Page last updated: 2024-08-23

cephalexin and acyclovir

cephalexin has been researched along with acyclovir in 17 studies

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (11.76)18.2507
2000's8 (47.06)29.6817
2010's7 (41.18)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Lombardo, F; Obach, RS; Waters, NJ1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Campillo, NE; Guerra, A; Páez, JA1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
Benet, LZ; Brouwer, KL; Chu, X; Dahlin, A; Evers, R; Fischer, V; Giacomini, KM; Hillgren, KM; Hoffmaster, KA; Huang, SM; Ishikawa, T; Keppler, D; Kim, RB; Lee, CA; Niemi, M; Polli, JW; Sugiyama, Y; Swaan, PW; Tweedie, DJ; Ware, JA; Wright, SH; Yee, SW; Zamek-Gliszczynski, MJ; Zhang, L1
Avdeef, A; Tam, KY1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Balasubramanian, S; Giannadaki, E; Greenstein, AJ; Manousos, ON; Mouzas, IA; Sachar, DB1
de Vrueh, RL; Lee, CP; Smith, PL1
Amidon, GL; Chu, X; Fleisher, D; Komorowski, TE; Landowski, CP; Sun, D; Wallsten, R1
Anderle, P; Chin-Hong, P; Guglielmo, BJ; Lin, ET; Phan, DD; Sadee, W1
Bado, A; Beaufils, B; Buyse, M; Farinotti, R; Hindlet, P; Radeva, G; Walker, F1
Bayart, C; Brandling-Bennett, H; Yang, S1

Reviews

2 review(s) available for cephalexin and acyclovir

ArticleYear
Membrane transporters in drug development.
    Nature reviews. Drug discovery, 2010, Volume: 9, Issue:3

    Topics: Animals; Computer Simulation; Decision Trees; Drug Approval; Drug Discovery; Drug Evaluation, Preclinical; Drug Interactions; Humans; Membrane Transport Proteins; Mice; Mice, Knockout; Prescription Drugs

2010
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Trials

1 trial(s) available for cephalexin and acyclovir

ArticleYear
Intra- and interindividual variabilities of valacyclovir oral bioavailability and effect of coadministration of an hPEPT1 inhibitor.
    Antimicrobial agents and chemotherapy, 2003, Volume: 47, Issue:7

    Topics: Acyclovir; Administration, Oral; Anti-Bacterial Agents; Antiviral Agents; Carrier Proteins; Cephalexin; Drug Interactions; Female; Humans; Male; Peptide Transporter 1; Symporters; Valacyclovir; Valine

2003

Other Studies

14 other study(ies) available for cephalexin and acyclovir

ArticleYear
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:3

    Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical

2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
How well can the Caco-2/Madin-Darby canine kidney models predict effective human jejunal permeability?
    Journal of medicinal chemistry, 2010, May-13, Volume: 53, Issue:9

    Topics: Animals; Disease Models, Animal; Dogs; Humans; Jejunal Diseases; Kidney Diseases; Models, Biological; Permeability; Porosity; Regression Analysis

2010
QSAR-based permeability model for drug-like compounds.
    Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8

    Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2011
Management of varicella infection during the course of inflammatory bowel disease.
    The American journal of gastroenterology, 1997, Volume: 92, Issue:9

    Topics: Acyclovir; Adult; Anti-Inflammatory Agents; Antiviral Agents; Azathioprine; Cause of Death; Cephalexin; Cephalosporins; Chickenpox; Child; Colectomy; Colitis, Ulcerative; Crohn Disease; Female; Glucocorticoids; Humans; Immunocompromised Host; Immunosuppressive Agents; Inflammatory Bowel Diseases; Injections, Intravenous; Male; Megacolon, Toxic; Methylprednisolone; Prednisone; Rectum; Remission Induction; Treatment Outcome

1997
Transport of L-valine-acyclovir via the oligopeptide transporter in the human intestinal cell line, Caco-2.
    The Journal of pharmacology and experimental therapeutics, 1998, Volume: 286, Issue:3

    Topics: Acyclovir; Antiviral Agents; Biological Transport; Caco-2 Cells; Carrier Proteins; Cephalexin; Dose-Response Relationship, Drug; Drug Stability; Humans; Hydrogen-Ion Concentration; Intestinal Mucosa; Valine

1998
Drug inhibition of Gly-Sar uptake and hPepT1 localization using hPepT1-GFP fusion protein.
    AAPS pharmSci, 2001, Volume: 3, Issue:1

    Topics: Acyclovir; Blotting, Western; Caco-2 Cells; Carrier Proteins; Cell Membrane; Cephalexin; Depression, Chemical; Dipeptides; Green Fluorescent Proteins; HeLa Cells; Humans; Luminescent Proteins; Microscopy, Confocal; Peptide Transporter 1; Recombinant Fusion Proteins; Subcellular Fractions; Symporters; Transfection; Valacyclovir; Valine

2001
Regulation of the oligopeptide transporter, PEPT-1, in DSS-induced rat colitis.
    Digestive diseases and sciences, 2007, Volume: 52, Issue:7

    Topics: Acyclovir; Animals; Anti-Bacterial Agents; Antiviral Agents; Biological Availability; Cephalexin; Colitis; Immunohistochemistry; Intestinal Mucosa; Male; Peptide Transporter 1; Rats; Rats, Wistar; RNA, Messenger; Symporters; Valacyclovir; Valine

2007
An atypical presentation of herpes simplex virus infection in Harlequin ichthyosis.
    Pediatric dermatology, 2018, Volume: 35, Issue:6

    Topics: Acyclovir; Anti-Bacterial Agents; Antiviral Agents; Cephalexin; Female; Herpes Simplex; Herpesvirus 1, Human; Humans; Ichthyosis, Lamellar; Infant; Valacyclovir; Valine

2018