cephalexin has been researched along with cefuroxime in 59 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 22 (37.29) | 18.7374 |
1990's | 7 (11.86) | 18.2507 |
2000's | 14 (23.73) | 29.6817 |
2010's | 14 (23.73) | 24.3611 |
2020's | 2 (3.39) | 2.80 |
Authors | Studies |
---|---|
Braveny, I; Dickert, H; Machka, K | 1 |
Chambers, ST | 1 |
Binder, R; Cole, GW; Collins, JJ; Gooch, WM; Kaminester, L; Morman, MR; Swinehart, JM; Wisniewski, M; Yilmaz, HM | 1 |
Murray, BE; Pickering, LK; Reves, RR; Singh, KV | 1 |
Derriennic, M; Dubreuil, L; Sedallian, A | 1 |
Cocchetto, DM; Gwaltney, JM; Scheld, WM; Sydnor, A | 1 |
Iravani, A; Richard, GA | 1 |
Brewster, G; Silley, P | 1 |
Beskid, G; Durkin, JW; Fallat, V; Lipschitz, ER; McGarry, DH; Siebelist, J | 1 |
Barry, AL; Jones, RN | 1 |
Chin, NX; Neu, HC | 1 |
Anthony, WC; Craig, W; File, TM; Lifland, P; Schleupner, CJ; Tan, J; Vogelman, B | 1 |
Broggio, R; Caro, B; Scheda, P; Xerri, L | 1 |
Fitzgerald, MX; Flavell-Matts, SG; Howell, F; McKenzie, A; McNicholas, W; O'Donovan, C; O'Neill, S; Rudd, R; Whittaker, J | 1 |
Knapp, CC; Washington, JA | 1 |
Barson, WJ; Brady, MT; Cannon, HJ; Grossman, LK | 1 |
Ayers, LW; Barry, AL; Fuchs, PC; Gavan, TL; Gerlach, EH; Jones, RN; Thornsberry, C | 1 |
Hedström, SA; Lidgren, L; Onnerfält, R; Sernbo, I; Törholm, C | 1 |
Concia, E; Marino, P; Marone, P; Verani, D | 1 |
Rahman, M | 1 |
Febvre, N; Juge, F; Lecaillon, JB; Rouan, MC; Souppart, C | 1 |
Barba, D; Esposito, S; Galante, D; Scioli, C | 1 |
Weinstein, AJ | 1 |
Bucholz, RW; Kusmiesz, H; Nelson, JD; Shelton, S | 1 |
Bayston, R; Swinden, J | 1 |
Arpini, A; Di Sipio, L; Minelli, G; Piccolomini, R | 1 |
Palcevski, G; Vitezić, D; Vlahović Palcevski, V | 1 |
Gizatullina, ED; Guryleva, ME; Ozol, SM; Vizel', AA | 1 |
Rose, GE; Vardy, SJ | 1 |
Ogle, JW | 1 |
Halamish, A; Hurvitz, H; Klar, A; Levichek, Z; Shazberg, G | 1 |
Bedenic, B; Bubonja, M; Budimir, A; Topic, M | 1 |
Heikkinen, T; Peltola, V; Ruuskanen, O; Svedström, E; Waris, M | 1 |
Giordano, S; Rintala, R; Taskinen, S | 1 |
Corey, GR; Fowler, VG; Murray, BE; Nannini, EC; Rude, TH; Singh, KV; Stryjewski, ME | 1 |
Ejlertsen, T; Schønheyder, HC; Søgaard, KK | 1 |
Ding, L; Ding, Y; Jia, Y; Jin, X; Liu, W; Lu, C; Song, Y; Wen, A; Yang, J; Yang, L; Zhu, Y | 1 |
Cushing, SL; Gordon, KA; James, AL; Osborn, HA; Papsin, BC | 1 |
Bathini, L; Battistella, M; Garg, AX; Jain, AK; Jandoc, R; Kuwornu, P; Liu, A; McArthur, E; Muanda, FT; Sood, MM; Weir, MA | 1 |
Crawford, SB; Davis, WH; Geno, KA; Magee, MR; Monks, SM | 1 |
Abdo, R; Admasu, D; Bawore, S; Mussema, A; Seid, A | 1 |
Alvarez-Pedraglio, A; Colmenarejo, G; Lavandera, JL | 1 |
Brandsch, M; Luckner, P | 1 |
Biegel, A; Brandsch, M; Gebauer, S; Hartrodt, B; Neubert, K; Thondorf, I | 1 |
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
Lombardo, F; Obach, RS; Waters, NJ | 1 |
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M | 1 |
Duval, V; Glupczynski, Y; Joris, B; Lemaire, S; Tulkens, PM; Van Bambeke, F | 1 |
