celecoxib has been researched along with nimesulide in 61 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 1 (1.64) | 18.2507 |
2000's | 39 (63.93) | 29.6817 |
2010's | 20 (32.79) | 24.3611 |
2020's | 1 (1.64) | 2.80 |
Authors | Studies |
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Damas, J; de Leval, X; Dogné, JM; Julémont, F; Michaux, C; Montero, JL; Pirotte, B; Renard, JF; Winum, JY | 1 |
Caciagli, B; Carotti, S; Chiricosta, G; Landini, I; Maccari, R; Mini, E; Ottanà, R; Vigorita, MG | 1 |
Arslan, D; de Leval, X; Garbacki, N; Pirotte, B; Renard, JF | 1 |
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
Ekins, S; Williams, AJ; Xu, JJ | 1 |
Chen, SH; Gu, LQ; Huang, ZS; Li, D; Li, Y; Ou, TM; Tan, JH | 1 |
Meanwell, NA | 1 |
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
de Leval, X; Hubert, P; Lecomte, F; Pirotte, B; Renard, JF | 1 |
Singh, P; Tewari, AK; Yadav, P | 1 |
Arai, J; Hisa, T; Maeda, M; Mukai, T; Ohkubo, Y; Ohshima, T; Saito, Y; Yamamoto, F; Yamamoto, Y | 1 |
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
Bernardino, AMR; Boechat, N; Dos Santos, MS; Faria, JV; Miguita, AGC; Vegi, PF | 1 |
Wallace, JL | 1 |
Hawkey, CJ; Jackson, LM | 1 |
Cairns, SR; O'Beirne, JP | 1 |
Mejza, F; Nizankowska, E | 1 |
Friel, AM; Healy, DG; Morrison, JJ; Slattery, MM | 1 |
Kawamori, T; Wakabayashi, K | 1 |
Bianchi, M; Broggini, M | 2 |
Malhotra, S; Pandhi, P; Shafiq, N | 2 |
Devière, J | 1 |
Gazi, MH; Pan, Y; Young, CY; Zhang, JS | 1 |
Bhatia, S; Seedher, N | 1 |
Chen, PY; Long, QC | 1 |
Benoit, V; de Leval, X; Dogné, JM; Frederich, M; Julémont, F; Pirotte, B | 1 |
Meena, S; Nagaraju, D; Rao, AR; Rao, RN | 1 |
Canonica, GW; D'Amato, G; Liccardi, G; Lobefalo, G; Noschese, P; Passalacqua, G; Piccolo, A; Salzillo, A | 1 |
D'Amato, G; D'Amato, M; Liccardi, G; Piccolo, A; Piscitelli, E; Salzillo, A; Senna, G | 1 |
Meena, S; Nageswara Rao, R; Raghuram Rao, A | 1 |
Mullangi, R; Pavan Kumar, VV; Ramani, AV; Srinivas, NR; Vinu, MC | 1 |
Malhotra, S; Nada, R; Pandhi, P; Shafiq, N | 1 |
Arakawa, T; Fujiwara, Y; Hamaguchi, M; Hayakawa, T; Higuchi, K; Okuyama, M; Oshitani, N; Sasaki, E; Sugawa, T; Tominaga, K; Watanabe, T | 1 |
Fraunfelder, FW; Mehelas, TJ; Solomon, J | 1 |
Kandefer-Szerszeń, M; Majdan, M; Parada-Turska, J; Rzeski, W; Turski, WA | 1 |
Arana, A; Castellsague, J; Perez-Gutthann, S; Sanchez-Matienzo, D | 1 |
Bagcivan, I; Cetin, A; Gulturk, S; Gursoy, S; Karadas, B; Kaya, T; Parlak, A | 1 |
Ballmer-Weber, BK; Hofbauer, G; Roll, A; Schmid-Grendelmeier, P; Wüthrich, B | 1 |
Becker, TL; Gambero, A; Maróstica, M; Pedrazzoli, J | 1 |
Nikitakis, NG; Sauk, JJ; Scheper, MA | 1 |
Balzarini, P; Bianchi, M; Broggini, M; Franchi, S; Sacerdote, P | 1 |
Dastis, SN; Geubel, AP; Lerut, J; Rahier, J | 1 |
Buyse, M; Farinotti, R; Zrieki, A | 1 |
