celecoxib and sc 560
celecoxib has been researched along with sc 560 in 51 studies
Research
Studies (51)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (3.92) | 18.2507 |
| 2000's | 26 (50.98) | 29.6817 |
| 2010's | 22 (43.14) | 24.3611 |
| 2020's | 1 (1.96) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Bertenshaw, SR; Burton, EG; Carter, JS; Cogburn, JN; Collins, PW; Docter, S; Graneto, MJ; Gregory, SA; Isakson, PC; Koboldt, CM; Lee, LF; Malecha, JW; Miyashiro, JM; Penning, TD; Perkins, WE; Rogers, RS; Rogier, DJ; Seibert, K; Talley, JJ; Veenhuizen, AW; Yu, SS; Zhang, YY | 1 |
| Casini, A; Heine, A; Klebe, G; Kuhn, D; Scozzafava, A; Supuran, CT; Weber, A | 1 |
| Bilter, GK; Dias, J; Huang, Z; Keon, BH; Lamerdin, J; MacDonald, ML; Michnick, SW; Minami, T; Owens, S; Shang, Z; Westwick, JK; Yu, H | 1 |
| Abraham, WM; Albert, L; Behnke, ML; Chen, L; Clark, JD; Donahue, F; Foley, MA; Goodwin, DG; Hegen, M; Hu, B; Hu, Y; Ipek, M; Keith, J; Kirincich, SJ; Ku, MS; Lee, KL; McKew, JC; Michalak, R; Murphy, EA; Nickerson-Nutter, CL; Ramarao, MK; Shen, MW; Sum, FW; Tam, S; Thakker, P; Thomason, J; Williams, C; Wooder, L; Wu, K; Xu, X | 1 |
| Chen, L; Clark, JD; Goodwin, DG; Lee, KL; McKew, JC; Murphy, EA; Nickerson-Nutter, C; Shen, MW; Tam, S; Wang, W; Xu, X; Zhang, W | 1 |
| Blobaum, AL; Crews, BC; Daniel, CM; Ghebreselasie, K; Kingsley, PJ; Liedtke, AJ; Marnett, LJ | 1 |
| Buscató, E; Deckmann, K; Geisslinger, G; Grösch, S; Proschak, E; Rörsch, F; Schneider, G; Schubert-Zsilavecz, M | 1 |
| Amini, M; Amirhamzeh, A; Assadieskandar, A; Ostad, SN; Ozadali, K; Salehi, M; Shafiee, A | 1 |
| Ferreiros, N; Geisslinger, G; Grösch, S; Hanke, T; Proschak, E; Rörsch, F; Schneider, G; Schubert-Zsilavecz, M; Thieme, TM | 1 |
| Lavecchia, A; Malerba, P; Perrone, MG; Scilimati, A; Vitale, P | 1 |
| Alfonso, S; Anzini, M; Biava, M; Consalvi, S; Di Capua, A; Di Cesare Mannelli, L; Ghelardini, C; La Motta, C; Pirolli, A; Poce, G; Ragno, R; Sabatino, M; Sartini, S | 1 |
| Chaturbhuj, GU; Goyal, SN; Indalkar, KS; Khatri, CK; Patil, CR | 1 |
| Chung, HY; Hong, J; Ju, Z; Jung, JH; Kim, S; La Kim, E; Moon, HR; Su, M | 1 |
| Bhardwaj, A; Kaur, J; Wuest, F | 1 |
| Isakson, PC; Koboldt, CM; Masferrer, JL; Muhammad, J; Seibert, K; Shaffer, A; Smith, CJ; Talley, JJ; Zhang, Y; Zweifel, BS | 1 |
| McKnight, W; Reuter, BK; Vergnolle, N; Wallace, JL | 1 |
| Gierse, JK; Isakson, PC; Kiefer, JR; Koboldt, CM; Kurumbail, RG; Moreland, KT; Seibert, K; Walker, MC | 1 |
| Bräutigam, L; Geisslinger, G; Grösch, S; Niederberger, E; Tegeder, I | 1 |
| Bräutigam, L; Geisslinger, G; Niederberger, E; Tegeder, I; Vetter, G | 1 |
| Altuna, R; Arroyo, V; Clària, J; Jiménez, W; Koki, AT; López-Parra, M; Masferrer, JL; Planagumà, A; Rivera, F; Rodés, J; Titos, E; Woerner, BM | 1 |
| Nozaki-Taguchi, N; Yamamoto, T | 1 |