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
De Luca, F; Delmarcelle, M; Docquier, JD; Dubus, A; Frère, JM; Nacoulma, OG; Rossolini, GM; Simporé, J; Zeba, B | 1 |
Campillo, NE; Guerra, A; Páez, JA | 1 |
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
De Luca, F; Docquier, JD; Fosse, T; Giraud-Morin, C; Rossolini, GM | 1 |
Collins, B; Cotter, PD; Curtis, N; Hill, C; Ross, RP | 1 |
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K | 1 |
Aldini, G; De Luca, L; Marconi, C; Pedretti, A; Regazzoni, L; Vistoli, G | 1 |
de Waart, DR; Duijst, S; Kunne, C; Oude Elferink, RP; Paulusma, CC; van de Wetering, K | 1 |
Bommareddy, A; Gionfriddo, MR; Heindel, GA; Mukhija, P; Vanwert, AL; Witkowski, S; Wolman, AT | 1 |
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
3 review(s) available for cephalexin and cefuroxime
Article | Year |
---|---|
Which cephalosporin?
Topics: Bacterial Infections; Cefazolin; Cefoxitin; Cefuroxime; Cephalexin; Cephalosporins; Drug Costs; Gram-Negative Bacterial Infections; Gram-Positive Bacterial Infections; Humans | 1992 |
The cephalosporins: activity and clinical use.
Topics: Cefaclor; Cefamandole; Cefatrizine; Cefazolin; Cefoxitin; Cefuroxime; Cephacetrile; Cephalexin; Cephaloglycin; Cephaloridine; Cephalosporins; Cephalothin; Cephapirin; Drug Hypersensitivity; Humans; Kidney Diseases | 1980 |
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
7 trial(s) available for cephalexin and cefuroxime
Article | Year |
---|---|
Clinical comparison of cefuroxime axetil, cephalexin and cefadroxil in the treatment of patients with primary infections of the skin or skin structures.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Cefadroxil; Cefuroxime; Cephalexin; Cephalosporins; Child; Child, Preschool; Double-Blind Method; Female; Humans; Male; Middle Aged; Prodrugs; Skin Diseases, Infectious | 1991 |
Single-dose cefuroxime axetil versus multiple-dose cefaclor in the treatment of acute urinary tract infections.
Topics: Acute Disease; Adult; Blood Chemical Analysis; Cefaclor; Cefuroxime; Cephalexin; Cephalosporins; Female; Humans; Urinary Tract Infections | 1989 |
Blinded comparison of cefuroxime to cefaclor for lower respiratory tract infections.
Topics: Acute Disease; Administration, Oral; Adult; Aged; Bacterial Infections; Bronchitis; Cefaclor; Cefuroxime; Cephalexin; Cephalosporins; Clinical Trials as Topic; Drug Therapy; Female; Humans; Male; Middle Aged; Pneumonia; Prodrugs; Random Allocation; Respiratory Tract Infections | 1988 |
Augmentin (intravenous then oral) compared with cefuroxime followed by cephalexin for chest infections in hospitalised patients.
Topics: Amoxicillin; Amoxicillin-Potassium Clavulanate Combination; Cefuroxime; Cephalexin; Cephalosporins; Clavulanic Acids; Clinical Trials as Topic; Humans; Random Allocation; Respiratory Tract Infections | 1987 |
Cefuroxime prophylaxis in trochanteric hip fracture operations.
