cephalosporin c has been researched along with 7-aminodesacetoxycephalosporanic acid in 35 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (17.14) | 18.7374 |
| 1990's | 6 (17.14) | 18.2507 |
| 2000's | 16 (45.71) | 29.6817 |
| 2010's | 4 (11.43) | 24.3611 |
| 2020's | 3 (8.57) | 2.80 |
| Authors | Studies |
|---|---|
| Elizarovskaia, LM; Nys, PS; Savitskaia, EM; Shellenberg, NN | 1 |
| Kol'tsova, EV; Levitov, MM; Nys, PS; Savitskaia, EM; Shellenberg, NN | 1 |
| Lee, SH; Liu, YT | 1 |
| Han, WZ; Kou, XF; Wang, ZX; Zhang, QX | 1 |
| Navashin, SM; Rozenfel'd, GS | 1 |
| Chiba, K; Hirose, T; Mishio, S; Nakano, J; Uno, H | 1 |
| Bartoshevich, IuE; Nys, PS | 1 |
| Maladkar, NK | 1 |
| Demain, A | 1 |
| Conder, MJ; Crawford, L; McAda, PC; Rambosek, JA; Reeves, CD; Stepan, AM; Vinci, VA | 1 |
| Angel Moreno, M; Barredo, JL; Díez, B; Luis Adrio, J; Soler, G; Velasco, J | 1 |
| DeVroom, E; Janssen, AE; Kroon, PJ; Schroën, CG; Tramper, J; VandeWiel, S | 1 |
| Beeftink, HH; Bosma, R; Hoogschagen, MJ; Janssen, AE; Kroon, PJ; Moody, HM; Nierstrasz, VA; Schroën, CG; Tramper, J | 1 |
| Baldwin, JE; Dubus, A; Frere, JM; Lee, HJ; Lloyd, MD; Schofield, CJ | 1 |
| Bencivenga, U; De Luca, P; De Maio, A; Durante, D; Mita, DG; Schroën, CG; Travascio, P; Zito, E | 1 |
| Sheldon, RA; van Langen, LM; van Rantwijk, F; Wegman, MA | 1 |
| Beeftink, HH; Bosma, R; DeVroom, E; Janssen, AE; Kroon, PJ; Moody, HM; Nierstrasz, VA; Schroën, CG; Tjeerdsma, PS; Tramper, J; VanderLaan, JM | 1 |
| Chilov, GG; Shcherbakova, TA; Svedas, VK; Youshko, MI | 1 |
| Bai, X; Cui, F; Shi, J | 1 |
| Bruheim, P; Nielsen, J; Nielsen, ML; Noorman, H; Robin, J | 1 |
| Lettier, G; McIntyre, M; Nielsen, J; Noorman, H; Robin, J | 1 |
| Alkema, WB; de Vries, E; Floris, R; Janssen, DB | 1 |
| Wei, DZ; Yang, L | 1 |
| HOOVER, JR; STEDMAN, RJ; SWERED, K | 1 |
| Cool, RH; Otten, LG; Quax, WJ; Sio, CF | 1 |
| Boosten, WH; Bukhanov, AL; Moody, HM; Svedas, VK; Youshko, MI | 1 |
| Wei, DZ; Zhang, YW | 1 |
| Saravanane, R; Sundararaman, S | 1 |
| Rajesh, R; Saravanane, R; Sivacoumar, R; Tamijevendane, S | 1 |
| Fu, J; Lin, B; Tao, Y; Xu, Y; Zhao, J | 1 |
| Fan, K; Ji, J; Lin, B; Tao, Y; Wu, L; Yang, K; Zhao, J | 1 |
| Fan, K; Lin, B; Tao, Y; Yang, K | 1 |
| Fan, Y; Li, Y; Liu, Q | 2 |
| Bommarius, AS; Grover, MA; Harris, PR; Rousseau, RW | 1 |
3 review(s) available for cephalosporin c and 7-aminodesacetoxycephalosporanic acid
| Article | Year |
|---|---|
[Achievements in the field of obtaining and studying new semisynthetic cephalosporin antibiotics. Research in the field of directed cephalosporin synthesis].
