Page last updated: 2024-08-24

celgosivir and castanospermine

celgosivir has been researched along with castanospermine in 8 studies

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (50.00)18.2507
2000's0 (0.00)29.6817
2010's3 (37.50)24.3611
2020's1 (12.50)2.80

Authors

AuthorsStudies
Behnam, MA; Boldescu, V; Klein, CD; Nitsche, C1
Bowlin, TL; Kang, MS; Liu, PS; Sunkara, PS; Taylor, DL; Tyms, AS1
Ahmed, SP; Bridges, CG; Kang, MS; Nash, RJ; Porter, EA; Taylor, DL; Tyms, AS1
Brennan, TM; Bridges, CG; Kang, MS; Sunkara, PS; Taylor, DL; Tyms, AS1
Torres, G1
Connolly, J; Khoo, YM; Lee, HS; Low, J; Lu, F; Ooi, EE; Rathore, AP; Sung, C; Vasudevan, SG; Watanabe, S1
Aw, P; Chan, KW; Choy, MM; Connolly, JE; de Sessions, PF; Fan, L; Hibberd, ML; Kamaraj, US; Khoo, YM; Lee, B; Lee, HS; Low, JG; Ooi, EE; Rathore, AP; Sessions, OM; Sung, C; Vasudevan, SG; Vijaykrishna, D; Watanabe, S; Wei, Y; Wijaya, L1
Bradfute, SB; Clarke, EC; Nofchissey, RA; Ye, C1

Reviews

1 review(s) available for celgosivir and castanospermine

ArticleYear
The Medicinal Chemistry of Dengue Virus.
    Journal of medicinal chemistry, 2016, 06-23, Volume: 59, Issue:12

    Topics: Antiviral Agents; Chemistry, Pharmaceutical; Dengue; Dengue Virus; Humans; Molecular Conformation; Structure-Activity Relationship

2016

Trials

2 trial(s) available for celgosivir and castanospermine

ArticleYear
BUCAST: another new antiviral.
    GMHC treatment issues : the Gay Men's Health Crisis newsletter of experimental AIDS therapies, 1995, Volume: 9, Issue:11

    Topics: Animals; Antiviral Agents; CD4 Lymphocyte Count; Clinical Trials as Topic; Glycoside Hydrolases; HIV; Humans; Indolizines; Multicenter Studies as Topic; Randomized Controlled Trials as Topic

1995
Extended Evaluation of Virological, Immunological and Pharmacokinetic Endpoints of CELADEN: A Randomized, Placebo-Controlled Trial of Celgosivir in Dengue Fever Patients.
    PLoS neglected tropical diseases, 2016, Volume: 10, Issue:8

    Topics: Adult; Antiviral Agents; Cytokines; Dengue; Dengue Virus; Female; Half-Life; High-Throughput Nucleotide Sequencing; Humans; Indolizines; Male; Phylogeny; Th1 Cells; Viral Load; Viremia; Virus Replication

2016

Other Studies

5 other study(ies) available for celgosivir and castanospermine

ArticleYear
6-0-butanoylcastanospermine (MDL 28,574) inhibits glycoprotein processing and the growth of HIVs.
    AIDS (London, England), 1991, Volume: 5, Issue:6

    Topics: 1-Deoxynojirimycin; alpha-Glucosidases; Animals; Cell Line; Cell Line, Transformed; Dose-Response Relationship, Drug; Gene Products, env; Glucosamine; Glycoside Hydrolase Inhibitors; HIV Envelope Protein gp120; HIV Envelope Protein gp160; HIV-1; Humans; Indolizines; Mice; Moloney murine leukemia virus; Protein Precursors; Viral Plaque Assay; Zalcitabine

1991
Antiviral activity and metabolism of the castanospermine derivative MDL 28,574, in cells infected with herpes simplex virus type 2.
    Biochemical and biophysical research communications, 1995, Mar-08, Volume: 208, Issue:1

    Topics: Animals; Antiviral Agents; Carbon Radioisotopes; Cells, Cultured; Chlorocebus aethiops; Embryo, Mammalian; Fibroblasts; Gas Chromatography-Mass Spectrometry; Glucosidases; Glycoproteins; Herpesvirus 2, Human; Humans; Indolizines; Vero Cells; Viral Plaque Assay

1995
Inhibition of alpha-glucosidase I of the glycoprotein-processing enzymes by 6-O-butanoyl castanospermine (MDL 28,574) and its consequences in human immunodeficiency virus-infected T cells.
    Antimicrobial agents and chemotherapy, 1994, Volume: 38, Issue:8

    Topics: Antiviral Agents; CD4-Positive T-Lymphocytes; Cell Line; Glycoproteins; Glycoside Hydrolase Inhibitors; HIV Envelope Protein gp120; HIV-1; Humans; Indolizines; T-Lymphocytes

1994
Dose- and schedule-dependent protective efficacy of celgosivir in a lethal mouse model for dengue virus infection informs dosing regimen for a proof of concept clinical trial.
    Antiviral research, 2012, Volume: 96, Issue:1

    Topics: Animals; Antiviral Agents; Dengue; Dengue Virus; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Therapy; Indolizines; Mice; Survival Analysis

2012
The iminosugars celgosivir, castanospermine and UV-4 inhibit SARS-CoV-2 replication.
    Glycobiology, 2021, 05-03, Volume: 31, Issue:4

    Topics: 1-Deoxynojirimycin; Animals; Chlorocebus aethiops; COVID-19; COVID-19 Drug Treatment; Glycoside Hydrolase Inhibitors; Humans; Indolizines; SARS-CoV-2; Vero Cells; Virus Replication

2021