celecoxib and sc 560

celecoxib has been researched along with sc 560 in 51 studies

Research

Studies (51)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	2 (3.92)	18.2507
2000's	26 (50.98)	29.6817
2010's	22 (43.14)	24.3611
2020's	1 (1.96)	2.80

Authors

Authors	Studies
Bertenshaw, SR; Burton, EG; Carter, JS; Cogburn, JN; Collins, PW; Docter, S; Graneto, MJ; Gregory, SA; Isakson, PC; Koboldt, CM; Lee, LF; Malecha, JW; Miyashiro, JM; Penning, TD; Perkins, WE; Rogers, RS; Rogier, DJ; Seibert, K; Talley, JJ; Veenhuizen, AW; Yu, SS; Zhang, YY	1
Casini, A; Heine, A; Klebe, G; Kuhn, D; Scozzafava, A; Supuran, CT; Weber, A	1
Bilter, GK; Dias, J; Huang, Z; Keon, BH; Lamerdin, J; MacDonald, ML; Michnick, SW; Minami, T; Owens, S; Shang, Z; Westwick, JK; Yu, H	1
Abraham, WM; Albert, L; Behnke, ML; Chen, L; Clark, JD; Donahue, F; Foley, MA; Goodwin, DG; Hegen, M; Hu, B; Hu, Y; Ipek, M; Keith, J; Kirincich, SJ; Ku, MS; Lee, KL; McKew, JC; Michalak, R; Murphy, EA; Nickerson-Nutter, CL; Ramarao, MK; Shen, MW; Sum, FW; Tam, S; Thakker, P; Thomason, J; Williams, C; Wooder, L; Wu, K; Xu, X	1
Chen, L; Clark, JD; Goodwin, DG; Lee, KL; McKew, JC; Murphy, EA; Nickerson-Nutter, C; Shen, MW; Tam, S; Wang, W; Xu, X; Zhang, W	1
Blobaum, AL; Crews, BC; Daniel, CM; Ghebreselasie, K; Kingsley, PJ; Liedtke, AJ; Marnett, LJ	1
Buscató, E; Deckmann, K; Geisslinger, G; Grösch, S; Proschak, E; Rörsch, F; Schneider, G; Schubert-Zsilavecz, M	1
Amini, M; Amirhamzeh, A; Assadieskandar, A; Ostad, SN; Ozadali, K; Salehi, M; Shafiee, A	1
Ferreiros, N; Geisslinger, G; Grösch, S; Hanke, T; Proschak, E; Rörsch, F; Schneider, G; Schubert-Zsilavecz, M; Thieme, TM	1
Lavecchia, A; Malerba, P; Perrone, MG; Scilimati, A; Vitale, P	1
Alfonso, S; Anzini, M; Biava, M; Consalvi, S; Di Capua, A; Di Cesare Mannelli, L; Ghelardini, C; La Motta, C; Pirolli, A; Poce, G; Ragno, R; Sabatino, M; Sartini, S	1
Chaturbhuj, GU; Goyal, SN; Indalkar, KS; Khatri, CK; Patil, CR	1
Chung, HY; Hong, J; Ju, Z; Jung, JH; Kim, S; La Kim, E; Moon, HR; Su, M	1
Bhardwaj, A; Kaur, J; Wuest, F	1
Isakson, PC; Koboldt, CM; Masferrer, JL; Muhammad, J; Seibert, K; Shaffer, A; Smith, CJ; Talley, JJ; Zhang, Y; Zweifel, BS	1
McKnight, W; Reuter, BK; Vergnolle, N; Wallace, JL	1
Gierse, JK; Isakson, PC; Kiefer, JR; Koboldt, CM; Kurumbail, RG; Moreland, KT; Seibert, K; Walker, MC	1
Bräutigam, L; Geisslinger, G; Grösch, S; Niederberger, E; Tegeder, I	1
Bräutigam, L; Geisslinger, G; Niederberger, E; Tegeder, I; Vetter, G	1
Altuna, R; Arroyo, V; Clària, J; Jiménez, W; Koki, AT; López-Parra, M; Masferrer, JL; Planagumà, A; Rivera, F; Rodés, J; Titos, E; Woerner, BM	1
Nozaki-Taguchi, N; Yamamoto, T	1
Chen, N; Reiss, CS; Restivo, A	1
Dunn, AJ; Swiergiel, AH	1
Carter, J; Gierse, J; Hood, B; Isakson, P; Kiefer, J; Koboldt, C; Kurumbail, R; Marnett, L; Monahan, J; Moreland, K; Pawlitz, J; Pierce, J; Rowlinson, S; Seibert, K; Stegeman, R; Stevens, A; Talley, J; Walker, M	1
Akunda, JK; Langenbach, R; Lao, HC; Lee, CA; Sessoms, AR; Slade, RM	1
Cartwright, C; Chan, D; Felix, E; Fischer, SM; Klein, RD; Madden, T; Menter, DG; Newman, RA; Yang, P	1
Fiorucci, S; Hollenberg, MD; von der Weid, PY; Wallace, JL	1
Amrite, AC; Ayalasomayajula, SP; Kompella, UB	1
Doi, Y; Ito, S; Minami, T; Muratani, T; Nishimura, W; Nishizawa, M	1
Adami, M; Coppelli, G; Coruzzi, G; Giovannini, E; Guaita, E; Menozzi, A; Pozzoli, C	1
Bishop-Bailey, D; Mitchell, JA; Vojnovic, I; Warner, TD	1
Arthur, HM; Borthwick, GM; Burn, J; Johnson, AS; Partington, M; Wilson, R	1
Bertini, S; Bonardi, S; Coruzzi, G; Giovannini, E; Grandi, D; Menozzi, A; Pozzoli, C; Solenghi, E; Vasina, V	1
Aoi, Y; Hayashi, S; Kato, S; Nishio, H; Okayama, M; Takeuchi, K	1
Lee, IO; Seo, Y	1
Bertini, S; Dacasto, M; Giantin, M; Gobbetti, T; Lopparelli, RM; Menozzi, A; Passeri, B; Poli, E; Pozzoli, C; Zullian, C	1
