Page last updated: 2024-08-24

cephalosporin c and cefditoren

cephalosporin c has been researched along with cefditoren in 115 studies

Research

Studies (115)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	11 (9.57)	18.2507
2000's	72 (62.61)	29.6817
2010's	23 (20.00)	24.3611
2020's	9 (7.83)	2.80

Authors

Authors	Studies
Bhogal, H; Clark, S; Dencer, CA; Felmingham, D; Ghosh, G; Grüneberg, RN; Leakey, A; Mehta, MD; Ridgway, GL; Robbins, MJ	1
Coronel, P; Fernández-Roblas, R; Gimeno, M; López, JC; Ramos, JM; Soriano, F	1
Appelbaum, PC; Jacobs, MR; Spangler, SK	2
Coronel, P; Fernández-Roblas, R; García-Corbeira, P; Gimeno, M; Jiménez, M; Soriano, F	1
Abe, T; Domon, H; Fukuoka, T; Harasaki, T; Hirasawa, A; Ishii, C; Iwata, M; Kakuta, M; Kawada, H; Koga, T; Kubota, M; Kuwahara, S; Masuda, N; Ohya, S; Sakagawa, E; Takenouchi, T; Utsui, Y; Yasuda, H	1
Barrett, MS; Biedenbach, DJ; Croco, MA; Jones, RN	1
Akiyama, H; Arata, J; Kanzaki, H; Tada, J; Yamasaki, O	1
Appelbaum, PC; Jacobs, MR; Kelly, LM	1
Nakanishi, T; Nasu, T; Nishino, T; Okamoto, K	1
Hanaki, H; Hiramatsu, K; Inaba, Y	1
Hasegawa, M; Kobayashi, I; Koyama, H; Matsuzaki, K; Nishiyama, T; Saika, T	1
Beach, ML; Biedenbach, DJ; Johnson, DM; Jones, RN; Pfaller, MA	1
Biedenbach, DJ; Johnson, DM; Jones, RN	1
Dubois, J; St-Pierre, C	1
Barry, AL; Brown, SD; Fuchs, PC	1
Hijioka, S; Inoue, S; Kugo, Y; Nishimura, T; Oguni, T; Sugiki, M; Sugita, K; Uemura, T; Wakamiya, E; Yoshikawa, K	1
Platt, D; Rieck, W	1
Hashido, H; Ishigo, S; Iwata, I; Matsubara, S; Matsukawa, Y; Mikamo, H; Sawamura, H; Suematsu, H; Tamaya, T	1
Barry, AL; Brown, SD; Fuchs, PC; Traczewski, MM	1
Al-Lahham, A; Lütticken, R; Reinert, RR	1
Thompson, CA	1
Guay, DR	1
Critchley, IA; Draghi, DC; Jones, ME; Karlowsky, JA; Sahm, DF; Thornsberry, C	2
Appelbaum, PC; Clark, CL; Dewasse, BE; Ednie, LM; Jacobs, MR; Nagai, K; Pankuch, GA	1
Bucko, AD; Hom, R; Hunt, BJ; Kidd, SL	1
Balbisi, EA	1
Abe, T; Fukuoka, T; Ito, K; Sato, Y; Sei, M	1
Odagiri, S; Shimada, J; Takahashi, H; Watanuki, Y	1
Kataoka, S	1
Uno, Y	1
Furukawa, M; Ito, M	1
Iwata, T; Tajima, T	1
Yokoyama, M	1
Ubukata, K	1
Sakata, H	2
Suzuki, K	1
Ogata, H	1
Shibata, M	1
Ito, M	1
Ichimaru, T	1
Hajdú, E; Marton, A; Nagy, E	1
Hasegawa, M; Kobayashi, I; Matsuzaki, K; Sato, Y; Shikano, M; Watabe, E; Yamanaka, N; Yoshimori, K	1
Cartier, LL; Cheung, BW; Giebink, GS; Sawchuk, RJ; Zhu, T	1
Kaye, KM; Martin, SI	1
Cao, LD; Naruhiko, I; Nobue, T; Yoichi, K	1
Chimura, T; Murayama, K	1
Kandikere, VN; Mudigonda, K; Nirogi, RV; Shrivastava, W	1
Baek, JY; Ko, KS; Lee, JY; Lee, MY; Lee, NY; Oh, WS; Park, S; Peck, KR; Song, JH; Suh, JY	1
Arakawa, S; Deguchi, T; Egashira, T; Fujime, M; Fujita, K; Fukuhara, Y; Furuya, N; Hirakata, Y; Hirose, T; Igari, J; Imafuku, Y; Ishibashi, K; Ishihara, S; Kamidono, S; Kitamura, M; Kobayashi, Y; Kohno, S; Kondo, A; Konishi, T; Kumamoto, Y; Kumon, H; Kunishima, Y; Matsuda, J; Matsuda, S; Matsukawa, M; Matsumoto, T; Monden, K; Murai, M; Muratani, T; Naito, S; Nakano, M; Oguri, T; Oka, T; Ooe, H; Sato, S; Shigeta, S; Suzutani, T; Tsukamoto, T; Uchida, H; Watanabe, K; Yamaguchi, K; Yamaguti, O; Yoshida, H	1
Aguilar, L; Casal, J; Coronel, P; Fenoll, A; Giménez, MJ; Gimeno, M; Robledo, O	1
Aguilar, L; Alou, L; Cafini, F; Echeverría, O; Giménez, MJ; Gómez-Lus, ML; González, N; Sevillano, D; Torrico, M	1
Aguilar, L; Coronel, P; Galarza, P; Giménez, MJ; Martín, E; Vázquez, JA	1
Hikida, M; Maebashi, K; Mikuniya, T; Niida, M; Shimizu, A; Ubukata, K	1
Aguilar, L; Alou, L; Coronel, P; Echeverría, O; Giménez, MJ; González, N; Prieto, J; Sevillano, D; Torrico, M	1
Aguilar, L; Alou, L; Cafini, F; Coronel, P; Echeverría, O; Giménez, MJ; González, N; Prieto, J; Sevillano, D; Torrico, M	2
Bulitta, J; Drusano, GL; Hinder, M; Kinzig-Schippers, M; Lodise, TP; Loos, U; Sörgel, F; Vogel, F	1
Azanza, JR; Campanero, MA; Coronel, P; Gimeno, M; Honorato, J; Quetglas, EG; Sádaba, B	1
Aguilar, L; Coronel, P; Fenoll, A; Giménez, MJ; Gimeno, M; Granizo, JJ; Robledo, O; Tarragó, D	1
Aguilar, L; Alou, L; Echeverria, O; Gomez-Lus, ML; Gonzalez, N; Prieto, J; Sevillano, D	1
Jung, DS; Ko, KS; Kwon, KT; Lee, MY; Lee, NY; Peck, KR; Song, JH; Suh, JY	1
Baba, N; Miyara, T; Ohsawa, F; Saito, J; Takeuchi, Y; Watanabe, T; Yamada, M	1
Aguilar, L; Alou, L; Cafini, F; Coronel, P; Giménez, MJ; González, N; Prieto, J; Relaño, MT; Sevillano, D; Torrico, M	1
Aguilar, L; Coronel, P; Gimenez, MJ; Granizo, JJ; Honorato, J; Sádaba, B; Sevillano, D	1
Coronel, P; del Prado, G; Díaz, C; García-Rodas, R; Gimeno, M; Gracia, M; Granizo, JJ; Huelves, L; Naves, PL; Ponte, MC; Ruiz, V; Soriano, F	1
Ida, T; Kato, Y; Maebashi, K; Sanbongi, Y; Takahata, S	1
Biedenbach, DJ; Fritsche, TR; Jones, RN	2
Aguilar, L; Barberán, J; Coronel, P; Giménez, MJ; Gimeno, M; Granizo, JJ	1
Aguilar, L; Alou, L; Cafini, F; Coronel, P; Fenoll, A; Giménez, MJ; González, N; Prieto, J; Sevillano, D; Torrico, M	1
Becerril, R; Castillo, FJ; Coronel, P; Durán, E; Gimeno, M; Gómez-Lus, R; Oca, M; Rubio-Calvo, C; Seral, C; Suárez, L	1
Fadda, G; Mattina, R; Mezzatesta, ML; Nicoletti, G; Palù, G; Rossano, F; Schito, GC; Stefani, S; Tufano, MA	1
Marco, JA; Naranjo, OR; Rodríguez de Castro, F; Violán, JS	1
Aguilar, L; Alou, L; Cafini, F; Coronel, P; Giménez, MJ; González, N; Prieto, J; Sevillano, D; Torrico, M	2
Biedenbach, DJ; Jones, RN	1
Liu, K; Liu, Q; Ma, X; Peng, J; Wang, C; Wu, J; Zhang, Q	1
Aguilar, L; Coronel, P; Gimenez, MJ; Gimeno, M; Granizo, JJ; Prieto, J	1
Gona, F; Marchese, G; Mezzatesta, ML; Nicoletti, G; Nicolosi, D; Stefani, S; Toscano, MA	1
Barberán, J; Mensa, J	1
Bouza, E; Cercenado, E; Coronel, P; Cuevas, O; Gimeno, M; Marín, M	1
Carlone, NA; Cocuzza, C; Furneri, PM; Musumeci, R; Nicoletti, G; Pilloni, AP; Prenna, M; Rigoli, R; Tempera, G; Tufano, MA; Tullio, V; Vitali, LA	1
Aguilar, L; Alou, L; Cafini, F; Coronel, P; García, E; Giménez, MJ; González, N; Prieto, J; Ramos-Sevillano, E; Sevillano, D; Torrico, M; Yuste, J	1
Kaku, T; Kato, Y; Liu, K; Liu, Q; Meng, Q; Sun, H; Wang, C	1
Hur, JK; Kang, JH; Kim, JH; Lee, KY; Lee, SY	1
Aguilar, L; Giménez, MJ; Soriano, F	1
Aguilar, L; Alou, L; Cafini, F; Coronel, P; Giménez, MJ; González, N; López, AM; Prieto, J; Sevillano, D; Torrico, M	1
Cao, B; Chen, M; Chu, Y; Duan, Q; Hu, Y; Liu, Y; Sun, H; Sun, Z; Wang, H; Xu, Y; Yang, Q; Yu, Y; Zhang, R; Zhuo, C	1
Aguilar, L; Alou, L; Cafini, F; García, E; Giménez, MJ; Navarro, A; Ramos-Sevillano, E; Rodríguez-Sosa, C; Sevillano, D; Yuste, J	1
Deliolanis, I; Giamarellou, H; Hatzaki, D; Katsarolis, I; Lambri, N; Lebessi, E; Nikolopoulos, GK; Poulakou, G; Souli, M	1
Chiba, N; Morozumi, M; Ubukata, K	1
Do, HS; Jang, HS; Kwon, JJ; Lee, ES; Lee, JY; Lim, JH; Rim, JS	1
Chen, H; Li, H; Wang, H; Wang, Q; Wang, Z; Zhang, F; Zhao, C	1
Blasi, F; Braido, F; Di Marco, F; Santus, P; Scichilone, N	1
Matsumoto, K; Mitomi, N; Sato, N; Shibasaki, S; Shitara, Y	1
Abdelnour, A; Arguedas, A; Guevara, S; Soley, C; Ulloa, C	1
Bachiller-Luque, P; Briongos-Figuero, LS; Carreres-Rodríguez, A; Mena-Martín, FJ; Pastor-Mancisidor, L	1
Blasi, F; Concia, E; Del Prato, B; Giusti, M; Mazzei, T; Novelli, A; Polistena, B; Rossi, A; Stefani, S	1
Barberán, J; Sánchez Artola, B	1
Huo, X; Liu, K; Liu, Z; Ma, X; Meng, Q; Peng, J; Sun, H; Sun, P; Wang, C; Wang, H	1
Adachi, Y; Iwata, S; Mokuno, E; Morozumi, M; Sakuma, M; Tajima, T; Ubukata, K	1
Chun, J; Miura, NN; Miyabe, C; Miyabe, Y; Miyasaka, M; Miyasaka, N; Nagai, J; Nanki, T; Ohno, N; Tsuboi, R; Ueda, H	1
Attanasio, V; Bernardo, M; Capoluongo, N; Carozza, A; Di Luca, M; Pallotto, C; Palmiero, G; Severino, S; Tascini, C	1
Abril-Pérez, C; Botella-Estrada, R; Roca-Ginés, J; Sánchez-Arráez, J; Torres-Navarro, I	1
Cabañero-Navalón, MD; García-Bustos, V; Salavert Lletí, M	1
Coronel, P; Del Río, I; Domenech, M; Gimeno, M; González-Camacho, F; Llamosí, M; López-Ruiz, B; Sempere, J; Yuste, J	1
Martín Guerra, JM; Moreta Rodríguez, M	1
Batchelder, HR; Lamichhane, G; Nuermberger, EL; Panthi, CM; Rimal, B; Story-Roller, E; Tabor, C; Townsend, CA	1
Coronel, P; Del Río, I; Domenech, M; Gimeno, M; González-Camacho, F; Lago, D; Llamosí, M; López Ruiz, B; Pérez-García, C; Sempere, J; Yuste, J	1
Coronel, P; Domenech, M; Gimeno, M; Llamosí, M; Sempere, J; Yuste, J	1
Acquasanta, A; Flammini, S; Giuliano, S; Martini, L; Sbrana, F; Tascini, C	1

