centa has been researched along with imipenem, anhydrous in 3 studies
| Studies (centa) | Trials (centa) | Recent Studies (post-2010) (centa) | Studies (imipenem, anhydrous) | Trials (imipenem, anhydrous) | Recent Studies (post-2010) (imipenem, anhydrous) |
|---|---|---|---|---|---|
| 8 | 0 | 4 | 4,784 | 391 | 1,397 |
| Protein | Taxonomy | centa (IC50) | imipenem, anhydrous (IC50) |
|---|---|---|---|
| Beta-lactamase | Pseudomonas aeruginosa | 0.15 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bebrone, C; Delbrück, H; Fischer, R; Frère, JM; Galleni, M; Hoffmann, KM; Kupper, MB; Schlömer, P; Willmann, C | 1 |
| Brem, J; Cain, R; Fishwick, CW; Owens, RJ; Rydzik, AM; Salimraj, R; Schofield, CJ; Spencer, J; van Berkel, SS; Verma, A | 1 |
| Bayer, A; Christopeit, T; Guttormsen, Y; Leiros, HK; Lund, BA | 1 |
3 other study(ies) available for centa and imipenem, anhydrous
| Article | Year |
|---|---|
The structure of the dizinc subclass B2 metallo-beta-lactamase CphA reveals that the second inhibitory zinc ion binds in the histidine site.
Topics: Aeromonas hydrophila; Bacterial Proteins; beta-Lactamases; Binding Sites; Calorimetry, Differential Scanning; Circular Dichroism; Crystallography, X-Ray; Histidine; Kinetics; Mutagenesis, Site-Directed; Protein Binding; Protein Structure, Secondary; Zinc | 2009 |
Assay platform for clinically relevant metallo-β-lactamases.
Topics: beta-Lactamase Inhibitors; beta-Lactamases; Enzyme Inhibitors; Magnetic Resonance Spectroscopy; Mass Spectrometry; Metals | 2013 |
Screening and Design of Inhibitor Scaffolds for the Antibiotic Resistance Oxacillinase-48 (OXA-48) through Surface Plasmon Resonance Screening.
Topics: beta-Lactamase Inhibitors; beta-Lactamases; Crystallography, X-Ray; Dose-Response Relationship, Drug; Drug Design; Drug Evaluation, Preclinical; Drug Resistance, Microbial; Humans; Models, Molecular; Molecular Structure; Structure-Activity Relationship; Surface Plasmon Resonance | 2016 |