| Chen, N; Reiss, CS; Restivo, A | 1 |
| Dunn, AJ; Swiergiel, AH | 1 |
| Carter, J; Gierse, J; Hood, B; Isakson, P; Kiefer, J; Koboldt, C; Kurumbail, R; Marnett, L; Monahan, J; Moreland, K; Pawlitz, J; Pierce, J; Rowlinson, S; Seibert, K; Stegeman, R; Stevens, A; Talley, J; Walker, M | 1 |
| Akunda, JK; Langenbach, R; Lao, HC; Lee, CA; Sessoms, AR; Slade, RM | 1 |
| Cartwright, C; Chan, D; Felix, E; Fischer, SM; Klein, RD; Madden, T; Menter, DG; Newman, RA; Yang, P | 1 |
| Fiorucci, S; Hollenberg, MD; von der Weid, PY; Wallace, JL | 1 |
| Amrite, AC; Ayalasomayajula, SP; Kompella, UB | 1 |
| Doi, Y; Ito, S; Minami, T; Muratani, T; Nishimura, W; Nishizawa, M | 1 |
| Adami, M; Coppelli, G; Coruzzi, G; Giovannini, E; Guaita, E; Menozzi, A; Pozzoli, C | 1 |
| Bishop-Bailey, D; Mitchell, JA; Vojnovic, I; Warner, TD | 1 |
| Arthur, HM; Borthwick, GM; Burn, J; Johnson, AS; Partington, M; Wilson, R | 1 |
| Bertini, S; Bonardi, S; Coruzzi, G; Giovannini, E; Grandi, D; Menozzi, A; Pozzoli, C; Solenghi, E; Vasina, V | 1 |
| Aoi, Y; Hayashi, S; Kato, S; Nishio, H; Okayama, M; Takeuchi, K | 1 |
| Lee, IO; Seo, Y | 1 |
| Bertini, S; Dacasto, M; Giantin, M; Gobbetti, T; Lopparelli, RM; Menozzi, A; Passeri, B; Poli, E; Pozzoli, C; Zullian, C | 1 |
| Cara, DC; Francischi, JN; Klein, A; Menezes, GB; Pereira-Silva, PE; Rezende, RM | 1 |
| Bingaman, DP; Clark, ML; Penn, JS; Yang, R; Yanni, SE | 1 |
| Bjarnason, IT; Hotz-Behofsits, C; Simpson, RJ; Walley, M | 1 |
| Bradbury, JA; Carey, MA; Germolec, DR; Graves, JP; Rebolloso, YD; Zeldin, DC | 1 |
| Jiang, HR; Li, W; Liu, ML; Wang, J; Xu, XL; Zhai, LY; Zhang, J | 1 |
| Brzozowski, T; Konturek, SJ; Kwiecien, S; Mazurkiewicz-Janik, M; Pajdo, R; Pawlik, M; Pawlik, WW; Ptak-Belowska, A; Sliwowski, Z | 1 |
| Calvello, R; Carbone, ML; Cianciulli, A; Malerba, P; Panaro, MA; Perrone, MG; Scilimati, A; Vitale, P | 1 |
| Cai, JH; Li, W; Tang, YX; Wan, L; Zhang, J | 1 |
| Akiba, Y; Amagase, K; Ebara, S; Satoh, H; Takeuchi, K | 1 |
| Cai, J; Li, W; Liu, M; Tang, Y; Zhai, L; Zhang, J | 1 |
| Cai, KQ; Smedberg, J; Smith, ER; Xu, XX; Yang, WL; Yeasky, T | 1 |
| Kanamoto, R; Kaneko, K; Lazarus, M; Miyazaki, Y; Mizushige, T; Ohinata, K; Urade, Y; Yoshikawa, M | 1 |
| Li, C; Raikwar, NS; Santillan, DA; Santillan, MK; Thomas, CP | 1 |
| Adamski, J; Brzozowski, T; Kwiecien, S; Magierowska, K; Magierowski, M; Mazur-Bialy, AI; Pajdo, R; Sliwowski, Z; Surmiak, M | 1 |
| Chang, CC; Chuang, CL; Hsieh, HG; Huang, HC; Lee, FY; Lee, SD; Lee, WS | 1 |
Other Studies
51 other study(ies) available for celecoxib and sc 560
| Article | Year |
|---|---|
Synthesis and biological evaluation of the 1,5-diarylpyrazole class of cyclooxygenase-2 inhibitors: identification of 4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benze nesulfonamide (SC-58635, celecoxib).