Reviews

12 review(s) available for cephalosporin c and cefditoren

Article	Year
Review of cefditoren, an advanced-generation, broad-spectrum oral cephalosporin. Clinical therapeutics, 2001, Volume: 23, Issue:12 Topics: Administration, Oral; Adolescent; Adult; Area Under Curve; Bacterial Infections; Cephalosporins; Chromatography, High Pressure Liquid; Half-Life; Humans; Intestinal Absorption; Microbial Sensitivity Tests; Randomized Controlled Trials as Topic	2001
Cefditoren, a new aminothiazolyl cephalosporin. Pharmacotherapy, 2002, Volume: 22, Issue:10 Topics: Acute Disease; Bacterial Infections; Bronchitis, Chronic; Cephalosporins; Clinical Trials as Topic; Community-Acquired Infections; Drug Interactions; Humans; Maxillary Sinusitis; Pharyngitis; Pneumonia, Bacterial; Skin Diseases, Bacterial	2002
Beta-lactam antibiotics: newer formulations and newer agents. Infectious disease clinics of North America, 2004, Volume: 18, Issue:3 Topics: Amoxicillin-Potassium Clavulanate Combination; Anti-Bacterial Agents; beta-Lactams; Cefepime; Cephalosporins; Ertapenem; Humans; Lactams; United States	2004
New antimicrobial molecules and new antibiotic strategies. Seminars in respiratory and critical care medicine, 2009, Volume: 30, Issue:2 Topics: Acetamides; Anti-Infective Agents; beta-Lactams; Cephalosporins; Community-Acquired Infections; Drug Design; Drug Resistance, Multiple, Bacterial; Drug Therapy, Combination; Ertapenem; Fluoroquinolones; Humans; Ketolides; Linezolid; Lipopeptides; Oxazolidinones; Pneumonia, Bacterial; Practice Guidelines as Topic	2009
Update of cefditoren activity tested against community-acquired pathogens associated with infections of the respiratory tract and skin and skin structures, including recent pharmacodynamic considerations. Diagnostic microbiology and infectious disease, 2009, Volume: 64, Issue:2 Topics: Anti-Bacterial Agents; Bacteria; Cephalosporins; Clinical Trials as Topic; Drug Resistance, Bacterial; Europe; Humans; Latin America; Microbial Sensitivity Tests; North America; Respiratory Tract Infections; Skin Diseases, Bacterial	2009
Safety profile of cefditoren. A pooled analysis of data from clinical trials in community-acquired respiratory tract infections. Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia, 2009, Volume: 22, Issue:2 Topics: Amoxicillin-Potassium Clavulanate Combination; Anti-Bacterial Agents; Cephalosporins; Clinical Trials, Phase III as Topic; Community-Acquired Infections; Double-Blind Method; Female; Gastrointestinal Diseases; Humans; Male; Penicillins; Randomized Controlled Trials as Topic; Respiratory Tract Infections; Superinfection; Vaginitis	2009
[Cefditoren and community-acquired lower respiratory tract infections (corrected)]. Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia, 2009, Volume: 22, Issue:3 Topics: Adolescent; Adult; Anti-Bacterial Agents; Cephalosporins; Community-Acquired Infections; Drug Resistance, Bacterial; Haemophilus Infections; Haemophilus influenzae; Humans; Pneumococcal Infections; Respiratory Tract Infections; Streptococcus pneumoniae	2009
Cefditoren in upper and lower community-acquired respiratory tract infections. Drug design, development and therapy, 2011, Feb-09, Volume: 5 Topics: Animals; Anti-Bacterial Agents; Cephalosporins; Community-Acquired Infections; Drug Resistance, Bacterial; Humans; Respiratory Tract Infections	2011
The role of cefditoren in the treatment of lower community-acquired respiratory tract infections (LRTIs): from bacterial eradication to reduced lung inflammation and epithelial damage. European review for medical and pharmacological sciences, 2014, Volume: 18, Issue:3 Topics: Anti-Bacterial Agents; Cephalosporins; Community-Acquired Infections; Disease Eradication; Disease Progression; Dose-Response Relationship, Drug; Drug Resistance, Multiple, Bacterial; Humans; Microbial Sensitivity Tests; Pneumonia, Bacterial; Pulmonary Disease, Chronic Obstructive	2014
[Cefditoren: a reality for the treatment of community infections]. Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia, 2017, Volume: 30, Issue:6 Topics: Anti-Bacterial Agents; Cephalosporins; Community-Acquired Infections; Humans	2017
[Role of cefditoren in the treatment of community skin and soft tissue infections: revisiting the evidence]. Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia, 2021, Volume: 34, Issue:3 Topics: Anti-Bacterial Agents; Cephalosporins; Humans; Soft Tissue Infections	2021
Cefditoren: a clinical overview. The new microbiologica, 2023, Volume: 46, Issue:1 Topics: Anti-Bacterial Agents; Cephalosporins; Humans; Monobactams; Respiratory Tract Infections; Staphylococcus aureus	2023

