins; Computer Simulation; Critical Illness; Humans; Levofloxacin; Meropenem; Microbial Sensitivity Tests; Monte Carlo Method; Penicillanic Acid; Piperacillin; Renal Replacement Therapy; Sepsis; Tazobactam; Thienamycins | 2017 |
Cefepime-induced neurotoxicity: a systematic review.
Topics: Anti-Bacterial Agents; Cefepime; Cephalosporins; Consciousness Disorders; Drug-Related Side Effects and Adverse Reactions; Humans; Neurotoxicity Syndromes; Seizures | 2017 |
Prolonged Cefepime-Induced Neurotoxicity in a Patient with End-Stage Renal Disease.
Topics: Anti-Bacterial Agents; Cefepime; Cephalosporins; Female; Humans; Kidney Failure, Chronic; Neurotoxicity Syndromes; Status Epilepticus | 2022 |
Clinical Pharmacokinetics and Pharmacodynamics of Cefepime.
Topics: Adult; Anti-Bacterial Agents; Cefepime; Cephalosporins; Critical Illness; Humans; Microbial Sensitivity Tests | 2022 |
Cefepime-induced neurotoxicity: systematic review.
Topics: Anti-Bacterial Agents; Brain Diseases; Cefepime; Cephalosporins; Humans; Neurotoxicity Syndromes | 2022 |
Mechanism of action of cefiderocol.
Topics: Animals; Anti-Bacterial Agents; beta-Lactamase Inhibitors; beta-Lactamases; Carbapenems; Cattle; Cefepime; Cefiderocol; Ceftazidime; Cephalosporins; Gram-Negative Bacteria; Iron; Quinolones; Serine; Tetracyclines | 2022 |
The role of cefiderocol in clinical practice.
Topics: Anti-Bacterial Agents; beta-Lactamases; Carbapenems; Cefepime; Cefiderocol; Ceftazidime; Cephalosporins; Drug Resistance, Multiple, Bacterial; Gram-Negative Bacteria; Gram-Negative Bacterial Infections; Humans; Microbial Sensitivity Tests; Pseudomonas aeruginosa | 2022 |
Antibiotic therapy for nonfermenting Gram-negative bacilli infections: future perspectives.
Topics: Anti-Bacterial Agents; Cefepime; Cephalosporins; Gram-Negative Bacteria; Gram-Negative Bacterial Infections; Humans; Microbial Sensitivity Tests | 2023 |
158 trial(s) available for cephalosporin c and cefepime
| Article | Year |
|---|---|
Tissue concentrations of cefepime in acute cholecystitis patients.
Topics: Acute Disease; Adult; Ascitic Fluid; Bile; Cefepime; Cephalosporins; Cholecystectomy; Cholecystitis; Female; Gallbladder; Humans; Injections, Intravenous; Male; Middle Aged; Premedication; Regression Analysis | 1992 |
[Dose finding study of cefepime for chronic respiratory infections].
Topics: Adolescent; Adult; Aged; Bacteria; Cefepime; Ceftazidime; Cephalosporins; Chronic Disease; Dose-Response Relationship, Drug; Female; Humans; Male; Middle Aged; Respiratory Tract Infections | 1992 |
[A comparative study of cefepime for bacterial pneumonia].
Topics: Adolescent; Adult; Aged; Bacterial Infections; Cefepime; Ceftazidime; Cephalosporins; Female; Humans; Male; Microbial Sensitivity Tests; Middle Aged; Pneumonia | 1992 |
[A comparative study of cefepime for chronic respiratory tract infections].
Topics: Adolescent; Adult; Aged; Bacteria; Cefepime; Ceftazidime; Cephalosporins; Chronic Disease; Female; Humans; Male; Microbial Sensitivity Tests; Middle Aged; Respiratory Tract Infections | 1992 |
Multiple dose pharmacokinetics, safety, and effects on faecal microflora, of cefepime in healthy volunteers.
Topics: Bacteroides; Cefepime; Cephalosporins; Clostridioides difficile; Double-Blind Method; Drug Administration Schedule; Escherichia coli; Feces; Female; Humans; Injections, Intravenous; Male | 1992 |
Cefepime. Pharmacokinetics and clinical response in patients with cystic fibrosis.
Topics: Adolescent; Adult; California; Cefepime; Cephalosporins; Child; Child, Preschool; Chronic Disease; Cystic Fibrosis; Female; Hospitals, Pediatric; Humans; Infusions, Intravenous; Male; Metabolic Clearance Rate; Microbial Sensitivity Tests; Respiratory Tract Infections; Severity of Illness Index; Sputum; Tissue Distribution; Vital Capacity | 1992 |
An evaluation of the penetration of cefepime into prostate tissue in patients undergoing elective prostatectomy.
Topics: Aged; Aged, 80 and over; Cefepime; Cephalosporins; Humans; Male; Middle Aged; Prostate; Prostatectomy | 1992 |
Analysis of cefepime tissue penetration into human appendix.
Topics: Adolescent; Adult; Appendectomy; Appendicitis; Appendix; Ascitic Fluid; Cefepime; Cephalosporins; Clindamycin; Female; Gangrene; Gentamicins; Humans; Injections, Intravenous; Intestinal Perforation; Male; Metronidazole; Rupture, Spontaneous | 1991 |
A randomized trial of cefepime (BMY-28142) and ceftazidime for the treatment of pneumonia.
Topics: Adult; Aged; Aged, 80 and over; Bacteria; Cefepime; Ceftazidime; Cephalosporins; Drug Hypersensitivity; Female; Humans; Male; Microbial Sensitivity Tests; Middle Aged; Pneumonia | 1991 |
Randomized comparison of cefepime and ceftazidime for treatment of skin, surgical wound, and complicated urinary tract infections in hospitalized subjects.
Topics: Adult; Aged; Aged, 80 and over; Cefepime; Ceftazidime; Cephalosporins; Female; Hospitalization; Humans; Male; Middle Aged; Random Allocation; Skin Diseases, Infectious; Surgical Wound Infection; Urinary Tract Infections | 1991 |
[Cefepime in the treatment of patients with surgical infections].
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Cefepime; Cephalosporins; Female; Humans; Male; Middle Aged; Surgical Wound Infection | 1991 |
Safety, tolerance, and pharmacokinetic evaluation of cefepime after administration of single intravenous doses.
Topics: Adult; Cefepime; Ceftazidime; Cephalosporins; Double-Blind Method; Drug Evaluation; Humans; Infusions, Intravenous; Male; Molecular Structure; Reference Values | 1990 |
Open trial of cefepime (BMY 28142) for infections in hospitalized patients.
Topics: Cefepime; Cephalosporins; Clinical Trials as Topic; Follow-Up Studies; Hospitalization; Humans; Infections; Lung; Microbial Sensitivity Tests; Respiratory Tract Infections; Skin; Skin Diseases, Infectious; Urinary Tract Infections; Urine | 1990 |
Safety, tolerance, and pharmacokinetics of cefepime administered intramuscularly to healthy subjects.
Topics: Adult; Biological Availability; Cefepime; Cephalosporins; Drug Administration Schedule; Follow-Up Studies; Humans; Injections, Intramuscular; Male; Random Allocation; Single-Blind Method | 1990 |
Randomized comparison of cefepime and ceftazidime for treatment of hospitalized patients with gram-negative bacteremia.
Topics: Aged; Bacteremia; Cefepime; Ceftazidime; Cephalosporins; Drug Eruptions; Escherichia coli Infections; Female; Gram-Negative Bacterial Infections; Humans; Klebsiella Infections; Klebsiella pneumoniae; Male; Middle Aged; Prospective Studies; Safety | 1995 |
Prospective randomized comparison of cefepime and cefotaxime for treatment of bacterial meningitis in infants and children.
Topics: Adolescent; Cefepime; Cefotaxime; Cephalosporins; Child; Child, Preschool; Humans; Infant; Meningitis, Bacterial; Prospective Studies | 1995 |
[Cefepim--profile of a new cephalosporin].
Topics: Bacterial Infections; Cefepime; Cephalosporins; Critical Care; Humans | 1994 |
Low-dosage cefepime as treatment for serious bacterial infections.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Bacteremia; Bacteria; Bacterial Infections; Cefepime; Cephalosporins; Female; Freeze Drying; Humans; Male; Microbial Sensitivity Tests; Middle Aged; Powders; Respiratory Tract Infections; Skin Diseases, Infectious; Therapeutic Equivalency; Urinary Tract Infections | 1993 |
A non-comparative, multicentre study of cefepime in the treatment of serious bacterial infections.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Bacteria; Bacterial Infections; Cefepime; Cephalosporins; Female; Humans; Male; Microbial Sensitivity Tests; Middle Aged; Respiratory Tract Infections; Risk Factors; Sepsis; Skin Diseases, Infectious; Urinary Tract Infections | 1993 |
Cefepime as treatment for osteomyelitis and other severe bacterial infections.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Bacterial Infections; Cefepime; Cephalosporins; Female; Humans; Injections, Intravenous; Male; Middle Aged; Osteomyelitis | 1993 |
Cefepime monotherapy for the empirical treatment of fever in granulocytopenic cancer patients.
Topics: Adolescent; Adult; Aged; Agranulocytosis; Bacterial Infections; Cefepime; Cephalosporins; Female; Fever; Humans; Leukocyte Count; Male; Middle Aged; Neoplasms; Pilot Projects; Prospective Studies | 1993 |
A comparative study of cefepime and ceftazidime in the treatment of community-acquired lower respiratory tract infections.
Topics: Adult; Aged; Aged, 80 and over; Bacteria; Cefepime; Ceftazidime; Cephalosporins; Community-Acquired Infections; Female; Follow-Up Studies; Humans; Injections, Intramuscular; Injections, Intravenous; Male; Middle Aged; Radiography; Respiratory Tract Infections | 1993 |
International comparative study of cefepime and ceftazidime in the treatment of serious bacterial infections.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Bacteria; Bacterial Infections; Cefepime; Ceftazidime; Cephalosporins; Europe; Female; Humans; Male; Microbial Sensitivity Tests; Middle Aged; Treatment Failure | 1993 |
Cefepime versus cefotaxime in the treatment of lower respiratory tract infections.
Topics: Adult; Aged; Aged, 80 and over; Bronchopneumonia; Cefepime; Cefotaxime; Cephalosporins; Female; Humans; Injections, Intravenous; Male; Middle Aged; Respiratory Tract Infections; Treatment Outcome | 1993 |
Randomized comparative study of cefepime and cefotaxime in the treatment of acute obstetric and gynaecological infections.
Topics: Adolescent; Adult; Aged; Bacterial Infections; Cefepime; Cefotaxime; Cephalosporins; Female; Genital Diseases, Female; Humans; Middle Aged; Pregnancy; Puerperal Infection | 1993 |
A non-comparative study of the efficacy and tolerance of cefepime in combination with amikacin in the treatment of severe infections in patients in intensive care.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amikacin; Bacteremia; Bacterial Infections; Cefepime; Cephalosporins; Critical Care; Cross Infection; Drug Therapy, Combination; Female; Follow-Up Studies; France; Humans; Male; Middle Aged; Respiratory Tract Infections; Shock, Septic | 1993 |
Cefepime compared with ceftazidime as initial therapy for serious bacterial infections and sepsis syndrome.
Topics: Aged; Aged, 80 and over; Bacterial Infections; Cefepime; Ceftazidime; Cephalosporins; Humans; Neutropenia; Treatment Failure; Treatment Outcome | 1994 |
A clinical comparison of cefepime and metronidazole versus gentamicin and clindamycin in the antibiotic management of surgically treated advanced appendicitis.
Topics: Adolescent; Adult; Appendicitis; Cefepime; Cephalosporins; Clindamycin; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Female; Gentamicins; Humans; Male; Metronidazole; Middle Aged; Treatment Outcome | 1993 |
A randomized study of cefepime versus the combination of gentamicin and mezlocillin as an adjunct to surgical treatment in patients with acute cholecystitis.
Topics: Acute Disease; Adult; Aged; Cefepime; Cephalosporins; Chemotherapy, Adjuvant; Cholecystitis; Drug Therapy, Combination; Female; Gentamicins; Humans; Male; Mezlocillin; Middle Aged; Treatment Outcome | 1993 |
Cefepime for infections of the biliary tract.
Topics: Adult; Bacterial Infections; Biliary Tract Diseases; Cefepime; Cephalosporins; Drug Administration Schedule; Drug Therapy, Combination; Female; Gentamicins; Humans; Male; Mezlocillin; Middle Aged; Prospective Studies; Treatment Outcome | 1993 |
Pharmacokinetics of cefepime in cystic fibrosis patients.
Topics: Adolescent; Adult; Cefepime; Cephalosporins; Child; Cystic Fibrosis; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Humans; Male; Middle Aged | 1993 |
Cefepime pharmacokinetics in patients with acute cholecystitis undergoing cholecystectomy.
Topics: Acute Disease; Adult; Cefepime; Cephalosporins; Cholecystectomy; Cholecystitis; Female; Humans; Infusions, Intravenous; Male; Middle Aged; Surgical Wound Infection | 1993 |
Clinical applications of a new parenteral antibiotic in the treatment of severe bacterial infections.
Topics: Acute Disease; Analysis of Variance; Bacterial Infections; Cefepime; Ceftazidime; Cephalosporins; Cross Infection; Female; Humans; Infusions, Intravenous; Male; Middle Aged; United States | 1996 |
A new therapeutic option for the treatment of pneumonia.
Topics: Acute Disease; Aged; Canada; Cefepime; Ceftazidime; Cephalosporins; Double-Blind Method; Female; Humans; Male; Middle Aged; Pneumonia, Bacterial; Puerto Rico; United States | 1996 |
Treatment of urinary tract infections: selecting an appropriate broad-spectrum antibiotic for nosocomial infections.
Topics: Bacteremia; Cefepime; Ceftazidime; Cephalosporins; Cross Infection; Female; Humans; Male; Middle Aged; Time Factors; United States; Urinary Tract Infections | 1996 |
Clinical experience with single agent and combination regimens in the management of infection in the febrile neutropenic patient.
Topics: Anti-Bacterial Agents; Cefepime; Ceftazidime; Cephalosporins; Drug Therapy, Combination; Female; Fever; Gentamicins; Humans; Male; Middle Aged; Neoplasms; Neutropenia; Penicillins; Piperacillin; Prospective Studies; Superinfection; Vancomycin | 1996 |
Current and future management of serious skin and skin-structure infections.
Topics: Bacteria; Cefepime; Ceftazidime; Cephalosporins; Female; Humans; Infusions, Intravenous; Male; Microbial Sensitivity Tests; Middle Aged; Skin Diseases; Skin Diseases, Bacterial | 1996 |
Cefepime/amikacin versus ceftazidime/amikacin as empirical therapy for febrile episodes in neutropenic patients: a comparative study. The French Cefepime Study Group.
Topics: Amikacin; Anti-Bacterial Agents; Bacteremia; Bacterial Infections; Cefepime; Ceftazidime; Cephalosporins; Drug Resistance, Microbial; Drug Therapy, Combination; Female; Fever; Gastrointestinal Diseases; Gram-Negative Bacteria; Gram-Positive Bacteria; Hematologic Neoplasms; Humans; Male; Neutropenia; Skin Diseases, Bacterial; Soft Tissue Infections; Urinary Tract Infections | 1997 |
Cefepime versus ceftazidime in the treatment of lower respiratory tract infections.
Topics: Aged; Cefepime; Ceftazidime; Cephalosporins; Community-Acquired Infections; Female; Humans; Male; Microbial Sensitivity Tests; Middle Aged; Respiratory Tract Infections | 1997 |
Open randomized study of cefepime versus piperacillin-gentamicin for treatment of febrile neutropenic cancer patients.
Topics: Adult; Bacterial Infections; Cefepime; Cephalosporins; Drug Therapy, Combination; Female; Fever; Gentamicins; Humans; Male; Middle Aged; Neoplasms; Neutropenia; Piperacillin | 1997 |
[Comparative in vitro activity of cefepime: multicenter study in Aquitaine].
Topics: Acinetobacter; Anti-Bacterial Agents; Cefepime; Cephalosporins; Enterobacteriaceae; France; In Vitro Techniques; Microbial Sensitivity Tests; Phenotype; Pseudomonas aeruginosa; Serotyping | 1997 |
Pharmacokinetics of cefepime during continuous venovenous hemodiafiltration.
Topics: Acute Kidney Injury; Aged; Cefepime; Cephalosporins; Female; Half-Life; Hemofiltration; Humans; Infusions, Intravenous; Male; Middle Aged | 1997 |
A randomized, double-blind clinical trial comparing cefepime plus metronidazole with imipenem-cilastatin in the treatment of complicated intra-abdominal infections. Cefepime Intra-abdominal Infection Study Group.
Topics: Abdomen; Abdominal Abscess; Adult; Aged; Antitrichomonal Agents; Appendicitis; Cefepime; Cephalosporins; Cilastatin; Double-Blind Method; Drug Therapy, Combination; Female; Gastrointestinal Diseases; Humans; Imipenem; Infections; Male; Metronidazole; Middle Aged; Peritonitis; Treatment Outcome | 1997 |
Cefepime versus ceftriaxone for empiric treatment of hospitalized patients with community-acquired pneumonia. The Cefepime Study Group.
Topics: Cefepime; Ceftriaxone; Cephalosporins; Community-Acquired Infections; Female; Humans; Male; Middle Aged; Pneumonia | 1998 |
Piperacillin/tazobactam versus cefepime as initial empirical antimicrobial therapy in febrile neutropenic patients: a prospective randomized pilot study.
Topics: Anti-Infective Agents; Cefepime; Cephalosporins; Drug Therapy, Combination; Fever; Humans; Neutropenia; Penicillanic Acid; Pilot Projects; Piperacillin; Prognosis; Prospective Studies; Tazobactam | 1998 |
Cefepine vs. ceftazidime treatment of pyelonephritis: a European, randomized, controlled study of 300 pediatric cases. European Society for Paediatric Infectious Diseases (ESPID) Pyelonephritis Study Group.
Topics: Administration, Oral; Cefepime; Ceftazidime; Cephalosporins; Child; Child, Preschool; Drug Therapy, Combination; Female; Humans; Infant; Injections, Intravenous; Male; Pyelonephritis; Trimethoprim, Sulfamethoxazole Drug Combination | 1998 |
Decreasing antibiotic resistance of Enterobacteriaceae by introducing a new antibiotic combination therapy for neutropenic fever patients.
Topics: Adult; Amikacin; Cefepime; Ceftazidime; Cephalosporins; Drug Resistance, Microbial; Drug Therapy, Combination; Enterobacteriaceae; Enterobacteriaceae Infections; Fever; Hematologic Diseases; Humans; Microbial Sensitivity Tests; Neutropenia; Teicoplanin; Vancomycin | 1998 |
Cefepime versus imipenem-cilastatin as empirical monotherapy in 400 febrile patients with short duration neutropenia. CEMIC (Study Group of Infectious Diseases in Cancer).
Topics: Antineoplastic Agents; Cefepime; Cephalosporins; Cilastatin; Drug Therapy, Combination; Fever; Humans; Imipenem; Neoplasms; Neutropenia; Risk Factors; Survival Analysis | 1998 |
Efficacy and safety of cefepime treatment in Chinese patients with severe bacterial infections: in comparison with ceftazidime treatment.
Topics: Asian People; Bacteremia; Bacterial Infections; Cefepime; Ceftazidime; Cephalosporins; Humans; Pneumonia, Bacterial; Taiwan; Urinary Tract Infections | 1998 |
[Phare study. Comparative study of combined cefepime-amikacin versus ceftazidime combined with amikacin in the treatment of nosocomial pneumonias in ventilated patients. Multicenter group study].
Topics: Amikacin; Cefepime; Ceftazidime; Cephalosporins; Cross Infection; Double-Blind Method; Drug Therapy, Combination; Female; France; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; Male; Middle Aged; Pneumonia, Bacterial; Respiration, Artificial; Survival Rate | 1999 |
Treatment of community-acquired pneumonia in the elderly: the role of cefepime, a fourth-generation cephalosporin.
Topics: Aged; Aged, 80 and over; Cefepime; Ceftriaxone; Cephalosporins; Community-Acquired Infections; Double-Blind Method; Female; Humans; Male; Pneumonia, Bacterial; Prospective Studies; Treatment Outcome | 1999 |
[Continuous versus intermittent cefepime infusion in critical care. Preliminary results].
Topics: Bacteremia; Cefepime; Cephalosporins; Critical Care; Drug Administration Schedule; Female; Gram-Negative Bacterial Infections; Humans; Infusions, Intravenous; Length of Stay; Male; Middle Aged | 1999 |
A randomized trial of cefepime and ceftazidime for the treatment of community-acquired pneumonia.
Topics: Aged; Cefepime; Ceftazidime; Cephalosporins; Community-Acquired Infections; Drug Administration Schedule; Drug Costs; Female; Humans; Male; Middle Aged; Pneumonia; Treatment Outcome | 1999 |
Cefepime as empirical monotherapy in febrile patients with hematological malignancies and neutropenia: a randomized, single-center phase II trial.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Cefepime; Cephalosporins; Female; Fever; Gram-Positive Bacterial Infections; Hematologic Neoplasms; Humans; Male; Middle Aged; Neutropenia | 1999 |
Low plasma cefepime levels in critically ill septic patients: pharmacokinetic modeling indicates improved troughs with revised dosing.
Topics: Adult; Aged; Anti-Bacterial Agents; Cefepime; Cephalosporins; Computer Simulation; Critical Illness; Female; Humans; Male; Metabolic Clearance Rate; Middle Aged; Pseudomonas aeruginosa | 1999 |
Pharmacokinetics of cefepime in patients with thermal burn injury.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Bacterial Infections; Burns; Cefepime; Cephalosporins; Chromatography, High Pressure Liquid; Creatinine; Female; Half-Life; Humans; Male; Middle Aged; Spectrophotometry, Ultraviolet | 1999 |
[The results of a multicenter study of the comparative activity of cefepime and other antibiotics against the causative agents of severe hospital infections (the Micromax program)].
Topics: Acute Disease; Anti-Bacterial Agents; Cefepime; Cephalosporins; Cross Infection; Gram-Negative Bacteria; Gram-Negative Bacterial Infections; Gram-Positive Bacteria; Gram-Positive Bacterial Infections; Humans; Microbial Sensitivity Tests; Russia | 1999 |
[The efficacy of cefepime (Maxipime) in the treatment of abdominal sepsis in surgical patients].
Topics: Abdomen; Aged; Anti-Infective Agents; APACHE; Cefepime; Cephalosporins; Drug Therapy, Combination; Female; Humans; Male; Metronidazole; Middle Aged; Peritonitis; Prospective Studies; Sepsis; Surgical Wound Infection; Time Factors | 1999 |
[Cefepime in the treatment of infection in neutropenic patients].
Topics: Adolescent; Adult; Bacterial Infections; Cefepime; Cephalosporins; Female; Fever; Humans; Male; Middle Aged; Neutropenia; Time Factors; Treatment Outcome | 1999 |
[The role of cefepime, a 4th-generation cephalosporin, in treating patients with surgical sepsis].
Topics: Adolescent; Adult; Aged; Bacteremia; Cefepime; Cephalosporins; Gram-Negative Bacterial Infections; Gram-Positive Bacterial Infections; Humans; Middle Aged; Severity of Illness Index; Surgical Wound Infection; Systemic Inflammatory Response Syndrome | 1999 |
The pharmacokinetics, safety, and tolerance of cefepime administered as an intravenous bolus or as a rapid infusion.
Topics: Adult; Area Under Curve; Cefepime; Cephalosporins; Chromatography, High Pressure Liquid; Female; Half-Life; Humans; Infusions, Intravenous; Injections, Intravenous; Male; Spectrophotometry, Ultraviolet | 1999 |
Cefepime versus ceftazidime for the treatment of serious bacterial infections.
Topics: Adult; Aged; Aged, 80 and over; Bacterial Infections; Cefepime; Ceftazidime; Cephalosporins; Drug Resistance, Microbial; Female; Humans; Male; Middle Aged | 1999 |
In vitro evaluation of cefepime and other broad-spectrum beta-lactams in 22 medical centers in Japan: a phase II trial comparing two annual organism samples. The Japan Antimicrobial Resistance Study Group.
Topics: Anti-Bacterial Agents; Bacteria; Cefepime; Cephalosporinase; Cephalosporins; Enterobacteriaceae; Gram-Negative Bacteria; Humans; Microbial Sensitivity Tests | 1999 |
Pharmacokinetics and pharmacodynamics of cefepime administered by intermittent and continuous infusion.
Topics: Adult; Algorithms; Area Under Curve; Blood Bactericidal Activity; Cefepime; Cephalosporins; Enterobacter cloacae; Female; Half-Life; Humans; Infusions, Intravenous; Male; Methicillin Resistance; Microbial Sensitivity Tests; Pseudomonas aeruginosa; Staphylococcus aureus | 2000 |
A multicenter randomized trial of prophylaxis with intravenous cefepime + metronidazole or ceftriaxone + metronidazole in colorectal surgery. The 230 Study Group.
Topics: Adult; Aged; Aged, 80 and over; Anti-Infective Agents; Antibiotic Prophylaxis; Cefepime; Ceftriaxone; Cephalosporins; Colorectal Surgery; Drug Therapy, Combination; Female; Humans; Infusions, Intravenous; Male; Metronidazole; Middle Aged; Surgical Wound Infection | 2000 |
Plasma, urine and skin pharmacokinetics of cefepime in burns patients.
Topics: Adult; Area Under Curve; Burns; Cefepime; Cephalosporins; Female; Half-Life; Humans; Injections, Intravenous; Male; Middle Aged | 2000 |
Cefepime versus ceftazidime as empiric therapy for fever in neutropenic patients with cancer.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Bacterial Infections; Cefepime; Ceftazidime; Cephalosporins; Double-Blind Method; Female; Fever; Humans; Male; Middle Aged; Mycoses; Neoplasms; Neutropenia; Prospective Studies; Treatment Failure; Treatment Outcome | 2000 |
Randomized comparison of cefepime versus ceftazidime monotherapy for fever and neutropenia in children with solid tumors.
Topics: Adolescent; Antineoplastic Agents; Bacterial Infections; Candidiasis; Cefepime; Ceftazidime; Cephalosporins; Child; Child, Preschool; Female; Fever; Humans; Infant; Male; Neoplasms; Neutropenia; Statistics, Nonparametric | 2001 |
Pharmacokinetic population study to describe cefepime lung concentrations.
Topics: Administration, Oral; Aged; Cefepime; Cephalosporins; Female; Half-Life; Humans; Lung; Male; Middle Aged; Prospective Studies | 2001 |
Comparative study of cefepime versus ceftazidime in the empiric treatment of pediatric cancer patients with fever and neutropenia.
Topics: Adolescent; Adult; Bacterial Infections; Cefepime; Ceftazidime; Cephalosporins; Child; Child, Preschool; Fever; Humans; Infant; Neoplasms; Neutropenia; Safety; Treatment Outcome | 2001 |
Pancreatic concentrations of cefepime.
Topics: Adult; Aged; Cefepime; Cephalosporins; Female; Humans; Infusions, Intravenous; Male; Middle Aged; Pancreatitis | 2001 |
Cefepime versus vancomycin plus netilmicin therapy for continuous ambulatory peritoneal dialysis-associated peritonitis.
Topics: Adult; Aged; Anti-Bacterial Agents; Cefepime; Cephalosporins; Female; Gentamicins; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; Male; Middle Aged; Netilmicin; Peritoneal Dialysis, Continuous Ambulatory; Peritonitis; Prospective Studies; Treatment Outcome; Vancomycin | 2001 |
Cost-effectiveness of cefepime + netilmicin or ceftazidime + amikacin or meropenem monotherapy in febrile neutropenic children with malignancy in Turkey.
Topics: Adolescent; Adult; Amikacin; Cefepime; Cephalosporins; Child; Child, Preschool; Cost-Benefit Analysis; Drug Therapy, Combination; Female; Fever; Humans; Infant; Male; Meropenem; Neoplasms; Netilmicin; Neutropenia; Prospective Studies; Thienamycins; Turkey | 2001 |
[Cefepime in the treatment of osteomyelitis caused by Gram negative bacilli].
Topics: Acute Disease; Adult; Aged; Aged, 80 and over; Cefepime; Cephalosporins; Chronic Disease; Female; Gram-Negative Bacterial Infections; Humans; Male; Middle Aged; Osteomyelitis; Patient Selection | 2000 |
Cefepime versus cefotaxime for empirical treatment of bacterial pneumonia in HIV-infected patients: an open, randomized trial.
Topics: Adult; Cefepime; Cefotaxime; Cephalosporins; Empiricism; Female; HIV Infections; Humans; Male; Pneumonia, Bacterial; Treatment Outcome | 2001 |
Pharmacokinetics of cefepime during continuous renal replacement therapy in critically ill patients.
Topics: Adult; Aged; Area Under Curve; Cefepime; Cephalosporins; Chromatography, High Pressure Liquid; Critical Illness; Female; Hemofiltration; Humans; Kidney Failure, Chronic; Male; Middle Aged; Prospective Studies; Spectrophotometry, Ultraviolet | 2001 |
Comparison of cefepime and ceftazidime in combination with amikacin in the empirical treatment of high-risk patients with febrile neutropenia: a prospective, randomized, multicenter study.
Topics: Adolescent; Adult; Amikacin; Anti-Bacterial Agents; Cefepime; Ceftazidime; Cephalosporins; Drug Therapy, Combination; Fever; Humans; Leukemia; Lymphoma, Non-Hodgkin; Neutropenia; Prospective Studies; Risk Factors; Treatment Outcome | 2001 |
A randomized monocentric trial in febrile neutropenic patients: ceftriaxone and gentamicin vs cefepime and gentamicin.
Topics: Anti-Bacterial Agents; Cefepime; Ceftriaxone; Cephalosporins; Drug Therapy, Combination; Fever; Gentamicins; Humans; Neutropenia; Prospective Studies; Treatment Outcome | 2002 |
Cefepime versus ceftazidime as empiric monotherapy for fever and neutropenia in children with cancer.
Topics: Adolescent; Bacterial Infections; Cefepime; Ceftazidime; Cephalosporins; Child; Child, Preschool; Female; Fever; Humans; Infant; Male; Neoplasms; Neutropenia; Treatment Outcome | 2002 |
Cefepime plus amikacin versus piperacillin-tazobactam plus amikacin for initial antibiotic therapy in haematology patients with febrile neutropenia: results of an open, randomized, multicentre trial.
Topics: Adult; Amikacin; Anti-Bacterial Agents; Cefepime; Cephalosporins; Drug Therapy, Combination; Female; Fever; Hematologic Neoplasms; Hematopoietic Stem Cell Transplantation; Humans; Male; Neutropenia; Penicillanic Acid; Piperacillin; Tazobactam; Treatment Outcome | 2002 |
Safety and efficacy of cefepime versus ceftazidime in the treatment of severe infections.
Topics: Adolescent; Aged; Anti-Bacterial Agents; Bacterial Infections; Cefepime; Ceftazidime; Cephalosporins; Female; Gram-Negative Bacterial Infections; Gram-Positive Bacterial Infections; Humans; Male; Middle Aged; Pneumonia, Bacterial; Taiwan; Treatment Outcome; Urinary Tract Infections | 2002 |
Cefepime or carbapenem treatment for febrile neutropenia as a single agent is as effective as a combination of 4th-generation cephalosporin + aminoglycosides: comparative study.
Topics: Adult; Algorithms; Aminoglycosides; Anti-Bacterial Agents; Carbapenems; Cefepime; Cephalosporins; Drug Administration Schedule; Drug Therapy, Combination; Female; Fever; Humans; Leukemia; Lymphoma; Male; Neutropenia | 2002 |
Cefepime monotherapy as an empirical initial treatment of patients with febrile neutropenia.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amikacin; Anti-Bacterial Agents; Antineoplastic Agents; Bacterial Infections; Cefepime; Cephalosporins; Drug Therapy, Combination; Female; Fever; Humans; Male; Middle Aged; Multicenter Studies as Topic; Neoplasms; Neutropenia; Teicoplanin; Treatment Outcome; Vancomycin | 2002 |
A multicenter comparative study of cefepime versus broad-spectrum antibacterial therapy in moderate and severe bacterial infections.
Topics: Abdominal Abscess; Adolescent; Adult; Aged; Aged, 80 and over; Cefepime; Cephalosporins; Community-Acquired Infections; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Peritonitis; Pneumonia, Bacterial; Prospective Studies; Sepsis; Severity of Illness Index; South America; Treatment Outcome; Urinary Tract Infections | 2002 |
Continuous infusion versus intermittent administration of cefepime in patients with Gram-negative bacilli bacteraemia.
Topics: Adult; Area Under Curve; Cefepime; Cephalosporins; Chromatography, High Pressure Liquid; Cross-Over Studies; Drug Administration Schedule; Drug Stability; Female; Gram-Negative Bacterial Infections; Humans; Infusions, Intravenous; Injections, Intravenous; Male; Microbial Sensitivity Tests; Middle Aged; Prospective Studies; Time Factors | 2002 |
Antibiotic prophylaxis in elective thoracic surgery: cefuroxime versus cefepime.
Topics: Adult; Aged; Anti-Bacterial Agents; Antibiotic Prophylaxis; Blood Sedimentation; Body Temperature; Bronchopneumonia; Cefepime; Cefuroxime; Cephalosporins; Combined Modality Therapy; Cost-Benefit Analysis; Disease Susceptibility; Double-Blind Method; Elective Surgical Procedures; Female; Humans; Leukocyte Count; Male; Middle Aged; Random Allocation; Surgical Wound Infection; Thoracic Surgical Procedures; Treatment Outcome | 2003 |
Cefepime versus ticarcillin and clavulanate potassium and aztreonam for febrile neutropenia therapy in high-dose chemotherapy patients.
Topics: Adult; Aged; Anti-Bacterial Agents; Antineoplastic Agents; Aztreonam; Cefepime; Cephalosporins; Clavulanic Acid; Costs and Cost Analysis; Drug Therapy, Combination; Female; Fever; Humans; Immunocompromised Host; Male; Middle Aged; Neoplasms; Neutropenia; Opportunistic Infections; Peripheral Blood Stem Cell Transplantation; Ticarcillin | 2003 |
Diffusion of cefepime into cancellous and cortical bone tissue.
Topics: Aged; Aged, 80 and over; Bone and Bones; Bone Diseases, Infectious; Cefepime; Cephalosporins; Diffusion; Female; Humans; Male; Microbial Sensitivity Tests; Tissue Distribution | 2003 |
[Comparative clinical and epidemiological evaluation of beta-lactam antibiotics in the treatment of intraabdominal infections].
Topics: Abdomen; Anti-Bacterial Agents; Bacterial Infections; Cefepime; Cefoperazone; Cephalosporins; Clinical Trials as Topic; Costs and Cost Analysis; Drug Combinations; Humans; Imipenem; Meropenem; Models, Economic; Sulbactam; Thienamycins | 2003 |
Serum bactericidal activity of trovafloxacin, in combination with cefepime or amikacin, in healthy volunteers.
Topics: Adult; Amikacin; Anti-Bacterial Agents; Anti-Infective Agents; Bacteria; Cefepime; Cephalosporins; Cross-Over Studies; Female; Fluoroquinolones; Humans; Male; Naphthyridines | 2003 |
Treatment of febrile neutropenic patients with cancer who require hospitalization: a prospective randomized study comparing imipenem and cefepime.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amikacin; Anti-Bacterial Agents; Bacterial Infections; Catheterization, Central Venous; Cefepime; Cephalosporins; Female; Fever; Hospitalization; Humans; Imipenem; Male; Middle Aged; Neoplasms; Neutropenia; Practice Guidelines as Topic; Prospective Studies; Risk Factors; Vancomycin | 2003 |
Cefepime versus cefpirome: the importance of creatinine clearance.
Topics: Area Under Curve; Cefepime; Cefpirome; Cephalosporins; Chromatography, High Pressure Liquid; Creatinine; Critical Care; Half-Life; Humans; Infusions, Intravenous | 2003 |
Cefepime versus imipenem-cilastatin for treatment of nosocomial pneumonia in intensive care unit patients: a multicenter, evaluator-blind, prospective, randomized study.
Topics: Adult; Aged; APACHE; Cefepime; Cephalosporins; Cilastatin; Critical Care; Cross Infection; Double-Blind Method; Drug Therapy, Combination; Endpoint Determination; Female; Humans; Imipenem; Male; Middle Aged; Pneumonia, Pneumococcal; Prospective Studies; Protease Inhibitors; Respiration, Artificial; Thienamycins | 2003 |
[Experience with maxipime in neurosurgical clinic].
Topics: Anesthesia Department, Hospital; Antibiotic Prophylaxis; Bronchitis; Cefepime; Cephalosporins; Humans; Inflammation; Infusions, Intravenous; Intensive Care Units; Leukocyte Count; Nervous System Diseases; Neutrophils; Postoperative Complications; Surgery Department, Hospital; Treatment Outcome | 2003 |
[Cefepime treatment efficacy in surgical patients].
Topics: Antibiotic Prophylaxis; Bacteria; Cardiovascular Diseases; Cefepime; Cephalosporins; Drug Therapy, Combination; Humans; Injections, Intravenous; Intraoperative Care; Male; Microbial Sensitivity Tests; Postoperative Care; Postoperative Complications; Tracheal Stenosis; Treatment Outcome | 2003 |
[Cefepime/amikacin in the empirical antibacterial therapy for patients with hemoblastosis of different forms].
Topics: Amikacin; Anti-Bacterial Agents; Bacterial Infections; Cefepime; Ceftriaxone; Cephalosporins; Drug Therapy, Combination; Hematologic Neoplasms; Humans; Leukocyte Count; Neutropenia; Neutrophils; Time Factors; Treatment Outcome | 2003 |
Cefepime vs. Meropenem as empirical therapy for neutropenic fever in children with lymphoma and solid tumours.
Topics: Adolescent; Anti-Bacterial Agents; Bacteremia; Cefepime; Cephalosporins; Child; Child, Preschool; Empiricism; Female; Fever; Granulocyte Colony-Stimulating Factor; Humans; Infant; Lymphoma, Non-Hodgkin; Male; Meropenem; Neoplasms; Neutropenia; Therapeutic Equivalency; Thienamycins; Treatment Outcome | 2004 |
Randomized trial of cefepime monotherapy or cefepime in combination with amikacin as empirical therapy for febrile neutropenia.
Topics: Amikacin; Antineoplastic Agents; Bacteremia; Cefepime; Cephalosporins; Drug Therapy, Combination; Female; Fever; Hematologic Diseases; Humans; Immunocompromised Host; Japan; Leukemia; Male; Neutropenia; Opportunistic Infections | 2004 |
A prospective, randomized study comparing cefepime and imipenem-cilastatin in the empirical treatment of febrile neutropenia in patients treated for haematological malignancies.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cefepime; Cephalosporins; Cilastatin; Cilastatin, Imipenem Drug Combination; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Combinations; Female; Fever; Follow-Up Studies; Hematologic Neoplasms; Humans; Imipenem; Male; Middle Aged; Neutropenia; Probability; Prospective Studies; Risk Assessment; Single-Blind Method; Survival Analysis; Sweden; Treatment Outcome | 2004 |
Cefepime in critically ill patients: continuous infusion vs. an intermittent dosing regimen.
Topics: Adult; Aged; Amikacin; Anti-Bacterial Agents; Area Under Curve; Cefepime; Cephalosporins; Critical Illness; Drug Therapy, Combination; Female; Gram-Negative Bacteria; Gram-Negative Bacterial Infections; Humans; Infusions, Intravenous; Injections, Intravenous; Male; Microbial Sensitivity Tests; Middle Aged; Prospective Studies; Time Factors; Treatment Outcome | 2005 |
Subcutaneous administration of cefepime.
Topics: Adult; Cefepime; Cephalosporins; Female; Humans; Infusions, Parenteral; Male; Middle Aged; Reference Values; Subcutaneous Tissue | 2005 |
[Therapeutic effects of cefepime and sulbactam/cefoperazone on moderate and severe respiratory tract infection in children].
Topics: Anti-Bacterial Agents; Cefepime; Cefoperazone; Cephalosporins; Child; Child, Preschool; Drug Therapy, Combination; Female; Humans; Infant; Male; Pneumonia, Bacterial; Sulbactam | 2005 |
High-dose cefepime as an alternative treatment for infections caused by TEM-24 ESBL-producing Enterobacter aerogenes in severely-ill patients.
Topics: Adult; Aged; Anti-Bacterial Agents; Bacterial Proteins; beta-Lactamases; Carbapenems; Cefepime; Cephalosporins; Critical Illness; Cross Infection; Drug Therapy, Combination; Enterobacter aerogenes; Enterobacteriaceae Infections; Female; Humans; Intensive Care Units; Male; Microbial Sensitivity Tests; Middle Aged; Retrospective Studies; Treatment Outcome | 2006 |
Pilot study of continuous infusion cefepime in adult patients with cystic fibrosis.
Topics: Adult; Anti-Bacterial Agents; Cefepime; Cephalosporins; Cystic Fibrosis; Humans; Infusions, Intravenous; Metabolic Clearance Rate; Pilot Projects; Time Factors | 2006 |
Cefepime vs. Ampicillin/Sulbactam and Aztreonam as antibiotic prophylaxis in neurosurgical patients with external ventricular drain: result of a prospective randomized controlled clinical trial.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Ampicillin; Antibiotic Prophylaxis; Aztreonam; Cefepime; Cephalosporins; Child; Child, Preschool; Drug Combinations; Female; Humans; Infections; Male; Middle Aged; Monobactams; Neurosurgical Procedures; Penicillins; Postoperative Complications; Prospective Studies; Treatment Outcome; Ventriculoperitoneal Shunt | 2006 |
A randomized, open-label, multicenter comparative study of the efficacy and safety of piperacillin-tazobactam and cefepime for the empirical treatment of febrile neutropenic episodes in patients with hematologic malignancies.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Cefepime; Cephalosporins; Female; Fever; Hematologic Neoplasms; Hematopoietic Stem Cell Transplantation; Humans; Leukemia; Male; Middle Aged; Neutropenia; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Treatment Outcome | 2006 |
Efficacy of intravenous ciprofloxacin in patients with febrile neutropenia refractory to initial therapy.
Topics: Adult; Aged; Algorithms; Carbapenems; Cefepime; Cephalosporins; Ciprofloxacin; Female; Fever; Hematologic Diseases; Humans; Male; Middle Aged; Neutropenia; Remission Induction; Salvage Therapy; Treatment Failure; Treatment Outcome | 2006 |
Ertapenem versus cefepime for initial empirical treatment of pneumonia acquired in skilled-care facilities or in hospitals outside the intensive care unit.
Topics: Aged; Anti-Bacterial Agents; beta-Lactams; Cefepime; Cephalosporins; Cross Infection; Double-Blind Method; Drug Administration Schedule; Enterobacteriaceae; Enterobacteriaceae Infections; Ertapenem; Female; Humans; Intensive Care Units; Male; Middle Aged; Pneumonia, Bacterial; Prospective Studies; Skilled Nursing Facilities | 2006 |
Cefepime monotherapy for treatment of febrile neutropenia in children.
Topics: Adolescent; Anti-Bacterial Agents; Cefepime; Cephalosporins; Child; Child, Preschool; Female; Fever; Humans; Infant; Malaysia; Male; Neoplasms; Neutropenia; Prospective Studies; Treatment Outcome; Vancomycin | 2006 |
Randomized study of cefepime versus ceftazidime plus amikacin in patients with solid tumors treated with high dose chemotherapy (HDC) and peripheral blood stem cell support (PBSCS) with febrile neutropenia.
Topics: Adult; Amikacin; Anti-Bacterial Agents; Antineoplastic Combined Chemotherapy Protocols; Cefepime; Ceftazidime; Cephalosporins; Drug Therapy, Combination; Female; Fever; Humans; Male; Middle Aged; Neoplasms; Neutropenia; Stem Cell Transplantation; Treatment Outcome | 2006 |
Selective immediate hypersensitivity to cefepime.
Topics: Anti-Bacterial Agents; Cefepime; Cephalosporins; Fever; Humans; Hypersensitivity, Immediate; Immunoglobulin E; Male; Middle Aged; Skin Tests | 2007 |
Cefepime cerebrospinal fluid concentrations in neonatal bacterial meningitis.
Topics: Anti-Bacterial Agents; Cefepime; Cephalosporins; Cross Infection; Dominican Republic; Female; Humans; Infant, Newborn; Infant, Premature; Intensive Care Units, Neonatal; Klebsiella pneumoniae; Male; Meningitis, Bacterial | 2007 |
A randomized comparison of empiric or pre-emptive antibiotic therapy after hematopoietic stem cell transplantation.
Topics: Adult; Anti-Bacterial Agents; Bacteremia; Bacterial Infections; Cefepime; Cephalosporins; Female; Fever; Hematopoietic Stem Cell Transplantation; Humans; Male; Neutropenia; Time Factors; Transplantation, Autologous; Transplantation, Homologous; Treatment Outcome | 2007 |
Once-daily cefepime versus ceftriaxone for nursing home-acquired pneumonia.
Topics: Aged; Aged, 80 and over; Anti-Bacterial Agents; Cefepime; Ceftriaxone; Cephalosporins; Cross Infection; Double-Blind Method; Drug Administration Schedule; Drug Costs; Female; Humans; Injections, Intramuscular; Male; Nursing Homes; Pneumonia, Bacterial | 2007 |
A randomized prospective study of cefepime plus metronidazole with imipenem-cilastatin in the treatment of intra-abdominal infections.
Topics: Abdominal Cavity; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; APACHE; Bacterial Infections; Cefepime; Cephalosporins; Cilastatin; Cilastatin, Imipenem Drug Combination; Drug Combinations; Drug Therapy, Combination; Female; Gastrointestinal Diseases; Hospitals, University; Humans; Imipenem; Male; Metronidazole; Middle Aged | 2007 |
Cefepime plus amikacin as an initial empirical therapy of febrile neutropenia in paediatric cancer patients.
Topics: Adolescent; Adult; Amikacin; Anti-Bacterial Agents; Cefepime; Cephalosporins; Child; Child, Preschool; Drug Therapy, Combination; Female; Fever; Humans; Infant; Male; Neoplasms; Neutropenia; Remission Induction | 2007 |
Influence of E. coli lipopolysaccharide induced fever on the plasma kinetics of cefepime in cross-bred calves.
Topics: Animals; Anti-Bacterial Agents; Area Under Curve; Cattle; Cattle Diseases; Cefepime; Cephalosporins; Escherichia coli; Fever; Half-Life; Lipopolysaccharides; Male; Time Factors | 2008 |
Efficacy and safety of cefepime in late-onset ventilator-associated pneumonia in infants: a pilot randomized and controlled study.
Topics: Anti-Bacterial Agents; Cefepime; Ceftazidime; Cephalosporins; Child, Preschool; Drug Resistance, Microbial; Female; Humans; Infant; Malaysia; Male; Microbial Sensitivity Tests; Pilot Projects; Pneumonia, Ventilator-Associated; Statistics as Topic | 2008 |
Panipenem versus cefepime as empirical monotherapy in adult cancer patients with febrile neutropenia: a prospective randomized trial.
Topics: Anti-Bacterial Agents; Bacterial Infections; Cefepime; Cephalosporins; Drug Therapy, Combination; Female; Fever; Humans; Male; Middle Aged; Neoplasms; Neutropenia; Prospective Studies; Survival Rate; Thienamycins; Treatment Outcome | 2008 |
Evaluation of area under the inhibitory curve (AUIC) and time above the minimum inhibitory concentration (T>MIC) as predictors of outcome for cefepime and ceftazidime in serious bacterial infections.
Topics: Aged; Anti-Bacterial Agents; APACHE; Area Under Curve; Bacteremia; Bacterial Infections; Cefepime; Ceftazidime; Cephalosporins; Endpoint Determination; Escherichia coli; Female; Humans; Klebsiella; Male; Microbial Sensitivity Tests; Predictive Value of Tests; Pseudomonas aeruginosa; Renal Insufficiency; Sepsis; Treatment Outcome | 2008 |
Cefepime in intensive care unit patients: validation of a population pharmacokinetic approach and influence of covariables.
Topics: Anti-Bacterial Agents; Bacteremia; Cefepime; Cephalosporins; Creatinine; Cross Infection; France; Humans; Infusions, Intravenous; Intensive Care Units; Metabolic Clearance Rate; Middle Aged; Models, Biological; Nonlinear Dynamics; Prospective Studies | 2008 |
Cefepime for prophylaxis of infections in the surgery of cholelithiasis. Results of a multicentric comparative trial.
Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Antibiotic Prophylaxis; Bacterial Infections; Cefepime; Ceftriaxone; Cephalosporins; Cholelithiasis; Female; Humans; Injections, Intravenous; Male; Middle Aged; Postoperative Complications | 2008 |
Pharmacokinetics of fusidic acid and cefepime in heart tissues: implications for a role in surgical prophylaxis.
Topics: Anti-Bacterial Agents; Antibiotic Prophylaxis; Cardiopulmonary Bypass; Cefepime; Cephalosporins; Female; Fusidic Acid; Heart Valve Prosthesis Implantation; Humans; Infusions, Intravenous; Male; Methicillin Resistance; Microbial Sensitivity Tests; Myocardium; Staphylococcus aureus; Staphylococcus epidermidis; Tissue Distribution | 2008 |
Efficacy and safety evaluation of fixed dose combination of cefepime and amikacin in comparison with cefepime alone in treatment of nosocomial pneumonia patients.
Topics: Adolescent; Adult; Amikacin; Anti-Bacterial Agents; Cefepime; Cephalosporins; Cross Infection; Drug Combinations; Female; Humans; Injections, Intravenous; Male; Middle Aged; Pneumonia, Bacterial; Pseudomonas Infections; Treatment Outcome | 2008 |
Cefepime/clindamycin vs. ceftriaxone/clindamycin for the empiric treatment of poisoned patients with aspiration pneumonia.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Cefepime; Ceftriaxone; Cephalosporins; Clindamycin; Drug Combinations; Empirical Research; Female; Humans; Male; Middle Aged; Pneumonia, Aspiration; Prospective Studies | 2008 |
Population pharmacokinetics of high-dose, prolonged-infusion cefepime in adult critically ill patients with ventilator-associated pneumonia.
Topics: Adult; Aged; Anti-Bacterial Agents; Cefepime; Cephalosporins; Critical Illness; Humans; Metabolic Clearance Rate; Microbial Sensitivity Tests; Middle Aged; Pneumonia, Ventilator-Associated | 2009 |
Effects of an alternative cefepime dosing strategy in pulmonary and bloodstream infections caused by Enterobacter spp, Citrobacter freundii, and Pseudomonas aeruginosa: a single-center, open-label, prospective, observational study.
Topics: Anti-Bacterial Agents; Bacteremia; Cefepime; Cephalosporins; Citrobacter freundii; Enterobacter; Enterobacteriaceae Infections; Female; Humans; Logistic Models; Male; Microbial Sensitivity Tests; Middle Aged; Prospective Studies; Pseudomonas aeruginosa; Pseudomonas Infections; Respiratory Tract Infections; Risk Factors; Severity of Illness Index; Treatment Outcome | 2009 |
Piperacillin/tazobactam versus cefepime for the empirical treatment of pediatric cancer patients with neutropenia and fever: a randomized and open-label study.
Topics: Adolescent; Anti-Bacterial Agents; Cefepime; Cephalosporins; Child; Child, Preschool; Female; Fever; Humans; Infant; Male; Neutropenia; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Prospective Studies | 2009 |
Cefepime monotherapy is as effective as ceftriaxone plus amikacin in pediatric patients with cancer and high-risk febrile neutropenia in a randomized comparison.
Topics: Adolescent; Amikacin; Anti-Bacterial Agents; Bacterial Infections; Cefepime; Ceftriaxone; Cephalosporins; Child; Child, Preschool; Drug Therapy, Combination; Female; Hematologic Neoplasms; Humans; Immunocompromised Host; Infant; Male; Neutropenia; Treatment Outcome; Young Adult | 2009 |
Clinical efficacy and safety of cefepime in febrile neutropenic patients with lung cancer.
Topics: Aged; Aged, 80 and over; Anti-Bacterial Agents; Antineoplastic Agents; Blood; Cefepime; Cephalosporins; Female; Fever; Humans; Lung Neoplasms; Male; Middle Aged; Neutropenia; Sputum | 2010 |
Low-dose beta-lactam plus amikacin in febrile neutropenia: cefepime vs. piperacillin/tazobactam, a randomized trial.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amikacin; Anti-Bacterial Agents; Cefepime; Cephalosporins; Female; Fever of Unknown Origin; Humans; Incidence; Male; Middle Aged; Neutropenia; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Poisoning; Prospective Studies; Treatment Outcome; Young Adult | 2010 |
[Application of preparation quadrocef in the treatment of surgical sepsis].
Topics: Adult; Aged; Anti-Bacterial Agents; APACHE; Cefepime; Cephalosporins; Digestive System Diseases; Female; Humans; Male; Middle Aged; Peritonitis; Postoperative Complications; Sepsis; Treatment Outcome | 2011 |
A prospective study of cefepime versus ticarcilline/clavulanate as empirical treatment of febrile neutropenia in lymphoma patients.
Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; Antineoplastic Agents; Bacterial Infections; Cefepime; Cephalosporins; Child; Child, Preschool; Clavulanic Acid; Drug Therapy, Combination; Female; Fever; Humans; Infant; Infant, Newborn; Lymphoma; Male; Middle Aged; Neutropenia; Prospective Studies; Ticarcillin; Treatment Outcome; Young Adult | 2011 |
Population pharmacokinetics of four β-lactams in critically ill septic patients comedicated with amikacin.
Topics: Adult; Aged; Aged, 80 and over; Algorithms; Amikacin; Anti-Bacterial Agents; beta-Lactams; Cefepime; Ceftazidime; Cephalosporins; Critical Illness; Drug Monitoring; Female; Humans; Male; Meropenem; Metabolic Clearance Rate; Middle Aged; Models, Biological; Piperacillin; Sepsis; Thienamycins; Tissue Distribution; Treatment Outcome | 2012 |
Prospective randomized study of cefepime, panipenem, or meropenem monotherapy for patients with hematological disorders and febrile neutropenia.
Topics: Adolescent; Adult; Anti-Bacterial Agents; Carbapenems; Cefepime; Cephalosporins; Female; Fever; Hematologic Diseases; Humans; Male; Meropenem; Neutropenia; Prospective Studies; Thienamycins; Treatment Outcome; Young Adult | 2013 |
Randomized controlled trial comparing ciprofloxacin and cefepime in febrile neutropenic patients with hematological malignancies.
Topics: Adolescent; Adult; Aged; Algorithms; Anti-Bacterial Agents; Cefepime; Cephalosporins; Ciprofloxacin; Female; Fever; Hematologic Neoplasms; Humans; Male; Middle Aged; Neutropenia; Treatment Outcome; Young Adult | 2013 |
Prolonged infusion antibiotics for suspected gram-negative infections in the ICU: a before-after study.
Topics: Aged; Anti-Bacterial Agents; beta-Lactams; Cefepime; Cephalosporins; Cohort Studies; Cross Infection; Drug Administration Schedule; Female; Gram-Negative Bacteria; Gram-Negative Bacterial Infections; Hospitals, Teaching; Hospitals, Urban; Humans; Infusions, Intravenous; Intensive Care Units; Length of Stay; Male; Meropenem; Middle Aged; Missouri; Penicillanic Acid; Pilot Projects; Piperacillin; Piperacillin, Tazobactam Drug Combination; Thienamycins | 2013 |
Antibiotic rotation for febrile neutropenic patients with hematological malignancies: clinical significance of antibiotic heterogeneity.
Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Bacteremia; beta-Lactam Resistance; Cefepime; Cephalosporins; Ciprofloxacin; Drug Administration Schedule; Female; Fever; Gram-Negative Bacterial Infections; Hematologic Neoplasms; Humans; Male; Meropenem; Middle Aged; Neutropenia; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Prospective Studies; Thienamycins | 2013 |
Prophylactic first-line antibiotics reduce infectious fever and shorten hospital stay during chemotherapy-induced agranulocytosis in childhood acute myeloid leukemia.
Topics: Adolescent; Agranulocytosis; Anti-Bacterial Agents; Antineoplastic Combined Chemotherapy Protocols; Cefepime; Cephalosporins; Child; Child, Preschool; Female; Fever; Humans; Infection Control; Length of Stay; Leukemia, Myeloid, Acute; Male; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Prospective Studies; Vancomycin | 2014 |
Outpatient versus inpatient IV antibiotic management for pediatric oncology patients with low risk febrile neutropenia: a randomised trial.
Topics: Adolescent; Anti-Bacterial Agents; Cefepime; Cephalosporins; Child; Child, Preschool; Febrile Neutropenia; Female; Humans; Inpatients; Male; Neoplasms; Outpatients; Quality of Life; Risk Factors | 2014 |
Cefepime monotherapy for febrile neutropenia in patients with lung cancer.
Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Antineoplastic Agents; Cefepime; Cephalosporins; Chemoradiotherapy; Chemotherapy-Induced Febrile Neutropenia; Female; Humans; Lung Neoplasms; Male; Middle Aged | 2014 |
Multicenter, double-blind, randomized clinical trial of parenterally administered Cefoselis versus Cefepime for the treatment of acute bacterial infections.
Topics: Acute Disease; Anti-Bacterial Agents; Bacterial Infections; Cefepime; Ceftizoxime; Cephalosporins; Double-Blind Method; Female; Humans; Male; Respiratory Tract Infections; Urinary Tract Infections | 2014 |
A randomized trial of cefozopran versus cefepime as empirical antibiotic treatment of febrile neutropenia in pediatric cancer patients.
Topics: Adolescent; Adult; Anti-Bacterial Agents; Cefepime; Cefozopran; Cephalosporins; Child; Child, Preschool; Febrile Neutropenia; Female; Humans; Infant; Infant, Newborn; Male; Neoplasms | 2014 |
Cefozopran, meropenem, or imipenem-cilastatin compared with cefepime as empirical therapy in febrile neutropenic adult patients: A multicenter prospective randomized trial.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Cefepime; Cefozopran; Cephalosporins; Chemotherapy-Induced Febrile Neutropenia; Cilastatin; Cilastatin, Imipenem Drug Combination; Drug Combinations; Humans; Imipenem; Male; Meropenem; Middle Aged; Prospective Studies; Thienamycins; Young Adult | 2015 |
Comparison between piperacillin/tazobactam and cefepime monotherapies as an empirical therapy for febrile neutropenia in children with hematological and malignant disorders: A prospective, randomized study.
Topics: Adolescent; Adult; Anti-Bacterial Agents; Bacterial Infections; Cefepime; Cephalosporins; Child; Child, Preschool; Febrile Neutropenia; Female; Hematologic Neoplasms; Humans; Infant; Infant, Newborn; Male; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Prospective Studies; Young Adult | 2015 |
Risk factors and scoring system for predicting bacterial resistance to cefepime as used empirically in haematology wards.
Topics: Adult; Aged; Bacteremia; Cefepime; Cephalosporins; Drug Resistance, Bacterial; Female; Gram-Negative Bacteria; Hospital Departments; Humans; Male; Microbial Sensitivity Tests; Middle Aged | 2015 |
Adequacy of high-dose cefepime regimen in febrile neutropenic patients with hematological malignancies.
Topics: Aged; Anti-Bacterial Agents; Cefepime; Cephalosporins; Febrile Neutropenia; Female; Hematologic Neoplasms; Humans; Male; Microbial Sensitivity Tests; Middle Aged | 2015 |
Cefepime combined with amoxicillin/clavulanic acid: a new choice for the KPC-producing K. pneumoniae infection.
Topics: Adult; Aged; Amoxicillin-Potassium Clavulanate Combination; Anti-Bacterial Agents; Bacterial Proteins; beta-Lactamases; Cefepime; Cephalosporins; Drug Therapy, Combination; Female; Humans; Klebsiella Infections; Klebsiella pneumoniae; Male; Middle Aged; Minocycline; Tigecycline | 2015 |
A randomized open label study of 'imipenem vs. cefepime' in spontaneous bacterial peritonitis.
Topics: Adult; Anti-Bacterial Agents; Ascitic Fluid; Bacterial Infections; Cefepime; Cephalosporins; Cross Infection; Drug Resistance, Multiple; Drug Therapy, Combination; Female; Humans; Imipenem; India; Liver Cirrhosis; Male; Middle Aged; Paracentesis; Peritonitis; Risk Factors; Severity of Illness Index; Survival Analysis; Time Factors | 2016 |
A clinical evaluation of efficacy and safety of cefepime monotherapy versus piperacillin-tazobactam in patients of paediatric age group with febrile neutropenia in a tertiary care centre of north India.
Topics: Adolescent; Anti-Bacterial Agents; Bacterial Infections; Cefepime; Cephalosporins; Child; Child, Preschool; Drug Therapy, Combination; Febrile Neutropenia; Female; Fever; Humans; India; Male; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Prospective Studies; Tertiary Care Centers; Treatment Outcome | 2016 |
Cefepime versus Ceftriaxone for perioperative systemic antibiotic prophylaxis in elective orthopedic surgery at Bugando Medical Centre Mwanza, Tanzania: a randomized clinical study.
Topics: Adolescent; Adult; Anti-Bacterial Agents; Antibiotic Prophylaxis; Bacteria; Cefepime; Ceftriaxone; Cephalosporins; Elective Surgical Procedures; Female; Humans; Infusions, Intravenous; Male; Microbial Sensitivity Tests; Middle Aged; Orthopedic Procedures; Perioperative Care; Prospective Studies; Tanzania; Treatment Outcome; Young Adult | 2015 |
The efficacy and safety of cefepime or meropenem in the treatment of febrile neutropenia in patients with lung cancer. A randomized phase II study.
Topics: Aged; Aged, 80 and over; Anti-Bacterial Agents; Antineoplastic Agents; Cefepime; Cephalosporins; Febrile Neutropenia; Female; Humans; Lung Neoplasms; Male; Meropenem; Middle Aged; Prospective Studies; Thienamycins | 2016 |
A model-based analysis of the predictive performance of different renal function markers for cefepime clearance in the ICU.
Topics: Aged; Anti-Bacterial Agents; Biomarkers; Cefepime; Cephalosporins; Critical Illness; Female; Humans; Intensive Care Units; Kidney; Kidney Function Tests; Male; Metabolic Clearance Rate; Plasma; Urine | 2016 |
Extended infusion compared to standard infusion cefepime as empiric treatment of febrile neutropenia.
Topics: Adult; Aged; Anti-Bacterial Agents; Cefepime; Cephalosporins; Drug Therapy, Combination; Empirical Research; Febrile Neutropenia; Female; Hospital Mortality; Humans; Infusions, Intravenous; Male; Middle Aged; Pilot Projects; Prospective Studies; Time Factors; Treatment Outcome | 2018 |
Randomized controlled trial of piperacillin-tazobactam, cefepime and ertapenem for the treatment of urinary tract infection caused by extended-spectrum beta-lactamase-producing Escherichia coli.
Topics: Aged; Aged, 80 and over; Anti-Bacterial Agents; beta-Lactamase Inhibitors; beta-Lactamases; beta-Lactams; Cefepime; Cephalosporins; Cross Infection; Ertapenem; Escherichia coli; Escherichia coli Infections; Female; Genotype; Humans; Male; Middle Aged; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Prospective Studies; Republic of Korea; Tazobactam; Urinary Tract Infections | 2017 |
Influence of borderline cefepime MIC on the outcome of cefepime-susceptible Pseudomonas aeruginosa bacteremia treated with a maximal cefepime dose: a hospital-based retrospective study.
Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Bacteremia; Cefepime; Cephalosporins; Dose-Response Relationship, Drug; Female; Hospitals; Humans; Male; Middle Aged; Pseudomonas aeruginosa; Pseudomonas Infections; Retrospective Studies; Treatment Outcome | 2017 |
Cefepime vs. cefoperazone/sulbactam in combination with amikacin as empirical antibiotic therapy in febrile neutropenia.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amikacin; Anti-Bacterial Agents; Antibiotic Prophylaxis; Antineoplastic Agents; Cefepime; Cefoperazone; Cephalosporins; Chemotherapy-Induced Febrile Neutropenia; Child; Child, Preschool; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Neoplasms; Sulbactam; Survival Analysis; Withholding Treatment; Young Adult | 2018 |
Protocol and statistical analysis plan for the Antibiotic Choice On ReNal outcomes (ACORN) randomised clinical trial.
Topics: Acute Kidney Injury; Adult; Anti-Bacterial Agents; Cefepime; Cephalosporins; Humans; Kidney; Penicillins; Piperacillin; Piperacillin, Tazobactam Drug Combination; Prospective Studies; Randomized Controlled Trials as Topic; Retrospective Studies | 2023 |
919 other study(ies) available for cephalosporin c and cefepime
| Article | Year |
|---|---|
Molecular and biochemical characterization of the chromosome-encoded class A beta-lactamase BCL-1 from Bacillus clausii.
Topics: Amino Acid Sequence; Bacillus; Bacterial Proteins; beta-Lactamases; Chromosome Mapping; Chromosomes, Bacterial; Cloning, Molecular; Microbial Sensitivity Tests; Molecular Sequence Data; Molecular Weight; Sequence Homology, Amino Acid; Substrate Specificity | 2007 |
Computational analysis of structure-based interactions and ligand properties can predict efflux effects on antibiotics.
Topics: Anti-Bacterial Agents; beta-Lactams; Computational Biology; Drug Resistance, Bacterial; Hydrophobic and Hydrophilic Interactions; Ligands; Membrane Transport Proteins; Microbial Sensitivity Tests; Models, Molecular; Protein Binding; Protein Conformation; Quantitative Structure-Activity Relationship; Regression Analysis; Thermodynamics | 2012 |
[Effect of cefepime on adhesion and phagocytosis of Pseudomonas aeruginosa].
Topics: Bacterial Adhesion; Cefepime; Cephalosporins; Humans; Neutrophils; Phagocytosis; Pseudomonas aeruginosa; Respiratory Burst; Superoxides | 1992 |
Preliminary interpretive criteria for the Haemophilus Test Medium method using 30 micrograms cefepime disks.
Topics: Bacterial Typing Techniques; Cefepime; Cephalosporins; Haemophilus influenzae; Microbial Sensitivity Tests | 1992 |
Effects of age and gender on pharmacokinetics of cefepime.
Topics: Adult; Aged; Aged, 80 and over; Aging; Cefepime; Cephalosporins; Chromatography, High Pressure Liquid; Female; Half-Life; Humans; Injections, Intravenous; Male; Sex Factors; Spectrophotometry, Ultraviolet | 1992 |
[Study on the pharmacokinetics of cefepime (I)].
Topics: Animals; Autoradiography; Cefepime; Cephalosporins; Injections, Intravenous; Kidney; Male; Rats; Rats, Sprague-Dawley; Spleen; Tissue Distribution | 1992 |
[Study on the pharmacokinetics of cefepime (II)].
Topics: Animals; Blood Proteins; Cefepime; Cephalosporins; Dogs; Humans; Injections, Intravenous; Male; Protein Binding; Rats; Rats, Sprague-Dawley | 1992 |
Comparative in vitro activity of cefepime and four extended-spectrum beta-lactams on 1,251 aminoglycoside-resistant gram-negative hospital strains.
Topics: Aminoglycosides; Anti-Bacterial Agents; Aztreonam; Cefepime; Cefotaxime; Ceftazidime; Ceftriaxone; Cephalosporins; Drug Resistance, Microbial; Gram-Negative Bacteria; Microbial Sensitivity Tests; Species Specificity | 1992 |
Pharmacokinetics of cefepime dihydrochloride arginine in subjects with renal impairment.
Topics: Adult; Cefepime; Cephalosporins; Female; Glomerular Filtration Rate; Humans; Infusions, Intravenous; Kidney Diseases; Kidney Function Tests; Male; Pregnancy; Renal Dialysis | 1992 |
Pharmacodynamics of once-daily amikacin in various combinations with cefepime, aztreonam, and ceftazidime against Pseudomonas aeruginosa in an in vitro infection model.
Topics: Amikacin; Aztreonam; Cefepime; Ceftazidime; Cephalosporins; Drug Therapy, Combination; Half-Life; Humans; In Vitro Techniques; Pseudomonas Infections | 1992 |
Comparison of the antibacterial effects of cefepime and ceftazidime against Escherichia coli in vitro and in vivo.
Topics: Animals; Cefepime; Ceftazidime; Cephalosporins; Escherichia coli; Escherichia coli Infections; Male; Mice; Mice, Inbred Strains; Microbial Sensitivity Tests | 1992 |
Comparative in-vitro activities of newer cephalosporins cefclidin, cefepime, and cefpirome against ceftazidime- or imipenem-resistant Pseudomonas aeruginosa.
Topics: beta-Lactamases; Cefepime; Cefpirome; Ceftazidime; Cephalosporins; Drug Resistance, Microbial; Humans; Imipenem; Isoelectric Focusing; Microbial Sensitivity Tests; Pseudomonas aeruginosa | 1992 |
Describing and comparing in-vitro antimicrobial activity by the box-plot technique.
Topics: Anti-Bacterial Agents; Bacteria; Cefepime; Cephalosporins; Data Display; Meropenem; Methods; Microbial Sensitivity Tests; Thienamycins | 1992 |
[Cefepime (diHCl/L-arginine blend): intravenous continuous infusion and/or single dose subcutaneous toxicity study in rats and dogs].
Topics: Animals; Body Weight; Cefepime; Cephalosporins; Dogs; Female; Infusions, Intravenous; Injections, Subcutaneous; Male; Motor Activity; Rats | 1992 |
[Cefepime (BMY-28142 diHCl/L-arginine blend): one-month repeated dose subcutaneous toxicity study in rats].
Topics: Animals; Blood Chemical Analysis; Body Weight; Cefepime; Cephalosporins; Drinking; Eating; Female; Injections, Subcutaneous; Male; Organ Size; Rats; Time Factors; Urinalysis | 1992 |
[Reproductive and developmental toxicity studies on cefepime dihydrochloride administered subcutaneously to rats during the premating, gestation and lactation periods].
Topics: Animals; Animals, Newborn; Cefepime; Cephalosporins; Embryonic and Fetal Development; Female; Fertilization; Injections, Subcutaneous; Lactation; Male; Pregnancy; Pregnancy, Animal; Rats | 1992 |
[General pharmacology of cefepime].
Topics: Animals; Blood Coagulation; Cefepime; Cephalosporins; Depression, Chemical; Electrocardiography; Electroencephalography; Guinea Pigs; Hemodynamics; Male; Mice; Mice, Inbred ICR; Motor Activity; Muscle Relaxation; Muscle, Smooth; Rabbits; Stimulation, Chemical | 1992 |
Lack of pharmacokinetic interaction between cefepime and amikacin in humans.
Topics: Adult; Amikacin; Cefepime; Cephalosporins; Chromatography, High Pressure Liquid; Drug Administration Schedule; Drug Interactions; Humans; Infusions, Intravenous; Male | 1992 |
Pharmacokinetics of cefepime in patients undergoing continuous ambulatory peritoneal dialysis.
Topics: Cefepime; Cephalosporins; Dialysis Solutions; Drug Administration Schedule; Half-Life; Humans; Infusions, Intravenous; Middle Aged; Peritoneal Dialysis, Continuous Ambulatory; Random Allocation; Safety | 1992 |
Pharmacokinetic disposition and bactericidal activities of cefepime, ceftazidime, and cefoperazone in serum and blister fluid.
Topics: Adult; Bacteria; Blister; Body Fluids; Cefepime; Cefoperazone; Ceftazidime; Cephalosporins; Chromatography, High Pressure Liquid; Enterobacter cloacae; Humans; Male; Microbial Sensitivity Tests; Pseudomonas aeruginosa; Staphylococcus aureus | 1992 |
Proposed cefepime interpretive criteria for in-vitro susceptibility tests with Neisseria gonorrhoeae.
Topics: Cefepime; Cephalosporins; Data Interpretation, Statistical; Microbial Sensitivity Tests; Neisseria gonorrhoeae | 1992 |
[Affinities of PBPs of enterococci to cefepime and ampicillin].
Topics: Ampicillin; Bacterial Proteins; Carrier Proteins; Cefepime; Cephalosporins; Enterococcus; Hexosyltransferases; Muramoylpentapeptide Carboxypeptidase; Penicillin Resistance; Penicillin-Binding Proteins; Peptidyl Transferases; Protein Binding | 1992 |
Pharmacokinetics of cefepime after single and multiple intravenous administrations in healthy subjects.
Topics: Adult; Cefepime; Cephalosporins; Chromatography, High Pressure Liquid; Drug Administration Schedule; Drug Evaluation; Half-Life; Humans; Injections, Intravenous; Male | 1992 |
Development of resistance during ceftazidime and cefepime therapy in a murine peritonitis model.
Topics: Animals; Cefepime; Ceftazidime; Cephalosporins; Citrobacter freundii; Disease Models, Animal; Drug Resistance, Microbial; Enterobacter cloacae; Enterobacteriaceae Infections; Female; Mice; Mice, Inbred ICR; Microbial Sensitivity Tests; Peritonitis; Pseudomonas aeruginosa; Pseudomonas Infections; Serratia Infections; Serratia marcescens; Virulence | 1992 |
High-performance liquid chromatographic assays for the quantification of amikacin in human plasma and urine.
Topics: Amikacin; Cefepime; Cephalosporins; Chromatography, High Pressure Liquid; Humans | 1992 |
Peptides related to the carboxyl terminus of human platelet factor IV with antibacterial activity.
Topics: Amino Acid Sequence; Animals; Anti-Bacterial Agents; Aztreonam; Bacterial Infections; Cefepime; Cephalosporins; Drug Design; Drug Therapy, Combination; Escherichia coli; Humans; Klebsiella pneumoniae; Mice; Molecular Sequence Data; Neutropenia; Peptide Fragments; Platelet Factor 4; Protein Conformation; Pseudomonas aeruginosa; Structure-Activity Relationship | 1992 |
Serum concentrations of cefepime (BMY-28142), a broad-spectrum cephalosporin, in dogs.
Topics: Animals; Cefepime; Cephalosporins; Chromatography, High Pressure Liquid; Dogs; Female; Injections, Intramuscular; Injections, Subcutaneous; Male | 1992 |
Selection and characterization of cefepime-resistant gram-negative bacteria.
Topics: Bacterial Outer Membrane Proteins; beta-Lactamases; Cefepime; Cephalosporins; Culture Media; Drug Resistance, Microbial; Electrophoresis, Polyacrylamide Gel; Gram-Negative Bacteria; Microbial Sensitivity Tests; Mutation | 1991 |
Post-antibiotic effect of beta-lactam antibiotics on gram-negative bacteria in relation to morphology, initial killing and MIC.
Topics: Anti-Bacterial Agents; Cefepime; Cefotaxime; Ceftazidime; Cephalosporins; Enterobacteriaceae; Humans; Imipenem; Luminescent Measurements; Microbial Sensitivity Tests; Pseudomonas aeruginosa | 1991 |
Comparison of cefepime, cefpirome, and cefaclidine binding affinities for penicillin-binding proteins in Escherichia coli K-12 and Pseudomonas aeruginosa SC8329.
Topics: Bacterial Proteins; beta-Lactamases; Carrier Proteins; Cefepime; Cefpirome; Cell Membrane; Cephalosporins; Escherichia coli; Hexosyltransferases; Muramoylpentapeptide Carboxypeptidase; Penicillin-Binding Proteins; Peptidyl Transferases; Protein Binding; Pseudomonas aeruginosa | 1991 |
In vitro activities of cefepime alone and with amikacin against aminoglycoside-resistant gram-negative bacteria.
Topics: Amikacin; Anti-Bacterial Agents; Cefepime; Cephalosporins; Drug Interactions; Drug Resistance, Microbial; Gram-Negative Bacteria; Microbial Sensitivity Tests | 1991 |
Dose-proportional pharmacokinetics of cefepime in rats.
Topics: Animals; Cefepime; Cephalosporins; Chromatography, High Pressure Liquid; Female; Male; Rats; Rats, Inbred Strains; Regression Analysis; Spectrophotometry, Ultraviolet | 1991 |
Modulation of the intestinal flora of mice by parenteral treatment with broad-spectrum cephalosporins.
Topics: Animals; Candida albicans; Cecum; Cefepime; Cefoperazone; Ceftazidime; Ceftriaxone; Cephalosporins; Chromatography, High Pressure Liquid; Citrobacter; Feces; Gram-Negative Aerobic Bacteria; Intestines; Mice; Organ Size | 1991 |
Comparative activity of cefepime, alone and in combination, against clinical isolates of Pseudomonas aeruginosa and Pseudomonas cepacia from cystic fibrosis patients.
Topics: Anti-Bacterial Agents; Cefepime; Cephalosporins; Cystic Fibrosis; Humans; Microbial Sensitivity Tests; Pseudomonas; Pseudomonas aeruginosa; Sputum | 1991 |
Beta-lactam antibiotics potentiate magainin 2 antimicrobial activity in vitro and in vivo.
Topics: Animals; Anti-Bacterial Agents; Antimicrobial Cationic Peptides; Bacteria; Bacterial Infections; Cefepime; Cephalosporins; Drug Evaluation, Preclinical; Drug Synergism; Escherichia coli; Magainins; Male; Mice; Microbial Sensitivity Tests; Peptides; Xenopus Proteins | 1991 |
Pharmacodynamics of cefepime.
Topics: Bacteria; Cefepime; Cephalosporins; Humans; Middle Aged; Serum Bactericidal Test | 1990 |
Influence of subinhibitory concentrations of cephalosporins on the serum sensitivity of Pseudomonas aeruginosa.
Topics: Amikacin; Blood Bactericidal Activity; Cefepime; Ceftazidime; Cephalosporins; Ciprofloxacin; Complement C9; Complement System Proteins; Dose-Response Relationship, Drug; Humans; Imipenem; Lipopolysaccharides; Pseudomonas aeruginosa; Serum Bactericidal Test | 1990 |
In vitro activity of cefepime, a new parenteral cephalosporin, against recent European blood isolates and in comparison with piperacillin/tazobactam.
Topics: beta-Lactamase Inhibitors; beta-Lactamases; Cefepime; Cephalosporins; Drug Resistance, Microbial; Drug Synergism; Enterobacteriaceae; Gram-Negative Bacteria; Microbial Sensitivity Tests; Penicillanic Acid; Penicillin Resistance; Piperacillin; Staphylococcus; Tazobactam | 1990 |
Cefepime concentrations in bronchial mucosa and serum following a single 2 gram intravenous dose.
Topics: Biological Assay; Bronchi; Cefepime; Cephalosporins; Escherichia coli; Female; Humans; Injections, Intravenous; Male; Mucous Membrane | 1990 |
Comparative in vitro activity of cefpirome and cefepime, two new cephalosporins.
Topics: Anti-Bacterial Agents; Cefepime; Cefpirome; Cephalosporins; Ciprofloxacin; Enterobacteriaceae; Gentamicins; Microbial Sensitivity Tests | 1990 |
Cefepime for treatment of experimental chronic osteomyelitis due to Staphylococcus aureus.
Topics: Animals; Cefepime; Cephalosporins; Chronic Disease; Disease Models, Animal; Osteomyelitis; Rabbits; Staphylococcal Infections | 1990 |
Pharmacokinetics of cefepime in patients with respiratory tract infections.
Topics: Aged; Aged, 80 and over; Cefepime; Cephalosporins; Female; Humans; Infusions, Intravenous; Male; Metabolic Clearance Rate; Middle Aged; Respiratory Tract Infections | 1990 |
Comparative study of the effects of four cephalosporins against Escherichia coli in vitro and in vivo.
Topics: Animals; Cefepime; Cefoperazone; Ceftazidime; Ceftriaxone; Cephalosporins; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Escherichia coli; Escherichia coli Infections; Female; Mice | 1990 |
Therapeutic studies of cefepime (BMY 28142) in murine meningitis and pharmacokinetics in neonatal rats.
Topics: Animals; Animals, Newborn; Bacteria; Cefepime; Cefotaxime; Cephalosporins; Male; Meningitis; Mice; Microbial Sensitivity Tests; Moxalactam; Rats; Rats, Inbred Strains | 1990 |
Pharmacokinetics of cefepime in subjects with renal insufficiency.
Topics: Adult; Cefepime; Cephalosporins; Creatinine; Drug Administration Schedule; Half-Life; Humans; Infusions, Intravenous; Kidney Failure, Chronic; Male; Mathematics; Metabolic Clearance Rate; Middle Aged; Renal Dialysis | 1990 |
Activity of cefepime against ceftazidime- and cefotaxime-resistant gram-negative bacteria and its relationship to beta-lactamase levels.
Topics: Bacterial Infections; Bacterial Proteins; beta-Lactamases; Cefepime; Cefotaxime; Ceftazidime; Cell Membrane Permeability; Cephalosporins; Drug Resistance, Microbial; Enzyme Induction; Gram-Negative Bacteria; Isoelectric Focusing; Microbial Sensitivity Tests; Pseudomonas aeruginosa; Pseudomonas Infections | 1989 |
In vitro activity of fleroxacin and 6 other antimicrobials against Acinetobacter anitratus.
Topics: Acinetobacter; Anti-Bacterial Agents; Cefepime; Ceftazidime; Ceftriaxone; Cephalosporins; Ciprofloxacin; Enoxacin; Fleroxacin; Humans; Microbial Sensitivity Tests; Ofloxacin; Tobramycin | 1989 |
Comparative in vitro activity of cefepime (BMY 28142) against multiresistant nosocomial isolates of Pseudomonas aeruginosa.
Topics: Anti-Bacterial Agents; Cefepime; Cephalosporins; Cross Infection; Drug Resistance, Microbial; Humans; In Vitro Techniques; Microbial Sensitivity Tests; Pseudomonas aeruginosa | 1989 |
Activity of cefepime, ceftazidime, and ceftizoxime against mutants of Enterobacteriaceae and Pseudomonas aeruginosa derepressed for class I beta-lactamase.
Topics: Cefepime; Ceftazidime; Ceftizoxime; Cephalosporins; Enterobacteriaceae; Enzyme Repression; Microbial Sensitivity Tests; Penicillinase; Pseudomonas aeruginosa | 1989 |
Comparison of the in vitro and in vivo antibacterial activities of cefepime (BMY-28142) with ceftazidime, cefuzonam, cefotaxime and cefmenoxime.
Topics: Animals; Bacteria; Bacterial Infections; beta-Lactamases; Cefepime; Cefmenoxime; Cefotaxime; Ceftazidime; Ceftizoxime; Cephalosporins; Immunosuppression Therapy; Mice; Microbial Sensitivity Tests | 1989 |
Activity of cefepime (BMY-28142) and cefpirome (HR 810) against gram-negative bacilli resistant to cefotaxime or ceftazidime.
Topics: Cefepime; Cefotaxime; Cefpirome; Ceftazidime; Cephalosporins; Drug Resistance, Microbial; Gram-Negative Bacteria | 1989 |
The influence of cefepime on opsonophagocytosis of bacteria.
Topics: Amdinocillin; Bacteria; Cefepime; Ceftriaxone; Cephalosporins; Escherichia coli; Humans; In Vitro Techniques; Leukocytes; Microbial Sensitivity Tests; Opsonin Proteins; Phagocytosis | 1989 |
Comparative in vitro antibacterial activity of the new carbapenem meropenem (SM-7338).
Topics: Anti-Bacterial Agents; Cefepime; Ceftazidime; Cephalosporins; Imipenem; Meropenem; Microbial Sensitivity Tests; Thienamycins; Ticarcillin | 1989 |
Pharmacokinetics and tissue penetration of cefepime.
Topics: Adult; Blister; Body Fluids; Cefepime; Cephalosporins; Half-Life; Humans; Injections, Intravenous; Male | 1989 |
Cephalosporin penetration into soft tissue of paralyzed limbs.
Topics: Animals; Cefepime; Cephalosporins; Chromatography, High Pressure Liquid; Hemoglobins; Hindlimb; Mice; Muscles; Organ Size; Paralysis; Time Factors | 1989 |
The importance of pharmacodynamics in determining the dosing interval in therapy for experimental pseudomonas endocarditis in the rat.
Topics: Animals; Cefepime; Ceftazidime; Cephalosporins; Ciprofloxacin; Drug Therapy, Combination; Endocarditis, Bacterial; Gentamicins; Pseudomonas aeruginosa; Pseudomonas Infections; Quinolines; Rats; Rats, Inbred Strains; Time Factors | 1986 |
In vitro activity of BRL 36650, a new penicillin.
Topics: Acinetobacter; Amikacin; Anti-Bacterial Agents; Aztreonam; Bacteria; Cefepime; Ceftazidime; Cephalosporins; Enterobacteriaceae; Humans; Microbial Sensitivity Tests; Penicillin Resistance; Penicillins; Piperacillin; Pseudomonas; Pseudomonas aeruginosa | 1986 |
In vitro activity of BMY-28142, a new cephalosporin.
Topics: Bacteria; Cefepime; Cefoperazone; Cefotaxime; Ceftazidime; Cephalosporins; Microbial Sensitivity Tests; Pseudomonas aeruginosa; Staphylococcus aureus | 1987 |
Frequency of in vitro resistance of Pseudomonas aeruginosa to cefepime, ceftazidime, and cefotaxime.
Topics: Cefepime; Cefotaxime; Ceftazidime; Cephalosporins; Drug Resistance, Microbial; Pseudomonas aeruginosa; Selection, Genetic | 1988 |
In vitro activity of E-1040, a novel cephalosporin with potent activity against Pseudomonas aeruginosa.
Topics: Aminoglycosides; beta-Lactamases; Cefepime; Cefpirome; Ceftazidime; Cephalosporins; Drug Resistance; Drug Stability; Gentamicins; Hydrolysis; Imipenem; Microbial Sensitivity Tests; Pseudomonas aeruginosa | 1988 |
Toxicity and pharmacokinetics of cefepime (BMY-28142) following intravitreal injection in pigmented rabbit eyes.
Topics: Animals; Aqueous Humor; Cefepime; Cephalosporins; Dose-Response Relationship, Drug; Electroretinography; Eye; Injections; Rabbits; Vitreous Body | 1988 |
Cephalosporinase interactions and antimicrobial activity of BMY-28142, ceftazidime and cefotaxime.
Topics: beta-Lactamases; Cefepime; Cefotaxime; Ceftazidime; Cephalosporinase; Cephalosporins; Citrobacter; Enterobacter; Hydrolysis; Kinetics | 1988 |
In-vitro activity of cefpirome (HR-810), WIN-49375, BMY-28142 and other antibiotics against nosocomially important isolates from cancer patients.
Topics: Anti-Bacterial Agents; Cefepime; Cefpirome; Cephalosporins; Ciprofloxacin; Cross Infection; Fluoroquinolones; Gram-Negative Bacteria; Humans; Imipenem; Microbial Sensitivity Tests; Neoplasms; Quinolines; Thienamycins | 1986 |
Comparative in vitro activities of ampicillin, BMY 28142, and imipenem against Mycobacterium avium complex.
Topics: Ampicillin; Cefepime; Cephalosporins; Humans; Imipenem; Microbial Sensitivity Tests; Mycobacterium avium; Thienamycins | 1987 |
In vitro susceptibility of methicillin-resistant Staphylococcus aureus to imipenem and other antimicrobial agents.
Topics: Amikacin; Anti-Bacterial Agents; Cefepime; Cephalosporins; Clindamycin; Fusidic Acid; Imipenem; Methicillin; Microbial Sensitivity Tests; Norfloxacin; Pefloxacin; Penicillin Resistance; Rifampin; Staphylococcus aureus; Thienamycins; Tobramycin; Vancomycin | 1987 |
The activity of BMY 28142 a new broad spectrum beta-lactamase stable cephalosporin.
Topics: Anti-Bacterial Agents; Bacteria; beta-Lactamases; Cefepime; Cephalosporins; Gram-Negative Aerobic Bacteria; Gram-Negative Anaerobic Bacteria; Gram-Positive Bacteria; Hydrolysis; Microbial Sensitivity Tests; Tobramycin | 1986 |
Affinity of cephalosporins for beta-lactamases as a factor in antibacterial efficacy.
Topics: Bacteria; beta-Lactamases; Cefepime; Ceftazidime; Cephalosporins; Chromatography, High Pressure Liquid; Isoelectric Focusing; Microbial Sensitivity Tests | 1986 |
In vitro activity of carumonam (RO 17-2301), BMY-28142, aztreonam, and ceftazidime against 7,620 consecutive clinical bacterial isolates.
Topics: Anti-Bacterial Agents; Aztreonam; Bacteria; Cefepime; Ceftazidime; Cephalosporins; Citrobacter; Enterobacteriaceae; Humans; Microbial Sensitivity Tests; Pseudomonas | 1986 |
Antibacterial activity of BMY-28142, a novel broad-spectrum cephalosporin.
Topics: Animals; Bacterial Infections; Cefepime; Cefotaxime; Ceftazidime; Cephalosporins; Chemical Phenomena; Chemistry; Male; Mice; Microbial Sensitivity Tests; Penicillin Resistance | 1986 |
High-pressure liquid chromatographic analysis of BMY-28142 in plasma and urine.
Topics: Animals; Blood Proteins; Cefepime; Cephalosporins; Chromatography, High Pressure Liquid; Humans; Kinetics; Protein Binding; Rats; Regression Analysis; Software | 1987 |
Development of beta-lactam-resistant Enterobacter cloacae in mice.
Topics: Animals; Anti-Bacterial Agents; Ascitic Fluid; beta-Lactams; Cefepime; Cephalosporins; Drug Resistance, Microbial; Enterobacter; Enterobacteriaceae; Female; Lactams; Male; Mice; Mice, Inbred ICR | 1987 |
Pharmacokinetics of the novel cephalosporin cefepime (BMY-28142) in rats and monkeys.
Topics: Analysis of Variance; Animals; Cefepime; Cephalosporins; Infusion Pumps; Infusions, Intravenous; Injections, Intravenous; Kinetics; Macaca fascicularis; Male; Rats; Rats, Inbred Strains; Regression Analysis | 1987 |
Comparative in vitro evaluation of BMY-28142, a new broad-spectrum cephalosporin, versus other beta-lactams against multiresistant gram-negative isolates.
Topics: Anti-Bacterial Agents; Cefepime; Cephalosporins; Cross Infection; Drug Resistance, Microbial; Gram-Negative Bacteria; Humans; Microbial Sensitivity Tests | 1987 |
Tentative disk diffusion susceptibility interpretive criteria for BMY-28142, a new cephalosporin.
Topics: Bacteria; Cefepime; Cephalosporins; Drug Resistance, Microbial; Microbial Sensitivity Tests; Regression Analysis | 1986 |
Synthesis and structure-activity relationships of a new series of cephalosporins, BMY-28142 and related compounds.
Topics: Bacteria; Cefepime; Cephalosporins; Structure-Activity Relationship | 1986 |
In vitro studies of BMY-28142, a new broad-spectrum cephalosporin.
Topics: Anti-Bacterial Agents; Bacteria; Cefepime; Cephalosporins; Hydrogen-Ion Concentration; Microbial Sensitivity Tests | 1985 |
New cephalosporins cefotaxime, cefpimizole, BMY 28142, and HR 810 in experimental pneumococcal meningitis in rabbits.
Topics: Animals; Cefepime; Cefotaxime; Cefpirome; Cephalosporins; Meningitis, Pneumococcal; Rabbits; Streptococcus pneumoniae | 1985 |
BMY28142, cefbuperazone (T-1982), and Sch 34343. Antimicrobial activity against 94 anaerobes compared to seven other antimicrobial agents.
Topics: Anti-Bacterial Agents; Bacteroides; Cefepime; Cefoperazone; Cefoxitin; Cephalosporins; Cephamycins; Chloramphenicol; Clindamycin; Clostridium; Lactams; Metronidazole; Microbial Sensitivity Tests; Piperacillin | 1985 |
HR 810 and BMY-28142, two new cephalosporins with broad-spectrum activity: an in-vitro comparison with other beta-lactam antibiotics.
Topics: Anti-Bacterial Agents; Bacteria; Cefepime; Cefpirome; Cephalosporins; Microbial Sensitivity Tests; Species Specificity | 1985 |
In vitro activity of BMY-28142 in comparison with those of other beta-lactam antimicrobial agents.
Topics: Anti-Bacterial Agents; Bacteria; Cefepime; Cephalosporins; Drug Resistance, Microbial; Enterobacteriaceae; Gram-Negative Bacteria; Gram-Positive Bacteria; Microbial Sensitivity Tests | 1985 |
In-vitro activity of BMY 28142, a new aminothiazolyl cephalosporin.
Topics: Acinetobacter; Bacteria; Cefepime; Cephalosporins; Enterobacteriaceae; Methicillin; Microbial Sensitivity Tests; Staphylococcus aureus | 1985 |
In vitro antibacterial activity of BMY-28142, a new extended-spectrum cephalosporin.
Topics: Bacteria; Cefepime; Cephalosporins; Drug Resistance, Microbial; Imipenem; Microbial Sensitivity Tests; Mutation; Thienamycins | 1985 |
Comparison of a new cephalosporin, BMY 28142, with other broad-spectrum beta-lactam antibiotics.
Topics: Animals; Anti-Bacterial Agents; Bacteria; Bacterial Infections; Biological Availability; Blood Proteins; Cefepime; Cefoperazone; Cefotaxime; Ceftazidime; Cephalosporins; Drug Resistance, Microbial; Humans; Male; Mice; Microbial Sensitivity Tests; Moxalactam; Protein Binding | 1985 |
Evaluation of the in vitro activity of BMY-28142, a new broad-spectrum cephalosporin.
Topics: Bacteria; beta-Lactamases; Cefepime; Cefoperazone; Cefotaxime; Cefpirome; Ceftazidime; Cephalosporins; Drug Stability; Hydrolysis; Microbial Sensitivity Tests | 1985 |
Multistrain comparison of three antimicrobial prophylaxis regimens in experimental postoperative Pseudomonas endophthalmitis.
Topics: Animals; Anti-Bacterial Agents; Cefazolin; Cefepime; Ceftazidime; Cephalosporins; Drug Combinations; Drug Evaluation, Preclinical; Eye Diseases; Gentamicins; Inflammation; Postoperative Period; Pseudomonas Infections; Rabbits | 1985 |
Efficacy of BMY-28142 in experimental bacteremia and meningitis caused by Escherichia coli and group B streptococci.
Topics: Animals; Cefepime; Cefotaxime; Cephalosporins; Escherichia coli; Female; Meningitis; Microbial Sensitivity Tests; Penicillin G; Pregnancy; Rats; Rats, Inbred Strains; Sepsis; Streptococcal Infections; Streptococcus agalactiae | 1985 |
In vitro activity of BMY-28142 against pediatric pathogens, including isolates from cystic fibrosis sputum.
Topics: Bacteria; Cefepime; Cephalosporins; Child; Cystic Fibrosis; Drug Interactions; Haemophilus influenzae; Humans; Microbial Sensitivity Tests; Pseudomonas aeruginosa; Sputum; Staphylococcus aureus; Streptococcus pneumoniae | 1985 |
Antimicrobial activities of BMY-28142, cefbuperazone, and cefpiramide compared with those of other cephalosporins.
Topics: Bacteria; Cefepime; Cephalosporins; Cephamycins; Microbial Sensitivity Tests | 1984 |
Activity of cefepime against ceftazidime-resistant gram-negative bacilli using low and high inocula.
Topics: beta-Lactamases; Cefepime; Ceftazidime; Cephalosporin Resistance; Cephalosporins; Enterobacter; Enterobacter cloacae; Gram-Negative Bacteria; Kinetics; Microbial Sensitivity Tests; Pseudomonas aeruginosa | 1995 |
[In vitro activity of six beta-lactams against 295 strains of enterobacteriaceae and P. aeruginosa isolated from neutropenic patients].
Topics: Cefepime; Cefotaxime; Cefpirome; Ceftazidime; Cephalosporins; Drug Resistance, Microbial; Drug Therapy, Combination; Enterobacteriaceae; Humans; Imipenem; In Vitro Techniques; Neutropenia; Penicillanic Acid; Penicillins; Piperacillin; Pseudomonas aeruginosa; Tazobactam; Thienamycins | 1995 |
Multicentre comparative study on the antibacterial activity of FK-037, a new parenteral cephalosporin.
Topics: Aztreonam; Cefepime; Cefotaxime; Cefpirome; Ceftazidime; Ceftizoxime; Cephalosporins; Gram-Negative Bacteria; Gram-Positive Bacteria; Imipenem; Microbial Sensitivity Tests; Sensitivity and Specificity | 1995 |
[Cefepim].
Topics: Bacteria; Cefepime; Cephalosporins; Humans; Infections | 1995 |
beta-Lactamase activity in mycobacteria including Mycobacterium avium and suppression of their growth by a beta-lactamase-stable antibiotic.
Topics: Anti-Bacterial Agents; beta-Lactamase Inhibitors; beta-Lactamases; Cefepime; Cell Division; Cephalosporins; Clavulanic Acid; Clavulanic Acids; Drug Resistance, Microbial; Isoniazid; Microbial Sensitivity Tests; Mycobacterium; Mycobacterium avium; Penicillanic Acid; Streptomycin; Sulbactam; Tazobactam | 1995 |
[Cephalosporins of the 4th generation. Further progress in antibacterial chemotherapy].
Topics: Bacterial Infections; Cefepime; Cefpirome; Cephalosporins; Gram-Negative Aerobic Bacteria; Gram-Positive Bacterial Infections; Humans; Microbial Sensitivity Tests | 1995 |
Antibacterial activity of cefepime in vitro.
Topics: Cefepime; Cephalosporins; Ciprofloxacin; Drug Resistance, Microbial; Gram-Negative Bacteria; Gram-Positive Bacteria; Hospitals, General; Hospitals, Veterans; Humans; Microbial Sensitivity Tests; Taiwan | 1994 |
Comparative antimicrobial activity of FK037, cefpirome, ceftazidime and cefepime against aminoglycoside-sensitive and aminoglycoside-resistant Pseudomonas aeruginosa and Pseudomonas spp.
Topics: Aminoglycosides; Anti-Bacterial Agents; Cefepime; Cefpirome; Ceftazidime; Ceftizoxime; Cephalosporins; Drug Resistance, Microbial; Humans; Microbial Sensitivity Tests; Pseudomonas; Pseudomonas aeruginosa; Species Specificity | 1994 |
Effect of cefepime (BMY-28142) on the hemolytic and bactericidal activity of serum in vivo and in vitro.
Topics: Animals; Blood Bactericidal Activity; Cefepime; Cephalosporins; Complement Pathway, Classical; Hemolysis; Mice; Staphylococcus aureus | 1994 |
Antimicrobial activity of FK-037, a new broad-spectrum cephalosporin. International in vitro comparison with cefepime and ceftazidime.
Topics: Cefepime; Ceftazidime; Ceftizoxime; Cephalosporins; Enterobacteriaceae; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; Microbial Sensitivity Tests | 1994 |
Antimicrobial activity of cefepime tested against Bush group I beta-lactamase-producing strains resistant to ceftazidime. A multilaboratory national and international clinical isolate study.
Topics: beta-Lactamases; Cefepime; Ceftazidime; Cephalosporin Resistance; Cephalosporins; Ciprofloxacin; Cross Infection; Gram-Negative Bacteria; Gram-Negative Bacterial Infections; Humans; Imipenem; International Cooperation; Microbial Sensitivity Tests | 1994 |
Cefepime: part of the new generation.
Topics: Bacteria; Bacterial Infections; beta-Lactamases; Cefepime; Cephalosporins; Drug Resistance, Microbial; Humans | 1994 |
Criteria for use of cefepime in adults. American Society of Hospital Pharmacists.
Topics: Adult; Bacterial Infections; Cefepime; Cephalosporins; Humans | 1994 |
European Study Group on Antibiotic Breakpoints. Breakpoint determination: cefepime.
Topics: Bacterial Infections; Cefepime; Cephalosporins; Drug Resistance, Microbial; Humans; Microbial Sensitivity Tests | 1994 |
The effect of cefepime on some immune parameters in vitro: lack of interference with mitogen-induced lymphoproliferation, immunoglobulin synthesis, IFN-gamma and IL-2 secretion and IL-2 receptor expression.
Topics: Adult; Cefepime; Cephalosporins; Female; Humans; Immunoglobulins; Interferon-gamma; Interleukin-2; Lymphocyte Activation; Male; Receptors, Interleukin-2 | 1993 |
Effect of the cephalosporin cefepime on hepatic drug metabolising enzyme activity in rats.
Topics: 7-Alkoxycoumarin O-Dealkylase; Administration, Oral; Aminopyrine N-Demethylase; Animals; Cefepime; Cephalosporins; Cytochrome P-450 Enzyme System; Enzyme Induction; Female; Liver; Male; Organ Size; Rats; Rats, Sprague-Dawley; Sex Characteristics | 1994 |
Cefepime: a beta-lactamase-stable extended-spectrum cephalosporin.
Topics: Animals; Cefepime; Cephalosporins; Humans | 1993 |
Pharmacokinetics of cefepime in patients with the sepsis syndrome.
Topics: Adult; Aged; Aging; Cefepime; Cephalosporins; Chromatography, High Pressure Liquid; Female; Half-Life; Humans; Male; Sepsis; Spectrophotometry, Ultraviolet | 1993 |
A comparative study of the in-vitro activity of cefepime and other antimicrobial agents against penicillin-susceptible and penicillin-resistant Streptococcus pneumoniae.
Topics: Anti-Bacterial Agents; Cefepime; Cephalosporins; Humans; Microbial Sensitivity Tests; Oxacillin; Penicillin Resistance; Pneumococcal Infections; Streptococcus pneumoniae | 1993 |
In-vitro activities of cefepime against Enterobacter cloacae, Serratia marcescens, Pseudomonas aeruginosa and other aerobic gram-negative bacilli.
Topics: Aminoglycosides; Anti-Bacterial Agents; Aztreonam; Cefepime; Cephalosporins; Doxycycline; Enterobacter cloacae; Gram-Negative Aerobic Bacteria; Gram-Negative Bacterial Infections; Humans; Korea; Penicillins; Pseudomonas aeruginosa; Serratia marcescens | 1993 |
In-vitro activity of cefepime and other antimicrobials: survey of European isolates.
Topics: Anti-Bacterial Agents; Bacteria; Bacterial Infections; Cefepime; Cephalosporins; Europe; Humans; Methicillin Resistance; Microbial Sensitivity Tests; Penicillinase | 1993 |
In-vitro antibacterial activity of cefepime: a multicentre study.
Topics: Bacteria; Bacterial Infections; Cefepime; Cephalosporins; Drug Resistance; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; Microbial Sensitivity Tests | 1993 |
Activity of cefepime and other beta-lactam antibiotics against permeability mutants of Escherichia coli and Klebsiella pneumoniae.
Topics: Anti-Bacterial Agents; Cefepime; Cell Membrane Permeability; Cephalosporins; Drug Resistance, Microbial; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Klebsiella pneumoniae; Microbial Sensitivity Tests; Mutation; Porins | 1993 |
Canadian survey of antimicrobial resistance in Klebsiella spp. and Enterobacter spp. The Canadian Antimicrobial Resistance Study Group.
Topics: Anti-Bacterial Agents; Canada; Cefepime; Cefpirome; Cephalosporins; Drug Resistance, Microbial; Enterobacter; Enterobacteriaceae Infections; Humans; Klebsiella; Klebsiella Infections; Microbial Sensitivity Tests | 1993 |
Efficacy of cefepime in a Staphylococcus aureus endocarditis rat model.
Topics: Animals; Anti-Bacterial Agents; Cefepime; Cephalosporins; Endocarditis, Bacterial; Half-Life; Heart; Male; Microbial Sensitivity Tests; Rats; Rats, Sprague-Dawley; Staphylococcal Infections; Staphylococcus aureus | 1993 |
Multicenter comparison of in vitro activities of FK-037, cefepime, ceftriaxone, ceftazidime, and cefuroxime.
Topics: Anti-Bacterial Agents; Cefepime; Ceftazidime; Ceftizoxime; Ceftriaxone; Cefuroxime; Cephalosporins; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; Microbial Sensitivity Tests | 1993 |
In-vitro activity of cefepime against bacterial pathogens from hospitalized patients.
Topics: Cefepime; Cephalosporins; Cross Infection; Humans; Microbial Sensitivity Tests | 1993 |
A comparative study of the in-vitro activity of cefepime and other cephalosporins.
Topics: Cefepime; Cephalosporins; Enterobacteriaceae; Gram-Negative Bacteria; Humans; Staphylococcus aureus | 1993 |
Effects of beta-lactamase inducibility and derepression on the activity of cefpirome against gram-negative bacteria.
Topics: beta-Lactamases; Cefepime; Cefpirome; Cephalosporins; Enzyme Induction; Gram-Negative Bacteria; Microbial Sensitivity Tests | 1993 |
Ciprofloxacin-induced, low-level resistance to structurally unrelated antibiotics in Pseudomonas aeruginosa and methicillin-resistant Staphylococcus aureus.
Topics: Amikacin; Cefepime; Cephalosporins; Ciprofloxacin; Drug Resistance, Microbial; Fusidic Acid; Gentamicins; Imipenem; Methicillin Resistance; Microbial Sensitivity Tests; Mutation; Pseudomonas aeruginosa; Staphylococcus aureus | 1993 |
Quality control guidelines for cefdinir, cefepime, cefetamet, cefmetazole, cefpodoxime, cefprozil, and clinafloxacin (CI-960) for various National Committee for Clinical Laboratory Standards susceptibility testing methods. Quality Control Study Group.
Topics: Anti-Infective Agents; Cefdinir; Cefepime; Cefmetazole; Cefpodoxime; Cefprozil; Ceftizoxime; Cephalosporins; Fluoroquinolones; Humans; Microbial Sensitivity Tests; Quality Control; Quinolones | 1993 |
Pharmacokinetics of newer cephalosporins after subconjunctival and intravitreal injection in rabbits.
Topics: Animals; Cefepime; Ceftazidime; Ceftizoxime; Ceftriaxone; Cephalosporins; Colony Count, Microbial; Conjunctiva; Disease Models, Animal; Endophthalmitis; Eye Infections, Bacterial; Half-Life; Rabbits; Staphylococcal Infections; Vitreous Body | 1993 |
Simultaneous determination of cefepime and L-arginine in injections by second-derivative spectrophotometry.
Topics: Arginine; Calibration; Cefepime; Cephalosporins; Drug Combinations; Injections; Regression Analysis; Spectrophotometry, Ultraviolet | 1995 |
[Antimicrobial activities of cefepime against clinically isolated strains].
Topics: Bacteria; Bacterial Infections; Cefepime; Cephalosporins; Drug Resistance, Microbial; Humans | 1995 |
Belgian multicentre study on the in vitro activity of cefepime against gram-negative bacilli.
Topics: Anti-Bacterial Agents; Aztreonam; Cefepime; Cephalosporins; Gram-Negative Bacteria; Humans; Microbial Sensitivity Tests; Monobactams; Penicillins; Piperacillin | 1996 |
Differences in the resistant variants of Enterobacter cloacae selected by extended-spectrum cephalosporins.
Topics: Bacterial Outer Membrane Proteins; beta-Lactamases; Cefepime; Ceftazidime; Ceftriaxone; Cephalosporins; Drug Resistance, Microbial; Drug Resistance, Multiple; Enterobacter cloacae; Microbial Sensitivity Tests | 1996 |
[Comparison of four methods for the determination of the susceptibility of 47 strains of Pseudomonas aeruginosa to ceftazidime and cefepime: influence of the choice of interpretative criteria].
Topics: Bacteriological Techniques; Cefepime; Ceftazidime; Cephalosporins; Drug Resistance, Microbial; In Vitro Techniques; Pseudomonas aeruginosa | 1996 |
[Kinetics of bactericidal activity of cefepime and cefpirome alone or combined with gentamicin, amikacin or ciprofloxacin against Acinetobacter baumannii, Stenotrophomonas maltophilia and Enterobacter cloacae hyperproductive in cephalosporinase].
Topics: Acinetobacter; Amikacin; Anti-Bacterial Agents; Anti-Infective Agents; Cefepime; Cefpirome; Cephalosporinase; Cephalosporins; Ciprofloxacin; Dose-Response Relationship, Drug; Drug Therapy, Combination; Enterobacter cloacae; Gentamicins; In Vitro Techniques; Xanthomonas | 1996 |
[Model of a miniature pig catheterized for pharmacokinetic and pharmacodynamic studies of anti-infective agents].
Topics: Adult; Animals; Antibiotics, Antitubercular; Antifungal Agents; Catheterization, Peripheral; Cefepime; Cefpirome; Ceftriaxone; Cephalosporins; Disease Models, Animal; Female; Humans; Injections, Intravenous; Meropenem; Swine; Thienamycins | 1996 |
[In vitro study of antibacterial activity of cefepime (Axepim) against gram negative bacteria: comparison with cephalosporins and other beta-lactams].
Topics: Acinetobacter; Anti-Bacterial Agents; Carbapenems; Cefepime; Cephalosporinase; Cephalosporins; Drug Combinations; Drug Resistance, Microbial; Enterobacteriaceae; Hospital Units; In Vitro Techniques; Monobactams; Pseudomonas aeruginosa | 1996 |
[Practical use of cefepime in an University hospital. Retrospective study of 35 cases].
Topics: Adult; Aged; Aminoglycosides; Anti-Bacterial Agents; Anti-Infective Agents; Cefepime; Cephalosporins; Cross Infection; Drug Therapy, Combination; Female; Fluoroquinolones; Glycopeptides; Hospitals, University; Humans; Injections, Intravenous; Lung Diseases; Male; Middle Aged; Neutropenia; Retrospective Studies; Sepsis | 1996 |
Population pharmacokinetic modeling: the importance of informative graphics.
Topics: Adolescent; Adult; Aged; Cefepime; Cephalosporins; Child; Child, Preschool; Female; Humans; Linear Models; Male; Middle Aged; Models, Biological; Models, Statistical | 1995 |
Cefepime (Maxipime)--a new parenteral cephalosporin.
Topics: Bacterial Infections; Cefepime; Cephalosporins; Drug Costs; Half-Life; Humans; Microbial Sensitivity Tests; Urinary Tract Infections | 1996 |
Activity of cefepime against nosocomial blood culture isolates.
Topics: Bacteremia; Bacteria; Cefepime; Cephalosporins; Cross Infection; Humans; Microbial Sensitivity Tests | 1995 |
Uptake of cefepime by phagocytosing polymorphonuclear neutrophils and subsequent intracellular killing.
Topics: Cefepime; Cephalosporins; Escherichia coli; Humans; Luminescent Measurements; Neutrophil Activation; Neutrophils; Phagocytosis; Staphylococcus aureus | 1996 |
Comparison of three different in vitro methods of detecting synergy: time-kill, checkerboard, and E test.
Topics: Bacteria; Cefepime; Ceftazidime; Cephalosporins; Ciprofloxacin; Drug Synergism; Drug Therapy, Combination; Enterobacter cloacae; Escherichia coli; Microbial Sensitivity Tests; Pseudomonas aeruginosa; Staphylococcus aureus; Tobramycin | 1996 |
Efficacy of cefepime in the treatment of infections due to multiply resistant Enterobacter species.
Topics: beta-Lactam Resistance; Cefepime; Cephalosporins; Enterobacter; Enterobacteriaceae Infections; Europe; Humans; Microbial Sensitivity Tests; United States | 1996 |
Quantitation of cefepime.2HCl dihydrate in cefepime.2HCl monohydrate by diffuse reflectance IR and powder X-ray diffraction techniques.
