celecoxib and sulindac

celecoxib has been researched along with sulindac in 44 studies

Research

Studies (44)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	23 (52.27)	29.6817
2010's	19 (43.18)	24.3611
2020's	2 (4.55)	2.80

Authors

Authors	Studies
Blobaum, AL; Crews, BC; Daniel, CM; Ghebreselasie, K; Kingsley, PJ; Liedtke, AJ; Marnett, LJ	1
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM	1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM	1
Barreiro, EJ; Cardozo, SV; de Miranda, AL; Fraga, CA; Leite, RD; Lima, LM; Romeiro, NC	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Ekins, S; Williams, AJ; Xu, JJ	1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Koki, A; Myers, C; Padley, RJ; Pamukcu, R; Wechter, W	1
Chau, I; Cunningham, D	1
Bauer, WM; Burke, CA; Lashner, B	1
Hashitani, S; Maeda, T; Nishimura, N; Noguchi, K; Sakurai, K; Takaoka, K; Urade, M	1
Blumenthal, M; Chen, TC; Kardosh, A; Schönthal, AH; Wang, WJ	1
Chen, Y; Fu, SL; Qiao, MM; Wu, YL; Zhang, YP	1
Dubois, RN; Koehne, CH	1
Lin, YS; Tsao, PN; Wei, SC; Wong, JM; Wu, CH; Wu-Tsai, JJ	1
Narayanan, BA; Narayanan, NK; Pittman, B; Reddy, BS	1
Raskov, HH	1
Arana, A; Castellsague, J; Perez-Gutthann, S; Sanchez-Matienzo, D	1
Bedford, NS; Bock, JM; Domann, FE; Goswami, PC; Menon, SG; Sinclair, LL; Trask, DK	1
Nikitakis, NG; Sauk, JJ; Scheper, MA	1
Lynch, PM	2
Bosland, MC; Horton, L; Narayanan, BA; Narayanan, NK; Nargi, D; Randolph, C; Reddy, BS	1
Doll, MA; Feng, Y; Hein, DW; Neale, JR	1
Tuma, R	1
Xiao, H; Yang, CS	1
Aderinto, A; Di Cello, F; Hillion, J; Huso, DL; Kowalski, J; Resar, LM; Ronnett, BM	1
Besselsen, DG; Blohm-Mangone, KA; Cui, H; Gerner, EW; Ignatenko, NA; Stringer, DE	1
Gerner, EW; Thompson, PA	1
Sanyal, SN; Vaish, V	3
Manzano, A; Pérez-Segura, P	1
Piplani, H; Rana, C; Sanyal, SN; Vaish, V	1
Grimaldi, M; Hobrath, JV; Johnson, GG; Piazza, GA; White, MC; Zhang, W	1
Piplani, H; Rana, C; Sanyal, SN; Vaiphei, K; Vaish, V	2
Acuna, UM; Einbond, LS; Figueroa, M; Foster, DA; Jalees, F; Kashiwazaki, R; Kennelly, EJ; Le Gendre, O; Mighty, J	1
Barnholtz-Sloan, JS; Chen, Y; Dawson, DM; Fink, SP; Kopelovich, L; Kresak, A; Lawrence, EG; Markowitz, SD; Willis, JE; Yang, P; Zhang, Y	1
Cha, BK; Cho, KH; Hwang, KE; Jeong, ET; Jun, HY; Kim, BR; Kim, HR; Kim, YS; Oh, SH; Yoon, KH	1
Chen, CH; Cheng, TS; Hsiao, PW; Hsu, TW; Huang, HP; Ko, CJ; Lai, PF; Lan, SW; Lee, MS; Lin, HH; Lin, HY; Lu, YC; Shyu, HY; Tsai, CH; Wu, SR	1
Burke, CA; Chick, RC; Cindass, JL; Clifton, GT; Ensley, DC; Hale, DF; Hickerson, AT; Kemp Bohan, PM; Mankaney, G; Peoples, GE; Sohn, V; Vreeland, TJ	1
Augustijns, P; Brouwers, J; Lemmens, G; Snoeys, J; Vanuytsel, T	1