Trials

9 trial(s) available for cephalosporin c and cefditoren

Article	Year
Randomized, double-blind, multicenter comparison of oral cefditoren 200 or 400 mg BID with either cefuroxime 250 mg BID or cefadroxil 500 mg BID for the treatment of uncomplicated skin and skin-structure infections. Clinical therapeutics, 2002, Volume: 24, Issue:7 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Cefadroxil; Cefuroxime; Cephalosporins; Child; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Skin Diseases, Infectious; Soft Tissue Infections; Treatment Outcome	2002
[Clinical isolates and treatment of acute otitis media]. The Japanese journal of antibiotics, 2001, Volume: 54 Suppl B Topics: Acute Disease; Adolescent; Adult; Aged; Cephalosporins; Child; Child, Preschool; Community-Acquired Infections; Drug Resistance, Bacterial; Female; Haemophilus Infections; Haemophilus influenzae; Humans; Infant; Male; Middle Aged; Otitis Media; Penicillin Resistance; Pneumococcal Infections; Streptococcus pneumoniae; Treatment Outcome	2001
[Eradication of bacteria in upper pharynx of children treated with antibiotics]. The Japanese journal of antibiotics, 2001, Volume: 54 Suppl B Topics: Amoxicillin; Cephalosporins; Child; Child, Preschool; Community-Acquired Infections; Haemophilus Infections; Haemophilus influenzae; Humans; Infant; Penicillin Resistance; Pharyngitis; Pharynx; Pneumococcal Infections; Streptococcus pneumoniae; Treatment Outcome	2001
[Mid term report of the CDTR clinical trial for PRSP and BLNAR infections]. The Japanese journal of antibiotics, 2001, Volume: 54 Suppl B Topics: Acute Disease; Ampicillin Resistance; beta-Lactamases; Cephalosporins; Child; Child, Preschool; Community-Acquired Infections; Haemophilus Infections; Haemophilus influenzae; Humans; Infant; Otitis Media; Penicillin Resistance; Pneumococcal Infections; Prospective Studies; Respiratory Tract Infections; Streptococcus pneumoniae; Treatment Outcome	2001
[Isolation of bacteria and treatment of patients with pneumococcal and Haemophilus influenzae infections]. The Japanese journal of antibiotics, 2001, Volume: 54 Suppl B Topics: Adolescent; Adult; Cephalosporins; Child; Child, Preschool; Community-Acquired Infections; Female; Haemophilus Infections; Haemophilus influenzae; Humans; Infant; Male; Middle Aged; Otorhinolaryngologic Diseases; Pneumococcal Infections; Streptococcus pneumoniae; Treatment Outcome	2001
[Efficacy and safety of twice-daily administration of CTDR]. The Japanese journal of antibiotics, 2001, Volume: 54 Suppl B Topics: Anti-Bacterial Agents; Cephalosporins; Child, Preschool; Community-Acquired Infections; Drug Resistance, Bacterial; Female; Haemophilus Infections; Haemophilus influenzae; Humans; Male; Patient Compliance; Pneumococcal Infections; Streptococcus pneumoniae; Treatment Outcome	2001
Use of population pharmacokinetic modeling and Monte Carlo simulation to describe the pharmacodynamic profile of cefditoren in plasma and epithelial lining fluid. Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:6 Topics: Adult; Aged; Anti-Bacterial Agents; Bronchoalveolar Lavage Fluid; Cephalosporins; Female; Humans; Male; Microbial Sensitivity Tests; Middle Aged; Models, Biological; Monte Carlo Method; Urea	2008
Pharmacokinetic/pharmacodynamic serum and urine profile of cefditoren following single-dose and multiple twice- and thrice-daily regimens in healthy volunteers: a phase I study. Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia, 2007, Volume: 20, Issue:1 Topics: Adolescent; Adult; Anti-Bacterial Agents; Area Under Curve; Cephalosporins; Diarrhea; Double-Blind Method; Half-Life; Humans; Male; Microbial Sensitivity Tests	2007
In vitro Activity of Cefditoren against Middle Ear Fluid Isolates from Costa Rican Children with Otitis Media. Chemotherapy, 2014, Volume: 60, Issue:4 Topics: Anti-Bacterial Agents; Cephalosporins; Child; Child, Preschool; Costa Rica; Drug Resistance, Multiple, Bacterial; Ear, Middle; Female; Humans; Male; Microbial Sensitivity Tests; Otitis Media; Streptococcus pneumoniae	2014