Topics: Cefepime; Cephalosporins; Microscopy, Electron, Scanning; Particle Size; Powders; Spectroscopy, Fourier Transform Infrared; X-Ray Diffraction | 1996 |
Enhanced susceptibility of Staphylococcus aureus pretreated with cefepime and cefpodoxime to leukocyte activity.
Topics: Blood Bactericidal Activity; Cefepime; Cefpodoxime; Ceftizoxime; Cephalosporins; Humans; Neutrophils; Phagocytosis; Staphylococcus aureus | 1995 |
Cefepime activity against Pseudomonas aeruginosa: evaluation of Etest and two disc diffusion methods.
Topics: Cefepime; Ceftazidime; Cephalosporins; Colony Count, Microbial; Cross Infection; Diffusion; Humans; Microbial Sensitivity Tests; Pseudomonas aeruginosa; Quality Control; Reference Standards; Reproducibility of Results | 1996 |
Cefepime and amikacin synergy against a cefotaxime-susceptible strain of Enterobacter cloacae in vitro and in vivo.
Topics: Amikacin; Animals; Anti-Bacterial Agents; Cefepime; Cefotaxime; Cephalosporins; Drug Resistance, Microbial; Drug Synergism; Enterobacter cloacae; Enterobacteriaceae Infections; Kidney; Male; Microbial Sensitivity Tests; Pneumonia, Bacterial; Rats; Rats, Wistar | 1997 |
The new antibiotics, 1997.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Cefepime; Cephalosporins; Erythromycin; Fluoroquinolones; Humans; Macrolides; Meropenem; Penicillins; Piperacillin; Quinolones; Thienamycins | 1997 |
Hydrolysis of imipenem, meropenem, ceftazidime, and cefepime by multiresistant nosocomial strains of Sphingobacterium multivorum.
Topics: Cefepime; Ceftazidime; Cephalosporins; Cross Infection; Drug Resistance, Microbial; Drug Resistance, Multiple; Flavobacterium; Gram-Negative Bacterial Infections; Humans; Hydrolysis; Imipenem; Meropenem; Microbial Sensitivity Tests; Thienamycins | 1997 |
High-performance liquid chromatographic assay for cefepime in serum.
Topics: Animals; Cefepime; Cephalosporins; Chromatography, High Pressure Liquid; Drug Stability; Humans; Sensitivity and Specificity; Swine; Swine, Miniature | 1997 |
Efficacies of piperacillin-tazobactam and cefepime in rats with experimental intra-abdominal abscesses due to an extended-spectrum beta-lactamase-producing strain of Klebsiella pneumoniae.
Topics: Abdominal Abscess; Animals; beta-Lactamases; Cefepime; Cephalosporins; Drug Therapy, Combination; Enzyme Inhibitors; Klebsiella Infections; Klebsiella pneumoniae; Male; Microbial Sensitivity Tests; Penicillanic Acid; Piperacillin; Rats; Rats, Sprague-Dawley; Tazobactam | 1997 |
Ceftazidime to cefepime formulary switch: pharmacodynamic and pharmacoeconomic rationale.
Topics: Cefepime; Ceftazidime; Cephalosporins; Formularies, Hospital as Topic; Humans; Microbial Sensitivity Tests | 1997 |
[The effect of cefepime on ceftazidime, cefotaxime and imipenem resistant strains of Acinetobacter, Xanthomonas, Pseudomonas, Flavobacterium, Sphingobacterium and on producers of extended spectrum beta-lactamases (ESBL) with resistance transfer].
Topics: Acinetobacter; Bacteria; beta-Lactamases; Cefepime; Cefotaxime; Ceftazidime; Cephalosporins; Drug Resistance, Microbial; Drug Resistance, Multiple; Flavobacterium; Imipenem; Pseudomonas; R Factors; Thienamycins; Xanthomonas | 1997 |
Evaluation of the in vitro activity of cefepime compared to other broad-spectrum cephalosporins against clinical isolates from eighteen Brazilian hospitals by using the Etest.
Topics: Bacteria; Cefepime; Cephalosporins; Drug Resistance, Microbial; Microbial Sensitivity Tests | 1997 |
Pharmacokinetics of intravenously and intramuscularly administered cefepime in infants and children.
Topics: Adolescent; Age Factors; Cefepime; Cephalosporins; Child; Child, Preschool; Female; Humans; Infant; Injections, Intramuscular; Injections, Intravenous; Male | 1997 |
Comparative in vitro susceptibility of Burkholderia Pseudomallei to cefpirome, ceftazidime and cefepime.
Topics: Burkholderia pseudomallei; Cefepime; Cefpirome; Ceftazidime; Cephalosporins; Microbial Sensitivity Tests | 1997 |
Comparison of screening methods for detection of extended-spectrum beta-lactamases and their prevalence among blood isolates of Escherichia coli and Klebsiella spp. in a Belgian teaching hospital.
Topics: Aztreonam; beta-Lactamases; Cefepime; Ceftazidime; Ceftriaxone; Cephalosporins; DNA, Bacterial; Electrophoresis, Gel, Pulsed-Field; Escherichia coli; False Positive Reactions; Klebsiella; Microbial Sensitivity Tests; Monobactams; Sensitivity and Specificity | 1997 |
Synergistic antimycobacterial activity between ethambutol and the beta-lactam drug cefepime.
Topics: Antitubercular Agents; Cefepime; Cephalosporins; Dose-Response Relationship, Drug; Drug Resistance, Microbial; Drug Synergism; Ethambutol; Humans; Microbial Sensitivity Tests; Mycobacterium avium Complex; Mycobacterium tuberculosis; Nontuberculous Mycobacteria | 1997 |
[In vivo pharmacokinetic of amikacin and its pharmacodynamic in combination with cefepime, cefpirome and meropenem in an in vitro/ex vivo micropig model].
Topics: Amikacin; Animals; Anti-Bacterial Agents; Cefepime; Cefpirome; Cephalosporins; Disease Models, Animal; Drug Therapy, Combination; Female; Humans; In Vitro Techniques; Klebsiella pneumoniae; Meropenem; Perfusion; Serum Bactericidal Test; Swine; Thienamycins | 1997 |
[Influence of mechanisms of Pseudomonas aeruginosa resistance on the bactericidal activity of third generation cephalosporins].
Topics: beta-Lactamases; Cefepime; Cephalosporin Resistance; Cephalosporinase; Cephalosporins; In Vitro Techniques; Isoelectric Point; Microbial Sensitivity Tests; Penicillinase; Pseudomonas aeruginosa | 1997 |
Rapid emergence of resistance to cefepime during treatment.
Topics: Cefepime; Cephalosporin Resistance; Cephalosporins; Enterobacter; Enterobacteriaceae Infections; Hepatitis C; Humans; Liver Abscess; Liver Transplantation; Male; Microbial Sensitivity Tests; Middle Aged; Treatment Failure | 1997 |
Relapsing infection due to Enterobacter species: lessons of heterogeneity.
Topics: Abscess; Bacteremia; beta-Lactam Resistance; beta-Lactamases; Cefepime; Cefotaxime; Ceftazidime; Cephalosporin Resistance; Cephalosporins; Drug Resistance, Microbial; Enterobacter; Enterobacteriaceae Infections; Humans; Mutation; Pneumonia, Bacterial | 1997 |
Comparative in vitro activity of cefepime against nosocomial isolates.
Topics: Acinetobacter; beta-Lactamases; Cefepime; Cephalosporins; Cross Infection; Enterobacteriaceae; Greece; Microbial Sensitivity Tests; Penicillin Resistance; Penicillins; Pseudomonas aeruginosa; Staphylococcus aureus | 1997 |
Two cases of possible cefepime-induced neutropenia.
Topics: Adult; Cefepime; Cephalosporins; Female; Humans; Male; Neutropenia; Osteomyelitis; Wound Infection | 1997 |
Susceptibilities of Chryseobacterium indologenes and Chryseobacterium meningosepticum to cefepime and cefpirome.
Topics: Cefepime; Cefpirome; Cephalosporins; Cross Infection; Drug Resistance, Microbial; Flavobacterium; Gram-Negative Bacterial Infections; Humans; In Vitro Techniques; Microbial Sensitivity Tests | 1997 |
Comparison of the effect of cefepime with four cephalosporins against pneumococci with various susceptibilities to penicillin, in vitro and in the mouse peritonitis model.
Topics: Animals; Blood Proteins; Cefepime; Cephalosporins; Half-Life; Mice; Mice, Inbred Strains; Microbial Sensitivity Tests; Penicillin Resistance; Peritonitis; Pneumococcal Infections; Streptococcus pneumoniae; Time Factors | 1997 |
Sporadic emergence of Klebsiella pneumoniae strains resistant to cefepime and cefpirome in Greek hospitals.
Topics: Cefepime; Cefpirome; Cephalosporins; Drug Resistance, Microbial; Humans; Klebsiella pneumoniae; Microbial Sensitivity Tests | 1998 |
Multicenter evaluation of antimicrobial resistance to six broad-spectrum beta-lactams in Colombia using the Etest method. The Colombian Antimicrobial Resistance Study Group.
Topics: Anti-Bacterial Agents; Aztreonam; beta-Lactam Resistance; Cefepime; Cefoperazone; Cefotaxime; Ceftazidime; Cephalosporinase; Cephalosporins; Cohort Studies; Colombia; Enterobacteriaceae; Gram-Negative Bacteria; Humans; Imipenem; Microbial Sensitivity Tests; Reproducibility of Results; Staphylococcus; Sulbactam | 1997 |
In vitro activity of cefepime and ceftazidime against 197 nosocomial blood stream isolates of streptococci: a multicenter sample.
Topics: Anti-Bacterial Agents; Bacteremia; Cefepime; Ceftazidime; Ceftriaxone; Cephalosporins; Cross Infection; Erythromycin; Humans; Penicillins; Streptococcal Infections; Streptococcus; Vancomycin | 1997 |
Activity of cefepime against resistant strains of Pseudomonas aeruginosa.
Topics: beta-Lactam Resistance; Cefepime; Cephalosporins; Imipenem; Microbial Sensitivity Tests; Pseudomonas aeruginosa; Thienamycins | 1997 |
In vitro activity of cefepime and other broad-spectrum beta-lactams tested against 129 mec A-negative Staphylococcus spp. isolates: a multicenter sample.
Topics: Anti-Bacterial Agents; Cefepime; Cephalosporins; Drug Resistance, Microbial; Drug Resistance, Multiple; Genes, Bacterial; Glycopeptides; Humans; Methicillin Resistance; Microbial Sensitivity Tests; Penicillins; Staphylococcal Infections; Staphylococcus | 1998 |
Pharmacokinetics of cefepime and comparison with those of ceftiofur in horses.
Topics: Administration, Oral; Animals; Biological Availability; Cefepime; Cephalosporins; Female; Horses; Injections, Intramuscular; Injections, Intravenous; Male; Metabolic Clearance Rate; Models, Biological | 1998 |
Cefepime and amikacin synergy in vitro and in vivo against a ceftazidime-resistant strain of Enterobacter cloacae.
Topics: Amikacin; Animals; Anti-Bacterial Agents; Cefepime; Ceftazidime; Cephalosporin Resistance; Cephalosporins; Colony Count, Microbial; Creatinine; Disease Models, Animal; Drug Synergism; Drug Therapy, Combination; Enterobacter cloacae; Enterobacteriaceae Infections; Lung; Microbial Sensitivity Tests; Pneumonia, Bacterial; Rats; Rats, Mutant Strains; Time Factors; Treatment Outcome | 1998 |
In-vitro activity of 21 beta-lactam antibiotics against penicillin-susceptible and penicillin-resistant Streptococcus pneumoniae.
Topics: Amoxicillin; Ampicillin; Anti-Bacterial Agents; beta-Lactams; Carbapenems; Cefaclor; Cefadroxil; Cefatrizine; Cefepime; Cefixime; Cefotaxime; Cefpirome; Cefpodoxime; Ceftazidime; Ceftibuten; Ceftizoxime; Ceftriaxone; Cefuroxime; Cephalosporins; Cephradine; Drug Resistance, Microbial; Drug Resistance, Multiple; Humans; Microbial Sensitivity Tests; Penicillin Resistance; Penicillins; Piperacillin; Pneumococcal Infections; Serotyping; Species Specificity; Streptococcus pneumoniae | 1998 |
Comparative in-vitro activity of cefpirome against isolates from intensive care and haematology/oncology units. Belgian Multicentre Study Group.
Topics: beta-Lactam Resistance; Cefepime; Cefpirome; Cephalosporins; Drug Resistance, Microbial; Enterobacteriaceae; Gram-Negative Bacteria; Gram-Positive Cocci; Hematology; Hospital Units; Humans; Intensive Care Units; Microbial Sensitivity Tests; Oncology Service, Hospital | 1998 |
Prospective study of bacteraemia in cancer patients. Results of a French multicentre study.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Bacteremia; Bacteria; Bacteriological Techniques; Cefepime; Cefpirome; Ceftazidime; Cephalosporins; Child; Child, Preschool; Female; Humans; Infant; Male; Microbial Sensitivity Tests; Middle Aged; Neoplasms; Opportunistic Infections; Prospective Studies | 1998 |
In vitro activities of six extended spectrum beta-lactam antibiotics against clinically significant gram-negative bacteria.
Topics: Anti-Bacterial Agents; beta-Lactam Resistance; Cefepime; Cefpirome; Cephalosporins; Gram-Negative Bacteria; Humans; Microbial Sensitivity Tests | 1998 |
Rapid emergence of resistance to cefepime during treatment.
Topics: Cefepime; Cephalosporin Resistance; Cephalosporins; Enterobacter; Enterobacteriaceae Infections; Humans | 1998 |
[Studies on penetration of cefepime into respiratory tract using broncho-alveolar lavage and sputum].
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Bronchoalveolar Lavage Fluid; Cefepime; Cephalosporins; Female; Humans; Male; Middle Aged; Pneumonia, Bacterial; Respiratory System; Sputum | 1997 |
Cefepime-aztreonam: a unique double beta-lactam combination for Pseudomonas aeruginosa.
Topics: Aztreonam; Cefepime; Cephalosporinase; Cephalosporins; Drug Therapy, Combination; Microbial Sensitivity Tests; Monobactams; Mutation; Pseudomonas aeruginosa | 1998 |
[Meningitis caused by Pseudomonas aeruginosa. Treatment with meropenem].
Topics: Aged; Blood-Brain Barrier; Cefepime; Cefotaxime; Cephalosporins; Cerebrospinal Fluid; Cerebrospinal Fluid Shunts; Drug Resistance, Microbial; Drug Therapy, Combination; Humans; Hydrocephalus; Male; Meningitis, Bacterial; Meropenem; Postoperative Complications; Pseudomonas aeruginosa; Pseudomonas Infections; Thienamycins | 1998 |
Activity of cefepime compared with other antibiotics against gram-positive bacteria and cefuroxime-resistant gram-negative bacteria.
Topics: Cefepime; Cefuroxime; Cephalosporin Resistance; Cephalosporins; Gram-Negative Bacteria; Gram-Positive Cocci; Humans; Microbial Sensitivity Tests | 1998 |
A rapid high-performance liquid chromatographic assay for cefepime, cefpirome and meropenem.
Topics: Cefepime; Cefpirome; Cephalosporins; Chromatography, High Pressure Liquid; Humans; Meropenem; Thienamycins | 1998 |
Activities of cefepime and five other antibiotics against nosocomial PER-1-type and/or OXA-10-type beta-lactamase-producing Pseudomonas aeruginosa and Acinetobacter spp.
Topics: Acinetobacter; Acinetobacter Infections; beta-Lactamases; Cefepime; Cephalosporins; Cross Infection; Humans; Microbial Sensitivity Tests; Nucleic Acid Hybridization; Pseudomonas aeruginosa; Pseudomonas Infections; Turkey | 1998 |
Cefepime--assessment of its need at a tertiary care center.
Topics: Adult; Aged; Anti-Infective Agents; Cefepime; Ceftazidime; Cephalosporins; Cilastatin; Ciprofloxacin; Cohort Studies; Drug Utilization Review; Female; Hospitals, University; Humans; Imipenem; Male; Middle Aged; Prospective Studies; Switzerland; Thienamycins | 1998 |
[Comparative study of the bactericidal activity of cefepime and cefpirome in association with glycopeptides against Staphylococci sensitive and resistant to methicillin].
Topics: Anti-Bacterial Agents; Cefepime; Cefpirome; Cephalosporins; Drug Therapy, Combination; Glycopeptides; Methicillin Resistance; Microbial Sensitivity Tests; Staphylococcus | 1998 |
In-vitro activities of cefepime and other beta-lactam antibiotics against clinical isolates from a Colombian teaching hospital.
Topics: Anti-Bacterial Agents; Bacteria; Cefepime; Cephalosporins; Colombia; Cross Infection; Hospitals, Teaching; Humans | 1998 |
Evaluation of the Vitek system to accurately test the susceptibility of Pseudomonas aeruginosa clinical isolates against cefepime.
Topics: Bacteremia; Cefepime; Cephalosporins; Evaluation Studies as Topic; Humans; Microbial Sensitivity Tests; Pneumonia, Bacterial; Pseudomonas aeruginosa; Pseudomonas Infections; Reference Standards; Reproducibility of Results; Sensitivity and Specificity | 1998 |
Efficacies of cefepime, ceftazidime, and imipenem alone or in combination with amikacin in rats with experimental pneumonia due to ceftazidime-susceptible or -resistant Enterobacter cloacae strains.
Topics: Amikacin; Animals; Anti-Bacterial Agents; Cefepime; Ceftazidime; Cephalosporins; Drug Resistance, Microbial; Drug Therapy, Combination; Enterobacter cloacae; Enterobacteriaceae Infections; Imipenem; Injections, Intraperitoneal; Male; Microbial Sensitivity Tests; Pneumonia; Rats; Rats, Wistar; Thienamycins | 1998 |
Evaluation of several dosing regimens of cefepime, with various simulations of renal function, against clinical isolates of Pseudomonas aeruginosa in a pharmacodynamic infection model.
Topics: Cefepime; Cephalosporins; Computer Simulation; Dose-Response Relationship, Drug; Drug Resistance, Microbial; Kidney; Microbial Sensitivity Tests; Models, Biological; Pseudomonas aeruginosa; Time Factors | 1999 |
[Comparative activity of cefepime, ceftazidime and imipenem in a mouse infection caused by Klebsiella pneumoniae producing a broad spectrum beta-lactamase].
Topics: Animals; beta-Lactamases; Cefepime; Ceftazidime; Cephalosporins; Colony Count, Microbial; Imipenem; Klebsiella Infections; Klebsiella pneumoniae; Mice; Microbial Sensitivity Tests; Spleen; Thienamycins | 1998 |
Cefepime versus ceftriaxone for empiric treatment of hospitalized patients with community-acquired pneumonia.
Topics: Cefepime; Ceftriaxone; Cephalosporins; Community-Acquired Infections; Humans; Outcome Assessment, Health Care; Pneumonia | 1999 |
Comparison of ex-vivo serum bactericidal activity of cefepime, ceftazidime and cloxacillin against Staphylococcus aureus.
Topics: Adult; Anti-Bacterial Agents; Cefepime; Ceftazidime; Cephalosporins; Cloxacillin; Female; Humans; Male; Middle Aged; Staphylococcus aureus | 1999 |
Quantitative determination of cefepime in plasma and vitreous fluid by high-performance liquid chromatography.
Topics: Aged; Calibration; Cefepime; Cephalosporins; Chromatography, High Pressure Liquid; Female; Humans; Indicators and Reagents; Reference Standards; Reproducibility of Results; Solutions; Spectrophotometry, Ultraviolet; Vitreous Body | 1999 |
Stability of cefepime hydrochloride injection in polypropylene syringes at -20 degrees C, 4 degrees C, and 22-24 degrees C.
Topics: Cefepime; Cephalosporins; Drug Stability; Drug Storage; Humans; Injections; Polypropylenes; Syringes; Temperature | 1999 |
Influence of pH, temperature and buffers on cefepime degradation kinetics and stability predictions in aqueous solutions.
Topics: Arginine; Buffers; Cefepime; Cephalosporins; Drug Interactions; Drug Stability; Hydrogen-Ion Concentration; Models, Theoretical; Molecular Structure; Solubility; Temperature | 1998 |
Accuracy of cefepime antimicrobial susceptibility testing results for Pseudomonas aeruginosa tested on the MicroScan WalkAway System.
Topics: Cefepime; Cephalosporins; Drug Resistance, Microbial; Evaluation Studies as Topic; Humans; Microbial Sensitivity Tests; Pseudomonas aeruginosa; Reproducibility of Results | 1999 |
[Interview on cefepime].
Topics: Cefepime; Cephalosporins; Humans | 1999 |
Markedly different rates and resistance profiles exhibited by seven commonly used and newer beta-lactams on the selection of resistant variants of Enterobacter cloacae.
Topics: Anti-Bacterial Agents; beta-Lactam Resistance; Cefamandole; Cefepime; Cefoperazone; Ceftazidime; Ceftriaxone; Cephalosporins; Drug Resistance, Microbial; Enterobacter cloacae; Imipenem; Meropenem; Microbial Sensitivity Tests; Thienamycins | 1999 |
Stability of cefepime hydrochloride in polypropylene syringes.
Topics: Anti-Bacterial Agents; Cefepime; Cephalosporins; Drug Packaging; Drug Storage; Humans; Polypropylenes; Syringes; Temperature; Time Factors | 1999 |
Rapid high-performance liquid chromatographic determination of cefepime in human plasma.
Topics: Cefepime; Cephalosporins; Chromatography, High Pressure Liquid; Humans; Reproducibility of Results; Sensitivity and Specificity; Spectrophotometry, Ultraviolet | 1999 |
Treatment of experimental pneumonia in rats caused by a PER-1 extended-spectrum beta-lactamase-producing strain of Pseudomonas aeruginosa.
Topics: Amikacin; Animals; Anti-Bacterial Agents; beta-Lactamases; Cefepime; Cephalosporins; Colony Count, Microbial; Disease Models, Animal; Drug Synergism; Drug Therapy, Combination; Imipenem; Lung; Male; Microbial Sensitivity Tests; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Pneumonia, Bacterial; Pseudomonas aeruginosa; Pseudomonas Infections; Rats; Rats, Wistar | 1999 |
Cefepime-related neurotoxicity in a haemodialysis patient.
Topics: Adult; Cefepime; Cephalosporins; Humans; Male; Nervous System Diseases; Renal Dialysis | 1999 |
Stability of cefepime in peritoneal dialysis solution.
Topics: Cefepime; Cephalosporins; Chromatography, High Pressure Liquid; Dialysis Solutions; Drug Stability; Peritoneal Dialysis; Temperature; Time Factors | 1999 |
Septicemia in neutropenic patients infected with Clostridium tertium resistant to cefepime and other expanded-spectrum cephalosporins.
Topics: Aged; Anti-Bacterial Agents; Cefepime; Cephalosporin Resistance; Cephalosporins; Clostridium; Clostridium Infections; Humans; Male; Middle Aged; Neutropenia; Opportunistic Infections; Sepsis; Vancomycin | 1999 |
Determination of cefepime and cefpirome in human serum by high-performance liquid chromatography using an ultrafiltration for antibiotics serum extraction.
Topics: Cefepime; Cefpirome; Cephalosporins; Chromatography, High Pressure Liquid; Drug Monitoring; Humans; Quality Control; Sensitivity and Specificity; Ultrafiltration | 1999 |
In-vitro activity of cefepime and other broad-spectrum antimicrobials against several groups of gram-negative bacilli and Staphylococcus aureus.
Topics: Cefepime; Cephalosporins; Enterobacteriaceae; Gram-Negative Bacteria; Klebsiella pneumoniae; Microbial Sensitivity Tests; Pseudomonas aeruginosa; Staphylococcus aureus | 1999 |
Evaluation of the in vitro antimicrobial activity of cefepime compared to other broad-spectrum beta-lactams tested against recent clinical isolates from 10 Chinese hospitals. Chinese Antimicrobial Resistance Study Group.
Topics: Anti-Bacterial Agents; Bacteria; beta-Lactamases; Cefepime; Cephalosporins; Enterobacteriaceae; Gram-Negative Bacteria; Humans; Microbial Sensitivity Tests; Staphylococcus | 1999 |
In-vitro activity of cefepime and seven other antimicrobial agents against 1518 non-fermentative Gram-negative bacilli collected from 48 Canadian health care facilities. Canadian Afermenter Study Group.
Topics: Anti-Bacterial Agents; Canada; Cefepime; Cephalosporins; Gram-Negative Bacteria; Humans; Microbial Sensitivity Tests | 1999 |
Comparison of five beta-lactam antibiotics against common nosocomial pathogens using the time above MIC at different creatinine clearances.
Topics: Anti-Bacterial Agents; Bacteria; Cefepime; Ceftazidime; Cephalosporins; Creatinine; Humans; Imipenem; In Vitro Techniques; Microbial Sensitivity Tests; Models, Biological; Penicillanic Acid; Piperacillin; Tazobactam; Time Factors | 1999 |
Evaluation of cefepime alone and in combination with vancomycin against penicillin-resistant pneumococci in the rabbit meningitis model and in vitro.
Topics: Animals; Anti-Bacterial Agents; Cefepime; Ceftriaxone; Cephalosporins; Drug Evaluation, Preclinical; Drug Therapy, Combination; Meningitis, Pneumococcal; Penicillin Resistance; Rabbits; Vancomycin | 2000 |
[The comparative activity of cefepime and other current antibiotics against microorganisms isolated from patients in pediatric intensive therapy units].
Topics: Anti-Bacterial Agents; Cefepime; Cephalosporins; Child; Cross Infection; Dose-Response Relationship, Drug; Gram-Negative Bacteria; Gram-Negative Bacterial Infections; Gram-Positive Bacteria; Gram-Positive Bacterial Infections; Humans; Intensive Care Units, Pediatric; Microbial Sensitivity Tests | 1999 |
beta-lactam antibiotics as substrates for OCTN2, an organic cation/carnitine transporter.
Topics: Acetylcarnitine; Animals; Anti-Bacterial Agents; Carnitine; Carrier Proteins; Cefadroxil; Cefepime; Cephaloridine; Cephalosporins; Dose-Response Relationship, Drug; HeLa Cells; Humans; Kinetics; Membrane Proteins; Nitrogen; Organic Cation Transport Proteins; Rats; Sodium; Solute Carrier Family 22 Member 5; Tumor Cells, Cultured | 2000 |
Substitutions in the eyelet region disrupt cefepime diffusion through the Escherichia coli OmpF channel.
Topics: Anti-Bacterial Agents; Bacterial Proteins; Cefepime; Cephalosporins; Colicins; Escherichia coli; Microbial Sensitivity Tests; Models, Molecular; Mutagenesis; Porins; Protein Folding | 2000 |
In vitro evaluation of cefepime and other broad-spectrum beta-lactams for isolates in Malaysia and Singapore medical centers. The Malaysia/Singapore Antimicrobial Resistance Study Group.
Topics: Acinetobacter; Anti-Bacterial Agents; Bacteria; Cefepime; Cephalosporins; Enterobacteriaceae; Humans; Microbial Sensitivity Tests; Staphylococcus | 1999 |
In vitro evaluation of cefepime and other broad-spectrum beta-lactams against bacteria from Indonesian medical centers. The Indonesia Antimicrobial Resistance Study Group.
Topics: Anti-Bacterial Agents; Bacteria; Cefepime; Cephalosporins; Enterobacteriaceae; Gram-Negative Bacteria; Humans; Microbial Sensitivity Tests; Staphylococcus | 1999 |
In vitro evaluation of broad-spectrum beta-lactams in the philippines medical centers: role of fourth-generation cephalosporins. The Philippines Antimicrobial Resistance Study Group.
Topics: Bacteria; Cefepime; Cephalosporins; Enterobacteriaceae; Gram-Negative Bacteria; Humans; Microbial Sensitivity Tests; Staphylococcus | 1999 |
In vitro evaluation of cefepime and other broad-spectrum beta-lactams in Taiwan medical centers. The Taiwan Antimicrobial Resistance Study Group.
Topics: Anti-Bacterial Agents; Bacteria; Cefepime; Cephalosporins; Enterobacteriaceae; Gram-Negative Bacteria; Humans; Microbial Sensitivity Tests | 1999 |
In vitro evaluation of broad-spectrum beta-lactams tested in medical centers in Korea: role of fourth-generation cephalosporins. The Korean Antimicrobial Resistance Study Group.
Topics: Cefepime; Cephalosporins; Enterobacteriaceae; Gram-Negative Bacteria; Humans; Microbial Sensitivity Tests; Staphylococcus | 1999 |
In vitro evaluation of cefepime and other broad-spectrum beta-lactams in eight medical centers in Thailand. The Thailand Antimicrobial Resistance Study Group.
Topics: Anti-Bacterial Agents; Bacteria; Cefepime; Cephalosporins; Humans; Microbial Sensitivity Tests | 1999 |
Comparison of the activity of two broad-spectrum cephalosporins tested against 2,299 strains of Pseudomonas aeruginosa isolated at 38 North American medical centers participating in the SENTRY Antimicrobial Surveillance Program, 1997-1998.
Topics: Cefepime; Ceftazidime; Cephalosporin Resistance; Cephalosporins; Cross Infection; Databases, Factual; Humans; Microbial Sensitivity Tests; North America; Pseudomonas aeruginosa | 2000 |
Efficacies of imipenem, meropenem, cefepime, and ceftazidime in rats with experimental pneumonia due to a carbapenem-hydrolyzing beta-lactamase-producing strain of Enterobacter cloacae.
Topics: Animals; Anti-Bacterial Agents; Area Under Curve; beta-Lactamases; Carbapenems; Cefepime; Ceftazidime; Cephalosporins; Creatinine; Drug Resistance, Microbial; Enterobacter cloacae; Enterobacteriaceae Infections; Half-Life; Imipenem; Kidney Diseases; Male; Meropenem; Penicillinase; Pneumonia, Bacterial; Protein Binding; Rats; Rats, Wistar; Thienamycins; Uranyl Nitrate | 2000 |
In-vitro activity of FK 037 (Cefoselis), a novel 4(th) generation cephalosporin, compared to cefepime and cefpirome on nosocomial staphylococci and gram-negative isolates.
Topics: Acinetobacter; Cefepime; Cefpirome; Ceftizoxime; Cephalosporins; Cross Infection; Enterobacteriaceae; Gram-Negative Bacteria; Humans; Methicillin Resistance; Microbial Sensitivity Tests; Pseudomonas; Staphylococcus aureus; Stenotrophomonas | 2000 |
Efficacy of cefepime and amikacin in the empiric treatment of febrile neutropenic children with cancer.
Topics: Adolescent; Amikacin; Anti-Bacterial Agents; Bacteremia; Cefepime; Cephalosporins; Child; Child, Preschool; Drug Therapy, Combination; Escherichia coli Infections; Female; Fever; Fever of Unknown Origin; Humans; Infant; Male; Neoplasms; Neutropenia; Staphylococcal Infections; Streptococcal Infections; Treatment Outcome | 2000 |
In vitro activity of cefepime and cefotaxime compared to six other agents against 350 penicillin-susceptible and penicillin-resistant Streptococcus pneumoniae.
Topics: Anti-Bacterial Agents; Cefepime; Cefotaxime; Cephalosporins; Humans; Microbial Sensitivity Tests; Penicillin Resistance; Streptococcal Infections; Streptococcus pneumoniae | 2000 |
Comparative aspects of the diffusion of norfloxacin, cefepime and spermine through the F porin channel of Enterobacter cloacae.
Topics: Binding, Competitive; Biological Transport; Cefepime; Cephalosporins; Drug Interactions; Enterobacter cloacae; Microbial Sensitivity Tests; Norfloxacin; Porins; Spermine | 2000 |
Comparative in vitro bactericidal activity between cefepime and ceftazidime, alone and associated with amikacin, against carbapenem-resistant Pseudomonas aeruginosa strains.
Topics: Amikacin; Anti-Bacterial Agents; Carbapenems; Cefepime; Ceftazidime; Cephalosporins; Drug Resistance, Microbial; Microbial Sensitivity Tests; Pseudomonas aeruginosa | 2000 |
Outbreak of Klebsiella pneumoniae producing transferable AmpC-type beta-lactamase (ACC-1) originating from Hafnia alvei.
Topics: Amino Acid Sequence; Aztreonam; Bacterial Proteins; Base Sequence; beta-Lactamases; Cefepime; Cefotaxime; Cefoxitin; Ceftazidime; Ceftriaxone; Cephalosporins; Cephamycins; Cloning, Molecular; Cross Infection; Disease Outbreaks; Drug Resistance, Microbial; Electrophoresis, Gel, Pulsed-Field; France; Hafnia; Humans; Klebsiella Infections; Klebsiella pneumoniae; Microbial Sensitivity Tests; Molecular Sequence Data; Monobactams; Plasmids; Polymerase Chain Reaction | 2000 |
In vitro activity of meropenem, imipenem, cefepime and ceftazidime against Pseudomonas aeruginosa isolates from cystic fibrosis patients.
Topics: Carbapenems; Cefepime; Ceftazidime; Cephalosporins; Cystic Fibrosis; Humans; Imipenem; Meropenem; Microbial Sensitivity Tests; Pseudomonas aeruginosa; Thienamycins | 2000 |
Status epilepticus associated with cefepime.
Topics: Adult; Cefepime; Cephalosporins; Electroencephalography; Female; Humans; Male; Pseudomonas Infections; Status Epilepticus | 2000 |
Multiple-dose pharmacokinetics of cefepime in long-term hemodialysis with high-flux membranes.
Topics: Adult; Cefepime; Cephalosporins; Communicable Diseases; Female; Humans; Kidney Failure, Chronic; Male; Middle Aged; Renal Dialysis | 2000 |
In vitro efficacy of six cephalosporins tested against Enterobacteriaceae isolated at 38 North American medical centres participating in the SENTRY Antimicrobial Surveillance Program, 1997-1998.
Topics: beta-Lactamases; Cefepime; Cephalosporins; Citrobacter; Drug Resistance, Microbial; Enterobacter; Enterobacteriaceae; Escherichia coli; Humans; Klebsiella pneumoniae; Microbial Sensitivity Tests; Multicenter Studies as Topic; North America; Serratia marcescens; Species Specificity | 2000 |
Quinupristin-dalfopristin combined with beta-lactams for treatment of experimental endocarditis due to Staphylococcus aureus constitutively resistant to macrolide-lincosamide-streptogramin B antibiotics.
Topics: Animals; Anti-Bacterial Agents; Cefamandole; Cefepime; Cephalosporins; Disease Models, Animal; Drug Resistance, Microbial; Drug Resistance, Multiple; Drug Therapy, Combination; Endocarditis, Bacterial; Humans; Lincosamides; Macrolides; Microbial Sensitivity Tests; Rats; Staphylococcal Infections; Staphylococcus aureus; Time Factors; Virginiamycin | 2000 |
Efficacy and safety of cefepime in the treatment of serious bacterial infections in hospitalized adult patients.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Bacterial Infections; Cefepime; Cephalosporins; Female; Hospitalization; Humans; Male; Middle Aged | 2000 |
Comparison of the MICs of cefepime for extended-spectrum beta-lactamase-producing and non-extended-spectrum beta-lactamase-producing strains of Enterobacter cloacae.
Topics: beta-Lactamases; Cefepime; Cephalosporins; Enterobacter cloacae; Microbial Sensitivity Tests | 2000 |
[Antibiotic sensitivity of enterobacteria in intensive care units].
Topics: Ascitic Fluid; Blood; Catheterization; Cefepime; Cefotaxime; Cefpirome; Ceftazidime; Cephalosporin Resistance; Cephalosporins; Drug Resistance, Microbial; Enterobacteriaceae; France; Humans; Intensive Care Units; Microbial Sensitivity Tests; Respiratory System; Urine | 2000 |
Evaluation of antibiotic synergy against Acinetobacter baumannii: a comparison with Etest, time-kill, and checkerboard methods.
Topics: Acinetobacter; Acinetobacter Infections; Anti-Bacterial Agents; Anti-Infective Agents; Cefepime; Cephalosporins; Drug Synergism; Drug Therapy, Combination; Fluoroquinolones; Humans; Microbial Sensitivity Tests; Naphthyridines; Penicillins; Piperacillin; Reproducibility of Results; Tobramycin | 2000 |
Synergistic effect of cefepime on the phagocytic killing of Staphylococcus aureus by human polymorphonuclear leucocytes and the determination of this effect by means of nitrite production.
Topics: Cefepime; Cephalosporins; Drug Synergism; Humans; Neutrophils; Nitrites; Phagocytosis; Staphylococcus aureus | 2000 |
[Hafnia alvei septicemia revealing pyocholecystitis complicated by liver abscess in an immunocompetent patient].
Topics: Acute Disease; Aged; Bacteremia; Cefepime; Cephalosporins; Cholangiography; Cholangiopancreatography, Endoscopic Retrograde; Cholecystectomy; Cholecystitis; Enterobacteriaceae Infections; Gentamicins; Hafnia alvei; Humans; Liver Abscess; Male; Netilmicin; Suppuration; Treatment Outcome | 2000 |
Cerebral manifestations of cefepime toxicity in a dialysis patient.
Topics: Aged; Brain Diseases; Cefepime; Cephalosporins; Dialysis; Electroencephalography; Female; Humans; Renal Insufficiency | 2000 |
Successful use of recombinant tissue plasminogen activator in a patient with relapsing peritonitis.
Topics: Adult; Cefepime; Cephalosporins; Ciprofloxacin; Drug Therapy, Combination; Gentamicins; Humans; Injections, Intraperitoneal; Male; Peritoneal Dialysis, Continuous Ambulatory; Peritonitis; Recombinant Proteins; Recurrence; Remission Induction; Tissue Plasminogen Activator; Vancomycin | 2001 |
In vitro synergy between cefepime and vancomycin against methicillin-susceptible and -resistant Staphylococcus aureus and Staphylococcus epidermidis.
Topics: Anti-Bacterial Agents; Cefepime; Cephalosporins; Drug Synergism; Humans; Methicillin Resistance; Microbial Sensitivity Tests; Staphylococcus aureus; Staphylococcus epidermidis; Time Factors; Vancomycin | 2001 |
Extension of resistance to cefepime and cefpirome associated to a six amino acid deletion in the H-10 helix of the cephalosporinase of an Enterobacter cloacae clinical isolate.
Topics: Amino Acid Sequence; Bacterial Proteins; Base Sequence; beta-Lactamases; Cefepime; Cefpirome; Cephalosporin Resistance; Cephalosporinase; Cephalosporins; Child; Cloning, Molecular; Enterobacter cloacae; Enterobacteriaceae Infections; Escherichia coli; Genes, Bacterial; Humans; Kinetics; Microbial Sensitivity Tests; Molecular Sequence Data; Protein Structure, Secondary; Recombinant Proteins; Sequence Deletion | 2001 |
Severe but reversible encephalopathy associated with cefepime.
Topics: Aged; Aged, 80 and over; Bacterial Infections; Cefepime; Cephalosporins; Confusion; Creatinine; Electroencephalography; Female; Hallucinations; Humans; Kidney Diseases; Male; Middle Aged; Myoclonus | 2000 |
[Comparative antibacterial activity of cefotaxime, ceftazidime and cefepime with regard to different strains of Enterobacter aerogenes selected for their resistance to third generation cephalosporins].
Topics: beta-Lactamases; Cefepime; Cefotaxime; Ceftazidime; Cephalosporins; Drug Resistance, Microbial; Enterobacter aerogenes | 2000 |
[Comparative studies of treatments with cefepime and ceftazidime in patients with pneumonia].
Topics: Cefepime; Ceftazidime; Cephalosporins; Female; Humans; Male; Middle Aged; Pneumonia | 2000 |
Prediction of gram-negative bacteremia in patients with cancer and febrile neutropenia by means of interleukin-8 levels in serum: targeting empirical monotherapy versus combination therapy.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Bacteremia; Cefepime; Cephalosporins; Drug Therapy, Combination; Fever; Gentamicins; Gram-Negative Bacterial Infections; Humans; Interleukin-8; Leukemia; Lymphoma; Male; Middle Aged; Netilmicin; Neutropenia; Predictive Value of Tests; Prospective Studies | 2001 |
[Combination effect of teicoplanin and beta-lactams on MRSA].
Topics: Anti-Bacterial Agents; Cefepime; Cefmetazole; Cephalosporins; Cephamycins; Drug Synergism; Methicillin Resistance; Microbial Sensitivity Tests; Staphylococcus aureus; Teicoplanin; Thienamycins | 2000 |
Comparative activities of isepamicin, amikacin, cefepime, and ciprofloxacin alone or in combination with other antibiotics against Stenotrophomonas maltophilia.
Topics: Amikacin; Anti-Bacterial Agents; Anti-Infective Agents; Cefepime; Cephalosporins; Ciprofloxacin; Colony Count, Microbial; Drug Resistance, Bacterial; Drug Resistance, Multiple, Bacterial; Drug Synergism; Drug Therapy, Combination; Gentamicins; Gram-Negative Bacterial Infections; Microbial Sensitivity Tests; Stenotrophomonas maltophilia; Time Factors | 2001 |
In vitro and in vivo activities of amikacin, cefepime, amikacin plus cefepime, and imipenem against an SHV-5 extended-spectrum beta-lactamase-producing Klebsiella pneumoniae strain.
Topics: Amikacin; Animals; beta-Lactam Resistance; beta-Lactamases; Cefepime; Cephalosporins; Drug Therapy, Combination; Imipenem; Kinetics; Klebsiella Infections; Klebsiella pneumoniae; Mice; Microbial Sensitivity Tests; Survival Analysis | 2001 |
Multicentre study of the in vitro activity of cefepime, a broad-spectrum cephalosporin, compared to other broad-spectrum agents.
Topics: Cefepime; Cephalosporins; Drug Resistance, Microbial; Gram-Negative Bacteria; Gram-Positive Bacteria; In Vitro Techniques; Microbial Sensitivity Tests | 2001 |
Abiotrophia bacteremia in a patient with neutropenic fever and antimicrobial susceptibility testing of Abiotrophia isolates.
Topics: Anti-Bacterial Agents; Bacteremia; Cefepime; Cephalosporins; Drug Resistance, Microbial; Fever; Gram-Positive Bacterial Infections; Humans; Levofloxacin; Male; Microbial Sensitivity Tests; Middle Aged; Neutropenia; Ofloxacin; Streptococcaceae | 2001 |
[Activity of cefepime compared with other antibiotics against major hospital bacterial pathogens].
Topics: Anti-Bacterial Agents; Bacterial Infections; Cefepime; Cephalosporins; Cross Infection; Drug Resistance, Microbial; Humans; Microbial Sensitivity Tests | 2001 |
Efficacy of gatifloxacin alone and in combination with cefepime against penicillin-resistant Streptococcus pneumoniae in a rabbit meningitis model and in vitro.
Topics: Animals; Anti-Infective Agents; Cefepime; Cephalosporins; Disease Models, Animal; Drug Therapy, Combination; Fluoroquinolones; Gatifloxacin; Meningitis, Bacterial; Microbial Sensitivity Tests; Penicillin Resistance; Rabbits; Streptococcus pneumoniae; Treatment Outcome | 2001 |
[Combination effect of arbekacin and cefepime on mixed culture of MRSA and P. aeruginosa].
Topics: Aminoglycosides; Anti-Bacterial Agents; Cefepime; Cephalosporins; Dibekacin; Drug Synergism; Drug Therapy, Combination; Humans; Methicillin Resistance; Pseudomonas aeruginosa; Staphylococcus aureus; Teicoplanin; Time Factors; Vancomycin | 2001 |
High-performance liquid chromatographic determination of cefepime in human plasma and in urine and dialysis fluid using a column-switching technique.
Topics: Calibration; Cefepime; Cephalosporins; Chromatography, High Pressure Liquid; Dialysis Solutions; Drug Stability; Humans; Quality Control; Reference Standards; Renal Dialysis; Reproducibility of Results; Time Factors | 2001 |
Neuropsychiatric symptoms during cefepime treatment.
Topics: Adult; Cefepime; Cephalosporins; Female; Humans; Kidney Diseases; Male; Mental Disorders; Middle Aged; Netherlands | 2001 |
Oxacillinase-mediated resistance to cefepime and susceptibility to ceftazidime in Pseudomonas aeruginosa.
Topics: beta-Lactamases; Cefepime; Ceftazidime; Cephalosporins; Drug Resistance, Microbial; Humans; Infant; Microbial Sensitivity Tests; Phenotype; Pseudomonas aeruginosa | 2001 |
Determination and pharmacokinetic study of unbound cefepime in rat bile by liquid chromatography with on-line microdialysis.
Topics: Animals; Area Under Curve; Bile; Cefepime; Cephalosporins; Chromatography, High Pressure Liquid; Male; Microdialysis; Rats; Rats, Sprague-Dawley; Spectrophotometry, Ultraviolet | 2001 |
Nosocomial outbreak due to a multiresistant strain of Pseudomonas aeruginosa P12: efficacy of cefepime-amikacin therapy and analysis of beta-lactam resistance.
Topics: Adult; Amikacin; Bacterial Outer Membrane Proteins; beta-Lactam Resistance; beta-Lactamases; beta-Lactams; Cefepime; Cephalosporins; Cross Infection; Disease Outbreaks; Drug Resistance, Microbial; Drug Resistance, Multiple; Drug Therapy, Combination; Humans; Microbial Sensitivity Tests; Polymerase Chain Reaction; Pseudomonas aeruginosa; Pseudomonas Infections; Ribotyping | 2001 |
Efficiency of cefepime in postoperative meningitis attributable to Enterobacter aerogenes.
Topics: Adolescent; Arnold-Chiari Malformation; Cefepime; Cephalosporins; Enterobacter aerogenes; Enterobacteriaceae Infections; Humans; Meningitis, Bacterial; Neurosurgical Procedures; Postoperative Complications | 2001 |
Comparative in vitro antimicrobial activity of a new carbapenem, E1010, and tentative disc diffusion test interpretative criteria.
Topics: Anti-Bacterial Agents; Carbapenems; Cefepime; Cephalosporins; Diffusion; Enterobacteriaceae; Imipenem; Meropenem; Microbial Sensitivity Tests; Pyrrolidines; Thienamycins | 2001 |
The effects of cefephim, G-CSF, and sucralfate on bacterial translocation in experimentally induced acute pancreatitis.
Topics: Acute Disease; Animals; Bacterial Translocation; Cefepime; Cephalosporins; Gastrointestinal Agents; Granulocyte Colony-Stimulating Factor; Liver; Lymph Nodes; Male; Pancreas; Pancreatitis; Rats; Rats, Wistar; Spleen; Sucralfate | 2001 |
Effect of cyclosporine, a P-glycoprotein inhibitor, on the pharmacokinetics of cefepime in rat blood and brain: a microdialysis study.
Topics: Animals; Area Under Curve; ATP Binding Cassette Transporter, Subfamily B, Member 1; Brain; Cefepime; Cephalosporins; Chromatography, High Pressure Liquid; Cyclosporine; Drug Interactions; Immunosuppressive Agents; Male; Microdialysis; Rats; Rats, Sprague-Dawley; Time Factors | 2001 |
Comparison of cefepime pharmacokinetics in neonatal foals and adult dogs.
Topics: Animals; Animals, Newborn; Body Weight; Cefepime; Cephalosporins; Chromatography, High Pressure Liquid; Dogs; Female; Horses; Injections, Intravenous; Male | 2001 |
Efficacy of cefepime versus ceftazidime in the treatment of adult pneumonia.
Topics: Adult; Aged; Cefepime; Ceftazidime; Cephalosporins; Community-Acquired Infections; Cross Infection; Drug Resistance, Bacterial; Female; Humans; Male; Middle Aged; Pneumonia, Bacterial | 2001 |
Cefepime in vitro activity against derepressed extended-spectrum beta-lactamase (ESBL)-producing and non-ESBL-producing Enterobacter cloacae by a disc diffusion method.
Topics: Bacteriological Techniques; beta-Lactamases; Cefepime; Cephalosporins; Enterobacter cloacae; Humans | 2001 |
Nonconvulsive status epilepticus associated with cephalosporins in patients with renal failure.
Topics: Adult; Aged; Aged, 80 and over; Brain; Cefepime; Ceftazidime; Ceftriaxone; Cephalosporins; Electroencephalography; Female; Humans; Infusions, Intravenous; Male; Meningitis, Bacterial; Middle Aged; Osteomyelitis; Renal Insufficiency; Respiratory Tract Infections; Status Epilepticus | 2001 |
The effectiveness of systemic antibiotics in preventing postoperative, intraabdominal adhesions in an animal model.
Topics: Animals; Anti-Infective Agents; Cefepime; Cephalosporins; Fibrosis; Injections, Intramuscular; Metronidazole; Peritoneal Diseases; Postoperative Complications; Rats; Rats, Wistar; Severity of Illness Index; Tissue Adhesions | 2001 |
Cefepime, piperacillin-tazobactam, and the inoculum effect in tests with extended-spectrum beta-lactamase-producing Enterobacteriaceae.
Topics: Anti-Bacterial Agents; Bacterial Proteins; beta-Lactamase Inhibitors; beta-Lactamases; Cefepime; Cephalosporins; Chromosomes, Bacterial; Drug Resistance, Microbial; Enterobacteriaceae; Enzyme Inhibitors; Escherichia coli; Microbial Sensitivity Tests; Penicillanic Acid; Penicillins; Piperacillin; Tazobactam | 2001 |
Susceptibility of pseudomonas aeruginosa to cefepime versus ceftazidime in patients with cystic fibrosis.
Topics: Adolescent; Adult; Cefepime; Ceftazidime; Cephalosporins; Chi-Square Distribution; Child; Child, Preschool; Cystic Fibrosis; Drug Resistance, Bacterial; Female; Humans; Infant; Male; Microbial Sensitivity Tests; Middle Aged; Prospective Studies; Pseudomonas aeruginosa | 2001 |
[Antimicrobial activities of carbapenems and fourth generation cephems against clinically isolated strains].
Topics: Bacteria; Carbapenems; Cefepime; Cefozopran; Cephalosporins; Imipenem; Meropenem; Thienamycins | 2001 |
Severe neurotoxicity of cefepime in uremic patients.
Topics: Aphasia; Cefepime; Cephalosporins; Confusion; Humans; Neurotoxicity Syndromes; Renal Dialysis; Tremor | 2001 |
Effect of inoculum size on the antibacterial activity of cefpirome and cefepime against Klebsiella pneumoniae strains producing SHV extended-spectrum beta-lactamases.
Topics: beta-Lactamases; Cefepime; Cefpirome; Cephalosporins; Colony Count, Microbial; Drug Resistance, Bacterial; Humans; Klebsiella pneumoniae; Microbial Sensitivity Tests | 2001 |
Invasive pulmonary aspergillosis in a puerperant with drug-induced agranulocytosis.
Topics: Adult; Agranulocytosis; Aspergillosis; Aspergillus fumigatus; Cefepime; Cephalosporins; Female; Humans; Lung Diseases, Fungal; Pregnancy; Puerperal Infection; Ritodrine; Severity of Illness Index; Tocolytic Agents | 2001 |
Application of the IDSA guidelines for the use of antimicrobial agents in neutropenic patients: impact on reducing the use of glycopeptides.
Topics: Adolescent; Adult; Aged; Amikacin; Anti-Bacterial Agents; Brazil; Cefepime; Ceftazidime; Cephalosporins; Child; Drug Therapy, Combination; Female; Fever; Hospitals, Teaching; Humans; Male; Middle Aged; Neutropenia; Oxacillin; Practice Guidelines as Topic; Teicoplanin; Treatment Outcome; Vancomycin | 2001 |
[Multicenter evaluation of the antimicrobial activity in vitro for six broad-spectrum beta-lactams in China using the E-test method].
Topics: Anti-Bacterial Agents; Bacteria; beta-Lactams; Cefepime; Cefoperazone; Ceftazidime; Ceftriaxone; Cephalosporins; China; Imipenem; Microbial Sensitivity Tests; Piperacillin | 2000 |
In vitro activity of meropenem and four other antibiotics against 554 clinical strains obtained from Beijing in 1999.
Topics: Anti-Bacterial Agents; Cefepime; Cefoperazone; Ceftazidime; Cephalosporins; Enterobacteriaceae; Humans; Imipenem; Meropenem; Thienamycins | 2000 |
Cefepime is efficacious against penicillin- and quinolone-resistant pneumococci in experimental meningitis.
Topics: 4-Quinolones; Animals; Anti-Infective Agents; Cefepime; Cephalosporins; Disease Models, Animal; Drug Evaluation, Preclinical; Drug Therapy, Combination; Humans; Meningitis, Pneumococcal; Microbial Sensitivity Tests; Penicillin Resistance; Rabbits; Streptococcus pneumoniae | 2002 |
Clinical evaluation of the Vitek automated system with cards GNS 122 and 127 and VTK-R07.01 software for antimicrobial susceptibility testing of Pseudomonas aeruginosa.
Topics: Automation; Cefepime; Cephalosporins; Electronic Data Processing; Humans; Microbial Sensitivity Tests; Penicillins; Piperacillin; Prospective Studies; Pseudomonas aeruginosa; Software; Ticarcillin | 2002 |
Nonconvulsive status epilepticus in dialysis patients.
Topics: Cefepime; Cephalosporins; Electroencephalography; Humans; Peritoneal Dialysis; Status Epilepticus; Uremia | 2002 |
[Activity of new fluoroquinolones against clinical isolates of Acinetobacter baumannii].
Topics: Acinetobacter; Acinetobacter Infections; Ampicillin; Anti-Infective Agents; Aza Compounds; Cefepime; Cephalosporins; Ciprofloxacin; Colistin; Fluoroquinolones; Gatifloxacin; Humans; Imipenem; Meropenem; Microbial Sensitivity Tests; Moxifloxacin; Nalidixic Acid; Naphthyridines; Norfloxacin; Ofloxacin; Opportunistic Infections; Quinolines; Sulbactam; Thienamycins | 2001 |
[Experience in using the fourth generation cephalosporin cefepime (maxipime) in treating Russian patients with severe infections].
Topics: Bacterial Infections; Cefepime; Cephalosporins; Humans; Russia; Treatment Outcome | 2001 |
Penetration of meropenem and cefepim into pancreatic tissue during the course of experimental acute pancreatitis.
Topics: Animals; Anti-Bacterial Agents; Cefepime; Cephalosporins; Ceruletide; Chromatography, High Pressure Liquid; Glycodeoxycholic Acid; Male; Meropenem; Pancreas; Pancreatitis, Acute Necrotizing; Rats; Rats, Sprague-Dawley; Thienamycins | 2002 |
Cefepime-induced neurotoxicity: an underestimated complication of antibiotherapy in patients with acute renal failure.
Topics: Acute Kidney Injury; Adolescent; Aged; Cefepime; Cephalosporins; Chromatography, High Pressure Liquid; Critical Care; Female; Humans; Male; Nervous System; Renal Dialysis | 2002 |
Alteration of pore properties of Escherichia coli OmpF induced by mutation of key residues in anti-loop 3 region.
Topics: Arginine; Cefepime; Cephalosporins; Diffusion; Escherichia coli; Escherichia coli Proteins; Ion Channel Gating; Lipid Bilayers; Lysine; Models, Molecular; Mutagenesis, Site-Directed; Porins; Structure-Activity Relationship | 2002 |
Cefepime MIC as a predictor of the extended-spectrum beta-lactamase type in Klebsiella pneumoniae, Taiwan.
Topics: beta-Lactamases; Cefepime; Cephalosporins; Drug Resistance, Multiple, Bacterial; Humans; Klebsiella pneumoniae; Microbial Sensitivity Tests; Phenotype; Taiwan | 2002 |
Mutational replacement of Leu-293 in the class C Enterobacter cloacae P99 beta-lactamase confers increased MIC of cefepime.