Han, JA; Kim, SR; Lee, ME; Park, JH; Park, JS; Park, SC | 1 |
Chan, PC; Chen, CH; Chiang, CF; Hsieh, PS; Jin, JS; Shih, KC | 1 |
King, RS; Struzik, SM; Yalcin, EB | 1 |
Clapper, ML; Foreman, JE; Gonzalez, FJ; McGinnis, KS; Peters, JM; Rigas, B; Sorg, JM; Williams, JL | 1 |
Dolezal, T; Krsiak, M; Sliva, J; Sykora, D; Vosmanska, M | 1 |
Chen, CH; Chiang, CF; Hsieh, PS; Lu, KC | 1 |
Cetin, A; Cetin, M; Guvenal, T; Timuroglu, Y; Yanar, O | 1 |
Chen, CH; Hsia, TL; Hsieh, CH; Hsieh, PS; Huang, DW; Tian, YF | 1 |
Cerella, C; Chateauvieux, S; Dicato, M; Diederich, M; Ghelfi, J; Henry, E; Schnekenburger, M; Sobolewski, C | 1 |
Cerella, C; Dicato, M; Diederich, M; Sobolewski, C | 1 |
Gaur, V; Kumar, A | 1 |
Ahmed, S; Ercisli, S; Gul, H; Gul, S; Zia-Ul-Haq, M | 1 |
Aujla, U; Bjarnason, I; Kvasnovsky, CL | 1 |
Ahmed, S; Gul, S; Riaz, M; Zia-ul-Haq, M | 1 |
Davydkin, IL; Zolotovskaia, IA | 1 |
Çakmak, ME | 1 |
9 review(s) available for celecoxib and nimesulide
Article | Year |
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DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Recently reported biological activities of pyrazole compounds.
Topics: Analgesics; Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Antifungal Agents; Antineoplastic Agents; Antiviral Agents; Humans; Pyrazoles | 2017 |
Distribution and expression of cyclooxygenase (COX) isoenzymes, their physiological roles, and the categorization of nonsteroidal anti-inflammatory drugs (NSAIDs).
Topics: Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Controlled Clinical Trials as Topic; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Etodolac; Gene Expression; Humans; Ibuprofen; Indomethacin; Isoenzymes; Meloxicam; Membrane Proteins; Naproxen; Nitrobenzenes; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Sulfonamides; Thiazines; Thiazoles | 1999 |
COX-2 selective nonsteroidal anti-Inflammatory drugs: do they really offer any advantages?
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Cyclooxygenase Inhibitors; Enzyme Inhibitors; Etodolac; Humans; Lactones; Meloxicam; Pyrazoles; Sulfonamides; Sulfones; Thiazines; Thiazoles | 2000 |
[Selective cyclooxygenase 2 inhibitors (COX-2)].
Topics: Celecoxib; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Humans; Inflammation; Isoenzymes; Lactones; Meloxicam; Membrane Proteins; Prostaglandin-Endoperoxide Synthases; Protein Isoforms; Pyrazoles; Sulfonamides; Sulfones; Thiazines; Thiazoles | 2001 |
Do selective cyclo-oxygenase inhibitors eliminate the adverse events associated with nonsteroidal anti-inflammatory drug therapy?
Topics: Alzheimer Disease; Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Cyclooxygenase Inhibitors; Humans; Lactones; Meloxicam; Neoplasms; Pyrazoles; Sulfonamides; Sulfones; Thiazines; Thiazoles | 2002 |
First and second generations of COX-2 selective inhibitors.