Topics: Animals; Arthritis, Experimental; Arthritis, Rheumatoid; Carrageenan; Celecoxib; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Hyperalgesia; Isoenzymes; Magnetic Resonance Spectroscopy; Male; Membrane Proteins; Molecular Structure; Osteoarthritis; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Rats; Rats, Inbred Lew; Rats, Sprague-Dawley; Structure-Activity Relationship; Sulfonamides | 1997 |
Unexpected nanomolar inhibition of carbonic anhydrase by COX-2-selective celecoxib: new pharmacological opportunities due to related binding site recognition.
Topics: Animals; Binding Sites; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Celecoxib; Crystallography, X-Ray; Cyclooxygenase 2; Intraocular Pressure; Isoenzymes; Isoxazoles; Kinetics; Lactones; Models, Molecular; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Rabbits; Structure-Activity Relationship; Sulfonamides; Sulfones | 2004 |
Identifying off-target effects and hidden phenotypes of drugs in human cells.
Topics: Bacterial Proteins; Cell Line; Cell Proliferation; Cluster Analysis; Drug Design; Drug Evaluation, Preclinical; Genetics; Humans; Luminescent Proteins; Molecular Structure; Phenotype; Recombinant Fusion Proteins; Signal Transduction; Structure-Activity Relationship | 2006 |
Indole cytosolic phospholipase A2 alpha inhibitors: discovery and in vitro and in vivo characterization of 4-{3-[5-chloro-2-(2-{[(3,4-dichlorobenzyl)sulfonyl]amino}ethyl)-1-(diphenylmethyl)-1H-indol-3-yl]propyl}benzoic acid, efipladib.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Benzoates; Biological Availability; Bronchoconstriction; Calorimetry; Carrageenan; Cell Line; Cyclooxygenase 2 Inhibitors; Edema; Group IV Phospholipases A2; Humans; In Vitro Techniques; Isoenzymes; Male; Mice; Protein Binding; Rats; Rats, Sprague-Dawley; Sheep; Structure-Activity Relationship; Sulfonamides | 2008 |
Reactions of functionalized sulfonamides: application to lowering the lipophilicity of cytosolic phospholipase A2alpha inhibitors.
Topics: Animals; Enzyme Inhibitors; Group IV Phospholipases A2; Hydrophobic and Hydrophilic Interactions; Rats; Structure-Activity Relationship; Sulfides; Sulfonamides | 2009 |
Cyclooxygenase-1-selective inhibitors based on the (E)-2'-des-methyl-sulindac sulfide scaffold.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Cyclooxygenase 1; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Drug Screening Assays, Antitumor; Female; Humans; Hydrophobic and Hydrophilic Interactions; Mice; Sheep; Stereoisomerism; Structure-Activity Relationship; Sulindac | 2012 |
Structure-activity relationship of nonacidic quinazolinone inhibitors of human microsomal prostaglandin synthase 1 (mPGES 1).
Topics: Animals; Biological Availability; Cell Line, Tumor; Cell Survival; Enzyme Inhibitors; HeLa Cells; Humans; Intramolecular Oxidoreductases; Mice; Microsomes; Prostaglandin-E Synthases; Quinazolinones; Structure-Activity Relationship | 2012 |
Synthesis, cyclooxygenase inhibitory effects, and molecular modeling study of 4-aryl-5-(4-(methylsulfonyl)phenyl)-2-alkylthio and -2-alkylsulfonyl-1H-imidazole derivatives.