Topics: beta-Lactamases; Cefepime; Cephalosporin Resistance; Cephalosporins; Cloning, Molecular; Enterobacter cloacae; Kinetics; Leucine; Microbial Sensitivity Tests; Models, Molecular; Molecular Conformation; Mutagenesis, Site-Directed; Mutation; Plasmids | 2002 |
Extended-spectrum beta-lactamase-producing Escherichia coli and Klebsiella species: risk factors for colonization and impact of antimicrobial formulary interventions on colonization prevalence.
Topics: Academic Medical Centers; Adult; Aged; Aged, 80 and over; Ampicillin; Anti-Bacterial Agents; beta-Lactam Resistance; Carrier State; Case-Control Studies; Cefepime; Cephalosporins; Cross Infection; Drug Therapy, Combination; Drug Utilization Review; Escherichia coli Infections; Feces; Female; Formularies, Hospital as Topic; Gentamicins; Hospitals, Community; Hospitals, Urban; Humans; Infection Control; Klebsiella Infections; Length of Stay; Male; Middle Aged; Pennsylvania; Prevalence; Risk Factors; Sulbactam | 2002 |
Klebsiella pneumoniae brain abscess in a Taiwanese adult.
Topics: Acyclovir; Brain Abscess; Cefepime; Cephalosporins; Ethnicity; Humans; Klebsiella Infections; Klebsiella pneumoniae; Male; Middle Aged; Taiwan; Vancomycin | 2002 |
Geographic variations in activity of broad-spectrum beta-lactams against Pseudomonas aeruginosa: summary of the worldwide SENTRY Antimicrobial Surveillance Program (1997-2000).
Topics: Aminoglycosides; Anti-Bacterial Agents; Anti-Infective Agents; beta-Lactams; Cefepime; Ceftazidime; Cephalosporins; Fluoroquinolones; Global Health; Humans; Population Surveillance; Pseudomonas aeruginosa; Pseudomonas Infections | 2002 |
Emerging antimicrobial resistances among Proteus mirabilis in Europe: report from the MYSTIC Program (1997-2001). Meropenem Yearly Susceptibility Test Information Collection.
Topics: Anti-Bacterial Agents; Cefepime; Ceftazidime; Cephalosporins; Ciprofloxacin; Critical Care; Cystic Fibrosis; Data Collection; Drug Resistance, Bacterial; Europe; Humans; Imipenem; Meropenem; Microbial Sensitivity Tests; Neutropenia; Penicillanic Acid; Piperacillin; Population Surveillance; Proteus Infections; Proteus mirabilis; Tazobactam; Thienamycins | 2002 |
In vitro activities of quinupristin-dalfopristin and cefepime, alone and in combination with various antimicrobials, against multidrug-resistant staphylococci and enterococci in an in vitro pharmacodynamic model.
Topics: Anti-Bacterial Agents; Cefepime; Cephalosporins; Drug Resistance, Microbial; Drug Resistance, Multiple; Drug Therapy, Combination; Enterococcus; Half-Life; Methicillin Resistance; Microbial Sensitivity Tests; Models, Biological; Staphylococcus; Vancomycin Resistance; Virginiamycin | 2002 |
Pharmacodynamics of cefepime in patients with Gram-negative infections.
Topics: Anti-Bacterial Agents; Cefepime; Cephalosporins; Female; Gram-Negative Bacteria; Gram-Negative Bacterial Infections; Hospitals, University; Hospitals, Urban; Humans; Male; Microbial Sensitivity Tests; Middle Aged; Prospective Studies; Regression Analysis; Treatment Outcome; United States | 2002 |
The efficacy of prophylactic outpatient antibiotics for the prevention of neutropenic fever associated with high-dose etoposide (VP-16) for stem cell mobilization.
Topics: Ambulatory Care; Antibiotic Prophylaxis; Cefepime; Cephalosporins; Ciprofloxacin; Clarithromycin; Data Collection; Drug Therapy, Combination; Etoposide; Female; Fever; Hematopoietic Stem Cell Mobilization; Humans; Male; Middle Aged; Neutropenia; Opportunistic Infections; Vancomycin | 2002 |
Antimicrobial susceptibility of major pathogens of orofacial odontogenic infections to 11 beta-lactam antibiotics.
Topics: Anti-Bacterial Agents; Bacteria; Bacterial Infections; Bacteroidaceae Infections; beta-Lactams; Cefepime; Cefmetazole; Cefoperazone; Cefpirome; Ceftazidime; Ceftizoxime; Cephalosporins; Drug Resistance, Bacterial; Drug Therapy, Combination; Fusobacterium; Fusobacterium Infections; Gram-Positive Bacterial Infections; Humans; Imipenem; Lactams; Microbial Sensitivity Tests; Mouth Diseases; Penicillin G; Penicillins; Peptostreptococcus; Porphyromonas gingivalis; Prevotella; Streptococcal Infections; Streptococcus; Sulbactam | 2002 |
Cefepime, piperacillin/tazobactam, gentamicin, ciprofloxacin, and levofloxacin alone and in combination against Pseudomonas aeruginosa.
Topics: Cefepime; Cephalosporins; Ciprofloxacin; Drug Resistance, Microbial; Drug Therapy, Combination; Gentamicins; Humans; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Penicillanic Acid; Piperacillin; Pseudomonas aeruginosa; Sensitivity and Specificity; Tazobactam | 2002 |
Pitfalls in cefepime titration from human plasma: plasma- and temperature-related drug degradation in vitro.
Topics: Cefepime; Cephalosporins; Chromatography, High Pressure Liquid; Humans; In Vitro Techniques; Reproducibility of Results; Temperature; Ultrafiltration | 2002 |
Surgical antibiotic prophylaxis in a Turkish university hospital.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Ampicillin; Anti-Bacterial Agents; Antibiotic Prophylaxis; Cefazolin; Cefepime; Cephalosporins; Child; Child, Preschool; Female; Hospitals, University; Humans; Infant; Infant, Newborn; Male; Middle Aged; Penicillins; Perioperative Care; Prospective Studies; Sulbactam; Surgical Procedures, Operative; Surgical Wound Infection; Turkey | 2002 |
Clinical and bacteriological results from the administration of Cefepime (Maxipime) in patients with severe sepsis.
Topics: Adult; Aged; Anti-Bacterial Agents; Bacteria; Cefepime; Cephalosporins; Female; Humans; Male; Middle Aged; Sepsis; Treatment Outcome | 2002 |
A comparison of antibiotic regimens in the treatment of acute melioidosis in a mouse model.
Topics: Acute Disease; Animals; Anti-Bacterial Agents; Anti-Infective Agents; Cefepime; Ceftazidime; Cephalosporins; Disease Models, Animal; Drug Therapy, Combination; Injections, Intraperitoneal; Melioidosis; Mice; Mice, Inbred BALB C; Trimethoprim, Sulfamethoxazole Drug Combination | 2003 |
Sustained activity and spectrum of selected extended-spectrum beta-lactams (carbapenems and cefepime) against Enterobacter spp. and ESBL-producing Klebsiella spp.: report from the SENTRY antimicrobial surveillance program (USA, 1997-2000).
Topics: beta-Lactam Resistance; beta-Lactamases; Carbapenems; Cefepime; Cephalosporins; Enterobacter; Klebsiella; Microbial Sensitivity Tests | 2003 |
Cefepime use in a pediatric intensive care unit reduces colonization with resistant bacilli.
Topics: Anti-Bacterial Agents; Cefepime; Cephalosporins; Child; Child, Preschool; Colony Count, Microbial; Cross Infection; Drug Resistance, Microbial; Female; Gram-Negative Bacteria; Gram-Negative Bacterial Infections; Humans; Intensive Care Units, Pediatric; Male; Microbial Sensitivity Tests; Sensitivity and Specificity | 2003 |
Cefepime tissue penetration in experimental acute pancreatitis.
Topics: Animals; Bacteria; Cefepime; Cephalosporins; Ceruletide; Dose-Response Relationship, Drug; Female; Lung; Pancreas; Pancreatitis, Acute Necrotizing; Rats; Rats, Wistar; Time Factors; Tissue Distribution | 2003 |
Stability and compatibility study of cefepime in comparison with ceftazidime for potential administration by continuous infusion under conditions pertinent to ambulatory treatment of cystic fibrosis patients and to administration in intensive care units.
Topics: Ambulatory Care; Cefepime; Ceftazidime; Cephalosporins; Chemical Precipitation; Cystic Fibrosis; Drug Incompatibility; Drug Stability; Drug Storage; Drug Therapy, Combination; Infusions, Intravenous; Intensive Care Units | 2003 |
Integration of population pharmacokinetics, a pharmacodynamic target, and microbiologic surveillance data to generate a rational empiric dosing strategy for cefepime against Pseudomonas aeruginosa.
Topics: Cefepime; Cephalosporins; Dose-Response Relationship, Drug; Female; Half-Life; Humans; Infusions, Intravenous; Male; Metabolic Clearance Rate; Microbial Sensitivity Tests; Population Surveillance; Pseudomonas aeruginosa; Pseudomonas Infections; Retrospective Studies | 2003 |
Disposition of cefepime in the central nervous system of patients with external ventricular drains.
Topics: Adult; Aged; Area Under Curve; Cefepime; Central Nervous System; Cephalosporins; Female; Humans; Male; Microbial Sensitivity Tests; Middle Aged; Models, Biological; Prospective Studies | 2003 |
Determination of the dissociation constants of the cephalosporins cefepime and cefpirome using UV spectrometry and pH potentiometry.
Topics: Cefepime; Cefpirome; Cephalosporins; Hydrogen-Ion Concentration; Potentiometry; Spectrophotometry, Ultraviolet | 2003 |
Pancreatic concentrations of cefepime in experimental necrotizing pancreatitis.
Topics: Animals; Antimetabolites; Cefepime; Cephalosporins; Disease Models, Animal; Dose-Response Relationship, Drug; Ethionine; Injections, Intramuscular; Male; Pancreatitis, Acute Necrotizing; Rabbits; Tissue Distribution | 2003 |
In vitro activity of gatifloxacin alone and in combination with cefepime, meropenem, piperacillin and gentamicin against multidrug-resistant organisms.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Bacteria; Cefepime; Cephalosporins; Drug Combinations; Drug Resistance, Multiple, Bacterial; Drug Synergism; Fluoroquinolones; Gatifloxacin; Gentamicins; Meropenem; Microbial Sensitivity Tests; Penicillins; Piperacillin; Thienamycins | 2003 |
Experimental prediction of the natural evolution of antibiotic resistance.
Topics: beta-Lactamases; Biological Evolution; Cefepime; Cephalosporins; Drug Resistance | 2003 |
Pharmacokinetics-pharmacodynamics of cefepime and piperacillin-tazobactam against Escherichia coli and Klebsiella pneumoniae strains producing extended-spectrum beta-lactamases: report from the ARREST program.
Topics: beta-Lactamases; Cefepime; Cephalosporins; Drug Therapy, Combination; Escherichia coli; Humans; Klebsiella pneumoniae; Microbial Sensitivity Tests; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Probability | 2003 |
Experimental prediction of the evolution of cefepime resistance from the CMY-2 AmpC beta-lactamase.
Topics: Bacterial Proteins; beta-Lactamases; Cefepime; Cephalosporin Resistance; Cephalosporins; Directed Molecular Evolution; Escherichia coli | 2003 |
Pharmacokinetics and pharmacodynamics of cefepime in patients with various degrees of renal function.
Topics: Adult; Aged; Anti-Bacterial Agents; Cefepime; Cephalosporins; Computer Simulation; Female; Humans; Male; Microbial Sensitivity Tests; Middle Aged; Monte Carlo Method; Prospective Studies; Pseudomonas aeruginosa; Renal Insufficiency | 2003 |
Stability and antibacterial activity of cefepime during continuous infusion.
Topics: Anti-Bacterial Agents; Cefepime; Cephalosporins; Drug Stability; Drug Storage; Infusion Pumps; Infusions, Intravenous; Microbial Sensitivity Tests; Pseudomonas aeruginosa | 2003 |
Determination of the frequency of inadequate antibiotic therapy using calculation of indication failure (IF), cumulative indication failure (CIF), and balanced indication failure (BIF).
Topics: Anti-Bacterial Agents; Bacterial Infections; Cefepime; Ceftazidime; Cephalosporins; Cross Infection; Drug Resistance, Multiple; Empiricism; Enterobacteriaceae Infections; Humans; Imipenem; Microbial Sensitivity Tests; Pneumonia, Bacterial; Treatment Failure | 2003 |
Stability of cefepime hydrochloride in AutoDose Infusion System bags.
Topics: Cefepime; Cephalosporins; Drug Stability; Infusion Pumps | 2003 |
Neurotoxicity induced by Cefepime in a very old hemodialysis patient.
Topics: Aged; Cefepime; Cephalosporins; Confusion; Epilepsy, Tonic-Clonic; Humans; Kidney Failure, Chronic; Male; Pneumonia; Renal Dialysis | 2003 |
[Evaluation of a E-test method to detect bactericidy of beta lactam-aminoglycoside associations against Pseudomonas aeruginosa isolates from cystic fibrosis].
Topics: Amikacin; Anti-Bacterial Agents; Cefepime; Ceftazidime; Cephalosporins; Cystic Fibrosis; Drug Therapy, Combination; Humans; Microbial Sensitivity Tests; Pseudomonas aeruginosa; Pseudomonas Infections; Tobramycin | 2003 |
[Cefepime-amikacin combination in febrile neutropenic children with malignant hemopathy or tumor].
Topics: Adolescent; Adult; Amikacin; Anti-Bacterial Agents; Antineoplastic Agents; Bacterial Infections; Cefepime; Cephalosporins; Child; Child, Preschool; Drug Therapy, Combination; Fever; Hematologic Neoplasms; Humans; Infant; Neoplasms; Neutropenia; Patient Selection; Prognosis; Retrospective Studies; Time Factors; Treatment Outcome | 2003 |
Decreased susceptibility to cefepime in a clinical strain of Escherichia coli related to plasmid- and integron-encoded OXA-30 beta-lactamase.
Topics: Aged; beta-Lactamases; Cefepime; Cephalosporins; Drug Resistance, Bacterial; Escherichia coli; Escherichia coli Infections; Humans; Integrons; Plasmids | 2003 |
[Meningitis caused by multiresistant E. coli after an echo-directed transrectal biopsy].
Topics: Aged; Amoxicillin; Biopsy; Brain Damage, Chronic; Cefepime; Cephalosporins; Ciprofloxacin; Clavulanic Acid; Confusion; Drug Resistance, Multiple, Bacterial; Drug Therapy, Combination; Escherichia coli; Escherichia coli Infections; Gentamicins; Humans; Male; Meningitis, Bacterial; Premedication; Prostate; Rectum; Ultrasonography; Vancomycin | 2003 |
Adsorptive stripping voltammetric determination of cefepime at the mercury electrode in human urine and cerebrospinal fluid, and differential pulse polarographic determination in serum.
Topics: Anti-Bacterial Agents; Cefepime; Cephalosporins; Electrochemistry; Electrodes; Humans; Mercury; Polarography; Serum | 2003 |
Post-exposure effects of cefepime and cefpirome on isogenic Escherichia coli hosts producing SHV-extended-spectrum beta-lactamases.
Topics: Anti-Bacterial Agents; beta-Lactamases; Cefepime; Cefpirome; Cephalosporins; Colony Count, Microbial; Drug Resistance, Bacterial; Escherichia coli; Humans; Microbial Sensitivity Tests | 2003 |
Antimicrobial spectrum of activity for meropenem and nine broad spectrum antimicrobials: report from the MYSTIC Program (2002) in North America.
Topics: Anti-Bacterial Agents; Aztreonam; Cefepime; Cephalosporins; Ciprofloxacin; Drug Resistance, Bacterial; Drug Resistance, Multiple; Female; Gentamicins; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; Male; Meropenem; Microbial Sensitivity Tests; North America; Sensitivity and Specificity; Thienamycins; Tobramycin | 2003 |
Steady-state plasma and intrapulmonary concentrations of cefepime administered in continuous infusion in critically ill patients with severe nosocomial pneumonia.
Topics: Aged; Bronchoalveolar Lavage; Cefepime; Cephalosporins; Chromatography, High Pressure Liquid; Cross Infection; Female; Gram-Negative Bacteria; Gram-Positive Bacteria; Hospitals, University; Humans; Infusions, Intravenous; Intensive Care Units; Male; Microbial Sensitivity Tests; Pneumonia, Bacterial; Prospective Studies; Respiratory Mucosa | 2003 |
Antibiotic tissue concentrations revisited in lungs.
Topics: Cefepime; Cephalosporins; Humans; Infusions, Intravenous; Lung; Pneumonia, Bacterial | 2003 |
Lack of efflux mechanism in a clinical isolate of Pseudomonas aeruginosa highly resistant to beta-lactams and imipenem.
Topics: Anti-Bacterial Agents; Bacterial Outer Membrane Proteins; Biological Transport, Active; Cefepime; Ceftazidime; Ceftriaxone; Cell Membrane Permeability; Cephalosporins; Conjugation, Genetic; Cystic Fibrosis; Drug Resistance, Multiple, Bacterial; Electrophoresis, Polyacrylamide Gel; Genes, Bacterial; Humans; Imipenem; Membrane Transport Proteins; Microbial Sensitivity Tests; Porins; Pseudomonas aeruginosa | 2003 |
[Yearly changes in antibacterial activities of cefozopran against various clinical isolates between 1996 and 2001--I. Gram-positive bacteria].
Topics: Cefepime; Cefozopran; Cephalosporins; Gram-Positive Bacteria; Humans; Methicillin Resistance; Microbial Sensitivity Tests; Staphylococcus; Staphylococcus aureus | 2003 |
[Yearly changes in antibacterial activities of cefozopran against various clinical isolates between 1996 and 2001--II. Gram-negative bacteria].
Topics: Cefepime; Cefoperazone; Cefozopran; Cefpirome; Cephalosporins; Drug Resistance, Bacterial; Escherichia coli; Gram-Negative Bacteria; Humans; Moraxella | 2003 |
Neutropenia in patients receiving long-term cefepime therapy for osteomyelitis.
Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; Cefepime; Cephalosporins; Drug Administration Schedule; Female; Humans; Male; Middle Aged; Neutropenia; Osteomyelitis | 2003 |
A simple and sensitive GC method for determination of N-methylpyrrolidine in cefepime and its preparation.
Topics: Cefepime; Cephalosporins; Chromatography, Gas; Pyrrolidines | 2003 |
[The present and the future of cefepime, a 4th generation cephalosporin].
Topics: beta-Lactamases; Cefepime; Cephalosporins; Gram-Negative Bacteria; Hydrolysis | 2003 |
[Comparative in vitro activity of cefepime and other antibiotics against clinical strains of gram-negative bacteria].
Topics: Anti-Bacterial Agents; Cardiology Service, Hospital; Cefepime; Cephalosporins; Gram-Negative Aerobic Bacteria; Humans; Intensive Care Units; Microbial Sensitivity Tests; Surgery Department, Hospital | 2003 |
[Cefepime (maxipime) in the treatment of severe urinary tract infection].
Topics: Adolescent; Adult; Aged; Amikacin; Anti-Bacterial Agents; Cefepime; Cephalosporins; Ciprofloxacin; Drug Administration Schedule; Gram-Negative Bacteria; Gram-Positive Cocci; Humans; Microbial Sensitivity Tests; Middle Aged; Ofloxacin; Sensitivity and Specificity; Treatment Outcome; Urinary Tract Infections | 2003 |
In vitro activity of combination therapy with cefepime, piperacillin-tazobactam, or meropenem with ciprofloxacin against multidrug-resistant Pseudomonas aeruginosa strains.
Topics: Anti-Bacterial Agents; Cefepime; Cephalosporins; Drug Interactions; Drug Resistance, Multiple; Drug Therapy, Combination; Humans; Lactams; Meropenem; Microbial Sensitivity Tests; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Pseudomonas aeruginosa; Pseudomonas Infections; Thienamycins | 2003 |
Nonconvulsive status epilepticus associated with cefepime in a patient undergoing autologous stem cell transplantation.
Topics: Aged; Cefepime; Cephalosporins; Epilepsy; Hodgkin Disease; Humans; Male; Peripheral Blood Stem Cell Transplantation; Staphylococcal Infections; Staphylococcus aureus; Transplantation, Autologous | 2004 |
Pharmacodynamics of S-3578, a novel cephem, in murine lung and systemic infection models.
Topics: Animals; Area Under Curve; Cefepime; Cephalosporins; Colony Count, Microbial; Female; Injections, Subcutaneous; Lung; Methicillin Resistance; Mice; Mice, Inbred CBA; Mice, Inbred ICR; Microbial Sensitivity Tests; Pneumonia, Pneumococcal; Sepsis; Staphylococcal Infections; Staphylococcus aureus; Survival Analysis; Tissue Distribution | 2004 |
A case of IgE-mediated hypersensitivity to cefepime.
Topics: Anaphylaxis; Cefepime; Cephalosporins; Child; Drug Hypersensitivity; Humans; Hypersensitivity, Immediate; Male | 2004 |
Resistance to cefepime and cefpirome due to a 4-amino-acid deletion in the chromosome-encoded AmpC beta-lactamase of a Serratia marcescens clinical isolate.
Topics: Amino Acid Sequence; Bacterial Proteins; beta-Lactamases; Cefepime; Cefpirome; Cephalosporin Resistance; Cephalosporinase; Cephalosporins; Chromosomes, Bacterial; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Hydrolysis; Kinetics; Microbial Sensitivity Tests; Molecular Sequence Data; Mutation; Plasmids; Sequence Deletion; Serratia Infections; Serratia marcescens | 2004 |
Selection during cefepime treatment of a new cephalosporinase variant with extended-spectrum resistance to cefepime in an Enterobacter aerogenes clinical isolate.
Topics: Amino Acid Sequence; Amino Acid Substitution; Cefepime; Cephalosporinase; Cephalosporins; Electrophoresis, Gel, Pulsed-Field; Enterobacter aerogenes; Enterobacteriaceae Infections; Genes, Bacterial; Kinetics; Molecular Sequence Data | 2004 |
Synergistic activities of moxifloxacin combined with piperacillin-tazobactam or cefepime against Klebsiella pneumoniae, Enterobacter cloacae, and Acinetobacter baumannii clinical isolates.
Topics: Acinetobacter baumannii; Acinetobacter Infections; Anti-Infective Agents; Aza Compounds; Cefepime; Cephalosporins; Colony Count, Microbial; Drug Synergism; Enterobacter cloacae; Enterobacteriaceae Infections; Enzyme Inhibitors; Fluoroquinolones; Humans; Klebsiella Infections; Klebsiella pneumoniae; Moxifloxacin; Penicillanic Acid; Penicillins; Piperacillin; Quinolines; Tazobactam | 2004 |
Reversible coma secondary to cefepime neurotoxicity.
Topics: Acute Kidney Injury; Aged; Anti-Bacterial Agents; Cefepime; Cephalosporins; Coma; Dose-Response Relationship, Drug; Electroencephalography; Female; Humans; Neurotoxicity Syndromes | 2004 |
Cefepime-induced non-convulsive status epilepticus in a peritoneal dialysis patient.
Topics: Adolescent; Cefepime; Cephalosporins; Diagnosis, Differential; Electroencephalography; Humans; Kidney Failure, Chronic; Male; Peritoneal Dialysis, Continuous Ambulatory; Status Epilepticus | 2004 |
In vitro effects of some antibiotics on glutathione reductase from sheep liver.
Topics: Animals; Anti-Bacterial Agents; Cefazolin; Cefepime; Cephalosporins; Gentamicins; Glutathione Reductase; In Vitro Techniques; Levofloxacin; Liver; Ofloxacin; Sheep; Thiamphenicol | 2003 |
Resistance to imipenem, cefepime, and cefpirome associated with mutation in Omp36 osmoporin of Enterobacter aerogenes.
Topics: Bacterial Outer Membrane Proteins; Base Sequence; Cefepime; Cefpirome; Cephalosporins; DNA Primers; Drug Resistance, Microbial; Enterobacter aerogenes; Imipenem; Mutation | 2004 |
Exploring the effectiveness of tazobactam against ceftazidime resistant Escherichia coli: insights from the comparison between susceptibility testing and beta-lactamase inhibition.
Topics: Anti-Bacterial Agents; Bacterial Proteins; beta-Lactamase Inhibitors; beta-Lactamases; beta-Lactams; Cefepime; Ceftazidime; Cephalosporins; Drug Resistance, Bacterial; Drug Therapy, Combination; Enzyme Inhibitors; Ertapenem; Escherichia coli; Escherichia coli Infections; Lactams; Microbial Sensitivity Tests; Penicillanic Acid; Tazobactam | 2004 |
Comparison of the double-disk, combined disk, and Etest methods for detecting metallo-beta-lactamases in gram-negative bacilli.
Topics: Anti-Bacterial Agents; Bacteriological Techniques; beta-Lactamases; Cefepime; Ceftazidime; Cephalosporins; Clavulanic Acid; Culture Media, Conditioned; Drug Resistance, Bacterial; Gram-Negative Bacteria; Humans; Imipenem; Microbial Sensitivity Tests; Sensitivity and Specificity | 2004 |
In vitro killing of parenteral beta-lactams against standard and high inocula of extended-spectrum beta-lactamase and non-ESBL producing Klebsiella pneumoniae.
Topics: Anti-Bacterial Agents; beta-Lactamases; beta-Lactams; Cefepime; Cephalosporins; Culture Media, Conditioned; Drug Resistance, Bacterial; Humans; In Vitro Techniques; Klebsiella pneumoniae; Meropenem; Microbial Sensitivity Tests; Penicillanic Acid; Piperacillin; Sensitivity and Specificity; Tazobactam; Thienamycins | 2004 |
Evaluation of a new cefepime-clavulanate ESBL Etest to detect extended-spectrum beta-lactamases in an Enterobacteriaceae strain collection.
Topics: Anti-Bacterial Agents; beta-Lactamase Inhibitors; beta-Lactamases; Cefepime; Cephalosporins; Clavulanic Acid; Drug Resistance, Bacterial; Enterobacter; Enterobacteriaceae; Enterobacteriaceae Infections; Humans; Klebsiella Infections; Klebsiella oxytoca; Phenotype | 2004 |
Determination of the in vivo pharmacodynamic profile of cefepime against extended-spectrum-beta-lactamase-producing Escherichia coli at various inocula.
Topics: Animals; beta-Lactamases; Cefepime; Cephalosporin Resistance; Cephalosporins; Colony Count, Microbial; Escherichia coli; Escherichia coli Infections; Male; Mice; Mice, Inbred ICR; Microbial Sensitivity Tests; Muscle, Skeletal; Thigh | 2004 |
[3-Year experience of use of cefepime (Maxipime) for the treatment of hospital infections in a specialized surgical hospital].
Topics: Anti-Bacterial Agents; Cefepime; Cephalosporins; Cross Infection; Gram-Negative Bacteria; Humans; Neoplasms | 2004 |
Determination of cefepime in plasma and cerebrospinal fluid by micellar electrokinetic chromatography with direct sample injection.
Topics: Cefepime; Cephalosporins; Chromatography, Micellar Electrokinetic Capillary; Humans; Meningitis | 2004 |
In vitro activities of beta-lactam antibiotics alone and in combination with sulbactam against Gram-negative bacteria.
Topics: Acinetobacter baumannii; Ampicillin; Anti-Bacterial Agents; Aztreonam; beta-Lactams; Cefepime; Cefoperazone; Cefotaxime; Ceftazidime; Cephalosporins; Drug Combinations; Drug Resistance, Bacterial; Enterobacter cloacae; Enzyme Inhibitors; Gram-Negative Bacteria; Humans; Imipenem; Klebsiella pneumoniae; Microbial Sensitivity Tests; Serratia marcescens; Sulbactam | 2004 |
Retrospective study of clinical outcomes with extended-spectrum beta-lactamases--a different interpretation.
Topics: Anti-Bacterial Agents; Bacterial Infections; beta-Lactamases; Carbapenems; Cefepime; Cephalosporins; Humans; Retrospective Studies; Time Factors; Treatment Outcome | 2004 |
Monotherapy versus dual therapy based on risk categorization of febrile neutropenic patients.
Topics: Amikacin; Anti-Bacterial Agents; Cefepime; Cephalosporins; Drug Therapy, Combination; Fever; Hematologic Diseases; Humans; Immunocompromised Host; Neutropenia; Opportunistic Infections; Risk Assessment; Sepsis | 2004 |
In vitro activities of antibiotic combinations against clincal isolates of Pseudomonas aeruginosa.
Topics: Amikacin; Anti-Bacterial Agents; Aztreonam; Cefepime; Cephalosporins; Ciprofloxacin; Drug Resistance, Bacterial; Drug Synergism; Humans; Microbial Sensitivity Tests; Piperacillin; Pseudomonas aeruginosa; Taiwan | 2004 |
High prevalence of extended-spectrum beta-lactamase-producing strains among blood isolates of Enterobacter spp. collected in a tertiary hospital during an 8-year period and their antimicrobial susceptibility patterns.
Topics: Anti-Infective Agents; beta-Lactamase Inhibitors; beta-Lactamases; Cefepime; Cephalosporin Resistance; Cephalosporins; Cross Infection; Enterobacter; Enterobacteriaceae Infections; Enzyme Inhibitors; Gene Frequency; Genes, Bacterial; Humans; Isoelectric Focusing; Microbial Sensitivity Tests; Mutation | 2004 |
Comparison of 99mTc-DTPA and urea for measuring cefepime concentrations in epithelial lining fluid.
Topics: Analysis of Variance; Animals; Biological Availability; Biological Transport, Active; Bronchoalveolar Lavage Fluid; Cefepime; Cephalosporins; Disease Models, Animal; Dogs; Epithelium; Female; Infusions, Intravenous; Male; Pneumonia; Radiopharmaceuticals; Sensitivity and Specificity; Technetium Tc 99m Pentetate; Urea | 2004 |
Antimicrobial susceptibility survey of Pseudomonas aeruginosa strains isolated from clinical sources.
Topics: Anti-Bacterial Agents; Cefepime; Cephalosporins; Drug Resistance, Microbial; Humans; Microbial Sensitivity Tests; Pseudomonas aeruginosa | 2004 |
Comparison of in vivo intrinsic activity of cefepime and imipenem in a Pseudomonas aeruginosa rabbit endocarditis model: effect of combination with tobramycin simulating human serum pharmacokinetics.
Topics: Animals; Anti-Bacterial Agents; Cefepime; Cephalosporins; Disease Models, Animal; Drug Therapy, Combination; Endocarditis, Bacterial; Female; Humans; Imipenem; Microbial Sensitivity Tests; Pseudomonas aeruginosa; Pseudomonas Infections; Rabbits; Tobramycin | 2004 |
Case report: Pseudomonas aeruginosa-related intervertebral discitis in a young boy with medulloblastoma.
Topics: Adolescent; Anti-Bacterial Agents; Antineoplastic Agents; Back Pain; Biopsy, Fine-Needle; Bone Neoplasms; Cefepime; Cephalosporins; Cerebellar Neoplasms; Cerebral Ventricle Neoplasms; Diagnosis, Differential; Discitis; Drug Therapy, Combination; Humans; Imipenem; Lumbar Vertebrae; Magnetic Resonance Imaging; Male; Medulloblastoma; Pseudomonas Infections; Thoracic Vertebrae; Treatment Outcome | 2004 |
Simultaneous determination of cefepime and grepafloxacin in human urine by high-performance liquid chromatography.
Topics: Amines; Anti-Bacterial Agents; Buffers; Calibration; Cefepime; Cephalosporins; Chromatography, High Pressure Liquid; Fluoroquinolones; Humans; Hydrogen-Ion Concentration; Piperazines; Reference Standards; Reproducibility of Results; Sensitivity and Specificity | 2004 |
[Cefepime-associated encephalopathy in a patient with septic shock and renal failure].
Topics: Acute Kidney Injury; Adult; Anti-Bacterial Agents; Brain Diseases, Metabolic; Cefepime; Cephalosporins; Female; Humans; Shock, Septic; Treatment Outcome | 2004 |
AmpC beta-lactamase in an Escherichia coli clinical isolate confers resistance to expanded-spectrum cephalosporins.
Topics: Aged; Aged, 80 and over; Amino Acid Sequence; Amino Acid Substitution; Bacterial Proteins; beta-Lactamases; Cefepime; Ceftazidime; Cephalosporin Resistance; Cephalosporins; Cloning, Molecular; DNA, Bacterial; Escherichia coli; Escherichia coli Infections; Female; Humans; Kinetics; Molecular Sequence Data | 2004 |
Cefepime and the inoculum effect in tests with Klebsiella pneumoniae producing plasmid-mediated AmpC-type beta-lactamase.
Topics: Anti-Bacterial Agents; Bacterial Proteins; beta-Lactam Resistance; beta-Lactamases; beta-Lactams; Cefepime; Cephalosporins; Colony Count, Microbial; Humans; Klebsiella pneumoniae; Microbial Sensitivity Tests; Plasmids | 2004 |
Stability of cefepime in icodextrin peritoneal dialysis solution.
Topics: Anti-Bacterial Agents; Cefepime; Cephalosporins; Dialysis Solutions; Drug Incompatibility; Drug Stability; Drug Storage; Glucans; Glucose; Icodextrin; Peritoneal Dialysis; Refrigeration; Time Factors | 2004 |
[Endocarditis due to the Neisseria elongata subspecies nitroreducens].
Topics: Aged; Amikacin; Aorta; Aortic Aneurysm; Aortic Valve; Bacteremia; Cefepime; Cephalosporins; Drug Therapy, Combination; Endocarditis, Bacterial; Humans; Male; Neisseria elongata; Neisseriaceae Infections; Species Specificity; Ultrasonography | 2004 |
Relationship between pharmacokinetics and pharmacodynamics of beta-lactams and outcome.
Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Bacterial Infections; beta-Lactams; Cefepime; Ceftriaxone; Cephalosporins; Female; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; Male; Microbial Sensitivity Tests; Middle Aged; Piperacillin; Treatment Outcome | 2004 |
In vitro activity of cefepime and cefpirome compared to other third-generation cephem antibiotics against gram-negative nosocomial pathogens.
Topics: Cefepime; Cefpirome; Cephalosporins; Cross Infection; Drug Resistance, Bacterial; Gram-Negative Bacteria; Gram-Negative Bacterial Infections; Microbial Sensitivity Tests | 2004 |
Left atrial myxoma prolapsing into the left ventricle. Case report and review of the literature.
Topics: Anti-Bacterial Agents; Cefepime; Ceftazidime; Cephalosporins; Cloxacillin; Combined Modality Therapy; Diagnosis, Differential; Echocardiography, Transesophageal; Gentamicins; Heart Atria; Heart Neoplasms; Heart Ventricles; Humans; Male; Middle Aged; Myxoma; Netilmicin; Streptococcal Infections; Teicoplanin; Treatment Outcome; Vancomycin; Viridans Streptococci | 2004 |
Pharmacodynamics of cefepime alone and in combination with various antimicrobials against methicillin-resistant Staphylococcus aureus in an in vitro pharmacodynamic infection model.
Topics: Anti-Bacterial Agents; Cefepime; Cephalosporins; Colony Count, Microbial; Drug Therapy, Combination; Gentamicins; Half-Life; Humans; Methicillin Resistance; Microbial Sensitivity Tests; Models, Biological; Staphylococcus aureus; Tobramycin | 2005 |
Activity of cefepime and carbapenems in experimental pneumonia caused by porin-deficient Klebsiella pneumoniae producing FOX-5 beta-lactamase.
Topics: Animals; Anti-Bacterial Agents; beta-Lactamases; Carbapenems; Cefepime; Cephalosporins; Colony Count, Microbial; Guinea Pigs; Humans; Imipenem; Klebsiella Infections; Klebsiella pneumoniae; Lung; Meropenem; Microbial Sensitivity Tests; Pneumonia, Bacterial; Porins; Thienamycins; Treatment Outcome | 2005 |
The cost-effectiveness of cefepime plus metronidazole versus imipenem/cilastatin in the treatment of complicated intra-abdominal infection.
Topics: Adult; Aged; APACHE; Bacterial Infections; Cefepime; Cephalosporins; Cilastatin; Cost-Benefit Analysis; Drug Therapy, Combination; Female; Follow-Up Studies; Gastrointestinal Diseases; Humans; Imipenem; Male; Metronidazole; Middle Aged; Probability; Retrospective Studies; Treatment Outcome | 2004 |
Comparative activity of oral and parenteral cephalosporins tested against multidrug-resistant Streptococcus pneumoniae: report from the SENTRY Antimicrobial Surveillance Program (1997-2003).
Topics: Administration, Oral; Cefepime; Ceftriaxone; Cephalosporin Resistance; Cephalosporins; Cohort Studies; Drug Resistance, Multiple, Bacterial; Female; Humans; Infusions, Intravenous; International Cooperation; Male; Microbial Sensitivity Tests; Pneumococcal Infections; Sensitivity and Specificity; Streptococcus pneumoniae | 2005 |
[Imipenem and cefepime in empirical therapy of infectious complications after radical surgeries in patients with invasive cancer of the urinary bladder].
Topics: Adult; Aged; Anti-Bacterial Agents; Cefepime; Cephalosporins; Cystectomy; Female; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; Imipenem; Male; Microbial Sensitivity Tests; Middle Aged; Neoplasm Staging; Postoperative Complications; Retrospective Studies; Urinary Bladder Neoplasms; Urinary Tract Infections | 2004 |
Disposition kinetics, bioavailability and renal clearance of cefepime in calves.
Topics: Animals; Anti-Bacterial Agents; Area Under Curve; Biological Availability; Cattle; Cefepime; Cephalosporins; Creatinine; Cross-Over Studies; Female; Half-Life; Injections, Intramuscular; Injections, Intravenous; Tissue Distribution | 2005 |
Occurrence of extended-spectrum beta-lactamases among chromosomal AmpC-producing Enterobacter cloacae, Citrobacter freundii, and Serratia marcescens in Korea and investigation of screening criteria.
Topics: Anti-Bacterial Agents; Bacterial Proteins; beta-Lactam Resistance; beta-Lactamases; Cefepime; Cephalosporins; Chromosomes, Bacterial; Citrobacter freundii; Conjugation, Genetic; Enterobacter cloacae; Humans; Korea; Microbial Sensitivity Tests; Polymerase Chain Reaction; Sensitivity and Specificity; Serratia marcescens | 2005 |
Continuous infusion beta-lactams for intensive care unit pulmonary infections.
Topics: Anti-Bacterial Agents; Aztreonam; beta-Lactams; Cefepime; Ceftazidime; Cephalosporins; Computer Simulation; Drug Combinations; Gram-Negative Bacteria; Gram-Negative Bacterial Infections; Humans; Infusions, Intravenous; Intensive Care Units; Microbial Sensitivity Tests; Monte Carlo Method; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Pneumonia, Bacterial; United States | 2005 |
[Cefepime-induced encephalopathy: clinical and electroencephalographic features in seven patients].
Topics: Aged; Aged, 80 and over; Anti-Bacterial Agents; Cefepime; Cephalosporins; Electroencephalography; Female; Humans; Male; Middle Aged; Neurotoxicity Syndromes | 2005 |
Comprehensive in vitro evaluation of cefepime combined with aztreonam or ampicillin/sulbactam against multi-drug resistant Pseudomonas aeruginosa and Acinetobacter spp.
Topics: Acinetobacter; Ampicillin; Anti-Bacterial Agents; Aztreonam; Cefepime; Cephalosporins; Drug Combinations; Drug Resistance, Multiple, Bacterial; Drug Synergism; Microbial Sensitivity Tests; Pseudomonas aeruginosa; Sulbactam | 2005 |
Selection of cross-resistance following exposure of Pseudomonas aeruginosa clinical isolates to ciprofloxacin or cefepime.
Topics: Anti-Infective Agents; Cefepime; Cephalosporin Resistance; Cephalosporins; Ciprofloxacin; Humans; Microbial Sensitivity Tests; Pseudomonas aeruginosa; Selection, Genetic | 2005 |
Intermittent administration of betalactam-antibiotics for treatment of severe infection in hemodialysis patients.
Topics: Amoxicillin; Anti-Bacterial Agents; beta-Lactams; C-Reactive Protein; Cefepime; Ceftazidime; Cephalosporins; Female; Gram-Negative Bacterial Infections; Gram-Positive Bacterial Infections; Humans; Male; Middle Aged; Piperacillin; Renal Dialysis; Treatment Outcome | 2005 |
Reevaluation of the cefepime minimal inhibitory concentrations and disk diffusion test zone diameter relationship for a worldwide collection of Enterobacteriaceae enriched for extended-spectrum beta-lactamase-producing organisms.
Topics: Anti-Bacterial Agents; beta-Lactamases; Cefepime; Cephalosporins; Enterobacteriaceae; Enterobacteriaceae Infections; Humans; Immunodiffusion; Microbial Sensitivity Tests; Regression Analysis | 2005 |
Comparative study of the disposition of levofloxacin, netilmicin and cefepime in the isolated rat lung.
Topics: Animals; Anti-Bacterial Agents; Cefepime; Cephalosporins; Kinetics; Levofloxacin; Lung; Male; Netilmicin; Ofloxacin; Organ Culture Techniques; Rats; Rats, Wistar; Respiration, Artificial; Tissue Distribution | 2005 |
Cefepime and continuous renal replacement therapy (CRRT): in vitro permeability of two CRRT membranes and pharmacokinetics in four critically ill patients.
Topics: Acrylic Resins; Acrylonitrile; Adolescent; Aged; Anti-Bacterial Agents; Area Under Curve; Cefepime; Cephalosporins; Chromatography, High Pressure Liquid; Critical Illness; Hemofiltration; Humans; Intensive Care Units; Male; Membranes, Artificial; Metabolic Clearance Rate; Middle Aged; Permeability; Polymers; Sulfones | 2005 |
Population pharmacokinetics of cefepime in the neonate.
Topics: Anti-Bacterial Agents; Cefepime; Cephalosporins; Creatinine; Female; Gestational Age; Humans; Infant; Infant, Newborn; Infant, Premature; Infusions, Intravenous; Intensive Care Units, Neonatal; Male; Software | 2005 |
Trimethoprim-sulfamethoxazole induced rash and fatal hematologic disorders.
Topics: Adult; Anti-Infective Agents; Anti-Inflammatory Agents; Candidiasis, Oral; Cefepime; Cephalosporins; Chlorhexidine; Drug Eruptions; Escherichia coli; Escherichia coli Infections; Exanthema; Fatal Outcome; Filgrastim; Granulocyte Colony-Stimulating Factor; Humans; Male; Meropenem; Neutropenia; Nystatin; Platelet Transfusion; Prednisolone; Recombinant Proteins; Thienamycins; Thrombocytopenia; Trimethoprim, Sulfamethoxazole Drug Combination | 2006 |
Pan-drug-resistant Pseudomonas aeruginosa causing nosocomial infection at a university hospital in Taiwan.
Topics: Adolescent; Adult; Aged; Amikacin; Anti-Bacterial Agents; Cefepime; Cephalosporins; Child; Cross Infection; Drug Resistance, Multiple, Bacterial; Drug Synergism; Female; Hospitals, University; Humans; Male; Microbial Sensitivity Tests; Middle Aged; Pseudomonas aeruginosa; Pseudomonas Infections; Taiwan | 2005 |
[Rapid identification of the isomeric impurity in raw drug of cefepime dihydrochloride by liquid chromatography-tandem mass spectrometry].
Topics: Cefepime; Cephalosporins; Chromatography, Liquid; Drug Contamination; Isomerism; Quality Control; Spectrometry, Mass, Electrospray Ionization | 2005 |
Determination of ceftazidime and cefepime in plasma and dialysate-ultrafiltrate from patients undergoing continuous veno-venous hemodiafiltration by HPLC.
Topics: Anti-Bacterial Agents; Calibration; Cefepime; Ceftazidime; Cephalosporins; Chromatography, High Pressure Liquid; Hemofiltration; Quality Control; Reference Standards; Reproducibility of Results | 2005 |
Pharmacodynamics of intermittent and continuous infusion piperacillin/tazobactam and cefepime against extended-spectrum beta-lactamase-producing organisms.
Topics: beta-Lactam Resistance; beta-Lactamases; Cefepime; Cephalosporins; Drug Therapy, Combination; Escherichia coli; Infusion Pumps; Klebsiella pneumoniae; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination | 2005 |
Effects of hyperbaric oxygen treatment on liver functions, oxidative status and histology in septic rats.
Topics: Animals; Cefepime; Cephalosporins; Hyperbaric Oxygenation; Liver; Male; Oxidative Stress; Rats; Rats, Wistar; Sepsis; Thiobarbituric Acid Reactive Substances | 2005 |
Efficacy of cefepime and imipenem in experimental murine pneumonia caused by porin-deficient Klebsiella pneumoniae producing CMY-2 beta-Lactamase.
Topics: Animals; Anti-Bacterial Agents; beta-Lactamases; Cefepime; Cephalosporins; Disease Models, Animal; Female; Humans; Imipenem; Klebsiella Infections; Klebsiella pneumoniae; Mice; Mice, Inbred C57BL; Microbial Sensitivity Tests; Pneumonia, Bacterial; Porins; Treatment Outcome | 2005 |
Potency and spectrum trends for cefepime tested against 65746 clinical bacterial isolates collected in North American medical centers: results from the SENTRY Antimicrobial Surveillance Program (1998-2003).
Topics: Anti-Bacterial Agents; Cefepime; Cephalosporins; Gram-Negative Bacteria; Gram-Negative Bacterial Infections; Gram-Positive Bacteria; Gram-Positive Bacterial Infections; Humans; Microbial Sensitivity Tests; North America | 2005 |
Failure of cefepime therapy in treatment of Klebsiella pneumoniae bacteremia.
Topics: Anti-Bacterial Agents; Bacteremia; Bacterial Proteins; beta-Lactam Resistance; beta-Lactamases; Cefepime; Cephalosporins; Humans; Klebsiella Infections; Klebsiella pneumoniae; Microbial Sensitivity Tests; Treatment Failure | 2005 |
Cephalosporin-induced nonconvulsive status epilepticus: clinical and electroencephalographic features.
Topics: Adult; Aged; Anti-Bacterial Agents; Cefepime; Cephalosporins; Drug Therapy, Combination; Electroencephalography; Female; Humans; Male; Pyoderma; Status Epilepticus | 2005 |
SHV-type extended-spectrum beta-lactamase production is associated with Reduced cefepime susceptibility in Enterobacter cloacae.
Topics: Anti-Bacterial Agents; beta-Lactamases; Cefepime; Cephalosporin Resistance; Cephalosporins; Electrophoresis, Gel, Pulsed-Field; Enterobacter cloacae; Humans; Microbial Sensitivity Tests; Phenotype | 2005 |
Pharmacodynamics of antimicrobials for the empirical treatment of nosocomial pneumonia: a report from the OPTAMA Program.
Topics: Anti-Bacterial Agents; Cefepime; Ceftazidime; Cephalosporins; Ciprofloxacin; Cross Infection; Dose-Response Relationship, Drug; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; Imipenem; Meropenem; Microbial Sensitivity Tests; Monte Carlo Method; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Pneumonia, Bacterial; Thienamycins | 2005 |
Clinical implications of extended spectrum beta-lactamase (ESBL) producing Klebsiella species and Escherichia coli on cefepime effectiveness.
Topics: Adult; Aged; Anti-Bacterial Agents; beta-Lactamases; Case-Control Studies; Cefepime; Cephalosporins; Drug Resistance, Bacterial; Escherichia coli; Escherichia coli Infections; Female; Humans; Klebsiella; Klebsiella Infections; Male; Microbial Sensitivity Tests; Middle Aged; Treatment Outcome | 2005 |
Nonconvulsive status epilepticus due to cefepime in a patient with normal renal function.
Topics: Aged; Anti-Bacterial Agents; Anticonvulsants; Cefepime; Cephalosporins; Electroencephalography; Female; Humans; Lorazepam; Status Epilepticus; Urinary Tract Infections | 2006 |
Pseudomonas aeruginosa infective endocarditis presenting as bacterial meningitis.
Topics: Acyclovir; Ampicillin; Calcification, Physiologic; Cefepime; Cephalosporins; Community-Acquired Infections; Diagnosis, Differential; Echocardiography, Transesophageal; Endocarditis, Bacterial; Female; Gentamicins; Humans; Meningitis, Bacterial; Middle Aged; Pseudomonas aeruginosa; Pseudomonas Infections; Risk Factors; Vancomycin | 2005 |
Simultaneous determination of cefepime and L-arginine by micellar electrokinetic chromatography and applications to commercial injections.
Topics: Arginine; Cefazolin; Cefepime; Cephalosporins; Chromatography, Micellar Electrokinetic Capillary; Hydrogen-Ion Concentration; Reference Standards; Sodium Dodecyl Sulfate; Tromethamine | 2005 |
Pharmacokinetics of cefepime administered by i.v. and i.m. routes to ewes.
Topics: Animals; Anti-Bacterial Agents; Area Under Curve; Cefepime; Cephalosporins; Cross-Over Studies; Female; Infusions, Intravenous; Injections, Intramuscular; Sheep | 2005 |
Cefepime- and cefixime-induced encephalopathy in a patient with normal renal function.
Topics: Aged, 80 and over; Anti-Bacterial Agents; Brain; Cefepime; Cefixime; Cephalosporins; Confusion; Consciousness Disorders; Delirium; Epididymitis; Humans; Kidney; Male; Metabolic Clearance Rate; Neurotoxicity Syndromes; Penicillanic Acid; Piperacillin; Recovery of Function; Secondary Prevention; Systemic Inflammatory Response Syndrome; Tazobactam; Urinary Tract Infections; Withholding Treatment | 2005 |
Effect of cefepime on startle amplitude and prepulse inhibition of startle reflex in rats: manipulation of GABAA receptor function with midazolam.
Topics: Animals; Cefepime; Cephalosporins; Drug Antagonism; GABA Agonists; GABA Antagonists; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; Male; Midazolam; Rats; Rats, Wistar; Reflex, Startle | 2005 |
[Comparison of different phenotypic methods detecting extended spectrum beta-lactamases in Pseudomonas aeruginosa and Acinetobacter baumannii strains].
Topics: Acinetobacter baumannii; Anti-Bacterial Agents; beta-Lactam Resistance; beta-Lactamase Inhibitors; beta-Lactamases; Cefepime; Cefotaxime; Ceftazidime; Cephalosporins; Clavulanic Acid; Enzyme Inhibitors; Humans; Microbial Sensitivity Tests; Phenotype; Pseudomonas aeruginosa; Sensitivity and Specificity | 2005 |
Emergence of cefotaxime resistance in Citrobacter freundii causing necrotizing fasciitis and osteomyelitis.
Topics: Anti-Bacterial Agents; beta-Lactams; Cefepime; Cefotaxime; Cephalosporin Resistance; Cephalosporins; Citrobacter freundii; Enterobacteriaceae Infections; Ertapenem; Fasciitis, Necrotizing; Female; Humans; Middle Aged; Osteomyelitis; Wounds and Injuries | 2006 |
Case of the month. Chronic recurrent multifocal osteomyelitis.
Topics: Adolescent; Biopsy; Cefepime; Cephalosporins; Chronic Disease; Humans; Humerus; Male; Osteomyelitis; Recurrence; Vancomycin | 2005 |
[Efficacy and safety of cefepime in the treatment of bronchopulmonary disease exacerbation in pediatric patients with mucoviscidosis].
Topics: Adolescent; Anti-Bacterial Agents; Bronchial Diseases; Cefepime; Cephalosporins; Child; Cystic Fibrosis; Female; Humans; Lung Diseases; Male; Pseudomonas aeruginosa; Pseudomonas Infections; Sputum; Staphylococcal Infections; Staphylococcus aureus | 2005 |
Trough serum concentrations of beta-lactam antibiotics in cancer patients: inappropriateness of conventional schedules to pharmacokinetic/pharmacodynamic properties of beta-lactams.
Topics: Adult; Aged; Anti-Bacterial Agents; Bacterial Infections; beta-Lactams; Cefepime; Ceftazidime; Cephalosporins; Drug Administration Schedule; Female; Humans; Imipenem; Male; Middle Aged; Neoplasms; Neutropenia; Prospective Studies | 2006 |
Pharmacodynamic profiling of cefepime in plasma and cerebrospinal fluid of hospitalized patients with external ventriculostomies.
Topics: Adult; Aged; Cefepime; Cephalosporins; Female; Humans; Infusions, Intravenous; Injections, Intravenous; Male; Microbial Sensitivity Tests; Middle Aged; Models, Biological; Monte Carlo Method; Time Factors; Ventriculostomy | 2006 |
Horizontal transfer of blaCMY-bearing plasmids among clinical Escherichia coli and Klebsiella pneumoniae isolates and emergence of cefepime-hydrolyzing CMY-19.
Topics: Amino Acid Sequence; beta-Lactam Resistance; beta-Lactamases; Blotting, Southern; Cefepime; Cephalosporins; Electrophoresis, Gel, Pulsed-Field; Escherichia coli; Gene Transfer, Horizontal; Humans; Isoelectric Focusing; Klebsiella pneumoniae; Molecular Sequence Data; Plasmids; Structure-Activity Relationship | 2006 |
Phenotypic and genotypic detection of ESBL mediated cephalosporin resistance in Klebsiella pneumoniae: emergence of high resistance against cefepime, the fourth generation cephalosporin.
Topics: Anti-Bacterial Agents; beta-Lactamases; Cefepime; Cephalosporin Resistance; Cephalosporins; Genotype; Humans; Klebsiella pneumoniae; Microbial Sensitivity Tests; Phenotype; Polymerase Chain Reaction | 2006 |
Detection of a novel variant bla(CTX-M-3) extended spectrum beta-lactamase gene in a community-acquired Escherichia coli isolate.
Topics: Anti-Bacterial Agents; beta-Lactamases; Cefepime; Cefotaxime; Cephalosporin Resistance; Cephalosporins; Child, Preschool; Community-Acquired Infections; Escherichia coli; Escherichia coli Infections; Female; Genetic Variation; Greece; Humans; Microbial Sensitivity Tests; Polymerase Chain Reaction; Urinary Tract Infections | 2006 |
Pharmacokinetics of cefepime in bile and gall bladder tissue after prophylactic administration in patients with extrahepatic biliary diseases.
Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; Antibiotic Prophylaxis; Area Under Curve; Bile; Cefepime; Cephalosporins; Cholecystectomy; Cholecystitis; Cholecystolithiasis; Female; Gallbladder; Gallbladder Diseases; Humans; Male; Middle Aged; Polyps | 2006 |
Application of the ion pair concept to the n-octanol-water partitioning of cefepime and cefpirome.
Topics: 1-Octanol; Anti-Bacterial Agents; Cefepime; Cefpirome; Cephalosporins; Chromatography, High Pressure Liquid; Hydrogen-Ion Concentration; Ions; Models, Chemical; Molecular Structure; Water | 2006 |
Involvement of the MexXY-OprM efflux system in emergence of cefepime resistance in clinical strains of Pseudomonas aeruginosa.
Topics: Anti-Bacterial Agents; Bacterial Outer Membrane Proteins; Bacterial Proteins; Cefepime; Cephalosporins; Drug Resistance, Bacterial; Humans; Membrane Transport Proteins; Microbial Sensitivity Tests; Phenotype; Pseudomonas aeruginosa | 2006 |
[Maxipime in the treatment of neonatal sepsis].
Topics: Anti-Bacterial Agents; Cefepime; Cephalosporins; Humans; Infant, Newborn; Sepsis; Treatment Outcome | 2006 |
Influence of endotoxin induced fever on the pharmacokinetics of intramuscularly administered cefepime in rabbits.