Topics: Celecoxib; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Etoricoxib; Gastrointestinal Diseases; Humans; Isoenzymes; Isoxazoles; Lactones; Membrane Proteins; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Pyridines; Sulfonamides; Sulfones | 2004 |
An overview of the recent developments in analytical methodologies for determination of COX-2 inhibitors in bulk drugs, pharmaceuticals and biological matrices.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Chemistry, Pharmaceutical; Chromatography; Chromatography, High Pressure Liquid; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Drug Industry; Etodolac; Etoricoxib; Lactones; Models, Chemical; Pyrazoles; Pyridines; Spectrophotometry; Sulfonamides; Sulfones; Ultraviolet Rays | 2005 |
Nonsteroidal anti-inflammatory drugs and exacerbations of inflammatory bowel disease.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Clinical Trials as Topic; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Etoricoxib; Gastrointestinal Tract; Humans; Inflammatory Bowel Diseases; Observational Studies as Topic; Pain; Pyrazoles; Pyridines; Recurrence; Sulfonamides; Sulfones | 2015 |
7 trial(s) available for celecoxib and nimesulide
Article | Year |
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Uterine relaxant effects of cyclooxygenase-2 inhibitors in vitro.
Topics: Adult; Celecoxib; Cesarean Section; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Female; Humans; Hysterectomy; Isoenzymes; Labor, Obstetric; Meloxicam; Membrane Proteins; Middle Aged; Myometrium; Pregnancy; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Sulfonamides; Thiazines; Thiazoles; Uterine Contraction | 2001 |
Anti-hyperalgesic effects of nimesulide: studies in rats and humans.
Topics: Aged; Analysis of Variance; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Celecoxib; Diclofenac; Double-Blind Method; Female; Humans; Hyperalgesia; Lactones; Male; Middle Aged; Models, Animal; Pyrazoles; Rats; Rats, Sprague-Dawley; Sulfonamides; Sulfones | 2002 |
A randomised, double-blind, clinical trial comparing the efficacy of nimesulide, celecoxib and rofecoxib in osteoarthritis of the knee.
Topics: Adult; Aged; Analysis of Variance; Celecoxib; Double-Blind Method; Female; Humans; Knee; Lactones; Male; Middle Aged; Osteoarthritis; Osteoarthritis, Knee; Pain; Pain Measurement; Pyrazoles; Sulfonamides; Sulfones; Time Factors | 2003 |
Safety of celecoxib in patients with adverse reactions to nimesulide.
Topics: Adolescent; Adult; Aged; Angioedema; Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Drug Hypersensitivity; Erythema; Female; Humans; Male; Middle Aged; Pyrazoles; Single-Blind Method; Sulfonamides; Urticaria | 2005 |
Safety of celecoxib in patients with adverse skin reactions to acetaminophen (paracetamol) and nimesulide associated or not with common non-steroidal anti-inflammatory drugs.
Topics: Acetaminophen; Adolescent; Adult; Aged; Angioedema; Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Cyclooxygenase Inhibitors; Dose-Response Relationship, Immunologic; Drug Combinations; Drug Eruptions; Drug Hypersensitivity; Female; Humans; Hypersensitivity, Immediate; Male; Middle Aged; Pyrazoles; Single-Blind Method; Skin Tests; Sulfonamides | 2005 |
Tolerance to celecoxib in patients with a history of adverse reactions to nonsteroidal anti-inflammatory drugs.
Topics: Acetaminophen; Adolescent; Adult; Aged; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Celecoxib; Dose-Response Relationship, Drug; Drug Hypersensitivity; Female; Humans; Male; Middle Aged; Prospective Studies; Pyrazoles; Single-Blind Method; Sulfonamides | 2006 |
Effects of nimesulide on pain and on synovial fluid concentrations of substance P, interleukin-6 and interleukin-8 in patients with knee osteoarthritis: comparison with celecoxib.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthralgia; Celecoxib; Double-Blind Method; Female; Humans; Interleukin-6; Interleukin-8; Male; Osteoarthritis, Knee; Pain Measurement; Pyrazoles; Substance P; Sulfonamides; Synovial Fluid; Treatment Outcome | 2007 |
45 other study(ies) available for celecoxib and nimesulide
Article | Year |
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Design, synthesis, and pharmacological evaluation of pyridinic analogues of nimesulide as cyclooxygenase-2 selective inhibitors.