Other Studies

94 other study(ies) available for cephalosporin c and cefditoren

Article	Year
An in vitro characterization of cefditoren, a new oral cephalosporin. Drugs under experimental and clinical research, 1994, Volume: 20, Issue:4 Topics: Bacteria; beta-Lactamases; Blood Proteins; Cations; Cephalosporins; Culture Media; Humans; Hydrogen-Ion Concentration; Microbial Sensitivity Tests; Molecular Structure; Protein Binding	1994
In-vitro activity of cefditoren against clinical isolates of penicillin-susceptible and resistant strains of Streptococcus pneumoniae, Haemophilus influenzae and Neisseria meningitidis. The Journal of antimicrobial chemotherapy, 1996, Volume: 37, Issue:5 Topics: Animals; Anti-Bacterial Agents; Cefotaxime; Ceftriaxone; Cephalosporins; Haemophilus influenzae; Meropenem; Microbial Sensitivity Tests; Neisseria meningitidis; Penicillin Resistance; Serum Bactericidal Test; Streptococcus pneumoniae; Thienamycins	1996
Activities of RPR 106972 (a new oral streptogramin), cefditoren (a new oral cephalosporin), two new oxazolidinones (U-100592 and U-100766), and other oral and parenteral agents against 203 penicillin-susceptible and -resistant pneumococci. Antimicrobial agents and chemotherapy, 1996, Volume: 40, Issue:2 Topics: Acetamides; Amino Acid Sequence; Anti-Bacterial Agents; Cephalosporins; Linezolid; Microbial Sensitivity Tests; Molecular Sequence Data; Oxazoles; Oxazolidinones; Penicillin Resistance; Streptococcus pneumoniae; Virginiamycin	1996
Inoculum effect and bactericidal activity of cefditoren and other antibiotics against Streptococcus pneumoniae, Haemophilus influenzae, and Neisseria meningitidis. European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 1996, Volume: 15, Issue:9 Topics: Anti-Bacterial Agents; Cephalosporins; Culture Media; Dose-Response Relationship, Drug; Haemophilus influenzae; Humans; Microbial Sensitivity Tests; Neisseria meningitidis; Streptococcus pneumoniae	1996
Time-kill studies on susceptibility of nine penicillin-susceptible and -resistant pneumococci to cefditoren compared with nine other beta-lactams. The Journal of antimicrobial chemotherapy, 1997, Volume: 39, Issue:2 Topics: Anti-Bacterial Agents; Cephalosporins; Microbial Sensitivity Tests; Penicillin Resistance; Streptococcus pneumoniae	1997
In vitro and in vivo antibacterial activities of CS-834, a novel oral carbapenem. Antimicrobial agents and chemotherapy, 1997, Volume: 41, Issue:12 Topics: Administration, Oral; Animals; Bacterial Infections; Bacterial Proteins; beta-Lactamases; Carbapenems; Carrier Proteins; Cefmenoxime; Cefpodoxime; Ceftizoxime; Cephalosporins; Drug Stability; Hexosyltransferases; Imipenem; Mice; Microbial Sensitivity Tests; Muramoylpentapeptide Carboxypeptidase; Penicillin-Binding Proteins; Peptidyl Transferases; Pneumonia, Staphylococcal; Prodrugs; Thienamycins	1997
In vitro evaluation of a novel orally administered cephalosporin (Cefditoren) tested against 1249 recent clinical isolates of Haemophilus influenzae, Moraxella catarrhalis, and Streptococcus pneumoniae. Diagnostic microbiology and infectious disease, 1998, Volume: 31, Issue:4 Topics: Anti-Bacterial Agents; beta-Lactamases; Cephalosporins; Community-Acquired Infections; Haemophilus influenzae; Humans; Microbial Sensitivity Tests; Moraxella catarrhalis; Penicillin Resistance; Penicillins; Respiratory Tract Infections; Streptococcus pneumoniae	1998
Streptococci isolated from various skin lesions: the interaction with Staphylococcus aureus strains. Journal of dermatological science, 1999, Volume: 19, Issue:1 Topics: Ampicillin; Anti-Bacterial Agents; Anti-Infective Agents; Cephalosporins; Erythromycin; Fluoroquinolones; Fusidic Acid; Humans; Imipenem; Microbial Sensitivity Tests; Minocycline; Naphthyridines; Ofloxacin; Penicillins; Skin Diseases, Bacterial; Species Specificity; Streptococcal Infections; Streptococcus; Vancomycin	1999
Comparison of agar dilution, microdilution, E-test, and disk diffusion methods for testing activity of cefditoren against Streptococcus pneumoniae. Journal of clinical microbiology, 1999, Volume: 37, Issue:10 Topics: Cephalosporins; Diffusion; Microbial Sensitivity Tests; Streptococcus pneumoniae	1999
[In vitro antibacterial activity of faropenem, a novel oral penem antibiotic, against enterohemorrhagic Escherichia coli O157 strains]. The Japanese journal of antibiotics, 1999, Volume: 52, Issue:8 Topics: Amoxicillin; Ampicillin; Anti-Bacterial Agents; Bacterial Toxins; beta-Lactams; Cefdinir; Cephalosporins; Clarithromycin; Escherichia coli O157; Fosfomycin; Kanamycin; Lactams; Microbial Sensitivity Tests; Minocycline; Norfloxacin; Shiga Toxin 1	1999
[Investigation of the antibacterial activity of faropenem against Streptococcus pneumoniae]. The Japanese journal of antibiotics, 1999, Volume: 52, Issue:9 Topics: Anti-Bacterial Agents; beta-Lactams; Cefaclor; Cephalosporins; Drug Resistance, Microbial; Lactams; Penicillin G; Penicillin Resistance; Streptococcus pneumoniae	1999
[In vitro activity of faropenem against beta-lactamase producing clinical isolates]. The Japanese journal of antibiotics, 2000, Volume: 53, Issue:3 Topics: Anti-Bacterial Agents; Bacteria; beta-Lactamases; beta-Lactams; Cefdinir; Cephalosporins; Drug Resistance, Microbial; Humans; Lactams; Microbial Sensitivity Tests	2000
Antimicrobial activity and in vitro susceptibility test development for cefditoren against Haemophilus influenzae, Moraxella catarrhalis, and Streptococcus species. Diagnostic microbiology and infectious disease, 2000, Volume: 37, Issue:2 Topics: Cefaclor; Cefixime; Cephalosporins; Gram-Negative Bacterial Infections; Haemophilus Infections; Haemophilus influenzae; Humans; Microbial Sensitivity Tests; Moraxella catarrhalis; Penicillins; Streptococcal Infections; Streptococcus	2000
Cefditoren activity against nearly 1000 non-fastidious bacterial isolates and the development of in vitro susceptibility test methods. Diagnostic microbiology and infectious disease, 2000, Volume: 37, Issue:2 Topics: Cephalosporins; Enterobacteriaceae; Gram-Negative Bacteria; Gram-Positive Cocci; Humans; Microbial Sensitivity Tests	2000
In vitro study of the post-antibiotic effect and the bactericidal activity of Cefditoren and ten other oral antimicrobial agents against upper and lower respiratory tract pathogens. Diagnostic microbiology and infectious disease, 2000, Volume: 37, Issue:3 Topics: Anti-Bacterial Agents; Bacteria; Cephalosporins; Colony Count, Microbial; Drug Resistance, Microbial; Haemophilus influenzae; Humans; Microbial Sensitivity Tests; Moraxella catarrhalis; Respiratory Tract Infections; Streptococcus pneumoniae; Streptococcus pyogenes	2000
Susceptibility of Streptococcus pneumoniae and Haemophilus influenzae to cefditoren, and provisional interpretive criteria. Diagnostic microbiology and infectious disease, 2000, Volume: 37, Issue:4 Topics: Ampicillin; Anti-Infective Agents; Cefaclor; Cefotaxime; Cephalosporin Resistance; Cephalosporins; Haemophilus influenzae; Microbial Sensitivity Tests; Ofloxacin; Penicillins; Streptococcus pneumoniae	2000
[Antimicrobial susceptibility and serotypes of Streptococcus pneumoniae isolated from the patients with respiratory tract infections in Hokusetsu Area of Osaka]. The Japanese journal of antibiotics, 2000, Volume: 53, Issue:7 Topics: Anti-Bacterial Agents; Cefdinir; Cefpodoxime; Ceftizoxime; Cephalosporins; Child; Child, Preschool; Clindamycin; Erythromycin; Humans; Minocycline; Penicillin G; Penicillins; Respiratory Tract Infections; Serotyping; Streptococcus pneumoniae	2000
Determination of cefditoren (ME 1206) in the plasma of elderly patients with multiple diseases using high-performance liquid chromatography. Clinical laboratory, 2000, Volume: 46, Issue:9-10 Topics: Aged; Aged, 80 and over; Calibration; Cephalosporins; Chromatography, High Pressure Liquid; Drug Monitoring; Drug Therapy, Combination; Equipment Design; Humans; Reference Standards; Reproducibility of Results; Respiratory Tract Infections; Sensitivity and Specificity	2000
[The frequency of Streptococcus pneumoniae strains and sensitivity surveillance for several antibiotics in Gifu Prefecture]. The Japanese journal of antibiotics, 2000, Volume: 53, Issue:12 Topics: Amoxicillin; Anti-Bacterial Agents; Cefaclor; Cefdinir; Cefixime; Cefmenoxime; Cefpodoxime; Ceftizoxime; Cephalosporins; Ciprofloxacin; Clarithromycin; Clindamycin; Drug Resistance, Microbial; Fluoroquinolones; Humans; Imipenem; Japan; Levofloxacin; Meropenem; Microbial Sensitivity Tests; Minocycline; Naphthyridines; Ofloxacin; Penicillin G; Penicillins; Streptococcus pneumoniae; Thienamycins	2000
