celecoxib and thromboxane b2

celecoxib has been researched along with thromboxane b2 in 26 studies

Research

Studies (26)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (11.54)18.2507
2000's16 (61.54)29.6817
2010's7 (26.92)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Borst, P; de Haas, M; Kuil, A; Reid, G; van der Heijden, I; Wielinga, P; Wijnholds, J; Zelcer, N1
Geis, GS; Hubbard, RC; Isakson, PC; Lanza, FL; Lipsky, PE; Schwartz, BD; Simon, LS; Talwalker, S1
Isakson, PC; Koboldt, CM; Masferrer, JL; Muhammad, J; Seibert, K; Shaffer, A; Smith, CJ; Talley, JJ; Zhang, Y; Zweifel, BS1
Catella-Lawson, F; FitzGerald, GA; Kapoor, S; Lawson, JA; Mardini, IA; McAdam, BF1
Geis, GS; Hubbard, RC; Isakson, PC; Karim, A; Leese, PT; Yu, SS1
Cole, CE; Jacoby, RF; Kelloff, G; Lubet, RA; Seibert, K1
Koki, AT; Leahy, KM; Masferrer, JL; Ornberg, RL; Wang, Y; Zweifel, BS1
Bing, RJ; Ingram, M; Miyataka, M; Rich, KA; Yamamoto, T1
Brahim, JS; Dionne, RA; Khan, AA; Rowan, JS1
Adler, R; Eskra, J; Noveck, R; Rushing, M; Vargas, R; Walden, C; Wilner, KD1
Akmal, Y; Ang, JG; Beharry, K; Modanlou, HD; Nishihara, KC; Ozaki, N1
Calixto, JB; Pinheiro, RM1
Akmal, Y; Asrat, T; Beharry, K; Hausman, N; Nishihara, K1
Fukunaga, M; Hayashi, A; Kimoto, A; Kobayashi, S; Miyata, K; Noguchi, M; Sasamata, M; Yoshino, T1
Frölich, JC; Gutzki, FM; Marhauer, V; Stichtenoth, DO; Tsikas, D1
Capone, ML; D'Amelio, E; De Caterina, R; Grana, M; Patrignani, P; Patrono, C; Price, TS; Renda, G; Sacchetta, D; Santarelli, F; Sciulli, MG; Tacconelli, S; Zimarino, M; Zurro, M1
Gertz, BJ; Gottesdiener, KM; Hilliard, DA; Hreniuk, D; Lasseter, KC; Miller, J; Schwartz, JI; Snyder, KM; Thach, C1
Dahlén, SE; Kumlin, M; Låstbom, L; Ryrfeldt, A; Selg, E1
Cavanaugh, PF; Chappell, DL; Dallob, AL; Flynn, ME; Hilliard, DA; Larson, PJ; Laterza, OF; Miller, J; Royalty, J; Schwartz, JI; Snyder, KM; Wagner, JA1
Baker, LD; Breitner, JC; Milne, G; Montine, TJ; Sonnen, JA1
Alamuddin, N; Cen, L; Fitzgerald, GA; Lawson, JA; Propert, KJ; Skarke, C1
Chen, KH; Chiang, LL; Lee, HL; Su, CL; Wang, D; Yuan, DW1
Amin, AR; Dave, M1
Meschede, AK; Schebb, NH; Willenberg, I1
Altavilla, D; Arcoraci, V; Bitto, A; Galfo, F; Irrera, N; Macrì, A; Minutoli, L; Pallio, G; Pizzino, G; Squadrito, F; Squadrito, G1
Brown, MD; Cook, MD; Grimm, H; Kretzschmar, J1

Trials

10 trial(s) available for celecoxib and thromboxane b2

ArticleYear
Preliminary study of the safety and efficacy of SC-58635, a novel cyclooxygenase 2 inhibitor: efficacy and safety in two placebo-controlled trials in osteoarthritis and rheumatoid arthritis, and studies of gastrointestinal and platelet effects.
    Arthritis and rheumatism, 1998, Volume: 41, Issue:9

    Topics: Adult; Aged; Aged, 80 and over; Arthritis, Rheumatoid; Aspirin; Celecoxib; Cyclooxygenase Inhibitors; Endoscopy; Female; Humans; Knee Joint; Male; Middle Aged; Naproxen; Osteoarthritis; Platelet Aggregation; Platelet Aggregation Inhibitors; Pyrazoles; Safety; Severity of Illness Index; Stomach Ulcer; Sulfonamides; Thromboxane B2; Treatment Outcome

1998
Effects of celecoxib, a novel cyclooxygenase-2 inhibitor, on platelet function in healthy adults: a randomized, controlled trial.
    Journal of clinical pharmacology, 2000, Volume: 40, Issue:2