Topics: Crystallography, X-Ray; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Drug Design; Humans; Isoenzymes; Membrane Proteins; Prostaglandin-Endoperoxide Synthases; Pyridines; Structure-Activity Relationship; Sulfonamides | 2004 |
In vitro antiproliferative activity against human colon cancer cell lines of representative 4-thiazolidinones. Part I.
Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Colonic Neoplasms; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Drug Screening Assays, Antitumor; Humans; Inhibitory Concentration 50; Membrane Proteins; Prostaglandin-Endoperoxide Synthases; Structure-Activity Relationship; Thiazolidinediones | 2005 |
Pyridine analogues of nimesulide: design, synthesis, and in vitro and in vivo pharmacological evaluation as promising cyclooxygenase 1 and 2 inhibitors.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Drug Design; Humans; Pleurisy; Pyrazoles; Pyridines; Rats; Sulfonamides | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
Syntheses and characterization of nimesulide derivatives for dual enzyme inhibitors of both cyclooxygenase-1/2 and 5-lipoxygenase.
Topics: Anti-Inflammatory Agents; Arachidonate 5-Lipoxygenase; Benzoates; Binding Sites; Computer Simulation; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Lipoxygenase Inhibitors; Structure-Activity Relationship; Sulfonamides | 2011 |
Synopsis of some recent tactical application of bioisosteres in drug design.
Topics: Cytochrome P-450 Enzyme System; Drug Design | 2011 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
N-(3-Arylaminopyridin-4-yl)alkanesulfonamides as pyridine analogs of nimesulide: cyclooxygenases inhibition, anti-inflammatory studies and insight on metabolism.
Topics: Animals; Anti-Inflammatory Agents; Cyclooxygenase Inhibitors; Magnetic Resonance Spectroscopy; Pyridines; Rats; Sulfonamides | 2014 |
Design, synthesis, docking and anti-inflammatory evaluation of novel series of benzofuran based prodrugs.
Topics: Animals; Anti-Inflammatory Agents; Benzofurans; Crystallography, X-Ray; Drug Design; Models, Molecular; Molecular Docking Simulation; Prodrugs; Rats | 2014 |
Isomeric methoxy analogs of nimesulide for development of brain cyclooxygense-2 (COX-2)-targeted imaging agents: Synthesis, in vitro COX-2-inhibitory potency, and cellular transport properties.
Topics: Brain; Caco-2 Cells; Catalytic Domain; Contrast Media; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Humans; Isomerism; Molecular Conformation; Molecular Dynamics Simulation; Protein Binding; Sulfonamides | 2015 |
Drug Points: Cholestatic hepatitis in association with celecoxib.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Chemical and Drug Induced Liver Injury; Cholestasis, Intrahepatic; Cyclooxygenase Inhibitors; Female; Humans; Middle Aged; Pyrazoles; Sulfonamides | 2001 |
COX-2 and prostanoid receptors: good targets for chemoprevention.
Topics: Animals; Breast Neoplasms; Celecoxib; Cell Transformation, Neoplastic; Chemoprevention; Colonic Neoplasms; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Enzyme Inhibitors; Female; Humans; Isoenzymes; Male; Membrane Proteins; Mice; Mice, Knockout; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Rats; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP1 Subtype; Sulfonamides | 2002 |
Effect of cyclooxygenase inhibitors in postoperative ileus: an experimental study.