Topics: Animals; Anti-Bacterial Agents; Area Under Curve; Cefepime; Cephalosporins; Endotoxins; Escherichia coli Infections; Fever; Half-Life; Injections, Intramuscular; Male; Rabbits | 2006 |
Antimicrobial activity of cefepime tested against ceftazidime-resistant Gram-negative clinical strains from North American Hospitals: report from the SENTRY Antimicrobial Surveillance Program (1998-2004).
Topics: Anti-Bacterial Agents; Canada; Cefepime; Ceftazidime; Cephalosporins; Communicable Diseases, Emerging; Drug Interactions; Drug Resistance, Bacterial; Gram-Negative Bacteria; Humans; Microbial Sensitivity Tests; Sentinel Surveillance; United States | 2006 |
[The combination effects of antibacterial agents against clinical isolated multiple-drug resistant Pseudomonas aeruginosa].
Topics: Amikacin; Anti-Bacterial Agents; Aztreonam; Cefepime; Cefoperazone; Cephalosporins; Ciprofloxacin; Drug Combinations; Drug Resistance, Multiple, Bacterial; Drug Therapy, Combination; Fluoroquinolones; Humans; Meropenem; Microbial Sensitivity Tests; Oxazines; Penicillanic Acid; Piperacillin; Pseudomonas aeruginosa; Sulbactam; Tazobactam; Thienamycins | 2006 |
Prospective drug utilization evaluation of three broad-spectrum antimicrobials: cefepime, piperacillin-tazobactam and meropenem.
Topics: Anti-Bacterial Agents; Cefepime; Cephalosporins; Drug Utilization Review; Humans; Meropenem; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Thienamycins | 2006 |
In vivo selection of Enterobacter aerogenes with reduced susceptibility to cefepime and carbapenems associated with decreased expression of a 40 kDa outer membrane protein and hyperproduction of AmpC beta-lactamase.
Topics: Anti-Bacterial Agents; Bacterial Outer Membrane Proteins; Bacterial Proteins; Base Sequence; beta-Lactamases; Carbapenems; Cefepime; Cephalosporins; Enterobacter aerogenes; Humans; Microbial Sensitivity Tests; Molecular Sequence Data | 2006 |
Effect of porins and plasmid-mediated AmpC beta-lactamases on the efficacy of beta-lactams in rat pneumonia caused by Klebsiella pneumoniae.
Topics: Animals; Anti-Bacterial Agents; Bacterial Proteins; beta-Lactamases; beta-Lactams; Cefepime; Cephalosporins; Colony Count, Microbial; Imipenem; In Vitro Techniques; Klebsiella Infections; Klebsiella pneumoniae; Male; Meropenem; Microbial Sensitivity Tests; Plasmids; Pneumonia, Bacterial; Porins; Rats; Rats, Wistar; Thienamycins; Treatment Outcome | 2006 |
[Cefepime as an empiric treatment of febrile neutropenia in patients after high dose therapy and autologous stem cell transplantation].
Topics: Adult; Aged; Anti-Bacterial Agents; Antineoplastic Agents; Bacterial Infections; Cefepime; Cephalosporins; Combined Modality Therapy; Female; Fever; Humans; Lymphoma; Male; Middle Aged; Neutropenia; Stem Cell Transplantation | 2006 |
Stability of cefepime and metronidazole prepared for simplified administration as a single product.
Topics: Anti-Bacterial Agents; Cefepime; Cephalosporins; Drug Combinations; Drug Stability; Metronidazole | 2006 |
[In vitro activity of cefepime against ESBL-positive clinical strains of gram-negative rods].
Topics: beta-Lactam Resistance; beta-Lactamases; Cefepime; Cephalosporins; Drug Resistance, Multiple, Bacterial; Gram-Negative Bacteria; Humans; In Vitro Techniques; Microbial Sensitivity Tests | 2005 |
Clinical experiences of the infections caused by extended-spectrum beta-lactamase-producing Serratia marcescens at a medical center in Taiwan.
Topics: Amikacin; beta-Lactamase Inhibitors; beta-Lactamases; Carbapenems; Cefepime; Cephalosporins; Electrophoresis, Gel, Pulsed-Field; Humans; Imipenem; Microbial Sensitivity Tests; Molecular Epidemiology; Molecular Sequence Data; Polymerase Chain Reaction; Serratia Infections; Serratia marcescens; Taiwan | 2006 |
Treatment of cavitary pulmonary zygomycosis with surgical resection and posaconazole.
Topics: Amphotericin B; Antifungal Agents; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Benzamides; Bone Marrow Transplantation; Cefepime; Cephalosporins; Combined Modality Therapy; Cunninghamella; Daunorubicin; Drug Resistance, Multiple, Fungal; Female; Humans; Imatinib Mesylate; Immunocompromised Host; Lung Diseases, Fungal; Middle Aged; Neutropenia; Piperazines; Pneumonectomy; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Pyrimidines; Transplantation Conditioning; Triazoles; Vancomycin; Vincristine; Voriconazole; Zygomycosis | 2006 |
Effect of a selective decontamination of the digestive tract regimen including parenteral cefepime on establishment of intestinal colonization with vancomycin-resistant Enterococcus spp. and Klebsiella pneumoniae in mice.
Topics: Animals; Anti-Bacterial Agents; Cefepime; Cephalosporins; Decontamination; Enterococcus; Gastrointestinal Tract; Infusions, Parenteral; Intestines; Klebsiella pneumoniae; Mice; Microbial Sensitivity Tests; Vancomycin Resistance | 2006 |
Naturally occurring extended-spectrum cephalosporinases in Escherichia coli.
Topics: Anti-Bacterial Agents; Bacterial Proteins; beta-Lactam Resistance; beta-Lactamases; Cefepime; Ceftazidime; Cephalosporinase; Cephalosporins; Escherichia coli; Genetic Variation; Humans; Microbial Sensitivity Tests; Molecular Sequence Data; Mutation; Sequence Analysis, DNA | 2006 |
The effect of different doses of cisplatin on the pharmacokinetic parameters of cefepime in mice.
Topics: Animals; Animals, Laboratory; Anti-Bacterial Agents; Area Under Curve; Cefepime; Cephalosporins; Cisplatin; Drug Interactions; Half-Life; Kidney Diseases; Male; Mice; Models, Animal; Statistics, Nonparametric | 2006 |
Cefepime- and cefixime-induced encephalopathy in a patient with normal renal function.
Topics: Aged, 80 and over; Anti-Bacterial Agents; Brain; Cefepime; Cefixime; Cephalosporins; Epilepsy, Generalized; Humans; Kidney; Male; Neurotoxicity Syndromes | 2006 |
Modified double-disc test for detection of extended-spectrum beta-lactamases in Escherichia coli and Klebsiella pneumoniae.
Topics: Anti-Bacterial Agents; beta-Lactamases; Cefepime; Cephalosporins; Clavulanic Acid; Drug Resistance, Bacterial; Drug Synergism; Escherichia coli; Klebsiella pneumoniae; Microbial Sensitivity Tests | 2006 |
Comparisons of parenteral broad-spectrum cephalosporins tested against bacterial isolates from pediatric patients: report from the SENTRY Antimicrobial Surveillance Program (1998-2004).
Topics: Adolescent; Anti-Bacterial Agents; Cefepime; Ceftriaxone; Cephalosporins; Child; Child, Preschool; Gram-Negative Bacteria; Gram-Negative Bacterial Infections; Gram-Positive Bacteria; Gram-Positive Bacterial Infections; Humans; Infant; Infant, Newborn; Microbial Sensitivity Tests; North America; Sentinel Surveillance | 2007 |
Comparative in vivo efficacy of meropenem, imipenem, and cefepime against Pseudomonas aeruginosa expressing MexA-MexB-OprM efflux pumps.
Topics: Animals; Anti-Bacterial Agents; Bacterial Outer Membrane Proteins; Cefepime; Cephalosporins; Drug Resistance, Multiple, Bacterial; Female; Imipenem; Membrane Transport Proteins; Meropenem; Mice; Microbial Sensitivity Tests; Pseudomonas aeruginosa; Pseudomonas Infections; Specific Pathogen-Free Organisms; Thienamycins; Thigh; Treatment Outcome | 2007 |
Pharmacokinetic-pharmacodynamic rationale for cefepime dosing regimens in intensive care units.
Topics: Acinetobacter baumannii; Acinetobacter Infections; Adult; Aged; Anti-Bacterial Agents; Cefepime; Cephalosporins; Drug Administration Schedule; Escherichia coli; Escherichia coli Infections; Female; Gram-Negative Bacterial Infections; Humans; Intensive Care Units; Klebsiella Infections; Klebsiella pneumoniae; Male; Microbial Sensitivity Tests; Middle Aged; Models, Biological; Pseudomonas aeruginosa; Pseudomonas Infections | 2006 |
Errors committed by nursing technicians and assistants in administering antibiotics.
Topics: Anti-Bacterial Agents; Brazil; Cefepime; Cephalosporins; Chi-Square Distribution; Humans; Medication Errors; Nursing Assistants | 2006 |
Pyogenic liver abscess: Klebsiella as an emerging pathogen.
Topics: Aged; Anti-Bacterial Agents; Cefepime; Cephalosporins; Humans; Klebsiella Infections; Klebsiella pneumoniae; Liver Abscess, Pyogenic; Male; Tomography, X-Ray Computed | 2006 |
Evaluating broad-spectrum antimicrobials.
Topics: Animals; Anti-Bacterial Agents; Cefepime; Cephalosporins; Humans; Meropenem; Microbial Sensitivity Tests; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Thienamycins | 2006 |
Treatment of bone and joint infections caused by Gram-negative bacilli with a cefepime-fluoroquinolone combination.
Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Bone Diseases, Infectious; Cefepime; Cephalosporins; Ciprofloxacin; Drug Therapy, Combination; Female; Gram-Negative Bacterial Infections; Humans; Joint Diseases; Male; Middle Aged; Ofloxacin; Retrospective Studies | 2006 |
Susceptibilities of Propionibacterium acnes ophthalmic isolates to ertapenem, meropenem, and cefepime.
Topics: Animals; Anti-Bacterial Agents; beta-Lactams; Cefepime; Cephalosporins; Ertapenem; Eye; Meropenem; Microbial Sensitivity Tests; Propionibacterium acnes; Rabbits; Thienamycins | 2006 |
In vitro activity of cefepime combined with sulbactam against clinical isolates of carbapenem-resistant Acinetobacter spp.
Topics: Acinetobacter; Acinetobacter baumannii; Anti-Bacterial Agents; beta-Lactam Resistance; Carbapenems; Cefepime; Cephalosporins; Drug Resistance, Bacterial; Drug Synergism; Humans; Microbial Sensitivity Tests; Sulbactam | 2006 |
[Efficacies of ceftazidime and cefepime in rats with experimental pneumonia caused by extended-spectrum beta-lactamase-producing strain of Klebsiella pneumonia].
Topics: Animals; Anti-Bacterial Agents; beta-Lactamases; Cefepime; Ceftazidime; Cephalosporins; Female; Klebsiella Infections; Klebsiella pneumoniae; Pneumonia, Bacterial; Rats; Rats, Sprague-Dawley | 2006 |
Optimising antibiotic dosing regimens based on pharmacodynamic target attainment against Pseudomonas aeruginosa collected in Hungarian hospitals.
Topics: Anti-Bacterial Agents; Cefepime; Ceftazidime; Cephalosporins; Ciprofloxacin; Computer Simulation; Drug Administration Schedule; Drug Resistance, Bacterial; Humans; Hungary; Imipenem; Infusions, Intravenous; Meropenem; Microbial Sensitivity Tests; Models, Biological; Monte Carlo Method; Pseudomonas aeruginosa; Pseudomonas Infections; Thienamycins | 2006 |
Cefepime pharmacodynamics in patients with extended spectrum beta-lactamase (ESBL) and non-ESBL infections.
Topics: Aged; Anti-Bacterial Agents; beta-Lactamases; Case-Control Studies; Cefepime; Cephalosporins; Escherichia coli; Escherichia coli Infections; Female; Humans; Klebsiella; Klebsiella Infections; Male; Microbial Sensitivity Tests; Middle Aged; Monte Carlo Method; Treatment Outcome | 2007 |
Antibiotic-resistance patterns and frequency of extended-spectrum beta-lactamase-producing isolates of Klebsiella pneumoniae in Tehran.
Topics: Anti-Infective Agents; beta-Lactamases; Cefepime; Cephalosporins; Ciprofloxacin; Drug Evaluation, Preclinical; Drug Resistance, Bacterial; Female; Gentamicins; Humans; Imipenem; Iran; Klebsiella pneumoniae; Male; Meropenem; Thienamycins | 2006 |
Use of cefepime for the treatment of infections caused by extended spectrum beta-lactamase-producing Klebsiella pneumoniae and Escherichia coli.
Topics: Anti-Bacterial Agents; beta-Lactamases; Cefepime; Cephalosporins; Escherichia coli; Escherichia coli Infections; Humans; Klebsiella Infections; Klebsiella pneumoniae; Retrospective Studies | 2006 |
Carbapenem-resistant Acinetobacter baumannii: an emerging threat for patients with post-neurosurgical meningitis.
Topics: Acinetobacter baumannii; Adolescent; Adult; Aged; Amikacin; Anti-Bacterial Agents; Carbapenems; Cefepime; Cefoperazone; Cephalosporins; Ciprofloxacin; Drug Resistance, Bacterial; Female; Gram-Negative Bacteria; Gram-Negative Bacterial Infections; Humans; Imipenem; Male; Meningitis, Bacterial; Meropenem; Microbial Sensitivity Tests; Middle Aged; Neurosurgical Procedures; Postoperative Complications; Thienamycins; Turkey | 2007 |
Bactericidal activity of cefepime and ceftriaxone tested against Streptococcus pneumoniae.
Topics: Anti-Bacterial Agents; Cefepime; Ceftriaxone; Cephalosporins; Humans; Microbial Sensitivity Tests; Sentinel Surveillance; Serum Bactericidal Test; Streptococcus pneumoniae | 2007 |
Comparative activities of cefepime and piperacillin/tazobactam tested against a global collection of Escherichia coli and Klebsiella spp. with an ESBL phenotype.
Topics: Anti-Bacterial Agents; beta-Lactamases; Cefepime; Cephalosporins; Drug Resistance, Multiple, Bacterial; Escherichia coli; Humans; Klebsiella; Microbial Sensitivity Tests; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination | 2007 |
Acute-phase response alters the disposition kinetics of cefepime following intravenous administration to rabbits.
Topics: Acute-Phase Reaction; Animals; Anti-Bacterial Agents; Area Under Curve; Cefepime; Cephalosporins; Escherichia coli; Escherichia coli Infections; Fever; Half-Life; Injections, Intravenous; Male; Rabbits | 2007 |
High-risk febrile neutropenia in Auckland 2003-2004: the influence of the microbiology laboratory on patient treatment and the use of pathogen-specific therapy.
Topics: Anti-Bacterial Agents; Bacteremia; Bacteria; Bacterial Infections; Catheterization; Cefepime; Cephalosporins; Drug Resistance; Equipment Contamination; Fever; Gentamicins; Hematologic Diseases; Hematologic Neoplasms; Hospitals, Urban; Humans; Laboratories, Hospital; Medical Audit; Microbial Sensitivity Tests; Neutropenia; New Zealand; Prospective Studies; Risk Assessment; Species Specificity | 2007 |
Acute neurological deficits caused by cefipime: a case report and review of literature.
Topics: Aged; Aged, 80 and over; Anti-Bacterial Agents; Cefepime; Cephalosporins; Female; Humans; Magnetic Resonance Imaging; Stroke; Urinary Tract Infections | 2006 |
Inhibitory effects of ofloxacin and cefepime on enzyme activity of 6-phosphogluconate dehydrogenase from chicken liver.
Topics: Animals; Anti-Bacterial Agents; Cefepime; Cephalosporins; Chickens; Chromatography, Affinity; Dose-Response Relationship, Drug; Kinetics; Liver; Ofloxacin; Phosphogluconate Dehydrogenase | 2007 |
Breakthrough infection of Trichosporon asahii in a patient with chronic lymphocytic leukemia.
Topics: Aged; Anti-Bacterial Agents; Antifungal Agents; Antineoplastic Combined Chemotherapy Protocols; Cefepime; Cephalosporins; Dermatomycoses; Humans; Itraconazole; Leukemia, Lymphocytic, Chronic, B-Cell; Lung Diseases, Interstitial; Male; Trichosporon | 2007 |
Escherichia coli aortic valve endocarditis.
Topics: Aged; Anti-Bacterial Agents; Aortic Valve; Bacteremia; Cefepime; Cephalosporins; Echocardiography, Transesophageal; Endocarditis, Bacterial; Escherichia coli; Escherichia coli Infections; Follow-Up Studies; Humans; Male; Microbial Sensitivity Tests; Time Factors; Treatment Outcome | 2007 |
Molecular epidemiology and characterization of resistance mechanisms to various antimicrobial agents in Acinetobacter baumannii isolated in Mérida, Venezuela.
Topics: Acinetobacter baumannii; Acinetobacter Infections; Adult; Anti-Bacterial Agents; beta-Lactamases; Cefepime; Cephalosporins; Ciprofloxacin; Disease Outbreaks; DNA Primers; Drug Resistance, Multiple, Bacterial; Electrophoresis, Gel, Pulsed-Field; Genes, Bacterial; Gentamicins; Humans; Imipenem; Infant, Newborn; Tetracyclines; Venezuela | 2007 |
Simultaneous determination of cefepime and vancomycin in plasma and cerebrospinal fluid by MEKC with direct sample injection and application for bacterial meningitis.
Topics: Buffers; Cefepime; Cephalosporins; Chromatography, Micellar Electrokinetic Capillary; Humans; Hydrogen-Ion Concentration; Meningitis, Bacterial; Sodium Dodecyl Sulfate; Tromethamine; Vancomycin | 2007 |
Piperacillin/tazobactam-induced seizure rapidly reversed by high flux hemodialysis in a patient on peritoneal dialysis.
Topics: Anti-Bacterial Agents; Brain; Bronchiectasis; Cefazolin; Cefepime; Cephalosporins; Electroencephalography; Epilepsies, Myoclonic; Female; Humans; Magnetic Resonance Imaging; Middle Aged; Molecular Structure; Penicillanic Acid; Penicillin G; Peritoneal Dialysis, Continuous Ambulatory; Piperacillin; Piperacillin, Tazobactam Drug Combination; Renal Dialysis; Tomography, X-Ray Computed | 2007 |
[Cefepime and aztreonam shortages: we've run out of ammo].
Topics: Anti-Bacterial Agents; Aztreonam; Cefepime; Cephalosporins; Health Planning; Spain | 2007 |
Comparison of the probability of target attainment between ceftriaxone and cefepime in the cerebrospinal fluid and serum against Streptococcus pneumoniae.
Topics: Anti-Bacterial Agents; Blood Chemical Analysis; Cefepime; Ceftriaxone; Cephalosporins; Cerebrospinal Fluid; Female; Humans; Male; Meningitis, Pneumococcal; Middle Aged; Monte Carlo Method; Streptococcus pneumoniae | 2007 |
Use of cefepime for the treatment of infections caused by extended spectrum: beta-lactamase-producing Klebsiella pneumoniae and Escherichia coli.
Topics: Anti-Bacterial Agents; beta-Lactamases; Cefepime; Cephalosporins; Drug Resistance, Multiple, Bacterial; Escherichia coli; Escherichia coli Infections; Hospitals, Urban; Humans; India; Intensive Care Units; Klebsiella Infections; Klebsiella pneumoniae; Meropenem; Microbial Sensitivity Tests; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Sepsis; Thienamycins | 2007 |
Pharmacokinetic and pharmacodynamic profiling of cefepime in plasma and peritoneal fluid of abdominal surgery patients.
Topics: Abdomen; Adult; Algorithms; Anti-Bacterial Agents; Ascitic Fluid; Cefepime; Cephalosporins; Female; Humans; Laparotomy; Male; Microbial Sensitivity Tests; Middle Aged; Monte Carlo Method; Postoperative Complications; Surgical Wound Infection | 2007 |
Interactions of ceftobiprole with beta-lactamases from molecular classes A to D.
Topics: Anti-Bacterial Agents; Bacteria; beta-Lactamases; Cefepime; Ceftazidime; Cephalosporins; Hydrolysis; Kinetics; Microbial Sensitivity Tests; Spectrophotometry, Ultraviolet | 2007 |
Cefepime-induced encephalopathy with triphasic waves in three Asian patients.
Topics: Aged; Anti-Bacterial Agents; Asian People; Cefepime; Cephalosporins; Electroencephalography; Female; Humans; Kidney Failure, Chronic; Liver Cirrhosis; Male; Middle Aged; Neurotoxicity Syndromes; Singapore | 2007 |
Cefepime restriction improves gram-negative overall resistance patterns in neonatal intensive care unit.
Topics: Anti-Bacterial Agents; Cefepime; Cephalosporins; Cohort Studies; Drug Resistance, Multiple, Bacterial; Gram-Negative Bacterial Infections; Humans; Infant, Newborn; Infant, Premature; Intensive Care Units, Neonatal; Meropenem; Microbial Sensitivity Tests; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Prospective Studies; Thienamycins; Time Factors | 2007 |
Could geriatric comprehensive assessment predict the outcome of pneumonia in the very old?
Topics: Aged, 80 and over; Anti-Bacterial Agents; Cefepime; Cephalosporins; Female; Geriatric Assessment; Humans; Male; Pneumonia; Predictive Value of Tests; Prognosis; Risk Factors; Treatment Outcome | 2007 |
Blood-brain barrier penetration of cefepime after neurosurgery.
Topics: Anti-Bacterial Agents; Blood-Brain Barrier; Cefepime; Cephalosporins; Humans; Neurosurgical Procedures | 2007 |
Pharmacokinetic disposition and bioavailability of cefepime in buffalo calves.
Topics: Animals; Animals, Newborn; Anti-Bacterial Agents; Area Under Curve; Biological Availability; Cattle; Cefepime; Cephalosporins; Injections, Intramuscular; Male | 2007 |
Failure of current cefepime breakpoints to predict clinical outcomes of bacteremia caused by gram-negative organisms.
Topics: Aged; Anti-Bacterial Agents; Bacteremia; Cefepime; Cephalosporins; Gram-Negative Bacteria; Humans; Microbial Sensitivity Tests; Middle Aged; Multivariate Analysis; Survival Rate; Treatment Outcome | 2007 |
Pharmacokinetics of ceftazidime and cefepime in burn patients: the importance of age and creatinine clearance.
Topics: Adult; Age Factors; Aged; Aged, 80 and over; Anti-Bacterial Agents; Burns; Cefepime; Ceftazidime; Cephalosporins; Chromatography, High Pressure Liquid; Creatinine; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Humans; Male; Microbial Sensitivity Tests; Middle Aged; Respiration, Artificial; Retrospective Studies | 2007 |
Antibiotic use in nursing home-acquired pneumonia.
Topics: Administration, Oral; Aged; Anti-Bacterial Agents; Cefepime; Ceftriaxone; Cephalosporins; Cross Infection; Drug Therapy, Combination; Drug Utilization; Homes for the Aged; Hospital Mortality; Hospitalization; Humans; Injections, Intramuscular; Nursing Homes; Pneumonia, Aspiration; Pneumonia, Bacterial; Survival Rate; Treatment Failure | 2007 |
Impact of antibiotic restriction on broad spectrum antibiotic usage in the ICU of a developing country.
Topics: Anti-Bacterial Agents; Cefepime; Cephalosporins; Developing Countries; Drug Prescriptions; Drug Resistance, Microbial; Drug Utilization Review; Humans; Imipenem; Intensive Care Units; Medical Order Entry Systems; Organizational Policy; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Polymyxin B; Program Development; Vancomycin | 2007 |
Simultaneous determination of cefepime, vancomycin and imipenem in human plasma of burn patients by high-performance liquid chromatography.
Topics: Adolescent; Anti-Bacterial Agents; Burns; Calibration; Cefepime; Cephalosporins; Chromatography, High Pressure Liquid; Drug Monitoring; Female; Humans; Imipenem; Male; Middle Aged; Reference Standards; Reproducibility of Results; Sensitivity and Specificity; Spectrophotometry, Ultraviolet; Vancomycin | 2007 |
Acquisition of rectal colonization by vancomycin-resistant Enterococcus among intensive care unit patients treated with piperacillin-tazobactam versus those receiving cefepime-containing antibiotic regimens.
Topics: Aged; Anti-Bacterial Agents; Cefepime; Cephalosporins; Culture Media; Enterococcus; Female; Gram-Positive Bacterial Infections; Humans; Intensive Care Units; Male; Microbial Sensitivity Tests; Middle Aged; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Rectum; Vancomycin Resistance | 2008 |
[Pseudoperiodic EEG heralding a cefepime-induced encephalopathy].
Topics: Aged; Anti-Bacterial Agents; Brain Diseases; Cefepime; Cephalosporins; Electroencephalography; Female; Hallucinations; Humans; Mental Disorders | 2007 |
[Emergence of beta-lactam-dependent Bacillus cereus associated with prolonged treatment with cefepime in a neutropenic patient].
Topics: Adolescent; Anti-Bacterial Agents; Bacillaceae Infections; Bacillus cereus; Bacteremia; beta-Lactam Resistance; Cefepime; Cephalosporins; Female; Humans; Microbial Sensitivity Tests; Neutropenia; Risk Factors | 2007 |
The neurotoxicity and safety of treatment with cefepime in patients with renal failure.
Topics: Aged; Aged, 80 and over; Anti-Bacterial Agents; Bacterial Infections; Cefepime; Cephalosporins; Dose-Response Relationship, Drug; Electroencephalography; Female; Glomerular Filtration Rate; Humans; Male; Middle Aged; Neurotoxicity Syndromes; Renal Insufficiency; Retrospective Studies; Treatment Outcome | 2008 |
High-level cefepime resistance in Escherichia coli from Singapore producing OXA-1 beta-lactamase.
Topics: Anti-Bacterial Agents; beta-Lactamases; beta-Lactams; Cefepime; Cephalosporin Resistance; Cephalosporins; Ertapenem; Escherichia coli; Kinetics; Microbial Sensitivity Tests; Molecular Sequence Data; Reverse Transcriptase Polymerase Chain Reaction; Singapore | 2008 |
Relationship between antibiotic use and incidence of MexXY-OprM overproducers among clinical isolates of Pseudomonas aeruginosa.
Topics: Aminoglycosides; Anti-Bacterial Agents; Bacterial Outer Membrane Proteins; Bacterial Proteins; Cefepime; Cephalosporins; Culture Media; Drug Resistance, Multiple; Fluoroquinolones; France; Hospitals, University; Humans; Incidence; Membrane Transport Proteins; Microbial Sensitivity Tests; Mutation; Pseudomonas aeruginosa; Pseudomonas Infections | 2008 |
Research and clinical value of antibacterial-application software.
Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Cefepime; Cephalosporins; Enterobacter cloacae; Enterobacteriaceae Infections; Female; Gentamicins; Humans; Imipenem; Isosorbide Dinitrate; Male; Ofloxacin; Software | 2008 |
In vitro activity of cefepime, imipenem, tigecycline, and gentamicin, alone and in combination, against extended-spectrum beta-lactamase-producing Klebsiella pneumoniae and Escherichia coli.
Topics: Anti-Bacterial Agents; beta-Lactam Resistance; beta-Lactamases; Cefepime; Cephalosporins; Drug Therapy, Combination; Escherichia coli; Gentamicins; Imipenem; Klebsiella pneumoniae; Microbial Sensitivity Tests; Minocycline; Tigecycline | 2008 |
Simultaneous determination of five beta-lactam antibiotics (cefepim, ceftazidim, cefuroxim, meropenem and piperacillin) in human plasma by high-performance liquid chromatography with ultraviolet detection.
Topics: Anti-Bacterial Agents; beta-Lactams; Cefepime; Ceftazidime; Cefuroxime; Cephalosporins; Chromatography, High Pressure Liquid; Drug Stability; Humans; Meropenem; Piperacillin; Quality Control; Reproducibility of Results; Sensitivity and Specificity; Thienamycins | 2008 |
Occurrence of ESBL & Amp-C beta-lactamases & susceptibility to newer antimicrobial agents in complicated UTI.
Topics: Anti-Bacterial Agents; Aztreonam; Bacterial Proteins; beta-Lactamases; Cefepime; Cephalosporins; Drug Resistance, Bacterial; Humans; Penicillanic Acid; Piperacillin; Prospective Studies; Tazobactam; Urinary Tract Infections | 2008 |
Gram-negative organisms predominate in Hickman line-related infections in non-neutropenic patients with hematological malignancies.
Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; Antibiotic Prophylaxis; Bacteremia; Catheterization, Central Venous; Catheters, Indwelling; Cefepime; Cephalosporins; Cohort Studies; Female; Gram-Negative Bacteria; Gram-Negative Bacterial Infections; Hematologic Neoplasms; Humans; Incidence; Male; Middle Aged; Neutropenia; Retrospective Studies; Vancomycin; Victoria | 2008 |
Antimicrobial susceptibilities of geographically diverse clinical human isolates of Leptospira.
Topics: Ampicillin; Anti-Bacterial Agents; Azithromycin; Cefepime; Cefotaxime; Ceftriaxone; Cephalosporins; Ciprofloxacin; Egypt; Hawaii; Humans; Leptospira; Leptospirosis; Levofloxacin; Microbial Sensitivity Tests; Nicaragua; Ofloxacin; Tetracycline; Thailand | 2008 |
Population pharmacokinetics of cefepime in neonates with severe nosocomial infections.
Topics: Anti-Bacterial Agents; Cefepime; Cephalosporins; Cross Infection; Female; Gestational Age; Humans; Infant, Newborn; Infusions, Intravenous; Intensive Care Units, Neonatal; Male; Mexico; Models, Biological; Nonlinear Dynamics | 2008 |
Bacterial and fungal pneumonias after lung transplantation.
Topics: Anti-Bacterial Agents; Antiviral Agents; Candidiasis; Cefepime; Cephalosporins; Cytomegalovirus Infections; Humans; Lung Transplantation; Mycoses; Patient Selection; Pneumonia; Pneumonia, Bacterial; Retrospective Studies | 2008 |
[Preparing antibiotics for infusion: not as simple as it appears!].
Topics: Anti-Bacterial Agents; Brazil; Cefepime; Cephalosporins; Child; Clinical Competence; Curriculum; Data Collection; Hospitals, University; Humans; Infusions, Intravenous; Medication Errors; Pediatric Nursing | 2008 |
First molecular characterization of group B streptococci with reduced penicillin susceptibility.
Topics: Amino Acid Sequence; Amino Acid Substitution; Ampicillin; Anti-Bacterial Agents; Bacterial Proteins; Blotting, Western; Cefepime; Cefotaxime; Ceftizoxime; Cephalosporins; Electrophoresis, Gel, Pulsed-Field; Humans; Japan; Microbial Sensitivity Tests; Molecular Sequence Data; Oxacillin; Penicillin Resistance; Penicillin-Binding Proteins; Penicillins; Sequence Analysis, DNA; Sequence Homology, Amino Acid; Streptococcal Infections; Streptococcus agalactiae | 2008 |
Quantitative assessment of combination antimicrobial therapy against multidrug-resistant Acinetobacter baumannii.
Topics: Acinetobacter baumannii; Acinetobacter Infections; Amikacin; Anti-Infective Agents; Cefepime; Cephalosporins; Drug Antagonism; Drug Resistance, Bacterial; Drug Resistance, Multiple, Bacterial; Drug Synergism; Humans; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin | 2008 |
Restoration of susceptibility of intracellular methicillin-resistant Staphylococcus aureus to beta-lactams: comparison of strains, cells, and antibiotics.
Topics: Anti-Bacterial Agents; beta-Lactams; Carbapenems; Cefepime; Cefuroxime; Cell Line; Cells, Cultured; Cephalosporins; Cloxacillin; Humans; Hydrogen-Ion Concentration; Imipenem; Meropenem; Methicillin; Methicillin Resistance; Microbial Sensitivity Tests; Oxacillin; Phagocytosis; Staphylococcus aureus; Thienamycins | 2008 |
Fever, hip pain, and headache in a 12-year-old girl.
Topics: Anti-Bacterial Agents; Cefepime; Cephalosporins; Child; Diagnosis, Differential; Drug Therapy, Combination; Female; Fever; Fusobacterium Infections; Fusobacterium necrophorum; Headache; Hip; Humans; Magnetic Resonance Imaging; Meropenem; Thienamycins; Tomography, X-Ray Computed; Vancomycin | 2008 |
Kinetic characterization of VIM-7, a divergent member of the VIM metallo-beta-lactamase family.
Topics: Acremonium; Bacterial Proteins; beta-Lactamases; Catalysis; Catalytic Domain; Cefepime; Ceftazidime; Cephalosporins; Kinetics; Models, Molecular; Mutation; Penicillinase; Protein Structure, Tertiary; Recombinant Proteins; Structure-Activity Relationship; Substrate Specificity | 2008 |
[Clinical case of the month. Antibiotics and hemodialysis: three cases of neurotoxicity from Maxipime].
Topics: Aged; Anti-Bacterial Agents; Brain Diseases; Cefepime; Cephalosporins; Female; Humans; Male; Middle Aged; Renal Dialysis | 2008 |
Bacterial resistance surveillance in China: a report from Mohnarin 2004-2005.
Topics: Anti-Bacterial Agents; Cefepime; Cephalosporins; China; Drug Resistance, Bacterial; Enterobacteriaceae; Enterococcus; Haemophilus; Microbial Sensitivity Tests; Staphylococcus; Streptococcus | 2008 |
Cefepime overdosage with neurotoxicity recovered by high-volume haemofiltration.
Topics: Adult; Cefepime; Cephalosporins; Drug Overdose; Hemofiltration; Humans; Male; Neurotoxicity Syndromes | 2008 |
Acute administration of cefepime lowers L-carnitine concentrations in early lactation stage rat milk.
Topics: Amino Acid Transport System ASC; Animals; Anti-Bacterial Agents; Carnitine; Carrier Proteins; Cefepime; Cephalosporins; Female; Immunohistochemistry; Lactation; Mammary Glands, Animal; Membrane Proteins; Milk; Neurotransmitter Transport Proteins; Organic Cation Transport Proteins; Pregnancy; Rats; Rats, Sprague-Dawley; RNA, Messenger; Solute Carrier Family 22 Member 5; Solute Carrier Proteins; Symporters | 2008 |
Emergence of a cefepime- and cefpirome-resistant Citrobacter freundii clinical isolate harbouring a novel chromosomally encoded AmpC beta-lactamase, CMY-37.
Topics: Amino Acid Sequence; Anti-Bacterial Agents; Bacterial Proteins; beta-Lactam Resistance; beta-Lactamases; Cefepime; Cefpirome; Cephalosporin Resistance; Cephalosporins; Chromosomes, Bacterial; Citrobacter freundii; Enterobacteriaceae Infections; Humans; Microbial Sensitivity Tests; Molecular Sequence Data; Phylogeny | 2008 |
Peritoneal pharmacokinetics of cefepime in laparotomy patients with inflammatory bowel disease, and dosage considerations for surgical intra-abdominal infections based on pharmacodynamic assessment.
Topics: Abdomen; Adult; Aged; Anti-Bacterial Agents; Ascitic Fluid; Bacteria, Aerobic; Cefepime; Cephalosporins; Female; Humans; Inflammatory Bowel Diseases; Male; Microbial Sensitivity Tests; Monte Carlo Method; Peritonitis | 2008 |
Development of breakpoints of cephems for intraabdominal infections based on pharmacokinetics and pharmacodynamics in the peritoneal fluid of patients.
Topics: Abdomen; Anti-Bacterial Agents; Ascitic Fluid; Cefepime; Cefotiam; Cefozopran; Cephalosporins; Enterobacteriaceae; Enterobacteriaceae Infections; Humans; Laparotomy; Microbial Sensitivity Tests; Monte Carlo Method; Postoperative Complications; Surgical Wound Infection | 2008 |
Cefepime-induced neutropenia in a teenager.
Topics: Accidents, Traffic; Adolescent; Anti-Bacterial Agents; Cefepime; Cephalosporins; Female; Humans; Neutropenia; Serratia Infections; Serratia marcescens; Spinal Fractures; Spinal Fusion; Surgical Wound Infection; Vancomycin | 2008 |
An in vivo-in vitro study of cefepime and cefazolin dialytic clearance during high-flux hemodialysis.
Topics: Adult; Anti-Bacterial Agents; Cefazolin; Cefepime; Cephalosporins; Female; Hemolysis; Humans; Male; Metabolic Clearance Rate; Middle Aged; Prospective Studies | 2008 |
Antimicrobial activity of cefepime and rifampicin in cerebrospinal fluid in vitro.
Topics: Anti-Bacterial Agents; Cefepime; Cephalosporins; Cerebrospinal Fluid; Colony Count, Microbial; Humans; Microbial Sensitivity Tests; Microbial Viability; Rifampin; Staphylococcus aureus; Time Factors | 2008 |
Agranulocytosis following phenytoin-induced hypersensitivity syndrome.
Topics: Agranulocytosis; Anti-Bacterial Agents; Anticonvulsants; Cefepime; Cephalosporins; Chemical and Drug Induced Liver Injury; Child, Preschool; Disease Progression; Drug Hypersensitivity; Epilepsy; Exanthema; Granulocyte Colony-Stimulating Factor; Humans; Immunoglobulins, Intravenous; Immunosuppressive Agents; Lymphatic Diseases; Male; Phenytoin; Risk Factors; Steroids; Treatment Outcome | 2009 |
Fixed dose combination of cefepime plus amikacin prevent oxidative stress in liver of Mus musculus mice.
Topics: Amikacin; Animals; Anti-Bacterial Agents; Antioxidants; Catalase; Cefepime; Cephalosporins; Drug Combinations; Lipid Peroxidation; Liver; Malondialdehyde; Mice; Oxidative Stress; Superoxide Dismutase | 2008 |
Efficacy and safety of cefepime.
Topics: Anti-Bacterial Agents; Cefepime; Cephalosporins; Clinical Trials as Topic; Gram-Negative Bacterial Infections; Gram-Positive Bacterial Infections; Humans | 2009 |
Failure of cefepime therapy in neutropenic patients with extended-spectrum beta-lactamase-producing Gram-negative bacteraemia.
Topics: Adult; Aged; Anti-Bacterial Agents; Bacteremia; beta-Lactamases; Cefepime; Cephalosporins; Female; Gram-Negative Bacteria; Gram-Negative Bacterial Infections; Humans; Male; Middle Aged; Neutropenia; Treatment Failure; Young Adult | 2009 |
Cefepime MIC breakpoint resettlement in gram-negative bacteria.
Topics: Cefepime; Cephalosporins; Gram-Negative Bacteria; Microbial Sensitivity Tests | 2009 |
Occurrence of efflux mechanism and cephalosporinase variant in a population of Enterobacter aerogenes and Klebsiella pneumoniae isolates producing extended-spectrum beta-lactamases.
Topics: Bacterial Proteins; beta-Lactamases; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Cefepime; Cephalosporinase; Cephalosporins; Drug Resistance, Bacterial; Enterobacter aerogenes; Humans; Klebsiella pneumoniae; Microbial Sensitivity Tests | 2009 |
Azithromycin in Pseudomonas aeruginosa biofilms: bactericidal activity and selection of nfxB mutants.
Topics: Anti-Bacterial Agents; Azithromycin; Bacterial Proteins; Biofilms; Cefepime; Cephalosporins; Ciprofloxacin; Cystic Fibrosis; DNA-Binding Proteins; Humans; Membrane Proteins; Membrane Transport Proteins; Microbial Sensitivity Tests; Mutation; MutS DNA Mismatch-Binding Protein; Pseudomonas aeruginosa; Transcription Factors | 2009 |
Characterization of the charge variants of L2 beta-lactamase in Stenotrophomonas maltophilia.
Topics: Anti-Bacterial Agents; Bacterial Proteins; Base Sequence; beta-Lactamases; Cefepime; Cephalosporins; Conjugation, Genetic; DNA, Bacterial; Electrophoresis, Polyacrylamide Gel; Environmental Microbiology; Genetic Variation; Hydrogen-Ion Concentration; Isoelectric Focusing; Molecular Sequence Data; Polymerase Chain Reaction; Sequence Analysis, DNA; Stenotrophomonas maltophilia | 2009 |
Dose related effect of systemic antibiotics in prevention of postoperative intra-abdominal adhesion formation in experimental animals.
Topics: Animals; Anti-Bacterial Agents; Cefepime; Cephalosporins; Cricetinae; Disease Models, Animal; Injections, Intramuscular; Laparotomy; Mesocricetus; Metronidazole; Postoperative Complications; Random Allocation; Time Factors; Tissue Adhesions; Treatment Outcome | 2008 |
Determination of total cefozopran concentrations in human peritoneal fluid by HPLC with cefepime as an internal standard: Comparative pharmacokinetics in the fluid and plasma.
Topics: Anti-Bacterial Agents; Ascitic Fluid; Cefepime; Cefozopran; Cephalosporins; Chromatography, High Pressure Liquid; Humans; Indicators and Reagents; Reference Standards; Reproducibility of Results; Ultrafiltration | 2009 |
Surveillance of intrahospital infections at the clinic for gynaecology and obstetrics.
Topics: Anti-Bacterial Agents; Bosnia and Herzegovina; Cefepime; Cephalosporins; Cross Infection; Female; Humans; Imipenem; Klebsiella pneumoniae; Obstetrics and Gynecology Department, Hospital; Population Surveillance; Prevalence; Prospective Studies; Proteus mirabilis; Pseudomonas aeruginosa; Staphylococcus aureus; Streptococcus; Surgical Wound Infection; Urinary Tract Infections; Vancomycin | 2009 |
Why the confusion?
Topics: Aged; Anti-Bacterial Agents; Cefepime; Cephalosporins; Confusion; Delirium; Female; Geriatric Assessment; Humans; Psychotropic Drugs; Surgical Wound Infection | 2009 |
Influence of plasma exchange on the disposition of the fourth generation cephalosporin cefepime.
Topics: Adult; Aged; Anti-Infective Agents; Cefepime; Cephalosporins; Chromatography, High Pressure Liquid; Creatinine; Female; Humans; Injections, Intravenous; Male; Middle Aged; Neoplasms; Plasma Exchange; Plasmapheresis | 2009 |
Comparison of different methods of determining beta-lactam susceptibility in clinical strains of Pseudomonas aeruginosa.
Topics: Anti-Bacterial Agents; Automation; Aztreonam; beta-Lactams; Cefepime; Ceftazidime; Cephalosporins; Genetic Predisposition to Disease; Humans; Imipenem; Microbial Sensitivity Tests; Piperacillin; Pseudomonas aeruginosa; Pseudomonas Infections | 2009 |
[Cefepime-induced encephalopathy in patients with renal failure].
Topics: Aged; Anti-Bacterial Agents; Brain Diseases; Cefepime; Cephalosporins; Consciousness Disorders; Female; Humans; Kidney Failure, Chronic; Male; Middle Aged; Myoclonus; Renal Dialysis; Status Epilepticus | 2009 |
In vitro activity of ceftobiprole against Acinetobacter baumannii clinical isolates.
Topics: Acinetobacter baumannii; Acinetobacter Infections; Anti-Bacterial Agents; Cefepime; Ceftazidime; Cephalosporins; Gene Expression; Genes, Bacterial; Humans; Intensive Care Units; Microbial Sensitivity Tests; Pneumonia, Ventilator-Associated | 2009 |
Reduced susceptibility to cefepime among Escherichia coli clinical isolates producing novel variants of CMY-2 beta-lactamase.
Topics: Amino Acid Sequence; Anti-Bacterial Agents; beta-Lactamases; Cefepime; Cephalosporins; Escherichia coli; Microbial Sensitivity Tests; Molecular Sequence Data; Sequence Homology, Amino Acid | 2009 |
A recent evaluation of empirical cephalosporin treatment and antibiotic resistance of changing bacterial profiles in spontaneous bacterial peritonitis.
Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Ascitic Fluid; Bacterial Infections; Cefepime; Cefotaxime; Cephalosporins; Drug Resistance, Bacterial; Enterococcus; Escherichia coli Infections; Female; Humans; Infusions, Intravenous; Klebsiella Infections; Klebsiella pneumoniae; Leukocyte Count; Levofloxacin; Liver Cirrhosis; Male; Microbial Sensitivity Tests; Middle Aged; Neutrophils; Ofloxacin; Peritonitis; Pneumococcal Infections; Pseudomonas aeruginosa; Pseudomonas Infections; Staphylococcal Infections | 2010 |
Pharmacodynamic-based clinical pathway for empiric antibiotic choice in patients with ventilator-associated pneumonia.
Topics: Adult; Aged; Anti-Bacterial Agents; Cefepime; Cephalosporins; Critical Pathways; Drug Administration Schedule; Drug Therapy, Combination; Female; Hospital Mortality; Humans; Intensive Care Units; Length of Stay; Male; Meropenem; Microbial Sensitivity Tests; Middle Aged; Monte Carlo Method; Observation; Pneumonia, Ventilator-Associated; Prospective Studies; Pseudomonas aeruginosa; Pseudomonas Infections; Thienamycins; Tobramycin; Treatment Outcome; Vancomycin; Young Adult | 2010 |
Effect of MexXY overexpression on ceftobiprole susceptibility in Pseudomonas aeruginosa.
Topics: Anti-Bacterial Agents; Bacterial Proteins; Cefepime; Cephalosporins; Drug Resistance, Bacterial; Electrophoresis, Gel, Pulsed-Field; Gene Expression; Microbial Sensitivity Tests; Pseudomonas aeruginosa; Reverse Transcriptase Polymerase Chain Reaction | 2009 |
[Backache with fever and shivering. Dangerous epidural abscess].
Topics: Anti-Bacterial Agents; Back Pain; Cefepime; Cephalosporins; Diagnosis, Differential; Drainage; Epidural Abscess; Fever; Humans; Male; Meropenem; Middle Aged; Myelography; Paresis; Prognosis; Radiography, Abdominal; Shivering; Staphylococcal Infections; Staphylococcus aureus; Thienamycins; Time Factors; Tomography, X-Ray Computed | 2009 |
Nosocomial outbreak of a non-cefepime-susceptible ceftazidime-susceptible Pseudomonas aeruginosa strain overexpressing MexXY-OprM and producing an integron-borne PSE-1 betta-lactamase.
Topics: Adult; Aged; Aged, 80 and over; Animals; Anti-Bacterial Agents; Bacterial Outer Membrane Proteins; Bacterial Proteins; Cefepime; Ceftazidime; Cephalosporins; Cross Infection; Disease Outbreaks; Drug Resistance, Multiple, Bacterial; Drug Utilization; Female; Gene Expression; Genes, Bacterial; Hospitals; Humans; Integrons; Intensive Care Units; Male; Membrane Transport Proteins; Middle Aged; Pseudomonas aeruginosa; Pseudomonas Infections; Respiratory System; Spain | 2009 |
[Impact of administration rate parameter in toxicity test].
Topics: Animals; Anti-Bacterial Agents; Cefepime; Cephalosporins; Dose-Response Relationship, Drug; Injections, Intraperitoneal; Injections, Intravenous; Mice; Pharmaceutical Preparations; Time Factors; Toxicity Tests, Acute | 2009 |
"Aseptic pneumonitis".
Topics: Aged, 80 and over; Anti-Bacterial Agents; Anti-Inflammatory Agents; Betamethasone; Cefepime; Cephalosporins; Humans; Male; Pneumonia; Radiography, Thoracic; Treatment Outcome | 2009 |
Emergence of extended-spectrum beta-lactamase PER-1 in Proteus vulgaris and Providencia stuartii isolates from Algiers, Algeria.
Topics: Algeria; beta-Lactamases; Cefepime; Cefotaxime; Ceftazidime; Cephalosporins; Imipenem; Microbial Sensitivity Tests; Piperacillin; Polymerase Chain Reaction; Proteus vulgaris; Providencia | 2009 |
Evaluation of sensitivity of different organisms to cefepime and tazobactum (megapime XP) in comparison to cefepime and ceftazidime.
Topics: Anti-Bacterial Agents; Bacteria; Cefepime; Ceftazidime; Cephalosporins; Drug Combinations; Gram-Negative Bacteria; Gram-Positive Bacteria; Penicillanic Acid; Tazobactam | 2008 |
Overproduction of K1 enzyme in Klebsiella oxytoca clinical isolates against ceftazidime, cefepime and ceftobiprole.
Topics: Anti-Bacterial Agents; beta-Lactamases; Cefepime; Ceftazidime; Cephalosporins; Humans; Klebsiella oxytoca; Microbial Sensitivity Tests | 2009 |
Evaluation of single-dose pharmacokinetics of cefepime in healthy bull camels (Camelus dromedaries).
Topics: Administration, Intranasal; Animals; Anti-Bacterial Agents; Camelus; Cefepime; Cephalosporins; Chromatography, High Pressure Liquid; Injections, Intravenous; Male | 2009 |
Cefepime and all-cause mortality.
Topics: Anti-Bacterial Agents; Cefepime; Cephalosporins; Humans; Pseudomonas Infections; Randomized Controlled Trials as Topic | 2009 |
New variant of CTX-M-type extended-spectrum beta-lactamases, CTX-M-71, with a Gly238Cys substitution in a Klebsiella pneumoniae isolate from Bulgaria.
Topics: Anti-Bacterial Agents; beta-Lactamases; Bulgaria; Cefepime; Cefotaxime; Ceftazidime; Cephalosporins; Kinetics; Klebsiella pneumoniae; Microbial Sensitivity Tests; Molecular Sequence Data | 2009 |
Cefepime-associated status epilepticus in an ICU patient with renal failure.
Topics: Aged; Anti-Bacterial Agents; Cefepime; Cephalosporins; Female; Humans; Intensive Care Units; Renal Insufficiency; Status Epilepticus | 2009 |
Prolonged bacteraemia caused by VIM-1 metallo-beta-lactamase-producing Proteus mirabilis: first report from Italy.
Topics: Aged; Amikacin; Anti-Bacterial Agents; Bacteremia; beta-Lactamases; Carbapenems; Cefepime; Cephalosporins; Chromosomes, Bacterial; DNA, Bacterial; Humans; Integrons; Italy; Male; Meropenem; Plasmids; Proteus Infections; Proteus mirabilis; Surgical Wound Infection; Thienamycins; Treatment Failure; Treatment Outcome | 2010 |
[Comparative activity of ertapenem against extended-spectrum beta-lactamase-producing or plasmid-mediated AmpC beta-lactamase-producing Klebsiella pneumoniae].
Topics: Amikacin; Anti-Bacterial Agents; Bacterial Outer Membrane Proteins; Bacterial Proteins; beta-Lactam Resistance; beta-Lactamases; beta-Lactams; Cefepime; Cephalosporins; Ertapenem; Imipenem; Klebsiella pneumoniae; Microbial Sensitivity Tests; Porins; R Factors; Substrate Specificity | 2010 |
Assessment of an alternative meropenem dosing strategy compared with imipenem-cilastatin or traditional meropenem dosing after cefepime failure or intolerance in adults with neutropenic fever.
Topics: Adult; Anti-Bacterial Agents; Cefepime; Cephalosporins; Cilastatin; Cilastatin, Imipenem Drug Combination; Cohort Studies; Dose-Response Relationship, Drug; Drug Combinations; Female; Fever; Hospital Mortality; Humans; Imipenem; Male; Meropenem; Middle Aged; Neutropenia; Retreatment; Seizures; Thienamycins; Time Factors | 2009 |
IND-6, a highly divergent IND-type metallo-beta-lactamase from Chryseobacterium indologenes strain 597 isolated in Burkina Faso.
Topics: Adult; Amino Acid Sequence; Anti-Bacterial Agents; beta-Lactamases; Cefepime; Ceftazidime; Cephalexin; Cephalosporins; Cephalothin; Chryseobacterium; Female; Humans; Microbial Sensitivity Tests; Molecular Sequence Data; Phylogeny; Protein Structure, Secondary; Sequence Homology, Amino Acid | 2009 |
Mortality associated with cefepime therapy among neutropenic patients.
Topics: Anti-Bacterial Agents; Cause of Death; Cefepime; Cephalosporins; Humans; Neutropenia; Randomized Controlled Trials as Topic; Risk Factors | 2009 |
Chryseobacterium indologenes bacteremia in an infant.
Topics: Anti-Bacterial Agents; Bacteremia; Cefepime; Cephalosporins; Chryseobacterium; Female; Flavobacteriaceae Infections; Humans; Infant; Microbial Sensitivity Tests; Treatment Outcome | 2010 |
First isolation of a VIM-producing Klebsiella pneumoniae from a seven-year-old child in Venezuela.
Topics: Anti-Bacterial Agents; Aztreonam; beta-Lactam Resistance; beta-Lactamases; Cefepime; Cephalosporins; Child; Cross Infection; Drug Resistance, Multiple, Bacterial; Female; Humans; Imipenem; Klebsiella Infections; Klebsiella pneumoniae; Meropenem; Microbial Sensitivity Tests; Quinolones; Thienamycins; Urine; Venezuela | 2008 |
Detection of the novel extended-spectrum beta-lactamase OXA-161 from a plasmid-located integron in Pseudomonas aeruginosa clinical isolates from Spain.
Topics: Amikacin; Aminoglycosides; Anti-Bacterial Agents; beta-Lactamases; Cefepime; Cephalosporins; Clavulanic Acid; Gentamicins; Humans; Imipenem; Integrons; Meropenem; Molecular Sequence Data; Penicillanic Acid; Piperacillin; Plasmids; Pseudomonas aeruginosa; Pseudomonas Infections; Spain; Tazobactam; Thienamycins | 2009 |
An improved ion chromatographic method for fast and sensitive determination of N-methylpyrrolidine in cefepime hydrochloride.
Topics: Cefepime; Cephalosporins; Chromatography, Liquid; Pyrrolidines; Reproducibility of Results; Sensitivity and Specificity | 2009 |
Cefepime and mortality.
Topics: Amikacin; Anti-Bacterial Agents; Cefepime; Cephalosporins; Drug Resistance, Bacterial; Drug Therapy, Combination; Fever of Unknown Origin; Humans; Neutropenia | 2009 |
Simultaneous multiresponse optimization of an HPLC method to separate seven cephalosporins in plasma and amniotic fluid: application to validation and quantification of cefepime, cefixime and cefoperazone.
Topics: Amniotic Fluid; Calibration; Cefepime; Cefixime; Cefoperazone; Cefotaxime; Ceftazidime; Ceftizoxime; Ceftriaxone; Cephalosporins; Chromatography, High Pressure Liquid; Drug Stability; Female; Humans; Molecular Structure; Pregnancy; Reproducibility of Results; Temperature | 2009 |
Fixed-dose combination of cefepime plus amikacin (potentox) inhibits pneumonia infection.
Topics: Amikacin; Animals; Anti-Bacterial Agents; Antioxidants; Catalase; Cefepime; Cephalosporins; Drug Therapy, Combination; Klebsiella Infections; Klebsiella pneumoniae; Lipid Peroxidation; Male; Malondialdehyde; Oxidative Stress; Pneumonia, Bacterial; Rats; Rats, Wistar; Superoxide Dismutase | 2009 |
Cefepime and mortality in pediatric acute myelogenous leukemia: a retrospective cohort study.
Topics: Adolescent; Animals; Anti-Bacterial Agents; Cefepime; Cephalosporins; Child; Child, Preschool; Cohort Studies; Female; Humans; Immunocompromised Host; Infant; Infant, Newborn; Leukemia, Myeloid, Acute; Male; Opportunistic Infections; Retrospective Studies | 2009 |
A case of severe cefepime-related neutropenia in a 15-year-old patient.
Topics: Adolescent; Anti-Bacterial Agents; Cefepime; Cephalosporins; Humans; Male; Neutropenia; Osteoarthritis; Surgical Wound Infection | 2010 |
Detection of SHV-type extended-spectrum beta-lactamase in Enterobacter isolates.