Topics: Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Humans; Imidazoles; Models, Molecular; Structure-Activity Relationship | 2013 |
Synthesis and pharmacological characterization of benzenesulfonamides as dual species inhibitors of human and murine mPGES-1.
Topics: Animals; Benzenesulfonamides; Cell Survival; Dose-Response Relationship, Drug; Enzyme Inhibitors; HeLa Cells; Humans; Intramolecular Oxidoreductases; Ligands; Mice; Molecular Structure; NIH 3T3 Cells; Prostaglandin-E Synthases; Structure-Activity Relationship; Sulfonamides | 2013 |
Selective COX-1 inhibition as a target of theranostic novel diarylisoxazoles.
Topics: Cell Line, Tumor; Cyclooxygenase 1; Cyclooxygenase Inhibitors; Drug Design; Gas Chromatography-Mass Spectrometry; Humans; Inhibitory Concentration 50; Isoxazoles; Magnetic Resonance Spectroscopy; Molecular Docking Simulation; Spectroscopy, Fourier Transform Infrared; Structure-Activity Relationship | 2014 |
Synthesis, biological evaluation and docking analysis of a new series of methylsulfonyl and sulfamoyl acetamides and ethyl acetates as potent COX-2 inhibitors.
Topics: Acetamides; Acetates; Analgesics; Animals; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Drug Design; Humans; Methylation; Mice; Molecular Docking Simulation; Rats, Sprague-Dawley; Rats, Wistar; Structure-Activity Relationship; Sulfur Compounds | 2015 |
Novel 2-phenyl-4,5,6,7-tetrahydro[b]benzothiophene analogues as selective COX-2 inhibitors: Design, synthesis, anti-inflammatory evaluation, and molecular docking studies.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Cyclooxygenase 2 Inhibitors; Drug Design; Edema; Mice; Molecular Docking Simulation; Rats; RAW 264.7 Cells; Thiophenes | 2017 |
Design of balanced COX inhibitors based on anti-inflammatory and/or COX-2 inhibitory ascidian metabolites.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Survival; Cells, Cultured; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Dose-Response Relationship, Drug; Drug Design; Humans; Mice; Models, Molecular; Molecular Structure; RAW 264.7 Cells; Sheep; Structure-Activity Relationship; Urochordata | 2019 |
Development of Fluorescence Imaging Probes for Labeling COX-1 in Live Ovarian Cancer Cells.
Topics: | 2021 |
Pharmacological analysis of cyclooxygenase-1 in inflammation.
Topics: Animals; Arthritis, Experimental; Blood Platelets; Carrageenan; Celecoxib; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Edema; Hyperalgesia; Indomethacin; Inflammation; Isoenzymes; Male; Membrane Proteins; Models, Biological; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Sulfonamides; Thromboxane B2 | 1998 |
NSAID-induced gastric damage in rats: requirement for inhibition of both cyclooxygenase 1 and 2.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Cell Adhesion; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Gastric Mucosa; Isoenzymes; Ketorolac; Leukocytes; Male; Membrane Proteins; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Pyrazoles; Rats; Rats, Wistar; Regional Blood Flow; Stomach; Sulfonamides; Thiophenes | 2000 |
A three-step kinetic mechanism for selective inhibition of cyclo-oxygenase-2 by diarylheterocyclic inhibitors.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Binding, Competitive; Celecoxib; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Isoenzymes; Isoxazoles; Kinetics; Meloxicam; Mice; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Sheep; Sulfonamides; Thiazines; Thiazoles | 2001 |
COX-2 independent induction of cell cycle arrest and apoptosis in colon cancer cells by the selective COX-2 inhibitor celecoxib.