Topics: Animals; Celecoxib; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Female; Indomethacin; Intestinal Obstruction; Male; Postoperative Complications; Pyrazoles; Rats; Rats, Sprague-Dawley; Sulfonamides | 2002 |
The cyclooxygenase 2-specific nonsteroidal anti-inflammatory drugs celecoxib and nimesulide inhibit androgen receptor activity via induction of c-Jun in prostate cancer cells.
Topics: Androgen Receptor Antagonists; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Blotting, Western; Celecoxib; Gene Expression; Genes, jun; Humans; Male; Phosphorylation; Prostatic Neoplasms; Pyrazoles; Sulfonamides; Tacrolimus Binding Proteins; Transfection; Tumor Cells, Cultured | 2003 |
Solubility enhancement of Cox-2 inhibitors using various solvent systems.
Topics: Celecoxib; Chemistry, Pharmaceutical; Cyclooxygenase 2; Enzyme Inhibitors; Hydrogen-Ion Concentration; Isoenzymes; Lactones; Meloxicam; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Solubility; Solvents; Sulfonamides; Sulfones; Thiazines; Thiazoles | 2003 |
Comparison of nonselective cyclo-oxygenase (COX) inhibitor and selective COX-2 inhibitors on preimplantation loss, postimplantation loss and duration of gestation: an experimental study.
Topics: Animals; Celecoxib; Cyclooxygenase Inhibitors; Embryonic Development; Female; Gestational Age; Indomethacin; Pregnancy; Pyrazoles; Rats; Rats, Wistar; Sulfonamides | 2004 |
Effects of cyclooxygenase 2 inhibitors on biological traits of nasopharyngeal carcinoma cells.
Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Apoptosis; Carcinoma, Squamous Cell; Celecoxib; Cell Cycle; Cell Line, Tumor; Chick Embryo; Chorion; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; DNA Fragmentation; Humans; Isoenzymes; Membrane Proteins; Nasopharyngeal Neoplasms; Neovascularization, Pathologic; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Sulfonamides | 2004 |
Development and validation of a reversed-phase liquid chromatographic method for separation and simultaneous determination of COX-2 inhibitors in pharmaceuticals and its application to biological fluids.
Topics: Butanones; Celecoxib; Chromatography, Liquid; Cyclooxygenase 2 Inhibitors; Humans; Isoxazoles; Lactones; Nabumetone; Pyrazoles; Reproducibility of Results; Sensitivity and Specificity; Sulfonamides; Sulfones | 2005 |
Simultaneous quantitation of etoricoxib, salicylic acid, valdecoxib, ketoprofen, nimesulide and celecoxib in plasma by high-performance liquid chromatography with UV detection.
Topics: Animals; Celecoxib; Chromatography, High Pressure Liquid; Etoricoxib; Humans; Isoxazoles; Ketoprofen; Male; Pyrazoles; Pyridines; Rats; Rats, Wistar; Reproducibility of Results; Salicylic Acid; Spectrophotometry, Ultraviolet; Sulfonamides; Sulfones | 2006 |
Comparative gastrointestinal toxicity of selective cyclooxygenase (COX-2) inhibitors.
Topics: Animals; Celecoxib; Colitis; Cyclooxygenase Inhibitors; Gastric Mucosa; Gastrointestinal Tract; Indomethacin; Male; Pyrazoles; Rats; Rats, Wistar; Reperfusion Injury; Sulfonamides | 2005 |
Roles of cyclooxygenase 2 and microsomal prostaglandin E synthase 1 in rat acid reflux oesophagitis.
Topics: Animals; Celecoxib; Cell Division; Chronic Disease; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cytosol; Dinoprostone; Epithelial Cells; Esophagitis, Peptic; Esophagus; Immunohistochemistry; Intramolecular Oxidoreductases; Male; Microsomes; Prostaglandin-E Synthases; Pyrazoles; Rats; Rats, Wistar; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP4 Subtype; Sulfonamides | 2006 |
Ocular adverse effects associated with cyclooxygenase-2 inhibitors.