Topics: Anti-Bacterial Agents; Bacterial Proteins; beta-Lactamases; Cefepime; Cephalosporins; Clavulanic Acid; Enterobacter; Enterobacteriaceae Infections; Humans; Microbial Sensitivity Tests; Sensitivity and Specificity | 2010 |
Post-antibiotic effect of levofloxacin and tobramycin alone or in combination with cefepime against Pseudomonas aeruginosa.
Topics: Anti-Bacterial Agents; Bacteremia; Cefepime; Cephalosporins; Dose-Response Relationship, Drug; Drug Synergism; Drug Therapy, Combination; Humans; Levofloxacin; Microbial Sensitivity Tests; Ofloxacin; Pseudomonas aeruginosa; Time Factors; Tobramycin | 2009 |
Clinical pharmacodynamics of cefepime in patients infected with Pseudomonas aeruginosa.
Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Cefepime; Cephalosporins; Female; Humans; Male; Microbial Sensitivity Tests; Middle Aged; Monte Carlo Method; Pseudomonas aeruginosa; Pseudomonas Infections; Treatment Outcome | 2010 |
Outbreaks of imipenem resistant Acinetobacter baumannii producing OXA-23 beta-lactamase in a tertiary care hospital in Korea.
Topics: Acinetobacter baumannii; Acinetobacter Infections; Anti-Bacterial Agents; beta-Lactamases; beta-Lactams; Cefepime; Cephalosporins; Ciprofloxacin; Disease Outbreaks; Drug Resistance, Multiple, Bacterial; Electrophoresis, Gel, Pulsed-Field; Gentamicins; Humans; Imipenem; Korea; Microbial Sensitivity Tests | 2009 |
Use of the cefepime-clavulanate ESBL Etest for detection of extended-spectrum beta-lactamases in AmpC co-producing bacteria.
Topics: Anti-Bacterial Agents; Bacterial Proteins; beta-Lactamases; Cefepime; Cefotaxime; Ceftazidime; Cephalosporins; Clavulanic Acid; Drug Resistance, Multiple, Bacterial; Enterobacteriaceae; Enterobacteriaceae Infections; Escherichia coli; Humans; Klebsiella pneumoniae; Microbial Sensitivity Tests; Proteus mirabilis; Sensitivity and Specificity | 2009 |
Cefepime and mortality: a real issue?
Topics: Anti-Bacterial Agents; Bacterial Infections; Cefepime; Cephalosporins; Clinical Trials as Topic; Drug Approval; Humans; Meta-Analysis as Topic; United States; United States Food and Drug Administration | 2010 |
Occurrence of ST23 complex phylogroup A Escherichia coli isolates producing extended-spectrum AmpC beta-lactamase in a French hospital.
Topics: Bacterial Proteins; beta-Lactam Resistance; beta-Lactamases; Cefepime; Cefotaxime; Ceftazidime; Cephalosporins; Escherichia coli; Escherichia coli Infections; Escherichia coli Proteins; France; Hospitalization; Humans; Molecular Sequence Data; Mutation; Phylogeny; Promoter Regions, Genetic | 2010 |
Quantitative assessment of combination antimicrobial therapy against multidrug-resistant bacteria in a murine pneumonia model.
Topics: Acinetobacter baumannii; Amikacin; Animals; Anti-Bacterial Agents; Cefepime; Cephalosporins; Disease Models, Animal; Drug Resistance, Multiple, Bacterial; Drug Therapy, Combination; Female; Humans; Lung; Mice; Ofloxacin; Pneumonia, Bacterial; Polymerase Chain Reaction; Pseudomonas aeruginosa; Random Allocation; Survival Analysis | 2010 |
Antistaphylococcal activities of telavancin tested alone and in combination by time-kill assay.
Topics: Aminoglycosides; Anti-Bacterial Agents; Cefepime; Ceftriaxone; Cephalosporins; Ciprofloxacin; Drug Synergism; Gentamicins; Lipoglycopeptides; Meropenem; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Oxacillin; Rifampin; Thienamycins; Time Factors | 2010 |
Empiric combination antibiotic therapy is associated with improved outcome against sepsis due to Gram-negative bacteria: a retrospective analysis.
Topics: Acinetobacter Infections; Adult; Aged; Aminoglycosides; Anti-Bacterial Agents; Carbapenems; Cefepime; Cephalosporins; Cohort Studies; Drug Therapy, Combination; Escherichia coli Infections; Female; Fluoroquinolones; Gram-Negative Bacterial Infections; Hospital Mortality; Humans; Logistic Models; Male; Middle Aged; Multivariate Analysis; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Pseudomonas aeruginosa; Pseudomonas Infections; Retrospective Studies; Sepsis; Shock, Septic | 2010 |
Synergy of fosfomycin with other antibiotics for Gram-positive and Gram-negative bacteria.
Topics: Acinetobacter baumannii; Amikacin; Anti-Bacterial Agents; Bacteria; Cefepime; Ceftazidime; Cephalosporins; Ciprofloxacin; Enterobacteriaceae; Fosfomycin; Gentamicins; Gram-Negative Bacteria; Methicillin Resistance | 2010 |
Optimal cefepime and meropenem dosing for ventilator-associated pneumonia patients with reduced renal function: an update to our clinical pathway.
Topics: Anti-Bacterial Agents; Cefepime; Cephalosporins; Creatinine; Critical Pathways; Drug Administration Schedule; Humans; Meropenem; Pneumonia, Ventilator-Associated; Quality Assurance, Health Care; Renal Insufficiency; Thienamycins | 2010 |
[Change of ESBLs-KPN and ESBLs-ECO after antimicrobial intervention].
Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; beta-Lactamases; Cefepime; Ceftazidime; Cephalosporins; Cross Infection; Escherichia coli; Escherichia coli Infections; Humans; Klebsiella Infections; Klebsiella pneumoniae; Middle Aged | 2010 |
Efficacy of cefepime therapy for Enterobacter bacteraemia, with special emphasis on febrile neutropenic patients.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Bacteremia; Cefepime; Cephalosporins; Enterobacter; Enterobacteriaceae Infections; Female; Fever; Humans; Male; Microbial Sensitivity Tests; Middle Aged; Neutropenia; Treatment Outcome | 2010 |
Cefepime: an underrecognized cause of nonconvulsive status epilepticus.
Topics: Aged; Anti-Bacterial Agents; Benzodiazepines; Cefepime; Cephalosporins; Female; Humans; Kidney Failure, Chronic; Pseudomonas aeruginosa; Pseudomonas Infections; Status Epilepticus | 2010 |
Prospective monitoring of cefepime in intensive care unit adult patients.
Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Cefepime; Cephalosporins; Cross Infection; Europe; Female; Humans; Intensive Care Units; Male; Middle Aged; Monitoring, Physiologic; Pneumonia; Prospective Studies; Young Adult | 2010 |
The novel sensitive and high throughput determination of cefepime in mouse plasma by SCX-LC/MS/MS method following off-line microElution 96-well solid-phase extraction to support systemic antibiotic programs.
Topics: Animals; Cefepime; Cephalosporins; Chromatography, Gel; Female; Linear Models; Mice; Reproducibility of Results; Sensitivity and Specificity; Solid Phase Extraction; Tandem Mass Spectrometry | 2010 |
Excess mortality related to cefepime.
Topics: Anti-Bacterial Agents; Bacterial Infections; Cefepime; Cephalosporins; Humans; Mortality; Product Surveillance, Postmarketing; United States; United States Food and Drug Administration | 2010 |
Maternal and fetal blood levels of moxifloxacin, levofloxacin, cefepime and cefoperazone.
Topics: Adult; Anti-Bacterial Agents; Aza Compounds; Cefepime; Cefoperazone; Cephalosporins; Female; Fetal Blood; Fluoroquinolones; Humans; Infant, Newborn; Injections, Intravenous; Levofloxacin; Maternal-Fetal Exchange; Moxifloxacin; Ofloxacin; Pregnancy; Pregnancy Complications, Infectious; Quinolines | 2010 |
Lactation stage influences drug milk-to-serum values and neonatal exposure risk.
Topics: Animals; Animals, Newborn; Anti-Bacterial Agents; Biological Availability; Cefepime; Cephalosporins; Female; Lactation; Milk; Rats; Rats, Sprague-Dawley; Risk Assessment | 2010 |
Cefepime-resistant Gram-negative bacteremia in febrile neutropenic patients with hematological malignancies.
Topics: Anti-Bacterial Agents; Bacteremia; beta-Lactamases; Cefepime; Cephalosporin Resistance; Cephalosporins; Escherichia coli; Escherichia coli Infections; Fever; Genes, Bacterial; Gram-Negative Bacteria; Gram-Negative Bacterial Infections; Hematologic Neoplasms; Humans; Klebsiella Infections; Klebsiella pneumoniae; Neutropenia; Pseudomonas aeruginosa; Pseudomonas Infections | 2010 |
Acinetobacter endocarditis presenting as a large right atrial mass: an atypical presentation.
Topics: Acinetobacter Infections; Adult; Anti-Bacterial Agents; Catheters, Indwelling; Cefepime; Cephalosporins; Diagnosis, Differential; Endocarditis, Bacterial; Female; Heart Atria; Humans; Kidney Failure, Chronic; Ofloxacin; Ultrasonography; Vancomycin | 2010 |
Extended-spectrum cephalosporinase in Acinetobacter baumannii.
Topics: Acinetobacter baumannii; Amino Acid Sequence; Amino Acid Substitution; Anti-Bacterial Agents; Aztreonam; Bacterial Proteins; beta-Lactamases; Cefepime; Ceftazidime; Cephalosporin Resistance; Cephalosporinase; Cephalosporins; Humans; Microbial Sensitivity Tests; Molecular Sequence Data; Monobactams; Mutagenesis, Site-Directed | 2010 |
The molecular characteristics of cefepime-susceptible Escherichia coli and Klebsiella spp. isolates with a positive β-lactamase screening test result but negative confirmation.
Topics: Anti-Bacterial Agents; beta-Lactamases; Cefepime; Cephalosporins; China; DNA, Bacterial; Escherichia coli; Escherichia coli Infections; Hospitals; Humans; Klebsiella Infections; Klebsiella pneumoniae; Microbial Sensitivity Tests; Microscopy, Electron, Transmission; Plasmids; Polymerase Chain Reaction | 2010 |
Biotic and abiotic degradation of four cephalosporin antibiotics in a lake surface water and sediment.
Topics: Aerobiosis; Anti-Bacterial Agents; Biodegradation, Environmental; Cefepime; Ceftriaxone; Cefuroxime; Cephalosporins; Cephradine; Fresh Water; Geologic Sediments; Nitrates; Oxygen; Photolysis; Water Pollutants, Chemical | 2010 |
[Efficacy of cefixime and cefepime vs. other cephalosporins in experimental plague of albino mice due to variants FI+ and FI- of the plague microbe].
Topics: Animals; Anti-Bacterial Agents; Antigens, Bacterial; Bacterial Capsules; Cefepime; Cefixime; Cephalosporins; Dose-Response Relationship, Drug; Mice; Plague; Species Specificity; Yersinia pestis | 2007 |
Insufficient β-lactam concentrations in the early phase of severe sepsis and septic shock.
Topics: Anti-Bacterial Agents; beta-Lactams; Cefepime; Ceftazidime; Cephalosporins; Chromatography, High Pressure Liquid; Drug Therapy, Combination; Female; Humans; Male; Meropenem; Microbial Sensitivity Tests; Middle Aged; Penicillanic Acid; Piperacillin; Prospective Studies; Sepsis; Shock, Septic; Tazobactam; Thienamycins | 2010 |
Differential selection of single-step AmpC or efflux mutants of Pseudomonas aeruginosa by using cefepime, ceftazidime, or ceftobiprole.
Topics: Anti-Bacterial Agents; Bacterial Proteins; beta-Lactamases; Cefepime; Ceftazidime; Cephalosporins; Microbial Sensitivity Tests; Mutation; Pseudomonas aeruginosa | 2010 |
Cefepime and death: reality to the rescue.
Topics: Anti-Bacterial Agents; Bacterial Infections; Cefepime; Cephalosporins; Humans | 2010 |
Role of changes in the L3 loop of the active site in the evolution of enzymatic activity of VIM-type metallo-beta-lactamases.
Topics: Amino Acid Substitution; Ampicillin; Anti-Bacterial Agents; beta-Lactamases; Catalytic Domain; Cefepime; Ceftazidime; Cephalosporins; Chromatography, Affinity; DNA, Bacterial; Escherichia coli; Evolution, Molecular; Humans; Kinetics; Models, Molecular; Mutagenesis, Site-Directed; Mutant Proteins; Protein Structure, Tertiary; Substrate Specificity | 2010 |
High cefepime plasma concentrations and neurological toxicity in febrile neutropenic patients with mild impairment of renal function.
Topics: Adult; Aged; Cefepime; Cephalosporins; Female; Glomerular Filtration Rate; Hallucinations; Humans; Male; Middle Aged; Nervous System; Neutropenia; Retrospective Studies | 2010 |
High-performance liquid chromatographic determination and pharmacokinetic study of cefepime in goat plasma and milk after pre-column derivatization with Hg(I).
Topics: Animals; Buffers; Cefepime; Cephalosporins; Chromatography, High Pressure Liquid; Goats; Mercury; Milk; Molecular Structure; Plasma; Quality Control; Reference Standards; Sensitivity and Specificity | 2010 |
Asymptomatic catheter related Rhizobium radiobacter infection in a haploidentical hemapoetic stem cell recipient.
Topics: Agrobacterium tumefaciens; Amikacin; Anti-Bacterial Agents; Blood; Catheter-Related Infections; Catheterization, Central Venous; Catheters; Cefepime; Cephalosporins; Cross Infection; Female; Gram-Negative Bacterial Infections; Humans; Immunocompromised Host; Infant; Severe Combined Immunodeficiency; Stem Cell Transplantation | 2010 |
[Multiple brain abscesses complicating Enterobacter cloacae sepsis in a premature infant].
Topics: Amikacin; Anti-Bacterial Agents; Cefepime; Cephalosporins; Ciprofloxacin; Enterobacter cloacae; Enterobacteriaceae Infections; Humans; Infant; Infant, Newborn; Infant, Premature; Treatment Outcome | 2010 |
Outpatient treatment with intravenous antimicrobial therapy and oral levofloxacin in patients with febrile neutropenia and hematological malignancies.
Topics: Adult; Anti-Bacterial Agents; Cefepime; Cephalosporins; Fever; Hematologic Neoplasms; Home Infusion Therapy; Humans; Injections, Intravenous; Levofloxacin; Male; Middle Aged; Neutropenia; Ofloxacin; Retrospective Studies; Teicoplanin; Treatment Outcome | 2011 |
Emergence of fluoroquinolone-resistant Streptococcus pneumoniae in Lebanon: a report of three cases.
Topics: Aged; Anti-Bacterial Agents; Cefepime; Ceftazidime; Cephalosporins; Clarithromycin; Drug Resistance, Multiple, Bacterial; Humans; Imipenem; Lebanon; Levofloxacin; Male; Ofloxacin; Pneumococcal Infections; Pneumonia, Pneumococcal; Streptococcus pneumoniae; Vancomycin | 2010 |
Novel daptomycin combinations against daptomycin-nonsusceptible methicillin-resistant Staphylococcus aureus in an in vitro model of simulated endocardial vegetations.
Topics: Acetamides; Anti-Infective Agents; Cefepime; Cephalosporins; Daptomycin; Drug Combinations; Endocarditis, Bacterial; Linezolid; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Nafcillin; Oxazolidinones; Trimethoprim, Sulfamethoxazole Drug Combination | 2010 |
The importance of pharmacokinetic consultation of cefepime treatment for Pseudomonas aeruginosa bacteremia: a case report of severe thermal burn injury.
Topics: Anti-Bacterial Agents; Bacteremia; Burns; Cefepime; Cephalosporins; Humans; Male; Middle Aged; Pseudomonas aeruginosa; Pseudomonas Infections | 2011 |
A simple and rapid dispersive liquid-liquid microextraction method followed by GC-FID for determination of N-methylpyrrolidine in cefepime.
Topics: Anti-Bacterial Agents; Buffers; Cefepime; Cephalosporins; Chromatography, Gas; Hydrogen-Ion Concentration; Limit of Detection; Osmolar Concentration; Pyrrolidines; Reference Standards; Reproducibility of Results; Solvents | 2010 |
Identification and characterization of new degradation products of cefepime dihydrochloride monohydrate drug substance during stress stability studies.
Topics: Anti-Bacterial Agents; Cefepime; Cephalosporins; Drug Contamination; Drug Stability; Furans; Hot Temperature; Molecular Structure; Oxidation-Reduction; Photolysis; Thiazines | 2010 |
Validation of capillary electrophoresis method for determination of N-methylpyrrolidine in cefepime for injection.
Topics: Cefepime; Cephalosporins; Drug Contamination; Electrophoresis, Capillary; Pyrrolidines | 2010 |
Steady-state pharmacokinetics and pharmacodynamics of cefepime administered by prolonged infusion in hospitalised patients.
Topics: Adult; Aged; Anti-Bacterial Agents; Cefepime; Cephalosporins; Female; Gram-Negative Bacterial Infections; Hospitals; Humans; Infusions, Intravenous; Male; Microbial Sensitivity Tests; Middle Aged; Models, Statistical; Monte Carlo Method; Plasma; Time Factors | 2011 |
Molecular analysis of antimicrobial agent translocation through the membrane porin BpsOmp38 from an ultraresistant Burkholderia pseudomallei strain.
Topics: Amino Acid Sequence; Anti-Infective Agents; Bacterial Outer Membrane Proteins; beta-Lactams; Biological Transport; Burkholderia pseudomallei; Cefepime; Ceftazidime; Cephalosporins; Ertapenem; Humans; Imipenem; Kinetics; Lipid Bilayers; Melioidosis; Meropenem; Models, Molecular; Molecular Sequence Data; Norfloxacin; Penicillin G; Phospholipids; Porins; Protein Conformation; Sequence Homology, Amino Acid; Thienamycins | 2011 |
Melioidosis presenting as sepsis syndrome: a case report.
Topics: Anti-Bacterial Agents; Bacteremia; Burkholderia pseudomallei; Cefepime; Ceftazidime; Cephalosporins; Ciprofloxacin; Drug Therapy, Combination; Humans; Male; Melioidosis; Microbial Sensitivity Tests; Middle Aged; Trimethoprim, Sulfamethoxazole Drug Combination | 2011 |
Extragenitourinary malakoplakia in a patient with myeloma clinically mimicking extramedullary myelomatous disease.
Topics: Aged; Anti-Bacterial Agents; Cefepime; Cephalosporins; Escherichia coli Infections; Humans; Malacoplakia; Male; Metronidazole; Multiple Myeloma; Neoplasm Metastasis; Soft Tissue Neoplasms; Stem Cell Transplantation | 2011 |
Investigating the impact of the definition of previous antibiotic exposure related to isolation of extended spectrum β-lactamase-producing Klebsiella pneumoniae.
Topics: Aged; Aged, 80 and over; Anti-Bacterial Agents; beta-Lactamases; Black or African American; Case-Control Studies; Cefepime; Cephalosporins; Cohort Studies; Cross Infection; Female; Fluoroquinolones; Humans; Klebsiella Infections; Klebsiella pneumoniae; Male; Michigan; Middle Aged; Multivariate Analysis; Nursing Homes; Odds Ratio; Renal Dialysis; Retrospective Studies; Risk Factors; United States | 2011 |
Activity of ACHN-490 tested alone and in combination with other agents against Pseudomonas aeruginosa.
Topics: Anti-Bacterial Agents; Carbapenems; Cefepime; Cephalosporins; Doripenem; Imipenem; Microbial Sensitivity Tests; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Pseudomonas aeruginosa | 2011 |
Klebsiella pneumoniae outer membrane porins OmpK35 and OmpK36 play roles in both antimicrobial resistance and virulence.
Topics: Animals; Bacterial Proteins; Cefepime; Cefoxitin; Ceftazidime; Cephalosporins; Drug Resistance, Multiple, Bacterial; Genetic Complementation Test; Klebsiella Infections; Klebsiella pneumoniae; Male; Meropenem; Mice; Mice, Inbred BALB C; Microbial Sensitivity Tests; Molecular Sequence Data; Phagocytosis; Porins; Sequence Analysis, DNA; Thienamycins; Virulence | 2011 |
Systemic lupus erythematosus induced by cefepime.
Topics: Adolescent; Anti-Bacterial Agents; Cefepime; Cephalosporins; Humans; Hypotension; Lupus Erythematosus, Systemic; Male | 2011 |
Antibiotic stability in commercial peritoneal dialysis solutions: influence of formulation, storage and duration.
Topics: Ampicillin; Anti-Bacterial Agents; Bacteria; Cefazolin; Cefepime; Cephalosporins; Chemistry, Pharmaceutical; Dialysis Solutions; Drug Stability; Drug Storage; Humans; Peritoneal Dialysis; Peritonitis | 2011 |
Cefepime-related encephalopathy in peritoneal dialysis patients.
Topics: Aged; Aged, 80 and over; Anti-Bacterial Agents; Brain Diseases; Cefepime; Cephalosporins; Female; Humans; Kidney Failure, Chronic; Peritoneal Dialysis | 2011 |
Overexpression of AmpC and efflux pumps in Pseudomonas aeruginosa isolates from bloodstream infections: prevalence and impact on resistance in a Spanish multicenter study.
Topics: Anti-Bacterial Agents; Bacterial Outer Membrane Proteins; Bacterial Proteins; beta-Lactamases; Carbapenems; Cefepime; Ceftazidime; Cephalosporins; Imipenem; Membrane Transport Proteins; Meropenem; Microbial Sensitivity Tests; Porins; Pseudomonas aeruginosa; Reverse Transcriptase Polymerase Chain Reaction; Thienamycins | 2011 |
AmpG inactivation restores susceptibility of pan-beta-lactam-resistant Pseudomonas aeruginosa clinical strains.
Topics: Aztreonam; Bacterial Proteins; beta-Lactams; Cefepime; Ceftazidime; Cephalosporins; Drug Resistance, Bacterial; Membrane Transport Proteins; Meropenem; Microbial Sensitivity Tests; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Pseudomonas aeruginosa; Thienamycins | 2011 |
Impact of evaluating antibiotic concentrations in abdominal abscesses percutaneously drained.
Topics: Abdominal Abscess; Aged; Aged, 80 and over; Anti-Bacterial Agents; Cefepime; Cephalosporins; Ciprofloxacin; Exudates and Transudates; Female; Fluconazole; Humans; Male; Metronidazole; Middle Aged; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Prospective Studies; Suction; Treatment Outcome; Vancomycin | 2011 |
Stability of cefepime in aqueous eye drops.
Topics: Anti-Bacterial Agents; Cefepime; Cephalosporins; Chromatography, High Pressure Liquid; Drug Stability; Drug Storage; Excipients; Hydrogen-Ion Concentration; Indicators and Reagents; Ophthalmic Solutions; Osmolar Concentration; Reproducibility of Results; Sterilization; Temperature; Viscosity | 2011 |
Cefepime effectiveness in Gram-negative bloodstream infections.
Topics: Aged; Anti-Bacterial Agents; Bacteremia; Cefepime; Cephalosporins; Cohort Studies; Female; Gram-Negative Bacterial Infections; Humans; Male; Middle Aged; Retrospective Studies; Treatment Outcome; United States | 2011 |
Cefepime resistance and associated risk factors among Escherichia coli strains isolated from clinical specimens.
Topics: Case-Control Studies; Catheters; Cefepime; Cephalosporin Resistance; Cephalosporins; Escherichia coli; Escherichia coli Infections; Female; Humans; Iran; Length of Stay; Male; Risk Factors; Ventilators, Mechanical | 2011 |
Antibiotic resistance in Pseudomonas aeruginosa related to quinolone formulary changes: an interrupted time series analysis.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Cefepime; Cephalosporins; Drug Resistance, Multiple, Bacterial; Fluoroquinolones; Formularies, Hospital as Topic; Humans; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Pseudomonas aeruginosa; Pseudomonas Infections; Tobramycin | 2011 |
Septic elbow in the setting of neuropathic joint as the initial presentation of a cervical syrinx.
Topics: Anti-Bacterial Agents; Arthritis, Infectious; Arthropathy, Neurogenic; Cefepime; Cephalosporins; Cervical Vertebrae; Elbow Joint; Humans; Magnetic Resonance Imaging; Male; Methicillin-Resistant Staphylococcus aureus; Middle Aged; Staphylococcal Infections; Syringomyelia; Treatment Refusal; Vancomycin | 2011 |
Is cefepime safe for clinical use? A Bayesian viewpoint.
Topics: Anti-Bacterial Agents; Bacterial Infections; Cefepime; Cephalosporins; Fever of Unknown Origin; Humans; Incidence; Neutropenia; Skin Diseases, Bacterial; Statistics as Topic; United States | 2011 |
Rare case of large double perforated anterior mitral leaflet pseudoaneurysm in a patient with aortic valve endocarditis.
Topics: Aged; Aneurysm, False; Anti-Bacterial Agents; Aortic Valve; Aortic Valve Insufficiency; Aortic Valve Stenosis; Cefepime; Cephalosporins; Drug Therapy, Combination; Echocardiography; Echocardiography, Doppler, Color; Echocardiography, Transesophageal; Endocarditis, Bacterial; Enterococcus; Gram-Positive Bacterial Infections; Heart Failure; Heart Valve Prosthesis Implantation; Humans; Male; Mitral Valve; Mitral Valve Insufficiency; Tricuspid Valve Insufficiency; Vancomycin | 2011 |
Mechanisms of resistance in clinical isolates of Pseudomonas aeruginosa less susceptible to cefepime than to ceftazidime.
Topics: Anti-Bacterial Agents; Bacterial Outer Membrane Proteins; Bacterial Proteins; beta-Lactam Resistance; beta-Lactamases; Cefepime; Ceftazidime; Cephalosporins; Female; Gene Expression Profiling; Humans; Male; Membrane Proteins; Membrane Transport Proteins; Microbial Sensitivity Tests; Mutation, Missense; Pseudomonas aeruginosa; Pseudomonas Infections; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction | 2011 |
Cefepime neurotoxicity despite renal adjusted dosing.
Topics: Aged; Anti-Bacterial Agents; Cefepime; Cephalosporins; Electroencephalography; Female; Humans; Neurotoxicity Syndromes; Status Epilepticus | 2011 |
The impact of a nationwide antibiotic restriction program on antibiotic usage and resistance against nosocomial pathogens in Turkey.
Topics: Acinetobacter; Anti-Bacterial Agents; Cefepime; Ceftazidime; Ceftriaxone; Cephalosporins; Cost Savings; Cross Infection; Drug Costs; Drug Prescriptions; Drug Resistance, Bacterial; Drug Utilization; Escherichia; Health Policy; Hospitals; Humans; Imipenem; Klebsiella; Meropenem; Methicillin Resistance; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Pseudomonas; Staphylococcus aureus; Teicoplanin; Thienamycins; Turkey; Vancomycin | 2011 |
Recommended β-lactam regimens are inadequate in septic patients treated with continuous renal replacement therapy.
Topics: Aged; Anti-Bacterial Agents; beta-Lactams; Cefepime; Ceftazidime; Cephalosporins; Dose-Response Relationship, Drug; Female; Humans; Intensive Care Units; Male; Meropenem; Microbial Sensitivity Tests; Middle Aged; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Practice Guidelines as Topic; Prospective Studies; Pseudomonas aeruginosa; Renal Replacement Therapy; Shock, Septic; Thienamycins | 2011 |
Acute kidney injury from pyelonephritis in an elderly man: case report.
Topics: Acute Kidney Injury; Aged; Anti-Bacterial Agents; Cefepime; Cephalosporins; Diagnosis, Differential; Escherichia coli Infections; Humans; Male; Ofloxacin; Pyelonephritis; Renal Dialysis | 2011 |
False extended-spectrum {beta}-lactamase phenotype in clinical isolates of Escherichia coli associated with increased expression of OXA-1 or TEM-1 penicillinases and loss of porins.
Topics: Anti-Bacterial Agents; Bacterial Outer Membrane Proteins; beta-Lactamases; Cefepime; Cefpirome; Cephalosporins; Clavulanic Acid; DNA; DNA, Recombinant; Drug Resistance, Bacterial; Electrophoresis, Gel, Pulsed-Field; Enzyme Inhibitors; Escherichia coli; Escherichia coli Infections; Isoelectric Focusing; Microbial Sensitivity Tests; Plasmids; Porins; Reverse Transcriptase Polymerase Chain Reaction; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Transformation, Bacterial | 2011 |
Cefepime-resistant Pseudomonas aeruginosa.
Topics: Anti-Bacterial Agents; Case-Control Studies; Cefepime; Cephalosporins; Drug Resistance, Bacterial; Female; Humans; Male; Microbial Sensitivity Tests; Middle Aged; Pseudomonas aeruginosa; Pseudomonas Infections | 2011 |
Extended-spectrum AmpC cephalosporinase in Acinetobacter baumannii: ADC-56 confers resistance to cefepime.
Topics: Acinetobacter baumannii; Anti-Bacterial Agents; Bacterial Proteins; beta-Lactamases; Cefepime; Cephalosporin Resistance; Cephalosporinase; Cephalosporins; Drug Resistance, Bacterial; Genes, Bacterial; Microbial Sensitivity Tests; Molecular Sequence Data | 2011 |
Effect of spacer sequences between bla(CTX-M) and ISEcp1 on bla(CTX-M) expression.
Topics: Anti-Bacterial Agents; beta-Lactamases; Cefepime; Cefotaxime; Cephalosporin Resistance; Cephalosporins; DNA Transposable Elements; DNA, Intergenic; Gene Expression; Klebsiella pneumoniae; Plasmids; Promoter Regions, Genetic; RNA, Bacterial; RNA, Messenger | 2011 |
Antimicrobial resistance and prevalence of virulence factor genes in fecal Escherichia coli of Holstein calves fed milk with and without antimicrobials.
Topics: Animals; Animals, Suckling; Anti-Infective Agents; Cattle; Cefepime; Cephalosporins; Ciprofloxacin; Disk Diffusion Antimicrobial Tests; DNA Gyrase; Drug Resistance, Bacterial; Drug Resistance, Multiple, Bacterial; Escherichia coli; Feces; Milk; Phylogeny; Virulence Factors | 2011 |
Neurotoxicity due to cefepime in patients on maintenance hemodialysis.
Topics: Aged; Anti-Bacterial Agents; Aphasia; Cefepime; Cephalosporins; Comorbidity; Female; Humans; Kidney; Kidney Failure, Chronic; Male; Middle Aged; Myoclonus; Pulmonary Edema; Renal Dialysis; Respiratory Tract Infections | 2011 |
[Actual aspects of sepsis].
Topics: Acetamides; Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Carbapenems; Cefepime; Cephalosporins; Drug Resistance, Microbial; Enterobacteriaceae; Female; Gram-Negative Bacterial Infections; Gram-Positive Bacteria; Gram-Positive Bacterial Infections; Hospitals; Humans; Linezolid; Male; Microbial Sensitivity Tests; Middle Aged; Oxazolidinones; Retrospective Studies; Russia; Sepsis; Vancomycin | 2011 |
[Cefepime versus piperacillin/tazobactam with or without amikacin in the treatment of febrile hematological and oncological neutropenic patients in an internal medicine ward].
Topics: Adult; Aged; Amikacin; Anti-Bacterial Agents; Cefepime; Cephalosporins; Drug Therapy, Combination; Female; Fever; Hematologic Neoplasms; Humans; Male; Middle Aged; Neoplasms; Neutropenia; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Retrospective Studies; Risk Factors; Treatment Outcome | 2010 |
Clinical and electroencephalographic assessment of cefepime during treatment of nosocomial infections in neurological patients.
Topics: Adult; Anti-Bacterial Agents; Cefepime; Cephalosporins; Cross Infection; Electroencephalography; Female; Humans; Infusions, Intravenous; Male; Mental Disorders; Microbial Sensitivity Tests; Middle Aged; Pilot Projects; Young Adult | 2011 |
[Assessment of efficacies of imipenem, cefoperazone-sulbactam and cefepime in rats with experimental thigh abscess model with multidrug resistant and susceptible Acinetobacter baumannii strains].
Topics: Abscess; Acinetobacter baumannii; Acinetobacter Infections; Animals; Anti-Bacterial Agents; Cefepime; Cefoperazone; Cephalosporins; Colony Count, Microbial; Disease Models, Animal; Drug Combinations; Drug Resistance, Multiple, Bacterial; Female; Imipenem; Random Allocation; Rats; Rats, Wistar; Serum Bactericidal Test; Soft Tissue Infections; Sulbactam; Thigh | 2011 |
Effect of a cholesterol rich diet, recurrent infection and possible treatment modalities on the pulmonary vascular system: an experimental study.
Topics: Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Atherosclerosis; Cefepime; Cephalosporins; Cholesterol, Dietary; Diclofenac; Hypercholesterolemia; Pseudomonas Infections; Pulmonary Artery; Rats; Wine | 2011 |
Cefepime-associated thrombocytopenia in a critically ill patient.
Topics: Acute Kidney Injury; Anti-Bacterial Agents; Cefepime; Cephalosporins; Critical Illness; Cross Infection; Humans; Intensive Care Units; Male; Middle Aged; Pneumothorax; Rhabdomyolysis; Sepsis; Thrombocytopenia | 2011 |
Continuous epileptiform discharges in patients treated with cefepime or meropenem.
Topics: Aged; Aged, 80 and over; Anti-Bacterial Agents; Bacterial Infections; Belgium; Cefepime; Cephalosporins; Cross-Over Studies; Electroencephalography; Epilepsy; Female; Humans; Male; Meropenem; Middle Aged; Pharmacy Service, Hospital; Retrospective Studies; Thienamycins | 2011 |
Genetic characterization of an extended-spectrum AmpC cephalosporinase with hydrolysing activity against fourth-generation cephalosporins in a clinical isolate of Enterobacter aerogenes selected in vivo.
Topics: Anti-Bacterial Agents; Cefepime; Cephalosporinase; Cephalosporins; DNA, Bacterial; Enterobacter aerogenes; Enterobacteriaceae Infections; Hydrolysis; Microbial Sensitivity Tests; Molecular Sequence Data; Selection, Genetic; Sequence Analysis, DNA | 2012 |
Resistance emergence mechanism and mechanism of resistance suppression by tobramycin for cefepime for Pseudomonas aeruginosa.
Topics: Anti-Bacterial Agents; Bacterial Proteins; beta-Lactamases; Blotting, Western; Cefepime; Cephalosporins; Computer Simulation; Drug Administration Schedule; Drug Interactions; Drug Resistance, Bacterial; Gene Expression Regulation, Bacterial; Microbial Sensitivity Tests; Models, Biological; Monte Carlo Method; Protein Synthesis Inhibitors; Pseudomonas aeruginosa; Pseudomonas Infections; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tobramycin | 2012 |
Changes in the use of broad-spectrum antibiotics after cefepime shortage: a time series analysis.
Topics: Anti-Bacterial Agents; Cefepime; Cephalosporins; Drug Resistance, Bacterial; Drug Utilization; Health Policy; Hospitals; Humans; Meropenem; Microbial Sensitivity Tests; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Policy; Pseudomonas aeruginosa; Switzerland; Thienamycins; Time Factors | 2012 |
Underdosing of common antibiotics for obese patients in the ED.
Topics: Anti-Bacterial Agents; Bacterial Infections; Body Weight; Cefazolin; Cefepime; Cephalosporins; Ciprofloxacin; Emergency Service, Hospital; Humans; Obesity; Retrospective Studies | 2012 |
Efficacy of doripenem against Escherichia coli and Klebsiella pneumoniae in experimental meningitis.
Topics: Animals; Anti-Bacterial Agents; Bacterial Load; Carbapenems; Cefepime; Cephalosporins; Disease Models, Animal; Doripenem; Escherichia coli; Escherichia coli Infections; Klebsiella Infections; Klebsiella pneumoniae; Meningitis, Bacterial; Rabbits; Treatment Outcome | 2012 |
Cefepime dosing in the morbidly obese patient population.
Topics: Anti-Bacterial Agents; Cefepime; Cephalosporins; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Female; Gram-Negative Bacterial Infections; Gram-Positive Bacterial Infections; Humans; Male; Microbial Sensitivity Tests; Surgical Wound Infection; Treatment Outcome | 2012 |
Low cefepime concentrations during high blood and dialysate flow continuous venovenous hemodialysis.
Topics: Adult; Anti-Bacterial Agents; Cefepime; Cephalosporins; Chromatography, High Pressure Liquid; Female; Half-Life; Hemofiltration; Humans; Kidney Failure, Chronic; Kidney Tubular Necrosis, Acute; Male; Microbial Sensitivity Tests; Middle Aged; Pseudomonas aeruginosa; Shock, Cardiogenic; Spectrophotometry, Ultraviolet; Young Adult | 2012 |
Blood and CSF monitoring of cefepime-induced neurotoxicity: nine case reports.
Topics: Aged; Aged, 80 and over; Anti-Bacterial Agents; Blood Chemical Analysis; Cefepime; Cephalosporins; Cerebrospinal Fluid; Drug Monitoring; Female; Humans; Male; Middle Aged | 2012 |
Cervical osteomyelitis after placement of a self-expanding plastic stent for palliation of dysphagia associated with chemoradiation-induced esophageal strictures.
Topics: Anti-Bacterial Agents; Carcinoma, Squamous Cell; Cefepime; Cephalosporins; Chemoradiotherapy, Adjuvant; Deglutition Disorders; Esophageal Stenosis; Humans; Male; Middle Aged; Osteomyelitis; Palliative Care; Pharyngeal Neoplasms; Stents; Vancomycin | 2013 |
Inhibitory effects of various essential oils and individual components against extended-spectrum beta-lactamase (ESBL) produced by Klebsiella pneumoniae and their chemical compositions.
Topics: Anti-Bacterial Agents; beta-Lactamase Inhibitors; beta-Lactamases; Cefepime; Cephalosporins; Drug Resistance, Bacterial; Food Preservatives; Gas Chromatography-Mass Spectrometry; Imipenem; Klebsiella pneumoniae; Lamiaceae; Mentha piperita; Microbial Sensitivity Tests; Ocimum basilicum; Ofloxacin; Oils, Volatile; Origanum; Plant Extracts; Satureja | 2011 |
Rates and appropriateness of antimicrobial prescribing at an academic children's hospital, 2007-2010.
Topics: Academic Medical Centers; Adolescent; Anti-Infective Agents; Cefepime; Cephalosporins; Child; Child, Preschool; Drug Utilization; Drug Utilization Review; Female; Hospitals, Pediatric; Humans; Inappropriate Prescribing; Infant; Infant, Newborn; Male; Minnesota; Prescription Drugs; Retrospective Studies; Vancomycin | 2012 |
[Current clinical practice in the treatment of febrile neutropenia (FN)].
Topics: Anti-Bacterial Agents; Cefepime; Cephalosporins; Critical Pathways; Evidence-Based Medicine; Fever; Humans; Japan; Meropenem; Neutropenia; Physicians; Practice Guidelines as Topic; Practice Patterns, Physicians'; Surveys and Questionnaires; Thienamycins | 2011 |
Cefepime for Gram-negative bacteremia in long-term hemodialysis: a single-center experience.
Topics: Adult; Aged; Anti-Bacterial Agents; Bacteremia; Cefepime; Cephalosporins; Chronic Disease; Dose-Response Relationship, Drug; Female; Follow-Up Studies; Gram-Negative Bacterial Infections; Humans; Kidney Diseases; Male; Middle Aged; Renal Dialysis; Retrospective Studies; Treatment Outcome | 2012 |
Role of the two component signal transduction system CpxAR in conferring cefepime and chloramphenicol resistance in Klebsiella pneumoniae NTUH-K2044.
Topics: Amino Acid Sequence; Anti-Bacterial Agents; Bacterial Outer Membrane Proteins; Bacterial Proteins; Base Sequence; beta-Lactam Resistance; Blotting, Western; Cefepime; Cephalosporins; Chloramphenicol; Computational Biology; DNA, Bacterial; Electrophoretic Mobility Shift Assay; Klebsiella Infections; Klebsiella pneumoniae; Microbial Sensitivity Tests; Molecular Sequence Data; Operon; Osmotic Pressure; Oxidative Stress; Protein Kinases; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Bacterial; RNA, Messenger; Sequence Homology, Amino Acid | 2012 |
Chromosome-encoded extended-spectrum class A β-lactamase MIN-1 from Minibacterium massiliensis.
Topics: beta-Lactamases; Cefepime; Cefotaxime; Cephalosporins; Chromosomes, Bacterial; Gram-Positive Bacteria; Molecular Sequence Data; Penicillins | 2012 |
Impact of cefepime therapy on mortality among patients with bloodstream infections caused by extended-spectrum-β-lactamase-producing Klebsiella pneumoniae and Escherichia coli.
Topics: Aged; Aged, 80 and over; Anti-Bacterial Agents; Bacteremia; beta-Lactamases; Cefepime; Cephalosporins; Escherichia coli; Female; Humans; Klebsiella pneumoniae; Male; Middle Aged; Retrospective Studies | 2012 |
Animal model methodology: immunocompetent or leucopenic rats, which is the best? Results from a model of experimental pneumonia due to derepressed cephalosporinase-producing Enterobacter cloacae.
Topics: Amikacin; Animals; Anti-Bacterial Agents; Cefepime; Cephalosporinase; Cephalosporins; Cyclophosphamide; Drug Therapy, Combination; Enterobacter cloacae; Immunocompromised Host; Injections, Intraperitoneal; Leukopenia; Male; Models, Animal; Pneumonia, Bacterial; Rats; Rats, Wistar | 2012 |
Characterization of a novel IMP-28 metallo-β-lactamase from a Spanish Klebsiella oxytoca clinical isolate.
Topics: Amino Acid Sequence; Ampicillin; Anti-Bacterial Agents; Bacterial Proteins; beta-Lactamases; Cefepime; Ceftazidime; Cephalosporins; DNA-Binding Proteins; DNA, Bacterial; Histones; Humans; Imipenem; Integrons; Klebsiella oxytoca; Meropenem; Microbial Sensitivity Tests; Molecular Sequence Data; Mutation; Sequence Alignment; Spain; Thienamycins | 2012 |
[Severely abnormal electroencephalogram in two patients who were treated with cefepime].
Topics: Anti-Bacterial Agents; Brain Diseases; Cefepime; Cephalosporins; Consciousness Disorders; Dyskinesia, Drug-Induced; Electroencephalography; Female; Humans; Kidney Failure, Chronic; Male; Severity of Illness Index | 2012 |
Cefepime: a rare cause of encephalopathy.
Topics: Acute Kidney Injury; Aged; Anti-Bacterial Agents; Cefepime; Cephalosporins; Female; Glomerular Filtration Rate; Humans; Neurotoxicity Syndromes; Osteomyelitis; Pseudomonas Infections; Respiration, Artificial | 2012 |
[Marked reactive plasmacytosis accompanied by drug eruption in a patient with aplastic anemia].
Topics: Anemia, Aplastic; Cefepime; Cephalosporins; Cyclosporine; Dexamethasone; Diagnosis, Differential; Drug Eruptions; Female; Flow Cytometry; Humans; Meropenem; Middle Aged; Plasma Cells; Thienamycins; Treatment Outcome | 2012 |
Extended-spectrum β-lactamase producers reported as susceptible to piperacillin-tazobactam, cefepime, and cefuroxime in the era of lowered breakpoints and no confirmatory tests.
Topics: Anti-Bacterial Agents; beta-Lactamases; Cefepime; Cefuroxime; Cephalosporins; Escherichia coli; Humans; Klebsiella pneumoniae; Microbial Sensitivity Tests; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination | 2012 |
The ecology of antibiotic use in the ICU: homogeneous prescribing of cefepime but not tazocin selects for antibiotic resistant infection.
Topics: Adult; Aged; Anti-Bacterial Agents; Cefepime; Cephalosporins; Drug Prescriptions; Drug Resistance, Bacterial; Female; Humans; Intensive Care Units; Length of Stay; Male; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Middle Aged; Nasopharynx; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Pseudomonas aeruginosa; Pseudomonas Infections; Staphylococcal Infections; Survival Rate | 2012 |
Empiric antibiotics pending bronchoalveolar lavage data in patients without pneumonia significantly alters the flora, but not the resistance profile, if a subsequent pneumonia develops.
Topics: Acetamides; Anti-Bacterial Agents; Bronchoalveolar Lavage; Bronchoalveolar Lavage Fluid; Cefepime; Cephalosporins; Drug Resistance, Bacterial; Drug Therapy, Combination; Female; Gram-Negative Bacteria; Gram-Negative Bacterial Infections; Gram-Positive Bacteria; Gram-Positive Bacterial Infections; Humans; Linezolid; Male; Microbial Sensitivity Tests; Middle Aged; Oxazolidinones; Penicillanic Acid; Piperacillin; Pneumonia, Ventilator-Associated; Retrospective Studies; Tazobactam; Treatment Outcome; Vancomycin; Wounds and Injuries | 2013 |
Red man syndrome adverse reaction following intravenous infusion of cefepime.
Topics: Adult; Anti-Bacterial Agents; Cefepime; Cephalosporins; Drug Hypersensitivity; Erythema; Histamine Antagonists; Humans; Infusions, Intravenous; Male; Meningoencephalitis; Pruritus; Skin | 2012 |
AmpC β-lactamases in nosocomial isolates of Klebsiella pneumoniae from India.
Topics: Anti-Bacterial Agents; Bacterial Proteins; beta-Lactamase Inhibitors; beta-Lactamases; Cefepime; Cephalosporins; Cross Infection; Drug Resistance, Bacterial; Humans; India; Klebsiella pneumoniae; Microbial Sensitivity Tests; Penicillanic Acid; Tazobactam | 2012 |
[Microbiological monitoring in therapy of patients with iatrogenic esophageotracheal fistula].
Topics: Acetamides; Anti-Bacterial Agents; Candida; Cefepime; Cephalosporins; Ciprofloxacin; Drug Resistance, Microbial; Enterobacteriaceae; Follow-Up Studies; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; Iatrogenic Disease; Imipenem; Intubation, Intratracheal; Linezolid; Microbial Sensitivity Tests; Monitoring, Physiologic; Oxazolidinones; Polymyxin B; Pseudomonas aeruginosa; Respiratory Tract Infections; Staphylococcus aureus; Staphylococcus epidermidis; Tracheoesophageal Fistula; Vancomycin | 2012 |
An overlooked cause of impaired consciousness in a hemodialysis patient.
Topics: Aged; Anti-Bacterial Agents; Anticonvulsants; Cefepime; Cephalosporins; Consciousness Disorders; Diabetic Nephropathies; Electroencephalography; Female; Humans; Pneumonia, Bacterial; Renal Dialysis; Status Epilepticus; Treatment Outcome; Uremia | 2012 |
Cutaneous abscess leading to sepsis by Aeromonas hydrophila.
Topics: Abscess; Aeromonas hydrophila; Cefepime; Cephalosporins; Ciprofloxacin; Fever; Gram-Negative Bacterial Infections; Humans; Male; Microbial Sensitivity Tests; Sepsis; Skin Diseases, Bacterial; Young Adult | 2013 |
Antimicrobial susceptibility pattern and distribution of exoU and exoS in clinical isolates of Pseudomonas aeruginosa at a Malaysian hospital.
Topics: ADP Ribose Transferases; Adult; Anti-Bacterial Agents; Bacterial Proteins; Bacterial Toxins; Cefepime; Ceftazidime; Cephalosporins; Chi-Square Distribution; Ciprofloxacin; Drug Resistance, Multiple, Bacterial; Female; Gentamicins; Hospitals; Humans; Malaysia; Male; Microbial Sensitivity Tests; Middle Aged; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Polymerase Chain Reaction; Pseudomonas aeruginosa | 2012 |
Cefepime therapy for monomicrobial bacteremia caused by cefepime-susceptible extended-spectrum beta-lactamase-producing Enterobacteriaceae: MIC matters.
Topics: Aged; Aged, 80 and over; Anti-Bacterial Agents; Bacteremia; beta-Lactamases; Carbapenems; Case-Control Studies; Cefepime; Cephalosporins; Enterobacteriaceae; Enterobacteriaceae Infections; Female; Humans; Male; Middle Aged; Multivariate Analysis; Retrospective Studies; Treatment Outcome | 2013 |
[Demographics, morbidity, and mortality febrile neutropenic adult patients treated with cefepime].
Topics: Adult; Anti-Bacterial Agents; Cefepime; Cephalosporins; Colombia; Comorbidity; Cross-Sectional Studies; Demography; Febrile Neutropenia; Female; Humans; Male; Middle Aged | 2012 |
Pediatric cefepime neurotoxicity.
Topics: Acute Kidney Injury; Adolescent; Anti-Bacterial Agents; Cefepime; Cephalosporins; Female; Humans; Neurotoxicity Syndromes | 2012 |
Case-control study of drug monitoring of β-lactams in obese critically ill patients.
Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Bacterial Infections; beta-Lactams; Case-Control Studies; Cefepime; Ceftazidime; Cephalosporins; Drug Monitoring; Enzyme Inhibitors; Female; Humans; Male; Meropenem; Middle Aged; Obesity; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Renal Replacement Therapy; Sepsis; Shock, Septic; Tazobactam; Thienamycins; Young Adult | 2013 |
Diagnosis of acute deer tick virus encephalitis.
Topics: Aged; Animals; Anti-Bacterial Agents; Cefepime; Cephalosporins; Diagnosis, Differential; Encephalitis Viruses, Tick-Borne; Encephalitis, Tick-Borne; Fatal Outcome; Humans; Ixodes; Magnetic Resonance Imaging; Male; New York; Phylogeny; Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction | 2013 |
Therapeutic drug monitoring when using cefepime in continuous renal replacement therapy: seizures associated with cefepime.
Topics: Aged, 80 and over; Anti-Bacterial Agents; Cefepime; Cephalosporins; Drug Monitoring; Hemofiltration; Humans; Male; Metabolic Clearance Rate; Neurotoxicity Syndromes; Pneumonia; Seizures; Shock, Septic | 2012 |
Characterisation and clinical features of Enterobacter cloacae bloodstream infections occurring at a tertiary care university hospital in Switzerland: is cefepime adequate therapy?
Topics: Adult; Aged; Anti-Bacterial Agents; Bacteremia; beta-Lactamases; Cefepime; Cephalosporins; Drug Therapy, Combination; Enterobacter cloacae; Enterobacteriaceae Infections; Female; Genotype; Hospitals, University; Humans; Infections; Male; Microbial Sensitivity Tests; Middle Aged; Molecular Typing; Survival Analysis; Switzerland; Tertiary Care Centers; Treatment Outcome | 2013 |
A positive interaction between inhibitors of protein synthesis and cefepime in the fight against methicillin-resistant Staphylococcus aureus.
Topics: Anti-Bacterial Agents; Cefepime; Cephalosporins; Drug Synergism; Microbial Sensitivity Tests; Protein Synthesis Inhibitors; Staphylococcus aureus | 2013 |
The safety of cefepime and ceftazidime in pediatric oncology patients.
Topics: Adolescent; Anti-Bacterial Agents; Bacterial Infections; Cefepime; Ceftazidime; Cephalosporins; Child; Child, Preschool; Coinfection; Female; Humans; Infant; Infant, Newborn; Male; Neoplasms; Retrospective Studies; Treatment Failure; Treatment Outcome; Young Adult | 2013 |
Optic nerve involvement from Pseudomonas aeruginosa -associated skull base osteomyelitis.
Topics: Aged; Anti-Bacterial Agents; Blindness; Cefepime; Cephalosporins; Eye Infections, Bacterial; Humans; Magnetic Resonance Imaging; Male; Meropenem; Middle Aged; Optic Nerve Diseases; Osteomyelitis; Pseudomonas aeruginosa; Pseudomonas Infections; Skull Base; Thienamycins; Visual Acuity | 2013 |
Repeated colonization by multi-drug-resistant Acinetobacter calcoaceticus-A. baumannii complex and changes in antimicrobial susceptibilities in surgical intensive care units.
Topics: Acinetobacter; Acinetobacter Infections; Anti-Bacterial Agents; Cefepime; Cephalosporins; Chi-Square Distribution; China; Cilastatin; Cilastatin, Imipenem Drug Combination; Critical Care; Cross Infection; Disease Outbreaks; Drug Combinations; Drug Resistance, Multiple, Bacterial; Electrophoresis, Gel, Pulsed-Field; Humans; Imipenem; Microbial Sensitivity Tests; Public Health Surveillance; Retrospective Studies | 2013 |
Comparative study on resistant pattern of clinical isolates against levofloxacin and cefepime.
Topics: Bacteria; Cefepime; Cephalosporins; Disk Diffusion Antimicrobial Tests; Drug Resistance, Multiple, Bacterial; Humans; Levofloxacin; Ofloxacin | 2013 |
Detection of ESBL among AmpC producing enterobacteriaceae using inhibitor-based method.
Topics: Anti-Bacterial Agents; Bacterial Proteins; beta-Lactam Resistance; beta-Lactamase Inhibitors; beta-Lactamases; Body Fluids; Boronic Acids; Cefepime; Cefoxitin; Cephalosporin Resistance; Cephalosporins; Clavulanic Acid; Disk Diffusion Antimicrobial Tests; Enterobacteriaceae; Enterobacteriaceae Infections; Enzyme Induction; Gene Expression Regulation, Bacterial; Humans; Substrate Specificity | 2013 |
Effectiveness of early haemodialysis in cefepime-induced neurotoxicity.
Topics: Aged; Anti-Bacterial Agents; Cefepime; Cephalosporins; Early Medical Intervention; Humans; Male; Neurotoxicity Syndromes; Renal Dialysis; Treatment Outcome | 2013 |
Risk factors and mortality of patients with nosocomial carbapenem-resistant Acinetobacter baumannii pneumonia.
Topics: Acinetobacter baumannii; Acinetobacter Infections; Aged; Anti-Bacterial Agents; beta-Lactam Resistance; Carbapenems; Cefepime; Cephalosporins; Cohort Studies; Cross Infection; Disease Susceptibility; Drug Resistance, Multiple, Bacterial; Female; Humans; Male; Middle Aged; Outcome Assessment, Health Care; Pneumonia; Retrospective Studies; Risk Factors | 2013 |
A unique case of peroneus brevis/longus myositis in a patient with a STAT3 mutation.
Topics: Adult; Anti-Bacterial Agents; Bacterial Infections; Cefepime; Cephalosporins; Disease-Free Survival; Humans; Job Syndrome; Male; Muscles; Mutation; Myositis; Recurrence; STAT3 Transcription Factor; Vancomycin | 2013 |
Drug use evaluation of cefepime in the first affiliated hospital of Bengbu medical college: a retrospective and prospective analysis.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Attitude of Health Personnel; Behavior Therapy; Cefepime; Cephalosporins; Child; Child, Preschool; China; Cohort Studies; Cost-Benefit Analysis; Drug Utilization Review; Education, Medical; Female; Hospitals; Humans; Infant; Male; Middle Aged; Prospective Studies; Retrospective Studies; Young Adult | 2013 |
Extended-infusion cefepime reduces mortality in patients with Pseudomonas aeruginosa infections.
Topics: Aged; Anti-Bacterial Agents; Cefepime; Cephalosporins; Drug Administration Schedule; Female; Humans; Intensive Care Units; Male; Middle Aged; Pseudomonas aeruginosa; Pseudomonas Infections; Retrospective Studies | 2013 |
Concomitant typhlitis and Clostridium difficile colitis developed after first R-CHOP chemotherapy in a non-Hodgkin lymphoma patient.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combined Chemotherapy Protocols; Cefepime; Cephalosporins; Clostridioides difficile; Cyclophosphamide; Doxorubicin; Drug Therapy, Combination; Enterocolitis, Pseudomembranous; Humans; Lymphoma, Non-Hodgkin; Male; Metronidazole; Middle Aged; Polymerase Chain Reaction; Prednisone; Radiography; Rituximab; Typhlitis; Vancomycin; Vincristine | 2013 |
Klebsiella pneumoniae carbapenemase-producing Enterobacteriaceae testing susceptible to cefepime by reference methods.