Quality control parameters for cefditoren susceptibility tests. Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases, 2001, Volume: 7, Issue:2 Topics: Bacteria; Cephalosporins; Escherichia coli; Haemophilus influenzae; Humans; Microbial Sensitivity Tests; Quality Control; Staphylococcus aureus; Streptococcus pneumoniae	2001
In vitro activity of cefditoren against clinical isolates of penicillin-susceptible and penicillin-intermediate strains of Streptococcus pneumoniae isolated in Germany, 1992-1998. The Journal of antimicrobial chemotherapy, 2001, Volume: 48, Issue:2 Topics: Cephalosporins; Germany; Humans; In Vitro Techniques; Microbial Sensitivity Tests; Penicillins; Respiratory Tract Infections; Streptococcal Infections; Streptococcus pneumoniae	2001
Oral prodrug enters cephalosporin market. American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 2001, Nov-01, Volume: 58, Issue:21 Topics: Administration, Oral; Bacterial Infections; Bronchitis; Cephalosporins; Drug Approval; Drug Interactions; Humans; Pharyngitis; Prodrugs; Skin Diseases, Bacterial; United States; United States Food and Drug Administration	2001
Activity of cefditoren against beta-lactamase-positive and -negative Haemophilus influenzae and Moraxella catarrhalis. Diagnostic microbiology and infectious disease, 2002, Volume: 42, Issue:1 Topics: beta-Lactamases; Cephalosporins; Haemophilus influenzae; Humans; Microbial Sensitivity Tests; Moraxella catarrhalis; Prospective Studies	2002
In vitro susceptibility of recent clinical isolates of pneumococci to the investigational cephalosporin cefditoren. Diagnostic microbiology and infectious disease, 2002, Volume: 42, Issue:1 Topics: Cephalosporins; Humans; Microbial Sensitivity Tests; Streptococcus pneumoniae	2002
Cefditoren (Spectracef)--a new cephalosporin. The Medical letter on drugs and therapeutics, 2002, Jan-21, Volume: 44, Issue:1122 Topics: Administration, Oral; Anti-Bacterial Agents; Bronchitis; Cephalosporins; Humans; Pharyngitis	2002
Activity of cefditoren against respiratory pathogens. The Journal of antimicrobial chemotherapy, 2002, Volume: 50, Issue:1 Topics: Cephalosporins; Drug Resistance, Bacterial; Haemophilus Infections; Haemophilus influenzae; Humans; Microbial Sensitivity Tests; Mutation; Penicillin Resistance; Pneumococcal Infections; Respiratory Tract Infections; Streptococcus pneumoniae; Structure-Activity Relationship	2002
[Antibacterial activity of cefpodoxime against clinical isolates in 2000 and 2001]. The Japanese journal of antibiotics, 2002, Volume: 55, Issue:6 Topics: Adolescent; Adult; Bacteria; Bacterial Infections; Cefaclor; Cefdinir; Cefpodoxime; Cefpodoxime Proxetil; Ceftizoxime; Cephalosporins; Child; Drug Resistance, Bacterial; Humans; Japan; Product Surveillance, Postmarketing; Time Factors	2002
[Epidemiological study on patients with pneumococcal respiratory tract infection in a Japanese health facility during the past year]. The Japanese journal of antibiotics, 2001, Volume: 54 Suppl B Topics: Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; beta-Lactams; Cephalosporins; Chronic Disease; Clarithromycin; Community-Acquired Infections; Drug Therapy, Combination; Female; Humans; Lactams; Male; Middle Aged; Ofloxacin; Pneumococcal Infections; Respiratory Tract Infections; Streptococcus pneumoniae; Time Factors	2001
[Therapy for children with acute pneumococcal otitis media in an outpatient clinic]. The Japanese journal of antibiotics, 2001, Volume: 54 Suppl B Topics: Acute Disease; Amoxicillin; Cephalosporins; Child, Preschool; Community-Acquired Infections; Humans; Infant; Middle Ear Ventilation; Otitis Media; Penicillin Resistance; Pneumococcal Infections; Recurrence; Retrospective Studies; Streptococcus pneumoniae; Treatment Outcome	2001
[High-dose cefditren therapy for children with acute otitis media that had Streptococcus pneumoniae and haemophilus influenzae isolated from the nasopharynx]. The Japanese journal of antibiotics, 2001, Volume: 54 Suppl B Topics: Acute Disease; Cephalosporins; Child; Child, Preschool; Community-Acquired Infections; Haemophilus Infections; Haemophilus influenzae; Humans; Infant; Nasopharynx; Otitis Media; Penicillin Resistance; Pneumococcal Infections; Pulse Therapy, Drug; Retrospective Studies; Severity of Illness Index; Streptococcus pneumoniae; Treatment Outcome	2001
[Bacteriological aspects in the mid term report of the CDTR clinical trial for PRSP and BLNAR infections]. The Japanese journal of antibiotics, 2001, Volume: 54 Suppl B Topics: Acute Disease; Ampicillin Resistance; beta-Lactamases; Cephalosporins; Child; Child, Preschool; Community-Acquired Infections; Drug Resistance, Bacterial; Haemophilus Infections; Haemophilus influenzae; Humans; Infant; Otitis Media; Penicillin Resistance; Pneumococcal Infections; Respiratory Tract Infections; Streptococcus pneumoniae	2001
[Comparative study on bacterial eradication rate and clinical efficacy of CDTR, CFPN, and FRPM for treatment of children with otitis media and lower respiratory tract infection due to Streptococcus pneumoniae and Haemophilus influenzae]. The Japanese journal of antibiotics, 2001, Volume: 54 Suppl B Topics: Ampicillin Resistance; Anti-Bacterial Agents; beta-Lactams; Cephalosporins; Child; Child, Preschool; Community-Acquired Infections; Haemophilus Infections; Haemophilus influenzae; Humans; Infant; Lactams; Otitis Media; Penicillin Resistance; Pneumococcal Infections; Respiratory Tract Infections; Retrospective Studies; Streptococcus pneumoniae; Treatment Outcome	2001
[Infant case of acute otitis media due to PISP not eradicated with double-dose of CDTR]. The Japanese journal of antibiotics, 2001, Volume: 54 Suppl B Topics: Cephalosporins; Community-Acquired Infections; Female; Haemophilus Infections; Haemophilus influenzae; Humans; Infant; Otitis Media with Effusion; Penicillin Resistance; Pneumococcal Infections; Streptococcus pneumoniae; Treatment Failure; Treatment Outcome	2001
[Mode of transmission and natural course of pneumococcal infection]. The Japanese journal of antibiotics, 2001, Volume: 54 Suppl B Topics: Age Factors; Cephalosporins; Child Day Care Centers; Community-Acquired Infections; Disease Transmission, Infectious; Humans; Infant; Nasopharynx; Penicillin Resistance; Pneumococcal Infections; Risk Factors; Streptococcus pneumoniae	2001
[Study on Streptococcus pneumoniae isolated from infants in widely-separated primary care facilities in Japan]. The Japanese journal of antibiotics, 2001, Volume: 54 Suppl B Topics: Anti-Bacterial Agents; beta-Lactams; Cephalosporins; Child Day Care Centers; Child, Preschool; Drug Resistance, Bacterial; Humans; Infant; Japan; Lactams; Otitis Media; Penicillin G; Serotyping; Siblings; Streptococcus pneumoniae	2001
In vitro activity of cefditoren against a special collection of clinical isolates of Streptococcus pneumoniae from Hungary. Acta microbiologica et immunologica Hungarica, 2003, Volume: 50, Issue:2-3 Topics: Adult; Cephalosporins; Child; Drug Resistance, Multiple, Bacterial; Humans; Hungary; In Vitro Techniques; Penicillin Resistance; Pneumococcal Infections; Pneumonia, Pneumococcal; Respiratory Tract Infections; Streptococcus pneumoniae	2003
[Susceptibility of major pathogens of acute pharyngitis and tonsillitis to levofloxacin and other oral antimicrobial drugs]. The Japanese journal of antibiotics, 2003, Volume: 56, Issue:3 Topics: Acute Disease; Ampicillin; Anti-Infective Agents; Azithromycin; Cefdinir; Cefpodoxime; Ceftizoxime; Cephalosporins; Clarithromycin; Enterobacteriaceae; Haemophilus influenzae; Humans; Levofloxacin; Ofloxacin; Penicillin G; Pharyngitis; Streptococcus pneumoniae; Streptococcus pyogenes; Tonsillitis	2003
Simultaneous intravenous and intramiddle-ear dosing to determine cefditoren influx and efflux clearances in middle ear fluid in freely moving chinchillas. Journal of pharmaceutical sciences, 2003, Volume: 92, Issue:10 Topics: Animals; Anti-Bacterial Agents; Area Under Curve; Biological Transport; Cephalosporins; Chinchilla; Disease Models, Animal; Ear, Middle; Injections, Intravenous; Instillation, Drug; Male; Microdialysis; Otitis Media; Time Factors	2003
Antimicrobial susceptibility of respiratory Haemophilus influenzae strains isolated from pediatric respiratory tract infections. Pediatrics international : official journal of the Japan Pediatric Society, 2004, Volume: 46, Issue:4 Topics: Amoxicillin; Ampicillin; Anti-Bacterial Agents; beta-Lactamases; Cefotaxime; Ceftriaxone; Cephalosporins; Child; Child, Preschool; Dose-Response Relationship, Drug; Drug Resistance, Bacterial; Female; Haemophilus Infections; Haemophilus influenzae; Humans; Infant; Male; Microbial Sensitivity Tests; Respiratory Tract Infections	2004