Topics: Animals; Apoptosis; Blotting, Western; Caco-2 Cells; Celecoxib; Cell Cycle; Cell Cycle Proteins; Cell Division; Cell Survival; Colonic Neoplasms; Cyclin-Dependent Kinase Inhibitor p21; Cyclin-Dependent Kinase Inhibitor p27; Cyclins; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; HT29 Cells; Humans; Isoenzymes; Membrane Proteins; Mice; Mice, Nude; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Sulfonamides; Tumor Cells, Cultured; Tumor Suppressor Proteins; Xenograft Model Antitumor Assays | 2001 |
Effects of selective COX-1 and -2 inhibition on formalin-evoked nociceptive behaviour and prostaglandin E(2) release in the spinal cord.
Topics: Animals; Behavior, Animal; Celecoxib; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Formaldehyde; Isoenzymes; Membrane Proteins; Microdialysis; Pain; Pain Measurement; Posterior Horn Cells; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Rats; Rats, Sprague-Dawley; RNA, Messenger; Spinal Cord; Sulfonamides | 2001 |
Cyclooxygenase-1 derived prostaglandins are involved in the maintenance of renal function in rats with cirrhosis and ascites.
Topics: Animals; Ascites; Blotting, Western; Carbon Tetrachloride Poisoning; Celecoxib; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Diuretics; Furosemide; Immunohistochemistry; Isoenzymes; Kidney; Liver Cirrhosis, Experimental; Male; Membrane Proteins; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Pyrazoles; Rats; Rats, Wistar; Sulfonamides; Water | 2002 |
The role of cyclooxygenase-1 and -2 in the rat formalin test.
Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Formaldehyde; Indomethacin; Injections, Spinal; Isoenzymes; Male; Membrane Proteins; Neural Conduction; Pain; Pain Measurement; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Rats; Rats, Sprague-Dawley; Sulfonamides | 2002 |
Selective inhibition of COX-2 is beneficial to mice infected intranasally with VSV.
Topics: Animals; Arachidonate 5-Lipoxygenase; Blotting, Western; Celecoxib; Central Nervous System; Cyclooxygenase 1; Cyclooxygenase 2; Interferon-gamma; Interleukin-12; Isoenzymes; Membrane Proteins; Mice; Neutrophils; Nitric Oxide Synthase; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Reverse Transcriptase Polymerase Chain Reaction; Rhabdoviridae Infections; Sulfonamides; Time Factors; Vesicular stomatitis Indiana virus | 2002 |
Distinct roles for cyclooxygenases 1 and 2 in interleukin-1-induced behavioral changes.
Topics: Animals; Behavior, Animal; Body Weight; Celecoxib; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Eating; Interleukin-1; Isoenzymes; Lipopolysaccharides; Male; Membrane Proteins; Mice; Mice, Knockout; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Sulfonamides | 2002 |
Mechanism of inhibition of novel COX-2 inhibitors.
Topics: Celecoxib; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Humans; Isoenzymes; Isoxazoles; Kinetics; Membrane Proteins; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Recombinant Proteins; Sulfonamides; Time Factors | 2002 |
Genetic deficiency or pharmacological inhibition of cyclooxygenase-1 or -2 induces mouse keratinocyte differentiation in vitro and in vivo.
Topics: Animals; Antineoplastic Agents; Apoptosis; Celecoxib; Cell Differentiation; Cells, Cultured; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Epidermal Cells; Isoenzymes; Keratinocytes; Keratins; Membrane Proteins; Mice; Mice, Knockout; Prostaglandin-Endoperoxide Synthases; Protein Precursors; Pyrazoles; Skin Neoplasms; Sulfonamides | 2004 |
Formation and antiproliferative effect of prostaglandin E(3) from eicosapentaenoic acid in human lung cancer cells.
Topics: Alprostadil; Celecoxib; Cell Death; Cell Line, Tumor; Cell Proliferation; Cyclooxygenase 2; DNA; Eicosapentaenoic Acid; Humans; Lung Neoplasms; Membrane Proteins; Microscopy, Fluorescence; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Sulfonamides | 2004 |
Aspirin-triggered, cyclooxygenase-2-dependent lipoxin synthesis modulates vascular tone.