Reviews

8 review(s) available for celecoxib and sulindac

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
Chemoprevention of colorectal cancer: slow, steady progress. Cleveland Clinic journal of medicine, 2003, Volume: 70, Issue:4 Topics: Adenomatous Polyposis Coli; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Aspirin; Celecoxib; Colorectal Neoplasms; Folic Acid; Humans; Pyrazoles; Sulfonamides; Sulindac	2003
COX-2 inhibition and colorectal cancer. Seminars in oncology, 2004, Volume: 31, Issue:2 Suppl 7 Topics: Adenomatous Polyposis Coli; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Celecoxib; Clinical Trials as Topic; Colorectal Neoplasms; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Humans; Isoenzymes; Membrane Proteins; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Sulfonamides; Sulindac	2004
[Non-steroidal anti-inflammatory agents and prevention of colorectal adenomas and carcinomas]. Ugeskrift for laeger, 2006, Jan-23, Volume: 168, Issue:4 Topics: Adenoma; Adenomatous Polyposis Coli; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Aspirin; Carcinoma; Celecoxib; Colorectal Neoplasms; Evidence-Based Medicine; Humans; Meta-Analysis as Topic; Pyrazoles; Sulfonamides; Sulindac	2006
Combination regimen with statins and NSAIDs: a promising strategy for cancer chemoprevention. International journal of cancer, 2008, Sep-01, Volume: 123, Issue:5 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Anticarcinogenic Agents; Aspirin; Atorvastatin; Celecoxib; Colorectal Neoplasms; Drug Administration Schedule; Drug Synergism; Drug Therapy, Combination; Evidence-Based Medicine; Fatty Acids, Monounsaturated; Fluvastatin; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Indoles; Lovastatin; Meta-Analysis as Topic; Neoplasms; Pravastatin; Pyrazoles; Pyridines; Pyrroles; Randomized Controlled Trials as Topic; Simvastatin; Sulfonamides; Sulindac	2008
Colorectal cancer chemoprevention: is this the future of colorectal cancer prevention? TheScientificWorldJournal, 2012, Volume: 2012 Topics: Adenoma; Adenomatous Polyposis Coli; Adult; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Celecoxib; Chemoprevention; Colorectal Neoplasms; Cyclooxygenase 2 Inhibitors; Humans; Pyrazoles; Randomized Controlled Trials as Topic; Sulfonamides; Sulindac	2012
Chemoprevention of familial adenomatous polyposis. Familial cancer, 2016, Volume: 15, Issue:3 Topics: Adenomatous Polyposis Coli; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Aspirin; Celecoxib; Chemotherapy, Adjuvant; Clinical Trials as Topic; Colectomy; Cyclooxygenase 2 Inhibitors; Drug Resistance, Neoplasm; Drug Synergism; Drug Therapy, Combination; Eflornithine; Evidence-Based Medicine; Humans; Prophylactic Surgical Procedures; Remission Induction; Sulindac	2016
Chemoprevention in familial adenomatous polyposis: past, present and future. Familial cancer, 2021, Volume: 20, Issue:1 Topics: Adenomatous Polyposis Coli; Anti-Inflammatory Agents, Non-Steroidal; Antibiotics, Antineoplastic; Ascorbic Acid; Aspirin; Capsules; Celecoxib; Chemoprevention; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Drug Therapy, Combination; Eflornithine; Erlotinib Hydrochloride; Fatty Acids, Nonesterified; Genes, APC; Humans; Sirolimus; Sulindac; TOR Serine-Threonine Kinases; Vitamins	2021