Cara, DC; Francischi, JN; Klein, A; Menezes, GB; Pereira-Silva, PE; Rezende, RM	1
Bingaman, DP; Clark, ML; Penn, JS; Yang, R; Yanni, SE	1
Bjarnason, IT; Hotz-Behofsits, C; Simpson, RJ; Walley, M	1
Bradbury, JA; Carey, MA; Germolec, DR; Graves, JP; Rebolloso, YD; Zeldin, DC	1
Jiang, HR; Li, W; Liu, ML; Wang, J; Xu, XL; Zhai, LY; Zhang, J	1
Brzozowski, T; Konturek, SJ; Kwiecien, S; Mazurkiewicz-Janik, M; Pajdo, R; Pawlik, M; Pawlik, WW; Ptak-Belowska, A; Sliwowski, Z	1
Calvello, R; Carbone, ML; Cianciulli, A; Malerba, P; Panaro, MA; Perrone, MG; Scilimati, A; Vitale, P	1
Cai, JH; Li, W; Tang, YX; Wan, L; Zhang, J	1
Akiba, Y; Amagase, K; Ebara, S; Satoh, H; Takeuchi, K	1
Cai, J; Li, W; Liu, M; Tang, Y; Zhai, L; Zhang, J	1
Cai, KQ; Smedberg, J; Smith, ER; Xu, XX; Yang, WL; Yeasky, T	1
Kanamoto, R; Kaneko, K; Lazarus, M; Miyazaki, Y; Mizushige, T; Ohinata, K; Urade, Y; Yoshikawa, M	1
Li, C; Raikwar, NS; Santillan, DA; Santillan, MK; Thomas, CP	1
Adamski, J; Brzozowski, T; Kwiecien, S; Magierowska, K; Magierowski, M; Mazur-Bialy, AI; Pajdo, R; Sliwowski, Z; Surmiak, M	1
Chang, CC; Chuang, CL; Hsieh, HG; Huang, HC; Lee, FY; Lee, SD; Lee, WS	1

Other Studies

51 other study(ies) available for celecoxib and sc 560

Article	Year
Synthesis and biological evaluation of the 1,5-diarylpyrazole class of cyclooxygenase-2 inhibitors: identification of 4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benze nesulfonamide (SC-58635, celecoxib). Journal of medicinal chemistry, 1997, Apr-25, Volume: 40, Issue:9 Topics: Animals; Arthritis, Experimental; Arthritis, Rheumatoid; Carrageenan; Celecoxib; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Hyperalgesia; Isoenzymes; Magnetic Resonance Spectroscopy; Male; Membrane Proteins; Molecular Structure; Osteoarthritis; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Rats; Rats, Inbred Lew; Rats, Sprague-Dawley; Structure-Activity Relationship; Sulfonamides	1997
Unexpected nanomolar inhibition of carbonic anhydrase by COX-2-selective celecoxib: new pharmacological opportunities due to related binding site recognition. Journal of medicinal chemistry, 2004, Jan-29, Volume: 47, Issue:3 Topics: Animals; Binding Sites; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Celecoxib; Crystallography, X-Ray; Cyclooxygenase 2; Intraocular Pressure; Isoenzymes; Isoxazoles; Kinetics; Lactones; Models, Molecular; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Rabbits; Structure-Activity Relationship; Sulfonamides; Sulfones	2004
Identifying off-target effects and hidden phenotypes of drugs in human cells. Nature chemical biology, 2006, Volume: 2, Issue:6 Topics: Bacterial Proteins; Cell Line; Cell Proliferation; Cluster Analysis; Drug Design; Drug Evaluation, Preclinical; Genetics; Humans; Luminescent Proteins; Molecular Structure; Phenotype; Recombinant Fusion Proteins; Signal Transduction; Structure-Activity Relationship	2006
Indole cytosolic phospholipase A2 alpha inhibitors: discovery and in vitro and in vivo characterization of 4-{3-[5-chloro-2-(2-{[(3,4-dichlorobenzyl)sulfonyl]amino}ethyl)-1-(diphenylmethyl)-1H-indol-3-yl]propyl}benzoic acid, efipladib. Journal of medicinal chemistry, 2008, Jun-26, Volume: 51, Issue:12 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Benzoates; Biological Availability; Bronchoconstriction; Calorimetry; Carrageenan; Cell Line; Cyclooxygenase 2 Inhibitors; Edema; Group IV Phospholipases A2; Humans; In Vitro Techniques; Isoenzymes; Male; Mice; Protein Binding; Rats; Rats, Sprague-Dawley; Sheep; Structure-Activity Relationship; Sulfonamides	2008