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adolescent; Adult; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Bleeding Time; Blood Platelets; Celecoxib; Collagen; Cyclooxygenase Inhibitors; Double-Blind Method; Female; Humans; Male; Middle Aged; Platelet Aggregation; Pyrazoles; Sulfonamides; Thromboxane B2

2000
In vivo selectivity of a selective cyclooxygenase 2 inhibitor in the oral surgery model.
    Clinical pharmacology and therapeutics, 2002, Volume: 72, Issue:1

    Topics: Adult; Celecoxib; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Double-Blind Method; Enzyme-Linked Immunosorbent Assay; Female; Humans; Ibuprofen; Isoenzymes; Male; Membrane Proteins; Microdialysis; Molar, Third; Oral Surgical Procedures; Pain Measurement; Pain, Postoperative; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Substrate Specificity; Sulfonamides; Thromboxane B2; Tooth Extraction

2002
Celecoxib does not affect the antiplatelet activity of aspirin in healthy volunteers.
    Journal of clinical pharmacology, 2002, Volume: 42, Issue:9

    Topics: Adenosine Diphosphate; Adolescent; Adult; Arachidonic Acid; Aspirin; Celecoxib; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Double-Blind Method; Drug Interactions; Female; Humans; Isoenzymes; Male; Membrane Proteins; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Sulfonamides; Thromboxane B2

2002
Effects of specific COX-2-inhibition on renin release and renal and systemic prostanoid synthesis in healthy volunteers.
    Kidney international, 2005, Volume: 68, Issue:5

    Topics: 6-Ketoprostaglandin F1 alpha; Adult; Aldosterone; Body Weight; Celecoxib; Creatinine; Cross-Over Studies; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Diuretics; Female; Furosemide; Humans; Indomethacin; Kidney; Potassium; Prostaglandins; Pyrazoles; Renin; Sodium; Sulfonamides; Thromboxane B2

2005
Celecoxib, ibuprofen, and the antiplatelet effect of aspirin in patients with osteoarthritis and ischemic heart disease.
    Clinical pharmacology and therapeutics, 2006, Volume: 80, Issue:3

    Topics: Adenosine Diphosphate; Aged; Arachidonic Acid; Aspirin; Celecoxib; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Ibuprofen; Male; Middle Aged; Myocardial Ischemia; Osteoarthritis; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Pyrazoles; Sulfonamides; Thromboxane B2; Treatment Outcome

2006
Effects of etoricoxib and comparator nonsteroidal anti-inflammatory drugs on urinary sodium excretion, blood pressure, and other renal function indicators in elderly subjects consuming a controlled sodium diet.
    Journal of clinical pharmacology, 2007, Volume: 47, Issue:12

    Topics: 6-Ketoprostaglandin F1 alpha; Administration, Oral; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Blood Pressure; Body Weight; Celecoxib; Constipation; Creatinine; Diarrhea; Dose-Response Relationship, Drug; Double-Blind Method; Electrolytes; Etoricoxib; Female; Headache; Humans; Male; Middle Aged; Naproxen; Potassium; Prostaglandins; Pyrazoles; Pyridines; Sodium; Sulfonamides; Sulfones; Thromboxane B2

2007
Comparative inhibitory activity of etoricoxib, celecoxib, and diclofenac on COX-2 versus COX-1 in healthy subjects.
    Journal of clinical pharmacology, 2008, Volume: 48, Issue:6

    Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Cross-Over Studies; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Diclofenac; Dinoprostone; Double-Blind Method; Etoricoxib; Female; Humans; Male; Middle Aged; Pyrazoles; Pyridines; Sulfonamides; Sulfones; Thromboxane B2

2008
Elevated ratio of urinary metabolites of thromboxane and prostacyclin is associated with adverse cardiovascular events in ADAPT.
    PloS one, 2010, Feb-19, Volume: 5, Issue:2

    Topics: 6-Ketoprostaglandin F1 alpha; Aged; Aged, 80 and over; Alzheimer Disease; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cardiovascular Diseases; Celecoxib; Drug Therapy, Combination; F2-Isoprostanes; Female; Humans; Male; Naproxen; Pyrazoles; Sulfonamides; Thromboxane B2; Treatment Outcome

2010
Comparative impact on prostanoid biosynthesis of celecoxib and the novel nonsteroidal anti-inflammatory drug CG100649.
    Clinical pharmacology and therapeutics, 2012, Volume: 91, Issue:6

    Topics: 6-Ketoprostaglandin F1 alpha; Adolescent; Adult; Anti-Inflammatory Agents, Non-Steroidal; Area Under Curve; Asian; Black People; Carbonic Anhydrase Inhibitors; Cardiovascular Diseases; Celecoxib; Cross-Over Studies; Cyclooxygenase 2 Inhibitors; Double-Blind Method; Epoprostenol; Female; Furans; Humans; Male; Middle Aged; Prostaglandin Antagonists; Prostaglandins; Pyrazoles; Risk Assessment; Sulfonamides; Thromboxane B2; White People; Young Adult