[Clinical effect of ceftriaxone and cefditoren administration against oral and genital gonococcal infection]. The Japanese journal of antibiotics, 2006, Volume: 59, Issue:1 Topics: Adolescent; Adult; Anti-Bacterial Agents; Ceftriaxone; Cephalosporins; Female; Gonorrhea; Humans; Mouth Diseases; Sex Work	2006
Quantification of the cephalosporin antibiotic cefditoren in human plasma by high-performance liquid chromatography. Arzneimittel-Forschung, 2006, Volume: 56, Issue:4 Topics: Calibration; Cephalosporins; Chromatography, High Pressure Liquid; Humans; Reproducibility of Results; Specimen Handling; Spectrophotometry, Ultraviolet; Therapeutic Equivalency	2006
In vitro activity of cefditoren: antimicrobial efficacy against major respiratory pathogens from Asian countries. International journal of antimicrobial agents, 2006, Volume: 28, Issue:1 Topics: Anti-Bacterial Agents; Asia; Cephalosporins; Haemophilus influenzae; Humans; Klebsiella pneumoniae; Microbial Sensitivity Tests; Moraxella catarrhalis; Respiratory System; Staphylococcus aureus	2006
[Comparative studies on activities of antimicrobial agents against causative organisms isolated from patients with urinary tract infections (2004). I. Susceptibility distribution]. The Japanese journal of antibiotics, 2006, Volume: 59, Issue:3 Topics: Aminoglycosides; Ampicillin; Anti-Infective Agents; Aztreonam; Cefixime; Cefozopran; Cefpirome; Cefpodoxime; Ceftizoxime; Cephalosporins; Dibekacin; Drug Resistance, Bacterial; Enterococcus faecalis; Escherichia coli; Gentamicins; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; Imipenem; Klebsiella pneumoniae; Meropenem; Microbial Sensitivity Tests; Proteus mirabilis; Pseudomonas aeruginosa; Quinolones; Serratia marcescens; Staphylococcus aureus; Thienamycins; Urinary Tract Infections; Vancomycin	2006
Activity of cefditoren against clinical isolates of Streptococcus pneumoniae showing non-susceptibility to penicillins, cephalosporins, macrolides, ketolides or quinolones. International journal of antimicrobial agents, 2007, Volume: 29, Issue:2 Topics: Anti-Bacterial Agents; Cephalosporins; Humans; Ketolides; Macrolides; Microbial Sensitivity Tests; Penicillins; Quinolones; Streptococcus pneumoniae	2007
[Relationship between protein binding and antimicrobial activities of antibiotics against Streptococcus pneumoniae and Haemophilus influenzae]. The Japanese journal of antibiotics, 2006, Volume: 59, Issue:5 Topics: Administration, Oral; Anti-Bacterial Agents; Carbapenems; Cephalosporins; Child; Haemophilus influenzae; Humans; Injections, Intravenous; Meropenem; Microbial Sensitivity Tests; Protein Binding; Streptococcus pneumoniae; Thienamycins	2006
[Influence of the displacement of protein binding by ibuprofen in the activity of a third-generation cephalosporin against Streptococcus pneumoniae]. Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia, 2006, Volume: 19, Issue:4 Topics: Anti-Bacterial Agents; beta-Lactam Resistance; Binding, Competitive; Blood Proteins; Cephalosporins; Drug Interactions; Drug Resistance; Humans; Ibuprofen; Microbial Sensitivity Tests; Protein Binding; Serum Albumin; Streptococcal Infections; Streptococcus pneumoniae	2006
In vitro susceptibility of Spanish isolates of Neisseria gonorrhoeae to cefditoren and five other antimicrobial agents. International journal of antimicrobial agents, 2007, Volume: 29, Issue:4 Topics: Anti-Bacterial Agents; Cephalosporins; Drug Resistance, Bacterial; Gonorrhea; Humans; Microbial Sensitivity Tests; Neisseria gonorrhoeae; Spain	2007
In vitro activities of oral cephem and telithromycin against clinical isolates of major respiratory pathogens in Japan. Journal of Korean medical science, 2007, Volume: 22, Issue:1 Topics: Administration, Oral; Cephalosporins; Haemophilus influenzae; Humans; Ketolides; Methicillin Resistance; Microbial Sensitivity Tests; Staphylococcus aureus; Streptococcus pneumoniae; Streptococcus pyogenes	2007
Are beta-lactam breakpoints adequate to define non-susceptibility for all Haemophilus influenzae resistance phenotypes from a pharmacodynamic point of view? The Journal of antimicrobial chemotherapy, 2007, Volume: 59, Issue:4 Topics: Amoxicillin-Potassium Clavulanate Combination; Ampicillin Resistance; Anti-Bacterial Agents; beta-Lactamases; beta-Lactams; Cefuroxime; Cephalosporins; Computer Simulation; Drug Resistance, Bacterial; Haemophilus influenzae; Half-Life; Kinetics; Microbial Sensitivity Tests; Phenotype	2007
Effects of human albumin and serum on the in vitro bactericidal activity of cefditoren against penicillin-resistant Streptococcus pneumoniae. The Journal of antimicrobial chemotherapy, 2007, Volume: 60, Issue:1 Topics: Anti-Bacterial Agents; Cephalosporins; Culture Media; Humans; Microbial Sensitivity Tests; Penicillin Resistance; Protein Binding; Serum; Serum Albumin; Streptococcus pneumoniae	2007
Influence of the beta-lactam resistance phenotype on the cefuroxime versus cefditoren susceptibility of Streptococcus pneumoniae and Haemophilus influenzae recovered from children with acute otitis media. The Journal of antimicrobial chemotherapy, 2007, Volume: 60, Issue:2 Topics: Acute Disease; Anti-Bacterial Agents; beta-Lactam Resistance; beta-Lactamases; Cefuroxime; Cephalosporins; Child; Haemophilus influenzae; Humans; Microbial Sensitivity Tests; Otitis Media; Phenotype; Streptococcus pneumoniae	2007
Pharmacodynamics of simulated total versus free-drug serum concentrations of a low versus a high protein bound third-generation oral cephalosporin (Cefpodoxime versus cefditoren) against Streptococcus pneumoniae. Journal of chemotherapy (Florence, Italy), 2007, Volume: 19, Issue:3 Topics: Anti-Bacterial Agents; Blood Proteins; Cefpodoxime; Ceftizoxime; Cephalosporins; Computer Simulation; Drug Resistance, Bacterial; Microbial Sensitivity Tests; Models, Biological; Protein Binding; Streptococcus pneumoniae	2007
In vitro activity of cefditoren against clinical isolates of Escherichia coli from a Korean hospital. International journal of antimicrobial agents, 2007, Volume: 30, Issue:3 Topics: Anti-Bacterial Agents; Cephalosporins; Cross Infection; Escherichia coli; Escherichia coli Infections; Humans; Korea; Microbial Sensitivity Tests	2007
influence of TEM-1 beta-lactamase on the pharmacodynamic activity of simulated total versus free-drug serum concentrations of cefditoren (400 milligrams) versus amoxicillin-clavulanic acid (2,000/125 milligrams) against Haemophilus influenzae strains exhi Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:10 Topics: Amoxicillin-Potassium Clavulanate Combination; Anti-Bacterial Agents; beta-Lactamases; Cephalosporins; Colony Count, Microbial; Genes, Bacterial; Haemophilus influenzae; Kinetics; Microbial Sensitivity Tests; Peptidoglycan Glycosyltransferase; Protein Binding; Spectrophotometry, Ultraviolet	2007
Crystal structure of cefditoren complexed with Streptococcus pneumoniae penicillin-binding protein 2X: structural basis for its high antimicrobial activity. Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:11 Topics: Bacterial Proteins; Binding Sites; Cephalosporins; Crystallography, X-Ray; Models, Molecular; Molecular Structure; Penicillin-Binding Proteins; Protein Binding; Protein Structure, Secondary; Protein Structure, Tertiary; Streptococcus pneumoniae	2007
Urine bactericidal activity against Escherichia coli isolates exhibiting different resistance phenotypes/genotypes in an in vitro pharmacodynamic model simulating urine concentrations obtained after oral administration of a 400-milligram single dose of ce Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:3 Topics: Amdinocillin Pivoxil; Anti-Bacterial Agents; Anti-Infective Agents, Urinary; beta-Lactamases; Cephalosporins; Escherichia coli; Escherichia coli Infections; Genotype; Humans; Microbial Sensitivity Tests; Models, Biological; Phenotype; Urinary Tract Infections; Urine	2008
Monte Carlo simulation describing the pharmacodynamic profile of cefditoren in plasma from healthy volunteers. International journal of antimicrobial agents, 2008, Volume: 31, Issue:4 Topics: Adult; Anti-Bacterial Agents; Cephalosporins; Computer Simulation; Endpoint Determination; Fasting; Humans; Male; Models, Statistical; Monte Carlo Method; Serum Bactericidal Test	2008