Topics: Acylation; Cefotaxime; Cephalosporins; Cephamycins; Chemical Phenomena; Chemistry; Heterocyclic Compounds; Methods; Research; Structure-Activity Relationship | 1981 |
[Role of biocatalysis in the creation and improvement of production of beta-lactam antibiotics in Russia].
Topics: Anti-Bacterial Agents; Catalysis; Cephalosporins; Enzymes, Immobilized; Penicillanic Acid; Russia; Technology, Pharmaceutical | 1994 |
Engineering deacetoxycephalosporin C synthase as a catalyst for the bioconversion of penicillins.
Topics: Biocatalysis; Cephalosporins; Escherichia coli; Penicillin G; Penicillins; Substrate Specificity | 2017 |
32 other study(ies) available for cephalosporin c and 7-aminodesacetoxycephalosporanic acid
| Article | Year |
|---|---|
[Solubility and the complex-forming properties of the zwitterlytes, 6-aminopenicillanic and 7-aminodesacetoxycephalosporanic acids].
Topics: Cephalosporins; Chelating Agents; Chemical Phenomena; Chemistry, Physical; Drug Interactions; Hydrogen-Ion Concentration; Ions; Mathematics; Penicillanic Acid; Penicillin G; Solubility | 1979 |
[Physico-chemical properties of 7-aminodesacetoxycephalosporanic acid].
Topics: Cephalosporins; Colorimetry; Spectrophotometry | 1976 |
Production of cephalexin by Gluconobacter oxydans CCRC 10383.
Topics: Acetobacter; Acetobacteraceae; Cephalexin; Cephalosporins; Glycine; Pseudomonas putida; Xanthomonas | 1992 |
[Enzymatic synthesis of cefadroxil by E. coli PN-66].
Topics: Amidohydrolases; Cefadroxil; Cephalosporins; Escherichia coli; Hydrogen-Ion Concentration; Penicillin Amidase; Temperature | 1985 |
[Desulfurization of 7-aminodeacetoxycephalosporanic acid].
Topics: Anti-Bacterial Agents; Bacteria; Cephalosporins; Chemical Phenomena; Chemistry; Drug Resistance, Microbial; Oxidation-Reduction; Structure-Activity Relationship | 1984 |
Enzymatic production of cephalexin.
Topics: Acylation; Biotechnology; Cephalexin; Cephalosporins; Enzymes, Immobilized; Escherichia coli; Glycine; Hydrogen-Ion Concentration; In Vitro Techniques; Kinetics; Penicillin Amidase; Temperature | 1994 |
Enzymatic 7-ADCA: I said it couldn't be done.
Topics: Cephalosporins; Intramolecular Transferases; Penicillin-Binding Proteins; Penicillium chrysogenum; Recombinant Proteins | 1995 |
Production of cephalosporin intermediates by feeding adipic acid to recombinant Penicillium chrysogenum strains expressing ring expansion activity.
Topics: Acetyltransferases; Adipates; Cephalosporins; Culture Media; Gene Expression; Gene Transfer Techniques; Intramolecular Transferases; Oxygenases; Penicillin-Binding Proteins; Penicillium chrysogenum; Plasmids; Recombinant Proteins | 1995 |
Environmentally safe production of 7-aminodeacetoxycephalosporanic acid (7-ADCA) using recombinant strains of Acremonium chrysogenum.
Topics: Acremonium; Cephalosporins; Chromatography, High Pressure Liquid; Fermentation; Genes, Fungal; Mass Spectrometry; Plasmids; Recombination, Genetic | 2000 |
Equilibrium position, kinetics, and reactor concepts for the adipyl-7-ADCA-hydrolysis process.
Topics: Adipates; Amidohydrolases; Cephalosporins; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Hydrogen-Ion Concentration; Hydrolysis; Kinetics; Models, Chemical; Models, Theoretical; Penicillin Amidase; Temperature; Water | 2000 |
Modeling of the enzymatic kinetic synthesis of cephalexin--influence of substrate concentration and temperature.
Topics: Cephalexin; Cephalosporins; Enzymes; Kinetics; Models, Chemical; Substrate Specificity; Temperature | 2001 |
Probing the penicillin sidechain selectivity of recombinant deacetoxycephalosporin C synthase.