Topics: Aged; Cefuroxime; Cephalexin; Cephalosporins; Double-Blind Method; Female; Fracture Fixation, Internal; Hip Fractures; Humans; Injections, Intravenous; Male; Middle Aged; Premedication; Random Allocation; Surgical Wound Infection | 1987 |
Prevention of cellulitis after open lacrimal surgery: a prospective study of three methods.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Cefuroxime; Cellulitis; Cephalexin; Cephalosporins; Dacryocystorhinostomy; Erythromycin; Female; Humans; Intraoperative Care; Male; Middle Aged; Postoperative Care; Prospective Studies; Therapeutic Irrigation | 2000 |
Effects of amlodipine on the oral bioavailability of cephalexin and cefuroxime axetil in healthy volunteers.
Topics: Adult; Amlodipine; Anti-Bacterial Agents; Biological Availability; Calcium Channel Blockers; Cefuroxime; Cephalexin; Cross-Over Studies; Humans; Male | 2013 |
49 other study(ies) available for cephalexin and cefuroxime
Article | Year |
---|---|
[Antibacterial activity of cefotaxim in comparison with seven cephalosporins].
Topics: Bacteria; Cefaclor; Cefamandole; Cefazolin; Cefoxitin; Cefuroxime; Cephalexin; Cephalosporins; Cephalothin; Enterobacteriaceae; Escherichia coli; Humans; In Vitro Techniques; Pseudomonas | 1979 |
Comparative in vitro activities of amoxicillin-clavulanic acid, cefuroxime, cephalexin, and cephalothin against trimethoprim-resistant Escherichia coli isolated from stools of children attending day-care centers.
Topics: Amoxicillin; Amoxicillin-Potassium Clavulanate Combination; Anti-Bacterial Agents; Cefuroxime; Cephalexin; Cephalothin; Child Day Care Centers; Child, Preschool; Clavulanic Acids; Drug Therapy, Combination; Escherichia coli; Feces; Humans; Infant; Microbial Sensitivity Tests; Plasmids; Trimethoprim Resistance | 1990 |
[Comparative antibacterial activity of cefpodoxime, cefuroxime and cefaclor against strict anaerobic bacteria].
Topics: Anti-Bacterial Agents; Bacteria, Anaerobic; Cefaclor; Cefpodoxime; Ceftizoxime; Cefuroxime; Cephalexin; Cephalosporins; Dose-Response Relationship, Drug; In Vitro Techniques | 1990 |
Comparative evaluation of cefuroxime axetil and cefaclor for treatment of acute bacterial maxillary sinusitis.
Topics: Acute Disease; Adult; Aged; Bacterial Infections; beta-Lactamases; Cefaclor; Cefuroxime; Cephalexin; Cephalosporins; Drug Evaluation; Female; Haemophilus influenzae; Humans; Male; Maxillary Sinusitis; Middle Aged; Moraxella catarrhalis; Prodrugs; Streptococcus pneumoniae | 1989 |
Kill kinetics of the cephalosporin antibiotics cephalexin and cefuroxime against bacteria of veterinary importance.
Topics: Cefuroxime; Cephalexin; Cephalosporins; Erysipelothrix; Escherichia coli; In Vitro Techniques; Microbial Sensitivity Tests; Pasteurella; Staphylococcus aureus; Streptococcus | 1988 |
In vitro activity of Ro 19-5247 (T-2525) and interpretive criteria for disk diffusion susceptibility testing.
Topics: Acinetobacter; Amoxicillin; Bacteria; Cefaclor; Cefmenoxime; Cefuroxime; Cephalexin; Cephalosporins; Clavulanic Acid; Clavulanic Acids; Enterobacteriaceae; Microbial Sensitivity Tests; Pseudomonas aeruginosa; Staphylococcus; Streptococcus | 1987 |
In vitro evaluation of ceftibuten (7432-S, SCH 39720), a novel orally administered cephalosporin.
Topics: Administration, Oral; Cefaclor; Cefixime; Cefotaxime; Ceftibuten; Cefuroxime; Cephalexin; Cephalosporins; Enterobacteriaceae; Haemophilus influenzae; Microbial Sensitivity Tests; Moraxella catarrhalis; Neisseria meningitidis; Streptococcus | 1988 |
In vitro activity of an oral iminomethoxy aminothiazolyl cephalosporin, R-3746.