Topics: Acetylcholine; Animals; Aorta; Aspirin; Blood Pressure; Celecoxib; Cyclooxygenase 2 Inhibitors; Endothelium, Vascular; Hydroxyurea; Lipoxins; Lipoxygenase Inhibitors; Male; Mesenteric Arteries; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitroarginine; Oligopeptides; Pyrazoles; Rats; Rats, Sprague-Dawley; Rats, Wistar; Receptors, Lipoxin; Sulfonamides; Vascular Resistance; Vasodilation; Vasodilator Agents | 2004 |
Inhibition of cyclooxygenase-2, but not cyclooxygenase-1, reduces prostaglandin E2 secretion from diabetic rat retinas.
Topics: Animals; Celecoxib; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Dinoprostone; In Vitro Techniques; Membrane Proteins; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Rats; Rats, Sprague-Dawley; Retina; Sulfonamides; Time Factors | 2004 |
Preemptive analgesia by zaltoprofen that inhibits bradykinin action and cyclooxygenase in a post-operative pain model.
Topics: Administration, Oral; Analgesia; Animals; Anti-Inflammatory Agents, Non-Steroidal; Benzopyrans; Bradykinin; Celecoxib; Cyclooxygenase Inhibitors; Injections, Spinal; Male; Mice; Pain, Postoperative; Propionates; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Receptor, Bradykinin B2; RNA, Messenger; Sulfonamides | 2005 |
Effects of cyclooxygenase-1 and -2 inhibition on gastric acid secretion and cardiovascular functions in rats.
Topics: Animals; Blood Pressure; Celecoxib; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Gastric Acid; Heart Rate; Hemodynamics; Indomethacin; Male; Pentagastrin; Pyrazoles; Rats; Rats, Wistar; Sulfonamides; Vagotomy | 2006 |
Influence of plasma protein on the potencies of inhibitors of cyclooxygenase-1 and -2.
Topics: Aspirin; Blood Platelets; Blood Proteins; Calcimycin; Calcium; Celecoxib; Cell Line; Cerebrospinal Fluid Proteins; Cyclooxygenase 1; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Diclofenac; Dinoprostone; Humans; Indomethacin; Ionophores; Lactones; Meloxicam; Naproxen; Organ Specificity; Organic Chemicals; Protein Binding; Pyrazoles; Sodium Salicylate; Sulfonamides; Sulfones; Synovial Fluid; Thiazines; Thiazoles; Thromboxane A2 | 2006 |
Therapeutic levels of aspirin and salicylate directly inhibit a model of angiogenesis through a Cox-independent mechanism.
Topics: Antineoplastic Agents; Aspirin; Celecoxib; Cell Line; Cell Proliferation; Cell Survival; Cyclooxygenase Inhibitors; Endothelial Cells; Humans; Neovascularization, Physiologic; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Salicylic Acid; Sulfonamides | 2006 |
Intestinal effects of nonselective and selective cyclooxygenase inhibitors in the rat.
Topics: Administration, Oral; Analysis of Variance; Animals; Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Enterobacteriaceae; Ibuprofen; Indomethacin; Intestinal Mucosa; Intestine, Small; Lipid Peroxidation; Male; Mucins; Peroxidase; Pyrazoles; Rats; Rats, Wistar; Sulfonamides | 2006 |
Aggravation by selective COX-1 and COX-2 inhibitors of dextran sulfate sodium (DSS)-induced colon lesions in rats.
Topics: Animals; Cardiovascular Diseases; Celecoxib; Colitis, Ulcerative; Colon; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Dextran Sulfate; Dinoprostone; Disease Models, Animal; Gene Expression; Indomethacin; Male; Peroxidase; Plasma Substitutes; Pyrazoles; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Spectrophotometry; Sulfonamides; Treatment Outcome | 2007 |
The effects of intrathecal cyclooxygenase-1, cyclooxygenase-2, or nonselective inhibitors on pain behavior and spinal Fos-like immunoreactivity.
Topics: Animals; Behavior, Animal; Celecoxib; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Formaldehyde; Hyperalgesia; Immunohistochemistry; Injections, Spinal; Ketorolac; Male; Membrane Proteins; Pain; Pain Measurement; Posterior Horn Cells; Proto-Oncogene Proteins c-fos; Pyrazoles; Rats; Rats, Sprague-Dawley; Sulfonamides; Time Factors | 2008 |
Effects of nonselective and selective cyclooxygenase inhibitors on small intestinal motility in the horse.