Antimicrobial susceptibility of Haemophilus influenzae and Moraxella catarrhalis isolates in eight Central, East and Baltic European countries in 2005-06: results of the Cefditoren Surveillance Study. The Journal of antimicrobial chemotherapy, 2008, Volume: 61, Issue:5 Topics: Anti-Bacterial Agents; Cephalosporins; Drug Resistance, Bacterial; Europe; Haemophilus influenzae; Humans; Microbial Sensitivity Tests; Moraxella catarrhalis	2008
Comparison of the efficacies of oral beta-lactams in selection of Haemophilus influenzae transformants with mutated ftsI genes. Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:5 Topics: Ampicillin; Bacterial Proteins; beta-Lactams; Carbapenems; Cefdinir; Cefprozil; Cephalosporins; Gene Transfer, Horizontal; Haemophilus influenzae; Mutation; Penicillin-Binding Proteins	2008
Antimicrobial activity of cefditoren tested against contemporary (2004-2006) isolates of Haemophilus influenzae and Moraxella catarrhalis responsible for community-acquired respiratory tract infections in the United States. Diagnostic microbiology and infectious disease, 2008, Volume: 61, Issue:2 Topics: Anti-Bacterial Agents; Cephalosporins; Community-Acquired Infections; Haemophilus influenzae; Humans; Microbial Sensitivity Tests; Moraxella catarrhalis; Respiratory Tract Infections; United States	2008
Efficacy of cefditoren in the treatment of upper respiratory tract infections: a pooled analysis of six clinical trials. Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia, 2008, Volume: 21, Issue:1 Topics: Anti-Bacterial Agents; Cephalosporins; Humans; Randomized Controlled Trials as Topic; Respiratory Tract Infections; Treatment Outcome	2008
Update of the activity of cefditoren and comparator oral beta-lactam agents tested against community-acquired Streptococcus pneumoniae isolates (USA, 2004-2006). Journal of chemotherapy (Florence, Italy), 2008, Volume: 20, Issue:2 Topics: Anti-Bacterial Agents; beta-Lactams; Cephalosporins; Community-Acquired Infections; Drug Resistance, Bacterial; Humans; Microbial Sensitivity Tests; Respiratory Tract Infections; Streptococcus pneumoniae	2008
High protein binding and cidal activity against penicillin-resistant S. pneumoniae: a cefditoren in vitro pharmacodynamic simulation. PloS one, 2008, Jul-23, Volume: 3, Issue:7 Topics: Albumins; Cephalosporins; Chemistry, Pharmaceutical; Computer Simulation; Humans; Kinetics; Microbial Sensitivity Tests; Penicillin Resistance; Penicillins; Protein Binding; Serum; Spectrophotometry, Ultraviolet; Streptococcus pneumoniae	2008
In vitro activity of cefditoren and other antimicrobial agents against 288 Streptococcus pneumoniae and 220 Haemophilus influenzae clinical strains isolated in Zaragoza, Spain. Diagnostic microbiology and infectious disease, 2008, Volume: 62, Issue:2 Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; Cephalosporins; Haemophilus Infections; Haemophilus influenzae; Humans; Microbial Sensitivity Tests; Middle Aged; Penicillin Resistance; Pneumococcal Infections; Pneumonia, Pneumococcal; Respiratory Tract Infections; Spain; Streptococcus pneumoniae	2008
Antibacterial activity of cefditoren against major community-acquired respiratory pathogens recently isolated in Italy. Journal of chemotherapy (Florence, Italy), 2008, Volume: 20, Issue:5 Topics: Anti-Bacterial Agents; Cephalosporins; Community-Acquired Infections; Haemophilus influenzae; Humans; Italy; Klebsiella pneumoniae; Microbial Sensitivity Tests; Moraxella catarrhalis; Respiratory Tract Infections; Streptococcus pneumoniae; Streptococcus pyogenes	2008
Influence of different resistance traits on the competitive growth of Haemophilus influenzae in antibiotic-free medium and selection of resistant populations by different {beta}-lactams: an in vitro pharmacodynamic approach. The Journal of antimicrobial chemotherapy, 2009, Volume: 63, Issue:6 Topics: Amoxicillin-Potassium Clavulanate Combination; Anti-Bacterial Agents; beta-Lactams; Cefuroxime; Cephalosporins; Coculture Techniques; Colony Count, Microbial; Haemophilus influenzae; Humans; Microbial Sensitivity Tests; Selection, Genetic	2009
PEPT1 involved in the uptake and transepithelial transport of cefditoren in vivo and in vitro. European journal of pharmacology, 2009, Jun-10, Volume: 612, Issue:1-3 Topics: Animals; Anti-Bacterial Agents; Biological Transport; Caco-2 Cells; Cephalosporins; Dipeptides; Dose-Response Relationship, Drug; Epithelial Cells; Humans; Hydrogen-Ion Concentration; Intestinal Absorption; Intestinal Mucosa; Intestine, Small; Jejunum; Kidney; Kinetics; Male; Membrane Transport Proteins; Molecular Structure; Peptide Transporter 1; Rats; Rats, Wistar; Symporters	2009
Cefditoren versus community-acquired respiratory pathogens: time-kill studies. Journal of chemotherapy (Florence, Italy), 2009, Volume: 21, Issue:4 Topics: Amoxicillin; Anti-Bacterial Agents; Bacteria; Cephalosporins; Colony Count, Microbial; Community-Acquired Infections; Humans; Microbial Sensitivity Tests; Respiratory Tract Infections; Time Factors; Treatment Outcome	2009
Comparative in vitro activity of cefditoren and other antimicrobials against Enterobacteriaceae causing community-acquired uncomplicated urinary tract infections in women: a Spanish nationwide multicenter study. Diagnostic microbiology and infectious disease, 2010, Volume: 67, Issue:3 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Automation; Cephalosporins; Child; Child, Preschool; Community-Acquired Infections; Enterobacteriaceae; Enterobacteriaceae Infections; Female; Humans; Infant; Microbial Sensitivity Tests; Middle Aged; Spain; Urinary Tract Infections; Young Adult	2010
Cefditoren versus ceftazidime in inducer-substrate combinations for the evaluation of AmpC production in a disc approximation test. Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia, 2010, Volume: 23, Issue:2 Topics: Anti-Bacterial Agents; Bacteria; Bacterial Infections; Bacterial Proteins; beta-Lactamases; Ceftazidime; Cephalosporins; Enterobacteriaceae; Humans; Imipenem; Microbial Sensitivity Tests; Species Specificity	2010
Antibiotic susceptibility of respiratory pathogens recently isolated in Italy: focus on cefditoren. Journal of chemotherapy (Florence, Italy), 2010, Volume: 22, Issue:3 Topics: Anti-Bacterial Agents; Cephalosporins; Community-Acquired Infections; Gram-Negative Bacteria; Gram-Negative Bacterial Infections; Humans; Italy; Microbial Sensitivity Tests; Respiratory Tract Infections	2010
Enhanced in vivo activity of cefditoren in pre-immunized mice against penicillin-resistant S. pneumoniae (serotypes 6B, 19F and 23F) in a sepsis model. PloS one, 2010, Aug-10, Volume: 5, Issue:8 Topics: Animals; Anti-Bacterial Agents; Antibodies, Bacterial; Antibody Specificity; Cephalosporins; Disease Models, Animal; Female; HL-60 Cells; Humans; Immunization; Immunization, Passive; Mice; Mice, Inbred BALB C; Microbial Sensitivity Tests; Penicillin Resistance; Phagocytes; Phagocytosis; Sepsis; Serotyping; Streptococcus pneumoniae; Vaccines, Inactivated	2010
Molecular mechanisms of biliary excretion of cefditoren and the effects of cefditoren on the expression levels of hepatic transporters. Drug metabolism and pharmacokinetics, 2010, Volume: 25, Issue:4 Topics: Animals; Anti-Bacterial Agents; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Bile; Cephalosporins; Drug Interactions; Liver; Male; Novobiocin; Organic Anion Transporters, Sodium-Independent; Probenecid; Rats; Rats, Wistar; RNA, Messenger; Verapamil	2010
In vitro antimicrobial activity of cefditoren and other oral antibiotics against Streptococcus pneumoniae, isolated from children with community acquired respiratory tract infections. The Japanese journal of antibiotics, 2010, Volume: 63, Issue:1 Topics: Acute Disease; Amoxicillin; Anti-Bacterial Agents; Cefaclor; Cefdinir; Cefuroxime; Cephalosporins; Child; Child, Preschool; Community-Acquired Infections; Drug Resistance, Bacterial; Humans; Korea; Respiratory Tract Infections; Streptococcus pneumoniae	2010
Efficacy of simulated cefditoren versus amoxicillin-clavulanate free concentrations in countering intrastrain ftsI gene diffusion in Haemophilus influenzae. Antimicrobial agents and chemotherapy, 2011, Volume: 55, Issue:6 Topics: Amoxicillin-Potassium Clavulanate Combination; Anti-Bacterial Agents; beta-Lactamases; Cephalosporins; Diffusion; Drug Resistance, Bacterial; Genes, Bacterial; Haemophilus influenzae; Humans; Microbial Sensitivity Tests	2011
In vitro activity of cefditoren and other comparators against Streptococcus pneumoniae, Haemophilus influenzae, and Moraxella catarrhalis causing community-acquired respiratory tract infections in China. Diagnostic microbiology and infectious disease, 2012, Volume: 73, Issue:2 Topics: Anti-Bacterial Agents; Cephalosporins; China; Community-Acquired Infections; Drug Resistance, Bacterial; Haemophilus influenzae; Humans; Microbial Sensitivity Tests; Moraxella catarrhalis; Respiratory Tract Infections; Streptococcus pneumoniae	2012
