Page last updated: 2024-08-23

cephalexin and valacyclovir

cephalexin has been researched along with valacyclovir in 11 studies

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (9.09)18.2507
2000's4 (36.36)29.6817
2010's5 (45.45)24.3611
2020's1 (9.09)2.80

Authors

AuthorsStudies
Balimane, PV; Guo, A; Hu, P; Leibach, FH; Sinko, PJ1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Benet, LZ; Brouwer, KL; Chu, X; Dahlin, A; Evers, R; Fischer, V; Giacomini, KM; Hillgren, KM; Hoffmaster, KA; Huang, SM; Ishikawa, T; Keppler, D; Kim, RB; Lee, CA; Niemi, M; Polli, JW; Sugiyama, Y; Swaan, PW; Tweedie, DJ; Ware, JA; Wright, SH; Yee, SW; Zamek-Gliszczynski, MJ; Zhang, L1
Avdeef, A; Tam, KY1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Amidon, GL; Chu, X; Fleisher, D; Komorowski, TE; Landowski, CP; Sun, D; Wallsten, R1
Anderle, P; Chin-Hong, P; Guglielmo, BJ; Lin, ET; Phan, DD; Sadee, W1
Bado, A; Beaufils, B; Buyse, M; Farinotti, R; Hindlet, P; Radeva, G; Walker, F1
Bayart, C; Brandling-Bennett, H; Yang, S1
Liang, LM; Liu, L; Liu, PH; Liu, XD; Qin, L; Xu, F; Zhou, JJ1

Reviews

2 review(s) available for cephalexin and valacyclovir

ArticleYear
Membrane transporters in drug development.
    Nature reviews. Drug discovery, 2010, Volume: 9, Issue:3

    Topics: Animals; Computer Simulation; Decision Trees; Drug Approval; Drug Discovery; Drug Evaluation, Preclinical; Drug Interactions; Humans; Membrane Transport Proteins; Mice; Mice, Knockout; Prescription Drugs

2010
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Trials

1 trial(s) available for cephalexin and valacyclovir

ArticleYear
Intra- and interindividual variabilities of valacyclovir oral bioavailability and effect of coadministration of an hPEPT1 inhibitor.
    Antimicrobial agents and chemotherapy, 2003, Volume: 47, Issue:7

    Topics: Acyclovir; Administration, Oral; Anti-Bacterial Agents; Antiviral Agents; Carrier Proteins; Cephalexin; Drug Interactions; Female; Humans; Male; Peptide Transporter 1; Symporters; Valacyclovir; Valine

2003

Other Studies

8 other study(ies) available for cephalexin and valacyclovir

ArticleYear
Interactions of a nonpeptidic drug, valacyclovir, with the human intestinal peptide transporter (hPEPT1) expressed in a mammalian cell line.
    The Journal of pharmacology and experimental therapeutics, 1999, Volume: 289, Issue:1

    Topics: Acyclovir; Animals; Anti-Bacterial Agents; Antiviral Agents; Biological Transport; Caco-2 Cells; Carrier Proteins; CHO Cells; Cricetinae; Dipeptides; Humans; Hydrogen-Ion Concentration; Kinetics; Lactams; Peptide Transporter 1; Rabbits; Rats; Symporters; Transfection; Valacyclovir; Valine

1999
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
How well can the Caco-2/Madin-Darby canine kidney models predict effective human jejunal permeability?
    Journal of medicinal chemistry, 2010, May-13, Volume: 53, Issue:9

    Topics: Animals; Disease Models, Animal; Dogs; Humans; Jejunal Diseases; Kidney Diseases; Models, Biological; Permeability; Porosity; Regression Analysis

2010
QSAR-based permeability model for drug-like compounds.
    Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8

    Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2011
Drug inhibition of Gly-Sar uptake and hPepT1 localization using hPepT1-GFP fusion protein.
    AAPS pharmSci, 2001, Volume: 3, Issue:1

    Topics: Acyclovir; Blotting, Western; Caco-2 Cells; Carrier Proteins; Cell Membrane; Cephalexin; Depression, Chemical; Dipeptides; Green Fluorescent Proteins; HeLa Cells; Humans; Luminescent Proteins; Microscopy, Confocal; Peptide Transporter 1; Recombinant Fusion Proteins; Subcellular Fractions; Symporters; Transfection; Valacyclovir; Valine

2001
Regulation of the oligopeptide transporter, PEPT-1, in DSS-induced rat colitis.
    Digestive diseases and sciences, 2007, Volume: 52, Issue:7

    Topics: Acyclovir; Animals; Anti-Bacterial Agents; Antiviral Agents; Biological Availability; Cephalexin; Colitis; Immunohistochemistry; Intestinal Mucosa; Male; Peptide Transporter 1; Rats; Rats, Wistar; RNA, Messenger; Symporters; Valacyclovir; Valine

2007
An atypical presentation of herpes simplex virus infection in Harlequin ichthyosis.
    Pediatric dermatology, 2018, Volume: 35, Issue:6

    Topics: Acyclovir; Anti-Bacterial Agents; Antiviral Agents; Cephalexin; Female; Herpes Simplex; Herpesvirus 1, Human; Humans; Ichthyosis, Lamellar; Infant; Valacyclovir; Valine

2018
Diabetes downregulates peptide transporter 1 in the rat jejunum: possible involvement of cholate-induced FXR activation.
    Acta pharmacologica Sinica, 2020, Volume: 41, Issue:11

    Topics: Animals; Caco-2 Cells; Cephalexin; Cholic Acids; Diabetes Mellitus, Experimental; Down-Regulation; Humans; Jejunum; Peptide Transporter 1; Rats; Receptors, Cytoplasmic and Nuclear; Valacyclovir

2020