Reactions of functionalized sulfonamides: application to lowering the lipophilicity of cytosolic phospholipase A2alpha inhibitors. Journal of medicinal chemistry, 2009, Feb-26, Volume: 52, Issue:4 Topics: Animals; Enzyme Inhibitors; Group IV Phospholipases A2; Hydrophobic and Hydrophilic Interactions; Rats; Structure-Activity Relationship; Sulfides; Sulfonamides	2009
Cyclooxygenase-1-selective inhibitors based on the (E)-2'-des-methyl-sulindac sulfide scaffold. Journal of medicinal chemistry, 2012, Mar-08, Volume: 55, Issue:5 Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Cyclooxygenase 1; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Drug Screening Assays, Antitumor; Female; Humans; Hydrophobic and Hydrophilic Interactions; Mice; Sheep; Stereoisomerism; Structure-Activity Relationship; Sulindac	2012
Structure-activity relationship of nonacidic quinazolinone inhibitors of human microsomal prostaglandin synthase 1 (mPGES 1). Journal of medicinal chemistry, 2012, Apr-26, Volume: 55, Issue:8 Topics: Animals; Biological Availability; Cell Line, Tumor; Cell Survival; Enzyme Inhibitors; HeLa Cells; Humans; Intramolecular Oxidoreductases; Mice; Microsomes; Prostaglandin-E Synthases; Quinazolinones; Structure-Activity Relationship	2012
Synthesis, cyclooxygenase inhibitory effects, and molecular modeling study of 4-aryl-5-(4-(methylsulfonyl)phenyl)-2-alkylthio and -2-alkylsulfonyl-1H-imidazole derivatives. Bioorganic & medicinal chemistry, 2013, Apr-15, Volume: 21, Issue:8 Topics: Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Humans; Imidazoles; Models, Molecular; Structure-Activity Relationship	2013
Synthesis and pharmacological characterization of benzenesulfonamides as dual species inhibitors of human and murine mPGES-1. Bioorganic & medicinal chemistry, 2013, Dec-15, Volume: 21, Issue:24 Topics: Animals; Benzenesulfonamides; Cell Survival; Dose-Response Relationship, Drug; Enzyme Inhibitors; HeLa Cells; Humans; Intramolecular Oxidoreductases; Ligands; Mice; Molecular Structure; NIH 3T3 Cells; Prostaglandin-E Synthases; Structure-Activity Relationship; Sulfonamides	2013
Selective COX-1 inhibition as a target of theranostic novel diarylisoxazoles. European journal of medicinal chemistry, 2014, Mar-03, Volume: 74 Topics: Cell Line, Tumor; Cyclooxygenase 1; Cyclooxygenase Inhibitors; Drug Design; Gas Chromatography-Mass Spectrometry; Humans; Inhibitory Concentration 50; Isoxazoles; Magnetic Resonance Spectroscopy; Molecular Docking Simulation; Spectroscopy, Fourier Transform Infrared; Structure-Activity Relationship	2014
Synthesis, biological evaluation and docking analysis of a new series of methylsulfonyl and sulfamoyl acetamides and ethyl acetates as potent COX-2 inhibitors. Bioorganic & medicinal chemistry, 2015, Feb-15, Volume: 23, Issue:4 Topics: Acetamides; Acetates; Analgesics; Animals; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Drug Design; Humans; Methylation; Mice; Molecular Docking Simulation; Rats, Sprague-Dawley; Rats, Wistar; Structure-Activity Relationship; Sulfur Compounds	2015
Novel 2-phenyl-4,5,6,7-tetrahydro[b]benzothiophene analogues as selective COX-2 inhibitors: Design, synthesis, anti-inflammatory evaluation, and molecular docking studies. Bioorganic & medicinal chemistry letters, 2017, 04-15, Volume: 27, Issue:8 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Cyclooxygenase 2 Inhibitors; Drug Design; Edema; Mice; Molecular Docking Simulation; Rats; RAW 264.7 Cells; Thiophenes	2017
Design of balanced COX inhibitors based on anti-inflammatory and/or COX-2 inhibitory ascidian metabolites. European journal of medicinal chemistry, 2019, Oct-15, Volume: 180 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Survival; Cells, Cultured; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Dose-Response Relationship, Drug; Drug Design; Humans; Mice; Models, Molecular; Molecular Structure; RAW 264.7 Cells; Sheep; Structure-Activity Relationship; Urochordata	2019