Other Studies

36 other study(ies) available for celecoxib and sulindac

Article	Year
Cyclooxygenase-1-selective inhibitors based on the (E)-2'-des-methyl-sulindac sulfide scaffold. Journal of medicinal chemistry, 2012, Mar-08, Volume: 55, Issue:5 Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Cyclooxygenase 1; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Drug Screening Assays, Antitumor; Female; Humans; Hydrophobic and Hydrophilic Interactions; Mice; Sheep; Stereoisomerism; Structure-Activity Relationship; Sulindac	2012
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2). Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11 Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship	2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1. Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19 Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship	2008
Synthesis, pharmacological evaluation and docking studies of new sulindac analogues. European journal of medicinal chemistry, 2009, Volume: 44, Issue:5 Topics: Anti-Inflammatory Agents, Non-Steroidal; Cell Membrane Permeability; Computer Simulation; Cyclooxygenase 1; Cyclooxygenase 2; Drug Design; Humans; Prodrugs; Protein Binding; Structure-Activity Relationship; Sulindac	2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
A predictive ligand-based Bayesian model for human drug-induced liver injury. Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12 Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands	2010
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
Proapoptotic anti-inflammatory drugs. Urology, 2001, Volume: 57, Issue:4 Suppl 1 Topics: Angiogenesis Inhibitors; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Celecoxib; Colonic Neoplasms; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Flurbiprofen; Humans; Isoenzymes; Male; Membrane Proteins; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Rats; Sulfonamides; Sulindac	2001
Cyclooxygenase inhibition in cancer--a blind alley or a new therapeutic reality? The New England journal of medicine, 2002, Apr-04, Volume: 346, Issue:14 Topics: Adenomatous Polyposis Coli; Adenomatous Polyps; Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Colonic Polyps; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Genes, APC; Germ-Line Mutation; Humans; Isoenzymes; Membrane Proteins; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Sulfonamides; Sulindac	2002
Apoptosis induction and enhancement of cytotoxicity of anticancer drugs by celecoxib, a selective cyclooxygenase-2 inhibitor, in human head and neck carcinoma cell lines. International journal of oncology, 2003, Volume: 23, Issue:3 Topics: Antibiotics, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Apoptosis; Bleomycin; Blotting, Western; Carcinoma; Celecoxib; Cell Line, Tumor; Cell Survival; Cisplatin; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; DNA Fragmentation; Dose-Response Relationship, Drug; Doxorubicin; Drug Synergism; Fluorouracil; Head and Neck Neoplasms; Humans; Inhibitory Concentration 50; Isoenzymes; Membrane Proteins; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Sulfonamides; Sulindac; Time Factors; Vincristine	2003
Differential effects of selective COX-2 inhibitors on cell cycle regulation and proliferation of glioblastoma cell lines. Cancer biology & therapy, 2004, Volume: 3, Issue:1 Topics: Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Cell Cycle; Cell Division; Cell Line, Tumor; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Glioblastoma; Humans; Indomethacin; Isoenzymes; Isoxazoles; Lactones; Membrane Proteins; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Sulfonamides; Sulfones; Sulindac	2004
Anti-cancer effects of COX-2 inhibitors and their correlation with angiogenesis and invasion in gastric cancer. World journal of gastroenterology, 2004, Jul-01, Volume: 10, Issue:13 Topics: Animals; Apoptosis; Celecoxib; Cell Division; Cell Line, Tumor; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Humans; Isoenzymes; Male; Membrane Proteins; Mice; Mice, Nude; Neoplasm Invasiveness; Neovascularization, Pathologic; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Stomach Neoplasms; Sulfonamides; Sulindac; Xenograft Model Antitumor Assays	2004