Topics: Animals; Celecoxib; Clonixin; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Gastrointestinal Motility; Histocytochemistry; Horses; In Vitro Techniques; Indomethacin; Intestine, Small; Male; Pyrazoles; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sulfonamides | 2009 |
Differential involvement of cyclooxygenase isoforms in neutrophil migration in vivo and in vitro.
Topics: Animals; Celecoxib; Cell Adhesion; Cell Movement; Cell Separation; Chemotaxis, Leukocyte; Cyclooxygenase 1; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Data Interpretation, Statistical; Endothelium, Vascular; Female; Indomethacin; Isoenzymes; Male; Mice; Neutrophil Infiltration; Neutrophils; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Rats; Rats, Sprague-Dawley; Sulfonamides | 2008 |
The effects of nepafenac and amfenac on retinal angiogenesis.
Topics: Analysis of Variance; Animals; Animals, Newborn; Anti-Inflammatory Agents, Non-Steroidal; Benzeneacetamides; Celecoxib; Cell Proliferation; Cyclooxygenase Inhibitors; Dinoprostone; Disease Models, Animal; Dose-Response Relationship, Drug; Epithelial Cells; Gene Expression Regulation; Humans; Neuroglia; Oxygen; Phenylacetates; Prostaglandins; Pyrazoles; Rats; Rats, Long-Evans; Rats, Sprague-Dawley; Retina; Retinal Neovascularization; Retinal Vessels; Sulfonamides; Vascular Endothelial Growth Factor A | 2010 |
Role of COX-2 in nonsteroidal anti-inflammatory drug enteropathy in rodents.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Cyclooxygenase 2; Dinoprostone; Flurbiprofen; Inflammation; Intestine, Small; Male; Mice; Pyrazoles; Rats; Rats, Sprague-Dawley; Sulfonamides | 2010 |
Pharmacologic inhibition of COX-1 and COX-2 in influenza A viral infection in mice.
Topics: Animals; Celecoxib; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Female; Influenza A virus; Mice; Orthomyxoviridae Infections; Pyrazoles; Sulfonamides | 2010 |
Combined effects of cyclooxygenase-1 and cyclooxygenase-2 selective inhibitors on ovarian carcinoma in vivo.
Topics: Animals; Celecoxib; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Female; Humans; Mice; Ovarian Neoplasms; Pyrazoles; Sulfonamides; Xenograft Model Antitumor Assays | 2011 |
Nitric oxide (NO)-releasing aspirin exhibits a potent esophagoprotection in experimental model of acute reflux esophagitis. Role of nitric oxide and proinflammatory cytokines.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Celecoxib; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Cytokines; Dinoprostone; Esophagitis, Peptic; Esophagus; Gastric Acid; Humans; Indomethacin; Male; Nitric Oxide; Nitric Oxide Donors; Nitroglycerin; Pyrazoles; Rats; Rats, Wistar; RNA, Messenger; Sulfonamides | 2011 |
Novel selective COX-1 inhibitors suppress neuroinflammatory mediators in LPS-stimulated N13 microglial cells.
Topics: Animals; Aspirin; Celecoxib; Cell Line; Cell Survival; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Dose-Response Relationship, Drug; Down-Regulation; Etoricoxib; I-kappa B Proteins; Inflammation Mediators; Intramolecular Oxidoreductases; Lipopolysaccharides; Membrane Proteins; Mice; Microglia; NF-kappa B; NF-KappaB Inhibitor alpha; Nitric Oxide; Nitric Oxide Synthase Type II; Phosphorylation; Prostaglandin-E Synthases; Pyrazoles; Pyridines; RNA, Messenger; Sulfonamides; Sulfones | 2012 |
Effects of cyclooxygenase inhibitors in combination with taxol on expression of cyclin D1 and Ki-67 in a xenograft model of ovarian carcinoma.