Topics: Adult; Adverse Drug Reaction Reporting Systems; Aged; Aged, 80 and over; Celecoxib; Conjunctivitis; Cyclooxygenase 2 Inhibitors; Etodolac; Humans; Isoxazoles; Lactones; Middle Aged; Pyrazoles; Sulfonamides; Sulfones; Vision Disorders | 2006 |
Effect of glutamate receptor antagonists and antirheumatic drugs on proliferation of synoviocytes in vitro.
Topics: Animals; Antirheumatic Agents; Benzodiazepines; Benzodiazepinones; Celecoxib; Cell Line; Cell Proliferation; Cell Survival; Diclofenac; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Inhibitory Concentration 50; Methotrexate; Naproxen; Pyrazoles; Quinoxalines; Sulfasalazine; Sulfonamides; Synovial Membrane | 2006 |
Hepatic disorders in patients treated with COX-2 selective inhibitors or nonselective NSAIDs: a case/noncase analysis of spontaneous reports.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Benzophenones; Bromobenzenes; Celecoxib; Chemical and Drug Induced Liver Injury; Cyclooxygenase 2 Inhibitors; Humans; Lactones; Odds Ratio; Pyrazoles; Safety; Sulfonamides; Sulfones; Sulindac | 2006 |
Additive interaction of intraperitoneal dexmedetomidine and topical nimesulide, celecoxib, and DFU for antinociception.
Topics: Administration, Topical; Adrenergic alpha-Agonists; Animals; Celecoxib; Cyclooxygenase 2 Inhibitors; Dexmedetomidine; Drug Administration Routes; Drug Synergism; Furans; Injections, Intraperitoneal; Male; Pain; Pain Measurement; Pyrazoles; Rats; Rats, Wistar; Sulfonamides | 2007 |
Effect of different cyclooxygenase inhibitors on gastric adaptive cytoprotection induced by 20% ethanol.
Topics: Animals; Celecoxib; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Cytoprotection; Diclofenac; Dinoprostone; Dose-Response Relationship, Drug; Enzyme Inhibitors; Ethanol; Gastric Acid; Gastric Mucosa; Ibuprofen; Irritants; Male; Meloxicam; Membrane Proteins; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Pyrazoles; Rats; Rats, Wistar; Stomach Ulcer; Sulfonamides; Thiazines; Thiazoles | 2007 |
Survivin is a downstream target and effector of sulindac-sensitive oncogenic Stat3 signalling in head and neck cancer.
Topics: Annexin A5; Antineoplastic Agents; Apoptosis; Carcinoma, Squamous Cell; Celecoxib; Cell Division; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cyclooxygenase 2 Inhibitors; Cysteine Proteinase Inhibitors; Down-Regulation; Enzyme Inhibitors; Humans; Immunohistochemistry; Indomethacin; Inhibitor of Apoptosis Proteins; Microtubule-Associated Proteins; Neoplasm Proteins; Pyrazoles; Signal Transduction; STAT3 Transcription Factor; Sulfonamides; Sulindac; Survivin; Tongue Neoplasms; Tumor Cells, Cultured | 2007 |
Liver transplantation for nonsteroidal anti-inflammatory drug-induced liver failure: nimesulide as the first implicated compound.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Chemical and Drug Induced Liver Injury; Female; Humans; Liver Failure, Acute; Liver Transplantation; Middle Aged; Piroxicam; Pyrazoles; Sulfonamides | 2007 |
Cyclooxygenase inhibitors down regulate P-glycoprotein in human colorectal Caco-2 cell line.
Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Caco-2 Cells; Celecoxib; Colorectal Neoplasms; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Dinoprostone; Down-Regulation; Drug Resistance, Neoplasm; Gene Expression Regulation, Neoplastic; Humans; Indomethacin; Naproxen; Neoplasm Proteins; Pyrazoles; Reproducibility of Results; RNA, Messenger; Sulfonamides; Time Factors | 2008 |
Selective COX-2 inhibitors modulate cellular senescence in human dermal fibroblasts in a catalytic activity-independent manner.