Topics: Anti-Bacterial Agents; Bacterial Proteins; beta-Lactamases; Cefepime; Cephalosporins; Enterobacteriaceae; Humans; Microbial Sensitivity Tests | 2013 |
Evaluation of MicroScan WalkAway and Vitek 2 for determination of the susceptibility of extended-spectrum β-lactamase-producing Escherichia coli and Klebsiella pneumoniae isolates to cefepime, cefotaxime and ceftazidime.
Topics: Automation, Laboratory; beta-Lactamases; Cefepime; Cefotaxime; Ceftazidime; Cephalosporins; Diagnostic Errors; DNA, Bacterial; Escherichia coli; Genotype; Hospitals; Humans; Klebsiella pneumoniae; Korea; Microbial Sensitivity Tests; Polymerase Chain Reaction | 2013 |
Physical compatibility of sodium citrate with alcohol and cefepime.
Topics: Cefepime; Cephalosporins; Citrates; Equipment Contamination; Ethanol; Humans; Pharmaceutical Solutions; Sodium Citrate | 2013 |
Comparison of the prevalence of convulsions associated with the use of cefepime and meropenem.
Topics: Adult; Aged; Anti-Bacterial Agents; Brain Diseases; Cefepime; Cephalosporins; Female; Hospitals, University; Humans; Infusions, Intravenous; Japan; Male; Meropenem; Neurotoxicity Syndromes; Prevalence; Pseudomonas aeruginosa; Pseudomonas Infections; Renal Insufficiency; Retrospective Studies; Risk; Seizures; Staphylococcal Infections; Staphylococcus aureus; Thienamycins | 2013 |
The use of cefepime for treating AmpC β-lactamase-producing Enterobacteriaceae.
Topics: Adult; Anti-Bacterial Agents; Bacterial Proteins; beta-Lactam Resistance; beta-Lactamases; Cefepime; Cephalosporins; Cohort Studies; Enterobacteriaceae; Enterobacteriaceae Infections; Hospitalization; Humans; Meropenem; Microbial Sensitivity Tests; Middle Aged; Propensity Score; Thienamycins | 2013 |
Clinical characteristics and antimicrobial susceptibilities of viridans streptococcal bacteremia during febrile neutropenia in patients with hematologic malignancies: a comparison between adults and children.
Topics: Adult; Age Factors; Anti-Bacterial Agents; Bacteremia; Cefepime; Cephalosporins; Febrile Neutropenia; Female; Hematologic Neoplasms; Humans; Male; Microbial Sensitivity Tests; Middle Aged; Multivariate Analysis; Streptococcal Infections; Viridans Streptococci | 2013 |
Cefepime-induced nonconvulsive status epilepticus as a cause of confusion in an elderly patient.
Topics: Aged, 80 and over; Anti-Bacterial Agents; Cefepime; Cephalosporins; Confusion; Cross Infection; Electroencephalography; Humans; Male; Status Epilepticus | 2015 |
When pharmacodynamics trump costs: an antimicrobial stewardship program's approach to selecting optimal antimicrobial agents.
Topics: Adult; Anti-Bacterial Agents; Carbapenems; Cefepime; Cephalosporins; Doripenem; Drug Costs; Humans; Imipenem; Meropenem; Microbial Sensitivity Tests; Monte Carlo Method; Pseudomonas aeruginosa; Pseudomonas Infections; Thienamycins | 2013 |
An MEKC assay for the therapeutic drug monitoring of cefepime.
Topics: Anti-Bacterial Agents; Calibration; Cefepime; Cephalosporins; Chromatography, Micellar Electrokinetic Capillary; Drug Monitoring; Humans; Quality Control | 2013 |
New insights in the production of aerosol antibiotics. Evaluation of the optimal aerosol production system for ampicillin-sulbactam, meropenem, ceftazidime, cefepime and piperacillin-tazobactam.
Topics: Aerosols; Ampicillin; Anti-Bacterial Agents; Cefepime; Ceftazidime; Cephalosporins; Chemistry, Pharmaceutical; Equipment Design; Meropenem; Nebulizers and Vaporizers; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Sulbactam; Thienamycins | 2013 |
Risk factors of fecal toxigenic or non-toxigenic Clostridium difficile colonization: impact of Toll-like receptor polymorphisms and prior antibiotic exposure.
Topics: Aged; Aged, 80 and over; Anti-Infective Agents; Cefepime; Cefuroxime; Cephalosporins; Clostridioides difficile; Enterocolitis, Pseudomembranous; Feces; Female; Humans; Male; Metronidazole; Middle Aged; Odds Ratio; Polymorphism, Genetic; Risk Factors; Toll-Like Receptor 4; Vancomycin | 2013 |
Relationship between the distribution of cefepime minimum inhibitory concentrations and detection of extended-spectrum β-lactamase production among clinically important Enterobacteriaceae isolates obtained from patients in intensive care units in Taiwan:
Topics: Anti-Bacterial Agents; beta-Lactamases; Cefepime; Cefotaxime; Ceftazidime; Cephalosporin Resistance; Cephalosporins; Enterobacteriaceae; Enterobacteriaceae Infections; Epidemiological Monitoring; Humans; Intensive Care Units; Microbial Sensitivity Tests; Taiwan | 2015 |
Efficacy of Ceftaroline Fosamil against Escherichia coli and Klebsiella pneumoniae strains in a rabbit meningitis model.
Topics: Animals; Anti-Bacterial Agents; Cefepime; Ceftaroline; Cephalosporins; Disease Models, Animal; Escherichia coli; Klebsiella Infections; Klebsiella pneumoniae; Meninges; Meningitis, Escherichia coli; Permeability; Rabbits; Treatment Outcome | 2013 |
Impact of antibiotic use during hospitalization on the development of gastrointestinal colonization with Escherichia coli with reduced fluoroquinolone susceptibility.
Topics: Aged; Anti-Bacterial Agents; Carrier State; Cefepime; Cephalosporins; Drug Resistance, Bacterial; Escherichia coli; Escherichia coli Infections; Feces; Female; Fluoroquinolones; Gastrointestinal Tract; Hospitalization; Humans; Length of Stay; Male; Middle Aged; Neoplasms; Prospective Studies; Risk Factors | 2013 |
Clinical characteristics and risk factors for mortality in cefepime-resistant Pseudomonas aeruginosa bacteremia.
Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Bacteremia; beta-Lactam Resistance; Cefepime; Cephalosporins; Female; Humans; Male; Middle Aged; Pseudomonas aeruginosa; Pseudomonas Infections; Retrospective Studies; Risk Factors; Severity of Illness Index; Survival Analysis | 2015 |
Comparison of efficiency of intravitreal ceftazidime and intravitreal cefepime in the treatment of experimental Pseudomonas aeruginosa endophthalmitis.
Topics: Animals; Anti-Bacterial Agents; Cefepime; Ceftazidime; Cephalosporins; Disease Models, Animal; Endophthalmitis; Eye Infections, Bacterial; Pseudomonas aeruginosa; Pseudomonas Infections; Rabbits; Treatment Outcome; Vitreous Body | 2013 |
Acute renal failure associated with vancomycin and β-lactams for the treatment of osteomyelitis in diabetics: piperacillin-tazobactam as compared with cefepime.
Topics: Acute Kidney Injury; Anti-Bacterial Agents; Cefepime; Cephalosporins; Cohort Studies; Diabetes Complications; Drug Therapy, Combination; Humans; Incidence; Middle Aged; Osteomyelitis; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Retrospective Studies; Vancomycin | 2014 |
Continuous versus intermittent infusion of cefepime in neurosurgical patients with post-operative intracranial infections.
Topics: Adult; Aged; Anti-Bacterial Agents; Cefepime; Cephalosporins; Female; Humans; Infusions, Intravenous; Male; Meningitis, Bacterial; Middle Aged; Neurosurgical Procedures; Plasma; Postoperative Complications; Retrospective Studies | 2014 |
The impact of cefepime as first line therapy for neutropenic fever on Clostridium difficile rates among hematology and oncology patients.
Topics: Anti-Bacterial Agents; Cefepime; Cephalosporins; Clostridioides difficile; Clostridium Infections; Fever of Unknown Origin; Hematologic Neoplasms; Humans; Neutropenia; Retrospective Studies | 2013 |
Usefulness of bilateral bispectral index (BIS) monitoring in a comatose patient with myoclonic status epilepticus secondary to cefepime.
Topics: Cefepime; Cephalosporins; Coma; Electroencephalography; Fatal Outcome; Humans; Male; Middle Aged; Monitoring, Physiologic; Status Epilepticus | 2013 |
Postoperative bacteriuria, pyuria and urinary tract infection in patients with an orthotopic sigmoid colon neobladder replacement.
Topics: Aged; Anti-Bacterial Agents; Bacteriuria; Cefepime; Cephalosporins; Colon, Sigmoid; Cystectomy; Drug Resistance, Multiple, Bacterial; Enterococcus; Escherichia coli; Female; Humans; Klebsiella pneumoniae; Leukocyte Count; Levofloxacin; Male; Meropenem; Middle Aged; Penicillanic Acid; Piperacillin; Postoperative Complications; Prevalence; Pyuria; Staphylococcus aureus; Sulfamethoxazole; Tazobactam; Thienamycins; Trimethoprim; Urinary Diversion; Urinary Tract Infections | 2014 |
Cefepime neurotoxicity in the intensive care unit: a cause of severe, underappreciated encephalopathy.
Topics: Aged; Anti-Bacterial Agents; Cefepime; Cephalosporins; Consciousness Disorders; Delirium; Female; Humans; Intensive Care Units; Male; Medical Records; Minnesota; Myoclonus; Neurotoxicity Syndromes; Renal Insufficiency, Chronic; Retrospective Studies | 2013 |
Treatment of Rhizobium radiobacter bacteremia in a critically ill trauma patient.
Topics: Adult; Agrobacterium tumefaciens; Anti-Bacterial Agents; Bacteremia; Cefepime; Cephalosporins; Critical Illness; Female; Humans; Opportunistic Infections; Treatment Outcome; Wounds and Injuries | 2013 |
Treatment of Chryseobacterium indologenes ventilator-associated pneumonia in a critically ill trauma patient.
Topics: Aged; Anti-Bacterial Agents; Aza Compounds; Cefepime; Cephalosporins; Chryseobacterium; Critical Illness; Flavobacteriaceae Infections; Fluoroquinolones; Humans; Intensive Care Units; Male; Moxifloxacin; Pneumonia, Ventilator-Associated; Quinolines; Radiography; Wounds and Injuries | 2013 |
Treatment of KPC-2 Enterobacter cloacae empyema with cefepime and levofloxacin.
Topics: Anti-Bacterial Agents; beta-Lactamases; Cefepime; Cephalosporins; Drug Therapy, Combination; Empyema; Enterobacter cloacae; Enterobacteriaceae Infections; Humans; Levofloxacin; Male; Middle Aged; Treatment Outcome | 2014 |
Reliability-targeted HPLC-UV method validation--a protocol enrichment perspective.
Topics: Bayes Theorem; Cefepime; Cephalosporins; Chromatography, High Pressure Liquid; Humans; Penicillanic Acid; Reproducibility of Results; Ritonavir; Spectrophotometry, Ultraviolet; Tazobactam | 2014 |
Clinical pharmacodynamics of antipseudomonal cephalosporins in patients with ventilator-associated pneumonia.
Topics: Anti-Bacterial Agents; Cefepime; Ceftazidime; Cephalosporins; Enterobacteriaceae Infections; Female; Humans; Male; Microbial Sensitivity Tests; Middle Aged; Pneumonia, Ventilator-Associated; Pseudomonas Infections; Retrospective Studies | 2014 |
Effect of cefepime dose on mortality of patients with Gram-negative bacterial bloodstream infections: a prospective cohort study.
Topics: Adult; Aged; Anti-Bacterial Agents; Bacteremia; Cefepime; Cephalosporins; Drug Resistance, Bacterial; Drug Substitution; Female; Gram-Negative Bacteria; Gram-Negative Bacterial Infections; Hospital Mortality; Humans; Male; Microbial Sensitivity Tests; Middle Aged; Prospective Studies; Risk Factors; Treatment Outcome | 2014 |
Cefepime-induced encephalopathy in patients with haematological malignancies: clinical features and risk factors.
Topics: Aged; Aged, 80 and over; Brain Diseases; Cefepime; Cephalosporins; Electroencephalography; Female; Hematologic Neoplasms; Humans; Male; Middle Aged; Renal Insufficiency; Retrospective Studies; ROC Curve | 2014 |
Late manifestation of a driveline infection after heart transplantation.
Topics: Abdomen; Anti-Bacterial Agents; Cefepime; Cephalosporins; Debridement; Device Removal; Female; Heart Failure; Heart Transplantation; Heart-Assist Devices; Humans; Middle Aged; Polyethylene Terephthalates; Proteus Infections; Pseudomonas Infections; Radiography, Abdominal; Surgical Wound Infection; Time Factors; Tomography, X-Ray Computed; Treatment Outcome | 2014 |
CTX-M-producing Escherichia coli in Lithuania: associations between sites of infection, coresistance, and phylogenetic groups.
Topics: Anti-Bacterial Agents; beta-Lactamases; Cefepime; Cephalosporins; Drug Resistance, Multiple, Bacterial; Escherichia coli; Escherichia coli Infections; Galanin; Gentamicins; Humans; Lithuania; Phylogeny; Substance P | 2013 |
The lack of specificity of tracheal aspirates in the diagnosis of pulmonary infection in intubated children.
Topics: Anti-Bacterial Agents; Catheters; Cefepime; Cephalosporins; Child, Preschool; Colony Count, Microbial; Female; Humans; Infant; Infant, Newborn; Intensive Care Units, Pediatric; Intubation, Intratracheal; Male; Neutrophils; Pneumonia, Bacterial; Pneumonia, Ventilator-Associated; Prospective Studies; Respiration, Artificial; Time Factors; Trachea | 2014 |
Treatment failure due to induction of ciprofloxacin resistance during combination therapy with colistin and ciprofloxacin in multidrug-resistant Pseudomonas aeruginosa bacteraemia.
Topics: Adult; Anti-Bacterial Agents; Bacteremia; Cefepime; Cephalosporins; Ciprofloxacin; Colistin; Drug Resistance, Multiple, Bacterial; Drug Therapy, Combination; Female; Humans; Immunocompromised Host; Meropenem; Pseudomonas aeruginosa; Pseudomonas Infections; Thienamycins; Tobramycin; Treatment Failure | 2014 |
Cefepime vs other antibacterial agents for the treatment of Enterobacter species bacteremia.
Topics: Aged; Anti-Bacterial Agents; Bacteremia; Carbapenems; Cefepime; Cephalosporins; Enterobacter; Enterobacteriaceae Infections; Female; Humans; Male; Middle Aged; Survival Analysis; Treatment Outcome | 2014 |
Facing the challenges of new melanoma-targeted therapies: Treatment of severe fevers associated with dabrafenib/trametinib combination therapy.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Cefepime; Cephalosporins; Drug Delivery Systems; Female; Fever; Humans; Imidazoles; Melanoma; Oximes; Pyridones; Pyrimidinones; Severity of Illness Index | 2015 |
Feasibility, efficacy, and adverse effects of outpatient antibacterial prophylaxis in children with acute myeloid leukemia.
Topics: Administration, Oral; Adolescent; Anti-Bacterial Agents; Antibiotic Prophylaxis; Bacteremia; Bacterial Infections; Candidiasis; Cefepime; Cephalosporins; Chemotherapy-Induced Febrile Neutropenia; Child; Child, Preschool; Ciprofloxacin; Consolidation Chemotherapy; Drug Therapy, Combination; Feasibility Studies; Female; Humans; Incidence; Induction Chemotherapy; Infant; Infusions, Intravenous; Leukemia, Myeloid, Acute; Male; Neoplasm Staging; Nose; Outpatients; Rectum; Retrospective Studies; Treatment Outcome; Vancomycin; Young Adult | 2014 |
Comparative evaluation of six phenotypic methods for detecting extended-spectrum beta-lactamase-producing Enterobacteriaceae.
Topics: Amoxicillin-Potassium Clavulanate Combination; Anti-Bacterial Agents; Bacterial Typing Techniques; beta-Lactamases; beta-Lactams; Cefepime; Cefotaxime; Ceftazidime; Cephalosporins; Enterobacteriaceae; False Negative Reactions; False Positive Reactions; Female; Humans; India; Male; Microbial Sensitivity Tests; Penicillanic Acid; Phenotype; Piperacillin; Piperacillin, Tazobactam Drug Combination; Predictive Value of Tests | 2014 |
Unacceptably high error rates in Vitek 2 testing of cefepime susceptibility in extended-spectrum-β-lactamase-producing Escherichia coli.
Topics: Anti-Bacterial Agents; beta-Lactamases; Cefepime; Cephalosporins; Escherichia coli; Escherichia coli Infections; Genes, Bacterial; Microbial Sensitivity Tests; Polymerase Chain Reaction; Reproducibility of Results | 2014 |
Comparison of acute kidney injury during treatment with vancomycin in combination with piperacillin-tazobactam or cefepime.
Topics: Acute Kidney Injury; Adult; Aged; Anti-Bacterial Agents; Cefepime; Cephalosporins; Cohort Studies; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Retrospective Studies; Treatment Outcome; Vancomycin | 2014 |
Antimicrobial activity of cefepime-tazobactam combination tested against clinical isolates of Enterobacteriaceae.
Topics: Anti-Bacterial Agents; Cefepime; Cephalosporins; Drug Resistance, Bacterial; Drug Therapy, Combination; Enterobacteriaceae; Humans; India; Penicillanic Acid; Tazobactam | 2014 |
Convulsive liability of cefepime and meropenem in normal and corneal kindled mice.
Topics: Animals; Anti-Bacterial Agents; Cefepime; Cephalosporins; Convulsants; Disease Susceptibility; Drug Administration Schedule; Electroencephalography; Electroshock; Injections, Intravenous; Male; Meropenem; Mice; Mice, Inbred ICR; Pentylenetetrazole; Seizures; Severity of Illness Index; Species Specificity; Thienamycins | 2014 |
Epidemic and virulence characteristic of Shigella spp. with extended-spectrum cephalosporin resistance in Xiaoshan District, Hangzhou, China.
Topics: Adolescent; Adult; Anti-Bacterial Agents; beta-Lactamases; Cefepime; Cephalosporin Resistance; Cephalosporins; Child; Child, Preschool; China; Ciprofloxacin; Dysentery, Bacillary; Female; Galanin; Genes, Bacterial; Genotype; Humans; Male; Microbial Sensitivity Tests; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Polymerase Chain Reaction; Shigella; Substance P; Virulence | 2014 |
His224 alters the R2 drug binding site and Phe218 influences the catalytic efficiency of the metallo-β-lactamase VIM-7.
Topics: Amino Acid Substitution; Anti-Bacterial Agents; Aspartic Acid; beta-Lactam Resistance; beta-Lactamases; Binding Sites; Biocatalysis; Cefepime; Ceftazidime; Cephalosporins; Endopeptidases; Enzyme Stability; Escherichia coli; Gene Expression; Histidine; Hot Temperature; Hydrogen Bonding; Molecular Docking Simulation; Phenylalanine; Protein Binding; Pseudomonas aeruginosa; Recombinant Fusion Proteins; Static Electricity; Structure-Activity Relationship | 2014 |
Osteomyelitis of the clavicle following to a pacemaker implantation.
Topics: Anti-Bacterial Agents; Cardiac Pacing, Artificial; Cefepime; Cephalosporins; Ciprofloxacin; Clavicle; Drug Therapy, Combination; Equipment Design; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Osteomyelitis; Pacemaker, Artificial; Pseudomonas aeruginosa; Pseudomonas Infections | 2014 |
[Mechanism of drug resistance of carbapenems-resistant Acinetobacter baumannii and the application of a combination of drugs in vitro].
Topics: Acinetobacter baumannii; Acinetobacter Infections; Ampicillin; Anti-Bacterial Agents; beta-Lactamase Inhibitors; Carbapenems; Cefepime; Cephalosporins; Drug Resistance; Humans; In Vitro Techniques; Meropenem; Microbial Sensitivity Tests; Penicillanic Acid; Pharmaceutical Preparations; Piperacillin; Piperacillin, Tazobactam Drug Combination; Sulbactam; Thienamycins | 2014 |
A degradation study of cefepime hydrochloride in solutions under various stress conditions by TLC-densitometry.
Topics: Cefepime; Cephalosporins; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Densitometry; Drug Stability; Hydrogen-Ion Concentration; Kinetics; Limit of Detection; Pyrrolidines; Reproducibility of Results; Sensitivity and Specificity; Solutions; Tandem Mass Spectrometry; Temperature; Thermodynamics | 2015 |
Stimulus-induced Rhythmic, Periodic, or Ictal Discharges (SIRPDs) associated with seizures in cefepime neurotoxicity.
Topics: Anti-Bacterial Agents; Cefepime; Cephalosporins; Electroencephalography; Humans; Periodicity; Seizures | 2014 |
Susceptibility of Escherichia coli from community-acquired urinary tract infection to fosfomycin, nitrofurantoin, and temocillin in Korea.
Topics: Anti-Bacterial Agents; Cefepime; Cell Survival; Cephalosporins; Ciprofloxacin; Community-Acquired Infections; Dose-Response Relationship, Drug; Drug Combinations; Drug Resistance, Bacterial; Escherichia coli; Escherichia coli Infections; Fosfomycin; Humans; Nitrofurantoin; Penicillins; Republic of Korea; Sulfadoxine; Treatment Outcome; Trimethoprim; Urinary Tract Infections | 2014 |
The impact of an antimicrobial stewardship programme on the use of antimicrobials and the evolution of drug resistance.
Topics: Anti-Bacterial Agents; Bacterial Infections; Cefepime; Cephalosporins; Drug Resistance, Microbial; Drug Utilization; Humans; Imipenem; Klebsiella pneumoniae; Meropenem; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Pharmacy Service, Hospital; Practice Patterns, Physicians'; Program Evaluation; Pseudomonas aeruginosa; Spain; Thienamycins | 2015 |
Mutation-driven β-lactam resistance mechanisms among contemporary ceftazidime-nonsusceptible Pseudomonas aeruginosa isolates from U.S. hospitals.
Topics: Anti-Bacterial Agents; Bacterial Outer Membrane Proteins; Bacterial Proteins; beta-Lactam Resistance; beta-Lactamases; Cefepime; Ceftazidime; Cephalosporins; Cross Infection; Gene Expression Regulation, Bacterial; Humans; Membrane Transport Proteins; Microbial Sensitivity Tests; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Porins; Pseudomonas aeruginosa; Pseudomonas Infections | 2014 |
[Correlation between the biofilm-forming ability, biofilm-related genes and antimicrobial resistance of Acinetobacter baumannii].
Topics: Acinetobacter baumannii; Anti-Bacterial Agents; Biofilms; Cefepime; Cephalosporins; Drug Resistance, Bacterial; Meropenem; Piperacillin; Prospective Studies; Thienamycins | 2014 |
Fatal disseminated infection with Fusarium petroliphilum.
Topics: Amphotericin B; Antifungal Agents; Cefepime; Cephalosporins; Clarithromycin; Drug Resistance, Fungal; Female; Fusariosis; Fusarium; Humans; Levofloxacin; Microbial Sensitivity Tests; Middle Aged; Multilocus Sequence Typing; Mycological Typing Techniques; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Trimethoprim, Sulfamethoxazole Drug Combination | 2015 |
Clinical comparison of ertapenem and cefepime for treatment of infections caused by AmpC beta-lactamase-producing Enterobacteriaceae.
Topics: Aged; Anti-Bacterial Agents; Bacterial Proteins; beta-Lactam Resistance; beta-Lactamases; beta-Lactams; Case-Control Studies; Cefepime; Cephalosporins; Enterobacteriaceae; Enterobacteriaceae Infections; Ertapenem; Female; Hospitalization; Humans; Male; Middle Aged; Retrospective Studies; Treatment Outcome | 2014 |
Quantification of piperacillin, tazobactam, cefepime, meropenem, ciprofloxacin and linezolid in serum using an isotope dilution UHPLC-MS/MS method with semi-automated sample preparation.
Topics: Analytic Sample Preparation Methods; Anti-Bacterial Agents; Automation; Blood Chemical Analysis; Cefepime; Cephalosporins; Chromatography, High Pressure Liquid; Ciprofloxacin; Humans; Isotopes; Linezolid; Meropenem; Penicillanic Acid; Piperacillin; Tandem Mass Spectrometry; Tazobactam; Thienamycins; Time Factors | 2015 |
Hydrophilic polymer microemboli in a patient with a chronic cutaneous ulcer: a case report.
Topics: Anti-Bacterial Agents; Cefepime; Cephalosporins; Coated Materials, Biocompatible; Embolism; Foreign Bodies; Humans; Leg Ulcer; Male; Middle Aged | 2014 |
Identification of optimal renal dosage adjustments for high-dose extended-infusion cefepime dosing regimens in hospitalized patients.
Topics: Anti-Bacterial Agents; Cefepime; Cephalosporins; Humans; Infusions, Intravenous; Inpatients; Kidney; Monte Carlo Method; Time Factors | 2015 |
Extended-spectrum β-lactamase-producing Escherichia coli and Klebsiella pneumoniae bacteremia in febrile neutropenic children.
Topics: Aminoglycosides; Anti-Bacterial Agents; Bacteremia; beta-Lactamases; Cefepime; Cephalosporins; Child; Escherichia coli; Escherichia coli Infections; Febrile Neutropenia; Female; Humans; Klebsiella Infections; Klebsiella pneumoniae; Male; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Retrospective Studies | 2015 |
Efficacy of cefepime, ertapenem and norfloxacin against leptospirosis and for the clearance of pathogens in a hamster model.
Topics: Animal Structures; Animals; Anti-Bacterial Agents; beta-Lactams; Cefepime; Cephalosporins; Cricetinae; Disease Models, Animal; Ertapenem; Histocytochemistry; Leptospira interrogans serovar autumnalis; Leptospirosis; Norfloxacin; Survival Analysis; Treatment Outcome | 2014 |
Characterization of resistance genes in 68 ESBL-producing Klebsiella pneumonia in Lebanon.
Topics: Anti-Bacterial Agents; beta-Lactamases; Carbapenems; Cefepime; Cephalosporins; Colony Count, Microbial; Disk Diffusion Antimicrobial Tests; Drug Resistance, Multiple, Bacterial; Genes, Bacterial; Humans; Klebsiella Infections; Klebsiella pneumoniae; Lebanon; Microbial Sensitivity Tests; Organ Specificity; Substrate Specificity | 2014 |
Evaluation of the efficiency of cefoxitin/cefepime combination against Enterobacteriaceae resistant to expanded-spectrum cephalosporins.
Topics: Animal Structures; Animals; Bacterial Load; beta-Lactam Resistance; beta-Lactamases; Cefepime; Cefoxitin; Cephalosporins; Disease Models, Animal; Drug Interactions; Drug Therapy, Combination; Enterobacteriaceae; Enterobacteriaceae Infections; Humans; Mice; Microbial Sensitivity Tests; Survival Analysis; Treatment Outcome | 2015 |
Efficacy of anti-pseudomonal antibiotics: need to reconsider the empirical use of cefepime.
Topics: Aged; Aged, 80 and over; Cefepime; Cephalosporins; Cross Infection; Drug Resistance, Bacterial; Female; Humans; Male; Middle Aged; Pseudomonas aeruginosa; Pseudomonas Infections | 2014 |
Secular trends associated with Enterobacteriaceae with a cefepime susceptible-dose-dependent MIC.
Topics: Cefepime; Cephalosporins; Enterobacteriaceae; Enterobacteriaceae Infections; Humans; Microbial Sensitivity Tests | 2015 |
Human serum paraoxonase-1 (hPON1): in vitro inhibition effects of moxifloxacin hydrochloride, levofloxacin hemihidrate, cefepime hydrochloride, cefotaxime sodium and ceftizoxime sodium.
Topics: Aryldialkylphosphatase; Cefepime; Cefotaxime; Ceftizoxime; Cephalosporins; Fluoroquinolones; Humans; In Vitro Techniques; Levofloxacin; Moxifloxacin | 2015 |
Treatment of multidrug-resistant pseudomonas aeruginosa using extended-infusion antimicrobial regimens.
Topics: Adult; Anti-Bacterial Agents; Cefepime; Cephalosporins; Colistin; Dose-Response Relationship, Drug; Drug Resistance, Multiple, Bacterial; Drug Therapy, Combination; Female; Heart-Assist Devices; Humans; Infusions, Intravenous; Metabolic Clearance Rate; Microbial Sensitivity Tests; Pseudomonas aeruginosa; Pseudomonas Infections; Renal Dialysis; Time Factors; Treatment Outcome | 2015 |
A single-center evaluation of the risk for colonization or bacteremia with piperacillin-tazobactam- and cefepime-resistant bacteria in patients with acute leukemia receiving fluoroquinolone prophylaxis.
Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Bacteremia; Cefepime; Cephalosporins; Drug Resistance, Bacterial; Female; Fluoroquinolones; Humans; Leukemia; Male; Middle Aged; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Post-Exposure Prophylaxis; Random Allocation; Retrospective Studies; Risk Factors; Young Adult | 2016 |
Application of Savitzky-Golay differentiation filters and Fourier functions to simultaneous determination of cefepime and the co-administered drug, levofloxacin, in spiked human plasma.
Topics: Cefepime; Cephalosporins; Fourier Analysis; Humans; Levofloxacin; Models, Molecular; Solutions; Spectrophotometry, Ultraviolet | 2015 |
Images in emergency medicine. Acute generalized exanthematous pustulosis.
Topics: Acute Generalized Exanthematous Pustulosis; Anti-Bacterial Agents; Cefepime; Cephalosporins; Female; Humans; Middle Aged; Vancomycin | 2015 |
Trust me, this is the worst "acne" of your life!
Topics: Acute Generalized Exanthematous Pustulosis; Anti-Bacterial Agents; Cefepime; Cephalosporins; Diagnosis, Differential; Drug Eruptions; Female; Humans; Middle Aged; Vancomycin | 2015 |
Implementing extended-infusion cefepime as standard of care in a children's hospital: a prospective descriptive study.
Topics: Adolescent; Anti-Bacterial Agents; Cefepime; Cephalosporins; Child; Child, Preschool; Feasibility Studies; Female; Hospitals, Pediatric; Humans; Infant; Infant, Newborn; Intensive Care Units; Male; Prospective Studies; Standard of Care | 2015 |
Cefepime free minimum concentration to minimum inhibitory concentration (fCmin/MIC) ratio predicts clinical failure in patients with Gram-negative bacterial pneumonia.
Topics: Adult; Aged; Anti-Bacterial Agents; Cefepime; Cephalosporins; Creatinine; Female; Humans; Male; Metabolic Clearance Rate; Microbial Sensitivity Tests; Middle Aged; Plasma; Pneumonia, Bacterial; Retrospective Studies; Treatment Outcome | 2015 |
Compatibility of cefepime and vancomycin during simulated Y-site administration of prolonged infusion.
Topics: Anti-Bacterial Agents; Cefepime; Cephalosporins; Chromatography, High Pressure Liquid; Drug Incompatibility; Drug Stability; Infusions, Intravenous; Infusions, Parenteral; Reference Standards; Vancomycin | 2015 |
Impact of revised cefepime CLSI breakpoints on Escherichia coli and Klebsiella pneumoniae susceptibility and potential impact if applied to Pseudomonas aeruginosa.
Topics: Anti-Bacterial Agents; Cefepime; Cephalosporins; Escherichia coli; Humans; Klebsiella pneumoniae; Microbial Sensitivity Tests; Pseudomonas aeruginosa | 2015 |
X-linked agammaglobulinemia in a child conceived using a donor egg: a medicolegal quandary.
Topics: Access to Information; Agammaglobulinaemia Tyrosine Kinase; Agammaglobulinemia; B-Lymphocytes; Cefepime; Cephalosporins; Child, Preschool; Female; Genetic Diseases, X-Linked; Genetic Testing; Humans; Immunoglobulins, Intravenous; Infections; Male; Mutation; Pregnancy; Protein-Tyrosine Kinases; Tissue Donors; Vancomycin | 2015 |
In vivo activities of simulated human doses of cefepime and cefepime-AAI101 against multidrug-resistant Gram-negative Enterobacteriaceae.
Topics: Animals; beta-Lactamase Inhibitors; Cefepime; Cephalosporins; Enterobacteriaceae; Enterobacteriaceae Infections; Female; Humans; Mice; Microbial Sensitivity Tests | 2015 |
Assay of ceftazidime and cefepime based on fluorescence quenching of carbon quantum dots.
Topics: Carbon; Cefepime; Ceftazidime; Cephalosporins; Fluorescence; Molecular Conformation; Polyethylene Glycols; Quantum Dots; Spectrophotometry, Ultraviolet; Spectroscopy, Fourier Transform Infrared | 2015 |
Cefepime: serious neurological adverse effects.
Topics: Anti-Bacterial Agents; Cefepime; Cephalosporins; Humans; Nervous System; Neurotoxicity Syndromes; Patient Safety; Risk Assessment; Risk Factors | 2015 |
Cefepime-induced jaw myoclonus.
Topics: Anti-Bacterial Agents; Cefepime; Cephalosporins; Humans; Jaw; Myoclonus | 2015 |
Evaluation of clinical outcomes in patients with Gram-negative bloodstream infections according to cefepime MIC.
Topics: Adult; Aged; Aged, 80 and over; Bacteremia; Cefepime; Cephalosporins; Cohort Studies; Female; Gram-Negative Bacteria; Gram-Negative Bacterial Infections; Humans; Length of Stay; Male; Microbial Sensitivity Tests; Middle Aged; Retrospective Studies; Survival Analysis; Treatment Outcome | 2015 |
Cefepime induced acute interstitial nephritis--a case report.
Topics: Acute Kidney Injury; Cefepime; Cephalosporins; Ciprofloxacin; Escherichia coli Infections; Female; Humans; Infusions, Intravenous; Kidney Function Tests; Mastoiditis; Middle Aged; Nephritis, Interstitial; Rare Diseases; Risk Assessment; Treatment Outcome; Withholding Treatment | 2015 |
[Distribution and drug resistance of the pathogenic bacteria from sputum specimens of 1 125 children with tracheo bronchial foreign bodies].
Topics: Bacteria; Cefepime; Cephalosporins; Child; Drug Resistance, Bacterial; Foreign Bodies; Gram-Negative Bacteria; Humans; Meropenem; Microbial Sensitivity Tests; Sputum; Thienamycins | 2015 |
Risk factors for bloodstream infection caused by extended-spectrum β-lactamase-producing Escherichia coli and Klebsiella pneumoniae: A focus on antimicrobials including cefepime.
Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Bacteremia; beta-Lactamases; Case-Control Studies; Cefepime; Cephalosporins; Escherichia coli; Escherichia coli Infections; Female; Hospitals; Humans; Klebsiella Infections; Klebsiella pneumoniae; Male; Michigan; Middle Aged; Retrospective Studies; Risk Factors | 2015 |
Clinical outcomes following hospital-wide implementation of prolonged-infusion cefepime and ceftazidime.
Topics: Adult; Anti-Bacterial Agents; Cefepime; Ceftazidime; Cephalosporins; Gram-Negative Bacterial Infections; Hospitals; Humans; Infusions, Intravenous; Retrospective Studies; Survival Analysis; Time Factors; Treatment Outcome | 2015 |
In vitro bactericidal activity of cefepime and cefpirome against clinical isolates at Karachi.
Topics: Anti-Bacterial Agents; Bacteremia; Cefepime; Cefpirome; Cephalosporins; Drug Resistance, Bacterial; Escherichia coli; Escherichia coli Infections; Humans; In Vitro Techniques; Intraabdominal Infections; Klebsiella Infections; Klebsiella pneumoniae; Microbial Sensitivity Tests; Pakistan; Proteus; Proteus Infections; Respiratory Tract Infections; Skin Diseases, Bacterial; Soft Tissue Infections; Staphylococcal Infections; Staphylococcus aureus; Urinary Tract Infections | 2015 |
Use of aztreonam in association with cefepime for the treatment of nosocomial infections due to multidrug-resistant strains of Pseudomonas aeruginosa to β-lactams in ICU patients: A pilot study.
Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Aztreonam; Bacterial Proteins; beta-Lactam Resistance; beta-Lactamases; Cefepime; Cephalosporins; Critical Care; Cross Infection; Drug Combinations; Drug Resistance, Multiple, Bacterial; Female; Humans; Male; Microbial Sensitivity Tests; Middle Aged; Pilot Projects; Pneumonia, Bacterial; Pseudomonas aeruginosa; Pseudomonas Infections; Retrospective Studies | 2015 |
A green capillary zone electrophoresis method for the simultaneous determination of piperacillin, tazobactam and cefepime in pharmaceutical formulations and human plasma.
Topics: Cefepime; Cephalosporins; Dosage Forms; Electrophoresis, Capillary; Green Chemistry Technology; Humans; Linear Models; Penicillanic Acid; Piperacillin; Reproducibility of Results; Sensitivity and Specificity; Tazobactam | 2015 |
Susceptibility Profile of Ceftolozane/Tazobactam and Other Parenteral Antimicrobials Against Escherichia coli, Klebsiella pneumoniae, and Pseudomonas aeruginosa From US Hospitals.
Topics: Adult; Anti-Infective Agents; beta-Lactamases; Cefepime; Cephalosporins; Cross Infection; Dose-Response Relationship, Drug; Drug Resistance, Bacterial; Enterobacteriaceae; Escherichia coli; Hospitals; Humans; Klebsiella pneumoniae; Microbial Sensitivity Tests; Penicillanic Acid; Piperacillin; Pseudomonas aeruginosa; Tazobactam; United States | 2015 |
The pharmacokinetics change of cefepime after Shuanghuanglian injection administration in subjects with the renal damage.
Topics: Animals; Anti-Bacterial Agents; Area Under Curve; Cefepime; Cephalosporins; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Herb-Drug Interactions; Kidney; Kidney Function Tests; Limit of Detection; Rats, Sprague-Dawley | 2016 |
Sepsis caused by Listeria monocytogenes during chemotherapy for small cell carcinoma of the thymus.
Topics: Aged; Ampicillin; Anti-Bacterial Agents; Antineoplastic Agents; Carboplatin; Carcinoma, Small Cell; Cefepime; Cephalosporins; Etoposide; Female; Granulocyte Colony-Stimulating Factor; Humans; Listeria monocytogenes; Listeriosis; Meropenem; Neoplasm Recurrence, Local; Sepsis; Thienamycins; Thymus Gland; Thymus Neoplasms; Treatment Outcome | 2015 |
Performances from the laboratory to improve the clinical use of cefepime.
Topics: Cefepime; Cephalosporins; Escherichia coli; Klebsiella pneumoniae; Pseudomonas aeruginosa | 2015 |
Trends in Susceptibility Rates and Extended-Spectrum β-Lactamase Production of Klebsiella pneumoniae in Bloodstream Infections Across the United States Veterans Affairs Healthcare System.
Topics: Amikacin; Ampicillin; Anti-Bacterial Agents; Bacteremia; beta-Lactamases; beta-Lactams; Cefepime; Cefoxitin; Ceftazidime; Cephalosporins; Drug Resistance, Multiple, Bacterial; Ertapenem; Fluoroquinolones; Gene Expression Regulation, Bacterial; Humans; Imipenem; Klebsiella Infections; Klebsiella pneumoniae; Microbial Sensitivity Tests; Sulbactam; United States; United States Department of Veterans Affairs | 2015 |
Population pharmacokinetics and dosing simulations of cefepime in septic shock patients receiving continuous renal replacement therapy.
Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Cefepime; Cephalosporins; Female; Humans; Male; Microbial Sensitivity Tests; Middle Aged; Models, Statistical; Plasma; Renal Replacement Therapy; Shock, Septic; Young Adult | 2015 |
Cefepime, a fourth-generation cephalosporin, in complex with manganese, inhibits proteasome activity and induces the apoptosis of human breast cancer cells.
Topics: Apoptosis; Breast Neoplasms; Cefepime; Cell Line, Tumor; Cephalosporins; Copper; Female; Humans; Neoplasm Proteins; Proteasome Endopeptidase Complex; Proteasome Inhibitors | 2015 |
Mutations in β-Lactamase AmpC Increase Resistance of Pseudomonas aeruginosa Isolates to Antipseudomonal Cephalosporins.
Topics: Adaptation, Physiological; Amino Acid Sequence; Amino Acid Substitution; Anti-Bacterial Agents; Aztreonam; Bacterial Proteins; beta-Lactam Resistance; beta-Lactamases; Cefepime; Ceftazidime; Cephalosporins; Gene Expression; Microbial Sensitivity Tests; Molecular Sequence Data; Mutation; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Protein Structure, Secondary; Protein Structure, Tertiary; Pseudomonas aeruginosa; Tazobactam; Ticarcillin | 2015 |
Filtering with Electric Field: The Case of E. coli Porins.
Topics: Anti-Bacterial Agents; Cefepime; Cefotaxime; Cephalosporins; Electricity; Escherichia coli; Molecular Dynamics Simulation; Porins; Protein Structure, Tertiary; Thermodynamics; Water | 2015 |
Reduced Susceptibility to Cefepime in Clinical Isolates of Enterobacteriaceae Producing OXA-1 Beta-Lactamase.
Topics: Anti-Bacterial Agents; beta-Lactamases; Cefepime; Cephalosporins; DNA, Bacterial; Drug Resistance, Multiple, Bacterial; Electrophoresis, Gel, Pulsed-Field; Enterobacteriaceae; Enterobacteriaceae Infections; Gene Expression; Humans; Isoenzymes; Microbial Sensitivity Tests; Molecular Epidemiology; Multilocus Sequence Typing; Plasmids; Sequence Analysis, DNA; Spain | 2016 |
Cefepime and Ceftazidime Safety in Hospitalized Infants.
Topics: Anti-Bacterial Agents; Cefepime; Ceftazidime; Cephalosporins; Drug-Related Side Effects and Adverse Reactions; Gram-Negative Bacterial Infections; Hospitalization; Humans; Infant; Infant, Newborn; Seizures; Survival Analysis | 2015 |
In Vivo Evolution of CMY-2 to CMY-33 β-Lactamase in Escherichia coli Sequence Type 131: Characterization of an Acquired Extended-Spectrum AmpC Conferring Resistance to Cefepime.
Topics: Aged; Anti-Bacterial Agents; Bacterial Proteins; beta-Lactamases; Carbapenems; Cefepime; Ceftriaxone; Cephalosporins; Drug Resistance, Multiple, Bacterial; Escherichia coli; Escherichia coli Infections; Escherichia coli Proteins; Humans; Male; Microbial Sensitivity Tests; Molecular Docking Simulation | 2015 |
Phototoxicity, Pseudoporphyria, and Photo-onycholysis Due to Voriconazole in a Pediatric Patient With Leukemia and Invasive Aspergillosis.
Topics: Ankle; Aspergillosis; Blister; Catheter-Related Infections; Cefepime; Cephalosporins; Cheilitis; Child; Cicatrix; Clindamycin; Dermatitis, Phototoxic; Echinocandins; Humans; Hypokalemia; Immunocompromised Host; Levofloxacin; Lipopeptides; Magnesium Deficiency; Male; Micafungin; Onycholysis; Photosensitivity Disorders; Porphyrias; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Vancomycin; Voriconazole | 2015 |
Cefepime Therapy for Monomicrobial Enterobacter cloacae Bacteremia: Unfavorable Outcomes in Patients Infected by Cefepime-Susceptible Dose-Dependent Isolates.
Topics: Aged; Anti-Bacterial Agents; Bacteremia; beta-Lactam Resistance; beta-Lactamases; Carbapenems; Cefepime; Cephalosporins; Diabetes Complications; Diabetes Mellitus; Enterobacter cloacae; Enterobacteriaceae Infections; Female; Gene Expression; Humans; Male; Microbial Sensitivity Tests; Middle Aged; Multivariate Analysis; Neoplasms; Renal Insufficiency, Chronic; Retrospective Studies; Severity of Illness Index; Survival Analysis; Treatment Outcome | 2015 |
Efficacy of humanized high-dose meropenem, cefepime, and levofloxacin against Enterobacteriaceae isolates producing Verona integron-encoded metallo-β-lactamase (VIM) in a murine thigh infection model.
Topics: Animals; Anti-Infective Agents; Bacterial Proteins; beta-Lactamases; Cefepime; Cephalosporins; Enterobacteriaceae; Enterobacteriaceae Infections; Levofloxacin; Meropenem; Mice; Microbial Sensitivity Tests; Thienamycins; Thigh | 2015 |
Effect of ceftriaxone and cefepime on high-dose methotrexate clearance.
Topics: Administration, Intravenous; Animals; Anti-Bacterial Agents; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Cefepime; Ceftriaxone; Cephalosporins; Drug Interactions; Humans; Kidney Tubules, Proximal; Male; Methotrexate; Young Adult | 2016 |
Phylogenetic group distributions, virulence factors and antimicrobial resistance properties of uropathogenic Escherichia coli strains isolated from patients with urinary tract infections in South Korea.
Topics: Anti-Bacterial Agents; Cefepime; Cefoxitin; Ceftazidime; Cephalosporins; Child; Chloramphenicol; Drug Resistance, Multiple, Bacterial; Escherichia coli Infections; Escherichia coli Proteins; Humans; Microbial Sensitivity Tests; Phylogeny; Republic of Korea; Urinary Tract Infections; Uropathogenic Escherichia coli; Virulence Factors | 2016 |
Interactions of OP0595, a Novel Triple-Action Diazabicyclooctane, with β-Lactams against OP0595-Resistant Enterobacteriaceae Mutants.
Topics: Anti-Bacterial Agents; Azabicyclo Compounds; Aztreonam; beta-Lactam Resistance; beta-Lactamases; Cefepime; Cephalosporins; Drug Combinations; Drug Synergism; Enterobacteriaceae; Escherichia coli Proteins; Gene Expression; Lactams; Meropenem; Microbial Sensitivity Tests; Mutation; Penicillin-Binding Proteins; Piperacillin; Plasmids; Protein Isoforms; Thienamycins | 2016 |
In vitro activity of cefepime against extended spectrum p-lactamase-producing Escherichia coli and Klebsiella pneumoniae from clinical specimens at Bugando Medical Centre, Mwanza, Tanzania.
Topics: Anti-Bacterial Agents; beta-Lactamases; Cefepime; Cephalosporins; Escherichia coli; Humans; In Vitro Techniques; Klebsiella pneumoniae; Microbial Sensitivity Tests; Tanzania | 2011 |
Investigation of a cluster of Clostridium difficile infections in a pediatric oncology setting.
Topics: Adolescent; Anti-Bacterial Agents; Case-Control Studies; Cefepime; Cephalosporins; Child; Child, Preschool; Clostridioides difficile; Clostridium Infections; Cross Infection; Feces; Female; Hospitalization; Hospitals; Humans; Infant; Infection Control; Male; Medical Oncology; Pediatrics; Risk Factors; Young Adult | 2016 |
Silver- and fluoride-containing mesoporous bioactive glasses versus commonly used antibiotics: Activity against multidrug-resistant bacterial strains isolated from patients with burns.
Topics: Amikacin; Animals; Anti-Bacterial Agents; Aztreonam; Burns; Carbenicillin; Cefepime; Ceftazidime; Ceftriaxone; Cell Survival; Cephalosporins; Ciprofloxacin; Drug Resistance, Multiple, Bacterial; Fluorides; Gentamicins; Glass; Humans; Imipenem; Meropenem; Mice; Microbial Sensitivity Tests; NIH 3T3 Cells; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Pseudomonas aeruginosa; Silver; Thienamycins; Tobramycin; Wound Infection | 2016 |
Defining Clinical Exposures of Cefepime for Gram-Negative Bloodstream Infections That Are Associated with Improved Survival.
Topics: Adult; Aged; Anti-Bacterial Agents; APACHE; Cefepime; Cephalosporins; Cohort Studies; Female; Gram-Negative Bacteria; Gram-Negative Bacterial Infections; Humans; Illinois; Intensive Care Units; Length of Stay; Male; Microbial Sensitivity Tests; Middle Aged; Models, Theoretical; Multivariate Analysis; Patient Readmission; Retrospective Studies; Treatment Outcome | 2015 |
[Analysis of pathogen spectrum and resistance of clinical common organisms causing bloodstream infections, hospital-acquired pneumonia and intra-abdominal infections from thirteen teaching hospitals in 2013].
Topics: Anti-Bacterial Agents; Bacteremia; Carbapenems; Cefepime; Cephalosporins; China; Cross Infection; Hospitals, Teaching; Humans; Intraabdominal Infections; Microbial Sensitivity Tests; Minocycline; Pneumonia; Tigecycline; Vancomycin | 2015 |
An exploratory analysis of the ability of a cefepime trough concentration greater than 22 mg/L to predict neurotoxicity.
Topics: Adult; Anti-Bacterial Agents; Bayes Theorem; Cefepime; Cephalosporins; Humans; Kidney; Neurotoxicity Syndromes | 2016 |
[Distribution of pathogens in diabetic foot osteomyelitis and risk factors of osteomyelitis].
Topics: Anti-Bacterial Agents; Cefepime; Cephalosporins; Diabetic Foot; Drug Resistance, Multiple, Bacterial; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; Osteomyelitis; Risk Factors; Wound Infection | 2015 |
Study of Common Bacterial and Fungal Pathogens in Children with Hematological Malignancies during Febrile Neutropenia: Single Center Egyptian Study.
Topics: Adolescent; Ampicillin; Anti-Bacterial Agents; Antifungal Agents; Bacteremia; Blood Cell Count; Candida; Cefepime; Cephalosporins; Child; Child, Preschool; Egypt; Febrile Neutropenia; Female; Fungi; Gram-Negative Bacteria; Hematologic Neoplasms; Humans; Male; Pharynx; Pseudomonas aeruginosa; Staphylococcus aureus | 2016 |
[Antimicrobial susceptibility of community-acquired respiratory tract pathogens isolated from class B hospitals in China during 2013 and 2014].
Topics: Anti-Bacterial Agents; Aza Compounds; Cefepime; Cephalosporins; China; Clarithromycin; Community-Acquired Infections; Drug Resistance, Bacterial; Fluoroquinolones; Haemophilus influenzae; Humans; Klebsiella pneumoniae; Levofloxacin; Macrolides; Microbial Sensitivity Tests; Moraxella catarrhalis; Moxifloxacin; Penicillins; Respiratory Tract Infections; Staphylococcus aureus; Streptococcus pneumoniae | 2016 |
Population Pharmacokinetic Assessment and Pharmacodynamic Implications of Pediatric Cefepime Dosing for Susceptible-Dose-Dependent Organisms.
Topics: Anti-Bacterial Agents; Cefepime; Cephalosporins; Computer Simulation; Creatinine; Drug Dosage Calculations; Enterobacteriaceae; Enterobacteriaceae Infections; Female; Humans; Infant; Infant, Newborn; Infusions, Intravenous; Male; Microbial Sensitivity Tests; Models, Statistical; Monte Carlo Method; Pseudomonas aeruginosa; Pseudomonas Infections | 2016 |
Epidemiological and clinical features for cefepime heteroresistant Escherichia coli infections in Southwest China.
Topics: Adult; Aged; Anti-Bacterial Agents; beta-Lactam Resistance; Bile; Blood; Case-Control Studies; Cefepime; Cephalosporins; China; Drainage; Electrophoresis, Gel, Pulsed-Field; Escherichia coli; Escherichia coli Infections; Female; Genetic Variation; Hospitals, Teaching; Humans; Male; Middle Aged; Molecular Typing; Retrospective Studies; Risk Factors | 2016 |
Three-times-weekly, post-dialysis cefepime therapy in patients on maintenance hemodialysis: a retrospective study.
Topics: Aged; Anti-Bacterial Agents; Anuria; Cefepime; Cephalosporins; Cohort Studies; Drug Administration Schedule; Drug Monitoring; Female; Gram-Negative Bacteria; Gram-Negative Bacterial Infections; Humans; Infusions, Intravenous; Male; Microbial Sensitivity Tests; Middle Aged; Outpatient Clinics, Hospital; Renal Dialysis; Renal Elimination; Renal Insufficiency, Chronic; Retrospective Studies; Staphylococcal Infections; Staphylococcus aureus | 2016 |
Bioactive ZnO Coatings Deposited by MAPLE-An Appropriate Strategy to Produce Efficient Anti-Biofilm Surfaces.
Topics: Animals; Anti-Bacterial Agents; Biofilms; Cefepime; Cephalosporins; Coated Materials, Biocompatible; Cyclodextrins; Mice; Nanostructures; X-Ray Diffraction; Zinc Oxide | 2016 |
A rapid and sensitive colorimetric measurement of antibiotic efficacy against Escherichia coli in vitro.
Topics: Anti-Bacterial Agents; beta-Lactamases; Cefepime; Cephalosporins; Colorimetry; Drug Resistance, Bacterial; Escherichia coli; Ferricyanides; Ferrocyanides; Gentamicins; Microbial Sensitivity Tests | 2016 |
Tissue penetration and exposure of cefepime in patients with diabetic foot infections.
Topics: Cefepime; Cephalosporins; Diabetes Mellitus; Foot Diseases; Humans; Pseudomonas aeruginosa; Pseudomonas Infections | 2016 |
Antibiotic Resistance Patterns of Gram-Negative Psychrotrophic Bacteria from Bulk Tank Milk.
Topics: Animals; Anti-Bacterial Agents; Cefepime; Cephalosporins; Drug Resistance, Microbial; Enterobacteriaceae; Food Microbiology; Gram-Negative Bacteria; Humans; Imipenem; Meropenem; Microbial Sensitivity Tests; Milk; Pseudomonadaceae; Thienamycins | 2016 |
Prospective Comparison of Acute Kidney Injury During Treatment With the Combination of Piperacillin-Tazobactam and Vancomycin Versus the Combination of Cefepime or Meropenem and Vancomycin.
Topics: Acute Kidney Injury; Aged; Aged, 80 and over; Anti-Bacterial Agents; Cefepime; Cephalosporins; Cohort Studies; Drug Therapy, Combination; Female; Humans; Male; Meropenem; Middle Aged; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Prospective Studies; Thienamycins; Treatment Outcome; Vancomycin | 2017 |
Ampicillin in Combination with Ceftaroline, Cefepime, or Ceftriaxone Demonstrates Equivalent Activities in a High-Inoculum Enterococcus faecalis Infection Model.
Topics: Ampicillin; Anti-Bacterial Agents; Cefepime; Ceftaroline; Ceftriaxone; Cephalosporins; Enterococcus faecalis; Gentamicins; Microbial Sensitivity Tests | 2016 |
The antibiotic cefepime interferes with amino acid analysis by ion-exchange chromatography.
Topics: Adolescent; Adult; Amino Acids; Anti-Bacterial Agents; Artifacts; Blood Chemical Analysis; Cefepime; Cephalosporins; Chromatography, Ion Exchange; Female; Humans; Middle Aged | 2016 |
Comparative Incidence of Acute Kidney Injury in Critically Ill Patients Receiving Vancomycin with Concomitant Piperacillin-Tazobactam or Cefepime: A Retrospective Cohort Study.
Topics: Acute Kidney Injury; Anti-Bacterial Agents; Arkansas; Cefepime; Cephalosporins; Critical Illness; Drug Therapy, Combination; Female; Humans; Incidence; Male; Middle Aged; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Retrospective Studies; Vancomycin | 2016 |
In Vitro and In Vivo Activities of OP0595, a New Diazabicyclooctane, against CTX-M-15-Positive Escherichia coli and KPC-Positive Klebsiella pneumoniae.