Cefditoren and ceftriaxone enhance complement-mediated immunity in the presence of specific antibodies against antibiotic-resistant pneumococcal strains. PloS one, 2012, Volume: 7, Issue:9 Topics: Acute-Phase Proteins; Animals; Anti-Bacterial Agents; Antibodies; beta-Lactams; Ceftriaxone; Cephalosporins; Complement Activation; Complement C1q; Complement C3c; Drug Resistance, Microbial; Egtazic Acid; Flow Cytometry; Humans; Immune System; Mice; Phagocytosis; Streptococcus pneumoniae	2012
Cefditoren: Comparative efficacy with other antimicrobials and risk factors for resistance in clinical isolates causing UTIs in outpatients. BMC infectious diseases, 2012, Sep-25, Volume: 12 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Cephalosporins; Drug Resistance, Bacterial; Enterobacteriaceae; Enterobacteriaceae Infections; Female; Greece; Humans; Male; Microbial Sensitivity Tests; Middle Aged; Outpatients; Pregnancy; Risk Factors; Treatment Outcome; Urinary Tract Infections; Young Adult	2012
[Morphological changes in penicillin-resistant Streptococcus pneumoniae and beta-lactamase-nonproducing, ampicillin-resistant Haemophilus influenzae after exposure to oral antibacterial agents]. The Japanese journal of antibiotics, 2012, Volume: 65, Issue:5 Topics: Amoxicillin; Ampicillin Resistance; Anti-Bacterial Agents; Bacteriolysis; beta-Lactamases; Carbapenems; Cephalosporins; Child; Dose-Response Relationship, Drug; Fluoroquinolones; Haemophilus Infections; Haemophilus influenzae; Humans; Microscopy, Phase-Contrast; Naphthyridines; Penicillin Resistance; Pneumococcal Infections; Streptococcus pneumoniae; Time Factors	2012
Correlation of antibiotic prophylaxis and difficulty of extraction with postoperative inflammatory complications in the lower third molar surgery. The British journal of oral & maxillofacial surgery, 2014, Volume: 52, Issue:1 Topics: Adolescent; Adult; Aged; Anesthesia, Dental; Anti-Bacterial Agents; Antibiotic Prophylaxis; Cephalosporins; Dry Socket; Female; Humans; Male; Mandible; Middle Aged; Molar, Third; Nerve Block; Osteotomy; Pain, Postoperative; Postoperative Complications; Retrospective Studies; Surgical Flaps; Surgical Wound Infection; Tooth Extraction; Trismus; Young Adult	2014
In vitro antibacterial activities of two novel oral antibiotics, tebipenem and cefditoren, and other comparators against community-acquired respiratory tract infection-associated bacterial pathogens: a multicentre study in China. International journal of antimicrobial agents, 2014, Volume: 43, Issue:1 Topics: Anti-Bacterial Agents; Bacteria; Bacterial Infections; Carbapenems; Cephalosporins; China; Community-Acquired Infections; Humans; Microbial Sensitivity Tests; Respiratory Tract Infections	2014
Population pharmacokinetics of cefditoren pivoxil in non-infected adults. The Japanese journal of antibiotics, 2014, Volume: 67, Issue:1 Topics: Administration, Oral; Adult; Anti-Bacterial Agents; Biological Availability; Cephalosporins; Female; Humans; Male; Models, Biological	2014
[Cerebellar syndrome induced by metronidazole: a rare side effect]. Revista de neurologia, 2016, Apr-01, Volume: 62, Issue:7 Topics: Anti-Bacterial Agents; Brain Abscess; Cefotaxime; Cephalosporins; Cerebellar Ataxia; Diagnosis, Differential; Diverticulitis; Drug Therapy, Combination; Dysarthria; Humans; Linezolid; Liver Abscess; Lung Abscess; Magnetic Resonance Angiography; Male; Metronidazole; Middle Aged; Paraneoplastic Syndromes; Vasculitis	2016
The most appropriate therapeutic strategy for acute lower respiratory tract infections: a Delphi-based approach. Journal of chemotherapy (Florence, Italy), 2017, Volume: 29, Issue:5 Topics: Anti-Bacterial Agents; Cephalosporins; Drug Resistance, Bacterial; Evidence-Based Medicine; Humans; Inappropriate Prescribing; Respiratory Tract Infections	2017
Pharmacokinetic changes of cefdinir and cefditoren and its molecular mechanisms in acute kidney injury in rats. The Journal of pharmacy and pharmacology, 2018, Volume: 70, Issue:11 Topics: Acute Kidney Injury; Animals; Anti-Bacterial Agents; Cefdinir; Cephalosporins; Cisplatin; Disease Models, Animal; Gene Expression Regulation; Kidney; Male; Organic Anion Transport Protein 1; Organic Anion Transporters, Sodium-Independent; Rats, Wistar; Renal Elimination	2018
Genetic characteristics and antibiotic resistance of Haemophilus influenzae isolates from pediatric patients with acute otitis media after introduction of 13-valent pneumococcal conjugate vaccine in Japan. Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy, 2019, Volume: 25, Issue:9 Topics: Acute Disease; Ampicillin; Anti-Bacterial Agents; beta-Lactam Resistance; Carbapenems; Cephalosporins; Child, Preschool; Drug Resistance, Multiple, Bacterial; Fluoroquinolones; Haemophilus Infections; Haemophilus influenzae; Humans; Infant; Japan; Microbial Sensitivity Tests; Multilocus Sequence Typing; Naphthyridines; Otitis Media; Pneumococcal Vaccines; Quinolones; Streptococcus pneumoniae; Vaccines, Conjugate	2019
Abrogation of lysophosphatidic acid receptor 1 ameliorates murine vasculitis. Arthritis research & therapy, 2019, 08-20, Volume: 21, Issue:1 Topics: Animals; Cell Movement; Cephalosporins; Chemokine CXCL1; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Humans; Immunohistochemistry; Interleukin-8; Male; Mice; Mice, Inbred C57BL; Neutrophils; Receptors, Lysophosphatidic Acid; Signal Transduction; Vasculitis	2019
Clinical efficacy of amoxicillin/clavulanate plus cefditoren as de-escalation combination therapy for endocarditis due to strongly biofilm-forming Infectious diseases (London, England), 2020, Volume: 52, Issue:5 Topics: Aged; Amoxicillin-Potassium Clavulanate Combination; Anti-Bacterial Agents; Biofilms; Cephalosporins; Drug Therapy, Combination; Endocarditis, Bacterial; Enterococcus faecalis; Female; Humans; Length of Stay; Male; Middle Aged; Treatment Outcome	2020
A case of cefditoren-induced acute generalized exanthematous pustulosis during COVID-19 pandemics. Severe cutaneous adverse reactions are an issue. Journal of the European Academy of Dermatology and Venereology : JEADV, 2020, Volume: 34, Issue:10 Topics: Acute Generalized Exanthematous Pustulosis; Adrenal Cortex Hormones; Biopsy, Needle; Cephalosporins; Clinical Laboratory Techniques; Coronavirus Infections; COVID-19; COVID-19 Testing; Diagnosis, Differential; Female; Follow-Up Studies; Humans; Immunohistochemistry; Middle Aged; Obesity, Morbid; Pandemics; Pneumonia, Viral; Severe Acute Respiratory Syndrome; Severity of Illness Index; Treatment Outcome	2020
A national longitudinal study evaluating the activity of cefditoren and other antibiotics against non-susceptible Streptococcus pneumoniae strains during the period 2004-20 in Spain. The Journal of antimicrobial chemotherapy, 2022, 03-31, Volume: 77, Issue:4 Topics: Anti-Bacterial Agents; Cephalosporins; Humans; Longitudinal Studies; Microbial Sensitivity Tests; Pneumococcal Infections; Spain; Streptococcus pneumoniae	2022
Cefditoren-induced hepatitis. Revista espanola de enfermedades digestivas, 2022, Volume: 114, Issue:9 Topics: Anti-Bacterial Agents; Cephalosporins; Chemical and Drug Induced Liver Injury; Female; Hepatitis; Humans; Microbial Sensitivity Tests	2022
T405, a New Penem, Exhibits Antimicrobial agents and chemotherapy, 2022, 06-21, Volume: 66, Issue:6 Topics: Animals; Anti-Bacterial Agents; beta-Lactams; Cephalosporins; Humans; Imipenem; Meropenem; Mice; Microbial Sensitivity Tests; Mycobacterium Infections, Nontuberculous	2022
Effect of pneumococcal conjugate vaccines and SARS-CoV-2 on antimicrobial resistance and the emergence of Streptococcus pneumoniae serotypes with reduced susceptibility in Spain, 2004-20: a national surveillance study. The Lancet. Microbe, 2022, Volume: 3, Issue:10 Topics: Anti-Bacterial Agents; beta-Lactams; Cefotaxime; Cephalosporins; COVID-19 Drug Treatment; Drug Resistance, Bacterial; Erythromycin; Humans; Pandemics; Penicillins; Pneumococcal Infections; Pneumococcal Vaccines; SARS-CoV-2; Serogroup; Spain; Streptococcus pneumoniae; Vaccines, Conjugate	2022
Combination of Cefditoren and Microbiology spectrum, 2022, 12-21, Volume: 10, Issue:6 Topics: Acetylcysteine; Animals; Anti-Bacterial Agents; Antioxidants; Biofilms; Cephalosporins; COVID-19; Humans; Mice; Respiratory Tract Infections; SARS-CoV-2; Streptococcus pneumoniae	2022