Topics: Amoxicillin; Ampicillin; Ascorbic Acid; Carbon Dioxide; Cephalexin; Cephalosporins; Chromatography, High Pressure Liquid; Coenzymes; Intramolecular Transferases; Iron; Ketoglutaric Acids; Kinetics; Oxygen; Penicillin G; Penicillin V; Penicillin-Binding Proteins; Penicillins; Recombinant Proteins; Reducing Agents; Spectrophotometry; Streptomyces; Substrate Specificity; Thermodynamics | 2001 |
Advantages of using non-isothermal bioreactors for the enzymatic synthesis of antibiotics: the penicillin G acylase as enzyme model.
Topics: Anti-Bacterial Agents; Bioreactors; Catalysis; Cephalexin; Cephalosporins; Coated Materials, Biocompatible; Enzymes, Immobilized; Equipment Design; Escherichia coli; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Membranes, Artificial; Methacrylates; Models, Chemical; Nylons; Penicillin Amidase; Propylene Glycols; Sensitivity and Specificity; Temperature | 2002 |
A two-step, one-pot enzymatic synthesis of cephalexin from D-phenylglycine nitrile.
Topics: Acetonitriles; Catalysis; Cephalexin; Cephalosporins; Escherichia coli; Glycine; Hydro-Lyases; Models, Chemical; Multienzyme Complexes; Penicillin Amidase; Quality Control; Rhodococcus; Sensitivity and Specificity | 2002 |
Integrated reactor concepts for the enzymatic kinetic synthesis of cephalexin.
Topics: Adsorption; Cephalexin; Cephalosporins; Chelating Agents; Combinatorial Chemistry Techniques; Enzymes, Immobilized; Escherichia coli; Hydrogen-Ion Concentration; Hydrolysis; Multienzyme Complexes; Naphthols; Penicillin Amidase; Polystyrenes; Quality Control; Resins, Synthetic; Sensitivity and Specificity | 2002 |
Quantitative characterization of the nucleophile reactivity in penicillin acylase-catalyzed acyl transfer reactions.
Topics: Catalysis; Cephalosporins; Penicillanic Acid; Penicillin Amidase; Substrate Specificity | 2002 |
[Enzymatic synthesis of cephradine].
Topics: Bacillus megaterium; Cephalosporins; Cephradine; Enzymes, Immobilized; Penicillin Amidase | 1998 |
Continuous cultivations of a Penicillium chrysogenum strain expressing the expandase gene from Streptomyces clavuligerus: Kinetics of adipoyl-7-aminodeacetoxycephalosporanic acid and byproduct formations.
Topics: Bioreactors; Cell Culture Techniques; Cephalosporins; Intramolecular Transferases; Kinetics; Lactams; Penicillin-Binding Proteins; Penicillium chrysogenum; Recombinant Proteins; Species Specificity; Streptomyces | 2003 |
Continuous cultivations of a Penicillium chrysogenum strain expressing the expandase gene from Streptomyces clavuligerus: Growth yields and morphological characterization.
Topics: Adipates; Bioreactors; Cell Culture Techniques; Cell Size; Cephalosporins; Glucose; Kinetics; Lactams; Models, Biological; Mycelium; Penicillium chrysogenum; Recombinant Proteins; Species Specificity; Streptomyces | 2003 |
Kinetics of enzyme acylation and deacylation in the penicillin acylase-catalyzed synthesis of beta-lactam antibiotics.
Topics: Acylation; Anti-Bacterial Agents; Binding Sites; Binding, Competitive; Catalysis; Cephalosporins; Deuterium; Escherichia coli; Glycine; Hydrolysis; Kinetics; Penicillanic Acid; Penicillin Amidase; Phenylacetates; Protons; Spectrophotometry, Ultraviolet; Substrate Specificity | 2003 |
Enhanced enzymatic synthesis of a semi-synthetic cephalosprin, cefaclor, with in situ product removal.
Topics: Bioreactors; Cefaclor; Cephalosporins; Chromatography, High Pressure Liquid; Enzymes, Immobilized; Glycine; Hydrogen-Ion Concentration; Hydrolysis; Models, Chemical; Penicillin Amidase; Spectrophotometry; Substrate Specificity | 2003 |
7-AMINODESACETOXYCEPHALOSPORANIC ACID AND ITS DERIVATIVES.