Comparison of the anti-proliferation and apoptosis-induction activities of sulindac, celecoxib, curcumin, and nifedipine in mismatch repair-deficient cell lines. Journal of the Formosan Medical Association = Taiwan yi zhi, 2004, Volume: 103, Issue:8 Topics: Antineoplastic Agents; Apoptosis; Celecoxib; Cell Cycle; Cell Line, Tumor; Chemoprevention; Colorectal Neoplasms; Curcumin; Endometrial Neoplasms; Female; Humans; Nifedipine; Pyrazoles; Sulfonamides; Sulindac	2004
Regression of mouse prostatic intraepithelial neoplasia by nonsteroidal anti-inflammatory drugs in the transgenic adenocarcinoma mouse prostate model. Clinical cancer research : an official journal of the American Association for Cancer Research, 2004, Nov-15, Volume: 10, Issue:22 Topics: Adenocarcinoma; Animals; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Blotting, Western; Celecoxib; Dietary Supplements; Dinoprostone; Disease Models, Animal; Immunohistochemistry; Male; Mice; Mice, Transgenic; Models, Biological; Phosphorylation; Prostatic Intraepithelial Neoplasia; Prostatic Neoplasms; Pyrazoles; Sulfonamides; Sulindac; Time Factors; Transgenes	2004
Hepatic disorders in patients treated with COX-2 selective inhibitors or nonselective NSAIDs: a case/noncase analysis of spontaneous reports. Clinical therapeutics, 2006, Volume: 28, Issue:8 Topics: Anti-Inflammatory Agents, Non-Steroidal; Benzophenones; Bromobenzenes; Celecoxib; Chemical and Drug Induced Liver Injury; Cyclooxygenase 2 Inhibitors; Humans; Lactones; Odds Ratio; Pyrazoles; Safety; Sulfonamides; Sulfones; Sulindac	2006
Relative non-steroidal anti-inflammatory drug (NSAID) antiproliferative activity is mediated through p21-induced G1 arrest and E2F inhibition. Molecular carcinogenesis, 2007, Volume: 46, Issue:10 Topics: Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Celecoxib; Cell Proliferation; Cyclin-Dependent Kinase Inhibitor p21; E2F Transcription Factors; G1 Phase; Humans; Pyrazoles; Sulfonamides; Sulindac; Tumor Cells, Cultured	2007
Survivin is a downstream target and effector of sulindac-sensitive oncogenic Stat3 signalling in head and neck cancer. International journal of oral and maxillofacial surgery, 2007, Volume: 36, Issue:7 Topics: Annexin A5; Antineoplastic Agents; Apoptosis; Carcinoma, Squamous Cell; Celecoxib; Cell Division; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cyclooxygenase 2 Inhibitors; Cysteine Proteinase Inhibitors; Down-Regulation; Enzyme Inhibitors; Humans; Immunohistochemistry; Indomethacin; Inhibitor of Apoptosis Proteins; Microtubule-Associated Proteins; Neoplasm Proteins; Pyrazoles; Signal Transduction; STAT3 Transcription Factor; Sulfonamides; Sulindac; Survivin; Tongue Neoplasms; Tumor Cells, Cultured	2007
Chemoprevention with special reference to inherited colorectal cancer. Familial cancer, 2008, Volume: 7, Issue:1 Topics: Adenomatous Polyposis Coli; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Ascorbic Acid; Celecoxib; Chemoprevention; Clinical Trials as Topic; Colorectal Neoplasms; Curcumin; Cyclooxygenase 2 Inhibitors; Drug Therapy, Combination; Eflornithine; Humans; Lactones; Pyrazoles; Sulfonamides; Sulfones; Sulindac; Vitamins	2008
Exisulind in combination with celecoxib modulates epidermal growth factor receptor, cyclooxygenase-2, and cyclin D1 against prostate carcinogenesis: in vivo evidence. Clinical cancer research : an official journal of the American Association for Cancer Research, 2007, Oct-01, Volume: 13, Issue:19 Topics: Animals; Anticarcinogenic Agents; Antineoplastic Combined Chemotherapy Protocols; Celecoxib; Cyclin D1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; ErbB Receptors; Humans; Male; Methylnitrosourea; Prostatic Neoplasms; Pyrazoles; Rats; Rats, Wistar; Receptors, Androgen; Sulfonamides; Sulindac; Testosterone	2007
Chemoprevention of arylamine-induced colorectal aberrant crypts. Experimental biology and medicine (Maywood, N.J.), 2008, Volume: 233, Issue:1 Topics: Aminobiphenyl Compounds; Animals; Anticarcinogenic Agents; Celecoxib; Colorectal Neoplasms; Cyclooxygenase Inhibitors; Male; Pyrazoles; Rats; Rats, Inbred F344; Sulfonamides; Sulindac	2008
Drugs to prevent colon cancer show promise, but hurdles remain for chemoprevention. Journal of the National Cancer Institute, 2008, Jun-04, Volume: 100, Issue:11 Topics: Adenoma; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Combined Chemotherapy Protocols; Cardiovascular System; Celecoxib; Colonic Neoplasms; Drug Administration Schedule; Eflornithine; Humans; National Cancer Institute (U.S.); Neoplasm Recurrence, Local; Pyrazoles; Randomized Controlled Trials as Topic; Sulfonamides; Sulindac; United States; United States Food and Drug Administration	2008