Development of Fluorescence Imaging Probes for Labeling COX-1 in Live Ovarian Cancer Cells. ACS medicinal chemistry letters, 2021, May-13, Volume: 12, Issue:5 Topics:	2021
Pharmacological analysis of cyclooxygenase-1 in inflammation. Proceedings of the National Academy of Sciences of the United States of America, 1998, Oct-27, Volume: 95, Issue:22 Topics: Animals; Arthritis, Experimental; Blood Platelets; Carrageenan; Celecoxib; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Edema; Hyperalgesia; Indomethacin; Inflammation; Isoenzymes; Male; Membrane Proteins; Models, Biological; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Sulfonamides; Thromboxane B2	1998
NSAID-induced gastric damage in rats: requirement for inhibition of both cyclooxygenase 1 and 2. Gastroenterology, 2000, Volume: 119, Issue:3 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Cell Adhesion; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Gastric Mucosa; Isoenzymes; Ketorolac; Leukocytes; Male; Membrane Proteins; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Pyrazoles; Rats; Rats, Wistar; Regional Blood Flow; Stomach; Sulfonamides; Thiophenes	2000
A three-step kinetic mechanism for selective inhibition of cyclo-oxygenase-2 by diarylheterocyclic inhibitors. The Biochemical journal, 2001, Aug-01, Volume: 357, Issue:Pt 3 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Binding, Competitive; Celecoxib; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Isoenzymes; Isoxazoles; Kinetics; Meloxicam; Mice; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Sheep; Sulfonamides; Thiazines; Thiazoles	2001
COX-2 independent induction of cell cycle arrest and apoptosis in colon cancer cells by the selective COX-2 inhibitor celecoxib. FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2001, Volume: 15, Issue:14 Topics: Animals; Apoptosis; Blotting, Western; Caco-2 Cells; Celecoxib; Cell Cycle; Cell Cycle Proteins; Cell Division; Cell Survival; Colonic Neoplasms; Cyclin-Dependent Kinase Inhibitor p21; Cyclin-Dependent Kinase Inhibitor p27; Cyclins; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; HT29 Cells; Humans; Isoenzymes; Membrane Proteins; Mice; Mice, Nude; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Sulfonamides; Tumor Cells, Cultured; Tumor Suppressor Proteins; Xenograft Model Antitumor Assays	2001
Effects of selective COX-1 and -2 inhibition on formalin-evoked nociceptive behaviour and prostaglandin E(2) release in the spinal cord. Journal of neurochemistry, 2001, Volume: 79, Issue:4 Topics: Animals; Behavior, Animal; Celecoxib; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Formaldehyde; Isoenzymes; Membrane Proteins; Microdialysis; Pain; Pain Measurement; Posterior Horn Cells; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Rats; Rats, Sprague-Dawley; RNA, Messenger; Spinal Cord; Sulfonamides	2001
Cyclooxygenase-1 derived prostaglandins are involved in the maintenance of renal function in rats with cirrhosis and ascites. British journal of pharmacology, 2002, Volume: 135, Issue:4 Topics: Animals; Ascites; Blotting, Western; Carbon Tetrachloride Poisoning; Celecoxib; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Diuretics; Furosemide; Immunohistochemistry; Isoenzymes; Kidney; Liver Cirrhosis, Experimental; Male; Membrane Proteins; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Pyrazoles; Rats; Rats, Wistar; Sulfonamides; Water	2002
The role of cyclooxygenase-1 and -2 in the rat formalin test. Anesthesia and analgesia, 2002, Volume: 94, Issue:4 Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Formaldehyde; Indomethacin; Injections, Spinal; Isoenzymes; Male; Membrane Proteins; Neural Conduction; Pain; Pain Measurement; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Rats; Rats, Sprague-Dawley; Sulfonamides	2002