Topics: Amoxicillin; Amoxicillin-Potassium Clavulanate Combination; Anti-Bacterial Agents; beta-Lactamases; Cefaclor; Cefixime; Cefotaxime; Cefpodoxime; Ceftizoxime; Cefuroxime; Cephalexin; Cephalosporins; Clavulanic Acids; Culture Media; Drug Combinations; Drug Stability; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; Microbial Sensitivity Tests; Sulfamethoxazole; Trimethoprim; Trimethoprim, Sulfamethoxazole Drug Combination | 1988 |
Importance of inoculum growth phase when using an in vitro pharmacokinetic model to evaluate beta-lactam antibiotics.
Topics: Anti-Bacterial Agents; Cefuroxime; Cephalexin; Cephaloridine; Escherichia coli; Microbial Sensitivity Tests; Staphylococcus aureus | 1988 |
In vitro activities of LY163892, cefaclor, and cefuroxime.
Topics: Anti-Bacterial Agents; Bacteria; Cefaclor; Cefuroxime; Cephalexin; Cephalosporins; Drug Stability; Temperature | 1988 |
Onset of Hemophilus influenzae type-b meningitis during cefaclor therapy for preseptal cellulitis.
Topics: Cefaclor; Ceftriaxone; Cefuroxime; Cellulitis; Cephalexin; Drug Resistance, Microbial; Haemophilus Infections; Haemophilus influenzae; Humans; Infant; Male; Meningitis, Haemophilus; Sepsis | 1987 |
In vitro evaluation of cefixime (FK027, FR17027, CL284635): spectrum against recent clinical isolates, comparative antimicrobial activity, beta-lactamase stability, and preliminary susceptibility testing criteria.
Topics: Amoxicillin; beta-Lactamases; Cefaclor; Cefixime; Cefotaxime; Cefuroxime; Cephalexin; Clavulanic Acid; Clavulanic Acids; Enterobacteriaceae; Escherichia coli; In Vitro Techniques; Pseudomonas; Staphylococcus | 1986 |
[Microbiological evaluation of the antibacterial activity of cefotaxime in comparison with other cephalosporins].
Topics: Bacteria; Cefazolin; Cefoperazone; Cefotaxime; Cefoxitin; Cefuroxime; Cephacetrile; Cephalexin; Cephaloridine; Cephalosporins; Cephalothin; Cephradine; Enterobacter; Escherichia coli; Humans; Klebsiella pneumoniae; Salmonella; Staphylococcus aureus | 1982 |
Sensitivities of clinically significant organisms to four cephalosporins, ampicillin and mecillinam.
Topics: Amdinocillin; Ampicillin; Bacterial Infections; Cefamandole; Cefoxitin; Cefuroxime; Cephalexin; Cephalosporins; Humans; Microbial Sensitivity Tests; Penicillanic Acid | 1980 |
Determination of cefsulodin, cefotiam, cephalexin, cefotaxime, desacetyl-cefotaxime, cefuroxime and cefroxadin in plasma and urine by high-performance liquid chromatography.
Topics: Cefotaxime; Cefotiam; Cefsulodin; Cefuroxime; Cephalexin; Cephalosporins; Cephradine; Chromatography, High Pressure Liquid; Humans; Microchemistry; Structure-Activity Relationship | 1982 |
[Sensitivity of 5 beta-lactam antibiotics to beta-lactamase isolated from E. coli and its respective transconjugates].
Topics: Ampicillin; Anti-Bacterial Agents; beta-Lactamases; Cefotaxime; Cefuroxime; Cephalexin; Cephaloridine; Conjugation, Genetic; Escherichia coli; Humans | 1983 |
Benefits and risks of sequential parenteral--oral cephalosporin therapy for suppurative bone and joint infections.
Topics: Acute Disease; Administration, Oral; Arthritis, Infectious; Bacterial Infections; Cefaclor; Cefamandole; Cefuroxime; Cephalexin; Cephalosporins; Child; Child, Preschool; Drug Therapy, Combination; Female; Humans; Infant; Infusions, Parenteral; Male; Osteoarthritis; Osteomyelitis; Suppuration | 1982 |
Effects of test conditions on the susceptibility of staphylococci in vitro to cephradine, cephaloridine, cephalexin, and cefuroxime.