2012

Other Studies

16 other study(ies) available for celecoxib and thromboxane b2

ArticleYear
The human multidrug resistance protein MRP4 functions as a prostaglandin efflux transporter and is inhibited by nonsteroidal antiinflammatory drugs.
    Proceedings of the National Academy of Sciences of the United States of America, 2003, Aug-05, Volume: 100, Issue:16

    Topics: Adenosine Triphosphate; Alprostadil; Animals; Anti-Inflammatory Agents, Non-Steroidal; Biological Transport; Cell Line; Cell Membrane; Diffusion; Dinoprost; Dinoprostone; Dose-Response Relationship, Drug; Humans; Insecta; Multidrug Resistance-Associated Proteins; Prostaglandins; Prostaglandins A; Prostaglandins F; Ribosomal Proteins; RNA Interference; RNA, Small Interfering; Thromboxane B2; Time Factors

2003
Pharmacological analysis of cyclooxygenase-1 in inflammation.
    Proceedings of the National Academy of Sciences of the United States of America, 1998, Oct-27, Volume: 95, Issue:22

    Topics: Animals; Arthritis, Experimental; Blood Platelets; Carrageenan; Celecoxib; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Edema; Hyperalgesia; Indomethacin; Inflammation; Isoenzymes; Male; Membrane Proteins; Models, Biological; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Sulfonamides; Thromboxane B2

1998
Systemic biosynthesis of prostacyclin by cyclooxygenase (COX)-2: the human pharmacology of a selective inhibitor of COX-2.
    Proceedings of the National Academy of Sciences of the United States of America, 1999, Jan-05, Volume: 96, Issue:1

    Topics: 6-Ketoprostaglandin F1 alpha; Adult; Celecoxib; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Epoprostenol; Female; Humans; Ibuprofen; Isoenzymes; Male; Membrane Proteins; Middle Aged; Monocytes; Platelet Aggregation; Platelet Aggregation Inhibitors; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Sulfonamides; Thromboxane B2

1999
The cyclooxygenase-2 inhibitor celecoxib is a potent preventive and therapeutic agent in the min mouse model of adenomatous polyposis.
    Cancer research, 2000, Sep-15, Volume: 60, Issue:18

    Topics: Adenomatous Polyposis Coli; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anticarcinogenic Agents; Antineoplastic Agents; Celecoxib; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Disease Models, Animal; Female; Isoenzymes; Male; Membrane Proteins; Mice; Mice, Inbred C57BL; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Substrate Specificity; Sulfonamides; Thromboxane B2

2000
Cyclooxygenase-2 inhibition by celecoxib reduces proliferation and induces apoptosis in angiogenic endothelial cells in vivo.
    Cancer research, 2002, Feb-01, Volume: 62, Issue:3

    Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Apoptosis; Celecoxib; Cell Division; Colonic Neoplasms; Cornea; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Endothelium, Vascular; Fibroblast Growth Factor 2; Humans; Isoenzymes; Membrane Proteins; Mice; Mice, Nude; Neovascularization, Pathologic; Neovascularization, Physiologic; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Rats; Sulfonamides; Thromboxane B2; Xenograft Model Antitumor Assays

2002
Nitric oxide, anti-inflammatory drugs on renal prostaglandins and cyclooxygenase-2.
    Hypertension (Dallas, Tex. : 1979), 2002, Mar-01, Volume: 39, Issue:3

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Celecoxib; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Isoenzymes; Kidney; Male; Nitrates; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrobenzenes; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Prostaglandins F; Pyrazoles; Rabbits; Salicylates; Sulfonamides; Thromboxane B2

2002
Differential regulation of prostacyclin and thromboxane by dexamethasone and celecoxib during oxidative stress in newborn rabbits.
    Prostaglandins & other lipid mediators, 2002, Volume: 70, Issue:1-2

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Animals, Newborn; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Dexamethasone; Dinoprost; Epoprostenol; F2-Isoprostanes; Hyperoxia; Oxidative Stress; Pyrazoles; Rabbits; Sulfonamides; Thromboxane B2

2002
Effect of the selective COX-2 inhibitors, celecoxib and rofecoxib in rat acute models of inflammation.
    Inflammation research : official journal of the European Histamine Research Society ... [et al.], 2002, Volume: 51, Issue:12

    Topics: Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Celecoxib; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dexamethasone; Dinoprostone; Edema; Indomethacin; Inflammation; Interleukin-1; Isoenzymes; Lactones; Male; Nitric Oxide; Peroxidase; Pleurisy; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Rats; Rats, Wistar; Sulfonamides; Sulfones; Thromboxane B2; Tumor Necrosis Factor-alpha