Selective inhibition of COX-2 is beneficial to mice infected intranasally with VSV. Prostaglandins & other lipid mediators, 2002, Volume: 67, Issue:2 Topics: Animals; Arachidonate 5-Lipoxygenase; Blotting, Western; Celecoxib; Central Nervous System; Cyclooxygenase 1; Cyclooxygenase 2; Interferon-gamma; Interleukin-12; Isoenzymes; Membrane Proteins; Mice; Neutrophils; Nitric Oxide Synthase; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Reverse Transcriptase Polymerase Chain Reaction; Rhabdoviridae Infections; Sulfonamides; Time Factors; Vesicular stomatitis Indiana virus	2002
Distinct roles for cyclooxygenases 1 and 2 in interleukin-1-induced behavioral changes. The Journal of pharmacology and experimental therapeutics, 2002, Volume: 302, Issue:3 Topics: Animals; Behavior, Animal; Body Weight; Celecoxib; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Eating; Interleukin-1; Isoenzymes; Lipopolysaccharides; Male; Membrane Proteins; Mice; Mice, Knockout; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Sulfonamides	2002
Mechanism of inhibition of novel COX-2 inhibitors. Advances in experimental medicine and biology, 2002, Volume: 507 Topics: Celecoxib; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Humans; Isoenzymes; Isoxazoles; Kinetics; Membrane Proteins; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Recombinant Proteins; Sulfonamides; Time Factors	2002
Genetic deficiency or pharmacological inhibition of cyclooxygenase-1 or -2 induces mouse keratinocyte differentiation in vitro and in vivo. FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2004, Volume: 18, Issue:1 Topics: Animals; Antineoplastic Agents; Apoptosis; Celecoxib; Cell Differentiation; Cells, Cultured; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Epidermal Cells; Isoenzymes; Keratinocytes; Keratins; Membrane Proteins; Mice; Mice, Knockout; Prostaglandin-Endoperoxide Synthases; Protein Precursors; Pyrazoles; Skin Neoplasms; Sulfonamides	2004
Formation and antiproliferative effect of prostaglandin E(3) from eicosapentaenoic acid in human lung cancer cells. Journal of lipid research, 2004, Volume: 45, Issue:6 Topics: Alprostadil; Celecoxib; Cell Death; Cell Line, Tumor; Cell Proliferation; Cyclooxygenase 2; DNA; Eicosapentaenoic Acid; Humans; Lung Neoplasms; Membrane Proteins; Microscopy, Fluorescence; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Sulfonamides	2004
Aspirin-triggered, cyclooxygenase-2-dependent lipoxin synthesis modulates vascular tone. Circulation, 2004, Sep-07, Volume: 110, Issue:10 Topics: Acetylcholine; Animals; Aorta; Aspirin; Blood Pressure; Celecoxib; Cyclooxygenase 2 Inhibitors; Endothelium, Vascular; Hydroxyurea; Lipoxins; Lipoxygenase Inhibitors; Male; Mesenteric Arteries; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitroarginine; Oligopeptides; Pyrazoles; Rats; Rats, Sprague-Dawley; Rats, Wistar; Receptors, Lipoxin; Sulfonamides; Vascular Resistance; Vasodilation; Vasodilator Agents	2004
Inhibition of cyclooxygenase-2, but not cyclooxygenase-1, reduces prostaglandin E2 secretion from diabetic rat retinas. European journal of pharmacology, 2004, Sep-13, Volume: 498, Issue:1-3 Topics: Animals; Celecoxib; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Dinoprostone; In Vitro Techniques; Membrane Proteins; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Rats; Rats, Sprague-Dawley; Retina; Sulfonamides; Time Factors	2004
