Compounds > celecoxib

celecoxib and phenytoin

celecoxib has been researched along with phenytoin in 13 studies

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (15.38)18.2507
2000's6 (46.15)29.6817
2010's5 (38.46)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Ekins, S; Williams, AJ; Xu, JJ1
Honda, K; Izumi, T; Miyaji, Y; Nakayama, S; Okazaki, O; Okudaira, N; Shiosakai, K; Sugiyama, D; Suzuki, W; Takakusa, H; Watanabe, A1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Nightingale, SL1
Rodrigues, AD; Shou, M; Tang, C1
Malhotra, S; Pandhi, P; Shafiq, N1
Batchelor, T; Desideri, S; Grossman, SA; Hammour, T; Lesser, G; Olson, J; Peereboom, D; Supko, JG; Ye, X1

Reviews

1 review(s) available for celecoxib and phenytoin

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Trials

1 trial(s) available for celecoxib and phenytoin

ArticleYear
Effect of phenytoin on celecoxib pharmacokinetics in patients with glioblastoma.
    Neuro-oncology, 2008, Volume: 10, Issue:2

    Topics: Aged; Aged, 80 and over; Anticonvulsants; Antineoplastic Agents; Area Under Curve; Brain Neoplasms; Celecoxib; Combined Modality Therapy; Drug Interactions; Female; Glioblastoma; Humans; Male; Middle Aged; Phenytoin; Pyrazoles; Radiotherapy; Seizures; Sulfonamides

2008

Other Studies

11 other study(ies) available for celecoxib and phenytoin

ArticleYear
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
    Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship

2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Combination of GSH trapping and time-dependent inhibition assays as a predictive method of drugs generating highly reactive metabolites.
    Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:7

    Topics: Glutathione; Pharmacology; Sulfur Radioisotopes

2011
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
    Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10

    Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection

2012
From the Food and Drug Administration.
    JAMA, 1999, Mar-03, Volume: 281, Issue:9

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Anticonvulsants; Arthritis; Celecoxib; Communicable Diseases; Cyclooxygenase Inhibitors; Drug Contamination; Drug Labeling; Humans; Phenytoin; Plasminogen Activators; Prodrugs; Pyrazoles; Sulfonamides; United States; United States Food and Drug Administration; Urokinase-Type Plasminogen Activator

1999
Celebrex mix-up.
    Health news (Waltham, Mass.), 1999, Sep-10, Volume: 5, Issue:11

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Anticonvulsants; Antidepressive Agents; Carrier Proteins; Celecoxib; Humans; Medication Errors; Names; Phenytoin; Pyrazoles; Receptors, Drug; Sulfonamides

1999
Substrate-dependent effect of acetonitrile on human liver microsomal cytochrome P450 2C9 (CYP2C9) activity.
    Drug metabolism and disposition: the biological fate of chemicals, 2000, Volume: 28, Issue:5

    Topics: Acetonitriles; Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Blocking; Anticonvulsants; Aryl Hydrocarbon Hydroxylases; Celecoxib; Cytochrome P-450 CYP2C9; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Diclofenac; Enzyme Inhibitors; Humans; Hypoglycemic Agents; In Vitro Techniques; Microsomes, Liver; Phenotype; Phenytoin; Pyrazoles; Steroid 16-alpha-Hydroxylase; Steroid Hydroxylases; Sulfonamides; Tolbutamide

2000
Cutaneous drug reaction case reports: from the world literature.
    American journal of clinical dermatology, 2002, Volume: 3, Issue:1

    Topics: Adult; Adverse Drug Reaction Reporting Systems; Aged; Bupropion; Celecoxib; Chlorquinaldol; Cytarabine; Dalteparin; Dapsone; Dermatitis, Contact; Drug Hypersensitivity; Felodipine; Female; Humans; Male; Middle Aged; Phenytoin; Pregnancy; Pyrazoles; Scabies; Sulfonamides; Sweet Syndrome; Vancomycin

2002
Anticonvulsant action of celecoxib (alone and in combination with sub-threshold dose of phenytoin) in electroshock induced convulsion.
    Methods and findings in experimental and clinical pharmacology, 2003, Volume: 25, Issue:2

    Topics: Animals; Anticonvulsants; Celecoxib; Cyclooxygenase Inhibitors; Drug Synergism; Drug Therapy, Combination; Electroshock; Male; Phenytoin; Pyrazoles; Rats; Rats, Wistar; Seizures; Sulfonamides

2003