Cyclooxygenase inhibitors block uterine tumorigenesis in HMGA1a transgenic mice and human xenografts. Molecular cancer therapeutics, 2008, Volume: 7, Issue:7 Topics: Animals; Celecoxib; Cell Adhesion; Cell Line, Tumor; Cell Proliferation; Cyclooxygenase Inhibitors; Female; HMGA1a Protein; Humans; Mice; Mice, Nude; Mice, Transgenic; Pyrazoles; Sulfonamides; Sulindac; Uterine Neoplasms; Xenograft Model Antitumor Assays	2008
Combination chemoprevention of intestinal carcinogenesis in a murine model of familial adenomatous polyposis. Nutrition and cancer, 2008, Volume: 60 Suppl 1 Topics: Adenoma; Adenomatous Polyposis Coli; Animals; Biogenic Polyamines; Celecoxib; Chemoprevention; Eflornithine; Female; Genes, APC; Intestinal Neoplasms; Intestinal Polyps; Male; Mice; Mice, Inbred C57BL; Pyrazoles; Sulfonamides; Sulindac	2008
Of timing and surrogates: a way forward for cancer chemoprevention. Clinical cancer research : an official journal of the American Association for Cancer Research, 2011, Jun-01, Volume: 17, Issue:11 Topics: Anti-Inflammatory Agents, Non-Steroidal; Anticarcinogenic Agents; Antineoplastic Agents; Biomarkers; Biomarkers, Tumor; Celecoxib; Chemoprevention; Colorectal Neoplasms; Cyclooxygenase 2 Inhibitors; Humans; Pyrazoles; Sulfonamides; Sulindac	2011
Non steroidal anti-inflammatory drugs modulate the physicochemical properties of plasma membrane in experimental colorectal cancer: a fluorescence spectroscopic study. Molecular and cellular biochemistry, 2011, Volume: 358, Issue:1-2 Topics: 1,2-Dimethylhydrazine; 2-Naphthylamine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Blotting, Western; Celecoxib; Cell Membrane; Chemical Phenomena; Colorectal Neoplasms; Cyclooxygenase 2; Laurates; Male; Membrane Fluidity; Microscopy, Fluorescence; Phosphatidylethanolamines; Pyrazoles; Pyrimidinones; Rats; Rats, Sprague-Dawley; Spectrometry, Fluorescence; Sulfonamides; Sulindac; Viscosity	2011
Role of Sulindac and Celecoxib in chemoprevention of colorectal cancer via intrinsic pathway of apoptosis: exploring NHE-1, intracellular calcium homeostasis and Calpain 9. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2012, Volume: 66, Issue:2 Topics: 1,2-Dimethylhydrazine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Calcium; Calpain; Celecoxib; Colorectal Neoplasms; Down-Regulation; Gene Expression Regulation, Neoplastic; Male; Membrane Potential, Mitochondrial; Pyrazoles; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Sodium-Hydrogen Exchangers; Sulfonamides; Sulindac; Up-Regulation	2012
Role of Sulindac and Celecoxib in the regulation of angiogenesis during the early neoplasm of colon: exploring PI3-K/PTEN/Akt pathway to the canonical Wnt/β-catenin signaling. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2012, Volume: 66, Issue:5 Topics: Angiogenesis Inhibitors; Animals; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Blotting, Western; Celecoxib; Colonic Neoplasms; Flow Cytometry; Gene Expression Regulation, Neoplastic; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Male; Neovascularization, Pathologic; Nitric Oxide; Phosphatidylinositol 3-Kinase; Proto-Oncogene Proteins c-akt; PTEN Phosphohydrolase; Pyrazoles; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; Sulfonamides; Sulindac; Wnt Signaling Pathway	2012
Angiostatic properties of sulindac and celecoxib in the experimentally induced inflammatory colorectal cancer. Cell biochemistry and biophysics, 2013, Volume: 66, Issue:2 Topics: 1,2-Dimethylhydrazine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Celecoxib; Colorectal Neoplasms; Cyclooxygenase 2; Dinoprostone; Interferon-gamma; Interleukin-1beta; Interleukin-2; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; NF-kappa B; Nitric Oxide Synthase Type II; Pyrazoles; Rats; Rats, Sprague-Dawley; RNA, Messenger; STAT3 Transcription Factor; Sulfonamides; Sulindac	2013