Preemptive analgesia by zaltoprofen that inhibits bradykinin action and cyclooxygenase in a post-operative pain model. Neuroscience research, 2005, Volume: 51, Issue:4 Topics: Administration, Oral; Analgesia; Animals; Anti-Inflammatory Agents, Non-Steroidal; Benzopyrans; Bradykinin; Celecoxib; Cyclooxygenase Inhibitors; Injections, Spinal; Male; Mice; Pain, Postoperative; Propionates; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Receptor, Bradykinin B2; RNA, Messenger; Sulfonamides	2005
Effects of cyclooxygenase-1 and -2 inhibition on gastric acid secretion and cardiovascular functions in rats. Pharmacology, 2006, Volume: 76, Issue:2 Topics: Animals; Blood Pressure; Celecoxib; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Gastric Acid; Heart Rate; Hemodynamics; Indomethacin; Male; Pentagastrin; Pyrazoles; Rats; Rats, Wistar; Sulfonamides; Vagotomy	2006
Influence of plasma protein on the potencies of inhibitors of cyclooxygenase-1 and -2. FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2006, Volume: 20, Issue:3 Topics: Aspirin; Blood Platelets; Blood Proteins; Calcimycin; Calcium; Celecoxib; Cell Line; Cerebrospinal Fluid Proteins; Cyclooxygenase 1; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Diclofenac; Dinoprostone; Humans; Indomethacin; Ionophores; Lactones; Meloxicam; Naproxen; Organ Specificity; Organic Chemicals; Protein Binding; Pyrazoles; Sodium Salicylate; Sulfonamides; Sulfones; Synovial Fluid; Thiazines; Thiazoles; Thromboxane A2	2006
Therapeutic levels of aspirin and salicylate directly inhibit a model of angiogenesis through a Cox-independent mechanism. FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2006, Volume: 20, Issue:12 Topics: Antineoplastic Agents; Aspirin; Celecoxib; Cell Line; Cell Proliferation; Cell Survival; Cyclooxygenase Inhibitors; Endothelial Cells; Humans; Neovascularization, Physiologic; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Salicylic Acid; Sulfonamides	2006
Intestinal effects of nonselective and selective cyclooxygenase inhibitors in the rat. European journal of pharmacology, 2006, Dec-15, Volume: 552, Issue:1-3 Topics: Administration, Oral; Analysis of Variance; Animals; Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Enterobacteriaceae; Ibuprofen; Indomethacin; Intestinal Mucosa; Intestine, Small; Lipid Peroxidation; Male; Mucins; Peroxidase; Pyrazoles; Rats; Rats, Wistar; Sulfonamides	2006
Aggravation by selective COX-1 and COX-2 inhibitors of dextran sulfate sodium (DSS)-induced colon lesions in rats. Digestive diseases and sciences, 2007, Volume: 52, Issue:9 Topics: Animals; Cardiovascular Diseases; Celecoxib; Colitis, Ulcerative; Colon; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Dextran Sulfate; Dinoprostone; Disease Models, Animal; Gene Expression; Indomethacin; Male; Peroxidase; Plasma Substitutes; Pyrazoles; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Spectrophotometry; Sulfonamides; Treatment Outcome	2007
The effects of intrathecal cyclooxygenase-1, cyclooxygenase-2, or nonselective inhibitors on pain behavior and spinal Fos-like immunoreactivity. Anesthesia and analgesia, 2008, Volume: 106, Issue:3 Topics: Animals; Behavior, Animal; Celecoxib; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Formaldehyde; Hyperalgesia; Immunohistochemistry; Injections, Spinal; Ketorolac; Male; Membrane Proteins; Pain; Pain Measurement; Posterior Horn Cells; Proto-Oncogene Proteins c-fos; Pyrazoles; Rats; Rats, Sprague-Dawley; Sulfonamides; Time Factors	2008
Effects of nonselective and selective cyclooxygenase inhibitors on small intestinal motility in the horse. Research in veterinary science, 2009, Volume: 86, Issue:1 Topics: Animals; Celecoxib; Clonixin; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Gastrointestinal Motility; Histocytochemistry; Horses; In Vitro Techniques; Indomethacin; Intestine, Small; Male; Pyrazoles; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sulfonamides	2009