Topics: Aspirin; Caveolin 1; Celecoxib; Cells, Cultured; Cellular Senescence; Cyclin-Dependent Kinase Inhibitor p21; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Fibroblasts; Flurbiprofen; Humans; Ibuprofen; Kinetics; Models, Biological; NF-kappa B; Nitrobenzenes; Pyrazoles; Reactive Oxygen Species; Skin; Skin Aging; Sulfonamides; Tumor Suppressor Protein p53 | 2008 |
COX-2-mediated inflammation in fat is crucial for obesity-linked insulin resistance and fatty liver.
Topics: Adipocytes; Adipogenesis; Adipose Tissue; Animals; Blood Glucose; Body Weight; Celecoxib; Cell Size; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Dinoprost; Disease Models, Animal; Fatty Liver; Insulin; Insulin Resistance; Leptin; Liver; Macrophages; Male; Membrane Proteins; Obesity; Panniculitis; Pyrazoles; Rats; Rats, Sprague-Dawley; Sulfonamides; Time Factors; Triglycerides; Tumor Necrosis Factor-alpha | 2009 |
Allosteric modulation of SULT2A1 by celecoxib and nimesulide: computational analyses.
Topics: Allosteric Regulation; Binding Sites; Celecoxib; Drug Interactions; Estradiol; Humans; Ligands; Protein Binding; Protein Conformation; Pyrazoles; Software; Sulfonamides; Sulfotransferases | 2008 |
Regulation of peroxisome proliferator-activated receptor-beta/delta by the APC/beta-CATENIN pathway and nonsteroidal antiinflammatory drugs.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; beta Catenin; Blotting, Western; Celecoxib; Colonic Neoplasms; Colonic Polyps; Disease Models, Animal; Female; Genes, APC; Humans; Indomethacin; Mice; Mice, Inbred C57BL; Mice, Knockout; Nitrobenzenes; PPAR delta; PPAR-beta; Pyrazoles; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Sulfonamides; Tumor Cells, Cultured | 2009 |
Guaifenesin enhances the analgesic potency of ibuprofen, nimesulide and celecoxib in mice.
Topics: Acetic Acid; Analgesia; Analysis of Variance; Animals; Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Drug Synergism; Expectorants; Guaifenesin; Ibuprofen; Male; Mice; Pain; Pain Measurement; Pyrazoles; Sulfonamides | 2009 |
Suppressive effect of COX2 inhibitor on the progression of adipose inflammation in high-fat-induced obese rats.
Topics: Adiposity; Animals; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Blood Glucose; Blood Pressure; Celecoxib; Chemokine CCL2; Cyclooxygenase 2 Inhibitors; Disease Models, Animal; Fats; Glucose Tolerance Test; Immunohistochemistry; Inflammation; Insulin; Intra-Abdominal Fat; Obesity; Polymerase Chain Reaction; Pyrazoles; Rats; Rats, Sprague-Dawley; Subcutaneous Fat, Abdominal; Sulfonamides; Triglycerides; Tumor Necrosis Factor-alpha | 2010 |
Effects of selective and non-selective cyclooxygenase (COX) inhibitors on postoperative adhesion formation in a rat uterine horn model.
Topics: Animals; Celecoxib; Cyclooxygenase Inhibitors; Female; Indomethacin; Postoperative Complications; Pyrazoles; Rats; Rats, Wistar; Sulfonamides; Tissue Adhesions; Uterus | 2010 |
The importance of cyclooxygenase 2-mediated oxidative stress in obesity-induced muscular insulin resistance in high-fat-fed rats.