Sulindac sulfide inhibits sarcoendoplasmic reticulum Ca2+ ATPase, induces endoplasmic reticulum stress response, and exerts toxicity in glioma cells: relevant similarities to and important differences from celecoxib. Journal of neuroscience research, 2013, Volume: 91, Issue:3 Topics: Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Cell Line, Tumor; Endoplasmic Reticulum Chaperone BiP; Endoplasmic Reticulum Stress; Enzyme Inhibitors; Glioma; Humans; Pyrazoles; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Sulfonamides; Sulindac	2013
NSAIDs may regulate EGR-1-mediated induction of reactive oxygen species and non-steroidal anti-inflammatory drug-induced gene (NAG)-1 to initiate intrinsic pathway of apoptosis for the chemoprevention of colorectal cancer. Molecular and cellular biochemistry, 2013, Volume: 378, Issue:1-2 Topics: 1,2-Dimethylhydrazine; Animals; Apoptosis; bcl-X Protein; Celecoxib; Colon; Colorectal Neoplasms; Cyclooxygenase 2 Inhibitors; Early Growth Response Protein 1; Gene Expression; Growth Differentiation Factor 15; Male; Membrane Potential, Mitochondrial; Mitochondria; Molecular Docking Simulation; Pyrazoles; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Sulfonamides; Sulindac	2013
Garcinia benzophenones inhibit the growth of human colon cancer cells and synergize with sulindac sulfide and turmeric. Anti-cancer agents in medicinal chemistry, 2013, Volume: 13, Issue:10 Topics: Adaptor Proteins, Signal Transducing; Antineoplastic Agents, Phytogenic; Benzophenones; Butadienes; Celecoxib; Cell Cycle Proteins; Cell Line, Tumor; Curcuma; Dose-Response Relationship, Drug; Drug Synergism; Endoplasmic Reticulum; Enzyme Inhibitors; Epithelial Cells; Garcinia; Gene Expression Regulation, Neoplastic; Heparin; Humans; Inositol 1,4,5-Trisphosphate Receptors; Mechanistic Target of Rapamycin Complex 1; Mitogen-Activated Protein Kinases; Multiprotein Complexes; Nitriles; Phosphoproteins; Plant Extracts; Pyrazoles; Signal Transduction; Structure-Activity Relationship; Sulfonamides; Sulindac; TOR Serine-Threonine Kinases	2013
Sulindac and Celecoxib regulate cell cycle progression by p53/p21 up regulation to induce apoptosis during initial stages of experimental colorectal cancer. Cell biochemistry and biophysics, 2014, Volume: 68, Issue:2 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Binding Sites; Celecoxib; Cell Cycle Checkpoints; Cell Proliferation; Colorectal Neoplasms; Cyclin-Dependent Kinase Inhibitor p21; Cyclooxygenase 1; Drug Administration Schedule; Male; Membrane Proteins; Molecular Docking Simulation; NF-kappa B; Protein Structure, Tertiary; Pyrazoles; Rats; Rats, Sprague-Dawley; Sulfonamides; Sulindac; Tumor Suppressor Protein p53; Up-Regulation	2014
Sulindac reversal of 15-PGDH-mediated resistance to colon tumor chemoprevention with NSAIDs. Carcinogenesis, 2015, Volume: 36, Issue:2 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Aspirin; Azoxymethane; Carcinogens; Celecoxib; Chemoprevention; Colonic Neoplasms; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Dinoprostone; Hydroxyprostaglandin Dehydrogenases; Inflammation; Intestinal Mucosa; Membrane Proteins; Mice; Mice, Knockout; Pyrazoles; Sulfonamides; Sulindac	2015
Celecoxib and sulindac inhibit TGF-β1-induced epithelial-mesenchymal transition and suppress lung cancer migration and invasion via downregulation of sirtuin 1. Oncotarget, 2016, Aug-30, Volume: 7, Issue:35 Topics: A549 Cells; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Combined Chemotherapy Protocols; Celecoxib; Cell Line, Tumor; Cell Movement; Down-Regulation; Epithelial-Mesenchymal Transition; Gene Expression Regulation, Neoplastic; Gene Silencing; Humans; Lung Neoplasms; Neoplasm Invasiveness; Sirtuin 1; Sulindac; Transforming Growth Factor beta1	2016
Inhibition of cyclooxygenase-2-mediated matriptase activation contributes to the suppression of prostate cancer cell motility and metastasis. Oncogene, 2017, 08-10, Volume: 36, Issue:32 Topics: Animals; Celecoxib; Cell Movement; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Dinoprostone; HEK293 Cells; Humans; Inflammation; Interleukin-2; Male; Membrane Proteins; Mice; Mice, SCID; Neoplasm Invasiveness; Neoplasm Metastasis; Prostatic Neoplasms; Serine Endopeptidases; Sulindac; Tumor Cells, Cultured; Xenograft Model Antitumor Assays	2017
Insight into the Colonic Disposition of Sulindac in Humans. Journal of pharmaceutical sciences, 2021, Volume: 110, Issue:1 Topics: Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Colonic Neoplasms; Colorectal Neoplasms; Humans; Sulindac	2021