celecoxib and sc 58125

celecoxib has been researched along with sc 58125 in 8 studies

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (12.50)18.2507
2000's5 (62.50)29.6817
2010's2 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bertenshaw, SR; Burton, EG; Carter, JS; Cogburn, JN; Collins, PW; Docter, S; Graneto, MJ; Gregory, SA; Isakson, PC; Koboldt, CM; Lee, LF; Malecha, JW; Miyashiro, JM; Penning, TD; Perkins, WE; Rogers, RS; Rogier, DJ; Seibert, K; Talley, JJ; Veenhuizen, AW; Yu, SS; Zhang, YY1
Baurin, N; Chavatte, P; Lesieur, D; Marot, C; Yous, S1
Hagmann, WK1
Chen, CS; Chiu, HC; Gunn, JS; Kulp, SK; Schlesinger, LS; Soni, S; Yang, J1
Meanwell, NA1
Bhardwaj, A; Dzandzi, J; Tietz, O; Valliant, JF; Wuest, F1
Chang, Q; Ding, J; Gong, S1
Hu, Q; Qiu, XW; Wang, ZR; Xu, ZQ; Zhang, J1

Other Studies

8 other study(ies) available for celecoxib and sc 58125

ArticleYear
Synthesis and biological evaluation of the 1,5-diarylpyrazole class of cyclooxygenase-2 inhibitors: identification of 4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benze nesulfonamide (SC-58635, celecoxib).
    Journal of medicinal chemistry, 1997, Apr-25, Volume: 40, Issue:9

    Topics: Animals; Arthritis, Experimental; Arthritis, Rheumatoid; Carrageenan; Celecoxib; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Hyperalgesia; Isoenzymes; Magnetic Resonance Spectroscopy; Male; Membrane Proteins; Molecular Structure; Osteoarthritis; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Rats; Rats, Inbred Lew; Rats, Sprague-Dawley; Structure-Activity Relationship; Sulfonamides

1997
Three-dimensional quantitative structure-activity relationships of cyclo-oxygenase-2 (COX-2) inhibitors: a comparative molecular field analysis.
    Journal of medicinal chemistry, 2001, Sep-27, Volume: 44, Issue:20

    Topics: Benzene Derivatives; Binding Sites; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Cyclopentanes; Imidazoles; Isoenzymes; Isoxazoles; Models, Molecular; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Pyrroles; Quantitative Structure-Activity Relationship; Spiro Compounds; Thiophenes

2001
The many roles for fluorine in medicinal chemistry.
    Journal of medicinal chemistry, 2008, Aug-14, Volume: 51, Issue:15

    Topics: Animals; Chemistry, Pharmaceutical; Enzyme Inhibitors; Fluorine; Fluorine Compounds; Humans; Protein Binding; Stereoisomerism

2008
Pharmacological exploitation of an off-target antibacterial effect of the cyclooxygenase-2 inhibitor celecoxib against Francisella tularensis.
    Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:7

    Topics: Animals; Celecoxib; Cell Line; Cell Survival; Cyclooxygenase 2 Inhibitors; Francisella tularensis; Humans; Lactones; Mice; Microbial Sensitivity Tests; Pyrazoles; Sulfonamides; Sulfones

2009
Synopsis of some recent tactical application of bioisosteres in drug design.
    Journal of medicinal chemistry, 2011, Apr-28, Volume: 54, Issue:8

    Topics: Cytochrome P-450 Enzyme System; Drug Design

2011
Design and synthesis of [(125)I]Pyricoxib: A novel (125)I-labeled cyclooxygenase-2 (COX-2) inhibitors.
    Bioorganic & medicinal chemistry letters, 2016, Mar-15, Volume: 26, Issue:6

    Topics: Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Dose-Response Relationship, Drug; Drug Design; Humans; Iodine Radioisotopes; Molecular Docking Simulation; Molecular Structure; Pyrimidines; Structure-Activity Relationship; Sulfones

2016
Inhibitory effects of Celecoxib and Sc-58125 on proliferation of human carcinoma of larynx Hep-2 in vitro.
    Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban, 2005, Volume: 25, Issue:2

    Topics: Antineoplastic Agents; Apoptosis; Celecoxib; Cell Proliferation; Cyclooxygenase 2 Inhibitors; Dose-Response Relationship, Drug; Humans; Laryngeal Neoplasms; Pyrazoles; Sulfonamides; Tumor Cells, Cultured

2005
[Effects of selective cyclooxygenase-2 inhibitor on proliferation and apoptosis of human bladder cancer cell line T24].
    Ai zheng = Aizheng = Chinese journal of cancer, 2007, Volume: 26, Issue:4

    Topics: Apoptosis; bcl-2-Associated X Protein; Celecoxib; Cell Line, Tumor; Cell Proliferation; Cyclooxygenase 2 Inhibitors; Flow Cytometry; Humans; Indomethacin; Inhibitory Concentration 50; Proto-Oncogene Proteins c-bcl-2; Pyrazoles; Reverse Transcriptase Polymerase Chain Reaction; Sulfonamides; Urinary Bladder Neoplasms

2007