Topics: Azabicyclo Compounds; beta-Lactamases; Cefepime; Cephalosporins; Escherichia coli; Klebsiella pneumoniae; Lactams; Meropenem; Microbial Sensitivity Tests; Piperacillin; Thienamycins | 2016 |
Disseminated Histoplasmosis with Skin Lesions and Osteomyelitis in a Patient from the Philippines.
Topics: Administration, Intravenous; Administration, Oral; Aged; Amphotericin B; Cefepime; Cephalosporins; Dexamethasone; Follow-Up Studies; Histoplasma; Histoplasmosis; Humans; Immunocompromised Host; Magnetic Resonance Imaging; Male; Osteomyelitis; Philippines; Skin Diseases; Thalidomide; Vancomycin | 2016 |
Cefepime shows good efficacy and no antibiotic resistance in pneumonia caused by Serratia marcescens and Proteus mirabilis - an observational study.
Topics: Aged; Anti-Bacterial Agents; Bronchoalveolar Lavage Fluid; Cefepime; Cephalosporins; Disk Diffusion Antimicrobial Tests; Drug Resistance, Multiple, Bacterial; Female; Germany; Hospital Mortality; Hospitals, University; Humans; Kaplan-Meier Estimate; Length of Stay; Male; Middle Aged; Pneumonia, Bacterial; Proteus Infections; Proteus mirabilis; Retrospective Studies; Serratia Infections; Serratia marcescens | 2016 |
Impact of Cefepime Susceptible-Dose-Dependent MIC for Enterobacteriaceae on Reporting and Prescribing.
Topics: Anti-Bacterial Agents; Carbapenems; Cefepime; Cephalosporins; Drug Prescriptions; Enterobacteriaceae; Enterobacteriaceae Infections; Humans; Microbial Sensitivity Tests | 2016 |
What does the susceptible-dose dependent interpretive category for cefepime in ESBL-producing bacteria?
Topics: Anti-Bacterial Agents; Bacterial Proteins; beta-Lactamases; Brazil; Cefepime; Cephalosporins; Drug Resistance, Bacterial; Drug Resistance, Multiple, Bacterial; Enterobacter cloacae; Enterobacteriaceae Infections; Genes, Bacterial; Humans; Inactivation, Metabolic; Intensive Care Units; Klebsiella Infections; Klebsiella pneumoniae; Microbial Sensitivity Tests; Molecular Typing; Practice Guidelines as Topic | 2017 |
In Vivo and In Vitro Efficacy of Minocycline-Based Combination Therapy for Minocycline-Resistant Acinetobacter baumannii.
Topics: Acinetobacter baumannii; Acinetobacter Infections; Animals; Anti-Bacterial Agents; Biofilms; Cefepime; Cephalosporins; Colistin; Drug Resistance, Multiple, Bacterial; Gentamicins; Imipenem; Meropenem; Mice; Microbial Sensitivity Tests; Minocycline; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Pneumonia; Taiwan; Thienamycins | 2016 |
Therapeutic drug monitoring of cefepime with micellar electrokinetic capillary chromatography: Assay improvement, quality assurance, and impact on patient drug levels.
Topics: Cefepime; Cephalosporins; Chromatography, Micellar Electrokinetic Capillary; Drug Monitoring; Humans; Molecular Structure; Quality Improvement | 2016 |
Previous Antibiotic Exposure Increases Risk of Infection with Extended-Spectrum-β-Lactamase- and AmpC-Producing Escherichia coli and Klebsiella pneumoniae in Pediatric Patients.
Topics: Adolescent; Adult; Anti-Bacterial Agents; Aztreonam; Bacterial Proteins; beta-Lactamases; Cefepime; Cefotaxime; Ceftazidime; Ceftriaxone; Cephalosporins; Child; Child, Preschool; Drug Resistance, Multiple, Bacterial; Escherichia coli; Escherichia coli Infections; Female; Humans; Infant; Infant, Newborn; Klebsiella Infections; Klebsiella pneumoniae; Male; Microbial Sensitivity Tests; Prospective Studies; Young Adult | 2016 |
[Drug tolerance and PFGE molecular typing of Salmonella paratyphi A isolated in Dengfeng, Henan province, 2009-2015].
Topics: Agglutination Tests; Anti-Bacterial Agents; Cefepime; Cephalosporins; China; Drug Resistance, Bacterial; Drug Tolerance; Electrophoresis, Gel, Pulsed-Field; Humans; Molecular Typing; Paratyphoid Fever; Salmonella paratyphi A; Tetracycline | 2016 |
Differential Antimicrobial Susceptibilities of Granulicatella adiacens and Abiotrophia defectiva.
Topics: Abiotrophia; Anti-Infective Agents; Carnobacteriaceae; Cefepime; Cefotaxime; Cephalosporins; Clindamycin; Erythromycin; Levofloxacin; Microbial Sensitivity Tests; Penicillins; Vancomycin | 2016 |
Simultaneous Determination of Eight β-Lactam Antibiotics, Amoxicillin, Cefazolin, Cefepime, Cefotaxime, Ceftazidime, Cloxacillin, Oxacillin, and Piperacillin, in Human Plasma by Using Ultra-High-Performance Liquid Chromatography with Ultraviolet Detection
Topics: Amoxicillin; Anti-Bacterial Agents; beta-Lactams; Cefazolin; Cefepime; Cefotaxime; Ceftazidime; Cephalosporins; Chromatography, High Pressure Liquid; Cloxacillin; Drug Monitoring; Humans; Oxacillin; Piperacillin; Ultraviolet Rays | 2016 |
Impact of computerized pre-authorization of broad spectrum antibiotics in Pseudomonas aeruginosa at a children's hospital in Japan.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Carbapenems; Cefepime; Ceftazidime; Cephalosporins; Hospitals; Humans; Japan; Microbial Sensitivity Tests; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Pseudomonas aeruginosa; Pseudomonas Infections; Tokyo | 2016 |
Use of Intravenous Vancomycin and Cefepime in Preventing Endophthalmitis After Open Globe Injury.
Topics: Administration, Intravenous; Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Cefepime; Cephalosporins; Child; Child, Preschool; Endophthalmitis; Eye Infections, Bacterial; Eye Injuries, Penetrating; Female; Humans; Infant; Male; Middle Aged; Retrospective Studies; Vancomycin; Young Adult | 2016 |
Pharmacokinetics of Cefepime in Patients with Cancer and Febrile Neutropenia in the Setting of Hematologic Malignancies or Hematopoeitic Cell Transplantation.
Topics: Adult; Aged; Anti-Bacterial Agents; Cefepime; Cephalosporins; Febrile Neutropenia; Female; Hematologic Neoplasms; Hematopoietic Stem Cell Transplantation; Humans; Male; Microbial Sensitivity Tests; Middle Aged; Models, Biological; Prospective Studies | 2016 |
Crystal structure of EstSRT1, a family VIII carboxylesterase displaying hydrolytic activity toward oxyimino cephalosporins.
Topics: Amino Acid Sequence; Anti-Bacterial Agents; Bacterial Proteins; Carboxylic Ester Hydrolases; Catalytic Domain; Cefepime; Cefotaxime; Cephalosporins; Cloning, Molecular; Crystallography, X-Ray; Escherichia coli; Gene Expression; Hydrolysis; Isoenzymes; Models, Molecular; Protein Interaction Domains and Motifs; Protein Structure, Secondary; Recombinant Proteins; Sequence Alignment; Structural Homology, Protein | 2016 |
Involvement of the Multidrug Efflux Pumps in Betalactams Resistant Pseudomonas aerugionsa Clinical Isolates Collected from Burn Patients in Iran.
Topics: Bacterial Outer Membrane Proteins; beta-Lactam Resistance; beta-Lactamases; Burns; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Cefepime; Cephalosporins; Drug Resistance, Multiple, Bacterial; Genes, MDR; Humans; Imipenem; Iran; Membrane Transport Proteins; Microbial Sensitivity Tests; Phenotype; Polymerase Chain Reaction; Pseudomonas aeruginosa; Pseudomonas Infections | 2016 |
[Study on drug sensitivity against Comamonas testosteroni by Kirby-Bauer disk diffusion method].
Topics: Anti-Bacterial Agents; Cefepime; Cephalosporins; Comamonas testosteroni; Imipenem; Meropenem; Microbial Sensitivity Tests; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Pseudomonas aeruginosa; Thienamycins | 2016 |
Antimicrobial-resistant Pseudomonas aeruginosa and Acinetobacter baumannii From Patients With Hospital-acquired or Ventilator-associated Pneumonia in Vietnam.
Topics: Acinetobacter baumannii; Amikacin; Anti-Bacterial Agents; beta-Lactamase Inhibitors; beta-Lactams; Carbapenems; Cefepime; Cephalosporins; Cross Infection; Doripenem; Drug Resistance, Multiple, Bacterial; Fluoroquinolones; Gentamicins; Humans; Longitudinal Studies; Microbial Sensitivity Tests; Minocycline; Pneumonia, Bacterial; Pneumonia, Ventilator-Associated; Pseudomonas aeruginosa; Tigecycline; Vietnam | 2016 |
Cefepime loaded O-carboxymethyl chitosan microspheres with sustained bactericidal activity and enhanced biocompatibility.
Topics: Anti-Bacterial Agents; Cefepime; Cell Line; Cephalosporins; Chitosan; Delayed-Action Preparations; Drug Carriers; Drug Liberation; Humans; Materials Testing; Microbial Sensitivity Tests; Microspheres | 2017 |
Nephrotoxicity during Vancomycin Therapy in Combination with Piperacillin-Tazobactam or Cefepime.
Topics: Acute Kidney Injury; Adult; Aged; Anti-Bacterial Agents; Cefepime; Cephalosporins; Female; Humans; Kidney; Male; Middle Aged; Multivariate Analysis; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Retrospective Studies; Vancomycin | 2017 |
Improved Accuracy of Cefepime Susceptibility Testing for Extended-Spectrum-Beta-Lactamase-Producing Enterobacteriaceae with an On-Demand Digital Dispensing Method.
Topics: Anti-Bacterial Agents; beta-Lactamases; Cefepime; Cephalosporins; Enterobacteriaceae; Humans; Microbial Sensitivity Tests; Reproducibility of Results | 2017 |
Relationship between PK/PD of Cefepime and Clinical Outcome in Febrile Neutropenic Patients with Normal Renal Function.
Topics: Adult; Aged; Anti-Bacterial Agents; Cefepime; Cephalosporins; Creatinine; Dose-Response Relationship, Drug; Febrile Neutropenia; Female; Glomerular Filtration Rate; Humans; Kidney; Male; Metabolic Clearance Rate; Middle Aged; Treatment Outcome | 2016 |
Risk of Acute Kidney Injury in Patients on Concomitant Vancomycin and Piperacillin-Tazobactam Compared to Those on Vancomycin and Cefepime.
Topics: Acute Kidney Injury; Adult; Aged; Anti-Bacterial Agents; Cefepime; Cephalosporins; Combined Modality Therapy; Drug Therapy, Combination; Female; Humans; Length of Stay; Male; Middle Aged; Odds Ratio; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Prognosis; Retrospective Studies; Risk; Severity of Illness Index; Vancomycin | 2017 |
Aspergillus Terreus Brain Abscess Complicated by Tension Pneumocephalus in a Patient with Angiosarcoma.
Topics: Aged; Anti-Bacterial Agents; Aspergillosis; Aspergillus; Bacteremia; Brain Abscess; Cefepime; Cephalosporins; Disease Progression; Drug Combinations; Drug Therapy, Combination; Glucocorticoids; Hemangiosarcoma; Humans; Immunocompromised Host; Magnetic Resonance Imaging; Male; Pneumocephalus; Proteus mirabilis; Skin Neoplasms; Staphylococcus aureus; Sulfamethizole; Tomography, X-Ray Computed; Treatment Outcome; Trimethoprim; Vancomycin; Voriconazole | 2017 |
A propensity score-matched analysis of the impact of minimum inhibitory concentration on mortality in patients with Pseudomonas aeruginosa bacteremia treated with cefepime or ceftazidime.
Topics: Aged; Anti-Bacterial Agents; Bacteremia; Cefepime; Ceftazidime; Cephalosporins; Female; Humans; Male; Microbial Sensitivity Tests; Multivariate Analysis; Propensity Score; Pseudomonas aeruginosa; Pseudomonas Infections | 2017 |
Development of an algorithm for phenotypic screening of carbapenemase-producing Enterobacteriaceae in the routine laboratory.
Topics: Algorithms; Anti-Bacterial Agents; Bacterial Proteins; beta-Lactamases; beta-Lactams; Carbapenems; Cefepime; Cephalosporins; Clavulanic Acids; Drug Resistance, Bacterial; Enterobacteriaceae; Ertapenem; Humans; Imipenem; Meropenem; Microbial Sensitivity Tests; Penicillanic Acid; Penicillins; Tazobactam; Thienamycins; Ticarcillin | 2017 |
Cefepime plasma concentrations and clinical toxicity: a retrospective cohort study.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Cefepime; Cephalosporins; Chromatography, High Pressure Liquid; Drug Monitoring; Female; Humans; Infusions, Intravenous; Male; Middle Aged; Nervous System Diseases; Plasma; Retrospective Studies; Young Adult | 2017 |
Determining β-lactam exposure threshold to suppress resistance development in Gram-negative bacteria.
Topics: Anti-Bacterial Agents; beta-Lactam Resistance; beta-Lactams; Cefepime; Ceftazidime; Cephalosporins; Humans; Kinetics; Klebsiella pneumoniae; Meropenem; Microbial Sensitivity Tests; Pseudomonas aeruginosa; Tandem Mass Spectrometry; Thienamycins | 2017 |
Antibiotic stability related to temperature variations in elastomeric pumps used for outpatient parenteral antimicrobial therapy (OPAT).
Topics: Anti-Bacterial Agents; Cefazolin; Cefepime; Cephalosporins; Drug Stability; Elastomers; Female; Floxacillin; Healthy Volunteers; Humans; Infusion Pumps; Male; Piperacillin; Polymers; Temperature | 2017 |
In vitro activity of cefepime/zidebactam (WCK 5222) against Gram-negative bacteria.
Topics: Anti-Bacterial Agents; Azabicyclo Compounds; beta-Lactamase Inhibitors; Cefepime; Cephalosporins; Citrobacter; Cyclooctanes; Enterobacteriaceae; Enterobacteriaceae Infections; Escherichia coli; Gram-Negative Bacteria; Humans; Klebsiella; Microbial Sensitivity Tests; Piperidines | 2017 |
Monitoring of cefepime in human serum and plasma by micellar electrokinetic capillary chromatography: Improvement of sample preparation and validation by liquid chromatography coupled to mass spectrometry.
Topics: Cefepime; Cephalosporins; Chromatography, Liquid; Chromatography, Micellar Electrokinetic Capillary; Humans; Mass Spectrometry | 2017 |
First case of pneumonia caused by Cupriavidus pauculus in an infant in the Gulf Cooperation Council.
Topics: Anti-Bacterial Agents; Cefepime; Cephalosporins; Cupriavidus; Gram-Negative Bacterial Infections; Humans; Infant; Kidney Failure, Chronic; Male; Microbial Sensitivity Tests; Pneumonia, Bacterial; Saudi Arabia | 2017 |
Ceftriaxone Etest non-susceptible methicillin susceptible Staphylococcus aureus time-kill responses.
Topics: Anti-Bacterial Agents; Bacteremia; Cefepime; Ceftaroline; Ceftriaxone; Cefuroxime; Cephalosporins; Cephalothin; Disk Diffusion Antimicrobial Tests; Humans; Oxacillin; Staphylococcus aureus | 2017 |
Retrospective survey and evaluation of first-line antibiotics for chemotherapy-induced febrile neutropenia in patients with acute myeloid leukemia.
Topics: Adult; Aged; Amikacin; Anti-Bacterial Agents; Antifungal Agents; Cefepime; Cefozopran; Cephalosporins; Chemotherapy-Induced Febrile Neutropenia; Female; Humans; Male; Middle Aged; Piperacillin; Retrospective Studies | 2017 |
Trends in Drug Resistance of
Topics: Acinetobacter baumannii; Amikacin; Anti-Infective Agents; Cefepime; Cefoperazone; Ceftazidime; Cephalosporins; China; Colistin; Drug Resistance, Multiple, Bacterial; Humans; Imipenem; Levofloxacin; Microbial Sensitivity Tests; Minocycline; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Sulbactam | 2017 |
Antimicrobial salvage therapy for native valve MRSA endocarditis.
Topics: Adult; Anti-Bacterial Agents; Bacteremia; Cefepime; Cephalosporins; Daptomycin; Endocarditis, Bacterial; Humans; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Middle Aged; Staphylococcal Infections; Vancomycin | 2017 |
WCK 5222 (cefepime/zidebactam) antimicrobial activity tested against Gram-negative organisms producing clinically relevant β-lactamases.
Topics: Acinetobacter baumannii; Acinetobacter Infections; Anti-Bacterial Agents; Azabicyclo Compounds; beta-Lactamase Inhibitors; beta-Lactamases; Cefepime; Cephalosporins; Cyclooctanes; Drug Synergism; Enterobacteriaceae; Enterobacteriaceae Infections; Humans; Microbial Sensitivity Tests; Piperidines; Pseudomonas aeruginosa; Pseudomonas Infections | 2017 |
Activity of cefiderocol (S-649266) against carbapenem-resistant Gram-negative bacteria collected from inpatients in Greek hospitals.
Topics: Acinetobacter baumannii; Anti-Bacterial Agents; Bacterial Proteins; beta-Lactam Resistance; beta-Lactamases; Carbapenems; Cefepime; Cefiderocol; Ceftazidime; Cephalosporins; Colistin; Drug Resistance, Multiple, Bacterial; Gram-Negative Bacteria; Gram-Negative Bacterial Infections; Greece; Humans; Inpatients; Klebsiella pneumoniae; Meropenem; Microbial Sensitivity Tests; Minocycline; Pseudomonas aeruginosa; Thienamycins; Tigecycline | 2017 |
Antimicrobial-resistant infections among postpartum women at a Ugandan referral hospital.
Topics: Acinetobacter; Acinetobacter Infections; Adolescent; Adult; Cefepime; Cephalosporins; Drug Resistance, Multiple, Bacterial; Female; Humans; Postpartum Period; Pregnancy; Pregnancy Complications, Infectious; Prospective Studies; Uganda | 2017 |
Cefepime-induced encephalopathy in end-stage renal disease patients.
Topics: Aged; Anti-Bacterial Agents; Brain Diseases; Cefepime; Cephalosporins; Comorbidity; Dose-Response Relationship, Drug; Female; Humans; Incidence; Kidney Failure, Chronic; Male; Middle Aged; Retrospective Studies; Risk Factors | 2017 |
Piperacillin-tazobactam versus cefepime incidence of acute kidney injury in combination with vancomycin and tobramycin in pediatric cystic fibrosis patients.
Topics: Acute Kidney Injury; Adolescent; Anti-Bacterial Agents; Cefepime; Cephalosporins; Child; Cystic Fibrosis; Drug Therapy, Combination; Female; Hospitalization; Humans; Incidence; Male; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Retrospective Studies; Tobramycin; Vancomycin | 2017 |
Analytical interference during cefepime therapeutic drug monitoring in intensive care patient: About a case report.
Topics: Anti-Bacterial Agents; Cefepime; Cephalosporins; Chromatography, High Pressure Liquid; Drug Monitoring; Humans; Intensive Care Units; Male; Middle Aged | 2017 |
Acute kidney injury risk associated with piperacillin/tazobactam compared with cefepime during vancomycin therapy in hospitalised patients: a cohort study stratified by baseline kidney function.
Topics: Acute Kidney Injury; Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; beta-Lactamase Inhibitors; Cefepime; Cephalosporins; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Retrospective Studies; Risk Assessment; Vancomycin; Young Adult | 2017 |
In vitro susceptibility and resistance phenotypes in contemporary Enterobacter isolates in a university hospital in Crete, Greece.
Topics: Aminoglycosides; Anti-Bacterial Agents; Bacterial Proteins; beta-Lactamases; beta-Lactams; Carbapenems; Cefepime; Cephalosporins; Child; Colistin; Drug Resistance, Multiple, Bacterial; Enterobacter; Enterobacteriaceae Infections; Greece; Hospitals, University; Humans; Microbial Sensitivity Tests; Minocycline; Penicillanic Acid; Phenotype; Piperacillin; Piperacillin, Tazobactam Drug Combination; Tigecycline | 2017 |
Characterizing non-linear effects of hospitalisation duration on antimicrobial resistance in respiratory isolates: an analysis of a prospective nationwide surveillance system.
Topics: Amoxicillin-Potassium Clavulanate Combination; Anti-Bacterial Agents; Cefepime; Cephalosporins; Cross Infection; Drug Resistance, Bacterial; Enterobacter; Escherichia coli; Female; Hospitalization; Humans; Klebsiella pneumoniae; Length of Stay; Male; Microbial Sensitivity Tests; Middle Aged; Oxacillin; Pneumonia; Pseudomonas aeruginosa; Respiratory System; Retrospective Studies; Staphylococcus aureus; Streptococcus pneumoniae | 2018 |
Defining the impact of severity of illness on time above the MIC threshold for cefepime in Gram-negative bacteraemia: a 'Goldilocks' window.
Topics: Adult; Aged; Anti-Bacterial Agents; Bacteremia; Cefepime; Cephalosporins; Female; Humans; Male; Microbial Sensitivity Tests; Middle Aged; Retrospective Studies; Serum; Severity of Illness Index; Survival Analysis; Time Factors; Treatment Outcome | 2017 |
Enhanced antimicrobial de-escalation for pneumonia in mechanically ventilated patients: a cross-over study.
Topics: Academic Medical Centers; Aged; Anti-Bacterial Agents; Carbapenems; Cefepime; Ceftriaxone; Cephalosporins; Cross-Over Studies; Female; Hospital Mortality; Humans; Intensive Care Units; Male; Middle Aged; Monobactams; Pneumonia; Pneumonia, Ventilator-Associated; Prospective Studies; Quinolones; Respiration, Artificial; Statistics, Nonparametric | 2017 |
Influence of β-Lactam Infusion Strategy on Acute Kidney Injury.
Topics: Acute Kidney Injury; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; beta-Lactamase Inhibitors; Cefepime; Cephalosporins; Drug Therapy, Combination; Female; Humans; Kidney; Male; Meropenem; Middle Aged; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Retrospective Studies; Thienamycins | 2017 |
Acute interstitial nephritis and DRESS syndrome without eosinophilia associated with cefepime.
Topics: Acute Disease; Anti-Bacterial Agents; Cefepime; Cephalosporins; Diagnosis, Differential; Drug Hypersensitivity Syndrome; Glucocorticoids; Humans; Male; Middle Aged; Nephritis, Interstitial; Prednisone | 2017 |
Determination of Disk Diffusion and MIC Quality Control Guidelines for High-Dose Cefepime-Tazobactam (WCK 4282), a Novel Antibacterial Combination Consisting of a β-Lactamase Inhibitor and a Fourth-Generation Cephalosporin.
Topics: Anti-Bacterial Agents; beta-Lactamase Inhibitors; beta-Lactamases; Cefepime; Cephalosporins; Disk Diffusion Antimicrobial Tests; Drug Combinations; Gram-Negative Bacteria; Gram-Negative Bacterial Infections; Guidelines as Topic; Humans; Penicillanic Acid; Quality Control; Tazobactam | 2017 |
Does compliance with antibiotic prophylaxis in pediatric simple appendicitis matter?
Topics: Adolescent; Anti-Bacterial Agents; Antibiotic Prophylaxis; Appendectomy; Appendicitis; Cefepime; Cephalosporins; Child; Child, Preschool; Drug Therapy, Combination; Female; Follow-Up Studies; Guideline Adherence; Humans; Infant; Infant, Newborn; Logistic Models; Male; Metronidazole; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Practice Guidelines as Topic; Preoperative Care; Retrospective Studies; Surgical Wound Infection; Treatment Outcome | 2017 |
Translational Efficacy of Humanized Exposures of Cefepime, Ertapenem, and Levofloxacin against Extended-Spectrum-β-Lactamase-Producing Escherichia coli in a Murine Model of Complicated Urinary Tract Infection.
Topics: Animals; Anti-Bacterial Agents; beta-Lactamases; beta-Lactams; Cefepime; Cephalosporins; Disease Models, Animal; Ertapenem; Escherichia coli Infections; Female; Humans; Levofloxacin; Mice, Inbred ICR; Microbial Sensitivity Tests; Urinary Tract Infections; Uropathogenic Escherichia coli | 2017 |
Semi-quantitative MALDI-TOF for antimicrobial susceptibility testing in Staphylococcus aureus.
Topics: Anti-Bacterial Agents; Cefepime; Cephalosporins; Ciprofloxacin; Drug Resistance, Multiple, Bacterial; Humans; Microbial Sensitivity Tests; Oxacillin; Sensitivity and Specificity; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Staphylococcal Infections; Staphylococcus aureus; Vancomycin | 2017 |
Prevalence and Transmission of Antimicrobial Resistance in a Vertically Integrated Veal Calf Production System.
Topics: Abattoirs; Animals; Anti-Bacterial Agents; Cattle; Cefepime; Cefotaxime; Cephalosporins; Ciprofloxacin; Drug Resistance, Multiple, Bacterial; Electrophoresis, Gel, Pulsed-Field; Escherichia coli; Feces; Food Contamination; Food Microbiology; Food Supply; Foodborne Diseases; Genes, Bacterial; Male; Prospective Studies; Red Meat; United States | 2017 |
Topics: Anti-Bacterial Agents; Cefepime; Ceftazidime; Cephalosporins; Ciprofloxacin; Drug Combinations; Drug Resistance, Multiple, Bacterial; Febrile Neutropenia; Humans; Iatrogenic Disease; Meropenem; Microbial Sensitivity Tests; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Pneumonia; Practice Guidelines as Topic; Pseudomonas aeruginosa; Pseudomonas Infections; Sepsis; Tazobactam; Thienamycins; Tobramycin | 2017 |
Cefepime versus carbapenems for the treatment of urinary tract infections caused by extended-spectrum β-lactamase-producing enterobacteriaceae.
Topics: Aged; Anti-Bacterial Agents; beta-Lactamases; Carbapenems; Cefepime; Cephalosporins; Enterobacteriaceae; Enterobacteriaceae Infections; Female; Humans; Male; Microbial Sensitivity Tests; Retrospective Studies; Urinary Tract Infections | 2018 |
Efficacy of Ceftriaxone, Cefepime, Doxycycline, Ciprofloxacin, and Combination Therapy for Vibrio vulnificus Foodborne Septicemia.
Topics: Animals; Anti-Bacterial Agents; Cefepime; Ceftriaxone; Cephalosporins; Ciprofloxacin; Doxycycline; Drug Synergism; Drug Therapy, Combination; Female; Foodborne Diseases; Humans; Mice; Seafood; Sepsis; Vibrio Infections; Vibrio vulnificus | 2017 |
Babesia microti infection and hemophagocytic lymphohistiocytosis in an immunocompetent patient.
Topics: Aged; Animals; Babesia microti; Babesiosis; Cefepime; Cephalosporins; Humans; Lymphohistiocytosis, Hemophagocytic; Male; Minnesota; Ticks; Vancomycin | 2017 |
Activity of Ceftolozane-Tazobactam and Ceftazidime-Avibactam against Beta-Lactam-Resistant Pseudomonas aeruginosa Isolates.
Topics: Anti-Bacterial Agents; Azabicyclo Compounds; beta-Lactam Resistance; beta-Lactamases; Cefepime; Ceftazidime; Cephalosporins; Drug Combinations; Gene Expression; Humans; Los Angeles; Meropenem; Microbial Sensitivity Tests; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Pseudomonas aeruginosa; Pseudomonas Infections; Tazobactam; Thienamycins | 2017 |
Impact of CLSI and EUCAST Cefepime breakpoint changes on the susceptibility reporting for Enterobacteriaceae.
Topics: Anti-Bacterial Agents; Bacterial Proteins; beta-Lactamases; Cefepime; Ceftriaxone; Cephalosporins; Drug Resistance, Multiple, Bacterial; Enterobacteriaceae; Enterobacteriaceae Infections; Escherichia coli; Humans; Klebsiella; Microbial Sensitivity Tests; Retrospective Studies | 2017 |
Potential of high-dose cefepime/tazobactam against multiresistant Gram-negative pathogens.
Topics: Anti-Bacterial Agents; Bacterial Proteins; beta-Lactamase Inhibitors; beta-Lactamases; Cefepime; Cephalosporins; Drug Combinations; Drug Resistance, Multiple, Bacterial; Enterobacteriaceae; Enterobacteriaceae Infections; Humans; Microbial Sensitivity Tests; Penicillanic Acid; Tazobactam | 2018 |
The use of cefepime as a carbapenem-sparing antibiotic for treating uncomplicated acute pyelonephritis caused by extended-spectrum β-lactamase producing Escherichia coli.
Topics: Aged; Anti-Bacterial Agents; beta-Lactamases; beta-Lactams; Carbapenems; Cefepime; Cephalosporins; Ertapenem; Escherichia coli; Escherichia coli Infections; Female; Hospitals, University; Humans; Male; Middle Aged; Pyelonephritis; Republic of Korea; Retrospective Studies; Risk Factors; Treatment Outcome | 2018 |
Clinical efficacy and safety of cefepime-tazobactam in hospitalized patients in South India.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; beta-Lactamases; Cefepime; Cephalosporins; Escherichia coli; Escherichia coli Infections; Female; Hospitalization; Humans; India; Klebsiella Infections; Klebsiella pneumoniae; Male; Middle Aged; Penicillanic Acid; Piperacillin; Tazobactam; Treatment Outcome; Young Adult | 2018 |
Activity of Ceftolozane-Tazobactam against Pseudomonas aeruginosa and Enterobacteriaceae Isolates Collected from Respiratory Tract Specimens of Hospitalized Patients in the United States during 2013 to 2015.
Topics: Anti-Bacterial Agents; beta-Lactamases; Cefepime; Ceftazidime; Cephalosporins; Drug Resistance, Multiple, Bacterial; Enterobacteriaceae; Enterobacteriaceae Infections; Gene Expression; Hospitalization; Humans; Isoenzymes; Meropenem; Microbial Sensitivity Tests; Piperacillin, Tazobactam Drug Combination; Plasmids; Pneumonia, Bacterial; Pseudomonas aeruginosa; Pseudomonas Infections; Respiratory System; Retrospective Studies; Tazobactam; United States | 2018 |
Clinical Outcomes in Patients With Gram-Negative Infections Treated With Optimized Dosing Cefepime Over Various Minimum Inhibitory Concentrations.
Topics: Adult; Aged; Anti-Bacterial Agents; Cefepime; Cephalosporins; Cohort Studies; Dose-Response Relationship, Drug; Enterobacteriaceae; Enterobacteriaceae Infections; Female; Gram-Negative Bacterial Infections; Humans; Male; Microbial Sensitivity Tests; Middle Aged; Retrospective Studies; Treatment Outcome | 2018 |
Cefepime-induced encephalopathy.
Topics: Anti-Bacterial Agents; Cefepime; Cephalosporins; Cerebral Palsy; Epilepsies, Myoclonic; Humans; Lung Abscess; Male; Middle Aged | 2018 |
Humanized Exposures of Cefiderocol, a Siderophore Cephalosporin, Display Sustained in vivo Activity against Siderophore-Resistant Pseudomonas aeruginosa.
Topics: Animals; Anti-Bacterial Agents; Azetidines; Cefepime; Cefiderocol; Cephalosporins; Disease Models, Animal; Drug Resistance, Multiple, Bacterial; Female; Humans; Levofloxacin; Mice; Mice, Inbred ICR; Microbial Sensitivity Tests; Monobactams; Pseudomonas aeruginosa; Pyridones; Siderophores; Sulfonamides | 2018 |
β-Lactam Combinations with Vancomycin Show Synergistic Activity against Vancomycin-Susceptible Staphylococcus aureus, Vancomycin-Intermediate S. aureus (VISA), and Heterogeneous VISA.
Topics: beta-Lactams; Cefazolin; Cefepime; Ceftaroline; Cephalosporins; Drug Synergism; Drug Therapy, Combination; Humans; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Nafcillin; Staphylococcal Infections; Vancomycin | 2018 |
Simultaneous determination of zidebactam and cefepime in dog plasma by LC-MS/MS and its application to pre-clinical pharmacokinetic study.
Topics: Animals; Azabicyclo Compounds; Cefepime; Cephalosporins; Chromatography, Liquid; Cyclooctanes; Dogs; Drug Stability; Linear Models; Male; Piperidines; Reproducibility of Results; Sensitivity and Specificity; Tandem Mass Spectrometry | 2018 |
Burn aggravated infected wart in a patient with type 2 diabetes: a medical challenge.
Topics: Aged; Anti-Bacterial Agents; Burns; Cefepime; Cephalosporins; Diabetes Mellitus, Type 2; Fluoroquinolones; Foot; Foot Diseases; Humans; Male; Moxifloxacin; Pakistan; Saudi Arabia; Staphylococcal Infections; Staphylococcus aureus; Warts | 2018 |
Cephalosporin antibiotics are weak blockers of GABAa receptor-mediated synaptic transmission in rat brain slices.
Topics: Animals; Anti-Bacterial Agents; Brain; Cefepime; Ceftriaxone; Cephalosporins; Epilepsy; GABA-A Receptor Antagonists; Inhibitory Postsynaptic Potentials; Ion Channel Gating; Ions; Neurons; Rats, Wistar; Receptors, GABA-A; Synaptic Transmission | 2018 |
Whole-Genome Analysis of an Extensively Drug-Resistance Empedobacter falsenii Strain Reveals Distinct Features and the Presence of a Novel Metallo-ß-Lactamase (EBR-2).
Topics: Amino Acid Sequence; Ampicillin; Anti-Bacterial Agents; beta-Lactamases; Cefepime; Cephalosporins; Cross Infection; Drug Resistance, Multiple, Bacterial; Flavobacteriaceae; Genome, Bacterial; Humans; Meropenem; Microbial Sensitivity Tests; Penicillin G; Thienamycins | 2018 |
Plasmid-Mediated AmpC β-Lactamase and Underestimation of Extended-Spectrum β-Lactamase in Cefepime-Susceptible Elevated-Ceftazidime-MIC Enterobacteriaceae Isolates.
Topics: Anti-Bacterial Agents; beta-Lactam Resistance; beta-Lactamases; Cefepime; Ceftazidime; Cephalosporins; Diagnostic Errors; Enterobacteriaceae; Enterobacteriaceae Infections; Genotype; Humans; Japan; Microbial Sensitivity Tests; Phenotype | 2018 |
[Analysis of the distribution characteristics and drug resistance of non-fermenting bacterial infection in intensive care unit from 2009 to 2015]
Topics: Acinetobacter baumannii; Anti-Bacterial Agents; Bacterial Infections; Cefepime; Cefoperazone; Cephalosporins; Cross Infection; Drug Resistance; Drug Resistance, Bacterial; Gram-Negative Bacteria; Humans; Imipenem; Intensive Care Units; Meropenem; Microbial Sensitivity Tests; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Pseudomonas aeruginosa; Retrospective Studies; Thienamycins | 2016 |
Mechanisms of Resistance in Clinical Isolates of
Topics: Anti-Bacterial Agents; Bacterial Proteins; Carrier Proteins; Cefepime; Ceftazidime; Cephalosporins; Drug Resistance, Bacterial; Electron Transport Complex IV; Enterobacter cloacae; Enterobacteriaceae Infections; Humans; Mitochondrial Proteins; Nuclear Proteins | 2018 |
Infections by OXA-48-like-producing Klebsiella pneumoniae non-co-producing extended-spectrum beta-lactamase: Can they be successfully treated with cephalosporins?
Topics: Aged; Anti-Bacterial Agents; beta-Lactamases; Carbapenems; Cefepime; Ceftriaxone; Cephalosporins; Female; Humans; Klebsiella Infections; Klebsiella pneumoniae; Male; Middle Aged; Nephritis; Retrospective Studies; Spain | 2019 |
A Novel VIM-Type Metallo-β-Lactamase Variant, VIM-60, with Increased Hydrolyzing Activity against Fourth-Generation Cephalosporins in Pseudomonas aeruginosa Clinical Isolates in Japan.
Topics: Anti-Bacterial Agents; beta-Lactamases; Cefepime; Cefpirome; Cephalosporins; Humans; Hydrolysis; Japan; Microbial Sensitivity Tests; Pseudomonas aeruginosa; Pseudomonas Infections | 2019 |
Adequacy of empiric gram-negative coverage for septic patients at an academic medical center.
Topics: Academic Medical Centers; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Cefepime; Cephalosporins; Female; Gram-Negative Bacteria; Humans; Levofloxacin; Male; Meropenem; Microbial Sensitivity Tests; Middle Aged; Piperacillin; Piperacillin, Tazobactam Drug Combination; Retrospective Studies; Sepsis; Shock, Septic; Virginia; Young Adult | 2019 |
Cephalosporin-related neurotoxicity: Metabolic encephalopathy or non-convulsive status epilepticus?
Topics: Anticonvulsants; Brain Diseases, Metabolic; Cefepime; Cephalosporins; Confusion; Consciousness Disorders; Electroencephalography; Female; Humans; Male; Myoclonus; Neurotoxicity Syndromes; Seizures; Status Epilepticus | 2019 |
Efficacy of human-simulated bronchopulmonary exposures of cefepime, zidebactam and the combination (WCK 5222) against MDR Pseudomonas aeruginosa in a neutropenic murine pneumonia model.
Topics: Animals; Anti-Bacterial Agents; Azabicyclo Compounds; Cefepime; Cephalosporins; Cyclooctanes; Disease Models, Animal; Drug Resistance, Multiple, Bacterial; Drug Therapy, Combination; Female; Healthy Volunteers; Humans; Lung; Mice; Microbial Sensitivity Tests; Neutropenia; Piperidines; Pneumonia, Bacterial; Pseudomonas aeruginosa; Pseudomonas Infections; Specific Pathogen-Free Organisms | 2020 |
Heteroresistance to cefepime in Pseudomonas aeruginosa bacteraemia.
Topics: Adult; Anti-Bacterial Agents; Bacteremia; Cefepime; Cephalosporins; China; Drug Resistance, Bacterial; Female; Humans; Male; Middle Aged; Pseudomonas aeruginosa; Pseudomonas Infections | 2020 |
A retrospective study to determine the cefepime-induced neurotoxicity threshold in hospitalized patients.
Topics: Adult; Anti-Bacterial Agents; Cefepime; Cephalosporins; Humans; Neurotoxicity Syndromes; Retrospective Studies | 2020 |
Clinical Evolution of AmpC-Mediated Ceftazidime-Avibactam and Cefiderocol Resistance in Enterobacter cloacae Complex Following Exposure to Cefepime.
Topics: Anti-Bacterial Agents; Azabicyclo Compounds; Bacterial Proteins; beta-Lactamases; Cefepime; Cefiderocol; Ceftazidime; Cephalosporins; Drug Combinations; Enterobacter cloacae; Humans; Microbial Sensitivity Tests | 2020 |
Bacteria Keep Reminding Us: There Are No Silver Bullets.
Topics: Azabicyclo Compounds; Cefepime; Cefiderocol; Ceftazidime; Cephalosporins; Drug Combinations; Enterobacter cloacae; Humans; Silver | 2020 |
In vivo pharmacodynamics of new-generation β-lactamase inhibitor taniborbactam (formerly VNRX-5133) in combination with cefepime against serine-β-lactamase-producing Gram-negative bacteria.
Topics: Animals; Anti-Bacterial Agents; beta-Lactamase Inhibitors; beta-Lactamases; Borinic Acids; Carboxylic Acids; Cefepime; Cephalosporins; Humans; Mice; Microbial Sensitivity Tests; Pseudomonas aeruginosa; Serine | 2020 |
An update on cefepime and its future role in combination with novel β-lactamase inhibitors for MDR Enterobacterales and Pseudomonas aeruginosa.
Topics: Animals; Anti-Bacterial Agents; Azabicyclo Compounds; beta-Lactamase Inhibitors; beta-Lactamases; Borinic Acids; Carboxylic Acids; Cefepime; Cephalosporins; Microbial Sensitivity Tests; Pseudomonas aeruginosa; Triazoles | 2021 |
In vivo activity of WCK 4282 (high-dose cefepime/tazobactam) against serine β-lactamase-producing Enterobacterales and Pseudomonas aeruginosa in the neutropenic murine thigh infection model.
Topics: Animals; Anti-Bacterial Agents; beta-Lactamases; Cefepime; Cephalosporins; Escherichia coli; Mice; Microbial Sensitivity Tests; Pseudomonas aeruginosa; Serine; Tazobactam; Thigh | 2021 |
Using precision dosing to minimize cefepime-induced neurotoxicity: The challenge of targets.
Topics: Anti-Bacterial Agents; Cefepime; Cephalosporins; Humans | 2021 |
Cefepime/tazobactam compared with other tazobactam combinations against problem Gram-negative bacteria.
Topics: Anti-Bacterial Agents; Bacterial Proteins; beta-Lactamases; Cefepime; Cephalosporins; Drug Resistance, Multiple, Bacterial; Enterobacteriaceae; Gram-Negative Bacteria; Gram-Negative Bacterial Infections; Humans; Microbial Sensitivity Tests; Piperacillin, Tazobactam Drug Combination; Pseudomonas aeruginosa; Tazobactam | 2021 |
Activity of cefepime/zidebactam (WCK 5222) against 'problem' antibiotic-resistant Gram-negative bacteria sent to a national reference laboratory.
Topics: Anti-Bacterial Agents; Azabicyclo Compounds; beta-Lactamases; Cefepime; Cephalosporins; Cyclooctanes; Gram-Negative Bacteria; Laboratories; Microbial Sensitivity Tests; Piperidines; Pseudomonas aeruginosa | 2021 |
Negative myoclonus as the leading symptom in acute cefepime neurotoxicity.
Topics: Aged, 80 and over; Anti-Bacterial Agents; Brain Ischemia; Cefepime; Cephalosporins; Female; Humans; Myoclonus; Piperacillin, Tazobactam Drug Combination; Stroke | 2021 |
Comparative in vivo activity of human-simulated plasma and epithelial lining fluid exposures of WCK 5222 (cefepime/zidebactam) against KPC- and OXA-48-like-producing Klebsiella pneumoniae in the neutropenic murine pneumonia model.
Topics: Animals; Anti-Bacterial Agents; Azabicyclo Compounds; beta-Lactamases; Cefepime; Cephalosporins; Cyclooctanes; Humans; Klebsiella pneumoniae; Mice; Microbial Sensitivity Tests; Piperidines; Pneumonia | 2021 |
Comment on: An update on cefepime and its future role in combination with novel β-lactamase inhibitors for MDR Enterobacterales and Pseudomonas aeruginosa.
Topics: beta-Lactamase Inhibitors; Cefepime; Cephalosporins; Microbial Sensitivity Tests; Pseudomonas aeruginosa | 2021 |
In vitro evolution of cefepime/zidebactam (WCK 5222) resistance in Pseudomonas aeruginosa: dynamics, mechanisms, fitness trade-off and impact on in vivo efficacy.
Topics: Animals; Anti-Bacterial Agents; Azabicyclo Compounds; beta-Lactamases; Cefepime; Cephalosporins; Cyclooctanes; Mice; Microbial Sensitivity Tests; Piperidines; Pseudomonas aeruginosa | 2021 |
How fluoroquinolone preauthorization affects third- and fourth-generation cephalosporin use and resistance in a large academic hospital.
Topics: Anti-Bacterial Agents; Cefepime; Ceftazidime; Ceftriaxone; Cephalosporin Resistance; Cephalosporins; Fluoroquinolones; Gram-Negative Bacteria; Hospitals; Humans; Microbial Sensitivity Tests; Retrospective Studies | 2022 |
Molecular epidemiology of cefotaxime-resistant but ceftazidime-susceptible Enterobacterales and evaluation of the in vitro bactericidal activity of ceftazidime and cefepime.
Topics: Anti-Bacterial Agents; beta-Lactamases; Cefepime; Cefotaxime; Ceftazidime; Cephalosporins; Drug Resistance, Bacterial; Enterobacteriaceae; Escherichia coli; Klebsiella pneumoniae; Microbial Sensitivity Tests; Molecular Epidemiology; Proteus mirabilis | 2021 |
An update on cefepime and its future role in combination with novel β-lactamase inhibitors for MDR Enterobacterales and Pseudomonas aeruginosa--authors' response.
Topics: beta-Lactamase Inhibitors; Cefepime; Cephalosporins; Microbial Sensitivity Tests; Pseudomonas aeruginosa | 2021 |
Clinical exposure-response relationship of cefepime/taniborbactam against Gram-negative organisms in the murine complicated urinary tract infection model.
Topics: Animals; Anti-Bacterial Agents; Azabicyclo Compounds; beta-Lactamases; Borinic Acids; Carboxylic Acids; Cefepime; Cephalosporins; Humans; Mice; Microbial Sensitivity Tests; Urinary Tract Infections | 2022 |
Cefepime Precision Dosing Tool: from Standard to Precise Dose Using Nonparametric Population Pharmacokinetics.
Topics: Adult; Anti-Bacterial Agents; Cefepime; Cephalosporins; Child; Humans; Microbial Sensitivity Tests | 2022 |
Antimicrobial activity of high-dose cefepime-tazobactam (WCK 4282) against a large collection of gram-negative organisms collected worldwide in 2018 and 2019.
Topics: Anti-Bacterial Agents; Cefepime; Cephalosporins; Humans; Meropenem; Microbial Sensitivity Tests; Pseudomonas aeruginosa; Tazobactam | 2022 |
Smaller but more frequent dosing of cefepime in the treatment of febrile neutropenia.
Topics: Anti-Bacterial Agents; Cefepime; Cephalosporins; Cohort Studies; Febrile Neutropenia; Fever; Humans; Retrospective Studies; Vancomycin | 2022 |
Cefepime-induced Neurotoxicity: A Retrospective Cohort Study in a South-Indian Tertiary Healthcare Facility.
Topics: Anti-Bacterial Agents; Cefepime; Cephalosporins; Humans; Neurotoxicity Syndromes; Renal Insufficiency; Retrospective Studies; Tertiary Healthcare | 2023 |
Inoculum effects of cefepime/zidebactam (WCK 5222) and ertapenem/zidebactam (WCK 6777) for Enterobacterales in relation to β-lactamase type and enhancer effect, as tested by BSAC agar dilution.
Topics: Agar; Animals; Anti-Bacterial Agents; Azabicyclo Compounds; beta-Lactamases; Cefepime; Cephalosporins; Cyclooctanes; Ertapenem; Microbial Sensitivity Tests; Piperidines | 2022 |
Cefepime/Enmetazobactam Is a Clinically Effective Combination Targeting Extended-Spectrum β-Lactamase-Producing
Topics: Anti-Bacterial Agents; Azabicyclo Compounds; beta-Lactamases; Cefepime; Cephalosporins; Microbial Sensitivity Tests; Triazoles | 2022 |
Cefepime-induced encephalopathy in a COVID-19 patient: a case report.
Topics: Anti-Bacterial Agents; Brain Diseases; Cefepime; Cephalosporins; COVID-19; COVID-19 Drug Treatment; Humans; Male; Middle Aged | 2022 |
Retrospective Cohort Study of Clinical Efficacy and Safety of Cefozopran for Treating Febrile Neutropenia during Chemotherapy in Patients with Lung Cancer.
Topics: Anti-Bacterial Agents; Cefepime; Cefozopran; Cephalosporins; Febrile Neutropenia; Humans; Lung Neoplasms; Retrospective Studies; Treatment Outcome | 2022 |
Antimicrobial activity of cefepime/zidebactam (WCK 5222), a β-lactam/β-lactam enhancer combination, against clinical isolates of Gram-negative bacteria collected worldwide (2018-19).
Topics: Anti-Bacterial Agents; Azabicyclo Compounds; Carbapenems; Cefepime; Ceftazidime; Cephalosporins; Cyclooctanes; Enterobacteriaceae; Gram-Negative Bacteria; Hydrazines; Lactams; Microbial Sensitivity Tests; Piperidines; Pseudomonas aeruginosa; Tazobactam | 2022 |
Activity of cefiderocol, imipenem/relebactam, cefepime/taniborbactam and cefepime/zidebactam against ceftolozane/tazobactam- and ceftazidime/avibactam-resistant Pseudomonas aeruginosa.
Topics: Anti-Bacterial Agents; Azabicyclo Compounds; beta-Lactamases; Borinic Acids; Carboxylic Acids; Cefepime; Cefiderocol; Ceftazidime; Cephalosporins; Cyclooctanes; Humans; Imipenem; Piperidines; Pseudomonas aeruginosa; Pseudomonas Infections; Tazobactam | 2022 |
Treatment options for neonatal infections in the post-cefotaxime era.
Topics: Ampicillin; Anti-Bacterial Agents; Calcium; Cefepime; Cefotaxime; Ceftazidime; Ceftriaxone; Cephalosporins; Communicable Diseases; Gentamicins; Humans; Infant, Newborn; Infant, Newborn, Diseases; Microbial Sensitivity Tests | 2022 |
Proteomic Investigation of the Antibacterial Mechanism of Cefiderocol against Escherichia coli.
Topics: Acetylcysteine; Anti-Bacterial Agents; Antioxidants; Ascorbic Acid; Cefepime; Cefiderocol; Ceftazidime; Cephalosporins; Deferoxamine; Escherichia coli; Flavin-Adenine Dinucleotide; Hydrogen Peroxide; Iron; NAD; NADP; Proteomics; Quinones; Reactive Oxygen Species; Siderophores; Sulfur | 2022 |
Time to defervescence evaluation for extended- vs. standard-infusion cefepime in patients with acute leukemia and febrile neutropenia.
Topics: Anti-Bacterial Agents; beta-Lactams; Cefepime; Cephalosporins; Febrile Neutropenia; Humans; Leukemia, Myeloid, Acute; Retrospective Studies | 2022 |
Cephalosporin translocation across enterobacterial OmpF and OmpC channels, a filter across the outer membrane.
Topics: Cefepime; Cefotaxime; Ceftazidime; Cephalosporins; Chromatography, Liquid; Enterobacteriaceae; Escherichia coli; Lipid Bilayers; Monobactams; Porins; Tandem Mass Spectrometry | 2022 |
Cefepime pharmacodynamic targets against Enterobacterales employing neutropenic murine lung infection and in vitro pharmacokinetic models.
Topics: Animals; Anti-Bacterial Agents; Cefepime; Cephalosporins; Lung; Mice; Microbial Sensitivity Tests; Tazobactam | 2022 |
Pediatric drug utilization evaluation of cefepime and piperacillin/tazobactam.
Topics: Anti-Bacterial Agents; Cefepime; Cephalosporins; Child; Drug Utilization Review; Humans; Piperacillin, Tazobactam Drug Combination; Retrospective Studies | 2022 |
Prevalence of Efflux Pump and Porin-Related Antimicrobial Resistance in Clinical
Topics: Anti-Bacterial Agents; Bacterial Proteins; beta-Lactamases; Carbapenems; Cefazolin; Cefepime; Cefoxitin; Ceftazidime; Ceftriaxone; Cephalosporins; Drug Resistance, Bacterial; Ertapenem; Humans; Imipenem; Iraq; Klebsiella pneumoniae; Microbial Sensitivity Tests; Porins; Prevalence | 2022 |
Phenotypic and genotypic profile of ceftolozane/tazobactam-non-susceptible, carbapenem-resistant Pseudomonas aeruginosa.
Topics: Anti-Bacterial Agents; Azabicyclo Compounds; beta-Lactamases; Carbapenems; Cefepime; Ceftazidime; Cephalosporins; Drug Combinations; Humans; Microbial Sensitivity Tests; Pseudomonas aeruginosa; Pseudomonas Infections; Tazobactam | 2022 |
In vivo pharmacokinetic/pharmacodynamic evaluation of cefepime/taniborbactam combination against cefepime-non-susceptible Enterobacterales and Pseudomonas aeruginosa in a murine pneumonia model.
Topics: Animals; Anti-Bacterial Agents; beta-Lactamases; Cefepime; Cephalosporins; Healthcare-Associated Pneumonia; Humans; Mice; Microbial Sensitivity Tests; Pneumonia; Pseudomonas aeruginosa | 2023 |
Impact of surfactants and other body fluids on in vitro activity of a novel β-lactamase inhibitor enmetazobactam in combination with cefepime against clinical isolates of Klebsiella pneumoniae.
Topics: Anti-Bacterial Agents; beta-Lactamase Inhibitors; beta-Lactamases; Body Fluids; Cefepime; Cephalosporins; Daptomycin; Escherichia coli; Humans; Klebsiella pneumoniae; Microbial Sensitivity Tests; Monobactams; Staphylococcus aureus; Surface-Active Agents | 2023 |
In vitro activity of cefepime/zidebactam and cefepime/taniborbactam against aztreonam/avibactam-resistant NDM-like-producing Escherichia coli clinical isolates.
Topics: Anti-Bacterial Agents; Azabicyclo Compounds; Aztreonam; beta-Lactamase Inhibitors; beta-Lactamases; Cefepime; Cephalosporins; Escherichia coli; Microbial Sensitivity Tests | 2023 |
Cefepime Induced Encephalopathy in a Non-dialysis Dependent Chronic Kidney Disease Patient: A Case Report.
Topics: Anti-Bacterial Agents; Brain Diseases; Cefepime; Cephalosporins; Female; Humans; Middle Aged; Renal Insufficiency, Chronic | 2023 |
Effectiveness of third-generation cephalosporins or piperacillin compared with cefepime or carbapenems for severe infections caused by wild-type AmpC β-lactamase-producing Enterobacterales: A multi-centre retrospective propensity-weighted study.
Topics: Anti-Bacterial Agents; beta-Lactamases; Carbapenems; Cefepime; Cephalosporins; Humans; Piperacillin; Piperacillin, Tazobactam Drug Combination; Retrospective Studies | 2023 |
Case Commentary: Successful Use of Cefepime/Zidebactam (WCK 5222) as a Salvage Therapy for the Treatment of Disseminated Extensively Drug-Resistant New Delhi Metallo-β-Lactamase-Producing
Topics: Adult; Anti-Bacterial Agents; Anti-Infective Agents; Azabicyclo Compounds; beta-Lactamases; Cefepime; Cephalosporins; Humans; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma; Pseudomonas aeruginosa; Pseudomonas Infections; Salvage Therapy | 2023 |
Compassionate use of a novel β-lactam enhancer-based investigational antibiotic cefepime/zidebactam (WCK 5222) for the treatment of extensively-drug-resistant NDM-expressing Pseudomonas aeruginosa infection in an intra-abdominal infection-induced sepsis p
Topics: Anti-Bacterial Agents; beta-Lactamases; Cefepime; Cephalosporins; Compassionate Use Trials; Humans; Intraabdominal Infections; Microbial Sensitivity Tests; Monobactams; Polymyxins; Pseudomonas aeruginosa; Pseudomonas Infections; Sepsis | 2023 |
Should cefepime be used for any bloodstream infections caused by ceftriaxone-resistant, cefepime-susceptible Enterobacterales?
Topics: Anti-Bacterial Agents; beta-Lactamases; Cefepime; Ceftriaxone; Cephalosporins; Humans; Microbial Sensitivity Tests; Sepsis | 2023 |
Exploring fluorescence of metal nanoparticles for effective utility in drug sensing: A Promising ''on-off'' fluorescence probe for analysis of cephalosporins is fabricated.
Topics: Cefepime; Ceftriaxone; Cephalosporins; Fluorescent Dyes; Metal Nanoparticles; Silver; Spectrometry, Fluorescence | 2023 |