Topics: Adipose Tissue; Animals; Biomarkers; Celecoxib; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Diet, Reducing; Dietary Fats; Gene Expression; Glucose Tolerance Test; Glucose Transporter Type 4; Insulin; Insulin Resistance; Male; Muscle, Skeletal; Obesity; Oxidative Stress; Pyrazoles; Rats; Rats, Sprague-Dawley; Sulfonamides | 2011 |
COX-2 inhibitors block chemotherapeutic agent-induced apoptosis prior to commitment in hematopoietic cancer cells.
Topics: Antineoplastic Agents; Apoptosis; Celecoxib; Cell Line, Tumor; Cyclooxygenase 2 Inhibitors; DNA Damage; Dose-Response Relationship, Drug; Hematologic Neoplasms; Humans; K562 Cells; Nitrobenzenes; Pyrazoles; Signal Transduction; Stress, Physiological; Sulfonamides; U937 Cells | 2011 |
Cox-2 inhibitors induce early c-Myc downregulation and lead to expression of differentiation markers in leukemia cells.
Topics: Antigens, Differentiation; Apoptosis; Biomarkers; Celecoxib; Cell Differentiation; Cell Proliferation; Cell Survival; Cyclin D1; Cyclin-Dependent Kinase Inhibitor p27; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Dinoprostone; Down-Regulation; Gene Expression Regulation, Leukemic; Humans; Interphase; Jurkat Cells; K562 Cells; Nitrobenzenes; p38 Mitogen-Activated Protein Kinases; Proliferating Cell Nuclear Antigen; Proto-Oncogene Proteins c-myc; Pyrazoles; Sulfonamides; U937 Cells; Up-Regulation | 2011 |
Effect of nonselective and selective COX-2 inhibitors on memory dysfunction, glutathione system, and tumor necrosis factor alpha level against cerebral ischemia reperfusion injury.
Topics: Acetylcholinesterase; Animals; Behavior, Animal; Celecoxib; Cyclooxygenase 2 Inhibitors; Glutathione; Hippocampus; Ibuprofen; Male; Maze Learning; Memory Disorders; Pyrazoles; Rats; Rats, Wistar; Reperfusion Injury; Sulfonamides; Tumor Necrosis Factor-alpha | 2012 |
Cyclooxygenase-2 inhibition improves antioxidative defense during experimental hypercholesterolemia.
Topics: Animals; Antioxidants; Celecoxib; Cholesterol, LDL; Cyclooxygenase 2 Inhibitors; Disease Models, Animal; Glutathione Peroxidase; Hypercholesterolemia; Male; Oxidative Stress; Pyrazoles; Rabbits; Sulfonamides; Superoxide Dismutase | 2014 |
Hypolipidemic effects of nimesulide and celecoxib in experimentally induced hypercholesterolemia in rabbits.
Topics: Animals; Celecoxib; Cyclooxygenase Inhibitors; Diet, Atherogenic; Diet, High-Fat; Hypercholesterolemia; Lipoproteins, HDL; Lipoproteins, LDL; Male; Pyrazoles; Rabbits; Sulfonamides; Treatment Outcome; Triglycerides | 2015 |
[Cognitive-cytokine effect of nonsteroidal antiinflammatory drugs in the therapy of elderly patients with osteoarthritis].
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Cognition; Cognition Disorders; Cytokines; Etoricoxib; Female; Humans; Interleukin-1beta; Interleukin-6; Male; Meloxicam; Osteoarthritis; Prospective Studies; Pyridines; Sulfonamides; Sulfones; Thiazines; Thiazoles; Transforming Growth Factor beta1 | 2017 |
Which non-steroidal anti-inflammatory drug (NSAID) is safer in patients with Non-steroids Exacerbated Respiratory Disease (N-ERD)? A single-center retrospective study.
Topics: Acetaminophen; Adult; Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Cyclooxygenase 2 Inhibitors; Drug Hypersensitivity; Female; Humans; Male; Meloxicam; Middle Aged; Respiratory Hypersensitivity; Respiratory Tract Diseases; Retrospective Studies | 2022 |