Topics: Cefuroxime; Cephalexin; Cephaloridine; Cephalosporins; Cephradine; Microbial Sensitivity Tests; Osmolar Concentration; Staphylococcus; Temperature | 1981 |
[In vitro and in vivo antimicrobial activity of cefuroxime cefamandole and cephalexin on freshly isolated strains of Gram-positive and Gram-negative bacteria].
Topics: Animals; Bacteria; Cefamandole; Cefuroxime; Cephalexin; Cephalosporins; Mice; Microbial Sensitivity Tests | 1981 |
Antibiotics utilization during the war period: influence of drug donations.
Topics: Amoxicillin-Potassium Clavulanate Combination; Ampicillin; Anesthesia Department, Hospital; Anti-Bacterial Agents; Anti-Infective Agents; Cefuroxime; Cephalexin; Cephalosporins; Critical Care; Croatia; Drug Therapy, Combination; Drug Utilization; Gentamicins; Hospital Bed Capacity, 500 and over; Hospital Records; Hospitals, University; Humans; International Cooperation; Metronidazole; Penicillins; Pharmacy Service, Hospital; Quality of Health Care; Relief Work; Surgery Department, Hospital; Trimethoprim, Sulfamethoxazole Drug Combination; Warfare | 1997 |
[Antibiotic sensitivity of pathogenic microflora: data of the bacteriological laboratory at the antituberculosis clinic].
Topics: Amoxicillin-Potassium Clavulanate Combination; Ampicillin; Anti-Bacterial Agents; Antibiotics, Antitubercular; Bacteria; Carbenicillin; Cefuroxime; Cephalexin; Cephalosporins; Chloramphenicol; Ciprofloxacin; Doxycycline; Drug Therapy, Combination; Erythromycin; Female; Gentamicins; Humans; Inpatients; Lincomycin; Male; Microbial Sensitivity Tests; Neomycin; Outpatients; Oxacillin; Penicillins; Rifampin; Spiramycin; Streptomycin; Tetracycline | 1998 |
Antimicrobial therapy for ambulatory pediatrics.
Topics: Ambulatory Care; Anti-Bacterial Agents; Anti-Infective Agents; Cefixime; Cefuroxime; Cephalexin; Cephalosporins; Child; Fluoroquinolones; Humans; Macrolides; Otitis Media; Penicillins; Pharyngitis; Pneumonia, Bacterial; Sinusitis; Urinary Tract Infections | 1999 |
Salmonella mastitis in a child.
Topics: Amoxicillin; Anti-Bacterial Agents; Cefuroxime; Cephalexin; Female; Humans; Infant; Mastitis; Salmonella Infections | 2002 |
Urinary bactericidal activity of oral antibiotics against common urinary tract pathogens in an ex vivo model.
Topics: Acetamides; Administration, Oral; Adult; Amoxicillin; Amoxicillin-Potassium Clavulanate Combination; Anti-Bacterial Agents; Anti-Infective Agents, Urinary; beta-Lactamases; Biomarkers; Cefadroxil; Ceftibuten; Cefuroxime; Cephalexin; Cephalosporins; Ciprofloxacin; Disk Diffusion Antimicrobial Tests; Female; Gram-Negative Bacteria; Gram-Negative Bacterial Infections; Gram-Positive Bacteria; Gram-Positive Bacterial Infections; Humans; Linezolid; Middle Aged; Norfloxacin; Oxazolidinones; Time Factors; Trimethoprim, Sulfamethoxazole Drug Combination; Urinary Tract Infections | 2006 |
Pulmonary abscess of viral-bacterial etiology in a neonate.
Topics: Anti-Infective Agents; Cefuroxime; Cephalexin; Escherichia coli Infections; Female; Humans; Infant, Newborn; Lung Abscess; Magnetic Resonance Imaging; Metronidazole; Pneumococcal Infections; Respiratory Syncytial Virus Infections | 2007 |
Xanthogranulomatous pyelonephritis infiltrating the liver.