Differential involvement of cyclooxygenase isoforms in neutrophil migration in vivo and in vitro. European journal of pharmacology, 2008, Nov-19, Volume: 598, Issue:1-3 Topics: Animals; Celecoxib; Cell Adhesion; Cell Movement; Cell Separation; Chemotaxis, Leukocyte; Cyclooxygenase 1; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Data Interpretation, Statistical; Endothelium, Vascular; Female; Indomethacin; Isoenzymes; Male; Mice; Neutrophil Infiltration; Neutrophils; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Rats; Rats, Sprague-Dawley; Sulfonamides	2008
The effects of nepafenac and amfenac on retinal angiogenesis. Brain research bulletin, 2010, Feb-15, Volume: 81, Issue:2-3 Topics: Analysis of Variance; Animals; Animals, Newborn; Anti-Inflammatory Agents, Non-Steroidal; Benzeneacetamides; Celecoxib; Cell Proliferation; Cyclooxygenase Inhibitors; Dinoprostone; Disease Models, Animal; Dose-Response Relationship, Drug; Epithelial Cells; Gene Expression Regulation; Humans; Neuroglia; Oxygen; Phenylacetates; Prostaglandins; Pyrazoles; Rats; Rats, Long-Evans; Rats, Sprague-Dawley; Retina; Retinal Neovascularization; Retinal Vessels; Sulfonamides; Vascular Endothelial Growth Factor A	2010
Role of COX-2 in nonsteroidal anti-inflammatory drug enteropathy in rodents. Scandinavian journal of gastroenterology, 2010, Volume: 45, Issue:7-8 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Cyclooxygenase 2; Dinoprostone; Flurbiprofen; Inflammation; Intestine, Small; Male; Mice; Pyrazoles; Rats; Rats, Sprague-Dawley; Sulfonamides	2010
Pharmacologic inhibition of COX-1 and COX-2 in influenza A viral infection in mice. PloS one, 2010, Jul-15, Volume: 5, Issue:7 Topics: Animals; Celecoxib; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Female; Influenza A virus; Mice; Orthomyxoviridae Infections; Pyrazoles; Sulfonamides	2010
Combined effects of cyclooxygenase-1 and cyclooxygenase-2 selective inhibitors on ovarian carcinoma in vivo. International journal of molecular sciences, 2011, Jan-18, Volume: 12, Issue:1 Topics: Animals; Celecoxib; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Female; Humans; Mice; Ovarian Neoplasms; Pyrazoles; Sulfonamides; Xenograft Model Antitumor Assays	2011
Nitric oxide (NO)-releasing aspirin exhibits a potent esophagoprotection in experimental model of acute reflux esophagitis. Role of nitric oxide and proinflammatory cytokines. Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 2011, Volume: 62, Issue:1 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Celecoxib; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Cytokines; Dinoprostone; Esophagitis, Peptic; Esophagus; Gastric Acid; Humans; Indomethacin; Male; Nitric Oxide; Nitric Oxide Donors; Nitroglycerin; Pyrazoles; Rats; Rats, Wistar; RNA, Messenger; Sulfonamides	2011
Novel selective COX-1 inhibitors suppress neuroinflammatory mediators in LPS-stimulated N13 microglial cells. Pharmacological research, 2012, Volume: 65, Issue:1 Topics: Animals; Aspirin; Celecoxib; Cell Line; Cell Survival; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Dose-Response Relationship, Drug; Down-Regulation; Etoricoxib; I-kappa B Proteins; Inflammation Mediators; Intramolecular Oxidoreductases; Lipopolysaccharides; Membrane Proteins; Mice; Microglia; NF-kappa B; NF-KappaB Inhibitor alpha; Nitric Oxide; Nitric Oxide Synthase Type II; Phosphorylation; Prostaglandin-E Synthases; Pyrazoles; Pyridines; RNA, Messenger; Sulfonamides; Sulfones	2012
Effects of cyclooxygenase inhibitors in combination with taxol on expression of cyclin D1 and Ki-67 in a xenograft model of ovarian carcinoma. International journal of molecular sciences, 2012, Volume: 13, Issue:8 Topics: Animals; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Celecoxib; Cell Proliferation; Cyclin D1; Cyclooxygenase Inhibitors; Female; Humans; Immunoenzyme Techniques; Ki-67 Antigen; Mice; Mice, Nude; Ovarian Neoplasms; Paclitaxel; Pyrazoles; Sulfonamides; Tumor Cells, Cultured; Xenograft Model Antitumor Assays	2012