2002
Antenatal administration of celecoxib, a selective cyclooxygenase (COX)-2 inhibitor, appears to improve placental perfusion in the pregnant rabbit.
    Prostaglandins & other lipid mediators, 2003, Volume: 70, Issue:3-4

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Body Weight; Celecoxib; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Female; Isoenzymes; Nitric Oxide; Organ Size; Perfusion; Placenta; Pregnancy; Pregnancy, Animal; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Pyrazoles; Rabbits; Sulfonamides; Thromboxane B2; Time Factors

2003
Pharmacological profile of celecoxib, a specific cyclooxygenase-2 inhibitor.
    Arzneimittel-Forschung, 2005, Volume: 55, Issue:7

    Topics: Animals; Carrageenan; Celecoxib; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Fever; Fibroblasts; Humans; Hyperalgesia; In Vitro Techniques; Interleukin-1; Lipopolysaccharides; Lymphoma; Male; Membrane Proteins; Platelet Aggregation; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Rats; Rats, Sprague-Dawley; Stomach Ulcer; Sulfonamides; Thromboxane B2; Tumor Cells, Cultured

2005
Effects of selective and non-selective COX inhibitors on antigen-induced release of prostanoid mediators and bronchoconstriction in the isolated perfused and ventilated guinea pig lung.
    Prostaglandins, leukotrienes, and essential fatty acids, 2008, Volume: 78, Issue:2

    Topics: Animals; Bronchoconstriction; Celecoxib; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Diclofenac; Flurbiprofen; Guinea Pigs; Humans; Leukotrienes; Lung; Male; Ovalbumin; Piperazines; Prostaglandins; Pyrazoles; Sulfonamides; Thiazoles; Thromboxane A2; Thromboxane B2

2008
Inducible cyclooxygenase expression mediating hypoxia/reoxygenation-induced pulmonary vasoconstriction is attenuated by a cyclooxygenase inhibitor in rats.
    Transplantation proceedings, 2012, Volume: 44, Issue:4

    Topics: Animals; Biomarkers; Blood Pressure; Celecoxib; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Disease Models, Animal; Hydroxyl Radical; Hypoxia; Inflammation Mediators; Nitric Oxide; Oxidative Stress; Perfusion; Pulmonary Artery; Pyrazoles; Rats; Rats, Sprague-Dawley; RNA, Messenger; Sulfonamides; Thromboxane B2; Time Factors; Vasoconstriction

2012
Yin-Yang regulation of prostaglandins and nitric oxide by PGD2 in human arthritis: reversal by celecoxib.
    Immunology letters, 2013, Volume: 152, Issue:1

    Topics: Celecoxib; Cells, Cultured; Chondrocytes; Dinoprost; Dinoprostone; Humans; Inflammation Mediators; Interleukin-1beta; Knee; Leukotriene B4; Nitric Oxide; Osteoarthritis; Prostaglandin D2; Prostaglandins F; Pyrazoles; Sulfonamides; Thromboxane B2

2013
Determining cyclooxygenase-2 activity in three different test systems utilizing online-solid phase extraction-liquid chromatography-mass spectrometry for parallel quantification of prostaglandin E(2), D(2) and thromboxane B(2).
    Journal of chromatography. A, 2015, Apr-24, Volume: 1391

    Topics: Celecoxib; Cell Line; Chromatography, Liquid; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Dexamethasone; Dinoprostone; Humans; Indomethacin; Lipopolysaccharides; Monocytes; Prostaglandin D2; Pyrazoles; Recombinant Proteins; Solid Phase Extraction; Spectrometry, Mass, Electrospray Ionization; Sulfonamides; Tandem Mass Spectrometry; Thromboxane B2

2015
Use of a balanced dual cyclooxygenase-1/2 and 5-lypoxygenase inhibitor in experimental colitis.
    European journal of pharmacology, 2016, Oct-15, Volume: 789

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Apoptosis; Arachidonate 5-Lipoxygenase; Body Weight; Catechin; CD3 Complex; Celecoxib; Colitis; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Dinoprostone; Drug Combinations; Eating; Gene Expression Regulation; Hydroxyurea; Leukotriene B4; Lipid Peroxidation; Lipoxygenase Inhibitors; Male; Neutrophil Infiltration; Rats; Rats, Sprague-Dawley; Thromboxane B2; Tumor Necrosis Factor-alpha

2016
The Effects of Exercise, Aspirin, and Celecoxib in an Atherogenic Environment.
    Medicine and science in sports and exercise, 2018, Volume: 50, Issue:10

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Atherosclerosis; Celecoxib; Cells, Cultured; Epoprostenol; Exercise; Human Umbilical Vein Endothelial Cells; Humans; Inflammation; Nitric Oxide Synthase Type III; Stress, Mechanical; Thromboxane B2; Tumor Necrosis Factor-alpha

2018