Topics: Anti-Bacterial Agents; Cefuroxime; Cephalexin; Child; Clindamycin; Combined Modality Therapy; Diverticulum; Escherichia coli Infections; Hepatectomy; Humans; Kidney Calices; Kidney Diseases; Liver; Nephrectomy; Pyelonephritis, Xanthogranulomatous; Trimethoprim | 2008 |
Determination of an inoculum effect with various cephalosporins among clinical isolates of methicillin-susceptible Staphylococcus aureus.
Topics: Anti-Bacterial Agents; Ceftriaxone; Cefuroxime; Cephalexin; Cephalosporins; Cephalothin; Humans; Methicillin; Microbial Sensitivity Tests; Staphylococcal Infections; Staphylococcus aureus | 2010 |
Clostridium difficile 027-associated pseudomembranous colitis after short-term treatment with cefuroxime and cephalexin in an elderly orthopedic patient: a case report.
Topics: Aged; Aged, 80 and over; Cefuroxime; Cephalexin; Clostridioides difficile; Enterocolitis, Pseudomembranous; Humans; Male; Risk Factors | 2012 |
The management of acute mastoiditis in children with cochlear implants: saving the device.
Topics: Acute Disease; Amoxicillin-Potassium Clavulanate Combination; Anti-Bacterial Agents; Cefprozil; Cefuroxime; Cephalexin; Cephalosporins; Child; Child, Preschool; Clindamycin; Cochlear Implantation; Cochlear Implants; Drainage; Female; Hearing Loss, Sensorineural; Humans; Infant; Infusions, Intravenous; Male; Mastoiditis; Otitis Media; Prosthesis-Related Infections; Retrospective Studies; Risk Factors | 2013 |
Clinical Outcomes of Failing to Dose-Reduce Cephalosporin Antibiotics in Older Adults with CKD.
Topics: Aged; Aged, 80 and over; Anti-Bacterial Agents; Cefprozil; Cefuroxime; Cephalexin; Cephalosporins; Databases, Factual; Emergency Service, Hospital; Female; Glomerular Filtration Rate; Hospitalization; Humans; Male; Mortality; Renal Insufficiency, Chronic; Retrospective Studies; Treatment Failure | 2019 |
Assessment of nationally recommended antibiotics for treatment of UTI in U.S.-Mexico border emergency departments.
Topics: Adult; Amoxicillin-Potassium Clavulanate Combination; Anti-Bacterial Agents; Cefdinir; Cefuroxime; Cephalexin; Ciprofloxacin; Emergency Service, Hospital; Fluoroquinolones; Humans; Levofloxacin; Mexico; Nitrofurantoin; Retrospective Studies; Tetracyclines; Trimethoprim, Sulfamethoxazole Drug Combination; United States; Urinary Tract Infections | 2022 |
BACTERIAL PROFILE, ANTIMICROBIAL RESISTANCE, AND FACTORS ASSOCIATED WITH URINARY TRACT INFECTION AMONG PREGNANT WOMEN AT HOSANNA TOWN HEALTH FACILITIES, CENTRAL ETHIOPIA.
Topics: Ampicillin; Anti-Bacterial Agents; Bacteria; Bacteriuria; Cefuroxime; Cephalexin; Cross-Sectional Studies; Doxycycline; Drug Resistance, Bacterial; Escherichia coli; Ethiopia; Female; Gentamicins; Humans; Microbial Sensitivity Tests; Nitrofurantoin; Pregnancy; Pregnant Women; Staphylococcal Infections; Staphylococcus aureus; Trimethoprim, Sulfamethoxazole Drug Combination; Urinary Tract Infections | 2023 |
Cheminformatic models to predict binding affinities to human serum albumin.
Topics: Adrenergic beta-Antagonists; Antidepressive Agents, Tricyclic; Chromatography, Affinity; Cyclooxygenase Inhibitors; Databases, Factual; Humans; Hydrophobic and Hydrophilic Interactions; Penicillins; Pharmaceutical Preparations; Protein Binding; Quantitative Structure-Activity Relationship; Reproducibility of Results; Serum Albumin; Steroids | 2001 |
Interaction of 31 beta-lactam antibiotics with the H+/peptide symporter PEPT2: analysis of affinity constants and comparison with PEPT1.