Topics: Animals; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Celecoxib; Cell Proliferation; Cyclin D1; Cyclooxygenase Inhibitors; Female; Humans; Immunoenzyme Techniques; Ki-67 Antigen; Mice; Mice, Nude; Ovarian Neoplasms; Paclitaxel; Pyrazoles; Sulfonamides; Tumor Cells, Cultured; Xenograft Model Antitumor Assays | 2012 |
Cyclooxygenase (COX)-1 and COX-2 both play an important role in the protection of the duodenal mucosa in cats.
Topics: Animals; Blotting, Western; Cats; Celecoxib; Cimetidine; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Diet; Dinoprostone; Duodenal Diseases; Duodenum; Female; Histamine H2 Antagonists; Immunohistochemistry; Intestinal Mucosa; Male; Pyrazoles; Sulfonamides | 2013 |
Antitumor properties of taxol in combination with cyclooxygenase-1 and cyclooxygenase-2 selective inhibitors on ovarian tumor growth in vivo.
Topics: Animals; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Celecoxib; Cell Proliferation; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Female; Humans; Immunoenzyme Techniques; In Situ Nick-End Labeling; Mice; Mice, Nude; Ovarian Neoplasms; Paclitaxel; Pyrazoles; Sulfonamides; Tumor Cells, Cultured | 2012 |
Cyclooxygenase-1 inhibition prolongs postnatal ovarian follicle lifespan in mice.
Topics: Aging; Animals; Celecoxib; Crosses, Genetic; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Female; Indomethacin; Membrane Proteins; Menopause; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Mutant Strains; Ovarian Follicle; Primary Ovarian Insufficiency; Pyrazoles; Random Allocation; Sexual Development; Sulfonamides | 2013 |
δ-Opioid receptor activation stimulates normal diet intake but conversely suppresses high-fat diet intake in mice.
Topics: Analgesics, Opioid; Animals; Celecoxib; Cyclooxygenase Inhibitors; Diet, High-Fat; Eating; Enkephalin, D-Penicillamine (2,5)-; Male; Mice; Pyrazoles; Receptors, Opioid, delta; Receptors, Prostaglandin; Sulfonamides | 2014 |
Aspirin inhibits expression of sFLT1 from human cytotrophoblasts induced by hypoxia, via cyclo-oxygenase 1.
Topics: Adult; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Celecoxib; Cell Hypoxia; Cell Line; Cells, Cultured; Chlorocebus aethiops; COS Cells; Cyclooxygenase 1; Cyclooxygenase Inhibitors; Female; Gene Expression Regulation, Developmental; Humans; Pre-Eclampsia; Pregnancy; Pyrazoles; Recombinant Proteins; Solubility; Trophoblasts; Vascular Endothelial Growth Factor Receptor-1 | 2015 |
The Protective Role of Carbon Monoxide (CO) Produced by Heme Oxygenases and Derived from the CO-Releasing Molecule CORM-2 in the Pathogenesis of Stress-Induced Gastric Lesions: Evidence for Non-Involvement of Nitric Oxide (NO).
Topics: Animals; Carbon Monoxide; Celecoxib; Cyclooxygenase 2; Gastric Mucosa; Heme Oxygenase (Decyclizing); Hemin; Hypoxia-Inducible Factor 1, alpha Subunit; Indomethacin; Male; Nitric Oxide; Nitric Oxide Synthase Type II; Nitroarginine; Organometallic Compounds; Protoporphyrins; Pyrazoles; Rats; Rats, Wistar; RNA, Messenger; Stress, Physiological | 2016 |
Selective cyclooxygenase inhibition by SC-560 improves hepatopulmonary syndrome in cirrhotic rats.
Topics: Animals; Celecoxib; Cyclooxygenase 1; Cyclooxygenase Inhibitors; Disease Models, Animal; Down-Regulation; Hemodynamics; Hepatopulmonary Syndrome; Liver; Liver Cirrhosis; Lung; Male; NF-kappa B; Pyrazoles; Rats; Rats, Sprague-Dawley; Tumor Necrosis Factor-alpha; Vascular Endothelial Growth Factor A | 2017 |