Topics: Anti-Bacterial Agents; Cephalosporins; Chemistry, Pharmaceutical; Escherichia coli; Klebsiella; Penicillins; Pharmacology; Proteus; Research; Salmonella typhimurium; Staphylococcus; Streptococcus pyogenes | 1964 |
Analysis of a substrate specificity switch residue of cephalosporin acylase.
Topics: Adipates; Amino Acid Sequence; Cephalosporins; Dinucleoside Phosphates; Enzyme Activation; Hydrolysis; Molecular Sequence Data; Mutagenesis, Site-Directed; Penicillin Amidase; Protein Engineering; Protein Structure, Tertiary; Pseudomonas; Recombinant Proteins; Structure-Activity Relationship; Substrate Specificity | 2003 |
Penicillin acylase-catalyzed synthesis of beta-lactam antibiotics in highly condensed aqueous systems: beneficial impact of kinetic substrate supersaturation.
Topics: Amoxicillin; Ampicillin; Anti-Bacterial Agents; beta-Lactams; Catalysis; Cephalexin; Cephalosporins; Enzyme Activation; Escherichia coli; Kinetics; Penicillanic Acid; Penicillin Amidase; Solutions; Substrate Specificity; Water | 2004 |
Enzymatic preparation of cefaclor with immobilized penicillin acylase.
Topics: Alcaligenes; Catalysis; Cephalosporins; Enzymes, Immobilized; Penicillins; Piperidines | 2008 |
Effect of loading rate and HRT on the removal of cephalosporin and their intermediates during the operation of a membrane bioreactor treating pharmaceutical wastewater.
Topics: Anaerobiosis; Anti-Bacterial Agents; Bioreactors; Cephalexin; Cephalosporins; Drug Industry; Equipment Reuse; Industrial Waste; Membranes, Artificial; Waste Disposal, Fluid; Water Pollutants, Chemical; Water Purification | 2009 |
Anaerobic stabilization and conversion of transformed intermediates of antibiotic pharmaceutical effluent in a fluidized bed reactor.
Topics: Aerobiosis; Anaerobiosis; Anti-Bacterial Agents; Biodegradation, Environmental; Bioreactors; Cephalexin; Cephalosporins; Hydrogen-Ion Concentration; India; Industrial Waste; Pharmaceutical Preparations; Phenylacetates; Sewage; Temperature; Waste Disposal, Fluid; Waste Management | 2011 |
[Optimization of whole-cell biocatalysis for phenylacetyl- 7-aminodeacetoxycephalosporanic acid production].
Topics: Anti-Bacterial Agents; Biocatalysis; Cephalosporins; Escherichia coli; Metabolic Engineering | 2014 |
Reconstitution of TCA cycle with DAOCS to engineer Escherichia coli into an efficient whole cell catalyst of penicillin G.
Topics: Acetates; Biocatalysis; Cephalosporins; Citric Acid Cycle; Escherichia coli; Gene Knockout Techniques; Genes, Bacterial; Glucose; Glyoxylates; Intramolecular Transferases; Metabolic Engineering; Mutation; Penicillin G; Penicillin-Binding Proteins; Streptomyces; Time Factors | 2015 |
Efficient enzymatic synthesis of cephalexin in suspension aqueous solution system.
Topics: Catalysis; Cephalexin; Cephalosporins; Enzymes, Immobilized; Escherichia coli; Escherichia coli Proteins; Glycine; Penicillin Amidase | 2021 |
Enhanced Dissolution of 7-ADCA in the Presence of PGME for Enzymatic Synthesis of Cephalexin.
Topics: Cephalexin; Cephalosporins; Enzymes, Immobilized; Glycine; Penicillin Amidase; Propylene Glycols; Solubility; Temperature | 2022 |
Selectivity and kinetic modeling of penicillin G acylase variants for the synthesis of cephalexin under a broad range of substrate concentrations.
Topics: beta-Lactams; Cephalexin; Cephalosporins; Kinetics; Penicillin Amidase; Propylene Glycols | 2022 |