Topics: Animals; Anti-Bacterial Agents; beta-Lactams; Binding Sites; Caco-2 Cells; Dose-Response Relationship, Drug; Humans; Peptide Transporter 1; Protein Binding; Rats; Symporters | 2005 |
Three-dimensional quantitative structure-activity relationship analyses of beta-lactam antibiotics and tripeptides as substrates of the mammalian H+/peptide cotransporter PEPT1.
Topics: Animals; beta-Lactams; Cell Line, Tumor; Dipeptides; Drug Design; Humans; Mammals; Models, Molecular; Oligopeptides; Peptide Transporter 1; Quantitative Structure-Activity Relationship; Substrate Specificity; Symporters | 2005 |
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship | 2008 |
Activities of ceftobiprole and other cephalosporins against extracellular and intracellular (THP-1 macrophages and keratinocytes) forms of methicillin-susceptible and methicillin-resistant Staphylococcus aureus.
Topics: Anti-Bacterial Agents; Cell Line; Cephalosporins; Dose-Response Relationship, Drug; Humans; Hydrogen-Ion Concentration; Keratinocytes; Macrophages; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Phagocytosis; Ribonucleoproteins; Saccharomyces cerevisiae Proteins; Staphylococcus aureus | 2009 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
IND-6, a highly divergent IND-type metallo-beta-lactamase from Chryseobacterium indologenes strain 597 isolated in Burkina Faso.
Topics: Adult; Amino Acid Sequence; Anti-Bacterial Agents; beta-Lactamases; Cefepime; Ceftazidime; Cephalexin; Cephalosporins; Cephalothin; Chryseobacterium; Female; Humans; Microbial Sensitivity Tests; Molecular Sequence Data; Phylogeny; Protein Structure, Secondary; Sequence Homology, Amino Acid | 2009 |
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical | 2010 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
Genetic and biochemical characterization of TRU-1, the endogenous class C beta-lactamase from Aeromonas enteropelogenes.
Topics: Aeromonas; Amino Acid Sequence; Base Sequence; beta-Lactamases; Cloning, Molecular; DNA Primers; DNA, Bacterial; Drug Resistance, Bacterial; Escherichia coli; Genes, Bacterial; Humans; Kinetics; Molecular Sequence Data; Phylogeny; Sequence Homology, Amino Acid; Sequence Homology, Nucleic Acid; Transformation, Genetic | 2010 |
The ABC transporter AnrAB contributes to the innate resistance of Listeria monocytogenes to nisin, bacitracin, and various beta-lactam antibiotics.
Topics: Anti-Bacterial Agents; ATP-Binding Cassette Transporters; Bacitracin; Bacterial Proteins; beta-Lactam Resistance; Listeria monocytogenes; Nisin | 2010 |
QSAR-based permeability model for drug-like compounds.
Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2011 |
Fragmental modeling of hPepT2 and analysis of its binding features by docking studies and pharmacophore mapping.
Topics: Binding Sites; Computer Simulation; Drug Design; Humans; Ligands; Models, Molecular; Peptides; Protein Binding; Structural Homology, Protein; Symporters | 2011 |
Oral availability of cefadroxil depends on ABCC3 and ABCC4.
Topics: Administration, Oral; Animals; Anti-Bacterial Agents; Biological Availability; Biological Transport; Cefadroxil; Cell Membrane; Enterocytes; Estradiol; Intestinal Absorption; Intestinal Mucosa; Jejunum; Mice; Mice, Knockout; Multidrug Resistance-Associated Proteins | 2012 |
Organic anion transporter 3 interacts selectively with lipophilic β-lactam antibiotics.
Topics: Animals; Anti-Bacterial Agents; beta-Lactams; Biological Transport; Cell Line, Transformed; Humans; Mice; Organic Anion Transport Protein 1; Organic Anion Transporters, Sodium-Independent; Solubility; Structure-Activity Relationship | 2013 |