Cyclooxygenase (COX)-1 and COX-2 both play an important role in the protection of the duodenal mucosa in cats. The Journal of pharmacology and experimental therapeutics, 2013, Volume: 344, Issue:1 Topics: Animals; Blotting, Western; Cats; Celecoxib; Cimetidine; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Diet; Dinoprostone; Duodenal Diseases; Duodenum; Female; Histamine H2 Antagonists; Immunohistochemistry; Intestinal Mucosa; Male; Pyrazoles; Sulfonamides	2013
Antitumor properties of taxol in combination with cyclooxygenase-1 and cyclooxygenase-2 selective inhibitors on ovarian tumor growth in vivo. Oncology research, 2012, Volume: 20, Issue:2-3 Topics: Animals; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Celecoxib; Cell Proliferation; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Female; Humans; Immunoenzyme Techniques; In Situ Nick-End Labeling; Mice; Mice, Nude; Ovarian Neoplasms; Paclitaxel; Pyrazoles; Sulfonamides; Tumor Cells, Cultured	2012
Cyclooxygenase-1 inhibition prolongs postnatal ovarian follicle lifespan in mice. Biology of reproduction, 2013, Volume: 89, Issue:4 Topics: Aging; Animals; Celecoxib; Crosses, Genetic; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Female; Indomethacin; Membrane Proteins; Menopause; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Mutant Strains; Ovarian Follicle; Primary Ovarian Insufficiency; Pyrazoles; Random Allocation; Sexual Development; Sulfonamides	2013
δ-Opioid receptor activation stimulates normal diet intake but conversely suppresses high-fat diet intake in mice. American journal of physiology. Regulatory, integrative and comparative physiology, 2014, Feb-15, Volume: 306, Issue:4 Topics: Analgesics, Opioid; Animals; Celecoxib; Cyclooxygenase Inhibitors; Diet, High-Fat; Eating; Enkephalin, D-Penicillamine (2,5)-; Male; Mice; Pyrazoles; Receptors, Opioid, delta; Receptors, Prostaglandin; Sulfonamides	2014
Aspirin inhibits expression of sFLT1 from human cytotrophoblasts induced by hypoxia, via cyclo-oxygenase 1. Placenta, 2015, Volume: 36, Issue:4 Topics: Adult; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Celecoxib; Cell Hypoxia; Cell Line; Cells, Cultured; Chlorocebus aethiops; COS Cells; Cyclooxygenase 1; Cyclooxygenase Inhibitors; Female; Gene Expression Regulation, Developmental; Humans; Pre-Eclampsia; Pregnancy; Pyrazoles; Recombinant Proteins; Solubility; Trophoblasts; Vascular Endothelial Growth Factor Receptor-1	2015
The Protective Role of Carbon Monoxide (CO) Produced by Heme Oxygenases and Derived from the CO-Releasing Molecule CORM-2 in the Pathogenesis of Stress-Induced Gastric Lesions: Evidence for Non-Involvement of Nitric Oxide (NO). International journal of molecular sciences, 2016, Mar-24, Volume: 17, Issue:4 Topics: Animals; Carbon Monoxide; Celecoxib; Cyclooxygenase 2; Gastric Mucosa; Heme Oxygenase (Decyclizing); Hemin; Hypoxia-Inducible Factor 1, alpha Subunit; Indomethacin; Male; Nitric Oxide; Nitric Oxide Synthase Type II; Nitroarginine; Organometallic Compounds; Protoporphyrins; Pyrazoles; Rats; Rats, Wistar; RNA, Messenger; Stress, Physiological	2016
Selective cyclooxygenase inhibition by SC-560 improves hepatopulmonary syndrome in cirrhotic rats. PloS one, 2017, Volume: 12, Issue:6 Topics: Animals; Celecoxib; Cyclooxygenase 1; Cyclooxygenase Inhibitors; Disease Models, Animal; Down-Regulation; Hemodynamics; Hepatopulmonary Syndrome; Liver; Liver Cirrhosis; Lung; Male; NF-kappa B; Pyrazoles; Rats; Rats, Sprague-Dawley; Tumor Necrosis Factor-alpha; Vascular Endothelial Growth Factor A	2017