centbutindole has been researched along with pyrazines in 9 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (33.33) | 18.7374 |
| 1990's | 2 (22.22) | 18.2507 |
| 2000's | 4 (44.44) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Asthana, OP; Grover, PK; Gupta, RC; Nityanand, S; Paliwal, JK | 1 |
| Bhargava, HN; Gulati, A | 1 |
| Apte, JS; Desai, AB; Doongaji, DR; Satoskar, RS; Shah, BR; Sheth, AS | 1 |
| Dhawan, BN; Gulati, A; Srimal, RC | 1 |
| Apte, JS; Desai, NK; Doongaji, DR; Parikh, RM; Paul, T; Satoskar, RS; Sheth, AS; Upadhaya, AK; Vahora, SA | 1 |
| Gupta, RC; Issar, M; Mishra, B; Singh, SK | 2 |
| Gupta, RC; Issar, M; Madhusudanan, KP; Mishra, B; Singh, SK | 1 |
| Anand, N; Jain, PC; Prathipati, P; Ram, S; Saxena, AK; Saxena, M; Singh, HK; Singh, N | 1 |
1 trial(s) available for centbutindole and pyrazines
| Article | Year |
|---|---|
Centbutindole vs trifluoperazine: a double-blind controlled clinical study in acute schizophrenia.
Topics: Adult; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Male; Pyrazines; Random Allocation; Schizophrenia; Trifluoperazine | 1989 |
8 other study(ies) available for centbutindole and pyrazines
| Article | Year |
|---|---|
Simultaneous determination of centbutindole and its hydroxy metabolite in serum by high-performance liquid chromatography.
Topics: Antipsychotic Agents; Chromatography, High Pressure Liquid; Humans; Hydroxylation; Pyrazines; Reproducibility of Results; Spectrometry, Fluorescence | 1991 |
Effect of melanotropin release inhibiting factor on changes by haloperidol and centbutindole in cerebral cortical 5-hydroxytryptamine receptors.
Topics: Animals; Cerebral Cortex; Haloperidol; Injections, Intraperitoneal; Male; MSH Release-Inhibiting Hormone; Pyrazines; Rats; Rats, Inbred Strains; Receptors, Serotonin; Up-Regulation | 1990 |
Differential alteration in striatal dopaminergic and cortical serotonergic receptors induced by repeated administration of haloperidol or centbutindole in rats.
Topics: 5-Hydroxytryptophan; Animals; Antipsychotic Agents; Apomorphine; Cerebral Cortex; Corpus Striatum; Haloperidol; Male; Pyrazines; Rats; Receptors, Dopamine; Receptors, Serotonin; Spiperone; Stereotyped Behavior | 1988 |
Clinical evaluation of centbutindole as an anti-psychotic agent.
Topics: Adult; Antipsychotic Agents; Drug Evaluation; Humans; Male; Psychiatric Status Rating Scales; Pyrazines; Schizophrenia | 1983 |
A sensitive LC assay for the simultaneous determination of centbutindole and its metabolite in rat serum using fluorescence detection.
Topics: Animals; Antipsychotic Agents; Chromatography, High Pressure Liquid; Fluorescence; Molecular Structure; Pyrazines; Rats; Reference Standards; Reproducibility of Results | 2002 |
Metabolism and excretion of centbutindole (neuroleptic) in rats after oral administration.
Topics: Administration, Oral; Animals; Antipsychotic Agents; Bile; Chromatography, High Pressure Liquid; Dealkylation; Feces; Hydrolysis; In Vitro Techniques; Intestinal Mucosa; Liver; Male; Pyrazines; Rats; Rats, Sprague-Dawley; Time Factors | 2002 |
QSAR studies in substituted 1,2,3,4,6,7,12,12a-octa-hydropyrazino[2',1':6,1]pyrido[3,4-b]indoles--a potent class of neuroleptics.
Topics: Animals; Antipsychotic Agents; Avoidance Learning; Indoles; Pyrazines; Quantitative Structure-Activity Relationship; Rats | 2003 |
Pharmacokinetics, in-situ absorption and protein binding studies of a new neuroleptic agent centbutindole in rats.
Topics: Animals; Antipsychotic Agents; Biological Availability; Intestinal Absorption; Male; Protein Binding; Pyrazines; Rats; Rats, Sprague-Dawley | 2003 |